Cell separation device for cell research

Abstract

A cell separation device for cell research comprises a cylinder, the top of the cylinder is open and rotatably provided with a top cover, a partition plate is fixedly installed in the cylinder, a driving motor is arranged below the partition plate, the driving motor is fixedly installed on the cylinder, and an output shaft of the driving motor penetrates through the partition plate and is fixedly provided with a vertical shaft; a first rotating plate is arranged at the upper end of the vertical shaft, a plurality of placing grooves are formed in the first rotating plate, a second rotating plate is arranged at the upper end of the vertical shaft, and a plurality of placing holes corresponding to the placing grooves are formed in the second rotating plate. When the diameter of the test tube is smaller than that of the placing hole, the vertical tube is rotated to drive the upper end of the elastic rubber cylinder to rotate, the lower end of the elastic rubber cylinder does not rotate, the two ends of the elastic rubber cylinder rotate relatively, the middle of the elastic rubber cylinder is tightened inwards, and the middle of the elastic rubber cylinder is tightly attached to the test tube, so that the test tube is fixed. And the fixing device can meet market requirements and is suitable for popularization.

Description

Technical Field

[0001] The utility model belongs to the field of cell separation and extraction, in particular to a cell separation device for cell research. Background Art

[0002] Cells are extremely tiny and can only be seen under a microscope. They have various shapes. In the process of cell research, separation devices are often needed to separate cells to improve the effect of cell research. The patent with authorization announcement number CN218089499U: "A mesenchymal stem cell separation and extraction device" discloses a cell separation and extraction device. However, when the diameter of the test tube in the device is smaller than the diameter of the socket, it is necessary to rotate the fourth connecting disk so that the socket on the fourth connecting disk is staggered with the socket aligned on the third connecting disk. While rotating the fourth connecting disk, the sockets aligned on the first connecting disk and the second connecting disk will also be staggered, but the staggered sockets are not regular circles and cannot fit with the test tubes, and the clamping is unstable. Therefore, we designed a cell separation device for cell research. Utility Model Content

[0003] The utility model provides a cell separation device for cell research, which is used to solve the defects in the prior art.

[0004] The utility model is realized through the following technical solutions:

[0005] A cell separation device for cell research comprises a cylinder, the top of the cylinder is open and a top cover is rotatably installed, a partition is fixedly installed in the cylinder, a driving motor is arranged below the partition, the driving motor is fixedly installed on the cylinder, the output shaft of the driving motor passes through the partition and is fixedly installed on a vertical axis, a first rotating plate is fixedly installed on the vertical axis, a plurality of placement grooves are provided on the first rotating plate, a second rotating plate is provided on the upper end of the vertical axis, a plurality of placement holes are provided on the second rotating plate corresponding to the placement grooves, and the device is characterized in that vertical tubes are respectively arranged above the placement holes, the vertical tubes are respectively rotatably installed on the second rotating plate through bearings, a limiting device for limiting the arbitrary rotation of the vertical tubes is provided on the second rotating plate, circular rings are respectively fixedly installed on the vertical tubes, elastic rubber tubes are respectively arranged on the inner circumferences of the vertical tubes, one end of the elastic rubber tubes is respectively fixedly installed on the second rotating plate, and the other end of the elastic rubber tubes is respectively fixedly installed on the circular rings.

[0006] As described above, a cell separation device for cell research, the limiting device includes a sliding sleeve, a plurality of sliding sleeves are provided and correspond one to one with the vertical tubes, the sliding sleeves are fixedly mounted on the second rotating plate, the inner circumference of the sliding sleeves are slidably mounted with plug rods, the plug rods are connected to the corresponding sliding sleeves by springs, and a plurality of slots are provided on the vertical tubes corresponding to the plug rods, and the plug rods can be plugged into and matched with the corresponding slots.

[0007] In the cell separation device for cell research as described above, a baffle is fixedly mounted on one end of the insertion rod away from the vertical tube.

[0008] In the cell separation device for cell research as described above, the outer periphery of the vertical shaft is provided with threads and a nut is installed in cooperation with the threads. The nut is rotatably mounted on the second rotating plate through a bearing, and the second rotating plate is slidably mounted on the vertical shaft.

[0009] In the cell separation device for cell research as described above, a handle is fixedly mounted on the periphery of the nut.

[0010] In the cell separation device for cell research as described above, a plurality of heat dissipation holes are provided on the side wall at the lower end of the cylinder.

[0011] The advantages of the utility model are: the utility model has a simple structure and an ingenious conception. When the diameter of the test tube is smaller than the diameter of the placement hole, the vertical tube is rotated, and the rotation of the vertical tube drives the upper end of the elastic rubber tube to rotate, while the lower end of the elastic rubber tube does not rotate. The two ends of the elastic rubber tube rotate relatively, and the middle is tightened inward. The middle of the elastic rubber tube is tightly attached to the test tube, thereby fixing the test tube. The fixation is stable, can meet market demand, and is suitable for promotion. When using the utility model, the top cover is rotated to open and the test tube is placed in the corresponding placement hole and placement groove. If the diameter of the test tube is smaller than the diameter of the placement hole, the limit of the vertical tube by the limit device is released, and then the vertical tube is rotated. The rotation of the vertical tube drives the corresponding circular ring and the upper end of the elastic rubber tube to rotate. Since the lower end of the elastic rubber tube is fixed on the second rotating plate and does not rotate, the elastic rubber tube can wrap and fix the test tube. After the vertical tube is fixed, the vertical tube is limited by the limit device to prevent the vertical tube from rotating at will. The top cover is rotated to close, and then the driving motor is started. The output shaft of the driving motor rotates to drive the vertical axis, the first rotating plate, the second rotating plate and the test tube fixed on the first rotating plate and the second rotating plate to rotate synchronously, and the centrifugal force generated by the rotation is used to separate the cells. BRIEF DESCRIPTION OF THE DRAWINGS

[0012] In order to more clearly illustrate the embodiments of the utility model or the technical solutions in the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are some embodiments of the utility model. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative labor.

[0013] Figure 1 It is a structural schematic diagram of the utility model; Figure 2 yes Figure 1 A partial enlarged view of Ⅰ.

[0014] Figure numerals: 1. cylinder, 2. top cover, 3. partition, 4. driving motor, 5. vertical axis, 6. first rotating plate, 7. placement groove, 8. second rotating plate, 9. placement hole, 10. vertical tube, 11. ring, 12. elastic rubber tube, 20. sliding sleeve, 21. plug rod, 22. spring, 23. slot, 30. baffle, 40. nut, 41. through hole, 42. slider, 43. slide groove, 50. handle, 60. heat dissipation hole. DETAILED DESCRIPTION

[0015] In order to make the purpose, technical solution and advantages of the embodiment of the utility model clearer, the technical solution in the embodiment of the utility model will be clearly and completely described below in conjunction with the drawings in the embodiment of the utility model. Obviously, the described embodiment is a part of the embodiment of the utility model, not all of the embodiments. Based on the embodiment of the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0016] A cell separation device for cell research, such as Figure 1 , 2As shown, it includes a cylinder 1, the top of the cylinder 1 is open and a top cover 2 is rotatably installed, a partition 3 is fixedly installed in the cylinder 1, a driving motor 4 is provided below the partition 3, the driving motor 4 is fixedly installed on the cylinder 1, the output shaft of the driving motor 4 passes through the partition 3 and a vertical shaft 5 is fixedly installed, the output shaft of the driving motor 4 passes through the reserved hole on the partition 3, and is rotatably installed in the reserved hole through a sealed bearing, a first rotating plate 6 is fixedly installed on the vertical shaft 5, a plurality of placement grooves 7 are provided on the first rotating plate 6, and the plurality of placement grooves 7 are evenly distributed around the axis of the vertical shaft 5, a second rotating plate 8 is provided at the upper end of the vertical shaft 5, and the vertical shaft 5, the first rotating plate 6 and the second rotating plate 8 are coaxial A plurality of placement holes 9 are provided on the second rotating plate 8 corresponding to the placement grooves 7, and the characteristics are as follows: vertical tubes 10 are provided above the placement holes 9, and the vertical tubes 10 are rotatably mounted on the second rotating plate 8 through bearings, and a limiting device for limiting the arbitrary rotation of the vertical tubes 10 is provided on the second rotating plate 8, and circular rings 11 are fixedly mounted on the vertical tubes 10, and elastic rubber tubes 12 are provided on the inner circumferences of the vertical tubes 10, and one end of the elastic rubber tubes 12 is fixedly mounted on the second rotating plate 8, and the other end of the elastic rubber tubes 12 is fixedly mounted on the circular rings 11, and the placement holes 9 are coaxially arranged with the corresponding placement grooves 7, vertical tubes 10, circular rings 11 and elastic rubber tubes 12. The utility model has a simple structure and an ingenious design. When the diameter of the test tube is smaller than the diameter of the placement hole 9, the vertical tube 10 is rotated. The rotation of the vertical tube 10 drives the upper end of the elastic rubber tube 12 to rotate, and the lower end of the elastic rubber tube 12 does not rotate. The two ends of the elastic rubber tube 12 rotate relatively, and the middle is tightened inward. The middle of the elastic rubber tube 12 is tightly attached to the test tube, so that the test tube is fixed. The fixation is stable, can meet market demand, and is suitable for promotion. When using the utility model, the top cover 2 is rotated to open, and the test tube is placed in the corresponding placement hole 9 and placement groove 7. If the diameter of the test tube is smaller than the diameter of the placement hole 9, the limit device on the vertical tube 10 is released, and then the vertical tube 10 is rotated. The rotation of the vertical tube 10 drives the corresponding circular ring 11 and the upper end of the elastic rubber tube 12 to rotate. Since the lower end of the elastic rubber tube 12 is fixed on the second rotating plate 8 and does not rotate, the elastic rubber tube 12 can wrap and fix the test tube. After the vertical tube is fixed, the vertical tube 10 is limited by the limit device to prevent the vertical tube 10 from rotating at will. The top cover 2 is rotated to close, and then the drive motor 4 is started. The output shaft of the drive motor 4 rotates to drive the vertical shaft 5, the first rotating plate 6, the second rotating plate 8 and the test tubes fixed on the first rotating plate 6 and the second rotating plate 8 to rotate synchronously, and the centrifugal force generated by the rotation is used to separate the cells.

[0017] Specifically, as shown in the figure, the limiting device described in this embodiment includes a sliding sleeve 20. There are several sliding sleeves 20 and they correspond one to one with the vertical pipes 10. The sliding sleeves 20 are fixedly installed on the second rotating plate 8 respectively. The inner periphery of the sliding sleeve 20 is slidably installed with the plug rod 21. The plug rod 21 is connected to the corresponding sliding sleeve 20 through a spring 22. The spring 22 is sleeved on the outer periphery of the corresponding plug rod 21. One end of the spring 22 is fixedly connected to the outer periphery of the corresponding plug rod 21, and the other end of the spring 22 is fixedly connected to one side of the corresponding sliding sleeve 20. Several slots 23 are opened on the vertical pipe 10 corresponding to the plug rod 21, and the plug rod 21 can be plugged into and matched with the corresponding slots 23. When the vertical pipe 10 is to be rotated, the insertion rod 21 is pulled to move the insertion rod 21 in a direction away from the vertical pipe 10 and out of the corresponding slot 23. At this time, the spring 22 is extended, and then the vertical pipe 10 is rotated until the vertical pipe 10 is rotated to a suitable position. Then the insertion rod 21 is released, and under the elastic force of the spring 22 itself, the insertion rod 21 is plugged into and matched with the aligned slot 23 to limit the vertical pipe 10 again.

[0018] Specifically, as shown in the figure, the end of the plug rod 21 away from the vertical pipe 10 is fixedly installed with a baffle 30. Pulling the plug rod 21 through the baffle 30 is more convenient and labor-saving.

[0019] Further, as shown in the figure, the outer periphery of the vertical shaft 5 of this embodiment is provided with threads and the threads are matched to install the nut 40, the nut 40 is rotatably installed on the second rotating plate 8 through a bearing, the second rotating plate 8 is slidably installed on the vertical shaft 5, a through hole 41 is provided on the second rotating plate 8, a slider 42 is fixedly installed in the through hole 41, a slide groove 43 is provided on the outer periphery of the vertical shaft 5 corresponding to the slider 42, and the slider 42 is slidably installed in the slide groove 43. By twisting the nut 40, the nut 40 drives the second rotating plate 8 to move up and down along the vertical shaft 5, and the second rotating plate 8 drives the slider 42 to slide up and down along the slide groove 43, so that the distance between the first rotating plate 6 and the second rotating plate 8 can be adjusted, and can adapt to test tubes of different heights.

[0020] Further, as shown in the figure, the outer periphery of the screw nut 40 in this embodiment is fixedly mounted with a handle 50. It is more convenient and labor-saving to twist the screw nut 40 through the handle 50.

[0021] Furthermore, as shown in the figure, a plurality of heat dissipation holes 60 are provided on the side wall of the lower end of the cylinder 1 in this embodiment. The heat dissipation holes 60 facilitate heat dissipation of the drive motor 4 and prevent the drive motor 4 from being affected in use due to excessive temperature.

[0022] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the utility model, rather than to limit it. Although the utility model has been described in detail with reference to the aforementioned embodiments, those skilled in the art should understand that they can still modify the technical solutions described in the aforementioned embodiments, or make equivalent replacements for some of the technical features therein. However, these modifications or replacements do not deviate the essence of the corresponding technical solutions from the spirit and scope of the technical solutions of the various embodiments of the utility model.

Claims

1. A cell separation device for cell research, comprising a cylinder (1), the top of the cylinder (1) is open and a top cover (2) is rotatably installed, a partition (3) is fixedly installed in the cylinder (1), a driving motor (4) is provided below the partition (3), the driving motor (4) is fixedly installed on the cylinder (1), the output shaft of the driving motor (4) passes through the partition (3) and is fixedly installed on a vertical shaft (5), a first rotating plate (6) is fixedly installed on the vertical shaft (5), a plurality of placement grooves (7) are provided on the first rotating plate (6), a second rotating plate (8) is provided at the upper end of the vertical shaft (5), a plurality of placement holes (9) are provided on the second rotating plate (8) corresponding to the placement grooves (7), and the characteristics are: A vertical tube (10) is provided above the placement hole (9), and the vertical tube (10) is rotatably mounted on the second rotating plate (8) through a bearing. The second rotating plate (8) is provided with a limit device for limiting the random rotation of the vertical tube (10). A circular ring (11) is fixedly mounted on the vertical tube (10), and an elastic rubber tube (12) is provided on the inner circumference of the vertical tube (10), one end of the elastic rubber tube (12) is fixedly mounted on the second rotating plate (8), and the other end of the elastic rubber tube (12) is fixedly mounted on the circular ring (11).

2. A cell separation device for cell research according to claim 1, characterized in that: The limiting device comprises a sliding sleeve (20), wherein a plurality of sliding sleeves (20) are provided and correspond one to one with the vertical pipes (10), the sliding sleeves (20) are respectively fixedly mounted on the second rotating plate (8), the inner circumference of the sliding sleeves (20) is respectively slidably mounted with an insertion rod (21), the insertion rod (21) and the corresponding sliding sleeve (20) are connected via a spring (22), and a plurality of slots (23) are respectively provided on the vertical pipes (10) corresponding to the insertion rods (21), and the insertion rods (21) can be plugged and matched with the corresponding slots (23).

3. A cell separation device for cell research according to claim 2, characterized in that: A baffle plate (30) is fixedly mounted on one end of the insertion rod (21) away from the vertical pipe (10).

4. A cell separation device for cell research according to claim 1, characterized in that: The outer periphery of the vertical shaft (5) is provided with a thread and a nut (40) is installed in threaded cooperation. The nut (40) is rotatably installed on the second rotating plate (8) through a bearing. The second rotating plate (8) is slidably installed on the vertical shaft (5).

5. A cell separation device for cell research according to claim 4, characterized in that: A handle (50) is fixedly mounted on the outer periphery of the nut (40).

6. A cell separation device for cell research according to claim 1, characterized in that: A plurality of heat dissipation holes (60) are provided on the side wall at the lower end of the cylinder (1).

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