Image device capable of shielding X-ray radiation
By setting up an X-ray shielding film and radiation protection components in the imaging device of the laboratory X-ray photography all-in-one machine, the problem of X-ray radiation leakage in the prior art is solved, and higher experimental safety and flexible shielding design are achieved.
Patent Information
- Application Number
- CN202421198560.8
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-05-29
- Publication Date
- 2025-03-28
- Estimated Expiration
- 2034-05-29
AI Technical Summary
The existing laboratory X-ray all-in-one machine has radiation leakage problems, which endangers the safety of experimental operators.
An imaging device with its own shielding X-ray radiation is designed. An X-ray shielding film that can shield X-rays is set outside the dark box inside the housing, combined with radiation-proof components and modular assembly design, effective shielding of X-ray radiation is achieved.
It effectively reduces radiation leakage during experiments, improves experimental safety, and facilitates the replacement of X-ray shielding films of different thicknesses through modular design to meet different needs.
Smart Images
Figure CN222676240U_ABST
Abstract
Description
Technical Field
[0001] The utility model belongs to the technical field of optical imaging, and in particular relates to an imaging device capable of shielding X-ray radiation. Background Art
[0002] Animal in vivo imaging technology refers to the application of imaging methods to conduct qualitative and quantitative research on biological processes at the tissue, cell and molecular levels in vivo. The principle is to optically label target genes, cells, drug molecules, etc. and inject them into animals, and then use sensitive optical elements (such as CCD) to convert the light signals in the animal into electrical signals, and then convert them into image output. Compared with traditional in vitro imaging or cell culture, this powerful combination of technology platforms provides researchers with fast and effective experimental tools, effectively speeding up the decision-making time of animal experiments, and is the latest research method for studying disease mechanisms and exploring new treatment approaches.
[0003] At present, in vivo optical imaging is mainly divided into bioluminescence imaging (BLI) and fluorescence imaging (FLI). BLI connects the luciferase gene to the downstream of the promoter and stably integrates it into the cell chromosome, so that the luciferase is continuously expressed in the organism, and the substrate is injected to react with the expressed luciferase to emit light. FLI, on the other hand, uses fluorescent reporter genes (such as GFP, RFP) or fluorescent dyes such as Cyt and dyes for labeling, and the fluorescence generated by fluorescent proteins or dyes can form a fluorescent light source in the body.
[0004] In addition, there are many modes of in vivo optical imaging that can achieve multimodal imaging, such as upconversion fluorescence imaging, which is used for upconversion material research and development, biological imaging, anti-tumor drug delivery and photodynamic therapy; X-ray imaging, which is used for direct positioning imaging to better distinguish the internal structure of animals and greatly improve the accuracy of research; Cherenkov luminescence imaging, which is used for the research and development of radioactive tracers and the observation of tumor treatment.
[0005] Currently, X-ray imaging equipment is widely used in laboratory animal experiments. X-ray photography of living animals can clearly show the extent of lesions, which is of great significance to pathological research. However, the X-ray photography machines currently on the market for laboratories generally have radiation leakage problems, which poses a serious threat to experimental operators. Utility Model Content
[0006] The utility model aims to overcome the existing technical defects and provide an imaging device with self-shielding X-ray radiation, which can effectively reduce radiation leakage and improve experimental safety.
[0007] In order to solve the above technical problems, the utility model provides an imaging device with built-in X-ray radiation shielding, including a shell and a first dark box and a second dark box arranged in the shell from top to bottom and connected to each other vertically, the first dark box is provided with a camera module and a stage distributed vertically, the first dark box is also provided with a flat-panel detector located above the stage and movable along the X-axis direction, the interior or bottom of the second dark box is provided with an X-ray device located below the stage and irradiating toward the stage, the outer surfaces of the first dark box and the second dark box are wrapped with radiation protection components, the bottom of the first dark box and the top of the second dark box are provided with windows for X-rays to pass upward at the positions corresponding to the stage, the radiation protection components include a pressing plate and an X-ray shielding sheet adhered to the inner side of the pressing plate, the pressing plate is detachably fixed to the outer surfaces of the first dark box and the second dark box, and the X-ray shielding sheet is located between the pressing plate and the dark box.
[0008] Furthermore, the upper end of the shell is provided with an openable and closable door at a position corresponding to the first dark box, the first dark box is provided with an opening at a position corresponding to the door, and the interior or exterior of the door is provided with a radiation protection plate that can shield X-rays, the size of the radiation protection plate is larger than the size of the opening, and the projection of the radiation protection plate on the vertical plane covers the opening.
[0009] Furthermore, the imaging device with built-in X-ray radiation shielding also includes a turntable rotatably arranged on the upper end of the X-ray instrument and a stepper motor for driving the turntable to rotate, the turntable is provided with N through holes in a circular array, N is a positive integer greater than 2, and X-ray filters of different thicknesses or different materials are respectively provided at the N-1 through holes, and the turntable is rotated so that different X-ray filters or through holes are located above the emission hole of the X-ray instrument.
[0010] Furthermore, the turntable is provided with six through holes in a circular array, and aluminum sheets and / or copper sheets of different thicknesses are arranged in five of the through holes.
[0011] Furthermore, no X-ray filter is arranged in the first through hole, a high-purity aluminum sheet with a thickness of 0.5 mm is arranged in the second through hole, a high-purity aluminum sheet with a thickness of 1 mm is arranged in the third through hole, a high-purity aluminum sheet with a thickness of 0.5 mm and a copper sheet with a thickness of 0.06 mm are stacked in the fourth through hole, a high-purity aluminum sheet with a thickness of 0.5 mm and a copper sheet with a thickness of 0.1 mm are stacked in the fifth through hole, and a high-purity aluminum sheet with a thickness of 0.5 mm, a copper sheet with a thickness of 0.3 mm and a high-purity aluminum sheet with a thickness of 0.5 mm are stacked in sequence in the sixth through hole.
[0012] Furthermore, the imaging device with built-in X-ray radiation shielding also includes a movable slide for driving the flat-panel detector to move along the X-axis direction, the movable slide includes a horizontal guide rail, a lead screw rotatably arranged on the horizontal guide rail, and a motor transmission-connected to one end of the lead screw, a slider is slidably arranged on the horizontal guide rail, a lead screw nut is arranged on the lead screw, and one end of the flat-panel detector is connected to the slider and the lead screw nut.
[0013] Furthermore, the movable slide also includes a support plate, one end of which is connected to the slider and the lead screw nut, and the other end of which extends outwardly, and the flat panel detector is detachably mounted on the support plate.
[0014] Furthermore, the support plate is provided with a groove for placing the flat panel detector, and a slot for exposing the bottom of the flat panel detector is provided in the middle of the groove.
[0015] Furthermore, the camera module includes a camera disposed on the top of the first dark box and irradiating toward the stage, and a light source module disposed around the camera.
[0016] Furthermore, the imaging device with built-in X-ray radiation shielding also includes a vertical moving device for driving the stage to move along the Z-axis direction.
[0017] The utility model has the following beneficial effects:
[0018] In the utility model, an X-ray shielding sheet that can shield X-rays is directly arranged on the outside of the dark box inside the shell, which can effectively reduce radiation leakage during experiments, thereby reducing harm to operators and improving experimental safety; secondly, the X-ray shielding sheet is built-in and fixed inside the chassis, which is convenient for carrying and transporting the entire machine, and has a simple structure and easy installation; the X-ray shielding sheet is first glued to the inside of the pressure plate to form an anti-radiation component and then fixed to the dark box by screws, that is, a modular assembly design is formed between the anti-radiation component and the dark box, and the thickness of the X-ray shielding sheet on the inside of the pressure plate is replaceable, so that the purpose of replacing X-ray shielding sheets of different thicknesses can be achieved by disassembling the pressure plate.
[0019] Additional aspects and advantages of the present invention will be partially given in the following description, which will become apparent from the following description or be understood through the practice of the present invention. BRIEF DESCRIPTION OF THE DRAWINGS
[0020] The drawings described herein are used to provide a further understanding of the present invention, constitute a part of the present application, and do not constitute an improper limitation of the present invention. In the drawings:
[0021] Figure 1 is a schematic diagram of an imaging device in an embodiment;
[0022] Figure 2 is a front cross-sectional view of an imaging device in an embodiment;
[0023] Figure 3 for Figure 2 A is an enlarged schematic diagram;
[0024] Figure 4 for Figure 2 A magnified schematic diagram of B;
[0025] Figure 5 is a side sectional view of an imaging device in an embodiment;
[0026] Figure 6 for Figure 5 A magnified schematic diagram of middle C;
[0027] Figure 7 is a schematic diagram of the imaging device in the embodiment without the housing;
[0028] Figure 8 This is a schematic diagram of the second dark box and the X-ray apparatus after being assembled in the embodiment;
[0029] Fig. 9 Schematic diagram of an X-ray apparatus in an embodiment
[0030] Fig.10 Schematic diagram of the assembled flat panel detector and movable slide in the embodiment. DETAILED DESCRIPTION
[0031] In order to more fully understand the technical content of the present invention, the present invention will be further introduced and explained in conjunction with the accompanying drawings and specific embodiments below; it should be noted that descriptions such as "first" and "second" in the text are used to distinguish different components, etc., and do not represent the order of precedence, nor do they limit the "first" and "second" to different types.
[0032] The technical solutions in the embodiments of the utility model will be clearly and completely described below in conjunction with the drawings in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, rather than all of the embodiments; based on the embodiments of the utility model, all other embodiments obtained by those skilled in the art without making creative work are within the scope of protection of the utility model.
[0033] Example
[0034] like Figures 1 to 10As shown, the imaging device with self-shielding X-ray radiation shown in this embodiment includes a shell 1 and a first dark box 2 and a second dark box 3 arranged in the shell 1 from top to bottom and connected to each other from top to bottom. The first dark box 1 is provided with a camera module and a stage 4 distributed up and down, and the interior or bottom of the second dark box 3 is provided with an X-ray instrument 5 located below the stage 4 and irradiating toward the stage 4. The first dark box 1 is also provided with a flat-panel detector 6 located above the stage 4 and movable along the X-axis direction, so that the flat-panel detector 6 cooperates with the X-ray instrument to complete a linear scan of an object placed on the stage during the movement to obtain an X-ray image. The outer surfaces of the first dark box 2 and the second dark box 3 are wrapped with radiation protection components, and the bottom and The top of the second dark box 3 is provided with a window 20 for X-rays to pass upward at the position corresponding to the stage 4, that is, no radiation protection component is set at the window 20, and because the first dark box 2 and the second dark box 3 are connected up and down, after the outer surfaces of both are wrapped with the radiation protection component, the radiation protection component is also connected up and down, which will form an effective shielding structure for the two as a whole in the vertical direction; the radiation protection component includes a pressing plate 7 and an X-ray shielding film 8 pasted on the inner side of the pressing plate 7, the pressing plate 7 is detachably fixed to the outer surfaces of the first dark box 1 and the second dark box 2 by screws, and the X-ray shielding film 8 is located between the pressing plate 7 and the dark box to form a sandwich structure, sandwiching the X-ray shielding film 8 in the middle, so as to isolate the X-rays inside the dark box body from the outside.
[0035] In the above, an X-ray shielding sheet that can shield X-rays is directly arranged outside the dark box inside the shell, which can effectively reduce radiation leakage during the experiment, thereby reducing harm to operators and improving experimental safety; secondly, the X-ray shielding sheet is built-in and fixed inside the chassis, which is convenient for carrying and transporting the whole machine, and has a simple structure and easy installation; the X-ray shielding sheet is first glued to the inside of the pressure plate to form an anti-radiation component and then fixed to the dark box by screws, that is, a modular assembly design is formed between the anti-radiation component and the dark box, and the thickness of the X-ray shielding sheet on the inside of the pressure plate is replaceable, so that the purpose of replacing X-ray shielding sheets of different thicknesses can be achieved by disassembling the pressure plate.
[0036] In one embodiment, a rotatable door 21 is provided at the upper end of the shell 1 at a position corresponding to the lower end of the first dark box 2, and an opening 22 is provided in the first dark box 2 at a position corresponding to the door 21, that is, no radiation protection component is provided at the opening 22. In order to shield the opening 22, a radiation protection plate 23 that can shield X-rays is provided on the inside of the door 21. The size of the radiation protection plate 23 is larger than the size of the opening 22, and the projection of the radiation protection plate 23 on the vertical plane can effectively cover the opening 22, so that the radiation protection plate 23 on the door 21 is used to form a shielding structure at the opening. It can be understood that a radiation protection component can also be provided on the outside of the door to form a shielding structure, which is the same as the shielding structure of the first dark box and the second dark box, but such a setting will slightly affect the aesthetics of the entire device, so it is preferred to directly provide a radiation protection plate inside the door 21.
[0037] In one embodiment, if Fig. 9 As shown, the imaging device with built-in X-ray radiation shielding also includes a turntable 51 rotatably arranged on the upper end of the X-ray instrument 5 and a stepper motor 52 for driving the turntable 51 to rotate. The turntable 51 is provided with N through holes 53 in a circular array, N is a positive integer greater than 2, and N-1 through holes are respectively provided with X-ray filters 54 of different thicknesses or different materials. By rotating the turntable 51 so that different X-ray filters 54 or through holes 53 are located above the emission hole of the X-ray instrument 5, according to the imaging conditions required for different imaging objects, the corresponding X-ray filter 54 on the turntable is selected to filter the X-rays or the through holes are used not to filter the X-rays.
[0038] Preferably, a driving gear 55 is provided on the rotating shaft of the stepping motor 52 , and gear teeth meshing with the driving gear 55 are provided on the outer periphery of the rotating disk 51 .
[0039] In one embodiment, if Fig. 9 As shown, six through holes 53 are provided on the turntable 51 in a circular array; wherein, the first through hole is not provided with an X-ray filter, and is kept in a through hole shape, and is used for imaging low-voltage, low-contrast samples; a high-purity aluminum sheet with a thickness of 0.5 mm is provided in the second through hole, and is used for imaging low-contrast samples; a high-purity aluminum sheet with a thickness of 1 mm is provided in the third through hole, and is used for imaging soft tissue (fat analysis) samples; a high-purity aluminum sheet with a thickness of 0.5 mm and a copper sheet with a thickness of 0.06 mm are stacked up and down in the fourth through hole, and are used for standard scanning; a high-purity aluminum sheet with a thickness of 0.5 mm and a copper sheet with a thickness of 0.1 mm are stacked up and down in the fifth through hole, and are used for imaging high-voltage, high-density samples; a high-purity aluminum sheet with a thickness of 0.5 mm, a copper sheet with a thickness of 0.3 mm, and a high-purity aluminum sheet with a thickness of 0.5 mm are stacked up and down in the sixth through hole.
[0040] In one embodiment, if Fig.10As shown, the imaging device with built-in X-ray radiation shielding also includes a movable slide 60 for driving the flat-panel detector 6 to move along the X-axis direction. The movable slide includes a horizontal guide rail 61, a lead screw 62 rotatably arranged on the horizontal guide rail 61, and a motor 63 drivingly connected to one end of the lead screw 62. A slider 64 is slidably arranged on the horizontal guide rail 61, and a lead screw nut 65 is arranged on the lead screw 62. One end of the flat-panel detector 6 is connected to the slider 64 and the lead screw nut 65, so that the flat-panel detector 6 is driven to move back and forth along the horizontal guide rail 61 by using the movable slide.
[0041] As a preference, Fig.10 As shown, the movable slide 60 also includes a support plate 66, one end of which is connected to the slider 64 and the lead screw nut 65, and the other end extends outward. The flat-panel detector 6 is detachably mounted on the support plate 66 by screws, and the support plate 66 is used to support the flat-panel detector to avoid damage to one end of the flat-panel detector due to stress and difficulty in installation and connection.
[0042] As a preference, Fig.10 As shown, a groove 67 for placing the flat panel detector 6 is provided on the support plate 66 , and a slot 68 for exposing the bottom of the flat panel detector 6 is provided in the middle of the groove 67 .
[0043] In one embodiment, if Figure 3 As shown, the camera module includes a camera 91 disposed on the top of the first dark box 2 and irradiating toward the stage 4, and a light source module 92 disposed around the camera 91, and the light source module 92 provides light when the camera is shooting.
[0044] In one embodiment, if Figure 3-7 As shown, an opening is also provided at the top of the first dark box 2, and the camera module is fixed at the top opening of the first dark box 2 by a fixing plate 93. The size of the fixing plate 93 is larger than the top opening size of the first dark box 2 and covers the opening, and the surface of the fixing plate 93 is also provided with a radiation protection component. The size of the radiation protection component is larger than the top opening size of the first dark box 2 and covers the opening, that is, the radiation protection component arranged on the fixing plate 93 can effectively shield the top opening of the first dark box 2.
[0045] In one embodiment, if Figure 5 As shown, the imaging device further includes a vertical moving device 40 for driving the stage 4 to move along the Z-axis direction.
[0046] In other embodiments, the vertical moving device may adopt a screw drive mechanism, or may also adopt a belt drive mechanism or a cylinder drive mechanism, etc. The screw drive mechanism, the belt drive mechanism and the cylinder drive mechanism are all conventional drive mechanisms.
[0047] In other embodiments, the X-ray shielding sheet and the radiation protection plate are preferably made of lead sheet; of course, the X-ray shielding sheet and the radiation protection plate can also be made of other shielding materials that can shield X-rays.
[0048] The technical solutions provided by the embodiments of the present invention are introduced in detail above. Specific examples are used in this article to illustrate the principles and implementation methods of the embodiments of the present invention. The description of the above embodiments is only applicable to help understand the principles of the embodiments of the present invention. At the same time, for those skilled in the art, according to the embodiments of the present invention, there will be changes in the specific implementation methods and application scopes. In summary, the content of this specification should not be understood as a limitation on the present invention.
Claims
1. An imaging device with self-shielding X-ray radiation, comprising a housing and a first dark box and a second dark box arranged in the housing from top to bottom and connected to each other vertically, wherein the first dark box is provided with a camera module and a stage arranged vertically and distributedly, the first dark box is also provided with a flat panel detector located above the stage and movable along the X-axis direction, and the interior or bottom of the second dark box is provided with an X-ray instrument located below the stage and irradiating toward the stage, characterized in that: The exterior of the first dark box and the second dark box is wrapped with a radiation protection component. The bottom of the first dark box and the top of the second dark box are provided with windows for X-rays to pass upward at the positions corresponding to the worktables. The radiation protection component includes a pressure plate and an X-ray shielding film adhered to the inner side of the pressure plate. The pressure plate is detachably fixed to the exterior of the first dark box and the second dark box, and the X-ray shielding film is located between the pressure plate and the dark box.
2. The imaging device with self-shielding X-ray radiation according to claim 1, characterized in that: The upper end of the shell is provided with an openable and closable door at a position corresponding to the first dark box, the first dark box is provided with an opening at a position corresponding to the door, an anti-radiation plate is provided on the inside or outside of the door, the size of the anti-radiation plate is larger than the size of the opening, and the projection of the anti-radiation plate on the vertical plane covers the opening.
3. The imaging device with self-shielding X-ray radiation according to claim 2, characterized in that: It also includes a turntable rotatably arranged at the upper end of the X-ray instrument and a stepper motor for driving the turntable to rotate, the turntable is provided with N through holes in a circular array, N is a positive integer greater than 2, and X-ray filters of different thicknesses or different materials are respectively provided at the N-1 through holes, and the turntable is rotated so that different X-ray filters or through holes are located above the emission hole of the X-ray instrument.
4. The imaging device with self-shielding X-ray radiation according to claim 3, characterized in that: The turntable is provided with six through holes in a circular array, wherein aluminum sheets and / or copper sheets of different thicknesses are arranged in five of the through holes.
5. The imaging device with self-shielding X-ray radiation according to claim 4, characterized in that: No X-ray filter is set in the first through hole, a high-purity aluminum sheet with a thickness of 0.5 mm is set in the second through hole, a high-purity aluminum sheet with a thickness of 1 mm is set in the third through hole, a high-purity aluminum sheet with a thickness of 0.5 mm and a copper sheet with a thickness of 0.06 mm are stacked in the fourth through hole, a high-purity aluminum sheet with a thickness of 0.5 mm and a copper sheet with a thickness of 0.1 mm are stacked in the fifth through hole, and a high-purity aluminum sheet with a thickness of 0.5 mm, a copper sheet with a thickness of 0.3 mm and a high-purity aluminum sheet with a thickness of 0.5 mm is stacked in sequence in the sixth through hole.
6. The imaging device with self-shielding X-ray radiation according to any one of claims 1 to 5, characterized in that: It also includes a movable slide for driving the flat-panel detector to move along the X-axis direction, the movable slide includes a horizontal guide rail, a lead screw rotatably arranged on the horizontal guide rail, and a motor transmission-connected to one end of the lead screw, a slider is slidably arranged on the horizontal guide rail, a lead screw nut is arranged on the lead screw, and one end of the flat-panel detector is connected to the slider and the lead screw nut.
7. The imaging device with self-shielding X-ray radiation according to claim 6, characterized in that: The movable slide also includes a support plate, one end of which is connected to the slider and the lead screw nut, and the other end of which extends outwards. The flat panel detector is detachably mounted on the support plate.
8. The imaging device with self-shielding X-ray radiation according to claim 7, characterized in that: The support plate is provided with a groove for placing the flat panel detector, and the middle of the groove is provided with a slot for exposing the bottom of the flat panel detector.
9. The imaging device with self-shielding X-ray radiation according to any one of claims 1 to 5, characterized in that: The camera module comprises a camera which is arranged on the top of the first dark box and irradiates toward the stage, and a light source module which is arranged around the camera.
10. The imaging device with self-shielding X-ray radiation according to any one of claims 1 to 5, characterized in that: It also includes a vertical moving device for driving the stage to move along the Z-axis direction.