A device for cell ultrasound

Abstract

The utility model relates to the technical field of ultrasonic equipment, and provides a device for cell ultrasound. It includes: a base assembly, a platform assembly and a column assembly; wherein the base body of the base assembly is connected to the column body in the column assembly, and the slide groove of the column body is connected to the platform plate of the platform assembly; the base body is provided with a groove, and a chuck is provided in the groove; a through hole is provided on the platform plate, and the through hole is located in the center of the platform plate. The beneficial effect is that the device fixes the ultrasonic probe through the chuck in the groove of the base, and contacts the orifice plate containing cell tissue through the through hole, which solves the problem of the experimenter holding the probe to irradiate the orifice plate for a long time. In addition, the device is simple in design, easy to operate, and has excellent stability, which significantly improves the efficiency of cell ultrasonic treatment, effectively ensures the biological activity of cells, reduces the work intensity of the experimenter, and saves working time.

Description

Technical Field

[0001] The utility model relates to the technical field of ultrasonic equipment, in particular to a device used for cell ultrasound. Background Art

[0002] Ultrasound is a high-frequency sound wave that exceeds the human hearing threshold and usually exists in the form of pressure waves. In theory, ultrasound can replace certain external force stimulation and can produce micro-pressure on bones and surrounding tissues. Wolff's law shows that the formation and structure of bones are reconstructed with the magnitude and direction of external forces, and the physiological response and healing of bones can be affected by mechanical forces. Ultrasound can change the structure of cell membrane receptors, activate calcium ion channels, and cause calcium ions to flow into cells, leading to an increase in intracellular Ca+ concentration. The difference in ion concentration inside and outside the cell causes the transmembrane potential of different cell types to range from -10mv to 90mv. Changes in transmembrane potential can affect cell proliferation and differentiation, thereby promoting bone defect repair. Therefore, cell ultrasound has been widely used in regenerative medicine and bone tissue engineering.

[0003] When using existing scientific research instruments for cell ultrasound, in order to ensure sterility and fix the culture plate, the sterilized ultrasonic instrument is usually placed in a clean bench and the probe is fixed to the bottom of the well plate for ultrasound. The operation process is time-consuming and laborious. At the same time, the experimenter is prone to fatigue when holding the probe for a long time, and it is difficult to ensure accurate pressure on the bottom of the well plate, which affects the effect of ultrasound stimulation and reduces the accuracy of the experimental results.

[0004] In view of this, the present invention is proposed. Utility Model Content

[0005] The purpose of the utility model is to provide a device for cell ultrasound to solve the technical problems existing in the prior art.

[0006] To achieve the above-mentioned purpose, the technical solution adopted by the utility model is: a device for cell ultrasound, comprising: a base assembly, a platform assembly and a column assembly; wherein the base body of the base assembly is connected to the column body in the column assembly, and the slide groove of the column body is connected to the platform plate of the platform assembly;

[0007] The base body is provided with a groove, and a clamp is provided in the groove; the platform plate is provided with a through hole, and the through hole is located in the center of the platform plate.

[0008] In an optional embodiment, a first ultraviolet lamp and a second ultraviolet lamp are disposed on the base body, and the first ultraviolet lamp and the second ultraviolet lamp are respectively located on two sides of the groove.

[0009] In an optional embodiment, a plug interface and a switch are provided on one side of the base body.

[0010] In an optional embodiment, the platform plate is fixedly connected to the sliding bottom plate, one side of the sliding bottom plate is a sliding side plate, and the two ends of the sliding bottom plate are a sliding bottom plate and a sliding top plate.

[0011] In an optional embodiment, a knob that penetrates into the sliding groove is provided on the column body.

[0012] In an optional embodiment, the device further comprises a well plate, and a plurality of cell containers are arranged on the plate body of the well plate.

[0013] In an optional embodiment, the device further comprises an ultrasonic instrument, and the ultrasonic instrument leads to an ultrasonic probe via a connecting line.

[0014] In an optional embodiment, a pair of slots are provided on the ultrasonic probe.

[0015] In an optional embodiment, the device further comprises a lampshade assembly, and a lampshade body of the lampshade assembly is provided with a first avoidance groove and a second avoidance groove.

[0016] In an optional embodiment, the diameter of the cell container is smaller than the diameter of the through hole.

[0017] The beneficial effects of the utility model are:

[0018] The device fixes the ultrasonic probe through the chuck in the groove of the base, and contacts the well plate containing cell tissue through the through hole, which solves the problem of the experimenter holding the probe to irradiate the well plate for a long time. Before the experiment, the base, ultrasonic probe and well plate can be sterilized in a sterile lampshade to ensure that the cell tissue is not contaminated by the equipment as much as possible. The device has a simple design, convenient operation and excellent stability. It significantly improves the efficiency of cell ultrasonic treatment, effectively ensures the biological activity of cells, reduces the workload of experimenters, and saves working time. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] In order to more clearly illustrate the technical solutions in the embodiments of the present invention, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.

[0020] Figure 1 It is a schematic diagram of the overall structure (without lampshade installed) of a device for cell ultrasound provided in one embodiment of the utility model.

[0021] Figure 2 This is a schematic diagram of the overall structure (with a lampshade installed) of a device for cell ultrasound provided in one embodiment of the utility model.

[0022] Figure 3 This is a schematic diagram of the overall structure of a device for cell ultrasound provided in one embodiment of the utility model (without the orifice plate and the lampshade installed).

[0023] Figure 4 The present invention is a schematic structural diagram of a platform component in a device for cell ultrasound provided in one embodiment of the present invention.

[0024] Figure 5 The present invention is a schematic structural diagram of a base assembly and a column assembly in a device for cell ultrasound provided in one embodiment of the present invention.

[0025] Figure 6 The present invention is a schematic structural diagram of a lampshade assembly in a device for cell ultrasound provided in one embodiment of the present invention.

[0026] Figure 7 The present invention is a schematic diagram of the structure of an ultrasonic instrument in a device for cell ultrasound provided in one embodiment of the present invention.

[0027] Figure 8 This is a schematic diagram of the structure of a well plate in a device for cell ultrasound provided in one embodiment of the utility model.

[0028] Among them, the figures are marked as follows: 1-base assembly, 11-base body, 12-groove, 13-first ultraviolet lamp, 14-second ultraviolet lamp, 15-plug interface, 16-switch, 17-chuck; 2-platform assembly, 21-platform plate, 22-through hole, 23-limiting top plate, 24-sliding bottom plate, 25-sliding side plate, 26-limiting bottom plate; 3-column assembly, 31-column body, 32-slide groove, 33-knob; 4-hole plate, 41-plate body, 42-cell container; 5-ultrasonic instrument, 51-ultrasonic probe, 52-card slot; 6-lamp cover assembly, 61-lamp cover body, 62-first avoidance groove, 63-second avoidance groove. DETAILED DESCRIPTION

[0029] In order to make the technical problems, technical solutions and beneficial effects to be solved by the present invention more clearly understood, the present invention is further described in detail below in conjunction with the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are only used to explain the present invention and are not used to limit the present invention.

[0030] It should be noted that when a component is referred to as being "fixed on" or "disposed on" another component, it may be directly or indirectly located on the other component. When a component is referred to as being "connected to" another component, it may be directly or indirectly connected to the other component. The directions or positions indicated by the terms "upper", "lower", "left", "right", "front", "back", "vertical", "horizontal", "top", "bottom", "inside", "outside", etc. are based on the directions or positions shown in the accompanying drawings and are only for the convenience of description and cannot be understood as limitations on the present technical solution. The terms "first" and "second" are only used for the convenience of description and cannot be understood as indicating or implying relative importance or implicitly indicating the number of technical features. "Multiple" means two or more, unless otherwise clearly and specifically defined.

[0031] Please see attached Figure 1-8 The purpose of this embodiment is to provide a device for cell ultrasound, including: a base assembly 1, a platform assembly 2 and a column assembly 3; wherein the base body 11 of the base assembly 1 is connected to the column body 31 in the column assembly 3, and the slide groove 32 of the column body 31 is connected to the platform plate 21 of the platform assembly 2.

[0032] It should be noted that the device also includes a perforated plate 4, and a plurality of cell containers 42 are provided on the plate body 41 of the perforated plate 4, and the cell containers 42 contain cell tissues. The device also includes an ultrasonic instrument 5, and the ultrasonic instrument 5 leads to an ultrasonic probe 51 through a connecting line. In this embodiment, a pair of card slots 52 are provided on the ultrasonic probe 51. The device also includes a lampshade assembly 6, and a first avoidance groove 62 and a second avoidance groove 63 are provided on the lampshade body 61 of the lampshade assembly 6. When in use, the first avoidance groove 62 is used for the connecting line of the ultrasonic instrument to pass through, and the second avoidance groove 63 is used to avoid the base body 11 and the platform assembly 2.

[0033] In this embodiment, a groove 12 is provided on the base body 11, and a chuck 17 is provided in the groove 12; a through hole 22 is provided on the platform plate 21, and the through hole 22 is located in the center of the platform plate 21, and the through hole 22 is used for ultrasonic waves to pass through. The ultrasonic probe 51 is directly clamped on the chuck 17 or clamped on the chuck 17 through a pair of clamping grooves 52 thereon. In this embodiment, the diameter of the cell container 42 is smaller than the diameter of the through hole 22, and the diameter of the through hole 22 is equal to the diameter of the ultrasonic probe 51. The central axis of the through hole 22 coincides with the central axis of the fixed ultrasonic probe 51, ensuring that the ultrasonic waves emitted by the ultrasonic probe 51 can all pass through the through hole 22 to irradiate the cell container 42.

[0034] In addition, the base body 11 is provided with a first ultraviolet lamp 13 and a second ultraviolet lamp 14, which are respectively located on both sides of the groove 12. A plug interface 15 and a switch 16 are provided on one side of the base body 11, the plug interface 15 is used to connect a power source or charge, and the switch 16 is used to switch the two ultraviolet lamps, and the two ultraviolet lamps can also be turned on remotely.

[0035] Finally, the platform plate 21 is fixedly connected to the sliding bottom plate 24, one side of the sliding bottom plate 24 is the sliding side plate 25, and the two ends of the sliding bottom plate 24 are the sliding bottom plate 24 and the sliding top plate 23. The column body 31 is provided with a knob 33 that penetrates into the slide groove 32. The sliding bottom plate 24 moves up and down along the slide groove 32, and after the platform plate 21 is adjusted to the required height, the knob 33 is rotated to press against the sliding side plate 25, so as to realize the positioning and height adjustment of the platform plate 21.

[0036] When in use, first put the ultrasonic probe 51 into the groove 12 and fix it, keep the platform plate 21 and the base body 11 at a small distance, then place the lampshade body 61 on the base body 11, cover the base body 11, the ultrasonic probe 51 and the platform plate 21, and then turn on the two ultraviolet lamps for sterilization. After the sterilization is completed, remove the lampshade body 61, place the well plate 4 containing the cell tissue on the platform plate 21, and then adjust the height of the platform plate 21 so that the cell container 42 containing the cell tissue on the well plate 4 contacts the ultrasonic probe 51, turn on the ultrasonic probe 51 to start working, and perform ultrasound on the cell tissue in the cell container 42.

[0037] Any modifications, equivalent substitutions and improvements made within the spirit and principles of this utility model should be included in the protection scope of this utility model.

Claims

1. A device for cell ultrasound, comprising: A base assembly (1), a platform assembly (2) and a column assembly (3); wherein a base body (11) of the base assembly (1) is connected to a column body (31) in the column assembly (3), and a slide groove (32) of the column body (31) is connected to a platform plate (21) of the platform assembly (2); The invention is characterized in that a groove (12) is provided on the base body (11), and a clamp (17) is provided in the groove (12); a through hole (22) is provided on the platform plate (21), and the through hole (22) is located at the center of the platform plate (21); The device also includes a hole plate (4), a plate body (41) of which is provided with a plurality of cell containers (42), wherein the diameter of the cell containers (42) is smaller than the diameter of the through hole (22); the device also includes an ultrasonic instrument (5), wherein the ultrasonic instrument (5) leads to an ultrasonic probe (51) via a connecting line.

2. The device for cell ultrasound according to claim 1, characterized in that A first ultraviolet lamp (13) and a second ultraviolet lamp (14) are arranged on the base body (11); the first ultraviolet lamp (13) and the second ultraviolet lamp (14) are respectively located on two sides of the groove (12).

3. The device for cell ultrasound according to claim 1, characterized in that A plug interface (15) and a switch (16) are provided on one side of the base body (11).

4. The device for cell ultrasound according to claim 1, characterized in that The platform plate (21) is fixedly connected to the sliding bottom plate (24), one side of the sliding bottom plate (24) is a sliding side plate (25), and the two ends of the sliding bottom plate (24) are the sliding bottom plate (24) and the sliding top plate (23).

5. The device for cell ultrasound according to claim 4, characterized in that: The column body (31) is provided with a knob (33) which penetrates into the slide groove (32).

6. The device for cell ultrasound according to claim 1, characterized in that: The ultrasonic probe (51) is provided with a pair of slots (52).

7. The device for cell ultrasound according to claim 1, characterized in that: The device further comprises a lampshade assembly (6), wherein a lampshade body (61) of the lampshade assembly (6) is provided with a first avoidance groove (62) and a second avoidance groove (63).

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