Centrifugal equipment for biological cell separation

Abstract

The utility model relates to the technical field of cell separation, and discloses centrifugal equipment for biological cell separation, which comprises a box body, a motor I is arranged at the bottom end in the box body, a supporting rod is arranged at the bottom end in the box body, variable-speed adjusting structures are rotatably arranged at the top ends of the motor I and the supporting rod, and a partition plate is arranged on one side in the box body. The top end of the supporting rod penetrates through the partition plate and is rotationally provided with a rotating rod, the surface of the rotating rod is sleeved with a rotor, a locking hole is formed in the top end of the rotor, an electromagnetic block is arranged at the bottom end of the rotor, a balance sensor is arranged at the bottom end of the rotor, and an annular magnetic plate is arranged at the top end of the partition plate. According to the utility model, the operation stability of the equipment is ensured, the service life of the equipment is prolonged, the operation steps are simplified, and the stepless speed change system can provide a stable speed change process and reduce vibration and noise in the biological cell separation process, so that the protection of cells is facilitated, and the accuracy of experimental results is ensured.

Description

Technical Field

[0001] The present application relates to the technical field of cell separation, and in particular to a centrifugal device for separating biological cells. Background Art

[0002] Biological cell separation centrifuge is a device specially used for cell separation and purification in the fields of biology and medicine. It separates different components (such as cells, cell fragments, viruses, proteins, etc.) in cell suspension according to differences in density, size or shape through the centrifugal force generated by high-speed rotation.

[0003] Existing cell separation centrifuges need to balance the test specimens when performing cell separation. Uneven balance of weights can lead to unstable operation of the equipment, increased vibration, and even shorten the service life of the centrifuge. Utility Model Content

[0004] In order to solve the problem, the present application provides a centrifugal device for biological cell separation.

[0005] The centrifugal device for biological cell separation provided in the present application adopts the following technical solution:

[0006] A centrifugal device for separating biological cells comprises a casing, a motor 1 is provided at the bottom end of the casing, a support rod is provided at the bottom end of the casing, a variable speed regulating structure is rotatably provided at the motor 1 and the top end of the support rod, a partition is provided at one side of the casing, a rotating rod is rotatably provided at the top end of the support rod through the partition, a rotor is sleeved on the surface of the rotating rod, a locking hole is provided at the top end of the rotor, an electromagnetic block is provided at the bottom end of the rotor, a balance sensor is provided at the bottom end of the rotor, and an annular magnetic plate is provided at the top end of the partition.

[0007] Preferably, the electromagnetic block is located directly below the locking hole, and the annular magnetic plate is located directly below the electromagnetic block.

[0008] Preferably, the speed adjustment structure includes a sliding cone, a limiting hole is opened on the surface of the sliding cone, a motor 2 is arranged at the top of the inner part of the sliding cone, a screw is connected to the output end of the motor 2, a limiting column is sleeved on the surface of the screw, and a limiting clamp is arranged on one side of the limiting column.

[0009] Preferably, there are two groups of sliding cones which are symmetrical in both positive and negative directions. Belts are sleeved on the surfaces of the two groups of sliding cones, and the belts are located in the middle of the limiting clamping plates.

[0010] Preferably, a display screen is provided on one side of the box.

[0011] Preferably, a sound insulation board is provided on the inner wall of the box.

[0012] In summary, this application includes the following beneficial technical effects:

[0013] 1. When using the equipment, put the biological cells into the locking hole in the rotor, and the balance sensor at the bottom of the rotor detects the balance of the rotor. When the rotor is found to be unbalanced, the electromagnetic block at the corresponding position increases the magnetic force, attracts the annular magnetic plate downward, increases the proportion, and keeps the rotor in a balanced state. In addition, since the annular magnetic plate is located directly below the electromagnetic block, it can be ensured that when the rotor is rotating, the electromagnetic block can also attract the annular magnetic plate evenly, so that it can always maintain a balanced state when rotating. Using this device to automatically balance the rotor ensures the stability of the equipment during operation, extends the service life of the equipment, and simplifies the operation steps;

[0014] 2. When the rotor needs to be accelerated, the belt moves on two symmetrical sliding cones. When the contact radius of the belt increases on one sliding cone, it decreases on the other sliding cone, thereby changing the transmission ratio and achieving stepless speed change. The speed and acceleration of the motor during the biological cell separation process need to be precisely controlled to avoid damage to the cells. The stepless speed change system can provide a smooth speed change process and reduce vibration and noise, which helps protect cells and ensure the accuracy of experimental results. BRIEF DESCRIPTION OF THE DRAWINGS

[0015] Figure 1 is a schematic diagram of a three-dimensional structure from a first-view perspective of an embodiment of the application;

[0016] Figure 2 is a schematic diagram of a second perspective stereoscopic structure of an embodiment of the application;

[0017] Figure 3 is a schematic diagram of a three-dimensional structure from a third viewing angle of an embodiment of the application;

[0018] Figure 4 It is a schematic diagram of the stereoscopic structure from the fourth perspective of the embodiment of the application.

[0019] Explanation of the accompanying reference numerals: 1. Box body; 2. Motor 1; 3. Support rod; 4. Speed ​​adjustment structure; 5. Partition; 6. Rotating rod; 7. Rotor; 8. Locking hole; 9. Electromagnetic block; 10. Balance sensor; 11. Annular magnetic plate; 12. Display screen; 41. Sliding cone; 42. Limiting hole; 43. Motor; 44. Screw; 45. Limiting column; 46. Limiting splint; 47. Belt. DETAILED DESCRIPTION

[0020] The following is combined with Figure 1-4 This application is described in further detail.

[0021] The present application embodiment discloses a centrifugal device for separating biological cells. Figure 1-4A centrifugal device for biological cell separation, a box body 1, a motor 2 is provided at the bottom of the box body 1, a support rod 3 is provided at the bottom of the box body 1, a speed adjustment structure 4 is provided at the top of the motor 2 and the support rod 3, a partition 5 is provided on one side of the box body 1, a rotating rod 6 is provided at the top of the support rod 3 that penetrates the partition 5 and rotates, a rotor 7 is sleeved on the surface of the rotating rod 6, a locking hole 8 is provided at the top of the rotor 7, an electromagnetic block 9 is provided at the bottom of the rotor 7, a balance sensor 10 is provided at the bottom of the rotor 7, and an annular magnetic plate 11 is provided at the top of the partition 5;

[0022] Reference Figure 2 , the electromagnetic block 9 is located directly below the locking hole 8, and the annular magnetic plate 11 is located directly below the electromagnetic block 9;

[0023] By adopting the above technical solution, each electromagnetic block 9 is located below each locking hole 8, so that the rotor 7 maintains a balanced ratio state, and the annular magnetic plate 11 is located directly below the electromagnetic block 9. When the balance of the locking holes 8 in the rotor 7 is uneven, the electromagnetic block 9 in the corresponding direction will increase the magnetic force and attract the annular magnetic plate 11 downward to increase the ratio and maintain the rotor 7 in a balanced state. In addition, since the annular magnetic plate 11 is located directly below the electromagnetic block 9, it can be ensured that when the rotor 7 is rotating, the electromagnetic block 9 can also evenly attract the annular magnetic plate 11, so that it can always maintain a balanced state when rotating.

[0024] Reference Figure 2 and 3 The speed adjustment structure 4 includes a sliding cone 41, a limiting hole 42 is provided on the surface of the sliding cone 41, a motor 43 is provided at the top of the sliding cone 41, a screw 44 is connected to the output end of the motor 43, a limiting column 45 is sleeved on the surface of the screw 44, and a limiting clamp 46 is provided on one side of the limiting column 45;

[0025] By adopting the above technical solution, the limiting clamp 46 can be driven to move up and down by the second motor 43.

[0026] Reference Figure 2 and 3 There are two groups of sliding cones 41 that are symmetrical in both directions. The surfaces of the two groups of sliding cones 41 are covered with belts 47, which are located in the middle of the limiting clamping plate 46;

[0027] By adopting the above technical solution, the belt 47 moves on two positively and negatively symmetrical sliding cones 41. When the contact radius of the belt 4 increases on one sliding cone 41, it will decrease on the other sliding cone 41, thereby changing the transmission ratio and realizing stepless speed change. The belt 47 is located in the middle of the limiting clamp 46, and the limiting clamp 46 moves up and down to limit the belt 47 to prevent the belt 47 from collapsing during rotation.

[0028] Reference Figure 1 , a display screen 12 is provided on one side of the box body 1;

[0029] By adopting the above technical solution, the centrifugal device can be regulated and used through the display screen 12.

[0030] Reference Figure 2 , a sound insulation board is provided on the inner wall of the box body 1;

[0031] By adopting the above technical solution, the sound insulation board can prevent excessive noise from affecting people when the equipment is in use.

[0032] The implementation principle of a centrifugal device for separating biological cells in an embodiment of the present application is as follows: when using the device, biological cells are placed in the locking hole 8 in the rotor 7, and the balance sensor 10 at the bottom of the rotor 7 detects the balance of the rotor 7. When the rotor 7 is found to be unbalanced, the electromagnetic block 9 at the corresponding position increases the magnetic force, attracts the annular magnetic plate 11 downward, increases the ratio, and keeps the rotor 7 in a balanced state. Moreover, since the annular magnetic plate 11 is located directly below the electromagnetic block 9, it can be ensured that when the rotor 7 is rotating, the electromagnetic block 9 can also uniformly attract the annular magnetic plate 11, so that it can always maintain a balanced state when rotating.

[0033] When the rotor 7 needs to be accelerated, the belt 47 moves on two symmetrical sliding cones 41. When the contact radius of the belt 4 increases on one sliding cone 41, it will decrease on the other sliding cone 41, thereby changing the transmission ratio and realizing stepless speed change. The belt 47 is located in the middle of the limit clamp 46. The limit clamp 46 moves up and down to limit the belt 47 to prevent the belt 47 from collapsing during rotation. The use of this device can automatically balance the rotor 7, ensure the stability of the equipment during operation, extend the service life of the equipment, simplify the operating steps, and in the process of biological cell separation, the speed and acceleration of the motor need to be precisely controlled to avoid damage to the cells. The stepless speed change system can provide a smooth speed change process and reduce vibration and noise, which helps to protect cells and ensure the accuracy of experimental results.

[0034] Finally, a few points should be explained: First, in the description of this application, it should be noted that, unless otherwise specified and limited, the terms "installed", "connected", and "connected" should be understood in a broad sense, which may refer to mechanical connection or electrical connection, or internal communication between two components, or direct connection. "upper", "lower", "left", "right", etc. are only used to indicate relative positional relationships. When the absolute position of the object being described changes, the relative positional relationship may change;

[0035] Secondly: In the drawings of the embodiments disclosed in the present utility model, only the structures related to the embodiments disclosed in the present utility model are involved, and other structures can refer to the general design. In the absence of conflict, the same embodiment and different embodiments of the present utility model can be combined with each other;

[0036] Finally: The above description is only a preferred embodiment of the present utility model and is not intended to limit the present utility model. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of the present utility model should be included in the protection scope of the present utility model.

[0037] The above are all preferred embodiments of the present application, and the protection scope of the present application is not limited thereto. Therefore, any equivalent changes made according to the structure, shape, and principle of the present application should be included in the protection scope of the present application.

Claims

1. A centrifugal device for biological cell separation, comprising a housing (1), characterized in that: A motor (2) is provided at the bottom of the box body (1), a support rod (3) is provided at the bottom of the box body (1), a speed adjustment structure (4) is rotatably provided at the top of the motor (2) and the support rod (3), a partition (5) is provided on one side of the box body (1), a rotating rod (6) is rotatably provided at the top of the support rod (3) penetrating the partition (5), a rotor (7) is sleeved on the surface of the rotating rod (6), a locking hole (8) is provided at the top of the rotor (7), an electromagnetic block (9) is provided at the bottom of the rotor (7), a balance sensor (10) is provided at the bottom of the rotor (7), and an annular magnetic plate (11) is provided at the top of the partition (5).

2. A centrifugal device for biological cell separation according to claim 1, characterized in that: The electromagnetic block (9) is located directly below the locking hole (8), and the annular magnetic plate (11) is located directly below the electromagnetic block (9).

3. A centrifugal device for biological cell separation according to claim 1, characterized in that: The speed adjustment structure (4) comprises a sliding cone (41), a limiting hole (42) is provided on the surface of the sliding cone (41), a second motor (43) is provided at the top end of the interior of the sliding cone (41), a screw rod (44) is connected to the output end of the second motor (43), a limiting column (45) is sleeved on the surface of the screw rod (44), and a limiting clamping plate (46) is provided on one side of the limiting column (45).

4. A centrifugal device for biological cell separation according to claim 3, characterized in that: The sliding cones (41) are provided in two groups and are symmetrical in both positive and negative directions. The surfaces of the two groups of sliding cones (41) are sleeved with belts (47), and the belts (47) are located in the middle of the limiting clamping plate (46).

5. A centrifugal device for biological cell separation according to claim 1, characterized in that: A display screen (12) is provided on one side of the box body (1).

6. A centrifugal device for biological cell separation according to claim 1, characterized in that: The inner wall of the box body (1) is provided with a sound insulation board.

Images