Pharmaceutical intermediate synthesizer

Abstract

The utility model relates to a medicine intermediate synthesis device which comprises a stirring synthesis box, the upper surface of the stirring synthesis box is fixedly communicated with a filter box, the inner wall of the filter box is provided with a vibration screen, the left side face of the filter box is fixedly communicated with a communication plate, and the left side face of the stirring synthesis box is fixedly connected with a running-in smashing box. The left end of the communicating plate fixedly communicates with the upper surface of the running-in smashing box, and two running-in rolling wheels are installed on the inner wall of the running-in smashing box. According to the device, a stirring rod is driven by a second driving motor, raw materials added into the device can be stirred and mixed to form the medical intermediate, particles or fragments in the raw materials can be screened out through an arranged vibration screen in the raw material adding process, the particles or fragments are ground through two arranged grinding-in rollers, and the grinding-in effect is good. And the powder is re-added into the device for mixing through the suction pump under the cooperation of the first connecting pipe and the second connecting pipe.

Description

Technical Field

[0001] The utility model relates to the field of medicine, in particular to a pharmaceutical intermediate synthesis device. Background Art

[0002] The so-called pharmaceutical intermediates are actually some chemical raw materials or chemical products used in the process of drug synthesis. This kind of chemical product does not require a drug production license and can be produced in an ordinary chemical plant. As long as it reaches a certain level, it can be used in drug synthesis.

[0003] The Chinese patent with publication number CN218249967U discloses a pharmaceutical intermediate synthesis device, which relates to the technical field of synthesis devices; and the utility model includes: a mixing box, a cover plate is closed on the upper side of the mixing box, and the upper side of the cover plate is fixedly connected to the feed port, the middle end of the lower side of the mixing box is fixedly connected to the discharge port, and the upper side of the middle end of the cover plate is fixedly connected to the motor, the motor output shaft is fixedly connected to the stirring rod, and the lower end of the stirring rod is inserted in the mixing box, and a filtering mechanism is arranged on the outer side of the upper end of the stirring rod, and the filtering mechanism includes a screening unit, a fixed ring plate, a clamping unit, a moving unit, a pushing unit, a connecting plate and a crushing unit. However, there are still some shortcomings in the above patents. In the process of synthesizing pharmaceutical intermediates, various raw materials must be stirred and mixed. However, if some raw materials are not crushed thoroughly during the mixing process, particles or fragments are likely to appear, resulting in uneven mixing. For this reason, we propose a pharmaceutical intermediate synthesis device to solve the above problems. Utility Model Content

[0004] 1. Technical issues to be resolved

[0005] In order to solve the above problems in the prior art, the utility model provides a pharmaceutical intermediate synthesis device.

[0006] (II) Technical solution

[0007] In order to achieve the above-mentioned purpose, the main technical solutions adopted by the utility model include:

[0008] A pharmaceutical intermediate synthesis device comprises a stirring synthesis box, the upper surface of which is fixedly connected to a filter box, the inner wall of which is installed with a vibrating screen, the left side of which is fixedly connected to a connecting plate, the left side of which is fixedly connected to a running-in and crushing box, the left end of which is fixedly connected to the upper surface of the running-in and crushing box, two running-in rollers are installed on the inner wall of the running-in and crushing box, the front end of one of the running-in rollers is fixedly connected to a first driving motor, the bottom end of which is fixedly connected to a first connecting pipe, the left side of which is fixedly connected to a suction pump, the left end of which is fixedly connected to an input end of the suction pump, the output end of which is fixedly connected to a second connecting pipe, and the top end of the second connecting pipe is fixedly connected to the upper surface of the filter box.

[0009] A stirring rod is installed inside the stirring synthesis box, and a second driving motor is fixedly connected to the bottom end of the stirring rod.

[0010] The upper surface of the filter box is fixedly connected with an injection cylinder, and a sealing cover is placed above the injection cylinder.

[0011] A protection frame is fixedly connected to the front of the running-in and crushing box, and a heat dissipation window is provided on the front of the protection frame.

[0012] A sealing door is hingedly connected to the right side of the mixing and synthesizing box through a hinge, and a control panel is fixedly connected to the front side of the mixing and synthesizing box.

[0013] The bottom surface of the mixing and synthesis box is fixedly connected with a plurality of supporting legs, and the bottom end of each supporting leg is fixedly connected with an anti-skid pad.

[0014] (III) Beneficial effects

[0015] The beneficial effects of the utility model are as follows: the pharmaceutical intermediate synthesis device can stir and mix the raw materials added into the device by driving the stirring rod through the second driving motor provided in the device, so as to mix them into pharmaceutical intermediates, and in the process of adding the raw materials, the particles or fragments in the raw materials can be screened out by the vibration screen provided, and they are ground into powder by two running-in rollers provided, and are re-added to the device for mixing by the suction pump provided in cooperation with the first connecting pipe and the second connecting pipe. Therefore, the device effectively solves the problem that in the existing device, if some raw materials are not crushed thoroughly enough during the mixing process, particles or fragments are likely to appear, resulting in uneven mixing. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] Figure 1 It is a schematic diagram of the three-dimensional structure of a pharmaceutical intermediate synthesis device;

[0017] Figure 2It is a schematic diagram of the cross-sectional structure of a pharmaceutical intermediate synthesis device;

[0018] Figure 3 It is a schematic diagram of the top-sectional structure of a pharmaceutical intermediate synthesis device;

[0019] Figure 4 It is a rear view structural schematic diagram of a pharmaceutical intermediate synthesis device;

[0020] [Description of Reference Numerals]

[0021] In the figure: 1. mixing and synthesis box; 2. connecting plate; 3. protection frame; 4. suction pump; 5. heat dissipation window; 6. first connecting pipe; 7. running-in crushing box; 8. control panel; 9. supporting leg; 10. second drive motor; 11. anti-skid pad; 12. second connecting pipe; 13. sealing cover; 14. injection barrel; 15. filter box; 16. running-in roller; 17. stirring rod; 18. vibrating screen; 19. first drive motor; 20. sealing door. DETAILED DESCRIPTION

[0022] In order to better explain the present invention and facilitate understanding, the present invention is described in detail below through specific implementation modes in conjunction with the accompanying drawings.

[0023] Please refer to Figures 1 to 4As shown, a pharmaceutical intermediate synthesis device of the utility model comprises a stirring synthesis box 1, the upper surface of the stirring synthesis box 1 is fixedly connected to a filter box 15, the inner wall of the filter box 15 is installed with a vibrating screen 18, the left side of the filter box 15 is fixedly connected to a connecting plate 2, the left side of the stirring synthesis box 1 is fixedly connected to a running-in crushing box 7, the left end of the connecting plate 2 is fixedly connected to the upper surface of the running-in crushing box 7, two running-in rollers 16 are installed on the inner wall of the running-in crushing box 7, the front end of one of the running-in rollers 16 is fixedly connected to a first driving motor 19, the bottom end of the running-in crushing box 7 is fixedly connected to a first connecting pipe 6, the left side of the running-in crushing box 7 is fixedly connected to a suction pump 4, the left end of the first connecting pipe 6 is fixedly connected to the input end of the suction pump 4, and the output end of the suction pump 4 is fixedly connected to The second connecting pipe 12, the top end of the second connecting pipe 12 is fixedly connected to the upper surface of the filter box 15, and the stirring rod 17 is driven by the second driving motor 10 provided in the device, so that the raw materials added to the device can be stirred and mixed, so as to be mixed into a pharmaceutical intermediate, and in the process of adding raw materials, the particles or fragments in the raw materials can be screened out by the vibrating screen 18, and they are ground by the two running-in rollers 16 to become powder, and are added back into the device for mixing by the suction pump 4 with the cooperation of the first connecting pipe 6 and the second connecting pipe 12. Therefore, the device effectively solves the problem that if some raw materials are not crushed thoroughly enough during the mixing process of the existing device, particles or fragments are likely to appear, resulting in uneven mixing. In the actual implementation process, when using this pharmaceutical intermediate synthesis device, first the staff will place the device in a suitable position, then pour the various raw materials to be mixed into the filter box 15 through the injection barrel 14, and vibrate and screen them by starting the vibrating screen 18 in the device, and at the same time start the second drive motor 10 in the device to drive the stirring rod 17 to mix and stir the filtered raw materials, then start the first drive motor 19 in the device to drive the two running-in rollers 16 to rotate, so that the filtered particles or fragments can be run-in, and then start the suction pump 4 in the device, with the cooperation of the first connecting pipe 6 and the second connecting pipe 12, the run-in raw materials are drawn into the device for re-mixing and stirring, and finally the worker opens the sealing door 20 to take out the mixed pharmaceutical intermediate.

[0024] Optionally, a stirring rod 17 is installed inside the stirring and synthesizing box 1, and the bottom end of the stirring rod 17 is fixedly connected to the second drive motor 10. In the actual implementation process, the stirring rod 17 is driven to rotate by the second drive motor 10, so that the raw materials added to the stirring and synthesizing box 1 can be evenly stirred and mixed.

[0025] Optionally, the upper surface of the filter box 15 is fixedly connected to a material injection barrel 14, and a sealing cover 13 is placed above the material injection barrel 14. In the actual implementation process, the material injection barrel 14 can be used to conveniently put various raw materials into the device, and the sealing cover 13 can prevent the vibration screen 18 from vibrating and splashing the raw materials when in use.

[0026] Optionally, a protection frame 3 is fixedly connected to the front of the run-in crushing box 7, and a heat dissipation window 5 is provided on the front of the protection frame 3. In the actual implementation process, the heat dissipation window 5 can be used to ventilate and dissipate heat for the first drive motor 19.

[0027] Optionally, a sealed door 20 is hingedly connected to the right side of the mixing and synthesizing box 1, and a control panel 8 is fixedly connected to the front of the mixing and synthesizing box 1. In the actual implementation process, by opening the sealed door 20, it is convenient for the staff to take out the raw materials in the box, and through the control panel 8 provided, it is convenient to control various electrical components in the device.

[0028] Optionally, a plurality of support legs 9 are fixedly connected to the bottom surface of the mixing and synthesis box 1, and a non-slip pad 11 is fixedly connected to the bottom end of each support leg 9. In the actual implementation process, the stability of the device during operation is guaranteed.

[0029] The above shows and describes the basic principle, main features and advantages of the utility model, and the standard parts used in the utility model can be purchased from the market, special-shaped parts can be customized according to the description and the drawings, and the specific connection methods of each part adopt mature conventional means such as bolts, rivets, welding, etc. in the prior art. Machinery, parts and equipment all adopt conventional models in the prior art, and the circuit connection adopts the conventional connection method in the prior art, which will not be described in detail here.

[0030] The above description is only an embodiment of the present invention, and does not limit the patent scope of the present invention. Any equivalent transformations made using the contents of the specification and drawings of the present invention, or directly or indirectly applied in the relevant technical field, are also included in the patent protection scope of the present invention.

Claims

1. A pharmaceutical intermediate synthesis device, comprising a stirring synthesis box (1), characterized in that: The upper surface of the mixing and synthesizing box (1) is fixedly connected to a filter box (15), the inner wall of the filter box (15) is installed with a vibrating screen (18), the left side of the filter box (15) is fixedly connected to a connecting plate (2), the left side of the mixing and synthesizing box (1) is fixedly connected to a running-in and crushing box (7), the left end of the connecting plate (2) is fixedly connected to the upper surface of the running-in and crushing box (7), and the inner wall of the running-in and crushing box (7) is installed with two running-in rollers (16), one of which is The front end of the running-in roller (16) is fixedly connected to a first drive motor (19); the bottom end of the running-in crushing box (7) is fixedly connected to a first connecting pipe (6); the left side of the running-in crushing box (7) is fixedly connected to a suction pump (4); the left end of the first connecting pipe (6) is fixedly connected to the input end of the suction pump (4); the output end of the suction pump (4) is fixedly connected to a second connecting pipe (12); the top end of the second connecting pipe (12) is fixedly connected to the upper surface of the filter box (15).

2. A pharmaceutical intermediate synthesis device as claimed in claim 1, characterized in that: A stirring rod (17) is installed inside the stirring synthesis box (1), and the bottom end of the stirring rod (17) is fixedly connected to a second driving motor (10).

3. A pharmaceutical intermediate synthesis device as claimed in claim 1, characterized in that: The upper surface of the filter box (15) is fixedly connected to a material injection cylinder (14), and a sealing cover (13) is placed above the material injection cylinder (14).

4. A pharmaceutical intermediate synthesis device as claimed in claim 1, characterized in that: The front of the run-in and crushing box (7) is fixedly connected to a protection frame (3), and the front of the protection frame (3) is provided with a heat dissipation window (5).

5. A pharmaceutical intermediate synthesis device as claimed in claim 1, characterized in that: The right side of the mixing and synthesizing box (1) is hinged with a sealed door (20) via a hinge, and the front side of the mixing and synthesizing box (1) is fixedly connected with a control panel (8).

6. A pharmaceutical intermediate synthesis device as claimed in claim 1, characterized in that: A plurality of support legs (9) are fixedly connected to the bottom surface of the mixing and synthesis box (1), and a non-slip pad (11) is fixedly connected to the bottom end of each support leg (9).

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