Sample collection and detection device

Abstract

The utility model discloses a sample collection and detection device. The sample collection and detection device comprises a shell, a sampling head and a detection assembly, the sampling head is installed on the shell, the sampling head is provided with a capillary channel, and the capillary channel has a preset volume and is used for quantitatively collecting a sample. The detection assembly is arranged in the shell, and the detection assembly is matched with the sampling head and is used for receiving the sample and detecting the sample. According to the sample collection and detection device, the operation steps can be simplified, the risk that the blood sample is polluted can be reduced, the sample can be quantitatively collected, and therefore the accuracy of the detection result can be improved.

Description

Technical Field

[0001] The present application relates to the field of instant diagnosis, and in particular to a sample collection and detection device. Background Art

[0002] Blood has the characteristic of being able to be collected quickly through minimally invasive means. Using blood as a sample for disease detection and applying blood samples to immunochromatography has been developed and applied in many fields, including tumor marker detection, early prediction of cardiovascular disease, and infectious disease screening.

[0003] When using the detection device in the related art, it is necessary to pierce the skin and collect a blood sample in a sample collection container, mix the blood with a sample diluent, and then drip it into a designated position of a reagent card for detection.

[0004] However, the detection device in the related art is complicated to operate, and the risk of blood sample contamination is relatively high. In addition, the detection device in the related art cannot collect quantitative data, resulting in low accuracy of the detection result. Utility Model Content

[0005] The purpose of this application is to at least solve the problems in the related art that the detection device is cumbersome to operate, the risk of blood sample contamination is high, and quantitative collection is impossible. This purpose is achieved by:

[0006] The present application proposes a sample collection and detection device, comprising: a housing, a sampling head and a detection component. The sampling head is mounted on the housing, and the sampling head is provided with a capillary channel, and the capillary channel has a preset volume and is used to quantitatively collect samples. The detection component is arranged in the housing, and the detection component cooperates with the sampling head to receive the sample and detect the sample.

[0007] In the sample collection and detection device of the present application, the sample diluent can be received and detected by the detection component after being mixed with the sample, thereby simplifying the operating steps of the operator and reducing the difficulty of the operator's operation, so as to improve the detection efficiency. After the sample is collected, it is located in the capillary channel, thereby reducing the area of ​​contact between the sample and the external environment. After the sample is mixed with the sample diluent, it is received and detected by the detection component, thereby avoiding the exposure of the sample, thereby reducing the probability of the sample being contaminated. In addition, since the capillary channel has a preset volume, the capillary channel can quantitatively collect samples, thereby improving the accuracy of the detection structure. In addition, when the handheld shell is used for sampling, the position of the handheld shell is spaced from the sampling head, thereby further reducing the probability of the sample being contaminated.

[0008] In some embodiments, the sampling head includes a sampling portion, a filtering portion and a filter element. The sampling portion is provided with the capillary channel, and the capillary channel runs through the sampling portion. The filtering portion is connected to the sampling portion, and the filtering portion is installed on the housing and defines a filtering cavity connected to the capillary channel. The filter element is arranged in the filtering cavity and cooperates with the detection component.

[0009] In some embodiments, the sampling portion has a contact end surface suitable for contact sampling, the contact end surface is located on the side of the sampling portion away from the filtering portion, the contact end surface includes a contact surface and a transition surface connected to each other, at least part of the transition surface is located on the side of the contact surface close to the filtering portion, and one end of the capillary channel passes through the contact surface.

[0010] In some embodiments, the contact end surface is an arc-shaped surface; and / or the volume of the capillary channel is 1 μl-500 μl.

[0011] In some embodiments, the sample collection and detection device also includes a sample dilution tube, which defines a accommodating cavity with a first opening at one end, and the accommodating cavity is suitable for accommodating a sample diluent. The sampling head has a separated state and a connected state relative to the accommodating cavity. The sampling head in the separated state is separated from the accommodating cavity. When the sampling head is in the connected state, the sampling head is movably disposed in the accommodating cavity through the first opening. At least one of the sampling head and the shell is interference-connected with the inner wall of the sample dilution tube, so that the accommodating cavity is in an airtight state, so that when the sampling head is configured to move in a direction close to the bottom wall of the accommodating cavity, the sample dilution can be squeezed into the capillary channel.

[0012] In some embodiments, the accommodating chamber includes a first accommodating chamber and a second accommodating chamber, the first accommodating chamber has the first opening, the second accommodating chamber is located on a side of the first accommodating chamber away from the first opening, the second accommodating chamber is formed with a second opening, the volume of the second accommodating chamber is smaller than the volume of the first accommodating chamber, when the sampling head is in the connected state, in the length direction of the shell, the sampling head is movably arranged in the accommodating chamber between a first position and a second position, when the sampling head is in the first position, the second accommodating chamber is connected to the first accommodating chamber through the second opening, and the sampling head located in the second position closes the second opening so that the second accommodating chamber is in an airtight state, so that the sampling head is configured to squeeze the sample diluent into the capillary channel.

[0013] In some embodiments, the sample collection and detection device also includes a base, the base includes a first bottom shell and a second bottom shell, the second bottom shell includes a base portion and a mounting portion, the base portion is connected to the first bottom shell and defines a cavity, one end of the mounting portion is connected to the base portion, and the other end of the mounting portion abuts against the first bottom shell, the mounting portion is located in the cavity and defines the mounting cavity, the sample dilution tube is installed in the mounting cavity, the first bottom shell is provided with a third opening connected to the accommodating cavity; and / or, the accommodating cavity accommodates the sample diluent, the sample dilution tube is provided with a sealing sheet for closing the first opening, and the sealing sheet is configured to be destroyed by extrusion; and / or, the inner wall of the sample dilution tube is provided with a protrusion, and at least one of the sampling head and the shell is interference-connected with the protrusion.

[0014] In some embodiments, the shell defines a detection cavity, the sampling head is inserted into the shell and located in the detection cavity, the detection assembly includes a bracket and a test strip that cooperates with the sampling head, the bracket includes a frame, a first connecting part and a second connecting part, the frame can be detachably arranged in the detection cavity and defines a mounting groove, the first connecting part is connected to the frame and located in the mounting groove, the test strip is arranged in the mounting groove and connected to the first connecting part, and the second connecting part is located on the outer peripheral wall of the frame and connected to the frame.

[0015] In some embodiments, in the circumferential direction of the frame, the frame defines a plurality of the mounting grooves, each of the mounting grooves is provided with the first connecting portion, a plurality of the test strips are provided, and the plurality of test strips are correspondingly arranged in the plurality of the mounting grooves and connected to the first connecting portion.

[0016] In some embodiments, the housing is provided with a plurality of transparent windows, and the plurality of windows are arranged in a one-to-one correspondence with the plurality of test strips.

[0017] In some embodiments, the test strip includes laminated absorbent paper for absorbing water, a nitrocellulose membrane, a coupling pad including a labeled protein, and a sample pad for absorbing and pretreating the sample, and the shell is provided with a transparent window portion, which is located on a side of the test strip close to the nitrocellulose membrane.

[0018] In some embodiments, the sample collection and detection device also includes a tube plug connected to the frame, the tube plug can be detachably connected to the shell, and is arranged at one end of the detection cavity away from the sampling head. The tube plug is provided with a ventilation structure, a part of the ventilation structure is connected to the detection cavity, and another part of the ventilation structure is connected to the outside world, and the sampling head closes one end of the detection cavity. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] Various other advantages and benefits will become apparent to those of ordinary skill in the art by reading the detailed description of the preferred embodiments below. The accompanying drawings are only for the purpose of illustrating the preferred embodiments and are not to be considered as limiting the present application. In addition, the same reference numerals are used throughout the accompanying drawings to represent the same components. Among them:

[0020] Figure 1 A schematic diagram of a sample collection and detection device according to an embodiment of the present application;

[0021] Figure 2 A partial schematic diagram of a sample collection and detection device according to an embodiment of the present application;

[0022] Figure 3 An exploded view of a sample collection and detection device according to an embodiment of the present application;

[0023] Figure 4 An exploded view of a sampling head according to an embodiment of the present application;

[0024] Figure 5 A front view of a sampling head according to an embodiment of the present application;

[0025] Figure 6 A cross-sectional view of a partial structure of a sample collection and detection device according to an embodiment of the present application;

[0026] Figure 7 A schematic diagram of a sample dilution tube according to an embodiment of the present application;

[0027] Figure 8 A schematic diagram of a first bottom shell of an embodiment of the present application;

[0028] Fig. 9 A schematic diagram of another viewing angle of the first bottom shell of the embodiment of the present application;

[0029] Fig.10 A schematic diagram of a second bottom shell of an embodiment of the present application;

[0030] Fig.11 A schematic diagram of a pipe plug according to an embodiment of the present application;

[0031] Fig.12 A schematic diagram of a bracket according to an embodiment of the present application;

[0032] Fig.13 A partial cross-sectional view of a test strip according to an embodiment of the present application;

[0033] Fig.14 A schematic diagram of the cooperation between the base and the sample dilution tube of an embodiment of the present application;

[0034] Fig.15 Schematic diagrams of brackets of other embodiments of the present application;

[0035] Fig.16 Partial schematic diagram of sample collection and detection devices according to other embodiments of the present application.

[0036] The reference numerals in the accompanying drawings represent the following:

[0037] 100. Sample collection and testing device;

[0038] 1. Shell; 11. Detection chamber; 12. Window;

[0039] 2. Sampling head; 21. Sampling part; 211. Capillary channel; 22. Filter part; 221. Filter cavity; 222. Plate section; 23. Filter element; 24. Contact end surface; 241. Contact surface; 242. Transition surface;

[0040] 3. Detection component; 31. Bracket; 311. Frame; 3111. Mounting slot; 3112. Fourth opening; 312. First connection portion; 313. Second connection portion; 32. Test strip; 321. Nitrocellulose membrane; 3211. Quality control line; 3212. Detection line; 322. Absorbent paper; 323. Coupling pad; 324. Sample pad;

[0041] 4. Sample dilution tube; 41. Accommodation cavity; 411. First accommodation cavity; 4111. First opening; 412. Second accommodation cavity; 4121. Second opening; 42. Raised portion; 43. Positioning flange;

[0042] 5. base; 51. first bottom shell; 511. cavity; 512. third opening; 52. second bottom shell; 521. base portion; 522. mounting portion; 5221. mounting cavity; 5222. latching structure;

[0043] 6. Pipe plug; 61. First plug body; 62. Second plug body; 63. Ventilation structure; 631. Ventilation channel; 632. Air hole. DETAILED DESCRIPTION

[0044] The exemplary embodiments of the present application will be described in more detail below with reference to the accompanying drawings. Although the exemplary embodiments of the present application are shown in the accompanying drawings, it should be understood that the present application can be implemented in various forms and should not be limited by the embodiments described herein. On the contrary, these embodiments are provided in order to enable a more thorough understanding of the present application and to fully convey the scope of the present application to those skilled in the art.

[0045] Immunochromatography, also known as lateral flow immunochromatography, is a rapid detection technology based on antigen-antibody specific binding. Immunochromatography pre-couples known antigens or antibodies to a carrier, and uses capillary action to allow the sample to flow through the capture line on the carrier. If there are corresponding antibodies or antigens in the sample, the sample will react specifically with the antigen or antibody on the carrier and adsorb to the carrier. The color development or luminescence of the marker is used to detect whether the sample contains the substance to be tested and its content.

[0046] Blood has the characteristic of being able to be collected quickly through minimally invasive means. Using blood as a sample for disease detection and applying blood samples to immunochromatography has been developed and applied in many fields, including tumor marker detection, early prediction of cardiovascular disease, and infectious disease screening.

[0047] When using the detection device in the related art, it is necessary to pierce the skin and collect a blood sample in a sample collection container, mix the blood with a sample diluent, and then drip it into a designated position of a reagent card for detection.

[0048] It can be seen that the operation steps of the detection device in the related art are relatively complicated. Moreover, during the process of dripping the blood sample onto the test card, the blood sample is in an exposed state, resulting in a greater risk of contamination of the blood sample.

[0049] In addition, in the related art, blood is collected through a sampling tube, but the volume of the sampling tube in the related art is not compatible with the detection requirements of the detection device, resulting in the amount of sample added to the detection device being too high or too low, thereby affecting the detection result of the detection device, and further resulting in a low accuracy rate of the detection result.

[0050] In order to at least solve the problems in the related art that the detection device has complicated operation steps, a high risk of blood sample contamination, and cannot be quantitatively collected, the embodiment of the present application proposes a sample collection detection device 100, which can simplify the operation steps, reduce the risk of blood sample contamination, and can quantitatively collect samples, thereby improving the accuracy of the test results.

[0051] The sample collection and detection device 100 according to an embodiment of the present application is described below with reference to the accompanying drawings.

[0052] Combination Figure 1 , Figure 2 and Figure 3 As shown, the sample collection and detection device 100 of the embodiment of the present application includes a housing 1, a sampling head 2 and a detection component 3. The sampling head 2 is installed in the housing 1, and the sampling head 2 is provided with a capillary channel 211, and the capillary channel 211 has a preset volume for quantitatively collecting samples. The detection component 3 is arranged in the housing 1, and the detection component 3 cooperates with the sampling head 2 to receive and detect the sample.

[0053] Capillary phenomenon refers to the phenomenon that liquid rises in small pipes or pores. This process is caused by the interaction between the surface tension of the liquid and the solid surface. The surface tension of the liquid is caused by the cohesive force between the liquid molecules, and the surface tension of the liquid makes the liquid surface tend to shrink. When the liquid enters a small pipe, the interaction between the liquid and the solid (such as adhesion) will cause the liquid to form a curved surface in the pipe, thus producing capillary phenomenon.

[0054] The detection component 3 and the sampling head 2 may be matched so that the detection component 3 abuts against the sampling head 2 so that the detection component 3 can receive and detect the sample collected by the sampling head 2. The detection component 3 and the sampling head 2 may also be matched so that, when the detection component 3 can receive the sample collected by the sampling head 2, a certain distance is spaced between the detection component 3 and the sampling head 2 so that the detection component 3 can receive and detect the sample collected by the sampling head 2.

[0055] The sample collected by the capillary channel 211 may be fingertip blood or other parts of blood.

[0056] When sampling, the housing 1 is held and the sampling head 2 is brought into contact with the punctured skin, and a capillary phenomenon is generated in the capillary channel 211 to draw blood into the capillary channel 211. Since the capillary channel 211 has a preset volume, the capillary channel 211 can quantitatively collect samples and make the collected sample volume fit the detection requirements. After sampling is completed, the sampling head 2 is brought into contact with the sample diluent, so that the sample diluent enters the capillary channel 211, and then the sample diluent and the sample are mixed and received and detected by the detection component 3.

[0057] In the sample collection and detection device 100 of this embodiment, the sample diluent can be received and detected by the detection component 3 after being mixed with the sample, thereby simplifying the operating steps of the operator and reducing the operating difficulty of the operator, so as to improve the detection efficiency. After the sample is collected, it is located in the capillary channel 211, so that the area of ​​contact between the sample and the external environment can be reduced. After the sample is mixed with the sample diluent, it is received and detected by the detection component 3, so that the sample can be avoided from being exposed, thereby reducing the probability of the sample being contaminated. In addition, since the capillary channel 211 has a preset volume, the capillary channel 211 can quantitatively collect samples and make the collected sample volume adapt to the detection requirements, thereby improving the accuracy of the detection structure. In addition, when the handheld shell 1 is sampled, the position of the handheld shell 1 is spaced from the sampling head 2, so that the probability of the sample being contaminated can be further reduced.

[0058] In some embodiments, the volume of the capillary channel 211 is 1 μL (microliter)-500 μL. For example, the volume of the capillary channel 211 can be 50 μL, 100 μL, 150 μL, 200 μL, 250 μL, 300 μL, 350 μL, 400 μL, 450 μL, and so on.

[0059] By making the volume of the capillary channel 211 1 μL-500 μL, the sample volume collected by the capillary channel 211 can meet the detection requirements, and the capillary channel 211 can generate a capillary phenomenon.

[0060] Combination Figure 2 , Figure 4 and Figure 5 As shown, in some embodiments, the sampling head 2 includes a sampling portion 21, a filtering portion 22 and a filter element 23. The sampling portion 21 is provided with a capillary channel 211, and the capillary channel 211 runs through the sampling portion 21. The filtering portion 22 is connected to the sampling portion 21, and the filtering portion 22 is installed on the housing 1, and defines a filtering cavity 221 connected to the capillary channel 211. The filter element 23 is arranged in the filtering cavity 221 and cooperates with the detection component 3.

[0061] The capillary channel 211 penetrates the sampling portion 21 and is connected to the filter cavity 221. After the capillary channel 211 collects the sample, the sample diluent flushes the sample in the capillary channel 211 into the filter cavity 221 and into the filter element 23, where the sample diluent and the sample are mixed.

[0062] The filter element 23 can filter blood cells and other macromolecular substances not required for detection in the sample, and can adsorb substances that may interfere with the detection results. The filter element 23 can also slow down the flow speed of the sample to prevent the sample from splashing onto the detection component 3 too quickly, thereby avoiding affecting the detection results.

[0063] The filter element 23 and the detection component 3 may be matched so that the filter element 23 abuts against the detection component 3 so that the detection component 3 can receive the sample in the filter element 23 and perform detection. The filter element 23 and the detection component 3 may also be matched so that when the detection component 3 can receive the sample in the filter element 23, a certain distance is spaced between the detection component 3 and the filter element 23 so that the detection component 3 can receive the sample in the filter element 23 for detection.

[0064] like Figure 6 As shown, in some optional embodiments, the filter portion 22 is inserted into the housing 1, and the outer wall of the filter portion 22 and the inner wall of the housing 1 are interference-connected, so that the sampling head 2 can be more firmly installed on the housing 1.

[0065] Combination Figure 2 and Figure 6As shown, in the length direction of the housing 1 , the edge of the sampling portion 21 abuts against the end wall of the housing 1 to enable positioning, thereby making the sampling head 2 more accurately installed.

[0066] like Figure 6 As shown, as some examples, the length direction of the shell 1 is as shown by the arrow at c.

[0067] In some other optional embodiments, in the length direction of the shell 1, the end of the filter part 22 away from the sampling part 21 abuts against the end of the shell 1, and the filter part 22 and the shell 1 are snap-fitted via a snap-fit ​​structure.

[0068] like Figure 4 As shown, in some optional embodiments, the filter portion 22 includes a plurality of plate segments 222, and the plurality of plate segments 222 are sequentially connected end to end to enclose a filter cavity 221. In the length direction of the housing 1, the filter element 23 has a plurality of side surfaces, and the plurality of side surfaces of the filter element 23 correspond to the plurality of plate segments 222 one by one, and each side surface is attached to the inner wall surface of the corresponding plate segment 222.

[0069] Therefore, by one-to-one correspondence between multiple side surfaces of the filter element 23 and multiple plate segments 222, each side surface is fitted to the inner wall surface of the corresponding plate segment 222, which can increase the fit between the shape of the filter element 23 and the shape of the filter cavity 221, thereby reducing the gap between the filter element 23 and the inner wall of the filter portion 22, thereby increasing the filtering effect on the sample.

[0070] In other optional embodiments, the inner wall of the filter part 22 is an arc-shaped surface, the filter element 23 is a column, and the side of the filter element 23 fits the inner wall of the filter part 22. This can increase the fit between the shape of the filter element 23 and the shape of the filter cavity 221, thereby reducing the gap between the filter element 23 and the inner wall of the filter part 22, thereby increasing the filtering effect on the sample.

[0071] Specifically, the filter element 23 is provided with a plurality of filter holes to improve the filtering effect.

[0072] Furthermore, the radial size of the filter holes ranges from 0.1 microns to 1000 microns, so that the filter holes can be suitable for filtering requirements of various detection items.

[0073] like Figure 5 As shown, in some embodiments, the sampling portion 21 has a contact end surface 24 suitable for contact sampling, the contact end surface 24 is located on the side of the sampling portion 21 away from the filtering portion 22, the contact end surface 24 includes a contact surface 241 and a transition surface 242 that are interconnected, at least a portion of the transition surface 242 is located on the side of the contact surface 241 close to the filtering portion 22, and one end of the capillary channel 211 passes through the contact surface 241.

[0074] By locating at least a portion of the transition surface 242 on the side of the contact surface 241 close to the filter portion 22, when collecting the sample, the contact surface 241 mainly contacts the skin, so that the contact area between the sampling portion 21 and the skin can be reduced, thereby reducing the risk of wound infection and reducing the strange feeling of contact between the sampling portion 21 and the skin.

[0075] like Figure 5 As shown, in some embodiments, the contact end surface 24 is an arc-shaped surface.

[0076] By making the contact end surface 24 an arc-shaped surface, the tactile feeling of the contact end surface 24 contacting the skin during sampling can be improved, and the strange feeling of the sampling part 21 contacting the skin can be further reduced.

[0077] The filter element 23 can be made of a hydrophilic material or a hydrophobic material. A hydrophobic material refers to a material that has a repellent interaction with water. A hydrophilic material refers to a material that has a good affinity with water.

[0078] As some examples, the filter element 23 is made of hydrophobic material.

[0079] By making the filter element 23 a hydrophobic material, the sample content in the filter element 23 can be reduced to increase the filtering effect. By making the filter element 23 a hydrophobic material, the sample remaining in the filter element 23 due to the adsorption of the filter element 23 can also be reduced, thereby making the detection result more accurate.

[0080] In some embodiments, the sampling portion 21 is made of a hydrophilic material.

[0081] By making the sampling portion 21 made of a hydrophilic material, the speed of collecting samples through the capillary channel 211 can be increased, thereby improving the sampling efficiency.

[0082] In other embodiments, the sampling portion 21 is made of a universal material, and the inner wall of the capillary channel 211 is treated to be hydrophilic.

[0083] The universal material refers to a universal material suitable for manufacturing the sampling portion 21, such as a universal plastic. Before being subjected to a hydrophilic modification treatment, the universal material has no hydrophilicity or has poor hydrophilicity.

[0084] By subjecting the inner wall of the capillary channel 211 to hydrophilic modification, the inner wall of the capillary channel 211 is made hydrophilic, so as to increase the speed of collecting samples through the capillary channel 211 and thus improve the sampling efficiency.

[0085] In some embodiments, a hydrophilic layer is disposed in the capillary channel 211 , and the hydrophilic layer is adhered and fixed in the capillary channel 211 .

[0086] The hydrophilic layer refers to a material layer having good affinity for water. By providing the hydrophilic layer in the capillary channel 211 , the speed of collecting samples by the capillary channel 211 can be increased, thereby improving the sampling efficiency.

[0087] Combination Figure 6 and Figure 7 As shown, in some embodiments, the sample collection and detection device 100 further includes a sample dilution tube 4, which defines a receiving cavity 41 with a first opening 4111 formed at one end, and the receiving cavity 41 is suitable for receiving the sample diluent, and the sampling head 2 has a separation state and a connection state relative to the receiving cavity 41, and the sampling head 2 in the separation state is separated from the receiving cavity 41. As an example, when the sampling head 2 collects a sample, the sampling head 2 is in the separation state.

[0088] When the sampling head 2 is in a connected state, the sampling head 2 is movably disposed in the accommodating chamber 41 through the first opening 4111, and at least one of the sampling head 2 and the shell 1 is interference-connected with the inner wall of the sample diluent tube 4, so that the accommodating chamber 41 is in an airtight state, so that when the sampling head 2 is configured to move toward the bottom wall of the accommodating chamber 41, the sample diluent can be squeezed into the capillary channel 211.

[0089] The airtight state of the accommodating chamber 41 can be a partially airtight state, that is, the accommodating chamber 41 can have air leakage when the sample diluent can be pressed into the capillary channel 211. The airtight state of the accommodating chamber 41 can also be a completely airtight state, that is, the accommodating chamber 41 does not have air leakage.

[0090] The sampling head 2 is inserted into the accommodating chamber 41 through the first opening 4111, so that the sampling head 2 is in a connected state. At least one of the sampling head 2 and the housing 1 is in interference connection with the inner wall of the sample diluent tube 4, so that the accommodating chamber 41 is in an airtight state, and the housing 1 is pushed to move the sampling head 2 toward the bottom wall of the accommodating chamber 41, so that the gas in the accommodating chamber 41 is squeezed, and the squeezed gas presses the sample diluent into the capillary channel 211. Therefore, the sample diluent can be more easily pressed into the capillary channel 211 through this embodiment.

[0091] like Figure 6 As shown, as some examples, the flow direction of the sample diluent is shown by the arrows at a and b.

[0092] like Figure 6 As shown, in some optional embodiments, the outer peripheral wall of the shell 1 and the inner wall of the sample dilution tube 4 are interference-connected to make the accommodating chamber 41 in an airtight state.

[0093] In some other optional embodiments, the outer peripheral wall of the sampling head 2 is interference-connected with the inner wall of the sample dilution tube 4 so that the accommodating chamber 41 is in an airtight state.

[0094] In some other optional embodiments, the outer peripheral wall of the shell 1 and the outer peripheral wall of the sampling head 2 are both interference-connected with the inner wall of the sample dilution tube 4, so that the accommodating chamber 41 is in an airtight state.

[0095] like Figure 6 As shown, in some embodiments, the accommodating chamber 41 includes a first accommodating chamber 411 and a second accommodating chamber 412, the first accommodating chamber 411 has a first opening 4111, the second accommodating chamber 412 is located on the side of the first accommodating chamber 411 away from the first opening 4111, the second accommodating chamber 412 is formed with a second opening 4121, and the volume of the second accommodating chamber 412 is smaller than the volume of the first accommodating chamber 411.

[0096] When the sampling head 2 is in a connected state, the sampling head 2 is movably arranged in the accommodating cavity 41 between a first position and a second position in the length direction of the shell 1. When the sampling head 2 is in the first position, the second accommodating cavity 412 is connected to the first accommodating cavity 411 through the second opening 4121. The sampling head 2 located in the second position closes the second opening 4121 to make the second accommodating cavity 412 in an airtight state, so that the sampling head 2 is configured to be able to squeeze the sample diluent into the capillary channel 211.

[0097] The airtight state of the second accommodating chamber 412 can be a partially airtight state, that is, the second accommodating chamber 412 can have air leakage when the sample diluent can be pressed into the capillary channel 211. The airtight state of the second accommodating chamber 412 can also be a completely airtight state, that is, the second accommodating chamber 412 does not have air leakage.

[0098] When the sampling head 2 is located at the first position, the sampling head 2 is moved toward the bottom wall of the accommodating chamber 41 , so that the sample diluent in the first accommodating chamber 411 and the second accommodating chamber 412 can enter the capillary channel 211 .

[0099] When the sampling head 2 is located at the second position, the gas in the accommodating chamber 41 is pressed into the second accommodating chamber 412, and the sampling head 2 closes the second opening 4121. Since the volume of the second accommodating chamber 412 is smaller than that of the first accommodating chamber 411, the volume of the gas in the second accommodating chamber 412 accounts for a larger proportion. The gas in the second accommodating chamber 412 can squeeze the residual sample diluent, thereby forcing the residual sample diluent into the capillary channel 211.

[0100] Therefore, by providing the first accommodating chamber 411 and the second accommodating chamber 412 , the residual sample diluent can be reduced, thereby improving the utilization rate of the sample diluent.

[0101] Combination Figure 1 , Figure 8 , Fig. 9 , Fig.10 and Fig.14 As shown, in some embodiments, the sample collection and detection device 100 also includes a base 5, the base 5 includes a first bottom shell 51 and a second bottom shell 52, the second bottom shell 52 includes a base portion 521 and a mounting portion 522, the base portion 521 is connected to the first bottom shell 51 and defines a cavity 511.

[0102] One end of the mounting portion 522 is connected to the base portion 521, and the other end of the mounting portion 522 abuts against the first bottom shell 51. The mounting portion 522 is located in the mold cavity 511 and defines a mounting cavity 5221. The sample tube 4 is installed in the mounting cavity 5221. The first bottom shell 51 is provided with a third opening 512 connected to the accommodating cavity 41.

[0103] The first bottom shell 51 is provided with a receiving cavity 41 , and the receiving cavity 41 is communicated with the third opening 512 , so that the sampling head 2 can extend into the receiving cavity 41 through the third opening 512 , thereby making the structure of the first bottom shell 51 more reasonable.

[0104] The sample dilution tube 4 is arranged on the mounting portion 522. When the sampling head 2 is in the connected state, the sample dilution tube 4 can be fixed by fixing the base 5, so as to reduce the difficulty of fixing the sample dilution tube 4. For example, the base 5 can be fixed by placing the base portion 521 on the surface of a desktop or other object, and the housing 1 is pushed to move the sampling head 2 in the direction close to the bottom wall of the accommodating chamber 41, so that the gas in the accommodating chamber 41 is squeezed, and the squeezed gas compresses the sample diluent into the capillary channel 211. For another example, the base 5 can be fixed by holding the base portion 521, and the housing 1 is pushed to move the sampling head 2 in the direction close to the bottom wall of the accommodating chamber 41, so that the gas in the accommodating chamber 41 is squeezed, and the squeezed gas compresses the sample diluent into the capillary channel 211.

[0105] Therefore, by reducing the difficulty of fixing the sample diluent tube 4, the sampling head 2 is facilitated to move in the accommodating chamber 41, thereby reducing the difficulty of injecting the sample diluent into the capillary channel 211, so that the sample collection and detection device 100 of this embodiment is easier to operate.

[0106] Fixing the base 5 means limiting the displacement of the base 5 in at least one direction, so as to avoid the base 5 interfering with the movement of the sampling head 2 in the process of pushing the housing 1 to move the sampling head 2 toward the bottom wall of the accommodating chamber 41. Since the sample dilution tube 4 is mounted on the mounting portion 522, after the base 5 is fixed, in the process of pushing the housing 1 to move the sampling head 2 toward the bottom wall of the accommodating chamber 41, the sample dilution tube 4 can avoid interfering with the movement of the sampling head 2.

[0107] like Figure 1As shown, when the sampling head 2 is in a connected state, the housing 1 , the sampling head 2 and the detection component 3 can be supported by the base 5 , so that the sample collection and detection device 100 of this embodiment can be placed and stored.

[0108] The base 5 has a relatively large volume and a relatively small weight by defining a cavity 511 between the base portion 521 and the first bottom shell 51. The base 5 has a relatively large volume and a relatively stable center of gravity, and the base 5 has a relatively small weight to increase the portability of the base 5.

[0109] It is understood that the base 5 can be of any shape with a stable center of gravity. As some examples, Fig.14 As shown, the main body shape of the base 5 is a prism shape.

[0110] Combination Figure 7 , Fig.10 and Fig.14 As shown, optionally, the mounting portion 522 is provided with a plurality of locking structures 5222, and the plurality of locking structures 5222 are located in the mounting cavity 5221 and are spaced apart in the circumferential direction of the mounting portion 522, and the end of the sample dilution tube 4 protrudes from the inside to the outside to form a locking flange 43, and in the extension direction of the locking structure 5222, the locking flange 43 abuts against the locking structure 5222.

[0111] Combination Figure 8 , Fig. 9 , Fig.10 and Fig.14 As shown, the first bottom shell 51 and the base portion 521 are connected by a snap-fit ​​structure, so that the first bottom shell 51 and the base portion 521 can be easily installed during production, and the first bottom shell 51 and the base portion 521 can be more stably connected.

[0112] Combination Figure 6 , Figure 7 , Fig.14 As shown, in some embodiments, the inner wall of the sample dilution tube 4 is provided with a protrusion 42, and at least one of the sampling head 2 and the housing 1 is interference-connected with the protrusion 42 to make the accommodating chamber 41 in an airtight state.

[0113] like Figure 6 As shown, specifically, the housing 1 and the protruding portion 42 are in interference connection, so that the accommodating cavity 41 is in an airtight state.

[0114] In some embodiments, the containing chamber 41 contains a sample diluent, and the sample diluent tube 4 is provided with a sealing sheet for closing the first opening 4111, and the sealing sheet is configured to be destroyed by squeezing.

[0115] When the sample diluent is needed, the sealing sheet is squeezed by the sampling head 2 to break the sealing sheet, so that the sampling head 2 can extend into the accommodating cavity 41 and be in a connected state.

[0116] The sealing sheet can seal and protect the sample diluent, thereby preventing the sample diluent from leaking and reducing the risk of contamination of the sample diluent.

[0117] Preferably, the sealing sheet is an aluminum foil sheet, which has a good sealing and protection effect on the sample diluent, and the aluminum foil sheet can be destroyed when squeezed.

[0118] Combination Figure 3 , Fig.12 and Fig.13 As shown, in some embodiments, the shell 1 defines a detection cavity 11, the sampling head 2 is inserted into the shell 1 and is located in the detection cavity 11, the detection component 3 includes a bracket 31 and a test strip 32 that cooperates with the sampling head 2, the bracket 31 includes a frame 311, a first connecting portion 312 and a second connecting portion 313, the frame 311 is detachably arranged in the detection cavity 11 and defines a mounting groove 3111, the first connecting portion 312 is connected to the frame 311 and is located in the mounting groove 3111, the test strip 32 is arranged in the mounting groove 3111 and is connected to the first connecting portion 312, and the second connecting portion 313 is located on the outer peripheral wall of the frame 311 and is connected to the frame 311.

[0119] It is understandable that there may be one or more test strips 32 in the detection cavity 11 .

[0120] The test strip 32 is disposed in the mounting groove 3111, and the first connection portion 312 is connected to the test strip 32, so that the test strip 32 can be more firmly disposed in the mounting groove 3111. The second connection portion 313 is located on the outer peripheral wall of the frame 311 and is connected to the frame 311, so that the bracket 31 can be fixed. The bracket 31 can support the test strip 32 to reduce the risk of bending and dislocation of the test strip 32 in the detection cavity.

[0121] The frame 311 is detachably provided in the detection chamber 11 and defines a mounting groove 3111. The test strip 32 can be easily taken out through the frame 311 to facilitate replacement of the test strip 32 or reading of the test result. The frame 311 can facilitate installation of the test strip 32 into the detection chamber 11. Since the frame 311 supports the test strip 32, the frame 311 can reduce the risk of bending and dislocation of the test strip 32 in the detection chamber.

[0122] Specifically, at least a portion of the filter portion 22 is inserted into the housing 1 and is located in the detection cavity 11 , and the test strip 32 cooperates with the filter element 23 .

[0123] The test strip 32 and the filter element 23 may be matched so that the filter element 23 abuts against the test strip 32, so that the test strip 32 can receive the sample in the filter element 23 and perform the test. The test strip 32 and the filter element 23 may also be matched so that when the test strip 32 can receive the sample in the filter element 23, a certain distance is spaced between the test strip 32 and the filter element 23, so that the test strip 32 can receive the sample in the filter element 23 for the test.

[0124] By inserting at least part of the filter portion 22 into the housing 1 and locating it in the detection chamber 11, the sampling head 2 can be installed on the housing 1, and the test strip 32 cooperates with the filter element 23 so that the test strip 32 can receive the sample filtered by the filter element 23, thereby making the structural distribution of the sample collection and detection device 100 more reasonable.

[0125] Combination Figure 6 and Fig.12 As shown, optionally, a fourth opening 3112 is formed at one end of the frame 311 close to the filter element 23 , and one end of the test strip 32 close to the filter element 23 extends out of the fourth opening 3112 and cooperates with the filter element 23 .

[0126] The fourth opening 3112 is provided to facilitate the cooperation between the test strip 32 and the filter element 23 , thereby making the structure of the frame 311 reasonable.

[0127] Combination Fig.12 and Fig.13 As shown, optionally, a plurality of first connection portions 312 are provided, and in the width direction of the test strip 32, at least one first connection portion 312 is located on one side of the test strip 32, and at least another first connection portion 312 is located on the other side of the test strip 32, and each first connection portion 312 abuts against the test strip 32.

[0128] By having at least one first connection portion 312 located on one side of the test strip 32 and at least another first connection portion 312 located on the other side of the test strip 32 , the connection stability between the first connection portion 312 and the test strip 32 is increased so that the test strip 32 can be more firmly disposed in the mounting groove 3111 .

[0129] As some examples, the width direction of the test strip 32 is as follows: Fig.13 As indicated by the arrow at d in the middle.

[0130] Combination Fig.12 and Fig.13 As shown, as some examples, four first connection parts 312 are provided. In the width direction of the test strip 32, the four first connection parts 312 are arranged opposite to each other in pairs, thereby increasing the connection stability between the first connection parts 312 and the test strip 32, so that the test strip 32 can be more firmly set in the installation groove 3111.

[0131] like Fig.12As shown, optionally, a plurality of second connection parts 313 are provided, at least one second connection part 313 is located on one side of the frame 311 , at least another second connection part 313 is located on the other side of the frame 311 , and each second connection part 313 abuts against the shell 1 .

[0132] By having at least one second connection portion 313 located on one side of the frame 311 and at least another second connection portion 313 located on the other side of the frame 311 , the connection stability between the second connection portion 313 and the shell 1 is increased, so that the frame 311 can be more firmly arranged in the installation groove 3111 .

[0133] like Fig.12 As shown, in some embodiments, the frame 311 defines a mounting slot 3111, and the test strip 32 is disposed in the mounting slot 3111 and connected to the first connecting portion 312. By providing a mounting slot 3111, at least one item can be tested.

[0134] like Fig.15 As shown, in other embodiments, the frame 311 defines a plurality of mounting grooves 3111 in the circumferential direction of the frame 311. A first connecting portion 312 is disposed in each mounting groove 3111, and a plurality of test strips 32 are disposed in the plurality of mounting grooves 3111 and connected to the first connecting portion 312 in a one-to-one correspondence.

[0135] As some examples, the number of the plurality of mounting slots 3111 may be 2, 3, or 4.

[0136] By providing a plurality of mounting slots 3111 , a plurality of test strips 32 can be accommodated, and a plurality of items can be tested through the plurality of test strips 32 , thereby realizing multi-link testing.

[0137] Optionally, each test strip 32 has one or more T lines (Test lines). This allows the test strip 32 to test different items. For example, the test strip 32 has three T lines and one C line (Control line). The three T lines reflect the test results, and the C line is used to control the process and determine the validity of the results.

[0138] Preferably, the number of T lines on each test strip 32 is less than or equal to three.

[0139] Combination Fig.15 and Fig.16 As shown, in some embodiments, the housing 1 is provided with a plurality of transparent windows 12 , and the plurality of windows 12 are arranged in a one-to-one correspondence with the plurality of test strips 32 .

[0140] The test result of the test strip 32 can be read through the window portion 12, thereby increasing the convenience of reading the test result.

[0141] like Figure 1 , Figure 2 , Figure 3 and Fig.13 As shown, in some embodiments, the test strip 32 includes a laminated absorbent paper 322 for absorbing water, a nitrocellulose membrane 321, a coupling pad 323 including a labeled protein, and a sample pad 324 for absorbing and pretreating the sample, and the shell 1 is provided with a transparent window portion 12, which is located on the side of the test strip 32 close to the nitrocellulose membrane 321.

[0142] The labeled protein carried by the coupling pad 323 reacts with the corresponding detection substance in the sample, and the reaction product acts on the nitrocellulose membrane 321, causing the nitrocellulose membrane 321 to develop color or emit light, thereby realizing the detection of the sample.

[0143] The absorbent paper 322 can increase the chromatography effect of the test strip 32, so as to increase the accuracy of the detection.

[0144] The test result of the test strip 32 is displayed on the nitrocellulose membrane 321 , and the transparent window portion 12 is located on the side of the test strip 32 close to the nitrocellulose membrane 321 . The test result can be read through the transparent window portion 12 , thereby increasing the convenience of reading the test result.

[0145] like Fig.13 As shown, specifically, the nitrocellulose membrane 321 has a quality control line 3211 and a detection line 3212. The quality control line 3211 and the detection line 3212 can more accurately judge the detection result.

[0146] Combination Figure 3 and Fig.11 As shown, in some embodiments, the sample collection and detection device 100 also includes a tube plug 6 connected to the frame 311, the tube plug 6 can be detachably connected to the shell 1, and is arranged at one end of the detection cavity 11 away from the sampling head 2, the tube plug 6 is provided with a ventilation structure 63, a part of the ventilation structure 63 is connected to the detection cavity 11, and another part of the ventilation structure 63 is connected to the outside, and the sampling head 2 closes one end of the detection cavity 11.

[0147] By making the sampling head 2 seal one end of the detection cavity 11 and arranging the tube plug 6 at the end of the detection cavity 11 away from the sampling head 2, the probability of contact between external gas and the sample can be reduced, and the probability of sample contamination can be further reduced.

[0148] When the sample and the sample diluent enter the capillary channel 211 and the filter section 22, part of the gas in the detection chamber 11 is discharged to the outside of the detection chamber 11 through the ventilation structure 63 to balance the internal and external air pressures of the detection chamber 11, thereby avoiding an increase in the air pressure in the detection chamber 11, and further avoiding the process of the sample and the sample diluent entering the capillary channel 211 and the filter section 22 being inhibited, so that the sample and the sample diluent can smoothly enter the capillary channel 211 and the filter section 22.

[0149] Combination Figure 3 and Fig.11 As shown, optionally, the pipe plug 6 includes a first plug body 61 and a second plug body 62 connected to each other, and the first plug body 61 is plugged into the housing 1 in a detachable manner to close one end of the housing 1. The second plug body 62 is located outside the housing 1 and abuts against the end wall of the housing 1, and the second plug body 62 can facilitate the installation and separation of the first plug body 61.

[0150] Combination Figure 3 and Fig.11 As shown, further, the ventilation structure 63 includes a ventilation channel 631 and an air hole 632. The ventilation channel 631 is provided on the first plug body 61, and the ventilation channel 631 is located in the detection cavity 11 and communicated with the detection cavity 11. The air hole 632 is provided on the second plug body 62, and the air hole 632 is located outside the detection cavity 11. A part of the air hole 632 is communicated with the ventilation channel 631, and another part of the air hole 632 is communicated with the outside.

[0151] When the detection cavity 11 needs to exhaust gas, the gas enters the ventilation channel 631 , enters the air hole 632 through the ventilation channel 631 , and is exhausted to the outside through the air hole 632 .

[0152] By providing the ventilation channel 631 and the air hole 632 , the ventilation structure 63 is adapted to the structure of the tube plug 6 , so that the structural distribution of the ventilation structure 63 and the tube plug 6 is more reasonable, so that the ventilation structure 63 can efficiently discharge the gas in the detection cavity 11 .

[0153] Furthermore, one end of the frame 311 facing away from the filter element 23 is plugged into the first plug 61 , thereby reducing the difficulty of installing and separating the test strip 32 through the tube plug 6 .

[0154] It should be understood that the terms used in the text are only for the purpose of describing specific example embodiments and are not intended to be limiting. Unless the context clearly indicates otherwise, the singular forms "one", "an" and "said" as used in the text may also be meant to include plural forms. The terms "include", "comprise", "contain", and "have" are inclusive, and therefore specify the existence of stated features, steps, operations, elements and / or parts, but do not exclude the existence or addition of one or more other features, steps, operations, elements, parts, and / or combinations thereof. The method steps, processes, and operations described in the text are not interpreted as necessarily requiring them to be performed in the specific order described or illustrated, unless the execution order is clearly indicated. It should also be understood that additional or alternative steps may be used.

[0155] Although the terms first, second, third, etc. can be used in the text to describe multiple elements, components, regions, layers and / or sections, these elements, components, regions, layers and / or sections should not be limited by these terms. These terms can only be used to distinguish an element, component, region, layer or section from another region, layer or section. Unless the context clearly indicates, terms such as "first", "second" and other numerical terms do not imply order or sequence when used in the text. Therefore, the first element, component, region, layer or section discussed below can be referred to as the second element, component, region, layer or section without departing from the teaching of the example embodiments. In the description of the present application, the meaning of "multiple" is at least two, such as two, three, etc., unless otherwise clearly and specifically limited.

[0156] For ease of description, spatial relative terms may be used in the text to describe the relationship of one element or feature relative to another element or feature as shown in the figure, such as "inside", "outside", "inner side", "outer side", "below", "below", "above", "above", etc. Such spatial relative terms are intended to include different orientations of the device in use or operation in addition to the orientation depicted in the figure. For example, if the device in the figure rotates, the element described as "below other elements or features" or "below other elements or features" will then be oriented as "above other elements or features" or "above other elements or features". Therefore, the example term "below..." can include both upper and lower orientations. The device can be oriented otherwise (rotated 90 degrees or in other directions) and the spatial relative descriptors used in the text are interpreted accordingly.

[0157] In the description of the application, the orientation or position relationship indicated by technical terms such as "length", "width", "thickness", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", "circumferential", "height direction", "first direction", "second direction", etc. is based on the orientation or position relationship shown in the accompanying drawings, which is only for the convenience of describing the embodiments of the present application and simplifying the description, and does not indicate or imply that the referred device or element must have a specific orientation, be constructed, operated or used in a specific orientation, and therefore cannot be understood as a limitation on the embodiments of the present application.

[0158] In this application, unless otherwise clearly specified and limited, the terms "installed", "connected", "connected", "fixed" and the like should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection, an electrical connection, or communication with each other; it can be a direct connection, or an indirect connection through an intermediate medium, it can be the internal connection of two elements or the interaction relationship between two elements, unless otherwise clearly defined. For ordinary technicians in this field, the specific meanings of the above terms in this application can be understood according to specific circumstances.

[0159] The above is only a preferred specific implementation of the present application, but the protection scope of the present application is not limited thereto. Any changes or substitutions that can be easily thought of by a person skilled in the art within the technical scope disclosed in the present application should be included in the protection scope of the present application. Therefore, the protection scope of the present application should be based on the protection scope of the claims.

Claims

1. A sample collection and detection device, characterized in that: include: case; A sampling head is installed on the housing, the sampling head is provided with a capillary channel, the capillary channel has a preset volume, and is used for quantitatively collecting samples; A detection component is disposed in the shell, and the detection component cooperates with the sampling head to receive the sample and detect the sample.

2. The sample collection and detection device according to claim 1, characterized in that: The sampling head comprises: A sampling portion, provided with the capillary channel, wherein the capillary channel runs through the sampling portion; A filter part connected to the sampling part, the filter part is installed on the housing and defines a filter cavity communicating with the capillary channel; The filter element is arranged in the filter cavity and cooperates with the detection component.

3. The sample collection and detection device according to claim 2, characterized in that: The sampling portion has a contact end surface suitable for contact sampling, the contact end surface is located on the side of the sampling portion away from the filtering portion, the contact end surface includes a contact surface and a transition surface connected to each other, at least part of the transition surface is located on the side of the contact surface close to the filtering portion, and one end of the capillary channel passes through the contact surface.

4. The sample collection and detection device according to claim 3, characterized in that: The contact end surface is an arc-shaped surface; and / or, The volume of the capillary channel is 1 μl-500 μl.

5. The sample collection and detection device according to any one of claims 1 to 4, characterized in that: The sample collection and detection device further comprises a sample dilution tube, wherein the sample dilution tube defines a receiving cavity with a first opening formed at one end, wherein the receiving cavity is suitable for receiving the sample dilution liquid, and the sampling head has a separation state and a connection state relative to the receiving cavity, wherein the sampling head in the separation state is separated from the receiving cavity, When the sampling head is in the connected state, the sampling head is movably disposed in the accommodating cavity through the first opening, and at least one of the sampling head and the shell is interference-connected with the inner wall of the sample diluent tube, so that the accommodating cavity is in an airtight state, so that when the sampling head is configured to move in a direction close to the bottom wall of the accommodating cavity, the sample diluent can be squeezed into the capillary channel.

6. The sample collection and detection device according to claim 5, characterized in that: The accommodating cavity comprises a first accommodating cavity and a second accommodating cavity, the first accommodating cavity has the first opening, the second accommodating cavity is located at a side of the first accommodating cavity away from the first opening, the second accommodating cavity is formed with a second opening, and the volume of the second accommodating cavity is smaller than the volume of the first accommodating cavity; When the sampling head is in the connected state, in the length direction of the shell, the sampling head is movably arranged in the accommodating cavity between a first position and a second position. When the sampling head is in the first position, the second accommodating cavity is communicated with the first accommodating cavity through the second opening. The sampling head in the second position closes the second opening to make the second accommodating cavity in an airtight state, so that the sampling head is configured to squeeze the sample diluent into the capillary channel.

7. The sample collection and detection device according to claim 6, characterized in that: The sample collection and detection device further comprises a base, wherein the base comprises a first bottom shell and a second bottom shell, wherein the second bottom shell comprises a base portion and a mounting portion, wherein the base portion is connected to the first bottom shell and defines a cavity. One end of the mounting portion is connected to the base portion, and the other end of the mounting portion is in contact with the first bottom shell. The mounting portion is located in the mold cavity and defines the mounting cavity. The sample dilution tube is installed in the mounting cavity. The first bottom shell is provided with a third opening communicating with the accommodating cavity; and / or, The containing cavity contains the sample diluent, the sample diluent tube is provided with a sealing sheet for sealing the first opening, and the sealing sheet is configured to be destroyed by extrusion; and / or, The inner wall of the sample dilution tube is provided with a convex portion, and at least one of the sampling head and the shell is interference-connected with the convex portion.

8. The sample collection and detection device according to any one of claims 1 to 4, characterized in that: The shell defines a detection cavity, the sampling head is inserted into the shell and is located in the detection cavity, the detection component includes a bracket and a test strip that cooperates with the sampling head, the bracket includes a frame, a first connecting part and a second connecting part, the frame can be detachably arranged in the detection cavity and defines a mounting groove, the first connecting part is connected to the frame and is located in the mounting groove, the test strip is arranged in the mounting groove and connected to the first connecting part, and the second connecting part is located on the outer peripheral wall of the frame and connected to the frame.

9. The sample collection and detection device according to claim 8, characterized in that: In the circumferential direction of the frame, the frame defines a plurality of the installation grooves, each of the installation grooves is provided with the first connecting portion, a plurality of the test strips are provided, and the plurality of test strips are arranged in the plurality of the installation grooves in a one-to-one correspondence and connected to the first connecting portion.

10. The sample collection and detection device according to claim 9, characterized in that: The housing is provided with a plurality of transparent windows, and the plurality of windows are arranged in a one-to-one correspondence with the plurality of test strips.

11. The sample collection and detection device according to claim 8, characterized in that: The test strip comprises laminated absorbent paper for absorbing water, a nitrocellulose membrane, a coupling pad comprising a labeled protein and a sample pad for absorbing and pretreating the sample, and the shell is provided with a transparent window portion, which is located on a side of the test strip close to the nitrocellulose membrane.

12. The sample collection and detection device according to claim 8, characterized in that: The sample collection and detection device also includes a tube plug connected to the frame, the tube plug can be detachably connected to the shell, and is arranged at one end of the detection cavity away from the sampling head. The tube plug is provided with a ventilation structure, a part of the ventilation structure is connected to the detection cavity, and another part of the ventilation structure is connected to the outside world. The sampling head closes one end of the detection cavity.

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