Hydrocolloid feeding device and micro-needle medicine film automatic packaging equipment

Abstract

The utility model provides a hydrocolloid feeding device and micro needle medicine film automatic packaging equipment, the hydrocolloid feeding device comprises an unreeling assembly, a first driving part, a second driving part, a first rotating shaft, a second rotating shaft, a second driving part and a third driving part, the unreeling assembly comprises an unreeling wheel and a first driving part, the first driving part drives the unreeling wheel to rotate along a first rotating direction, and the unreeling wheel is wound with a hydrocolloid roll; the hydrocolloid roll comprises a carrier film belt and a plurality of hydrocolloids which are adhered to the radial outer side surface of the carrier film belt at intervals; the winding assembly comprises a winding wheel and a second driving part for driving the winding wheel to rotate in the second rotating direction, and the winding wheel is fixedly connected with the free end of the carrier film belt; the positioning assembly is located between the unwinding assembly and the winding assembly, the positioning assembly comprises an assembling platform, a supporting table, an upstream film belt guiding assembly and a downstream film belt guiding assembly, and a first section of a carrier film belt unwound by the unwinding assembly is tensioned between the upstream film belt guiding assembly and the downstream film belt guiding assembly; the supporting table supports the lower side face of the first section. According to the hydrocolloid feeding device, automatic feeding of hydrocolloid for micro-needle medicine films is achieved.

Description

Technical Field

[0001] The utility model belongs to the technical field of design of automatic packaging equipment for micro-needle medicine films, and in particular relates to a hydrocolloid feeding device and automatic packaging equipment for micro-needle medicine films. Background Art

[0002] Dissolvable microneedles (drug films) are a new type of transdermal drug delivery technology with the advantages of high drug loading, high bioavailability, painless and non-invasive. In recent years, it has been widely used in the pharmaceutical field. In order to meet the production requirements of GMP (GOODMANUFACTURING PRACTICE), it is necessary to match the automated microneedle preparation production process and packaging equipment that meet production capacity, sterility assurance, and sustainable and stable operation. As a new preparation technology used in the pharmaceutical industry, the inventor found that there is no mature equipment compatible with it in the pharmaceutical equipment market. Based on this situation, the applicant proposed this utility model. Utility Model Content

[0003] Therefore, the utility model provides a hydrocolloid feeding device and microneedle medicine film automatic packaging equipment, which can solve the technical problem of the lack of corresponding microneedle medicine film automatic hydrocolloid feeding device in the prior art.

[0004] In order to solve the above problems, the utility model provides a hydrocolloid feeding device, comprising:

[0005] An unwinding assembly, comprising an unwinding wheel and a first driving member driving the unwinding wheel to rotate along a first rotation direction, wherein a hydrocolloid roll is wound around the unwinding wheel, and the hydrocolloid roll comprises a carrier film tape and a plurality of hydrocolloids adhered to the radial outer side of the carrier film tape at intervals;

[0006] A winding assembly, comprising a winding wheel and a second driving member driving the winding wheel to rotate along a second rotation direction, wherein the winding wheel is fixedly connected to the free end of the carrier film tape;

[0007] A positioning component is located between the unwinding component and the winding component, and the positioning component includes an assembly platform and a support table, an upstream film tape guide component and a downstream film tape guide component located on the assembly platform. The first section of the carrier film tape released by the unwinding component is tensioned between the upstream film tape guide component and the downstream film tape guide component, and the support table is supported on the lower side of the first section.

[0008] In some embodiments,

[0009] The height of the first section at the downstream side of the support platform becomes lower and lower.

[0010] In some embodiments,

[0011] The upstream film tape guiding assembly includes a first gravity roller and a first guide roller, wherein the first gravity roller is located between the first guide roller and the unwinding wheel, and the corner opening formed by the carrier film tape on the first gravity roller faces upward, while the corner opening formed by the carrier film tape on the first guide roller faces downward.

[0012] In some embodiments,

[0013] The carrier film tape led out by the first guide roller is in a horizontal state, and the horizontal height of the carrier film tape is equal to the horizontal height of the supporting plane of the supporting table.

[0014] In some embodiments,

[0015] The downstream film tape guiding assembly includes a second gravity roller and a second guide roller, wherein the second guide roller is located between the second gravity roller and the winding wheel, and the corner opening formed by the carrier film tape on the second gravity roller faces upward, while the corner opening formed by the carrier film tape on the second guide roller faces downward.

[0016] In some embodiments,

[0017] The assembly platform is also provided with a clamping and positioning component, the clamping and positioning component is located between the first guide roller and the support platform, and the clamping and positioning component includes a clamping claw.

[0018] In some embodiments,

[0019] The clamping and positioning components include two groups, and both groups of the clamping and positioning components are located between the first guide roller and the support platform.

[0020] In some embodiments,

[0021] An edge detection sensor is arranged between the clamping and positioning assembly on the downstream side and the support platform.

[0022] In some embodiments,

[0023] It also includes an assembly plate, and the unwinding assembly, the winding assembly and the positioning assembly are all assembled on the top surface of the assembly plate.

[0024] The utility model also provides a microneedle medicine film automated packaging device, including a hydrocolloid adsorption transfer mechanical arm and the above-mentioned hydrocolloid feeding device, wherein the hydrocolloid adsorption transfer mechanical arm has a suction head capable of peeling the hydrocolloid positioned at the downstream side edge of the support platform from the carrier film belt.

[0025] The utility model provides a hydrocolloid feeding device and a microneedle film automatic packaging device, which has the following beneficial effects:

[0026] The hydrocolloid roll wound on the unwinding wheel is transferred from the unwinding wheel to the winding wheel through the coordinated rotation of the unwinding wheel and the winding wheel. The support table is supported on the bottom side of the hydrocolloid roll. The hydrocolloid on the support table can be peeled off from the carrier film tape and transferred to the corresponding microneedle medicine film through the corresponding hydrocolloid transfer component to be combined with it, and the carrier film tape is wound and stored on the winding wheel, thereby realizing the automatic loading of hydrocolloid for the microneedle medicine film. BRIEF DESCRIPTION OF THE DRAWINGS

[0027] In order to more clearly illustrate the implementation of the utility model or the technical solution in the prior art, the following is a brief introduction to the drawings required for the implementation or the prior art description. The drawings described below are only exemplary, and for ordinary technicians in this field, other implementation drawings can be derived from the provided drawings without creative work.

[0028] Figure 1 It is a three-dimensional structural schematic diagram of the hydrocolloid feeding device of the utility model;

[0029] Figure 2 yes Figure 1 A partial enlarged view of point A in the middle.

[0030] The accompanying drawings are marked as follows:

[0031] 211, unwinding wheel; 212, first driving member; 221, reeling wheel; 222, second driving member; 231, assembly platform; 232, support table; 241, first gravity roller; 242, first guide roller; 251, second gravity roller; 252, second guide roller; 26, clamping claw; 27, edge detection sensor; 28, assembly plate; 200, hydrocolloid roll; 201, carrier film tape; 202, hydrocolloid. DETAILED DESCRIPTION

[0032] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. The following description of at least one exemplary embodiment is actually only illustrative and is by no means a limitation on the utility model and its application or use. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without making creative work are within the scope of protection of the utility model.

[0033] In the description of the present utility model, it needs to be understood that the directions or positional relationships indicated by directional words such as "front, back, up, down, left, right", "lateral, vertical, perpendicular, horizontal" and "top, bottom" are usually based on the directions or positional relationships shown in the drawings, and are only for the convenience of describing the present utility model and simplifying the description. Unless otherwise specified, these directional words do not indicate or imply that the device or element referred to must have a specific direction or be constructed and operated in a specific direction, and therefore cannot be understood as limiting the scope of protection of the present utility model; the directional words "inside and outside" refer to the inside and outside relative to the contours of each component itself.

[0034] For ease of description, spatially relative terms such as "above", "above", "on the upper surface of", "above", etc. may be used here to describe the spatial positional relationship between a device or feature and other devices or features as shown in the figure. It should be understood that spatially relative terms are intended to include different orientations of the device in use or operation in addition to the orientation described in the figure. For example, if the device in the accompanying drawings is inverted, the device described as "above other devices or structures" or "above other devices or structures" will be positioned as "below other devices or structures" or "below other devices or structures". Thus, the exemplary term "above" can include both "above" and "below". The device can also be positioned in other different ways (rotated 90 degrees or in other orientations), and the spatially relative descriptions used here are interpreted accordingly.

[0035] In addition, it should be noted that the use of terms such as "first" and "second" to limit components is only for the convenience of distinguishing the corresponding components. If not otherwise stated, the above terms have no special meaning and therefore cannot be understood as limiting the scope of protection of the utility model.

[0036] See also Figure 1 to Figure 2 As shown, according to an embodiment of the utility model, a hydrocolloid feeding device is provided, comprising:

[0037] The unwinding assembly (not labeled in the figure) includes an unwinding wheel 211 and a drive to drive the unwinding wheel 211 to rotate in a first direction (in Figure 1 The first driving member 212 rotates in the first direction (ie, clockwise), and the unwinding wheel 211 is wound with a hydrocolloid roll 200, the hydrocolloid roll 200 includes a carrier film tape 201 and a plurality of hydrocolloids 202 adhered to the radial outer surface of the carrier film tape 201 at intervals;

[0038] The winding assembly (not labeled in the figure) includes a winding wheel 221 and a second driving member 222 that drives the winding wheel 221 to rotate along a second rotation direction. The winding wheel 221 is fixedly connected to the free end of the carrier film tape 201. When the winding wheel 221 is driven to rotate, the carrier film tape 201 will be transferred from the unwinding wheel 211 to be wound on the winding wheel 221. According to the needs of actual conditions, the first rotation direction and the second rotation direction can be the same or different. In principle, the unwinding action of the unwinding wheel 211 and the winding action of the winding wheel 221 can be realized. The first driving member 212 and the second driving member 222 can specifically adopt corresponding rotary driving components such as rotary motors. In specific use, the first driving member 212 and the second driving member 222 can be respectively covered in corresponding isolation covers to prevent accidental installation accidents;

[0039] A positioning assembly (not labeled in the figure), the positioning assembly is located between the unwinding assembly and the winding assembly, the positioning assembly includes an assembly platform 231 and a support platform 232 located on the assembly platform 231, an upstream film tape guide assembly (not labeled in the figure) and a downstream film tape guide assembly (not labeled in the figure), the first section (not labeled in the figure) of the carrier film tape 201 released by the unwinding assembly is tensioned between the upstream film tape guide assembly and the downstream film tape guide assembly, the support platform 232 is supported on the lower side of the first section, forming a reliable support for the tensioned first section. The upstream and downstream of the upstream film tape guide assembly and the downstream film tape guide assembly are referenced to the direction in which the carrier film tape 201 moves from the unwinding wheel 211 to the winding wheel 221. The first rotation direction and the second rotation direction can be the same rotation direction or the opposite rotation direction according to actual needs, and the actual purpose of unwinding and winding is the control principle.

[0040] In this technical solution, the hydrocolloid roll 200 wound on the unwinding wheel 211 is transferred from the unwinding wheel 211 to the reeling wheel 221 through the coordinated rotation of the unwinding wheel 211 and the reeling wheel 221. The support table 232 is supported on the bottom side of the hydrocolloid roll 200. The hydrocolloid 202 on the support table 232 can be peeled off from the carrier film tape 201 and transferred to the corresponding microneedle drug film to be combined with it through the corresponding hydrocolloid transfer component (for example, the hydrocolloid adsorption transfer robot arm described later), and the carrier film tape 201 is wound and stored on the reel 221, thereby realizing the automatic loading of the hydrocolloid 202 for the microneedle drug film.

[0041] See Figure 1 and Figure 2As shown, in some embodiments, the height of the first section at the downstream side of the support platform 232 becomes lower and lower, that is, the first section is tilted and guided downward after moving out of the support surface area of ​​the support platform 232, so that the angle between the carrier film tape 201 and the support plane of the support platform 232 can be utilized to partially peel off the downstream side of the hydrocolloid 202 pasted on the carrier film tape 201 from the carrier film tape 201, which can facilitate further peeling of the hydrocolloid 202.

[0042] In some embodiments, the upstream film tape guiding assembly includes a first gravity roller 241 and a first guide roller 242, wherein the first gravity roller 241 is located between the first guide roller 242 and the unwinding wheel 211, and the wrap angle opening formed by the carrier film tape 201 on the first gravity roller 241 faces upward, and the wrap angle opening formed by the carrier film tape 201 on the first guide roller 242 faces downward. The first guide roller 242 and the first gravity roller 241 are both driven rollers, that is, they can rotate around their own axes following the movement of the carrier film tape 201. The first guide roller 242 is used for path planning of the upstream section of the carrier film tape 201, and it can be rotatably assembled on the assembly platform 231. The first gravity roller 241 relies on its own weight to apply force to the top surface of the upstream section of the aforementioned carrier film tape 201 to ensure the tension of the carrier film tape 201 during the movement (winding and unwinding) process. Specifically, the aforementioned first gravity roller 241 can move up and down in the height direction following the tensioning degree of the carrier film tape 201.

[0043] In a preferred embodiment, the carrier film tape 201 guided by the first guide roller 242 is in a horizontal state, and the horizontal height of the carrier film tape 201 is equal to the horizontal height of the support plane of the support table 232, that is, the carrier film tape 201 guided and sent out by the first guide roller 242 is in a horizontal state, and its horizontal height is consistent with the support plane so that the support table 232 can be reliably supported on the bottom side of the carrier film tape 201. When the hydrocolloid transfer component peels off the hydrocolloid 202, its downward force will not cause the carrier film tape 201 to deform downward, thereby improving the peeling smoothness of the hydrocolloid 202.

[0044] The downstream film tape guiding assembly includes a second gravity roller 251 and a second guide roller 252, wherein the second guide roller 252 is located between the second gravity roller 251 and the winding wheel 221, and the wrap angle opening formed by the carrier film tape 201 on the second gravity roller 251 faces upward, and the wrap angle opening formed by the carrier film tape 201 on the second guide roller 252 faces downward. The second guide roller 252 and the second gravity roller 251 are both driven rollers, that is, they can follow the movement of the carrier film tape 201 and rotate around their own axes. The second guide roller 252 is used for path planning of the upstream section of the carrier film tape 201, and it can be rotatably assembled on the assembly platform 231. The second gravity roller 251 relies on its own weight to apply force to the top surface of the upstream section of the aforementioned carrier film tape 201 to ensure the tension of the carrier film tape 201 during the movement (winding and unwinding) process. Specifically, the aforementioned second gravity roller 251 can follow the tension of the carrier film tape 201 and move up and down in the height direction.

[0045] In another preferred embodiment, a clamping and positioning component (not marked in the figure) is further provided on the assembly platform 231, and the clamping and positioning component is located between the first guide roller 242 and the support platform 232, and the clamping and positioning component includes a clamping claw 26. Specifically, the clamping claw 26 has two upper and lower parallel arrangements, and the hydrocolloid roll 200 passes through the gap between the two clamping claws 26. When a certain hydrocolloid 202 is in place, that is, reaches the preset operating position of the aforementioned hydrocolloid transfer component, the two clamping claws 26 are controlled to reliably clamp the hydrocolloid roll 200 therebetween. In a preferred embodiment, the clamping and positioning component includes two groups, and both groups of the clamping and positioning components are located between the first guide roller 242 and the support platform 232, so that the two clamping and positioning components can be used to achieve precise control of the feeding position of the hydrocolloid roll 200. As a specific embodiment, the aforementioned clamping and positioning assembly can be implemented by a cylinder clamp assembly currently available on the market, wherein the cylinder controls the two clamps 26 to move closer to each other to achieve clamping and move away from each other to achieve release of clamping, and the corresponding cylinder can be hidden and assembled within the assembly platform 231.

[0046] The clamping and positioning assembly (i.e. Figure 1 An edge detection sensor 27 is arranged between the clamping and positioning assembly on the right side of the support platform 232. The edge detection sensor 27 uses ultrasonic distance measurement. The position where the hydrocolloid 202 is located will be higher than the top surface of the carrier film belt 201. The edge detection sensor 27 detects the distance change and thus detects that the hydrocolloid 202 is in place, which can be fed back to the corresponding control component to control the aforementioned hydrocolloid transfer component to pick up and peel off the corresponding hydrocolloid 202 at the corresponding position.

[0047] In some embodiments, the hydrocolloid feeding device also includes an assembly plate 28, and the unwinding component, the winding component and the positioning component are all assembled on the top surface of the assembly plate 28. The relevant functional components are integrated into one through the assembly plate 28 to achieve modularization of the components, which is conducive to the precise determination of the position of the functional components and simplifies the assembly of the hydrocolloid feeding device and the corresponding microneedle film automated packaging equipment.

[0048] According to an embodiment of the utility model, there is also provided a microneedle drug film automated packaging device, comprising a hydrocolloid adsorption transfer robot arm and the above-mentioned hydrocolloid loading device, wherein the hydrocolloid adsorption transfer robot arm has a suction head capable of peeling the hydrocolloid 202 located at the downstream side edge of the support platform 232 from the carrier film belt 201. The above-mentioned suction head can specifically be a vacuum suction head.

[0049] It is easy for those skilled in the art to understand that, without conflict, the advantageous technical features of the above-mentioned methods can be freely combined and superimposed.

[0050] The above is only a preferred embodiment of the utility model, and is not intended to limit the utility model. Any modifications, equivalent replacements and improvements made within the spirit and principles of the utility model should be included in the protection scope of the utility model. The above is only a preferred implementation of the utility model. It should be pointed out that for ordinary technicians in this technical field, several improvements and variations can be made without departing from the technical principles of the utility model, and these improvements and variations should also be regarded as the protection scope of the utility model.

Claims

1. A hydrocolloid feeding device, characterized in that: include: An unwinding assembly comprises an unwinding wheel (211) and a first driving member (212) for driving the unwinding wheel (211) to rotate along a first rotation direction, a hydrocolloid roll (200) being wound around the unwinding wheel (211), the hydrocolloid roll (200) comprising a carrier film tape (201) and a plurality of hydrocolloids (202) adhered at intervals to the radial outer side of the carrier film tape (201); A winding assembly, comprising a winding wheel (221) and a second driving member (222) for driving the winding wheel (221) to rotate along a second rotation direction, wherein the winding wheel (221) is fixedly connected to a free end of the carrier film tape (201); A positioning component, wherein the positioning component is located between the unwinding component and the winding component, and the positioning component includes an assembly platform (231) and a support platform (232) located on the assembly platform (231), an upstream film tape guiding component and a downstream film tape guiding component. The first section of the carrier film tape (201) released by the unwinding component is tensioned between the upstream film tape guiding component and the downstream film tape guiding component, and the support platform (232) is supported on the lower side of the first section.

2. The hydrocolloid feeding device according to claim 1, characterized in that: The height of the first section located on the downstream side of the support platform (232) becomes lower and lower.

3. The hydrocolloid feeding device according to claim 1 or 2, characterized in that: The upstream film tape guiding assembly includes a first gravity roller (241) and a first guide roller (242), wherein the first gravity roller (241) is located between the first guide roller (242) and the unwinding wheel (211), and the wrap angle opening formed by the carrier film tape (201) on the first gravity roller (241) faces upward, and the wrap angle opening formed by the carrier film tape (201) on the first guide roller (242) faces downward.

4. The hydrocolloid feeding device according to claim 3, characterized in that: The carrier film tape (201) led out by the first guide roller (242) is in a horizontal state, and the horizontal height of the carrier film tape (201) is equal to the horizontal height of the supporting plane of the supporting platform (232).

5. The hydrocolloid feeding device according to claim 1 or 2, characterized in that: The downstream film tape guiding assembly includes a second gravity roller (251) and a second guide roller (252), wherein the second guide roller (252) is located between the second gravity roller (251) and the winding wheel (221), and the corner opening formed by the carrier film tape (201) on the second gravity roller (251) faces upward, and the corner opening formed by the carrier film tape (201) on the second guide roller (252) faces downward.

6. The hydrocolloid feeding device according to claim 3, characterized in that: The assembly platform (231) is also provided with a clamping and positioning component, the clamping and positioning component is located between the first guide roller (242) and the support platform (232), and the clamping and positioning component includes a clamping claw (26).

7. The hydrocolloid feeding device according to claim 6, characterized in that: The clamping and positioning components include two groups, and both groups of the clamping and positioning components are located between the first guide roller (242) and the support platform (232).

8. The hydrocolloid feeding device according to claim 7, characterized in that: An edge detection sensor (27) is provided between the clamping and positioning assembly on the downstream side and the support platform (232).

9. The hydrocolloid feeding device according to claim 1, characterized in that: It also includes an assembly plate (28), and the unwinding assembly, the winding assembly and the positioning assembly are all assembled on the top surface of the assembly plate (28).

10. An automated packaging device for microneedle drug films, characterized in that: It comprises a hydrocolloid adsorption transfer robot arm and the hydrocolloid loading device as described in any one of claims 1 to 9, wherein the hydrocolloid adsorption transfer robot arm has a suction head capable of peeling the hydrocolloid (202) positioned at the downstream side edge of the support platform (232) from the carrier film tape (201).

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