A special stirred reactor for drug production

Abstract

The utility model discloses a special stirring reactor for drug production, including a reactor, a thermometer, a screw rod, a connection box, a transmission mechanism, a fixed rod, a water spray mechanism, a stirring blade, a scraping mechanism, and a heating mechanism. The front side of the upper end of the reactor is fixedly connected with a thermometer, a screw rod is rotatably connected between the clamping plate and the upper part of the reactor, a transmission mechanism is arranged in the middle of the connection box, a water spray mechanism is arranged at the upper end of the fixed rod, a scraping mechanism is arranged at the upper side of the stirring blade, and a heating mechanism is arranged on the side wall of the reactor. The advantages of the utility model compared with the prior art are: the fixed rod drives the stirring blade to rotate and performs lifting and lowering motion at the same time, so that the drug mixing is more uniform and the discharging speed is faster; the water spray mechanism and the scraping mechanism are arranged to clean the inside of the reactor in coordination with the lifting and rotation of the fixed rod, thereby improving the cleaning efficiency and saving manpower.

Description

Technical Field

[0001] The utility model relates to the technical field of compost fermentation, in particular to a special stirring reactor for drug production. Background Art

[0002] Drug production refers to the use of research results in microbiology, biology, medicine, biochemistry, etc., from organisms, biological tissues, cells, body fluids, etc., and the comprehensive use of scientific principles and methods such as microbiology, chemistry, biochemistry, biotechnology, and pharmacy to manufacture a class of products used for prevention, treatment, and diagnosis. Biological drug raw materials are mainly natural biological materials, including microorganisms, human bodies, animals, plants, marine organisms, etc. Usually, stirred reactors are required for mixed drug production in the drug production process. With the development of biotechnology, purposefully artificially produced biological raw materials have become the main source of current biopharmaceutical raw materials.

[0003] A pharmaceutical stirring reactor described in announcement number CN219209933U can reduce the resistance of the utility model when stirring liquid or powder and liquid synthesis by setting a stirring structure with stirring holes, reduce the energy consumption of the device, and improve the stirring efficiency. By setting the bottom of the reactor body into a funnel shape with an isolation frame, it can ensure fast and smooth discharge, and the stirred medicine (powder-liquid synthesis medicine raw material) is not easy to block the discharge outlet or pipeline. However, the prior art still has defects:

[0004] 1. The prior art sets stirring holes on the stirring blades, which reduces resistance and energy consumption, but also reduces thrust, so that the vortex speed formed by the liquid medicine is slow, the stirring and mixing is uneven, and the discharge speed is reduced.

[0005] 2. Since drug mixing reactions usually require a certain temperature, the prior art does not have a heating and temperature control device, which is not conducive to the full reaction of the drug and is not practical. In addition, there is no cleaning device, and manual cleaning of the reactor is time-consuming and labor-intensive, which affects subsequent use. Utility Model Content

[0006] The technical problem to be solved by the utility model is to solve the above-mentioned problem and provide a special stirring reaction kettle for drug production.

[0007] A stirring reactor specially used for drug production comprises a reactor, wherein the front and rear ends and both sides of the lower part of the reactor are fixedly connected with support columns, a discharge pipe is inserted in the middle of the bottom of the reactor, a sealing cap 1 is sleeved on the lower end of the discharge pipe, a feed pipe is inserted in the front end of the upper part of the reactor, a sealing cap 2 is sleeved on the upper end of the feed pipe, a temperature gauge is arranged on one side of the front end of the upper part of the reactor, a temperature gauge is fixedly connected to the front side of the upper end of the reactor, an L-shaped clamping plate is fixedly connected to the rear end of the upper part of the reactor, a motor 1 is arranged on the upper end of the clamping plate, a screw rod is rotatably connected between the clamping plate and the upper part of the reactor, and the upper end of the screw rod is fixedly connected to the motor 1 A slider is sleeved on the upper end of the screw rod, a connecting rod is fixedly connected to the front side of the slider, a connecting box is arranged at the front end of the connecting rod, positioning rods are inserted at both ends of the connecting box, the lower end of the positioning rod is fixedly connected to the reactor, a block is arranged on the upper end of the positioning rod, a transmission mechanism is arranged in the middle of the connecting box, a fixed rod is rotatably connected to the middle part of the connecting box, the lower end of the fixed rod passes through the reactor and extends to the inside of the reactor, a water spraying mechanism is arranged on the upper end of the fixed rod, a plurality of evenly distributed stirring blades are fixedly connected to the lower end of the fixed rod, a scraping mechanism is arranged on the upper side of the stirring blade, and a heating mechanism is arranged on the side wall of the reactor.

[0008] As an improvement, the transmission mechanism includes a second motor fixedly connected to the middle of the front side of the outside of the connecting box, the rear end of the second motor is fixedly connected to a gear one and is arranged inside the connecting box, a lower end of the gear is meshed with a second gear, the second gear is sleeved on the outside of the fixed rod, a bearing is clamped in the middle of the bottom of the connecting box, and the fixed rod is inserted into the bearing.

[0009] As an improvement, the water spraying mechanism includes a water pump fixedly connected to the upper part of the connecting box, a water inlet groove is opened inside the fixing rod, the lower end of the water pump is connected to the water inlet groove, and water spraying holes are opened on both sides of the lower part of the curved wall of the fixing rod.

[0010] As an improvement, the scraping mechanism includes support rods fixedly connected to both sides of the lower part of the curved wall of the fixed rod, and an annular scraper is fixedly connected to one end of the support rod away from the fixed rod.

[0011] As an improvement, the heating mechanism includes a heating chamber opened inside the side wall of the reactor, and a plurality of evenly distributed annular electric heating tubes are longitudinally arranged inside the heating chamber.

[0012] Compared with the prior art, the advantages of the utility model are as follows: 1. A fixed rod is inserted in the middle of the upper part of the reactor, a connecting box is arranged at the upper end of the fixed rod, a transmission mechanism is arranged in the connecting box to drive the fixed rod to rotate, a stirring blade is arranged at the lower end of the fixed rod for rotating and stirring, a card plate is arranged at the rear end of the reactor to cooperate with the screw rod and the motor to drive the slider to move up and down, and the slider is connected to the connecting box through the connecting rod, so as to control the fixed rod to drive the stirring blade to do lifting movement, and cooperate with the rotation of the stirring blade, so that the medicine liquid can circulate in the horizontal and vertical directions at the same time, so that the medicine mixing is more uniform, the reaction is more thorough, and the discharge speed is faster.

[0013] 2. The utility model arranges a heating mechanism on the side wall of the reactor, and a heating chamber is provided. A plurality of annular electric heating tubes are provided inside the heating chamber to heat the inner wall of the reactor. The temperature inside the reactor can be more accurately controlled in conjunction with a thermometer and a temperature gauge, and can adapt to the temperature required for stirring and mixing different drugs, so that the reaction can be more thorough. At the same time, a scraping mechanism is provided to scrape off the residual adhesive on the inner wall of the reactor in conjunction with the lifting and rotation of the fixed rod. A water spraying mechanism is provided to provide a water inlet groove in the fixed rod, and water spraying holes are provided at the lower ends of both sides of the fixed rod. Clean water is pumped out through the water spraying holes by a water pump, and the inside of the reactor is cleaned in conjunction with the lifting and rotation of the fixed rod, thereby improving the cleaning efficiency and saving manpower. BRIEF DESCRIPTION OF THE DRAWINGS

[0014] Figure 1 The utility model is a three-dimensional schematic diagram of a special stirring reactor for drug production.

[0015] Figure 2 It is a partial structural stereogram of a stirring reactor specially used for drug production of the utility model.

[0016] Figure 3 The utility model is a side cross-sectional schematic diagram of a special stirred reactor for drug production.

[0017] Figure 4 It is an enlarged view of A of a stirring reactor specially used for drug production of the utility model.

[0018] Figure 5 It is an enlarged view B of a special stirred reactor for drug production of the utility model.

[0019] As shown in the figure: 1. Reactor; 2. Support column; 3. Discharge pipe; 4. Sealing cover 1; 5. Feed pipe; 6. Sealing cover 2; 7. Thermometer; 8. Thermometer; 9. Pallet; 10. Motor 1; 11. Screw; 12. Slider; 13. Connecting rod; 14. Connecting box; 15. Positioning rod; 16. Block; 17. Transmission mechanism; 17.1. Motor 2; 17.2. Gear 1; 17.3. Gear 2; 17.4. Bearing; 18. Fixing rod; 19. Water spray mechanism; 19.1. Water pump; 19.2. Water inlet trough; 19.3. Water spray hole; 20. Stirring blade; 21. Scraping mechanism; 21.1. Support rod; 21.2. Scraper; 22. Heating mechanism; 22.1. Heating bin; 22.2. Electric heating tube. DETAILED DESCRIPTION

[0020] The utility model is further described in detail below in conjunction with the accompanying drawings.

[0021] Combined with Figure 1 The utility model is provided with a cylindrical reactor 1, which is made of stainless steel. Four support columns 2 are arranged at the lower end of the reactor 1 for support. A discharge pipe 3 is inserted in the middle of the bottom of the reactor 1 and is sealed with a cover 1 4. A feed pipe 5 is inserted in the front end of the upper part of the reactor 1 and is sealed with a cover 2 6.

[0022] The upper rear end of the reactor 1 is rotatably connected with a screw rod 11 through an L-shaped card plate 9. A motor 10 is arranged on the upper end of the card plate 9. The motor 10 is a bidirectional reduction motor. The upper end of the screw rod 11 is fixedly connected to the output end of the motor 10. A slider 12 is sleeved on the upper end of the screw rod 11. The slider 12 is driven up and down by rotating the screw rod 11 through the motor 10. A connecting box 14 is arranged in front of the slider 12 through a connecting rod 13. Positioning rods 15 are inserted at both ends of the connecting box 14. The lower end of the positioning rod 15 is fixedly connected to the reactor 1 for fixing the connecting box 14 to prevent the connecting box 14 from rotating. A stopper 16 is arranged on the upper end of the positioning rod 15 for limiting. The connecting box 14 can be lifted and lowered by the connection between the connecting rod 13 and the slider 12.

[0023] The middle of the connecting box 14 is rotatably connected with a fixed rod 18, and extends through the inside of the reactor 1. A transmission mechanism 17 is arranged in the middle of the connecting box 14, including a motor 2 17.1 fixedly connected to the middle of the front side of the outside of the connecting box 14, a gear 17.2 is fixedly connected to the rear end of the motor 2 17.1 and arranged inside the connecting box 14, a gear 2 17.3 is meshed at the lower end of the gear 17.2, and the gear 2 17.3 is sleeved on the outside of the fixed rod 18, and the gear 1 17.2 and the gear 2 17.3 are both It is a bevel gear, and a bearing 17.4 is clamped in the middle of the bottom of the connecting box 14. A fixed rod 18 is inserted into the bearing 17.4 to facilitate the rotation of the fixed rod 18 in the connecting box 14. Three stirring blades 20 are fixedly connected to the lower end of the fixed rod 18, and each stirring blade 20 is inclined so that the whole is propeller-shaped, which is conducive to better driving the liquid medicine to form a vortex. The motor 2 17.1 rotates the gear 17.2 to drive the gear 2 17.3 and the fixed rod 18 to rotate and control the stirring blade 20 to stir the liquid medicine.

[0024] A heating mechanism 22 is provided on the side wall of the reactor 1, including a heating chamber 22.1 opened inside the side wall of the reactor 1, the heating chamber 22.1 is an annular interlayer, and 6 annular electric heating tubes 22.2 are provided inside the heating chamber 22.1 and are evenly distributed longitudinally, which can evenly heat the inner wall of the reactor 1, a thermometer 7 is provided on the front side of the upper end of the outside of the reactor 1, and a thermometer 8 is fixedly connected to the front side of the upper end of the inside of the reactor 1, which is used to detect the internal temperature of the reactor 1 and display it through the thermometer 7, so as to more accurately control the temperature during the drug reaction.

[0025] A water spray mechanism 19 is provided at the upper end of the fixed rod 18, including a water pump 19.1 fixedly connected to the upper part of the connection box 14, a water inlet groove 19.2 is provided inside the fixed rod 18, and the lower end of the water pump 19.1 is communicated with the water inlet groove 19.2, and water spray holes 19.3 are provided on both sides of the lower part of the curved wall of the fixed rod 18. The water pump 19.1 is connected to an external water pipe to extract clean water through the water inlet groove 19.2 and the water spray holes 19.3 to spray to both sides, and cooperate with the rotation and lifting of the fixed rod 18 to clean the side wall of the reactor 1, and a scraping mechanism 21 is provided on the upper side of the stirring blade 20, and an annular scraper 21.2 is connected between the water spray holes 19.3 at the lower ends of both sides of the fixed rod 18 and the stirring blade 20 through a support rod 21.1. The scraper 21.2 has the same diameter as the inner diameter of the reactor 1 and is made of plastic material so as not to damage the barrel wall, and cooperates with the rotation and lifting of the fixed rod 18 to scrape off the drug residues that are difficult to clean and adhere to the side wall of the reactor 1.

[0026] When the utility model is implemented, Figure 1As shown, open the cover 2 6 to put the medicine liquid into the reactor 1 through the feed pipe 5, cover the cover 2 6, start the motor 2 17.1 to drive the fixed rod 18 to rotate through the transmission mechanism 17.1, and use the stirring blade 20 to stir and mix the medicine liquid, start the motor 10 to control the fixed rod 18 to do the lifting movement through the screw rod 11 in cooperation with the slider 12, the connecting rod 13 and the connecting box 14, so that the mixing reaction is more uniform and rapid, and the internal heating temperature is accurately controlled according to the requirements of different drug reactions through the thermometer 7 in cooperation with the thermometer 8 and the heating mechanism 22. After the stirring is completed, open the cover 1 4 to discharge the medicine liquid through the discharge pipe 3, and start the water pump 19.1 to clean the inside of the reactor 1 through the water spraying mechanism 19 and the scraping mechanism 21 to cooperate with the rotation and lifting of the fixed rod 18.

[0027] The above description of the utility model and its implementation methods is not restrictive. The drawings show only one implementation method of the utility model, and the actual structure is not limited thereto. In short, if ordinary technicians in this field are inspired by it and design structural methods and embodiments similar to the technical solution without creativity without departing from the purpose of the invention of the utility model, they should all fall within the protection scope of the utility model.

Claims

1. A stirred reactor for drug production, comprising a reactor (1), characterized in that: The front and rear ends and both sides of the lower part of the reactor (1) are fixedly connected with support columns (2); a discharge pipe (3) is inserted in the middle of the bottom of the reactor (1); a sealing cover (4) is sleeved on the lower end of the discharge pipe; a feed pipe (5) is inserted in the front end of the upper part of the reactor (1); a sealing cover (6) is sleeved on the upper end of the feed pipe (5); a thermometer (7) is arranged on one side of the front end of the upper part of the reactor (1); a thermometer (8) is fixedly connected to the front side of the upper end of the reactor (1); an L-shaped card plate (9) is fixedly connected to the rear end of the upper part of the reactor (1); a motor (10) is arranged on the upper end of the card plate (9); a screw rod (11) is rotatably connected between the card plate (9) and the upper part of the reactor (1); the upper end of the screw rod (11) is fixedly connected to the motor (10); a slider (12) is sleeved on the upper end of the screw rod (11); the slider (12) 12) is fixedly connected to the front side with a connecting rod (13), a connecting box (14) is arranged at the front end of the connecting rod (13), positioning rods (15) are inserted at both ends of the connecting box (14), the lower end of the positioning rod (15) is fixedly connected to the reactor (1), the upper end of the positioning rod (15) is arranged with a stopper (16), a transmission mechanism (17) is arranged in the middle of the connecting box (14), a fixing rod (18) is rotatably connected to the middle of the connecting box (14), the lower end of the fixing rod (18) passes through the reactor (1) and extends into the interior of the reactor (1), a water spraying mechanism (19) is arranged at the upper end of the fixing rod (18), a plurality of uniformly distributed stirring blades (20) are fixedly connected to the lower end of the fixing rod (18), a scraping mechanism (21) is arranged on the upper side of the stirring blade (20), and a heating mechanism (22) is arranged on the side wall of the reactor (1).

2. A stirred reactor for drug production according to claim 1, characterized in that: The transmission mechanism (17) comprises a second motor (17.1) fixedly connected to the middle of the front side of the outside of the connection box (14); the rear end of the second motor (17.1) is fixedly connected to a first gear (17.2) and is arranged inside the connection box (14); the lower end of the first gear (17.2) is meshed with a second gear (17.3); the second gear (17.3) is sleeved on the outside of a fixing rod (18); a bearing (17.4) is clamped in the middle of the bottom of the connection box (14); and the fixing rod (18) is inserted into the inside of the bearing (17.4).

3. A stirred reactor for drug production according to claim 1, characterized in that: The water spray mechanism (19) comprises a water pump (19.1) fixedly connected to the upper part of the connection box (14); a water inlet groove (19.2) is provided inside the fixed rod (18); the lower end of the water pump (19.1) is connected to the water inlet groove (19.2); and water spray holes (19.3) are provided on both sides of the lower part of the curved wall of the fixed rod (18).

4. A stirred reactor for drug production according to claim 1, characterized in that: The scraping mechanism (21) comprises a support rod (21.1) fixedly connected to both sides of the lower part of the curved wall of the fixed rod (18); an annular scraper (21.2) is fixedly connected to one end of the support rod (21.1) away from the fixed rod (18).

5. A stirred reactor for drug production according to claim 1, characterized in that: The heating mechanism (22) comprises a heating chamber (22.1) opened inside the side wall of the reaction kettle (1), and a plurality of evenly distributed annular electric heating tubes (22.2) are longitudinally arranged inside the heating chamber (22.1).

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