Drug intermediate drying equipment

Abstract

The utility model provides medicine intermediate drying equipment which comprises a drying cylinder, an inner cylinder is arranged on the inner side of the drying cylinder, a drying cavity is formed in the inner cylinder, a mounting disc is arranged at the top of the drying cavity, and a drying mechanism for drying medicine intermediates and an exhaust mechanism for assisting in drying are arranged at the top of the mounting disc. A mixing mechanism for mixing drug intermediates is arranged in the middle of the drying cavity; a first partition plate and a second partition plate are arranged on the top face of the mounting disc, an air inlet area is formed between the first partition plate and the second partition plate, and the drying mechanism is located in the air inlet area. According to the utility model, hot air is fed into the mixing mechanism through the drying mechanism, and the hot air can be fed into a drug intermediate in a multi-point manner in the mixing and stirring process of the drug intermediate by matching with a mixing vertical pipe, a mixing transverse pipe and a nozzle in the mixing mechanism, so that the hot air can uniformly and comprehensively flow and dry in the drug intermediate; and the drying equipment can be used for more comprehensively and fully drying the drug intermediates.

Description

Technical Field

[0001] The utility model relates to the technical field of pharmaceutical intermediate processing equipment, in particular to pharmaceutical intermediate drying equipment. Background Art

[0002] Drug intermediates are an important stage in the drug synthesis process. They refer to compounds produced in the intermediate steps of drug synthesis. These intermediates play a key role in drug synthesis and can be converted into final drugs through different chemical reactions.

[0003] In the production process of drug intermediates, drying of drug intermediates is an important step in the process of synthesizing drugs. It is usually carried out after the synthesis of intermediates. Drying can remove the solvent or moisture in the intermediates to improve their purity and stability. When drying drug intermediates, different drying methods are used according to the chemical properties of the drug intermediates. The most common one is airflow drying.

[0004] During the airflow drying process of drug intermediates, the drug intermediates are placed in a flowing airflow to dry under mild conditions. This method is suitable for intermediates with high solvent volatility. However, in the actual drying process of drug intermediates, it is found that the contact between the drug intermediates and the airflow is not comprehensive enough. Drying is performed according to the order in which the drug intermediates contact the airflow, which not only causes the drying of the drug intermediates to be slower, but also affects the accuracy of the staff's judgment on the degree of drying of the drug intermediates.

[0005] In summary, there is a need for a drying device that is convenient for uniformly and comprehensively drying pharmaceutical intermediates. Utility Model Content

[0006] In view of the deficiencies in the prior art, the utility model provides a drug intermediate drying device, which solves the problems mentioned in the background technology.

[0007] In order to achieve the above objectives, the present invention is implemented through the following technical solutions:

[0008] A drug intermediate drying device, comprising a drying cylinder, an inner cylinder is provided inside the drying cylinder, a drying chamber is formed inside the inner cylinder, a mounting plate is provided on the top of the drying chamber, a drying mechanism for drying the drug intermediate and an exhaust mechanism for auxiliary drying are provided on the top of the mounting plate, and a mixing mechanism for mixing the drug intermediate is provided in the middle of the drying chamber;

[0009] The top surface of the mounting plate is provided with a partition plate 1 and a partition plate 2, an air intake area is formed between the partition plate 1 and the partition plate 2, and the drying mechanism is located inside the air intake area;

[0010] The mixing mechanism includes a motor, a mixing vertical pipe, a mixing horizontal pipe and a nozzle. The motor is arranged at the bottom of the drying cylinder. A mixing vertical pipe is arranged at the output end of the motor. A mixing horizontal pipe is arranged on the outer side of the mixing vertical pipe. A plurality of nozzles are arranged on the side of the mixing horizontal pipe. There are multiple groups of mixing horizontal pipes and nozzles distributed in a circle on the outer side of the mixing vertical pipe. The top of the mixing vertical pipe is connected to the air intake area, and the mixing vertical pipe is connected to the inside of the mixing horizontal pipe.

[0011] Furthermore, the drying mechanism includes a mounting plate, an air pump and two heating rods. The mounting plate is arranged on the top surface of the mounting plate. The mounting plate is in an L-shaped structure. An air pump is arranged on the side of the mounting plate. The air inlet end of the air pump is located outside the drying cylinder. A heating rod is arranged on the top surface of the mounting plate. There are multiple heating rods distributed in an array on the top surface of the mounting plate.

[0012] Furthermore, the exhaust mechanism includes an air pump 2 and an air suction box. The air pump 2 is arranged on the top surface of the mounting plate, and the air suction box is located on the bottom surface of the mounting plate. The air suction box is connected to the air inlet end of the air pump 2, and the air outlet end of the air pump 2 is located outside the drying cylinder. The air suction box has an annular structure, and a plurality of air inlets are provided on the bottom surface of the air suction box.

[0013] Furthermore, a feed pipe is provided on the outer side of the top of the drying cylinder, a material guide plate is provided on the inner bottom of the inner cylinder, the material guide plate is in a conical structure, and a discharge pipe is provided at the bottom of the drying cylinder.

[0014] Furthermore, the mixing transverse tube is arranged at an angle on the side away from the nozzle, and the mixing transverse tube at the bottom is slidably fitted with the outer side of the material guide plate.

[0015] Furthermore, a temperature control cavity is formed between the drying cylinder and the inner cylinder, and a plurality of heating rods are arranged inside the temperature control cavity.

[0016] The utility model provides a drug intermediate drying device. Compared with the prior art, it has the following beneficial effects:

[0017] Hot air is sent into the mixing mechanism through the drying mechanism. In combination with the vertical mixing pipe, horizontal mixing pipe and nozzle in the mixing mechanism, hot air can be sent into the drug intermediate at multiple points during the mixing and stirring process of the drug intermediate, thereby enabling the hot air to flow evenly and completely inside the drug intermediate for drying, so that the drying equipment can dry the drug intermediate more comprehensively and fully. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] In order to more clearly illustrate the embodiments of the utility model or the technical solutions in the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the utility model. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.

[0019] Figure 1 A schematic structural diagram of a drug intermediate drying device of the utility model is shown;

[0020] Figure 2 The internal structure schematic diagram of the drying cylinder of the utility model is shown;

[0021] Figure 3 The schematic diagram of the structure of the mixing mechanism of the utility model is shown;

[0022] Figure 4 A schematic diagram of the cross-sectional structure of the overall side view of the utility model is shown;

[0023] As shown in the figure: 1. Drying cylinder; 11. Inner cylinder; 12. Temperature control chamber; 13. Feed pipe; 14. Guide plate; 15. Discharge pipe; 16. Heating rod 1; 2. Mixing mechanism; 21. Motor; 22. Mixing vertical pipe; 23. Mixing horizontal pipe; 24. Nozzle; 3. Mounting plate; 31. Partition 1; 32. Partition 2; 4. Drying mechanism; 41. Mounting plate; 42. Air pump 1; 43. Heating rod 2; 5. Exhaust mechanism; 51. Air pump 2; 52. Vacuum box. DETAILED DESCRIPTION

[0024] In order to make the purpose, technical solution and advantages of the embodiments of the utility model clearer, the technical solution in the embodiments of the utility model is described clearly and completely. Obviously, the described embodiments are part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments of the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0025] Embodiment 1:

[0026] In order to solve the technical problems in the background technology, the following drug intermediate drying equipment is provided:

[0027] Combination Figure 1-Figure 4 As shown, a drug intermediate drying device provided by the utility model comprises a drying cylinder 1, an inner cylinder 11 is arranged inside the drying cylinder 1, a drying chamber for placing drug intermediates is formed inside the inner cylinder 11, a mounting plate 3 is arranged on the top of the drying chamber, a drying mechanism 4 for drying drug intermediates and an exhaust mechanism 5 for auxiliary drying are arranged on the top of the mounting plate 3, the drying mechanism 4 can send hot air into the drying chamber to dry the drug intermediates, the exhaust mechanism 5 can exhaust the air in the drying chamber, a mixing mechanism 2 for mixing drug intermediates is arranged in the middle of the drying chamber, the mixing mechanism 2 can send hot air into the drug intermediates while mixing the drug intermediates, a partition 1 31 and a partition 2 32 are arranged on the top surface of the mounting plate 3, an air intake area is formed between the partition 1 31 and the partition 2 32, and the drying mechanism 4 is located inside the air intake area;

[0028] The mixing mechanism 2 includes a motor 21, a mixing vertical pipe 22, a mixing horizontal pipe 23 and a nozzle 24. The motor 21 is arranged at the bottom of the drying cylinder 1. The motor 21 can drive the mixing vertical pipe 22 and the mixing horizontal pipe 23 to rotate. The output end of the motor 21 is provided with a mixing vertical pipe 22, and the outer side of the mixing vertical pipe 22 is provided with a mixing horizontal pipe 23. A plurality of nozzles 24 are provided on the side of the mixing horizontal pipe 23. The mixing horizontal pipe 23 and the nozzles 24 are arranged in a ring array on the outer side of the mixing vertical pipe 22 in multiple groups. The top of the mixing vertical pipe 22 is connected to the air inlet area. The mixing vertical pipe 22 is connected to the inside of the mixing horizontal pipe 23. The mixing vertical pipe 22 connected to the air inlet area can deliver the hot air generated by the drying mechanism 4 into the inside of the drug intermediate at multiple points through the mixing horizontal pipe 23 and the nozzle 24, and cooperate with the mixing vertical pipe 22 and the mixing horizontal pipe 23 to mix and stir the drug intermediate, so that the hot air can flow and dry evenly and comprehensively inside the drug intermediate. In this way, the drying device can make the drug intermediate dry more comprehensively.

[0029] In this embodiment, the drying mechanism 4 includes a mounting plate 41, an air pump 42 and a heating rod 43. The mounting plate 41 is arranged on the top surface of the mounting plate 3. The mounting plate 41 is L-shaped. An air pump 42 is arranged on the side of the mounting plate 41. The air pump 42 can draw air into the air inlet area. The air inlet end of the air pump 42 is located outside the drying cylinder 1. A heating rod 43 is arranged on the top surface of the mounting plate 41. A plurality of heating rods 43 are arranged in an array on the top surface of the mounting plate 41. The heating rod 43 can heat the passing air. The L-shaped mounting plate 41 can guide the air sent in by the air pump 42 to contact with the heating rod 43.

[0030] In this embodiment, the exhaust mechanism 5 includes an air pump 51 and an exhaust box 52. The air pump 51 is arranged on the top surface of the mounting plate 3, and the exhaust box 52 is located on the bottom surface of the mounting plate 3. The exhaust box 52 is connected to the air inlet end of the air pump 51, and the air outlet end of the air pump 51 is located outside the drying cylinder 1. The exhaust box 52 has an annular structure, and a plurality of air inlets are provided on the bottom surface of the exhaust box 52. The air pump 51 arranged in the exhaust mechanism 5 can exhaust the air in the drying chamber after contact drying of the drug intermediates through the exhaust box 52, so as to facilitate the flow contact between the dry air and the drug intermediates.

[0031] Embodiment 2:

[0032] like Figure 1-Figure 4 As shown, based on the above embodiment, this embodiment further provides the following contents:

[0033] In order to facilitate the discharge of the drug intermediate from the drying device, the following design is provided in this embodiment:

[0034] A feed pipe 13 for adding drug intermediates is provided on the outer side of the top of the drying cylinder 1, a guide plate 14 is provided on the inner bottom of the inner cylinder 11, and the guide plate 14 is in a conical structure. A discharge pipe 15 for discharging drug intermediates is provided at the bottom of the drying cylinder 1. The guide plate 14 in a conical structure can assist the drug intermediates to be discharged from the discharge pipe 15.

[0035] In this embodiment, the mixing transverse tube 23 is inclined away from the nozzle 24, and the mixing transverse tube 23 at the bottom is fitted and slid with the outer side of the material guide plate 14. The mixing transverse tube 23 that fits and slides with the outer side of the material guide plate 14 can ensure that the drug intermediate at the bottom of the drying chamber can also contact with the hot air.

[0036] In this embodiment, a temperature control chamber 12 is formed between the drying cylinder 1 and the inner cylinder 11, and a plurality of heating rods 16 are arranged inside the temperature control chamber 12. The temperature of the drying chamber can be maintained by the plurality of heating rods 16 arranged inside the temperature control chamber 12, thereby ensuring that the drug intermediate is in a temperature state suitable for drying.

[0037] The working principle and use process of this utility model:

[0038] When using:

[0039] First, the drug intermediate to be dried is fed into the drying chamber formed in the inner cylinder 11 through the feed pipe 13, and then the motor 21 in the mixing mechanism 2 drives the mixing vertical pipe 22 and the mixing horizontal pipe 23 to rotate in the drying chamber to continuously mix and disperse the drug intermediate. At this time, the air pump 1 42 in the drying mechanism 4 feeds air into the air intake area, and the air entering the air intake area will contact and heat the heating rod 2 43. After the air is heated, the hot air will enter the mixing vertical pipe 22;

[0040] Then the hot air in the mixing vertical pipe 22 will pass through the inside of the mixing horizontal pipe 23 and be ejected by multiple nozzles 24. The hot air ejected by the nozzles 24 will be evenly distributed in the drug intermediate, so as to achieve the purpose of evenly drying the drug intermediate.

[0041] During the drying process:

[0042] When the hot air contacts the drug intermediate, the vacuum box 52 in the exhaust mechanism 5 can extract the air inside the drying chamber under the action of the air pump 51, so that the hot air contacts the drug intermediate and then is discharged from the drying device, so that the hot air and the drug intermediate can flow in contact. When the drug intermediate is dried, it can be discharged from the drying device through the discharge pipe 15.

[0043] It should be noted that, in this article, relational terms such as first and second, etc. are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Moreover, the terms "include", "comprise" or any other variants thereof are intended to cover non-exclusive inclusion, so that a process, method, article or device including a series of elements includes not only those elements, but also other elements not explicitly listed, or also includes elements inherent to such process, method, article or device. In the absence of further restrictions, the elements defined by the sentence "comprise a ..." do not exclude the existence of other identical elements in the process, method, article or device including the elements.

[0044] The above embodiments are only used to illustrate the technical solutions of the present invention, rather than to limit it. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art should understand that the technical solutions described in the aforementioned embodiments may still be modified, or some of the technical features may be replaced by equivalents. However, these modifications or replacements do not deviate the essence of the corresponding technical solutions from the spirit and scope of the technical solutions of the embodiments of the present invention.

Claims

1. A drug intermediate drying device, characterized in that: The invention comprises a drying cylinder (1), wherein an inner cylinder (11) is provided inside the drying cylinder (1), a drying chamber is formed inside the inner cylinder (11), a mounting plate (3) is provided at the top of the drying chamber, a drying mechanism (4) for drying drug intermediates and an exhaust mechanism (5) for assisting drying are provided at the top of the mounting plate (3), and a mixing mechanism (2) for mixing drug intermediates is provided in the middle of the drying chamber; The top surface of the mounting plate (3) is provided with a partition plate 1 (31) and a partition plate 2 (32), an air intake area is formed between the partition plate 1 (31) and the partition plate 2 (32), and the drying mechanism (4) is located inside the air intake area; The mixing mechanism (2) comprises a motor (21), a mixing vertical pipe (22), a mixing horizontal pipe (23) and a nozzle (24); the motor (21) is arranged at the bottom of the drying cylinder (1); the mixing vertical pipe (22) is arranged at the output end of the motor (21); the mixing horizontal pipe (23) is arranged outside the mixing vertical pipe (22); a plurality of nozzles (24) are arranged on the side of the mixing horizontal pipe (23); a plurality of groups of the mixing horizontal pipes (23) and the nozzles (24) are arranged in a ring outside the mixing vertical pipe (22); the top of the mixing vertical pipe (22) is communicated with the air inlet area; and the mixing vertical pipe (22) and the mixing horizontal pipe (23) are communicated with each other.

2. A drug intermediate drying device according to claim 1, characterized in that: The drying mechanism (4) comprises a mounting plate (41), an air pump (42) and a heating rod (43); the mounting plate (41) is arranged on the top surface of the mounting plate (3); the mounting plate (41) is in an L-shaped structure; an air pump (42) is arranged on the side surface of the mounting plate (41); an air inlet end of the air pump (42) is located outside the drying cylinder (1); a heating rod (43) is arranged on the top surface of the mounting plate (41); and a plurality of heating rods (43) are arranged in an array on the top surface of the mounting plate (41).

3. A drug intermediate drying device according to claim 1, characterized in that: The exhaust mechanism (5) comprises an air pump (51) and an air extraction box (52). The air pump (51) is arranged on the top surface of the mounting plate (3), and the air extraction box (52) is located on the bottom surface of the mounting plate (3). The air extraction box (52) is connected to the air inlet end of the air pump (51), and the air outlet end of the air pump (51) is located outside the drying cylinder (1). The air extraction box (52) is an annular structure, and a plurality of air inlets are provided on the bottom surface of the air extraction box (52).

4. A drug intermediate drying device according to claim 1, characterized in that: A feed pipe (13) is provided on the outside of the top of the drying cylinder (1), a guide plate (14) is provided on the bottom of the inner side of the inner cylinder (11), the guide plate (14) is in a conical structure, and a discharge pipe (15) is provided at the bottom of the drying cylinder (1).

5. A drug intermediate drying device according to claim 2, characterized in that: The mixing transverse tube (23) is arranged at an inclination on a side facing away from the nozzle (24), and the mixing transverse tube (23) at the bottom is slidably fitted with the outer side of the material guide plate (14).

6. A drug intermediate drying device according to claim 4, characterized in that: A temperature control chamber (12) is formed between the drying cylinder (1) and the inner cylinder (11), and a plurality of heating rods (16) are arranged inside the temperature control chamber (12).

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