Medicament packaging assembly

By designing a drug packaging assembly including a cylinder, a piston and a check valve, the solid drug is mixed with a solvent to mix into a solution, suspension or gel, the problem of poor stability and large space in the drug packaging container is solved, and a solid form that is easy to store and transport is achieved, and it is easy for patients to dosage on their own.

CN222573116UActive Publication Date: 2025-03-07YOUCHANGDA (WUHAN) MEDICAL TECH CO LTD
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Patent Information

Application Number
CN202420252571.3
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-02-01
Publication Date
2025-03-07
Estimated Expiration
2034-02-01

AI Technical Summary

Technical Problem

In the prior art, the solution, suspension or gel dosage form directly stored in the drug packaging container has poor stability and occupies a large space, making it inconvenient for storage and transportation.

Method used

A drug packaging assembly is designed, including a cylinder, a piston and a check valve, which combines solid drugs into a solution, suspension or gel by mixing solid drugs with solvents, utilizing higher stability and smaller volume of drugs in solid form for easy storage and transportation, and enables simple drug delivery operations by pushing the piston.

Benefits of technology

It extends the effectiveness of the drug, reduces the complexity and cost of the formula, improves the safety of the drug, and facilitates the patient's own administration.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model provides a medicine packaging assembly which comprises a barrel-shaped piece, a feeding port and a discharging port which are communicated with each other are formed in the two ends of the barrel-shaped piece respectively, and a medicine storage cavity is formed in the barrel-shaped piece and used for containing solid medicine. A piston is arranged at the position, close to the feeding port, of the barrel-shaped piece, the piston is detachably connected with the barrel-shaped piece, the outer circumferential wall of the piston is matched with the inner circumferential wall of the barrel-shaped piece, and the piston is configured to be capable of sliding relative to the barrel-shaped piece. Before the medicine packaging assembly is used, the solid medicine and the solvent are mixed and blended into a solution for administration, and due to the fact that the stability of active ingredients of the dry solid medicine is good, a large number of stabilizers do not need to be added, and cost is saved; the solid medicine occupies a small volume and is convenient to store and transport; a solvent is directly guided into the medicine storage cavity through the feeding port, the administration medicine can be formed after simple shaking, operation is convenient, and self administration of a patient can be achieved.
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Description

Technical Field

[0001] The utility model relates to a medicine packaging component. Background Art

[0002] Certain drugs (such as oral drugs, drugs for cavity administration or Chinese medicine enema drugs, etc.) usually need to be prepared into solutions, suspensions or gels in advance in order to carry out the next step of drug administration. However, in the prior art, the dosage forms in the form of solutions, suspensions or gels prepared and stored in drug packaging containers usually have the defect of poor stability compared to solid preparations, whether in terms of physical stability, chemical stability or biological stability. In order to improve the stability of the solution, the commonly used practice is to add stabilizers such as antioxidants, thickeners, suspending agents, preservatives, etc. to the solution, which greatly increases the cost; on the other hand, the volume occupied by the solution, suspension or gel as a drug is relatively large, which is not convenient for storage and transportation. Utility Model Content

[0003] The technical problem to be solved by the utility model is to provide a drug packaging component in order to overcome the defects in the prior art that solutions, suspensions or gels as drugs are directly stored in drug packaging containers, the dosage forms of solutions, suspensions or gels have poor stability, occupy a relatively large space, and are inconvenient for storage and transportation.

[0004] The utility model solves the above technical problems through the following technical solutions:

[0005] The utility model provides a medicine packaging component, which comprises a cylindrical member, wherein two ends of the cylindrical member are respectively provided with a feed inlet and a discharge outlet which are connected to each other, and a medicine storage cavity is provided inside the cylindrical member, wherein the medicine storage cavity is used to place solid medicine;

[0006] The cylindrical member is provided with a piston near the feed port, the piston is detachably connected to the cylindrical member, and the outer peripheral wall of the piston matches the inner peripheral wall of the cylindrical member, and the piston is configured to be able to slide relative to the cylindrical member.

[0007] In the present solution, the above-mentioned structural form is adopted, and the solid medicine and the solvent are mixed and formulated into a solution, suspension or gel before use for administration. On the one hand, since the active ingredients in the form of dry solid particles or powders are usually more stable than those in the form of solutions, suspensions or gels, including physical stability, chemical stability and biological stability, they are resistant to storage and do not need to add a large amount of stabilizers, and the addition of preservatives, antioxidants, thickeners and suspending agents can be avoided, thereby extending the shelf life of the product, reducing the complexity of the formula, saving costs, and improving the safety of medication; on the other hand, the solid form of the drug occupies a small volume, which is convenient for storage and transportation; on the third hand, the solvent is directly introduced into the drug storage cavity through the feed port, and the drug for administration can be formed after simple shaking. The drug administration can be achieved by pushing the piston, which is convenient to operate and can enable patients to administer the drug by themselves.

[0008] Preferably, a one-way valve is installed in the middle of the piston, and the one-way valve is configured to be able to introduce the solvent into the medicine storage chamber.

[0009] In the present scheme, the above-mentioned structural form is adopted, and the introduction of the solvent can be directly achieved through the one-way valve installed at the feed port, without releasing the connection between the piston and the cylindrical member when introducing the solvent, which is easy to operate; and in the process of solvent introduction, it is avoided that the solvent flows out of the feed port and then destroys the drug administration environment; in the drug administration process, that is, in the process of pushing the piston to push the configured solution, suspension or gel out of the discharge port, it is avoided that the drug flows out of the feed port and affects the drug administration effect.

[0010] Preferably, the one-way valve comprises a liquid channel and an exhaust hole which are arranged at intervals, the liquid channel is configured so that the solvent enters the drug storage cavity through the liquid channel, and the exhaust hole is located on the outer peripheral side of the liquid channel.

[0011] In this solution, the above-mentioned structural form is adopted. When the solvent is introduced into the medicine storage cavity through the liquid channel, the gas in the medicine storage cavity can be discharged from the exhaust hole. The excess gas in the medicine storage cavity is discharged through the exhaust hole, which facilitates the smooth introduction of the solvent.

[0012] Preferably, the number of the exhaust hole is one;

[0013] Alternatively, there are multiple exhaust holes, and the multiple exhaust holes are evenly spaced around the circumference of the liquid channel.

[0014] Preferably, the drug packaging assembly further comprises a pushing member, wherein the pushing member is mounted on a side of the piston away from the discharge port, and the pushing member presses the piston toward the drug storage cavity.

[0015] In this solution, the above-mentioned structural form is adopted, and the piston is pushed toward the medicine storage chamber by the pushing member, so that the prepared solution, suspension or gel in the medicine storage chamber can be discharged from the discharge port, which is easy to operate.

[0016] Preferably, the pushing member is a push rod, a pump or a cylinder.

[0017] In this solution, the above-mentioned structural form is adopted, and the push rod, pump or cylinder is used as a pushing member to realize the linear movement of the piston, which has high reliability.

[0018] Preferably, the drug packaging assembly further comprises a first sealing member, which covers the feed port and is detachably connected to the feed port;

[0019] And / or, the drug packaging assembly further includes a second sealing member, which covers the discharge port and is detachably connected to the discharge port.

[0020] In this solution, the above-mentioned structural form is adopted. Before use, the feed port is sealed by the first seal and the discharge port is sealed by the second seal, which can prevent moisture and prevent microorganisms from entering the drug storage cavity to contaminate the drug and affect the drug effect.

[0021] Preferably, a connector is provided at the discharge port, and the connector is used to connect to a drug delivery pipeline.

[0022] In this solution, the above-mentioned structural form is adopted, and the medicine in the medicine storage cavity is transported to the drug administration pipeline through the connecting piece, which is convenient for adding medicine to the drug administration pipeline and facilitating drug administration.

[0023] Preferably, the connector is a Luer connector, a snap connector or a threaded connector.

[0024] In this solution, the above structural form is adopted, the connection effect is good and it is not easy to fall off.

[0025] Preferably, the wall surface of the cylindrical member is provided with scale lines;

[0026] And / or, the drug packaging assembly further comprises an outer packaging member, the outer packaging member is sealed, and the tubular member is built into the outer packaging member.

[0027] In this solution, the above-mentioned structural form is adopted, and scale lines are set on the wall of the cylindrical member to facilitate the determination of the amount of solvent used, achieve quantitative configuration, and thus achieve precise mixing. Before use, the cylindrical member is placed in the outer packaging member, which can prevent moisture, effectively control microbial contamination, and avoid affecting the drug effect.

[0028] The positive and progressive effects of the utility model are:

[0029] The drug packaging component in the utility model mixes solid drugs and solvents into solutions, suspensions or gels before use for drug administration. On the one hand, since the active ingredients in the form of dry solid particles or powders are usually more stable than those in the form of solutions, suspensions or gels, including physical stability, chemical stability and biological stability, they are resistant to storage and do not require the addition of a large amount of stabilizers, which can avoid the addition of preservatives, thereby extending the shelf life of the product, reducing the complexity of the formula, saving costs, and improving the safety of medication; on the other hand, the solid form of the drug occupies a smaller volume, which is convenient for storage and transportation; on the third hand, the solvent is directly introduced into the drug storage cavity through the feed port, and the drug for administration can be formed after simple shaking. The drug administration can be achieved by pushing the piston, which is convenient to operate and can enable patients to administer the drug by themselves. BRIEF DESCRIPTION OF THE DRAWINGS

[0030] Figure 1 This is a schematic structural diagram of a drug packaging assembly according to a preferred embodiment of the present utility model.

[0031] Figure 2 Another schematic structural diagram of a medicine packaging assembly according to a preferred embodiment of the present utility model.

[0032] Description of reference numerals:

[0033] Tubular part 1

[0034] Feed port 11

[0035] Discharge port 12

[0036] Medicine storage cavity 13

[0037] Piston 14

[0038] Check valve 15

[0039] Liquid channel 151

[0040] Exhaust hole 152

[0041] Connector 16 DETAILED DESCRIPTION

[0042] The present invention will be described more clearly and completely below by way of embodiments in conjunction with the accompanying drawings, but the present invention is not limited to the scope of the following embodiments.

[0043] Please combine Figure 1 and Figure 2For understanding, the utility model provides a drug packaging component, which includes a cylindrical member 1, wherein both ends of the cylindrical member 1 are respectively provided with a feed port 11 and a discharge port 12 which are interconnected, and the interior of the cylindrical member 1 is provided with a drug storage cavity 13, and the drug storage cavity 13 is used to place solid drugs; the cylindrical member 1 is provided with a piston 14 near the feed port 11, and the piston 14 is detachably connected to the cylindrical member 1, and the outer peripheral wall of the piston 14 matches the inner peripheral wall of the cylindrical member 1, and the piston 14 is configured to slide relative to the cylindrical member 1. The medicine storage cavity 13 of the cylindrical member 1 is filled with pre-prepared solid medicine, the connection between the piston 14 and the cylindrical member 1 is released, the feed port 11 is opened, the solvent (such as water) is introduced into the medicine storage cavity 13 through the feed port 11, and a medicine solution, suspension or gel is formed by simple shaking, the piston 14 is installed at the feed port 11, and the piston 14 is pushed to move in the direction close to the feed port 11, so that the solution, suspension or gel is released from the discharge port 12, and then the medicine can be administered to the administration site. The solid medicine can be a dry tablet, granule, powder, low-temperature dried product or extract paste, including a freeze-dried product.

[0044] In this embodiment, the solid medicine and the solvent are mixed and formulated into a solution, suspension or gel before use for administration. On the one hand, since the active ingredients in the form of dry solid particles or powders are usually more stable than those in the form of solutions, suspensions or gels, including physical stability, chemical stability and biological stability, they are durable in storage and do not require the addition of a large amount of stabilizers, and can avoid the addition of preservatives, antioxidants, thickeners and suspending agents, thereby extending the shelf life of the product, reducing the complexity of the formula, saving costs, and improving the safety of medication; on the other hand, the solid form of the drug occupies a smaller volume, which is convenient for storage and transportation; on the third hand, the solvent is directly introduced into the drug storage chamber 13 through the feed port 11, and the drug for administration can be formed after simple shaking, and the drug administration can be achieved by pushing the piston 14, which is convenient to operate and can enable patients to administer the drug by themselves.

[0045] In this embodiment, a one-way valve 15 is installed in the middle of the piston 14, and the one-way valve 15 is configured to be able to introduce the solvent into the drug storage chamber 13. The one-way valve 15 installed at the feed port 11 can directly introduce the solvent, without releasing the connection between the piston 14 and the cylindrical member 1 when introducing the solvent, which is convenient for operation; and in the process of introducing the solvent, it is prevented that the solvent flows out from the feed port 11, thereby destroying the drug administration environment; in the process of drug administration, that is, in the process of pushing the piston 14 to push the configured solution, suspension or gel out of the discharge port 12, it is prevented that the drug flows out from the feed port 11 and affects the drug administration effect. Specifically, the piston 14 is provided with a mounting hole, and the one-way valve 15 is mounted on the piston 14 through the mounting hole.

[0046] In this embodiment, if Figure 2As shown, the one-way valve 15 includes a liquid channel 151 and an exhaust hole 152 arranged at intervals, the liquid channel 151 is configured so that the solvent enters the medicine storage cavity 13 through the liquid channel 151, and the exhaust hole 152 is located at the outer peripheral side of the liquid channel 151. While the solvent is introduced into the medicine storage cavity 13 through the liquid channel 151, the gas in the medicine storage cavity 13 can be discharged from the exhaust hole 152, and the excess gas in the medicine storage cavity 13 is discharged through the exhaust hole 152, so that the solvent is smoothly introduced.

[0047] In this embodiment, there are multiple exhaust holes 152, which are evenly spaced around the circumference of the liquid channel 151, so that excess gas in the drug storage cavity 13 can be evenly discharged from the feed port 11. In other embodiments, there is only one exhaust hole 152.

[0048] In this embodiment, the drug packaging assembly further includes a pusher (not shown in the figure), which is mounted on the side of the piston 14 away from the discharge port 12, and the pusher presses the piston 14 toward the drug storage chamber 13. The piston 14 is pushed toward the drug storage chamber 13 by the pusher, so that the prepared solution, suspension or gel in the drug storage chamber 13 can be discharged from the discharge port 12, which is convenient for operation. Specifically, the pusher abuts against the side of the piston 14 away from the discharge port 12 and covers the exhaust hole 152, so as to prevent the solution in the drug storage chamber 13 from flowing out of the exhaust hole 152 during the process of pushing the piston 14.

[0049] In this embodiment, the pusher is a push rod, a pump or a cylinder. The push rod, pump or cylinder is used as a pusher to realize the linear movement of the piston 14, which has high reliability. Among them, when the push rod is used as the pusher, the push rod can be set as an integral part with the piston 14; the push rod can also be set separately from the piston 14. When medication is required, the push rod is abutted against the side wall of the piston 14 away from the discharge port 12, thereby pushing the piston 14 to move in the direction close to the discharge port 12. When a pump is used as a pusher, the pump is clamped with the piston 14, and the linear movement of the piston 14 is realized after the pump is started.

[0050] Of course, in other examples, as an alternative means, the pusher may adopt other devices for applying pressure to make the piston 14 output movement along the axis direction of the cylindrical member 1 .

[0051] In some embodiments, the drug packaging assembly further includes a first seal (not shown in the figure), which covers the feed port 11 and is detachably connected to the feed port 11. A detachable first seal is provided at the feed port 11, and before use, the feed port 11 is sealed by the first seal, which can prevent moisture, prevent microorganisms from entering the drug storage cavity 13 to contaminate the drug, and affect the effect of the drug. The drug packaging assembly further includes a second seal (not shown in the figure), which covers the discharge port 12 and is detachably connected to the discharge port 12. A detachable second seal is provided at the discharge port 12, and before use, the discharge port 12 is sealed by the second seal, which can prevent moisture, prevent microorganisms from entering the drug storage cavity 13 to contaminate the drug, and affect the effect of the drug.

[0052] In this embodiment, if Figure 1 As shown, a connector 16 is provided at the discharge port 12, and the connector 16 is used to connect the drug delivery pipeline. The drug in the drug storage cavity 13 is delivered to the drug delivery pipeline through the connector 16, which is convenient for adding the drug to the drug delivery pipeline and for drug delivery. Specifically, the connector 16 is a Luer connector, a snap connector or a threaded connector, which has a good connection effect and is not easy to fall off.

[0053] Specifically, a cover is provided at the discharge port 12, and a connector 16 is installed on the cover. The cover and the connector 16 can be installed as one piece, which is beneficial to improve assembly efficiency; or they can be detachably connected.

[0054] Specifically, the first sealing member covers the feed port 11 and is threadedly connected to the feed port 11 ; the second sealing member covers the discharge port 12 and is threadedly connected to the discharge port 12 , or the second sealing member covers the connector 16 and is threadedly connected to the connector 16 .

[0055] In other embodiments, the connector 16 may not be provided, and the drug is directly discharged from the discharge port 12 and directly contacts the administration site.

[0056] In some embodiments, the wall of the cylindrical member 1 is provided with scale lines (not shown in the figure). By providing scale lines on the wall of the cylindrical member 1, it is convenient to determine the amount of solvent used, achieve quantitative configuration, and thus achieve precise preparation. The drug packaging assembly also includes an outer packaging member, which is sealed and the cylindrical member 1 is built into the outer packaging member. Before use, the cylindrical member 1 is arranged in the outer packaging member, which can prevent moisture, effectively control microbial contamination, and avoid affecting the drug effect.

[0057] In this embodiment, the piston 14 is made of an elastic material, such as synthetic rubber, and the solvent can be directly inserted into the piston 14 through the syringe needle to extend into the medicine storage cavity 13 to achieve the introduction of the solvent, which is convenient for operation.

[0058] In the present embodiment, the material of the tubular member 1 is glass or a transparent polymer material, such as polyolefin, COC / COP (cycloolefin polymer), polyurethane, polyester, polystyrene or ABS plastic, which has good mechanical properties. Aseptic process can be implemented, such as irradiation or ultraviolet light sterilization process, to effectively control the contamination of microorganisms during the shelf life of the product. Of course, in other embodiments, the material of the tubular member 1 can be selected from other current drug packaging materials.

[0059] The solid medicine in the medicine packaging component in this embodiment can be traditional Chinese medicine, chemical medicine, microbial preparation or biological preparation, preferably a medicine for anorectal and gynecological system diseases to achieve cavity administration.

[0060] In the specific implementation, the outer packaging is removed, the cylindrical member 1 is taken out, the first sealing member installed at the feed port 11 is removed, and the solvent is pushed into the one-way valve 15 through a syringe or other drug storage device, so that the solvent can be introduced into the drug storage cavity 13, and the solvent can be mixed with the solid drug by simple shaking to form a solution, suspension or gel to be used. The second sealing member installed at the discharge port 12 is removed, the drug delivery pipeline is connected with the connecting member 16, and the pusher is abutted against the piston 14 and pushes the piston 14 to move in the direction close to the discharge port 12, so that the solution, suspension or gel prepared in the drug storage cavity 13 is delivered to the drug delivery pipeline through the discharge port 12, so as to realize the combination of drug packaging and drug delivery device, and avoid the drug transfer process.

[0061] Although the specific implementations of the utility model are described above, those skilled in the art should understand that this is only an example, and the protection scope of the utility model is defined by the attached claims. Those skilled in the art can make various changes or modifications to these implementations without departing from the principle and essence of the utility model, but these changes and modifications fall within the protection scope of the utility model.

Claims

1. A drug packaging assembly, characterized in that: The drug packaging assembly comprises a cylindrical member, wherein two ends of the cylindrical member are respectively provided with a feed inlet and a discharge outlet which are interconnected, and a drug storage cavity is provided inside the cylindrical member, wherein the drug storage cavity is used to place solid drugs; The cylindrical member is provided with a piston near the feed inlet, the piston is detachably connected to the cylindrical member, and the outer peripheral wall of the piston matches the inner peripheral wall of the cylindrical member, and the piston is configured to be able to slide relative to the cylindrical member; A one-way valve is installed in the middle of the piston, and the one-way valve is configured to be able to introduce the solvent into the medicine storage cavity.

2. The drug packaging assembly according to claim 1, characterized in that: The one-way valve comprises a liquid channel and an exhaust hole which are arranged at intervals, wherein the liquid channel is configured so that the solvent enters the drug storage cavity through the liquid channel, and the exhaust hole is located at the outer peripheral side of the liquid channel.

3. The drug packaging assembly according to claim 2, characterized in that: The number of the exhaust hole is one; Alternatively, there are multiple exhaust holes, and the multiple exhaust holes are evenly spaced around the circumference of the liquid channel.

4. The drug packaging assembly according to claim 1, characterized in that: The medicine packaging assembly further comprises a pushing member, which is installed on a side of the piston away from the discharge port, and the pushing member presses the piston toward the medicine storage cavity.

5. The drug packaging assembly according to claim 4, characterized in that: The pushing member is a push rod, a pump or a cylinder.

6. The drug packaging assembly according to claim 1, characterized in that: The drug packaging assembly further comprises a first sealing member, which covers the feed opening and is detachably connected to the feed opening; And / or, the drug packaging assembly further includes a second sealing member, which covers the discharge port and is detachably connected to the discharge port.

7. The drug packaging assembly according to claim 1, characterized in that: A connecting piece is provided at the discharge port, and the connecting piece is used to connect the drug delivery pipeline.

8. The drug packaging assembly according to claim 7, characterized in that: The connecting piece is a Luer connector, a snap connector or a threaded connector.

9. The drug packaging assembly according to claim 1, characterized in that: The wall surface of the cylindrical member is provided with scale lines; And / or, the drug packaging assembly further comprises an outer packaging member, the outer packaging member is sealed, and the tubular member is built into the outer packaging member.