Pathological tissue slice dyeing machine

Abstract

The utility model discloses a pathological tissue slice dyeing machine, which is characterized in that a lifting piece is arranged in a dyeing tank, a traditional mode of driving a glass slide to reciprocate up and down by a moving mechanism is replaced by a mode of changing the liquid level of a dyeing reagent on the basis of a mode of improving the dyeing efficiency during dipping, and the dyeing efficiency is improved on the premise of having the same effect. The glass slide does not need to move up and down, the moving mechanism is released, and the moving mechanism can move another glass slide hanging basket for dyeing treatment within the time, so that the working efficiency is improved.

Description

Technical Field

[0001] The utility model belongs to the field of pathological tissue section staining equipment, and specifically relates to a pathological tissue section staining machine. Background Art

[0002] Pathological tissue sections are thin slices prepared from patient tissue samples for pathological examination and diagnosis. The cut tissue specimens are embedded and then cut into extremely thin slices by a tissue slicer. The cut tissue sections are transferred to glass slides, then solidified, dewaxed and stained, and a staining machine is used in the staining process.

[0003] A Chinese patent with authorization announcement number CN208505728U discloses an automatic pathological tissue sectioning and staining machine, including a frame, the bottom of the frame is a concave cylinder, the concave cylinder is provided with a staining cylinder and other functional cylinders, a conventional tissue slicer is provided at the top of the front end of the machine, a slide is provided at the slice outlet of the tissue slicer, two parallel slide bars are provided at the top of the front of the frame, bearings are provided on the slide bars, a hanging basket is hung on the bearings through telescopic rods, a hanging basket loaded with a slide glass coated with cells is provided at the slice outlet of the tissue slicer, the telescopic rod is controlled by a cylinder provided at the rear of the frame, the vertical height of the hanging basket is adjusted so that the hanging basket can be immersed in the staining cylinder, the bearing is driven by a stepper motor provided at the rear of the frame, moves forward along the slide bar, and the pathological tissue sectioning mechanism is set on the staining machine, so that the function of the existing staining machine is increased, and at the same time, the staining efficiency is improved and the time is shorter.

[0004] The above technical solution has the following defects:

[0005] As for improving the staining efficiency by means of an ultrasonic vibrator, although the staining reagent can be vibrated to increase the staining effect, the thickness of the glass slide is usually standardized, generally between 1.0 mm and 1.5 mm, and the standard thickness of the pathological tissue section is 3 to 5 microns. Vibration may cause the glass slide to break. At the same time, only one hanging basket can be stained during the whole process, and the work efficiency is not high. Utility Model Content

[0006] In view of the above defects, the utility model provides a pathological tissue section staining machine, including a staining machine body, wherein a moving mechanism for moving a glass slide and a staining cabin for staining are installed inside the staining machine body, the first vertical column on the left side of the staining cabin is a sample slot, and the vertical columns on the right side are all staining slots, and a glass hanging basket for fixing the glass slide is placed in the sample slot, and a sealing cover for sealing is hinged at the operation window of the staining machine body through a pin shaft;

[0007] The output end of the mobile mechanism is equipped with a suspension mechanism for suspending a glass-carrying hanging basket, and the suspension mechanism includes two suspension plates, and the two suspension plates are provided with matching fitting grooves on one side close to the output end of the mobile mechanism, and an electric slider is installed inside each of the matching grooves, and the two sides of the output end of the mobile mechanism are respectively provided with slide rails matching the two electric sliders, and the bottom ends of the front and rear sides of each suspension plate are fixed with hooks matching the suspension plate, and the bottom of the mobile mechanism is also provided with a limit plate for fixing the two suspension plates;

[0008] The staining tank includes a tank body and a liquid level lifting mechanism located inside the tank body. The front and rear ends of the tank body are provided with slots for limiting the hanging of a glass-carrying hanging basket. The front and back sides of the tank body are respectively integrally formed with convex columns located at the same horizontal height. Lifting rods for lifting the tank body are sleeved on the two convex columns. The liquid level lifting mechanism includes a lifting member located in a groove inside the tank body. A water baffle plate for sealing is fixed to the top of the lifting member.

[0009] Furthermore, a light shielding film is attached to the sealing cover, and a sealing strip is fixed to the edge of the sealing cover.

[0010] The technical solution has a certain shading effect and also has good sealing properties to prevent heat dissipation during heating.

[0011] Furthermore, the hook includes a left hook and a right hook, and the hooks are located on the same straight line.

[0012] Through the above technical solution, the glass carrier basket can be lifted from two directions.

[0013] Furthermore, the diameter of the limit plate is larger than the diameter of the two fitting grooves when the telescopic end of the moving mechanism is attached, and a threaded groove is provided at the bottom end of the telescopic end of the moving mechanism, and a screw for threaded connection is fixed in the middle of the limit plate.

[0014] Through the above technical solution, the movable installation method is adopted to limit the bottom of the two suspension plates.

[0015] Furthermore, the insertion end of the glass-slide hanging basket is provided with a plurality of groups of trapezoidal partitions for partitioning the glass slides, and the front and rear ends of the glass-slide hanging basket are provided with integrally formed hook-shaped protrusions for matching with the hooks.

[0016] Through the above technical solution, the trapezoidal partition is convenient for separating and fixing multiple slides, and the hook-shaped protrusion can be fitted with the hook and lifted by it.

[0017] Furthermore, a group of limiting protrusions for preventing the lifting rod from rotating are integrally formed at the front and rear ends of the glass-carrying hanging basket.

[0018] Through the above technical solution, the rotation angle of the lifting rod can be limited when it is lifted, and the bottom glass-carrying hanging basket can be kept in a vertical downward state by its own gravity, which is convenient for transportation operations.

[0019] Compared with the prior art, the utility model has the following beneficial effects:

[0020] As for the method of improving the staining efficiency during dipping, the method of changing the liquid level of the staining reagent is adopted to replace the traditional form of the moving mechanism driving the glass slide to move up and down. Under the premise of having the same effect, there is no need for the glass slide itself to move up and down, thus releasing the moving mechanism. During this time, the moving mechanism can move another glass slide basket for staining, thereby improving work efficiency. BRIEF DESCRIPTION OF THE DRAWINGS

[0021] Figure 1 It is a three-dimensional diagram of the utility model.

[0022] Figure 2 It is a schematic diagram of the connection between the moving mechanism and the suspension mechanism in the utility model.

[0023] Figure 3 It is a three-dimensional diagram of the dyeing tank in the present invention.

[0024] Figure 4 It is a cross-sectional view of the tank body in the utility model from the side.

[0025] In the figure: 1. dyeing machine body; 2. sealing cover; 3. moving mechanism; 4. hanging mechanism; 41. hanging plate; 42. fitting groove; 43. electric slider; 44. slide rail; 45. hook; 46. limit plate; 5. dyeing tank; 51. tank body; 52. card slot; 53. convex column; 54. lifting rod; 55. limit protrusion; 56. water retaining plate; 57. lifting part; 6. glass hanging basket. DETAILED DESCRIPTION

[0026] In order to facilitate the understanding of the present invention, the present invention will be described more fully below with reference to the relevant drawings. The drawings provide embodiments of the device. However, the device can be implemented in many different forms and is not limited to the embodiments described herein. On the contrary, the purpose of providing these embodiments is to make the disclosure of the present invention more thorough and comprehensive.

[0027] In the description of the present invention, it should be noted that, unless otherwise clearly specified and limited, the terms "installed", "connected", and "set" should be understood in a broad sense, for example, they can be fixedly connected or set, or detachably connected or set, or integrally connected or set. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0028] Example

[0029] like Figure 1-4 As shown, the present embodiment provides a pathological tissue section staining machine, including a staining machine body 1, wherein a moving mechanism 3 for moving a glass slide and a staining cabin for staining are installed inside the staining machine body 1, wherein the first vertical column on the left side of the staining cabin is a sample slot, and the vertical columns on the right side are all staining slots 5 (for storing different staining reagents), and a glass hanging basket 6 for fixing the glass slide is placed in the sample slot. In detail, the insertion end of the glass hanging basket 6 is provided with a plurality of groups of trapezoidal partitions for separating the glass slides, and the trapezoidal partitions are convenient for separating and limiting a plurality of glass slides, and the front and rear ends of the glass hanging basket 6 are provided with an integrally formed curved hook-shaped protrusion for matching with the hook 45, and the curved hook-shaped protrusion can be matched with the hook 45 and lifted by it; and the front and rear ends of the glass hanging basket 6 are integrally formed with a group of groups for blocking The limiting protrusions 55 that stop the lifting rod 54 from rotating have two functions, respectively, to enable the lifting rod 54 to be located on the left side when located inside the staining machine body 1, so as not to affect the transportation operation of the slide at the top opening of the trough body 51; and when the trough body 51 needs to be taken out for cleaning, the lifting rod 54 is pulled up and along with the gravity of the internal staining reagent, it is blocked by the limiting protrusion 55 on the right side, so that a good vertical state can be maintained to prevent the staining reagent from spilling due to rollover; a sealing cover 2 for sealing is hingedly connected to the operating window of the staining machine body 1 through a pin shaft, preferably, a shading film is attached to the sealing cover 2, which has a certain shading property, and a sealing strip is fixed at the edge of the sealing cover 2, which has good sealing property to prevent heat dissipation during heating.

[0030] The output end of the moving mechanism 3 is equipped with a suspension mechanism 4 for hanging a glass carrier basket 6. It should be noted that the moving mechanism 3 is the same as the moving device in the traditional dyeing machine, and can be realized by installing an electric slide or a mechanical arm on the top of the dyeing machine and adding an electric telescopic rod on the bottom. It will not be described in detail here; the suspension mechanism 4 includes two suspension plates 41, and the two suspension plates 41 are provided with a fitting groove 42 adapted thereto on one side close to the output end (i.e., the telescopic end) of the moving mechanism 3, and an electric slider 43 is installed inside each fitting groove 42. The two sides of the output end of the moving mechanism 3 are respectively provided with slide rails 44 adapted to the two electric sliders 43, and the bottom ends of the front and rear sides of each suspension plate 41 are fixed with hooks 45 adapted to the suspension plate 41. In detail, the hook 45 includes The left hook and the right hook are located on the same straight line. Their function is that when a glass slide is stained and moved to another glass hanging basket 6 for hanging and moving, it is not necessary to move to a single side like traditional equipment (such as the left hook is moved to the left and the right hook is moved to the right), and it can be directly lifted from the adjacent side to improve work efficiency; the bottom of the moving mechanism 3 is also provided with a limiting plate 46 for fixing the two hanging plates 41. In detail, the diameter value of the limiting plate 46 is greater than the diameter value of the two fitting grooves 42 when the moving mechanism 3 is attached to the telescopic end, and the bottom end of the telescopic end of the moving mechanism 3 is provided with a threaded groove, and a screw for threaded connection is fixed in the middle of the limiting plate 46. After the limiting plate 46 is threadedly connected, the bottom of the hanging plates 41 on both sides can be limited.

[0031] The staining tank 5 includes a tank body 51 and a liquid level lifting mechanism located inside the tank body 51. The front and rear ends of the tank body 51 are provided with a clamping groove 52 for limiting the hanging of the glass-carrying hanging basket 6, which is convenient for limiting the position of the glass-carrying hanging basket 6 after it is placed inside. The front and back sides of the tank body 51 are respectively integrally formed with convex columns 53 located at the same horizontal height. The two convex columns 53 are sleeved with lifting rods 54 for lifting the tank body 51. The two convex columns 53 play a role in limiting the lifting rods 54, so that it has a rotation function. The liquid level lifting mechanism includes a lifting member 57 located in the groove inside the tank body 51. The top of the lifting member 57 is fixed with a water baffle 56 for sealing. The water baffle 56 is made of corrosion-resistant rubber material, and its four sides should be in contact with the inner wall of the tank body 51 to achieve a sealing effect (it should be noted that when the inner wall surface of the tank body 51 is not processed smoothly enough, the water baffle 56 can be omitted, so that the lifting member 57 is directly in contact with the staining reagent); it should be noted that , the lifting member 57 is an inflatable airbag structure, the surface of which is coated with corrosion-resistant paint, and the bottom end of the inflatable airbag is provided with an air inlet valve, which should penetrate the inner bottom wall of the tank body 51. At the same time, a dual-purpose air pump should be provided inside the dyeing machine body 1, and it should be connected with each air inlet valve through a shunt pipe. A solenoid valve should also be provided at the connection point to open the air inlet valve at the tank body 51 in the dyeing use state, so that the inflatable airbag can be inflated and exhausted, so as to adjust the liquid level of the dyeing reagent; for the case where the inner wall inside the tank body 51 is a vertical smooth surface, the structure of the electric push rod can also be directly adopted to achieve it, that is, a telescopic hole is opened at the bottom end of each tank body 51, and a number of electric push rods corresponding to the telescopic holes are provided at the corresponding dyeing machine body 1, and the telescopic end of the electric push rod penetrates the telescopic hole to be fixed to the bottom of the water baffle 56 (simulating the work of the push rod and rubber plug inside the syringe, and adopting the same movable connection method to facilitate subsequent plugging and unplugging).

[0032] It should be noted that, in this embodiment, the water level of the staining reagent inside the trough body 51 should be at 1 / 2 of the internal depth of the trough body 51, and when the water retaining plate 56 is in the topmost movement state, the internal water level should be at 3 / 4, so as to satisfy the movement mode of replacing the traditional slide body for up and down reciprocating insertion, keep it still, prevent the slide from slipping or breaking, and at the same time meet good staining efficiency.

[0033] The pathological tissue section staining machine described in this embodiment uses the front control panel to fill in the staining reagent situation according to the actual situation, and then the central control system inside the staining machine controls the moving mechanism 3 to perform corresponding movements, so that the hanging mechanism 4 hangs the trough body 51, so that the glass slides inside can undergo the preset staining process; at the same time, two groups of glass slide baskets 6 can be stained simultaneously to improve work efficiency, which is the same as the control system inside the existing TR-D24 tissue staining machine. When the first glass slide basket 6 is placed in the corresponding trough body 51 for staining, the moving mechanism 3 transports the second glass slide basket 6 to the corresponding trough body 51, and then moves the first glass slide basket 6 to the subsequent trough body 51, and repeats this process. In this embodiment, the design of the two-way hook 45 is adopted, so there is no need to move the moving mechanism 3 to the specified side (i.e., one side of the traditional one-way hook 45), and the glass slide basket 6 can be directly moved from the adjacent side to be suspended, thereby improving work efficiency.

[0034] It should be noted that the structure described in the utility model can be implemented in a variety of different forms and is not limited to the described embodiments. Any equivalent transformations made by ordinary technicians in this field using the contents of the utility model specification and drawings, or directly or indirectly applied to other related technical fields, such as the loading and unloading of other items, are included in the protection scope of the utility model.

Claims

1. A pathological tissue section staining machine, comprising a staining machine body, characterized in that: A moving mechanism for moving the glass slide and a staining cabin for staining are installed inside the staining machine body. The first vertical column on the left side of the staining cabin is a sample slot, and the vertical columns on the right side are all staining slots. A glass hanging basket for fixing the glass slide is placed in the sample slot. A sealing cover for sealing is hinged at the operation window of the staining machine body through a pin shaft. The output end of the mobile mechanism is equipped with a suspension mechanism for suspending a glass-carrying hanging basket, and the suspension mechanism includes two suspension plates, and the two suspension plates are provided with matching fitting grooves on one side close to the output end of the mobile mechanism, and an electric slider is installed inside each of the matching grooves, and the two sides of the output end of the mobile mechanism are respectively provided with slide rails matching the two electric sliders, and the bottom ends of the front and rear sides of each suspension plate are fixed with hooks matching the suspension plate, and the bottom of the mobile mechanism is also provided with a limit plate for fixing the two suspension plates; The staining tank includes a tank body and a liquid level lifting mechanism located inside the tank body. The front and rear ends of the tank body are provided with slots for limiting the hanging of a glass-carrying hanging basket. The front and back sides of the tank body are respectively integrally formed with convex columns located at the same horizontal height. Lifting rods for lifting the tank body are sleeved on the two convex columns. The liquid level lifting mechanism includes a lifting member located in a groove inside the tank body. A water baffle plate for sealing is fixed to the top of the lifting member.

2. A pathological tissue section staining machine as claimed in claim 1, characterized in that: A light shielding film is attached to the sealing cover, and a sealing strip is fixed to the edge of the sealing cover.

3. A pathological tissue section staining machine as claimed in claim 1, characterized in that: The hooks include a left hook and a right hook, and are located on the same straight line.

4. A pathological tissue section staining machine as claimed in claim 1, characterized in that: The diameter of the limit plate is larger than the diameter of the two fitting grooves when the two fitting grooves are attached to the telescopic end of the moving mechanism, and a threaded groove is provided at the bottom end of the telescopic end of the moving mechanism, and a screw for threaded connection is fixed in the middle of the limit plate.

5. A pathological tissue section staining machine as claimed in claim 1, characterized in that: The insertion end of the glass-carrying hanging basket is provided with a plurality of groups of trapezoidal partitions for partitioning the glass slides, and the front and rear ends of the glass-carrying hanging basket are both provided with integrally formed hook-shaped protrusions for matching with the hooks.

6. A pathological tissue section staining machine as claimed in claim 1, characterized in that: A group of limiting protrusions for preventing the lifting rod from rotating are integrally formed at the front and rear ends of the glass-carrying hanging basket.

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