Cervical cancer susceptibility gene noninvasive detection kit

By integrating semiconductor refrigeration sheets, heat absorbing plates and arc-shaped heat absorbing sheets in the cervical cancer susceptibility gene detection kit, the problem of reagent failure during low-temperature storage and transportation is solved, and the effective low-temperature storage and transportation of reagents are achieved.

CN222728671UActive Publication Date: 2025-04-08SHANXI MEDICAL UNIV
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Patent Information

Application Number
CN202421503870.6
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-06-28
Publication Date
2025-04-08
Estimated Expiration
2034-06-28

AI Technical Summary

Technical Problem

The existing cervical cancer susceptibility gene detection kits cannot effectively maintain the low temperature state of the reagent during low temperature storage and transportation, resulting in the problem of reagent failure.

Method used

A non-invasive detection kit for cervical cancer susceptibility genes including semiconductor refrigeration sheets, heat absorbing plates and arc-shaped heat absorbing sheets is designed. Through the combination of semiconductor refrigeration sheets and heat absorbing plates, uninterrupted heat absorbing refrigeration of the reagents is achieved, and the refrigeration and refrigeration effect is achieved.

Benefits of technology

It effectively prevents the failure of the detection reagent during transportation, ensures the stability and effectiveness of the reagent, and can maintain a low temperature state for a long time even without power supply.

✦ Generated by Eureka AI based on patent content.

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  • Figure CN222728671U_ABST
    Figure CN222728671U_ABST
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Abstract

A cervical cancer susceptibility gene noninvasive detection kit comprises a kit body with an opening in the upper portion and a kit cover buckled on the opening in the top of the kit body, a plurality of reagent grooves with upward openings are formed in the kit body, the kit cover is hollow, air holes are formed in the side wall of the top of the kit cover, a semiconductor chilling plate is arranged in the kit cover, and the semiconductor chilling plate is connected with the reagent grooves. The refrigerating surface of the lower surface of the semiconductor refrigerating sheet is in close contact with the heat absorbing plate, a plurality of arc-shaped heat absorbing sheets inserted into the corresponding reagent grooves are fixed on the lower surface of the heat absorbing plate, and one side of the box cover is provided with a power interface for supplying power to the semiconductor refrigerating sheet. When the reagent box is used, the arc-shaped heat absorption sheets can be correspondingly inserted into the reagent grooves, so that the reagents in the reagent grooves are subjected to uninterrupted heat absorption and refrigeration, the refrigeration and cold storage effects are achieved, the interior of the box body can be kept in a low-temperature state for a long time even if power is not supplied in the transportation process, and the failure of the detection reagents can be effectively prevented.
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Description

Technical Field

[0001] The utility model relates to a test kit, in particular to a non-invasive test kit for cervical cancer susceptibility genes. Background Art

[0002] As one of the most common malignant tumors in women worldwide, early detection and prevention of cervical cancer are crucial to improving the survival rate and quality of life of patients. In recent years, with the rapid development of biotechnology, cervical cancer susceptibility gene detection reagents have gradually been widely used in clinical practice, providing new means for the prevention, diagnosis and treatment of cervical cancer. Cervical cancer susceptibility gene detection reagents can assess an individual's risk of cervical cancer by detecting gene mutations or polymorphisms associated with cervical cancer. This assessment result helps patients and doctors better understand the individual's genetic background and develop a personalized health management plan. After assessing the risk of disease, cervical cancer susceptibility gene detection reagents can provide patients with targeted prevention strategies. For example, for high-risk groups, more frequent screening, HPV vaccination and other measures can be taken to reduce the risk of disease. Cervical cancer susceptibility gene detection reagents can quickly and accurately identify individuals with genetic susceptibility. These susceptible populations usually need to be monitored and managed more closely to ensure early detection and treatment of cervical cancer. Therefore, with the continuous advancement of technology and in-depth research, cervical cancer susceptibility gene detection reagents will play an increasingly important role in the prevention, diagnosis and treatment of cervical cancer.

[0003] The storage temperature of the cervical cancer susceptibility gene detection reagent is low, and long-term placement outside the environment can easily cause the reagent to become ineffective. The utility model patent CN218663040U discloses a methylation detection kit for cervical cancer that can be quickly selected, including a kit body and a cover, the top of the kit body is fixedly connected to the cover by a hinge, the inner left and right ends of the kit body are fixedly connected to connecting rods, the outer sides of the connecting rods at the left and right ends are slidably connected to moving blocks, the moving blocks are slidably connected to the kit body, the outer side of the connecting rod is covered with a first spring, and a fixed frame is fixedly connected between the moving blocks at the left and right ends, the inner side of the fixed frame is provided with a reagent bottle, the outer side of the front end of the reagent bottle is fixedly connected to a label plate, and the front end of the fixed frame is fixedly connected to a transparent visual window from left to right in sequence, when the reagent bottle needs to be taken out, the kit body is convenient for selecting the required reagent bottle, and there is no need to take out all the reagent bottles for selection one by one, thereby improving the speed of selecting the reagent bottle. However, the test kit does not have a refrigeration effect and cannot effectively store the reagents in the transport state at low temperatures. Utility Model Content

[0004] In order to solve the above problems, the purpose of the utility model is to provide a non-invasive detection kit for cervical cancer susceptibility genes.

[0005] In order to achieve the above-mentioned purpose, the utility model provides a non-invasive detection kit for cervical cancer susceptibility genes, comprising a box body with an opening on the top and a box cover buckled on the top opening of the box body, a plurality of reagent slots with openings facing upwards are arranged in the box body, the box cover is hollow and a ventilation hole is arranged on the top side wall, a semiconductor cooling sheet is arranged inside the box cover, a cooling surface of the lower surface of the semiconductor cooling sheet is in close contact with a heat absorbing plate, a plurality of arc-shaped heat absorbing sheets inserted into corresponding reagent slots are fixed on the lower surface of the heat absorbing plate, and a power interface for supplying power to the semiconductor cooling sheet is arranged on one side of the box cover.

[0006] Furthermore, a heat dissipation fan is arranged above the semiconductor refrigeration sheet, and the semiconductor refrigeration sheet is embedded in the heat insulation board of the box cover. The heat insulation board divides the box cover into two upper and lower cavities. A heat sink is arranged on the upper surface of the heat insulation board. The heat sink is in close contact with the heating surface of the semiconductor refrigeration sheet. Heat dissipation holes are arranged on the front and rear side walls of the box cover, and the heat dissipation fan discharges the wind blowing the heat sink through the heat dissipation holes.

[0007] Furthermore, both sides of the box cover are movably connected to the box body through lock buckles.

[0008] Furthermore, the box body includes an outer layer and an inner layer, and the inner layer is made of a thermal insulation foam material, and the reagent slots are evenly arranged on the surface of the thermal insulation foam material.

[0009] Furthermore, the ventilation holes and the heat dissipation holes are respectively covered with filter nets.

[0010] Furthermore, the side walls around the heat dissipation fan are fixedly connected to the inner wall of the box body through heat-insulating sponge gaskets.

[0011] Furthermore, a plurality of rubber gaskets are arranged at the bottom of the box body.

[0012] When the utility model is used, the arc-shaped heat-absorbing sheet can be correspondingly inserted into the reagent tank, so as to continuously absorb heat and cool the reagent in the reagent tank, achieving a refrigeration effect. Even if there is no power supply during transportation, the inside of the box body can be kept in a low temperature state for a long time, which can effectively prevent the detection reagent from becoming ineffective. BRIEF DESCRIPTION OF THE DRAWINGS

[0013] Figure 1 It is a three-dimensional structural schematic diagram of the utility model;

[0014] Figure 2 It is a three-dimensional structural schematic diagram of the box cover of the utility model;

[0015] Figure 3 It is a schematic diagram of the side cross-sectional structure of the box cover of the utility model;

[0016] Figure 4 It is a three-dimensional structural schematic diagram of the box body of the utility model. DETAILED DESCRIPTION

[0017] like Figure 1-4 As shown, a non-invasive detection kit for cervical cancer susceptibility genes comprises a box body 1 with an opening on the top and a box cover 2 buckled on the top opening of the box body 1, and both sides of the box cover 2 are movably connected to the box body 1 by locks 12, which are convenient to open and lock. A plurality of reagent slots 3 with openings facing upward are arranged in the box body 1, the box cover 2 is hollow, and a vent 4 is arranged on the top side wall, a semiconductor refrigeration sheet 5 is arranged inside the box cover 2, and a cooling surface of the lower surface of the semiconductor refrigeration sheet 5 is in close contact with a heat absorbing plate 10, and a plurality of arc-shaped heat absorbing sheets 11 inserted into the corresponding reagent slots 3 are fixed on the lower surface of the heat absorbing plate 10, and a power interface for supplying power to the semiconductor refrigeration sheet 5 is arranged on one side of the box cover 2. In order to ensure the heat insulation effect of the box body 1, the box body 1 comprises an outer layer and an inner layer, and the inner layer is made of a heat-insulating foam material, and the reagent slots 3 are evenly arranged on the surface of the heat-insulating foam material, and the arc-shaped heat-absorbing sheet 11 can be correspondingly inserted into the reagent slots 3, thereby continuously absorbing heat and cooling the reagents in the reagent slots 3, thereby achieving a refrigeration and refrigeration effect.

[0018] In order to further make the heating surface of the semiconductor refrigeration plate 5 have a good heat dissipation effect, thereby improving the cooling effect of the cooling surface, a heat dissipation fan 6 is arranged above the semiconductor refrigeration plate 5, and the semiconductor refrigeration plate 5 is embedded in the heat insulation plate 7 of the box cover 2. The heat insulation plate 7 divides the box cover 2 into two upper and lower cavities, and a heat sink 8 is arranged on the upper surface of the heat insulation plate 7. The heat sink 8 is in close contact with the heating surface of the semiconductor refrigeration plate 5. The front and rear side walls of the box cover 2 are provided with heat dissipation holes 9, and the heat dissipation fan 6 allows the wind blowing the heat sink 8 to be discharged through the heat dissipation holes 9, so that the heat of the heating surface of the semiconductor refrigeration plate 5 is dissipated to the heat sink 8, and then finally dissipated to the outside. Since the heating surface and the cooling surface of the semiconductor refrigeration plate 5 are separated by the heat insulation plate 7, the heat of the heating surface can be better dissipated to the outside without affecting the cooling surface.

[0019] The ventilation holes 4 and the heat dissipation holes 9 are respectively covered with filter screens. The surrounding side walls of the heat dissipation fan 6 are fixedly connected to the inner wall of the box body 1 through heat-insulating sponge gaskets 13. A plurality of rubber gaskets 14 are arranged at the bottom of the box body 1.

[0020] Of course, the above description is not a limitation of the present invention, and the present invention is not limited to the above examples. Any changes, modifications, additions or substitutions made by ordinary technicians in this technical field within the essential scope of the present invention should fall within the protection scope of the present invention.

Claims

1. A non-invasive detection kit for cervical cancer susceptibility genes, comprising a box body (1) with an opening at the top and a box cover (2) buckled on the top opening of the box body (1), characterized in that: A plurality of reagent slots (3) with openings facing upward are arranged in the box body (1); the box cover (2) is hollow and has a ventilation hole (4) on the top side wall; a semiconductor cooling sheet (5) is arranged inside the box cover (2); a cooling surface of the lower surface of the semiconductor cooling sheet (5) is in close contact with a heat absorbing plate (10); a plurality of arc-shaped heat absorbing sheets (11) inserted into corresponding reagent slots (3) are fixed on the lower surface of the heat absorbing plate (10); and a power supply interface for supplying power to the semiconductor cooling sheet (5) is arranged on one side of the box cover (2).

2. A non-invasive detection kit for cervical cancer susceptibility genes according to claim 1, characterized in that: A heat dissipation fan (6) is arranged above the semiconductor refrigeration sheet (5), the semiconductor refrigeration sheet (5) is embedded in a heat insulation board (7) of the box cover (2), the heat insulation board (7) divides the box cover (2) into two upper and lower cavities, a heat dissipation sheet (8) is arranged on the upper surface of the heat insulation board (7), the heat dissipation sheet (8) is in close contact with the heating surface of the semiconductor refrigeration sheet (5), the front and rear side walls of the box cover (2) of the heat dissipation sheet (8) are provided with heat dissipation holes (9), and the heat dissipation fan (6) allows the wind blowing the heat dissipation sheet (8) to be discharged through the heat dissipation holes (9).

3. A non-invasive detection kit for cervical cancer susceptibility genes according to claim 1, characterized in that: Both sides of the box cover (2) are movably connected to the box body (1) via lock buckles (12).

4. A non-invasive detection kit for cervical cancer susceptibility genes according to claim 1, characterized in that: The box body (1) comprises an outer layer and an inner layer, and the inner layer is made of a thermal insulation foam material, and the reagent grooves (3) are evenly arranged on the surface of the thermal insulation foam material.

5. A non-invasive detection kit for cervical cancer susceptibility genes according to claim 1, characterized in that: The ventilation holes (4) and the heat dissipation holes (9) are respectively covered with filter screens.

6. A non-invasive detection kit for cervical cancer susceptibility genes according to claim 1, characterized in that: The side walls around the heat dissipation fan (6) are fixedly connected to the inner wall of the box body (1) via heat-insulating sponge gaskets (13).

7. A non-invasive detection kit for cervical cancer susceptibility genes according to claim 1, characterized in that: A plurality of rubber gaskets (14) are arranged at the bottom of the box body (1).

Citation Information

Patent Citations

  • Quickly-selectable detection kit for methylation in cervical cancer

    CN218663040U