Sample processing apparatus
By designing sample processing equipment, using technical means such as transmission tracks and spacing devices, the automated processing of samples is realized, the problem of time-consuming and labor-consuming manual processing is solved, and the efficiency of sample processing and the timeliness of detection are improved.
Patent Information
- Application Number
- CN202420005954.0
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-01-02
- Publication Date
- 2025-03-18
- Estimated Expiration
- 2034-01-02
AI Technical Summary
In the medical field, in the face of a large number of samples to be tested, manual sample registration, inspection and placement is time-consuming and labor-intensive, and it is difficult to meet the requirements of efficient testing.
A sample processing device is designed, including a sample transport device and a sample finishing device. The sample transport device transmits the sample through a transmission track extending in the axial direction, and the sample finishing device uses a spacing divider, a first drive mechanism and a second drive mechanism to realize automatic clamping, moving and arranging of the samples.
The equipment can automate the collection, transmission and sorting of samples, improve the efficiency of sample processing, save labor costs, and meet the timeliness requirements of efficient testing.
Smart Images

Figure CN222636172U_ABST
Abstract
Description
Technical Field
[0001] At least one embodiment of the present disclosure relates to a sample processing device. Background Art
[0002] In the medical field, the substances to be tested are usually placed in containers such as tubular containers. The tubular containers containing the substances to be tested are called samples. It is necessary to register the information of each sample, check whether the sample meets the requirements, and organize and arrange multiple samples in order to prepare for the test. Faced with a large number of samples to be tested, it is time-consuming and labor-intensive to manually register the information of the samples one by one, check whether the samples are qualified, and arrange the samples. Therefore, how to effectively and automatically perform operations such as sampling, transporting samples, and collecting sample information is very important for saving labor costs and meeting the requirements of efficient testing timeliness. Utility Model Content
[0003] At least one embodiment of the present disclosure provides a sample processing device, the sample processing device comprising: a sample transport device and a sample sorting device; the sample transport device comprises a transmission track extending along an axial direction, the transmission track is configured to transport a plurality of samples along the axial direction and the plurality of samples are arranged along the axial direction on the transmission track; the sample sorting device comprises a spacer, a first driving mechanism and a second driving mechanism. The spacer is located on one side of the transmission track in a lateral direction, the lateral direction is perpendicular to the axial direction, and the spacer comprises a plurality of clamping members arranged in the axial direction, each of the plurality of clamping members is configured to clamp a sample located on the transmission track so that the plurality of clamping members clamp a plurality of samples, and the adjacent samples clamped by the plurality of clamping members are arranged at a preset spacing; the first driving mechanism is configured to drive the spacer to move along the axial direction; the second driving mechanism is configured to drive the spacer to move closer to and away from the transmission track in the lateral direction.
[0004] For example, in the sample processing device provided in at least one embodiment of the present disclosure, the divider is configured to clamp the multiple samples when it is located in the initial position, and is configured to move in the lateral direction along the direction close to the transfer track so that the multiple clamping members simultaneously move along the direction close to the transfer track to simultaneously clamp the multiple samples respectively; the divider clamping the multiple samples is configured to be movable in the axial direction to simultaneously move the multiple samples arranged at the preset interval along the transfer track, the divider is configured to move away from the transfer track in the lateral direction to release the multiple samples, and the divider is configured to move along the axial direction to return to the initial position after releasing the multiple samples.
[0005] For example, in the sample processing device provided in at least one embodiment of the present disclosure, the plurality of clamping members are arranged spaced apart from each other in the axial direction.
[0006] For example, in the sample processing device provided in at least one embodiment of the present disclosure, the plurality of clamping members are arranged at equal intervals in the axial direction.
[0007] For example, in the sample processing device provided in at least one embodiment of the present disclosure, the intervals between adjacent clamping members among the plurality of clamping members are adjustable.
[0008] For example, in the sample processing device provided by at least one embodiment of the present disclosure, each of the clamping members includes a strip-shaped main body extending in the longitudinal direction and a clamping portion located at the lower end of the strip-shaped main body and connected to the main body, and the longitudinal direction is perpendicular to both the axial direction and the transverse direction; during the process of the sample being transported by the transfer track, the sample includes an upper portion located above the transfer track and a lower portion located below the transfer track, the upper portion of the transfer track and the lower portion of the transfer track are opposite to each other in the longitudinal direction, and the length of the lower portion in the longitudinal direction is greater than the length of the upper portion in the longitudinal direction; the clamping portion is located below the transfer track in the longitudinal direction to clamp the lower portion of the sample.
[0009] For example, in the sample processing device provided by at least one embodiment of the present disclosure, the transmission track has a first carrier plate and a second carrier plate both extending along the axial direction, and a gap sandwiched between the first carrier plate and the second carrier plate and extending along the axial direction, the first carrier plate has a first track bearing surface facing upward, and the second carrier plate has a second track bearing surface facing upward; in the process of the sample being transported by the transmission track, the sample includes a main body and an end connected to the main body, the main body and the end are arranged in the longitudinal direction, and the orthographic projection of the main body on a plane perpendicular to the longitudinal direction is located within the orthographic projection of the end on a plane perpendicular to the longitudinal direction; the main body has a radial dimension perpendicular to the longitudinal direction, and the end has a radial dimension perpendicular to the longitudinal direction; the width of the gap is smaller than the radial dimension of one end of the sample and larger than the radial dimension of one main body of the sample, the main body of the sample is sandwiched in the gap, and the end of the sample is carried on the first track bearing surface and the second track bearing surface; the end of the sample is the upper part, and the main body of the sample is the lower part.
[0010] For example, in the sample processing device provided in at least one embodiment of the present disclosure, the clamping portion is U-shaped, the U-shaped opening faces the transfer track, the U-shaped clamping portion has side walls located on both sides of the opening, and the side walls located on both sides of the opening are respectively a first side wall and a second side wall; there is a gap between adjacent side walls of two adjacent clamping portions, and the gap between two adjacent clamping members in the axial direction refers to the gap between adjacent side walls of two adjacent clamping portions.
[0011] For example, in the sample processing device provided by at least one embodiment of the present disclosure, the surface of the first side wall facing the second side wall and the surface of the second side wall facing the first side wall are both curved surfaces.
[0012] For example, in the sample processing device provided by at least one embodiment of the present disclosure, the second driving mechanism is located on a side of the divider away from the transmission track in the lateral direction and is connected to the divider.
[0013] For example, in the sample processing device provided in at least one embodiment of the present disclosure, the sample processing device includes a plurality of the dividers, and the plurality of the dividers include a first divider and a second divider arranged at intervals in the axial direction; the first divider and the second divider both have the plurality of clamping members; the sample processing device also includes an information collection area and a sample information collection device, a part of the transmission track is located in the information collection area, the sample information collection device is located in the information collection area, and is configured to collect information of the sample transmitted to the information collection area; in the axial direction, the second divider is located on a side of the first divider close to the information collection area; the first divider is configured to move along the axial direction to the information collection position corresponding to the sample information collection device in the information collection area to clamp it according to the The multiple samples arranged at the preset intervals are moved along the transmission track to the sample information collection device, and the multiple samples are arranged at the preset intervals in the sample information collection device; the second driving mechanism is configured to drive the first spacer to move away from the transmission track in the lateral direction after the first spacer transfers the multiple samples to the sample information collection device, and then the first driving mechanism is configured to drive the first spacer to move away from the second spacer along the axial direction; the second spacer is configured to move along the axial direction to the information collection position to clamp the multiple samples arranged at the preset intervals in the sample information collection device after the information collection is completed and the first spacer leaves the information collection position, and is configured to be movable along the axial direction to move the multiple samples clamped by it.
[0014] For example, in the sample processing equipment provided by at least one embodiment of the present disclosure, the sample information acquisition device includes a sample clamping assembly, the sample clamping assembly includes a plurality of groups of clamping mechanisms arranged in the axial direction, adjacent groups of the clamping mechanisms are spaced apart by the preset spacing in the axial direction, each group of the clamping mechanisms has a accommodating space, the first divider releases each of the samples to the accommodating space accordingly, and each group of the clamping mechanisms is configured to clamp a sample from the first divider; the transmission track has a first supporting plate and a second supporting plate both extending along the axial direction, and a gap sandwiched between the first supporting plate and the second supporting plate and extending along the axial direction; in the process of the plurality of samples being moved along the transmission track under the clamping of the first divider, the plurality of samples are sandwiched in the gap; the orthographic projections of the plurality of clamping mechanisms in the plane defined by the axial direction and the lateral direction at least partially overlap with the orthographic projections of the gaps of the transport track in the plane.
[0015] For example, in the sample processing device provided in at least one embodiment of the present disclosure, the sample includes a nucleic acid detection sampling tube; the main part of the sample is a tube body containing a substance to be detected, and the end of the sample is a tube cover for sealing the tube body, the axial length of the tube body of the sample is greater than the axial length of the tube cover, and the shape of the main part of the sample is cylindrical.
[0016] The sample processing device provided by the embodiment of the present disclosure can be used to process, for example, a tubular sample containing a substance to be detected, for example, a tubular sample is a nucleic acid detection sample. In the sample processing device, by arranging a sample sorting device including a spacer, a first drive mechanism, and a second drive mechanism on one side of the transmission track in the lateral direction, the sample sorting device can cooperate with the functional device in the next processing link to efficiently complete the transmission of multiple samples from the transport track to the functional device in the next processing link at the required preset spacing, and the first spacer can reciprocate in the axial direction to periodically and continuously complete the above-mentioned working process, and meet the need for multiple samples to be arranged at a preset spacing when the next processing link processes the samples simultaneously. BRIEF DESCRIPTION OF THE DRAWINGS
[0017] In order to more clearly illustrate the technical solutions of the embodiments of the present utility model, the drawings of the embodiments will be briefly introduced below. Obviously, the drawings in the following description only relate to some embodiments of the present utility model, rather than limiting the present utility model.
[0018] Figure 1 is a schematic block diagram of a moving path of a sample in a sample processing device provided in an embodiment of the present disclosure;
[0019] Figure 2is a schematic diagram of the overall structure of a sample processing device provided by an embodiment of the present disclosure;
[0020] Figure 3A yes Figure 2 The sample processing device shown is an enlarged schematic diagram of a portion including a sample arrangement device;
[0021] Figure 3B is with Figure 3A A schematic diagram of the structure related to the first divider and the second divider in FIG.
[0022] Figure 4 It is a structural schematic diagram of a spacer of a sample arrangement device of a sample processing device provided in one embodiment of the present disclosure;
[0023] Figure 5 It is a partial schematic diagram of a track of a sample on a transmission track in a sample processing device provided by an embodiment of the present disclosure;
[0024] Figure 6 A schematic block diagram showing the relationship between a control system and various structures of a sample processing device provided in one embodiment of the present disclosure. DETAILED DESCRIPTION
[0025] In order to make the purpose, technical solution and advantages of the embodiment of the utility model clearer, the technical solution of the embodiment of the utility model will be clearly and completely described below in conjunction with the drawings of the embodiment of the utility model. Obviously, the described embodiment is a part of the embodiment of the utility model, not all of the embodiments. Based on the described embodiment of the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.
[0026] Unless otherwise defined, the technical or scientific terms used herein shall have the usual meanings understood by persons with ordinary skills in the field to which the utility model belongs. The words "first", "second" and similar words used in the patent application specification and claims of the utility model do not indicate any order, quantity or importance, but are only used to distinguish different components. Words such as "include" or "comprise" mean that the elements or objects appearing before the word include the elements or objects listed after the word and their equivalents, without excluding other elements or objects. "Inside", "outside" and the like are only used to indicate relative positional relationships. When the absolute position of the described object changes, the relative positional relationship may also change accordingly.
[0027] The dimensions of the drawings used in this disclosure are not drawn strictly according to the actual scale, and the specific dimensions and quantities of each structure can be determined according to actual needs. The drawings described in this disclosure are only schematic diagrams of the structures.
[0028] It should be noted that the “height in the vertical direction” in the present disclosure refers to the height relative to the ground in the vertical direction.
[0029] The inventor of the utility model discovered that in order to improve the sample sorting speed more quickly and efficiently and ensure that the samples meet the requirements, before automatically executing the steps of registering the sample information one by one and checking whether the samples are qualified, it is first necessary to automatically collect the samples one by one and transmit them to the information collection area, and then collect information on the samples in the information collection area. The collected results can be used to determine whether the samples are qualified, and the basic information of each sample can be counted in order.
[0030] At least one embodiment of the present disclosure provides a sample processing device, the sample processing device comprising: a sample transport device and a sample sorting device; the sample transport device comprises a transmission track extending along an axial direction, the transmission track is configured to transport a plurality of samples along the axial direction and the plurality of samples are arranged along the axial direction on the transmission track; the sample sorting device comprises a spacer, a first driving mechanism and a second driving mechanism. The spacer is located on one side of the transmission track in a lateral direction, the lateral direction is perpendicular to the axial direction, and the spacer comprises a plurality of clamping members arranged in the axial direction, each of the plurality of clamping members is configured to clamp a sample located on the transmission track so that the plurality of clamping members clamp a plurality of samples, and the adjacent samples clamped by the plurality of clamping members are arranged at a preset spacing; the first driving mechanism is configured to drive the spacer to move along the axial direction; the second driving mechanism is configured to drive the spacer to move closer to and away from the transmission track in the lateral direction.
[0031] The sample processing device provided by the embodiment of the present disclosure can be used to process, for example, a tubular sample containing a substance to be detected, for example, the tubular sample is a nucleic acid detection sample. In the sample processing device, by arranging a sample sorting device including a spacer, a first drive mechanism and a second drive mechanism on one side of the transmission track in the lateral direction, the sample sorting device can cooperate with the functional device in the next processing link to efficiently complete the transmission of multiple samples from the transportation track to the functional device in the next processing link at the required preset spacing, and the first spacer can reciprocate in the axial direction to periodically and continuously complete the above-mentioned working process, and meet the need for multiple samples to be arranged at a preset spacing when the next processing link processes the samples at the same time, thereby improving the working efficiency and being able to efficiently process a large number of samples.
[0032] For example, Figure 1 is a schematic block diagram of a moving path of a sample in a sample processing device provided by an embodiment of the present disclosure, Figure 2 is a schematic diagram of the overall structure of a sample processing device provided by an embodiment of the present disclosure, Figure 3A yes Figure 2 The sample processing device shown is an enlarged schematic diagram of a part including a sample arrangement device, Figure 3B is with Figure 3A Schematic diagram of the structure of the first divider and the second divider in FIG. Figure 1-Figure 3B , a sample processing device 100 provided in an embodiment of the present disclosure includes: a sample transport device 20 and a sample sorting device 50. The sample transport device 200 includes a transmission track 22 extending along the axial direction D2, and the transmission track 22 is configured to transport a plurality of samples 6 along the axial direction D2 and the plurality of samples 6 are arranged along the axial direction D2 on the transmission track 22. The sample sorting device 50 includes a divider 51, a first driving mechanism 5a and a second driving mechanism 5b. The divider 51 is located on one side of the transmission track 22 in the transverse direction D3, and the transverse direction D3 is perpendicular to the axial direction D2. The divider 51 includes a first divider 501, and the first divider 501 is taken as an example for description. The first divider 501 includes a plurality of clamping members 05 arranged in the axial direction D2, each of the plurality of clamping members 05 is configured to clamp a sample 6 so that the plurality of clamping members 05 clamp a plurality of samples 6, and adjacent samples 6 clamped by the plurality of clamping members 05 are arranged at a preset interval in the axial direction D2; the first driving mechanism 5a is configured to drive the first divider 501 to move along the axial direction D2; the second driving mechanism 5b is configured to drive the first divider 501 to move toward and away from the transmission track 22 in the lateral direction D3. Figure 2 is a top view. Figure 2 In the figure, the longitudinal direction D1 is perpendicular to the picture, for example, is perpendicular to the ground.
[0033] The sample processing device 100 provided in the embodiment of the present disclosure can be used to process, for example, a sample 6 containing a substance to be detected, where the sample 6 is a sampling tube, and the sampling tube contains the substance to be detected taken from the test individual (e.g., human body). For example, the sample 6 is a tubular sample, such as a nucleic acid test sample, and of course it can also be a sample for other tests. For example, the sample processing device 100 can be used to collect, transmit, and organize these samples 6, as well as collect information on the samples 6, etc.
[0034] In the sample processing device, a first divider 501 is provided on one side of the transfer track 22 in the transverse direction D3, and a plurality of clamping members 05 of the first divider 501 are used to hold the first divider 501 in the initial position ( Figure 3APosition 1) clamps multiple samples 6 and arranges the clamped multiple samples 6 at a preset pitch in the axial direction D2; the first divider 501 can be driven by the second driving mechanism 5b to move in the lateral direction D3 close to the transmission track 22 to clamp multiple samples 6, and then, the first divider 501 can be driven by the first driving mechanism 5a to move along the axial direction D2 to move the clamped multiple samples 6 arranged at a preset pitch along the transmission track 22, so that the multiple samples 6 can be transported to the next processing link along the axial direction D2, for example, the clamped multiple samples 6 arranged at a preset pitch are released to the functional device in the next processing link and the multiple samples are kept arranged at a preset pitch in the functional device, so as to meet the need of arranging multiple samples at a preset pitch when the next processing link processes the samples 6 at the same time. In addition, when the first divider 501 reaches the position of the corresponding functional device in the next processing link ( Figure 3A , after reaching position 2), the second driving mechanism 5b can be used to drive the first divider 501 to move away from the transfer track 22 in the lateral direction D3 so that the first divider 501 releases the multiple samples 6 to the functional device in the next processing link, and then, the first driving mechanism 5a can be used to drive the first divider 501 to move along the axial direction D2 and return to the initial position, and continue to clamp the multiple samples 6 on the transfer track 22 at the initial position, repeat this working cycle, so as to achieve the first divider and the functional device in the next processing link to cooperate, and efficiently transfer the multiple samples to the functional device at a preset spacing to meet the preset spacing requirements of the accommodating device for accommodating multiple samples in the functional device. In summary, the sample sorting device can cooperate with the functional device in the next processing link to efficiently complete the transmission of multiple samples from the transport track to the functional device in the next processing link at the required preset spacing, and the first divider can reciprocate in the axial direction to periodically and continuously complete the above-mentioned working process, and meet the need of the next processing link to arrange multiple samples at a preset spacing when processing samples at the same time, thereby improving work efficiency and being able to efficiently process a large number of samples.
[0035] For example, refer to Figure 2The sample processing device 100 further includes a sample collection device 10. The sample collection device 10 includes a movable transmission mechanism 3t, and is configured to collect a sample 6 and transfer the sample to the movable transmission mechanism 3t along the longitudinal direction D1; the sample transport device 200 is configured to receive the sample 6 from the movable transmission mechanism 3t, and the sample 6 is moved to the transmission track 22. For example, the sample transport device 200 includes an inclined track 21 and a horizontal track, and the horizontal track is the above-mentioned transmission track 22. The extending direction of the inclined track 21 intersects the longitudinal direction D1, and the inclined track 21 has a first end 21a and a second end 21b in the extending direction thereof, and the height of the second end 21b of the inclined track 21 in the longitudinal direction D1 is lower than the height of the first end 21a of the inclined track 21 in the longitudinal direction D1; the inclined track 21 includes a first slit 210, and the extending direction of the first slit 210 is consistent with the extending direction of the inclined track 21, and the inclined track 21 is configured to receive a sample from the movable transmission mechanism 3t, and the sample 6 is clamped in the first slit 210 and is inclined along the extending direction of the first slit 210. The first end 21a of the track 21 moves to the second end 21b of the inclined track 21; the transmission track 22 is connected to the second end 21b of the inclined track 21, and extends along a horizontal direction intersecting the extension direction of the inclined track 21 (for example, the axial direction D1 is a horizontal direction, for example, the horizontal direction is basically parallel to the direction of the ground, and is not limited to being absolutely parallel), and has a second gap 220 (that is, the gap of the transmission track) extending along the horizontal direction. After passing through the inclined track, multiple samples 6 enter the second gap 220 in turn under the action of gravity, and are clamped in the second gap 220 to move along the axial direction D2 in the inclined track.
[0036] For example, refer to Figure 3A , the first divider 501 is configured to clamp the multiple samples when it is located at the initial position (position 1), and the first divider 501 moves in the direction close to the transmission track 22 in the transverse direction D3 so that the multiple clamping members 05 move simultaneously in the direction close to the transmission track 22 to clamp the multiple samples 6 respectively at the same time; the first divider 501 clamping the multiple samples 6 is configured to be movable in the axial direction D2 to move the multiple samples arranged at a preset interval along the transmission track 22, for example, to position 2; and, at position 2, the first divider 501 is configured to be movable away from the transmission track 22 in the transverse direction D3 to release the multiple samples 6, for example, release the multiple samples 6 to the functional device in the next processing link (for example, a sample information acquisition device 40 for collecting sample information), and then, the first driving mechanism 5a is used to drive the first divider 501 to move along the axial direction D2 to continue to perform the step of clamping the multiple samples 6 on the transportation track, for example, the first divider 501 returns to the initial position to clamp the multiple samples 6 on the transportation track, and continues to perform the above-mentioned working process periodically.
[0037] The multiple clamping members 05 can simultaneously move the multiple samples 6 clamped by the multiple clamping members 05 in the lateral direction D3 away from the transfer track 22, and can simultaneously move the multiple samples 6 clamped by the multiple clamping members 05 along the axial direction D2 to remove the multiple samples 6 from the transfer track 22 and maintain the axial direction D2 during the movement.
[0038] Figure 4 is a schematic diagram of the structure of a spacer of a sample arrangement device of a sample processing device provided by an embodiment of the present disclosure. Figure 4 In a spacer, for example, in the first spacer 501, a plurality of clamping members 05 are arranged in an axial direction D2 and spaced apart from each other. There is a preset interval SP between two adjacent clamping members 05, so that the adjacent samples clamped by the plurality of clamping members 05 maintain a preset spacing.
[0039] For example, multiple clamping members 05 are arranged at equal intervals in the axial direction D2 to meet the requirement of making the spacing between adjacent samples clamped by the multiple clamping members 05 equal, which is convenient for the balance and convenience of operation, and the uniformity of the operation of multiple samples arranged at equal intervals by the functional components cooperating with the first divider 501 in the next process.
[0040] For example, the spacing SP between adjacent clamping members 05 in the multiple clamping members 05 is adjustable to adjust the preset spacing between adjacent samples 6 in the multiple samples 6 clamped by the multiple clamping members 05, meet the requirements for different preset spacings, increase the flexibility of the sample sorting device, and expand the applicable scenarios.
[0041] For example, refer to Figure 4 Each clamping member 05 includes a strip-shaped body 051 extending along a longitudinal direction D1 and a clamping portion 052 located at the lower end of the strip-shaped body 051 and connected to the body. The longitudinal direction D1 is perpendicular to both the axial direction D2 and the transverse direction D3. Figure 3AIn the process of the sample 6 being transported by the transport track 22, the sample 6 includes an upper portion located above the transport track 22 and a lower portion located below the transport track 22, the upper portion of the transport track 22 and the lower portion of the transport track 22 are opposite to each other in the longitudinal direction D1, and the length of the lower portion in the longitudinal direction D1 is greater than the length of the upper portion in the longitudinal direction D1; the clamping portion 052 is located below the transport track 22 in the longitudinal direction D1 to clamp the lower portion of the sample 6. The strip-shaped body 051 can be adapted to the tubular sample 6, and when the clamping member 05 clamps the sample 6, the strip-shaped body 051 can better support and protect the sample 6, which can not only enhance the stability of the end clamping portion 052 thereof, but also facilitate the stability of the clamped sample. In this way, by designing the positional relationship among the clamping member 05, the transmission track 22 and the sample 6, these components cooperate with each other in structure, so as to facilitate the clamping portion 052 at the lower end of the clamping member 05 to move to a position close to the lower part of the sample 6 to stably clamp the longer lower part of the sample 6, thereby improving the operability of the first divider 501 and improving the reliability of the first divider 501 moving in the direction close to the transmission track 22 in the lateral direction D3 to clamp the lower part of the sample 6 clamped in the second gap 220 of the transmission track 22.
[0042] Figure 5 FIG. 1 is a partial schematic diagram of a track of a sample on a transmission track in a sample processing device provided by an embodiment of the present disclosure. Figure 5 The transmission track 22 has a first carrier plate 22a and a second carrier plate 22b, both extending along the axial direction D2, and a second gap 220 sandwiched between the first carrier plate 22a and the second carrier plate 22b and extending along the axial direction D2. The first carrier plate 22a has a first track bearing surface 221 facing upward, and the second carrier plate 22b has a second track bearing surface 222 facing upward. When the sample 6 is transported by the transmission track 22, the sample 6 includes a main body 6a and an end 6b connected to the main body 6a. The main body 6a and the end 6b are arranged in the longitudinal direction D1, and the orthographic projection of the main body 6a on a plane perpendicular to the longitudinal direction D1 is located within the orthographic projection of the end 6b on a plane perpendicular to the longitudinal direction D1. The main part 6a has a radial dimension perpendicular to the longitudinal direction D1, and the end part 6b has a radial dimension perpendicular to the longitudinal direction D1. The width of the gap 220 is smaller than the radial dimension of the end part 6b of a sample 6 and larger than the radial dimension of the main part 6a of a sample 6. The main part 6a of the sample 6 is clamped in the gap 220, and the end part 6b of the sample 6 is supported on the first track bearing surface 221 and the second track bearing surface 222; the end part 6b of the sample 6 is the upper part, and the main part 6a of the sample 6 is the lower part.
[0043] For example, the sample 6 is a sampling tube, such as a blood sampling tube, an epidemic detection sampling tube, etc. Of course, the sample 6 can also be other types of detection tubes. It can be selected according to specific needs. The main body 6a of the sample 6 is the tube body of the sampling tube containing the substance to be detected, and the end 6b of the sample 6 is a tube cover for sealing the sampling tube. The length of the tube body in the axial direction D2 is greater than the length of the tube cover in the axial direction D2. The main body 6a of the sample 6 is cylindrical.
[0044] For example, the clamping portion 052 is U-shaped, and the U-shaped opening faces the transmission track 22. The U-shaped clamping portion 052 has side walls located on both sides of the opening OP, namely, the first side wall SW1 and the second side wall SW2. There is a spacing SP between the adjacent side walls of the two adjacent clamping portions, so that among the multiple samples clamped by the multiple clamping portions 052, the adjacent samples are arranged at a preset spacing. The spacing between two adjacent clamping members 05 in the axial direction D2 refers to the spacing between the adjacent side walls of the two adjacent clamping portions. The clamping portion 052 includes a clamping surface, which includes the arc-shaped bottom surface of the U-shaped opening, the surface of the first side wall SW1 facing the second side wall SW2, and the surface of the second side wall SW2 facing the first side wall SW1. When the clamping portion 052 clamps the sample 6, at least part of the above-mentioned clamping surface abuts against the sample 6, for example, abuts against the main body 6a of the sample 6, so as to apply a clamping force to the sample 6. The U-shaped opening can better adapt to the shape of a columnar sample, such as a cylindrical sample, and can clamp the cylindrical sample more firmly.
[0045] For example, the surface of the first side wall SW1 facing the second side wall SW2, and the surface of the second side wall SW2 facing the first side wall SW1 may be curved surfaces to complement the outer surface shape of the tube body of the cylindrical sample and enhance the clamping stability of the cylindrical sample. The "U-shape" here is not a strict U-shape, that is, the surface of the first side wall SW1 facing the second side wall SW2, and the surface of the second side wall SW2 facing the first side wall SW1 are not necessarily flat surfaces.
[0046] For example, the sample processing device 100 includes a plurality of dividers 51, the plurality of dividers 51 include a first divider 501 and a second divider 502 arranged at intervals in the axial direction D2, the second divider 502 also has a plurality of clamping members 05A, and the structure of the plurality of clamping members 05A may be the same or similar to the structure of the plurality of clamping members 05 of the first divider 501, please refer to the previous description of the plurality of clamping members 05 of the first divider 501. For example, similar to the above description of the specific structure and movement mode of the first divider 501, the sample sorting device 50 also includes a first driving mechanism and a second driving mechanism 5c corresponding to the second divider 502 to respectively drive the second divider 502 to move close to the transfer track 22 in the lateral direction D3, and to move away from the transfer track 22 in the lateral direction D3.
[0047] refer to Figure 2 For example, the sample processing device 100 further includes an information collection area R1 and a sample information collection device 40. A portion of the transmission track 22 is located in the information collection area R1, and the sample 6 is transferred to the information collection area R1 along the transmission track 22; the sample information collection device 40 is located in the information collection area R1, and is configured to collect information of the sample 6 transferred to the information collection area R1. In the axial direction D2, the second divider 502 is located on the side of the first divider 501 close to the information collection area R1. The first divider 501 is configured to be movable along the axial direction D2 to the information collection position ( Figure 3A The second drive mechanism is configured to drive the first divider to move laterally away from the transmission track after the first divider transfers the multiple samples to the sample information collection device, and then the first drive mechanism is configured to drive the first divider to move away from the second divider along the axial direction D2. The second divider 502 is configured to move along the axial direction D2 to the information collection position to clamp the multiple samples arranged at the preset spacing in the sample information collection device after the information collection is completed and the first divider 501 leaves the information collection position, and is configured to be movable along the axial direction D2 to move the multiple samples 6 clamped by it, for example, moving along the axial direction D2 away from the first divider 501 to move the multiple samples 6 clamped by it to the position 3 of the next link, so as to perform further processing on the multiple samples 6.
[0048] For example, refer to Figure 2and 3, the sample information acquisition device 40 includes a sample clamping assembly 400, the sample clamping assembly 400 includes a plurality of groups of clamping mechanisms 41 arranged at intervals in the axial direction D2, adjacent groups of clamping mechanisms 41 are spaced apart in the axial direction by the above-mentioned preset spacing, that is, the distance between adjacent groups of clamping mechanisms 41 in the axial direction D2 is substantially equal to the distance between adjacent samples 6 clamped by the first divider 501 in the axial direction D2; each group of clamping mechanisms 41 has a accommodating space, the first divider 501 releases each sample 6 to the accommodating space accordingly, and each group of clamping mechanisms 41 is configured to clamp a sample from the first divider 501. In the process of multiple samples 6 being moved along the transmission track 22 under the clamping of the first divider 501, the multiple samples 6 are always clamped in the second gap 220, and the orthographic projections of the multiple clamping mechanisms 41 in the plane defined by the axial direction D2 and the lateral direction D3 at least partially overlap with the orthographic projections of the second gap 220 of the transmission track 22 in the plane. Therefore, when the multiple samples 6 are moved to position 2 along the transmission track 22 under the clamping of the first divider 501, as long as the first divider 501 moves away from the transmission track 22 along the lateral direction D3, the multiple samples 6 can be released one by one into the accommodating spaces of the multiple groups of clamping mechanisms 41. This design utilizes the structural coordination between the transmission track 22, the multiple clamping mechanisms 41 and the first divider 501, simplifies the structure of the sample processing equipment, is conducive to ensuring the continuity and smoothness of the operation process, improving the operation efficiency, and efficiently processing a large number of samples 6.
[0049] Here, "the distance between adjacent groups of clamping mechanisms 41 in the axial direction D2 is basically equal to the distance between adjacent samples 6 clamped by the first divider 501 in the axial direction D2", which is not limited to being strictly equal. As long as the first divider 501 can be moved away from the transmission track 22 along the lateral direction D3, multiple samples 6 can be released one by one into the accommodation space of multiple groups of clamping mechanisms 41.
[0050] Figure 6 is a schematic diagram of the relationship between the control system and various structures of a sample processing device provided by an embodiment of the present disclosure. Figure 6 The sample processing device 100 also includes a control system 4, which is signal-connected to the sample information acquisition device 40 (wireless signal connection or wired signal connection such as electrical connection), and is configured to control the sample information acquisition device 40 to collect information on multiple samples located in the information acquisition area R1.
[0051] For example, refer to Figure 6The control system 4 is also signal-connected to the first drive mechanism 2a and the second drive mechanism 2b respectively (wireless signal connection or wired signal connection such as electrical connection), and is configured to control the first drive mechanism 2a and the second drive mechanism 2b to perform work and working parameters respectively, and the working parameters include, for example, motor speed, motor working time, etc.
[0052] The above description is merely an exemplary embodiment of the present invention and is not intended to limit the protection scope of the present invention. The protection scope of the present invention is determined by the appended claims.
Claims
1. A sample processing device, characterized in that: The sample processing device comprises: A sample transport device, comprising a transport track extending in an axial direction, wherein the transport track is configured to transport a plurality of samples in the axial direction and the plurality of samples are arranged in the axial direction on the transport track; and Sample preparation device, comprising: A spacer, wherein the spacer is located on one side of the transmission track in a lateral direction, the lateral direction is perpendicular to the axial direction, and the spacer includes a plurality of clamping members arranged in the axial direction, each of the plurality of clamping members is configured to clamp a sample located on the transmission track so that the plurality of clamping members clamp a plurality of samples, and the adjacent samples clamped by the plurality of clamping members are arranged at a preset interval; A first driving mechanism is configured to drive the divider to move along the axial direction; and The second driving mechanism is configured to drive the divider to move closer to and away from the transport track in the lateral direction.
2. The sample processing device according to claim 1, characterized in that: The divider is configured to clamp the plurality of samples when located at an initial position, and is configured to move in the lateral direction in a direction close to the transport track so that the plurality of clamping members simultaneously move in a direction close to the transport track to respectively clamp the plurality of samples simultaneously; The divider clamping the multiple samples is configured to be movable in the axial direction to simultaneously move the multiple samples arranged at the preset interval along the transfer track, the divider is configured to move away from the transfer track in the lateral direction to release the multiple samples, and the divider is configured to move along the axial direction to return to the initial position after releasing the multiple samples.
3. The sample processing device according to claim 1, characterized in that: The plurality of interposing members are arranged spaced apart from each other in the axial direction.
4. The sample processing device according to claim 3, characterized in that: The plurality of interposing members are arranged at equal intervals in the axial direction.
5. The sample processing device according to claim 3, characterized in that: The intervals between adjacent clamping members among the plurality of clamping members are adjustable.
6. The sample processing device according to claim 3, characterized in that: Each of the clamping members comprises a strip-shaped main body extending in a longitudinal direction and a clamping portion located at a lower end of the strip-shaped main body and connected to the main body, wherein the longitudinal direction is perpendicular to both the axial direction and the transverse direction; During the process of the sample being transported by the transfer track, the sample includes an upper portion located above the transfer track and a lower portion located below the transfer track, the upper portion of the transfer track and the lower portion of the transfer track are opposite to each other in the longitudinal direction, and the length of the lower portion in the longitudinal direction is greater than the length of the upper portion in the longitudinal direction; The clamping portion is located below the transport track in the longitudinal direction to clamp a lower portion of the sample.
7. The sample processing device according to claim 6, characterized in that: The transmission track comprises a first bearing plate and a second bearing plate both extending along the axial direction, and a gap sandwiched between the first bearing plate and the second bearing plate and extending along the axial direction, the first bearing plate having a first track bearing surface facing upwards, and the second bearing plate having a second track bearing surface facing upwards; During the process of the sample being transported by the transport track, the sample comprises a main body and an end connected to the main body, the main body and the end are arranged in the longitudinal direction, and the orthographic projection of the main body on a plane perpendicular to the longitudinal direction is located within the orthographic projection of the end on a plane perpendicular to the longitudinal direction; the main body has a radial dimension perpendicular to the longitudinal direction, and the end has a radial dimension perpendicular to the longitudinal direction; The width of the gap is smaller than the radial dimension of an end of the sample and larger than the radial dimension of a main part of the sample. The main part of the sample is clamped in the gap, and the end of the sample is supported on the first rail bearing surface and the second rail bearing surface; the end of the sample is the upper part, and the main part of the sample is the lower part.
8. The sample processing device according to claim 6, characterized in that: The clamping portion is U-shaped, and the U-shaped opening faces the transmission track. The U-shaped clamping portion has side walls located on both sides of the opening, and the side walls located on both sides of the opening are respectively a first side wall and a second side wall; there is a gap between adjacent side walls of two adjacent clamping portions, and the gap between two adjacent clamping members in the axial direction refers to the gap between adjacent side walls of two adjacent clamping portions.
9. The sample processing device according to claim 8, characterized in that: A surface of the first side wall facing the second side wall and a surface of the second side wall facing the first side wall are both curved surfaces.
10. The sample processing device according to any one of claims 1 to 9, characterized in that: The sample processing device comprises a plurality of the dividers, wherein the plurality of the dividers comprises a first divider and a second divider arranged at intervals in the axial direction; the first divider and the second divider both have the plurality of clamping members; The sample processing device further comprises an information collection area and a sample information collection device, a part of the transmission track is located in the information collection area, the sample information collection device is located in the information collection area and is configured to collect information of the sample transmitted to the information collection area; In the axial direction, the second divider is located on a side of the first divider close to the information collection area; The first divider is configured to move along the axial direction to the information collection position corresponding to the sample information collection device in the information collection area to move the plurality of samples arranged at the preset intervals clamped by the first divider along the transmission track to the sample information collection device, and the plurality of samples are arranged at the preset intervals in the sample information collection device; the second driving mechanism is configured to drive the first divider to move away from the transmission track in the transverse direction after the first divider transfers the plurality of samples to the sample information collection device, and then the first driving mechanism is configured to drive the first divider to move away from the second divider along the axial direction; The second divider is configured to move along the axial direction to the information collection position to clamp the multiple samples arranged at the preset interval in the sample information collection device after the information collection is completed and the first divider leaves the information collection position, and is configured to be movable along the axial direction to move the multiple samples it clamps.
11. The sample processing device according to claim 10, characterized in that: The sample information collection device comprises a sample clamping assembly, the sample clamping assembly comprises a plurality of groups of clamping mechanisms arranged in the axial direction, adjacent groups of the clamping mechanisms are spaced apart by the preset spacing in the axial direction, each group of the clamping mechanisms has a receiving space, the first spacer releases each of the samples to the receiving space correspondingly, and each group of the clamping mechanisms is configured to clamp one sample from the first spacer; The transmission track comprises a first carrier plate and a second carrier plate both extending along the axial direction, and a gap sandwiched between the first carrier plate and the second carrier plate and extending along the axial direction; in a process in which the plurality of samples are moved along the transmission track under the clamping of the first divider, the plurality of samples are sandwiched in the gap; Orthographic projections of the plurality of clamping mechanisms in a plane defined by the axial direction and the lateral direction at least partially overlap with orthographic projections of the slits of the transfer track in the plane.
12. The sample processing device according to any one of claims 1 to 9 and 11, characterized in that: The sample includes a nucleic acid detection sampling tube; the main body of the sample contains a tube body containing a substance to be detected, the end of the sample is a tube cover for sealing the tube body, the axial length of the tube body of the sample is greater than the axial length of the tube cover of the sample, and the main body of the sample is cylindrical in shape.