Drug resistance detection plate

Abstract

The utility model relates to a drug resistance detection plate which comprises a frame body and a cover body, a plurality of sample grooves which are arranged in rows are formed in the top surface of the frame body; the lower part of the sample groove is hemispherical, the upper part of the sample groove is a cylinder with an upper opening and a lower opening, and the upper opening of the sample groove protrudes to form an annular convex ring; the bottom of the sample groove is higher than the bottom surface of the frame body; the outer edge of the frame body sinks to form a cover table; the cover body covers the cover table on the frame body; the edge of the top face of the frame body protrudes upwards to form a circle of flange. The flange is attached to the inner top face of the cover body. The drug resistance detection plate disclosed by the utility model is good in sealing performance, liquid in the sample grooves is not easy to spill out, the sealing performance and the isolation performance among the sample grooves are good, samples in the sample grooves are not easy to spill out, and cross infection or cross contamination of experiments is avoided, so that the accuracy of experimental results is ensured.

Description

Technical Field

[0001] The utility model relates to the technical field of experimental instruments, in particular to a drug resistance detection board. Background Art

[0002] The drug resistance test panel is a tool used to detect the drug resistance of pathogens or tumor cells. Through the drug resistance test panel, it is possible to determine which antibiotics, antiviral drugs or chemotherapy drugs the pathogens or tumor cells are sensitive to, thereby guiding clinical medication and improving treatment effects.

[0003] There are many types of drug resistance test panels, such as drug sensitivity panels for bacterial resistance testing and specific test panels for tumor cell resistance testing.

[0004] Drug resistance test plates are classified according to the number of wells. The most commonly used is a 96-well plate with eight rows and sixteen lines. The 96-well plate is mainly used for experiments such as microbial culture, cell culture, and drug screening. This plate has 96 independent small wells, and each well can be independently operated for experimental operations. It is very suitable for parallel processing of a large number of samples to improve experimental efficiency.

[0005] In the experiment, various operations can be performed in the 96-well plate according to specific needs, such as inoculating microorganisms, culturing cells, adding drugs, etc. By observing and analyzing the experimental results in each well, a large amount of data can be quickly obtained, and then an in-depth study of the experimental object can be carried out.

[0006] The existing problems of drug resistance test plates are: 1. The sealing and isolation between each sample slot are not done well, resulting in cross-infection or mutual contamination in the experiment, thus causing inaccurate experimental results; 2. The samples in the sample slots are easy to spill; 3. The entire drug resistance test plate has poor sealing and is prone to leakage; 4. After opening and closing the cover, the position change after the cover is rotated 180 degrees will cause cross-contamination between samples.

[0007] Therefore, a drug resistance detection board is designed to solve the above problems. Summary of the invention

[0008] In order to overcome the above shortcomings, the utility model provides a drug resistance detection board, including a frame and a cover;

[0009] The top surface of the frame is provided with a plurality of sample slots arranged in rows; the lower portion of the sample slots is hemispherical, and the upper portion is a cylindrical tube with upper and lower openings; the upper opening of the sample slots is raised to form an annular convex ring; the bottom of the sample slots is higher than the height of the bottom surface of the frame;

[0010] The outer edge of the frame body is sunken to form a cover platform; the cover body covers the cover platform on the frame body; the edge of the top surface of the frame body protrudes upward to form a circle of flange; the flange is in contact with the inner top surface of the cover body;

[0011] A downwardly protruding cover ring is provided at the inner bottom of the cover body corresponding to the sample slots one by one. The diameter of the cover ring is larger than the diameter of the protruding ring. The cover ring and the protruding ring are adapted to each other. The cover ring is buckled outside the protruding ring to seal each sample slot.

[0012] Preferably, in a top view, the top surface of the frame body and the upper left corner of the cover body are both provided with triangular cutouts that correspond to each other up and down.

[0013] Preferably, the bottom surface of the frame is provided with a plurality of reinforcing ribs, and the reinforcing ribs connect the inner edge of the side edge of the bottom surface of the frame and the outer side of the spherical bottom surface of the sample groove.

[0014] Preferably, a square groove is provided on one side of the top surface of the frame as a label column for holding labels.

[0015] Preferably, one end of each row of sample slots arranged in rows is sorted by capital letters; one end of each row of sample slots arranged in rows is sorted by Arabic numerals.

[0016] Preferably, a unique mark is provided next to each sample slot.

[0017] Preferably, the frame and the cover are made of optically transparent pure polystyrene.

[0018] The beneficial effects of the utility model are:

[0019] The drug resistance detection plate described in the utility model has good sealing performance, and the liquid in the sample slot is not easy to spill out. Each sample slot has good sealing performance and good isolation performance, and the sample in the sample slot will not spill out, thereby avoiding cross infection or mutual contamination in experiments, thereby ensuring the accuracy of experimental results. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] Figure 1 It is a three-dimensional diagram of the utility model;

[0021] Figure 2 is a perspective view of the utility model;

[0022] Figure 3 It is the front view of the utility model;

[0023] Figure 4 A three-dimensional diagram of the frame;

[0024] Figure 5 is a perspective view of the frame;

[0025] Figure 6 This is a three-dimensional diagram of the frame (inverted);

[0026] Figure 7 is a top view of the frame;

[0027] Figure 8 It is a bottom view of the frame;

[0028] Fig. 9 Three-dimensional cover Figure 1 ;

[0029] Fig.10 Three-dimensional cover Figure 2 ;

[0030] Fig.11 is a bottom view of the cover;

[0031] in:

[0032] 1-frame; 2-cover; 3-sample slot; 4-label column; 5-flange; 6-reinforcement rib; 7-cover ring; DETAILED DESCRIPTION

[0033] The following is a detailed description of the embodiments of the present invention with reference to the accompanying drawings.

[0034] Example

[0035] like Figure 1-3 As shown, a drug resistance detection plate comprises a frame 1 and a cover 2; a plurality of sample slots 3 arranged in rows are provided on the top surface of the frame 1; the lower portion of the sample slot 3 is hemispherical, and the upper portion is a cylindrical tube with upper and lower openings, and the upper opening of the sample slot 3 is raised to form an annular convex ring; the bottom of the sample slot 3 is higher than the height of the bottom surface of the frame 1, so as to ensure that the sample slot 3 will not fit the experimental table;

[0036] like Figure 4 As shown, the outer edge of the frame 1 is sunken to form a cover platform; the cover 2 covers the cover platform on the frame 1; the edge of the top surface of the frame 1 protrudes upward to form a circle of flange 5; the flange 5 and the inner top surface of the cover 2 are in contact with each other to play a sealing role;

[0037] like Fig.10 and Fig.11 As shown, a downwardly protruding cover ring 7 is provided at a position corresponding one to one between the inner bottom of the cover body 2 and the sample slot 3, the diameter of the cover ring 7 is larger than the diameter of the protruding ring, the cover ring 7 and the protruding ring are adapted to each other, and the cover ring 7 is buckled outside the protruding ring for sealing each sample slot 3.

[0038] like Figure 7 and Fig.10 As shown, in a top view, the top surface of the frame 1 and the upper left corner of the cover 2 are both provided with triangular corners that correspond to each other, for positioning, to avoid the cover 2 rotating 180 degrees to change its position and then buckling on the frame 1 when taking or placing, causing contamination of the sample in the sample slot 3;

[0039] like Figure 6 As shown, the bottom surface of the frame body 1 is provided with a plurality of reinforcing ribs 6 , and the reinforcing ribs 6 connect the inner edge of the side edge of the bottom surface of the frame body 1 and the outer side of the spherical bottom surface of the sample slot 3 .

[0040] like Figure 5 As shown, a square groove is provided on one side of the top surface of the frame 1 as a label column 4 for holding labels.

[0041] like Figure 7 As shown, one end of each row of sample slots 3 arranged in rows is sorted by capital letters; one end of each row of sample slots 3 arranged in rows is sorted by Arabic numerals.

[0042] Each sample slot 3 is provided with a dedicated mark next to it.

[0043] The frame 1 and the cover 2 are made of optically transparent pure polystyrene.

[0044] Directions:

[0045] Add the sample into the sample slot 3, and cover the cover body 2 on the frame body 1; the convex ring of the sample slot 3 is matched with the cover ring 7 on the inner bottom of the cover body 2, and the cover ring 7 is buckled outside the convex ring to seal each sample slot 3 to prevent the sample in the sample slot 3 from spilling;

[0046] The flange 5 fits the inner top surface of the cover 2 to seal the entire test plate.

[0047] The top surface of the frame 1 and the upper left corner of the cover 2 are both provided with triangular notches that correspond to each other up and down for positioning, so as to avoid cross contamination of samples in the sample slot 3 when the cover 2 is rotated 180 degrees to change its position and then buckled on the frame 1 when taking or placing.

[0048] In the description of the present invention, it should be understood that the terms "upper", "lower", "front", "back", "left", "right", "top", "bottom", "inside", "outside", etc., indicating directions or positional relationships, are based on the directions or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific direction, be constructed and operated in a specific direction, and therefore should not be understood as a limitation on the present invention.

[0049] In the description of the present invention, it should be noted that, unless otherwise clearly specified and limited, the terms "installation", "connection" and "connection" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection, or it can be an indirect connection through an intermediate medium, or it can be the internal communication of two components. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood by specific circumstances.

[0050] The above is only a preferred embodiment of the present invention. It should be pointed out that for ordinary technicians in this technical field, several improvements and modifications can be made without departing from the principle of the present invention. These improvements and modifications should also be regarded as the protection scope of the present invention.

Claims

1. A drug resistance detection board, characterized in that: It comprises a frame body ((1)) and a cover body ((2)); The top surface of the frame ((1)) is provided with a plurality of sample grooves ((3)) arranged in rows; the lower portion of the sample groove ((3)) is hemispherical, and the upper portion is a cylindrical tube with upper and lower openings; the upper opening of the sample groove ((3)) is raised to form an annular convex ring; the bottom of the sample groove ((3)) is higher than the bottom surface of the frame ((1)); The outer edge of the frame ((1)) is sunken to form a cover platform; the cover ((2)) covers the cover platform on the frame ((1)); the edge of the top surface of the frame ((1)) protrudes upward to form a circle of flange ((5)); the flange ((5)) and the inner top surface of the cover ((2)) are in contact with each other; A downwardly protruding cover ring ((7)) is provided at a position corresponding to the inner bottom of the cover body ((2)) and the sample slot ((3)), the diameter of the cover ring ((7)) is larger than the diameter of the protruding ring, the cover ring ((7)) and the protruding ring are matched, and the cover ring ((7)) is buckled outside the protruding ring to seal each sample slot ((3)); The top surface of the frame ((1)) and the upper left corner of the cover ((2)) are both provided with triangular cutouts that correspond to each other from top to bottom.

2. A drug resistance detection board according to claim 1, characterized in that: The bottom surface of the frame ((1)) is provided with a plurality of reinforcing ribs ((6)), and the reinforcing ribs ((6)) connect the inner edge of the side edge of the bottom surface of the frame ((1)) and the outer side of the spherical bottom surface of the sample tank ((3)).

3. A drug resistance detection board according to claim 2, characterized in that: A square groove is provided on one side of the top surface of the frame ((1)) as a label column ((4)) for holding labels.

4. A drug resistance detection board according to claim 3, characterized in that: The sample slots ((3)) are arranged in rows and one end of each row is sorted by capital letters; the sample slots ((3)) are arranged in rows and one end of each row is sorted by Arabic numerals.

5. A drug resistance detection board according to claim 4, characterized in that: Each sample slot ((3)) is provided with a unique mark next to it.

6. A drug resistance detection board according to claim 5, characterized in that: The frame ((1)) and the cover ((2)) are made of optically transparent pure polystyrene.

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