Biological medicine capping freeze dryer
By designing the combined structure of the combined structure in the frozen dryer, and using the clamping unit to hold the Xilin bottle, the Xilin bottle is used to hold the problem of the frozen dryer's offset or dumping during the stitching process. The stability and safety of the frozen dried process.
Patent Information
- Application Number
- CN202421220921.4
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-05-31
- Publication Date
- 2025-01-28
- Estimated Expiration
- 2034-05-31
AI Technical Summary
The existing freeze-dryer has a single structure, which causes the cilrin bottle to be easily offset or dumped during the capping process, causing losses.
Design a biomedical pressure cover frozen dryer, adopts a combined structure of placing disk and cover plate, and moves to the Xilin bottle by driving the cover of the re -screw to drive the cover. , Use the holding unit to hold the Xilin bottle fixedly holding.
Effectively prevent the Xilin bottle from shifting or dumping during the cover process, avoid material leakage, and ensure the stability and safety of the frozen drying process.
Smart Images

Figure CN222418249U_ABST
Abstract
Description
Technical Field
[0001] The present application relates to the technical field of freeze dryers, and in particular to a biomedical capping freeze dryer. Background Art
[0002] Capped freeze dryers are widely used in the drying process of biological drugs. Biological drugs are generally filled in vials with rubber stoppers. Capped freeze dryers are used to freeze-dry the filled vials, evaporate the water in the mixture in the vials, and complete the stoppering and sealing of the vials, which can effectively prevent the drugs from being contaminated. When the capped freeze dryer is drying the materials inside the vials, the vials are usually placed on a tray for freeze drying.
[0003] The existing placement plate structure is relatively simple, so that when the freeze dryer is capping, the vials will be offset or tipped over, causing damage to the vials and leakage of materials inside the vials, resulting in losses. Therefore, improvements are now made to a biopharmaceutical capping freeze dryer. Utility Model Content
[0004] In view of the deficiencies of the prior art, the present application provides a biopharmaceutical capping freeze dryer, which overcomes the deficiencies of the prior art and aims to solve the problem that the placement plate structure is relatively simple, causing the vials to shift or tip over when the freeze dryer is capping.
[0005] To achieve the above-mentioned objectives, the present application provides the following technical solutions: a biopharmaceutical capping freeze dryer, comprising a freeze dryer body, a placing plate fixedly installed inside the freeze dryer body, three sliding rods and a reciprocating screw rod slidingly passing through the inside of the placing plate, the two ends of the three sliding rods are fixedly installed on the inner wall of the freeze dryer body, the two ends of the reciprocating screw rod are rotatably installed on the inner wall of the freeze dryer body, the outer surface of the reciprocating screw rod is located above the placing plate and is threadedly connected with a cover plate, a plurality of placing grooves are provided on the upper surface of the placing plate, an adjustment groove is provided inside the placing plate on one side of the placing groove, and a clamping unit is provided inside the adjustment groove.
[0006] By adopting the above technical scheme, a reciprocating screw is used to drive the cover plate to move downward to cap the vials on the placement tray, a placement groove is opened on the upper surface of the placement tray for placing the vials, and the vials in the placement groove are fixedly clamped by adjusting the clamping unit inside the groove, thereby preventing the vials from shifting or tipping over when the freeze dryer body is capping, thereby avoiding leakage of materials inside the vials and causing losses.
[0007] As a preferred technical solution of the present application, the number of the placement trays and cover plates is three, and the three placement trays and cover plates are divided into three groups one by one, and the distance between each group of placement trays and cover plates is equal.
[0008] By adopting the above technical solution, the reciprocating screw can simultaneously drive the three cover plates to move downward when rotating, and the three cover plates apply the same extrusion force to the vials on the three placement trays, so the vials will not be damaged due to uneven force.
[0009] As a preferred technical solution of the present application, the clamping unit includes an adjustment spring fixedly connected to the inner wall of the adjustment groove, the other end of the adjustment spring is fixedly connected to an adjustment block, and one end of the adjustment block is fixedly installed with a rubber clamping pad.
[0010] By adopting the above technical solution, the position of the adjustment block and the rubber clamping pad is adjusted by utilizing the elastic force of the adjustment spring, so that the rubber clamping pad fits the outer wall of the vials of different sizes within a certain range, thereby ensuring the clamping effect of the clamping unit.
[0011] As a preferred technical solution of the present application, four adjustment grooves and four clamping units are distributed around the plurality of placement grooves, and the four adjustment grooves and clamping units are evenly distributed in a circular array with respect to the placement grooves.
[0012] By adopting the above technical solution, the vial can be clamped and fixed from multiple directions to ensure the stability of the vial when it is placed, and it will not deviate or tip over during the capping process.
[0013] As a preferred technical solution of the present application, a worm wheel is fixedly sleeved on the outer surface of the reciprocating screw near the upper end, a worm is meshingly connected to one side of the worm wheel, a drive motor is fixedly installed on the top of the freeze dryer body, and the worm is fixedly connected to the output end of the drive motor.
[0014] By adopting the above technical solution, the reciprocating screw rod can be driven to rotate by the driving motor through the worm wheel and the worm.
[0015] As a preferred technical solution of the present application, a sealing door is hinged at the front end of the freeze dryer body, a positioning block is fixedly installed on one side of the freeze dryer body, a fixing block is fixedly installed on one side of the sealing door, and the fixing block is threadedly connected to the fixing block through a fixed threaded rod.
[0016] By adopting the above technical solution, the sealing of the internal space of the freeze dryer body is ensured when it is working.
[0017] Compared with the prior art, the beneficial effects of the utility model are:
[0018] In the utility model, a reciprocating screw rod is driven by a driving motor to rotate and drive the cover plate to move downward to cap the vials on the placing tray. A placing groove is provided on the upper surface of the placing tray for placing the vials. The vials in the placing groove are fixedly clamped by adjusting the clamping unit inside the groove, thereby preventing the vials from shifting or tipping over when the freeze dryer body is capping, thereby avoiding leakage of materials inside the vials and causing losses.
[0019] With reference to the following description and drawings, specific embodiments of the present invention are disclosed in detail, indicating the manner in which the principles of the present invention can be adopted. It should be understood that the scope of the embodiments of the present invention is not limited thereby. BRIEF DESCRIPTION OF THE DRAWINGS
[0020] The accompanying drawings are used to provide a further understanding of the present invention and constitute a part of the specification. Together with the embodiments of the present invention, they are used to explain the present invention and do not constitute a limitation of the present invention. In the accompanying drawings:
[0021] Figure 1 This is a schematic diagram of the internal structure of this application;
[0022] Figure 2 This is a schematic diagram of the front structure of this application;
[0023] Figure 3 It is a schematic diagram of the local structure of this application;
[0024] Figure 4 For this application Figure 3 Schematic cross-sectional view at point A.
[0025] In the figure: 1. freeze dryer body; 2. placement plate; 3. cover plate; 4. reciprocating screw; 5. sliding rod; 6. worm gear; 7. worm; 8. driving motor; 9. clamping unit; 91. adjusting spring; 92. adjusting block; 93. rubber clamping pad; 10. placement slot; 11. adjusting slot; 12. sealing door; 13. positioning block; 14. fixing block; 15. fixing threaded rod. DETAILED DESCRIPTION
[0026] In order to make the technical means, creative features, objectives and effects achieved by the present invention easy to understand, the present invention is further described below in conjunction with specific implementation methods.
[0027] like Figure 1 - Figure 4As shown, a biomedical capping freeze dryer provided in this embodiment includes a freeze dryer body 1, a placement tray 2 is fixedly installed inside the freeze dryer body 1, three slide bars 5 and a reciprocating screw rod 4 are slidably penetrated inside the placement tray 2, the two ends of the three slide bars 5 are fixedly installed on the inner wall of the freeze dryer body 1, the two ends of the reciprocating screw rod 4 are rotatably installed on the inner wall of the freeze dryer body 1, the outer surface of the reciprocating screw rod 4 is located above the placement tray 2 and is threadedly connected with a cover plate 3, the upper surface of the placement tray 2 is provided with a plurality of placement grooves 10, and the inner position of the placement tray 2 is An adjusting groove 11 is provided on one side of the placement groove 10, and a clamping unit 9 is provided inside the adjusting groove 11. When in use, the reciprocating screw rod 4 is used to drive the cover plate 3 to move downward to cap the vials on the placement tray 2. The placement groove 10 is provided on the upper surface of the placement tray 2 for placing the vials, and the vials inside the placement groove 10 are fixedly clamped by the clamping unit 9 inside the adjusting groove 11, so as to prevent the vials from shifting or tipping over when the freeze dryer body 1 is capping, thereby avoiding leakage of materials inside the vials and causing losses.
[0028] In this embodiment, if Figure 1 and 3 As shown, there are three placement trays 2 and three cover plates 3, which are respectively divided into three groups corresponding to each other, and the distance between each group of placement trays 2 and cover plates 3 is equal. When in use, the reciprocating screw 4 can simultaneously drive the three cover plates 3 to move downward, and the extrusion pressure applied by the three cover plates 3 to the vials on the three placement trays 2 is also the same, so the vials will not be damaged due to uneven force.
[0029] In this embodiment, if Figure 3 and 4 As shown, the clamping unit 9 includes an adjusting spring 91 fixedly connected to the inner wall of the adjusting groove 11, the other end of the adjusting spring 91 is fixedly connected to an adjusting block 92, and one end of the adjusting block 92 is fixedly installed with a rubber clamping pad 93. When in use, the positions of the adjusting block 92 and the rubber clamping pad 93 are adjusted by utilizing the elastic force of the adjusting spring 91, so that the rubber clamping pad 93 fits the outer wall of the vials of different sizes within a certain range, thereby ensuring the clamping effect of the clamping unit 9.
[0030] In this embodiment, if Figure 3 and 4 As shown, four adjustment grooves 11 and four clamping units 9 are distributed around the plurality of placement grooves 10. The four adjustment grooves 11 and the clamping units 9 are evenly distributed in a circular array with respect to the placement grooves 10. When in use, the vial is clamped and fixed from multiple directions to ensure the stability of the vial when placed, and prevent it from being offset or tipped over during the capping process.
[0031] In this embodiment, if Figure 1As shown, a worm wheel 6 is fixedly sleeved on the outer surface of the reciprocating screw 4 near the upper end, a worm 7 is meshingly connected to one side of the worm wheel 6, a drive motor 8 is fixedly installed on the top of the freeze dryer body 1, and the worm 7 is fixedly connected to the output end of the drive motor 8. When in use, the worm wheel 6 and the worm 7 are used to facilitate the drive motor 8 to drive the reciprocating screw 4 to rotate.
[0032] In this embodiment, if Figure 2 As shown, a sealing door 12 is hinged at the front end of the freeze dryer body 1, a positioning block 13 is fixedly installed on one side of the freeze dryer body 1, and a fixing block 14 is fixedly installed on one side of the sealing door 12. The fixing block 14 is threadedly connected with the fixing block 14 through a fixing threaded rod 15. When in use, the sealing of the internal space of the freeze dryer body 1 is ensured when it is working.
[0033] The working principle of the utility model is as follows: when using a biopharmaceutical capping freeze dryer of the present application, the reciprocating screw 4 is driven by the driving motor 8 to rotate and drive the cover plate 3 to move downward to cap the vials on the placement tray 2, and a placement groove 10 is opened on the upper surface of the placement tray 2 for placing the vials, and the vials located inside the placement groove 10 are fixedly clamped by the clamping unit 9 inside the adjustment groove 11, so as to prevent the vials from shifting or tipping over when the freeze dryer body 1 is capping, thereby avoiding leakage of materials inside the vials and causing losses.
[0034] The utility model is described above in conjunction with specific implementation methods, but those skilled in the art should be aware that these descriptions are exemplary and not limiting the scope of protection of the utility model. Those skilled in the art can make various variations and modifications to the utility model based on the spirit and principles of the utility model, and these variations and modifications are also within the scope of the utility model.
Claims
1. A biomedical capping freeze dryer, comprising a freeze dryer body (1), characterized in that: A placement plate (2) is fixedly installed inside the freeze dryer body (1), and three sliding rods (5) and a reciprocating screw (4) are slidably penetrated inside the placement plate (2). The two ends of the three sliding rods (5) are fixedly installed on the inner wall of the freeze dryer body (1), and the two ends of the reciprocating screw (4) are rotatably installed on the inner wall of the freeze dryer body (1). The outer surface of the reciprocating screw (4) is located above the placement plate (2) and is threadedly connected to a cover plate (3). A plurality of placement grooves (10) are provided on the upper surface of the placement plate (2), and an adjustment groove (11) is provided inside the placement plate (2) on one side of the placement groove (10), and a clamping unit (9) is provided inside the adjustment groove (11).
2. A biomedical capping freeze dryer according to claim 1, characterized in that: The number of the placement trays (2) and the cover plates (3) are both three, and the three placement trays (2) and the cover plates (3) are respectively divided into three groups in a one-to-one correspondence, and the distance between the placement trays (2) and the cover plates (3) in each group is equal.
3. A biomedical capping freeze dryer according to claim 1, characterized in that: The clamping unit (9) comprises an adjusting spring (91) fixedly connected to the inner wall of the adjusting groove (11); the other end of the adjusting spring (91) is fixedly connected to an adjusting block (92); and one end of the adjusting block (92) is fixedly mounted with a rubber clamping pad (93).
4. A biopharmaceutical capping freeze dryer according to claim 1, characterized in that: Four adjustment slots (11) and four clamping units (9) are distributed around the plurality of placement slots (10), and the four adjustment slots (11) and the clamping units (9) are evenly distributed in a circular array with respect to the placement slots (10).
5. The biopharmaceutical capping freeze dryer according to claim 1, characterized in that: A worm wheel (6) is fixedly sleeved on the outer surface of the reciprocating screw (4) near the upper end, and a worm (7) is meshingly connected to one side of the worm wheel (6). A driving motor (8) is fixedly installed on the top of the freeze dryer body (1), and the worm (7) is fixedly connected to the output end of the driving motor (8).
6. A biomedical capping freeze dryer according to claim 1, characterized in that: A sealing door (12) is hingedly connected to the front end of the freeze dryer body (1); a positioning block (13) is fixedly installed on one side of the freeze dryer body (1); a fixing block (14) is fixedly installed on one side of the sealing door (12); and the fixing block (14) is threadedly connected to the fixing block (14) via a fixing threaded rod (15).
Citation Information
Cited By
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