Yeast high-throughput screening device

By designing the fit between the chimera tank and the chimera frame in the yeast high-throughput screening device and installing the compacting components, the problem of fermented substance leakage caused by the gap between the orifice plate and the bottom plate is solved, and a more efficient yeast screening effect is achieved.

CN222715345UActive Publication Date: 2025-04-04ZHENGZHOU YUANXIAO BIOTECHNOLOGY CO LTD

Patent Information

Application Number
CN202421332999.5
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-06-12
Publication Date
2025-04-04
Estimated Expiration
2034-06-12

AI Technical Summary

Technical Problem

In existing high-throughput yeast screening devices, there is a gap between the well plate and the base plate, causing the fermented substance to enter other screening chambers, affecting the screening efficiency.

Method used

A high-throughput yeast screening device is designed to prevent fermentation from entering other screening chambers through the gap between the orifice plate and the base plate by uniformly opening the screening chamber on the orifice plate body and cooperating with the meshing groove and the meshing frame. In addition, by installing the compression assembly, the motor drive gear and the insert plate are close to each other, so that the bottom plate and the top plate are closely attached to the orifice plate body, thereby further enhancing the fit tightness between the orifice plate and the bottom plate.

Benefits of technology

It effectively avoids fermentation substances entering other screening chambers through the gap between the orifice plate and the bottom plate, improves the efficiency and accuracy of fermentation, and ensures the high-throughput screening effect of yeast.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model discloses a high-throughput yeast screening device, comprising an orifice plate body, a bottom plate is provided at the bottom of the orifice plate body, a top plate is provided at the top of the orifice plate body, screening chambers are evenly opened on the orifice plate body, an embedding groove is provided at the bottom end of the outer wall of the screening chamber, an embedding frame is evenly installed at the top end of the bottom plate, the embedding frame is inserted into the inside of the embedding groove, the embedding frame is arranged in a mouth shape, the outer wall of the embedding frame is tightly attached to the inner wall of the embedding groove, and the inner side wall of the embedding frame is longitudinally flush with the inner side wall of the screening chamber; during work, the utility model is arranged that the screening chambers are evenly opened on the orifice plate body, the bottom of the inner wall of the screening chamber is provided with an embedding groove, the top end of the bottom plate is evenly installed with the embedding frame, the embedding frame is arranged in a mouth shape, the embedding frame can be embedded in the embedding groove, and the embedding groove and the embedding frame cooperate with each other to prevent the fermented material from entering other screening chambers through the gap between the orifice plate body and the bottom plate, thereby facilitating fermentation.
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Description

Technical Field

[0001] The utility model belongs to the technical field of yeast screening, in particular to a high-throughput yeast screening device. Background Art

[0002] According to the patent document with the authorization announcement number of "CN219730934U" and the invention name of "A high-throughput screening device for heat-resistant yeast", its specification states: In the actual application process of the heat-resistant yeast screening device, the fermented fermented material is first added to the screening chamber in the orifice plate for fermentation. During the fermentation process, the magnetic stirring device is started, and the magnetic stirring bar in the screening chamber is driven to rotate by the magnetic field, so as to achieve the stirring and mixing of the fermented material in the screening chamber, thereby ensuring the actual fermentation effect. Through the forty-eight screening chambers arranged in the orifice plate, a larger number of yeasts can be screened at a time, ensuring a higher screening efficiency of the yeast. In addition, the longitudinal marking grooves and transverse marking grooves opened in the horizontal and vertical directions of the edge of the orifice plate facilitate the positioning and marking of multiple screening chambers in the orifice plate, so as to facilitate the marking of yeast fermented in multiple screening chambers, facilitate the subsequent sampling of yeast, and avoid the phenomenon of sampling confusion. However, the following defects still exist:

[0003] During use, due to the gap between the orifice plate and the bottom plate, the fermented product may enter other screening chambers through the gap between the orifice plate and the bottom plate, thus affecting the screening. Utility Model Content

[0004] In view of the above situation, in order to overcome the defects of the prior art, the utility model provides a yeast high-throughput screening device, which effectively solves the problem that the gap between the well plate and the bottom plate may cause the fermentation product to enter other screening chambers.

[0005] To achieve the above-mentioned purpose, the utility model provides the following technical scheme: a yeast high-throughput screening device comprises a well plate body, a bottom plate is provided below the well plate body, a top plate is provided above the well plate body, screening chambers are evenly provided on the well plate body, an embedding groove is provided at the bottom end of the outer wall of the screening chamber, an embedding frame is evenly installed on the top of the bottom plate, the embedding frame is inserted into the inside of the embedding groove, the embedding frame is arranged in a mouth shape, the outer wall of the embedding frame is tightly attached to the inner wall of the embedding groove, the inner side wall of the embedding frame is longitudinally flush with the inner side wall of the screening chamber, air holes are evenly opened on the top plate, the screening chamber, the embedding frame and the air holes correspond to each other one by one, positioning grooves are symmetrically opened on both sides of the well plate body, slots are symmetrically opened on both sides of the bottom plate and both sides of the top plate, and clamping components are symmetrically installed on both sides of the well plate body.

[0006] Preferably, the clamping assembly comprises mounting boxes symmetrically arranged on both sides of the orifice plate body, a positioning block is fixedly mounted on one side of the mounting box close to the orifice plate body, and the positioning block is inserted into the interior of the positioning groove.

[0007] Preferably, the installation box has two plate slots symmetrically provided inside, tooth plates are slidably installed inside the plate slots, plug plates are installed at the upper and lower ends of the two tooth plates, and the two plug plates are respectively inserted into the slots of the bottom plate and the top plate.

[0008] Preferably, a gear installation groove is provided between the two plate grooves, a rotating gear is rotatably installed inside the gear installation groove, and the rotating gear is meshed with the two tooth plates.

[0009] Preferably, one side of the rotating gear is coaxially fixedly connected to the output shaft of the motor, and the motor is fixedly installed on the side wall of the installation box. When the motor is turned on, it drives the rotating gear to rotate, driving the upper and lower plug plates to approach each other, so that the bottom plate and the top plate are respectively tightly attached to the bottom wall and the top wall of the screening chamber.

[0010] Preferably, a magnetic stirrer is installed inside the screening chamber, and the bottom plate is placed on a clamping assembly, which is used to drive the magnetic stirrer for stirring.

[0011] Compared with the prior art, the beneficial effects of the utility model are:

[0012] During operation, screening chambers are evenly provided on the orifice plate body, a fitting groove is provided at the bottom of the inner wall of the screening chamber, and a fitting frame is evenly installed on the top of the bottom plate. The fitting frame is provided in a mouth shape, and the fitting frame can be embedded in the fitting groove. With the cooperation between the fitting groove and the fitting frame, the fermented material is prevented from entering other screening chambers through the gap between the orifice plate body and the bottom plate, so as to facilitate fermentation.

[0013] During operation, the installation boxes are installed on both sides of the orifice plate body, and the upper and lower plug plates are respectively inserted into the slots on the bottom plate and the top plate. The motor is turned on so that the upper and lower plug plates press the bottom plate and the top plate against the orifice plate body, thereby improving the tightness of the fit between the orifice plate body and the bottom plate, further preventing the fermented material from entering other screening chambers through the gap between the orifice plate body and the bottom plate, and facilitating fermentation. BRIEF DESCRIPTION OF THE DRAWINGS

[0014] The accompanying drawings are used to provide a further understanding of the present invention and constitute a part of the specification. They are used together with the embodiments of the present invention to explain the present invention and do not constitute a limitation to the present invention.

[0015] In the attached picture:

[0016] Figure 1 This is a schematic diagram of the structure of a yeast high-throughput screening device of the utility model;

[0017] Figure 2 This is a schematic diagram of the structure of the orifice plate body of the utility model;

[0018] Figure 3 This is a schematic diagram of the internal structure of the orifice plate body of the utility model;

[0019] Figure 4 It is a schematic diagram of the structure of the clamping assembly of the utility model.

[0020] In the figure: 1. orifice plate body; 2. bottom plate; 3. top plate; 4. screening chamber; 5. fitting groove; 6. fitting frame; 7. air vent; 8. positioning groove; 9. slot; 10. magnetic stirring device; 11. clamping assembly; 1101. installation box; 1102. positioning block; 1103. plate groove; 1104. tooth plate; 1105. plug plate; 1106. gear installation groove; 1107. rotating gear; 1108. motor. DETAILED DESCRIPTION

[0021] The technical solutions in the embodiments of the utility model will be clearly and completely described below in conjunction with the drawings in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, rather than all of the embodiments; based on the embodiments of the utility model, all other embodiments obtained by ordinary technicians in this field without making creative work are within the scope of protection of the utility model.

[0022] Embodiment 1, by Figure 1-4 The utility model relates to a high-throughput screening device for yeast, comprising a well plate body 1, a bottom plate 2 is provided below the well plate body 1, a top plate 3 is provided above the well plate body 1, screening chambers 4 are evenly provided on the well plate body 1, an embedding groove 5 is provided at the bottom end of the outer wall of the screening chamber 4, an embedding frame 6 is evenly installed on the top of the bottom plate 2, the embedding frame 6 is inserted into the embedding groove 5, the embedding frame 6 is arranged in a mouth shape, the outer wall of the embedding frame 6 is tightly attached to the inner wall of the embedding groove 5, the inner side wall of the embedding frame 6 is vertically flush with the inner side wall of the screening chamber 4, the top plate 3 is evenly provided with air holes 7, the screening chamber 4, the embedding frame 6 and the air holes are evenly provided. The three pores 7 correspond to each other one by one, positioning grooves 8 are symmetrically provided on both sides of the orifice plate body 1, slots 9 are symmetrically provided on both sides of the bottom plate 2 and both sides of the top plate 3, clamping components 11 are symmetrically installed on both sides of the orifice plate body 1, screening chambers 4 are evenly provided on the orifice plate body 1, and the bottom of the inner wall of the screening chamber 4 is provided with an embedding groove 5, and the top of the bottom plate 2 is evenly installed with an embedding frame 6, which is arranged in a mouth shape and can be embedded in the embedding groove 5. With the cooperation of the embedding groove 5 and the embedding frame 6, the fermented material is prevented from entering other screening chambers 4 through the gap between the orifice plate body 1 and the bottom plate 2, so as to facilitate fermentation.

[0023] The clamping assembly 11 includes an installation box 1101 symmetrically arranged on both sides of the orifice plate body 1, a positioning block 1102 is fixedly installed on one side of the installation box 1101 close to the orifice plate body 1, and the positioning block 1102 is inserted into the interior of the positioning groove 8, and two plate grooves 1103 are symmetrically provided inside the installation box 1101, and a tooth plate 1104 is slidably installed inside the plate groove 1103, and plug plates 1105 are respectively installed at the upper and lower ends of the two tooth plates 1104, and the two plug plates 1105 are respectively inserted into the slot 9 of the bottom plate 2 and the slot 9 of the top plate 3, and a gear installation groove 1106 is provided between the two plate grooves 1103, and a rotating gear 1107 is rotatably installed inside the gear installation groove 1106, and the rotating gear 1107 is meshed with the two tooth plates 1104, and the rotating gear 1107 is engaged with the two tooth plates 1104. One side is coaxially fixedly connected with the output shaft of motor 1108, and motor 1108 is fixedly installed on the side wall of installation box 1101. After motor 1108 is turned on, it drives rotating gear 1107 to rotate, and drives upper and lower plug plates 1105 to approach each other, so that bottom plate 2 and top plate 3 are respectively in close contact with the bottom wall and top wall of screening chamber 4. Installation box 1101 is installed on both sides of orifice plate body 1, and upper and lower plug plates 1105 are respectively inserted into slots 9 on bottom plate 2 and top plate 3. Turn on motor 1108 so that upper and lower plug plates 1105 press bottom plate 2 and top plate 3 against orifice plate body 1, thereby improving the tightness of fitting between orifice plate body 1 and bottom plate 2, and further preventing fermentation from entering other screening chambers 4 through the gap between orifice plate body 1 and bottom plate 2, so as to facilitate fermentation.

[0024] A magnetic stirring bar is installed inside the screening chamber 4, and the bottom plate 2 is placed on the pressing component 11, which is used to drive the magnetic stirring bar to stir.

[0025] Working principle: When working, first install the orifice plate body 1 on the bottom plate 2, so that each embedded frame 6 on the bottom plate 2 enters the embedded groove 5, and fills the fermented material to be fermented into each screening chamber 4. Since the embedded frame 6 cooperates with the embedded groove 5, the fermented material is prevented from entering other screening chambers 4 through the gap between the orifice plate body 1 and the bottom plate 2, which facilitates fermentation;

[0026] A top plate 3 is installed on the top of the orifice plate body 1. The air holes 7 on the top plate 3 are used for ventilation. A magnetic stirrer is placed inside the screening chamber 4. Then, installation boxes 1101 are installed on both sides of the orifice plate body 1. The positioning block 1102 is inserted into the positioning groove 8. The upper and lower plug plates 1105 are respectively inserted into the slots 9 on the same side of the bottom plate 2 and the top plate 3. The motor 1108 is turned on to rotate the rotating gear 1107. Since the two sides of the rotating gear 1107 and the two tooth plates 1104 are close to each other, the upper and lower plug plates 1105 press the bottom plate 2 and the top plate 3 against the orifice plate body 1, further preventing the fermented material from entering other screening chambers 4 through the gap between the orifice plate body 1 and the bottom plate 2, thereby facilitating fermentation.

[0027] The installed equipment is placed on the magnetic stirring device 10, and the magnetic stirring device 10 is turned on so that the magnetic stirring bar stirs the fermented material to facilitate fermentation.

Claims

1. A yeast high-throughput screening device, comprising a well plate body (1), characterized in that: A bottom plate (2) is provided below the orifice plate body (1), a top plate (3) is provided above the orifice plate body (1), screening chambers (4) are evenly provided on the orifice plate body (1), a fitting groove (5) is provided at the bottom end of the outer wall of the screening chamber (4), a fitting frame (6) is evenly installed at the top end of the bottom plate (2), the fitting frame (6) is inserted into the inside of the fitting groove (5), the fitting frame (6) is arranged in a mouth shape, and the outer wall of the fitting frame (6) and the inner wall of the fitting groove (5) are fitted together. The inner wall of the chimeric frame (6) is flush with the inner wall of the screening chamber (4) in the longitudinal direction. The top plate (3) is evenly provided with air holes (7). The screening chamber (4), the chimeric frame (6) and the air holes (7) correspond to each other one by one. Positioning grooves (8) are symmetrically provided on both sides of the orifice plate body (1). Slots (9) are symmetrically provided on both sides of the bottom plate (2) and both sides of the top plate (3). Pressing components (11) are symmetrically installed on both sides of the orifice plate body (1).

2. A yeast high-throughput screening device according to claim 1, characterized in that: The clamping assembly (11) comprises an installation box (1101) symmetrically arranged on both sides of the orifice plate body (1), and a positioning block (1102) is fixedly installed on one side of the installation box (1101) close to the orifice plate body (1), and the positioning block (1102) is inserted into the interior of the positioning groove (8).

3. A yeast high-throughput screening device according to claim 2, characterized in that: The installation box (1101) has two plate slots (1103) symmetrically formed inside, and tooth plates (1104) are slidably mounted inside the plate slots (1103). Insertion plates (1105) are respectively mounted at the upper and lower ends of the two tooth plates (1104), and the two insertion plates (1105) are respectively inserted into the slots (9) of the bottom plate (2) and the slots (9) of the top plate (3).

4. A yeast high-throughput screening device according to claim 3, characterized in that: A gear installation groove (1106) is provided between the two plate grooves (1103), a rotating gear (1107) is rotatably installed inside the gear installation groove (1106), and the rotating gear (1107) is meshed with the two tooth plates (1104).

5. A yeast high-throughput screening device according to claim 4, characterized in that: One side of the rotating gear (1107) is coaxially fixedly connected to the output shaft of the motor (1108). The motor (1108) is fixedly mounted on the side wall of the mounting box (1101). When the motor (1108) is turned on, it drives the rotating gear (1107) to rotate, thereby driving the upper and lower plug plates (1105) to approach each other, so that the bottom plate (2) and the top plate (3) are respectively in close contact with the bottom wall and the top wall of the screening chamber (4).

6. A yeast high-throughput screening device according to claim 1, characterized in that: A magnetic stirrer is installed inside the screening chamber (4), and the bottom plate (2) is placed on a pressing component (11), which is used to drive the magnetic stirrer to stir.

Citation Information

Patent Citations

  • Heat-resistant yeast high-throughput screening equipment

    CN219730934U

Cited By

  • A high throughput screening device

    CN224678026U