A portable sample dispensing system with linkage cleaning function

Abstract

The utility model provides a portable test body dispensing system with a linkage cleaning function, including a test body dispensing device and a control system. The shell frame in the test body dispensing device includes an outer shell, a fixed shell 1, a fixed shell 2, a connecting top plate and a bearing bottom plate. The movable door part includes a movable door, a push rod motor 1 and a limit hook. The linkage fixed part includes a movable push plate, a limit slide column, a "J"-shaped connecting rod, a fixed support plate and a reset spring. The cleaning part includes a liquid injection nozzle, a two-way valve, a screw stepper motor and a pressure rod. The reagent dispensing component unloading part includes an "L"-shaped unloading plate and a push rod motor 2. The process used is to quantitatively dispense various reagent solutions required for the reaction into each microfluidic chip card, thereby greatly reducing the size of the device, significantly reducing the occupied space, and having low energy consumption. It can be adapted to a variety of small and medium-sized in vitro detection work; after the reagent box is used up, the air pump is started to discharge the residual waste liquid in the dispensing module and air-dry the channel.

Description

Technical Field

[0001] The utility model relates to the field of test body dispensing, in particular to a portable test body dispensing system with a linkage cleaning function. Background Art

[0002] Sample dispensing is the process of sucking the sample in the main sample container into the nozzle head and then dispensing it into the sub-sample container in order to subdivide the sample such as blood or urine into the amount required for analysis and examination.

[0003] For example, Chinese patent CN106170704A discloses a sample dispensing device, which includes a main conveying line for conveying a main rack containing sample to be dispensed; a dispensing station arranged along the main conveying line and dispensing the sample from a rack on one side to a rack on the other side; and a sub-rack supply device for supplying a sub-rack holding a container for receiving the sample to be dispensed to the above-mentioned dispensing station. The above-mentioned sample dispensing device is characterized in that at the above-mentioned dispensing station, the processed main rack and sub-rack are transferred together to the above-mentioned main conveying line and conveyed, and a waiting area is set at the above-mentioned dispensing station for allowing the processed main rack and sub-rack to wait before being transferred to the above-mentioned main conveying line, and a main rack passage for positioning the main rack introduced from the above-mentioned main conveying line and a sub-rack passage for positioning the sub-rack transferred from the above-mentioned sub-rack supply device are simultaneously set at the above-mentioned dispensing station, and the main rack that has passed through the above-mentioned main rack passage and the sub-rack that has passed through the above-mentioned sub-rack passage are arranged in the above-mentioned waiting area.

[0004] Similar to the above-mentioned sample dispensing device, there are the following defects in use:

[0005] First, because the existing dispensing device is used to dispense the collected patient samples, a disposable consumable TIP head is required to avoid contamination, which results in high consumables consumption.

[0006] Secondly, it takes up a lot of space, has poor portability, and is only suitable for large-scale in vitro testing. There is serious waste of resources in small and medium-scale in vitro testing.

[0007] Third, when the dispensing station is in use, solutions are added. Some solutions contain salt ions. After long-term use / stationary state, crystals may precipitate in the pipeline and clog the pipeline, making the dispensing station difficult to clean. Utility Model Content

[0008] The utility model provides a portable test body dispensing system with a linkage cleaning function, which can effectively solve the problems mentioned in the background technology.

[0009] In order to achieve the above purpose, the utility model adopts the following technical solutions:

[0010] A portable test body dispensing system with a linkage cleaning function comprises a test body dispensing device and a control system.

[0011] Specifically, the test body dispensing device includes a shell frame, a movable chamber door part, a linkage fixing part, a cleaning part, a reagent dispensing component unloading part and a reagent dispensing component part.

[0012] More specifically, the housing frame includes an outer shell, a fixed shell 1, a fixed shell 2, a connecting top plate and a bearing bottom plate. A rectangular box entry hole is provided on the outer shell; the fixed shell 1 is provided on the inner side surface of the outer shell in a "9" shape; the fixed shell 2 is provided on the right side surface of the fixed shell 1 through the connecting top plate; the two sides of the connecting top plate are respectively connected to the fixed shell 1 and the fixed shell 2; the two sides of the bearing bottom plate are respectively connected to the fixed shell 1 and the fixed shell 2; the connecting top plate is provided with a mounting through hole 1 and a mounting through hole 2; and the bearing bottom plate is provided with a circular pin hole.

[0013] More specifically, the movable door part includes the movable door, a push rod motor 1 and a limit hook. The pin shaft at the lower end of the movable door is connected to the rectangular box entry hole; a fixed hook is arranged on the movable door; the push rod motor 1 is arranged on the inner side of the shell through a "T"-shaped plate, and a strip through hole 1 is arranged on it; the limit hook pin shaft is connected to the strip through hole 1, and its tail end is arranged on the movable end of the push rod motor 1, and the push rod motor 1 is used to drive the hook end of the limit hook to move back and forth, thereby realizing the opening and closing of the movable door.

[0014] More specifically, the linkage fixed part includes a movable push plate 1, a movable push plate 2, a limit slide column 1, a limit slide column 2, a "J"-shaped connecting rod, a fixed support plate and a return spring. A limit slide column 1 is provided on both the fixed shell 1 and the fixed shell 2. A limit slide column 2 is provided on both the fixed shell 1 and the fixed shell 2. The "J"-shaped connecting rod is symmetrically pin-connected to the fixed shell 1 and the fixed shell 2; the limit slide column 1 and the limit slide column 2 are perpendicular to each other; the movable push plate 1 is slidably connected to the limit slide column 1 through a "U"-shaped slider; the movable push plate 2 is slidably connected to the limit slide column 2 through a "U"-shaped slider; the upper end pin of the "J"-shaped connecting rod is connected to the movable push plate 2, and the lower end pin is connected to the movable push plate 1; one end of the return spring is provided on the movable push plate 1, and the other end is provided on the outer shell.

[0015] More specifically, the cleaning part includes a liquid injection nozzle, a vacuum pump, a two-way valve, a screw stepper motor and a pressure rod. The liquid injection nozzle is arranged in the installation through hole 1, and the liquid injection nozzle is connected to the two-way valve; the two-way valve is connected to the vacuum pump; the screw stepper motor is arranged on the side of the fixed shell 2, and a movable pressure plate is arranged at its movable end; the movable pressure plate is slidably connected to the side of the fixed shell 2 through a "U"-shaped slider 3 and a strip slide rail 3; the pressure rod is arranged on the movable pressure plate, and is used to push the piston of the reagent dispensing component part.

[0016] More specifically, the reagent dispensing assembly unloading part includes an "L"-shaped unloading plate and a push rod motor 2. The "L"-shaped unloading plate is arranged on the movable push plate 2 to adjust the position of the reagent dispensing assembly; the push rod motor 2 is arranged on the movable pressure plate through the "L"-shaped connecting plate.

[0017] More specifically, the reagent dispensing component comprises a connecting base plate, a reagent tube and a piston. The connecting base plate is provided with three equidistant circular pin holes; the reagent tube is equidistantly arranged in the three circular pin holes, and a liquid injection through hole is arranged at the bottom end thereof; and the piston is slidably connected in the reagent tube.

[0018] Specifically, the control system includes a control mechanism, a feedback mechanism and a PLC controller. The control mechanism includes a start switch, a take-out switch and a pause switch. The feedback mechanism includes a distance sensor module.

[0019] Furthermore, an "n"-shaped limiting plate is added to the outer shell.

[0020] Furthermore, a "C"-shaped limit block is added to the movable end of the push rod motor 2.

[0021] Furthermore, an annular sealing strip is added to the movable warehouse door.

[0022] Advantages compared to the prior art:

[0023] In the utility model, the following functions are realized by integrating the housing frame, the movable door part, the linkage fixing part, the cleaning part, the reagent dispensing component unloading part and the reagent dispensing component part with the control system:

[0024] Firstly, compared with the dispensing device in the background technology, the utility model adopts a process of quantitatively dispensing various reagent solutions (non-patient samples) required for the reaction into each microfluidic chip card. The size of the device is greatly reduced, the occupied space is significantly reduced, the energy consumption is low, and the portability is also improved.

[0025] Secondly, the configuration of the shell frame, the movable door part, and the reagent dispensing component unloading part in the utility model significantly improves the adaptability, and can be adapted to a variety of in vitro detection equipment, intelligent laboratory equipment, and automation equipment.

[0026] Thirdly, in view of the pipe blockage problem of the dispensing station in the prior art, the cleaning part of the utility model can start the air pump after the reagent box is used up to discharge the residual waste liquid in the "dispensing module in the test body dispensing device" and air dry the channel, linking the cleaning function, significantly reducing the cleaning difficulty of the test body dispensing device, avoiding crystallization in the pipeline, and greatly improving the service life. The dispensing module includes a liquid injection nozzle, a two-way valve, and a conduit from the reagent dispensing component to the "microfluidic chip card". BRIEF DESCRIPTION OF THE DRAWINGS

[0027] Figure 1 The three-dimensional structure of the utility model is shown in FIG. Figure 1 ;

[0028] Figure 2 The three-dimensional structure of the utility model is shown in FIG. Figure 2 ;

[0029] Figure 3 This is a schematic diagram of the top view structure of the utility model;

[0030] Figure 4 This is a side view of the structure of the utility model;

[0031] Figure 5 The utility model is a schematic diagram of a partial cross-sectional structure from the side Figure 1 ;

[0032] Figure 6 The utility model is a schematic diagram of a partial cross-sectional structure from the side Figure 2 ;

[0033] Figure 7 This is a schematic diagram of the system structure of the utility model.

[0034] In the figure: 101. housing, 102. fixed housing 1, 103. fixed housing 2, 104. connecting top plate, 105. bearing bottom plate, 201. movable compartment door, 202. push rod motor 1, 203. limit hook, 301. movable push plate 1, 302. movable push plate 2, 303. limit slide column 1, 304. limit slide column 2, 305. "J"-shaped connecting rod, 306. reset spring, 401. injection nozzle, 402. two-way valve, 403. screw stepper motor, 404. pressure rod, 501. "L"-shaped unloading plate, 502. push rod motor 2, 601. connecting bottom plate, 602. reagent tube. DETAILED DESCRIPTION

[0035] Example 1, refer to the attached Figure 1-7 , a portable sample dispensing system with a linkage cleaning function, comprising a sample dispensing device and a control system.

[0036] The test body dispensing device comprises a shell frame, a movable compartment door part, a linkage fixing part, a cleaning part, a reagent dispensing component unloading part and a reagent dispensing component part.

[0037] The housing frame includes an outer shell 101 , a fixing shell 1 102 , a fixing shell 2 103 , a connecting top plate 104 and a bearing bottom plate 105 .

[0038] The housing 101 is provided with a rectangular box entry hole.

[0039] The fixing shell 102 is disposed on the inner side of the outer shell 101 and is in a "9" shape.

[0040] The second fixing shell 103 is disposed on the right side surface of the first fixing shell 102 by connecting the top plate 104 .

[0041] The two sides of the connecting top plate 104 are respectively connected to the fixing shell 1 102 and the fixing shell 2 103. The two sides of the bearing bottom plate 105 are respectively connected to the fixing shell 1 102 and the fixing shell 2 103.

[0042] The connecting top plate 104 is provided with a first mounting through hole and a second mounting through hole.

[0043] A circular pin hole is disposed on the supporting base plate 105 .

[0044] The movable door part includes a movable door 201, a push rod motor 202 and a limit hook 203.

[0045] The pin shaft at the lower end of the movable door 201 is connected to the rectangular box entry hole; a fixing hook is arranged on the movable door 201.

[0046] The push rod motor 202 is arranged on the inner side surface of the housing 101 through a "T"-shaped plate.

[0047] A strip through hole is arranged on the "T"-shaped plate.

[0048] The limiting hook 203 is pin-connected to the first strip-shaped through hole.

[0049] The tail end of the limit hook 203 is arranged on the movable end of the push rod motor 1 202 .

[0050] The push rod motor 1 is used to drive the hook end of the limit hook 203 to move back and forth, thereby realizing the opening and closing of the movable warehouse door 201.

[0051] The linkage fixed part includes a movable push plate 1 301 , a movable push plate 2 302 , a limit slide column 1 303 , a limit slide column 2 304 , a “J”-shaped connecting rod 305 , a fixed support plate and a return spring 306 .

[0052] The fixed housing 1 102 and the fixed housing 2 103 are both provided with a limit sliding post 1 303 .

[0053] The first fixing housing 102 and the second fixing housing 103 are both provided with a second limiting sliding post 304 .

[0054] The “J”-shaped connecting rod 305 is symmetrically pin-connected to the fixed housing 102 and the fixed housing 2 103 .

[0055] The first limiting sliding post 303 and the second limiting sliding post 304 are perpendicular to each other.

[0056] The movable push plate 301 is slidably connected to the limiting slide column 303 through a "U"-shaped slider.

[0057] The movable push plate 2 302 is slidably connected to the limiting slide post 2 304 via a U-shaped slider.

[0058] The upper end pin of the “J”-shaped connecting rod 305 is connected to the movable push plate 2 302 .

[0059] The lower end pin of the “J” shaped connecting rod 305 is connected to the movable push plate 1 301 .

[0060] One end of the return spring 306 is disposed on the movable push plate 1 301 , and the other end is disposed on the housing 101 .

[0061] The cleaning part includes a liquid injection nozzle 401 , a vacuum pump, a two-way valve 402 , a screw stepping motor 403 and a pressure rod 404 .

[0062] The liquid injection nozzle 401 is disposed in the first installation through hole, and the liquid injection nozzle 401 is connected to the two-way valve 402 .

[0063] Two two-way valves 402 are provided, and a port between the two-way valves 402 is connected through a conduit to form a "K"-shaped channel; a port of the two-way valve 402 is connected to the vacuum pump.

[0064] The screw stepper motor 403 is disposed on the side surface of the second fixed housing 103 .

[0065] A movable pressing plate is arranged at the movable end of the screw stepping motor 403 .

[0066] The movable pressing plate is slidably connected to the side surface of the fixed shell 2 103 through a U-shaped sliding block 3 and a strip sliding rail 3.

[0067] The pressure rod 404 is disposed on the movable pressure plate and is used to push the piston of the reagent dispensing component.

[0068] The unloading part of the reagent dispensing assembly includes an “L”-shaped unloading plate 501 and a push rod motor 502 .

[0069] The "L"-shaped unloading plate 501 is disposed on the movable push plate 2 302 and is used to adjust the position of the reagent dispensing assembly.

[0070] The push rod motor 2 502 is arranged on the movable pressure plate through an "L"-shaped connecting plate.

[0071] The reagent dispensing assembly includes a connecting base plate 601, a reagent tube 602 and a piston.

[0072] Three circular pin holes are equidistantly arranged on the connecting bottom plate 601 .

[0073] The reagent tubes 602 are equidistantly arranged in the circular pin hole three.

[0074] A liquid injection through hole is provided at the bottom end of the reagent tube 602.

[0075] The piston is slidably connected to the reagent tube 602.

[0076] The control system includes a control mechanism, a feedback mechanism and a PLC controller.

[0077] The control mechanism includes a start switch, a take-out switch and a pause switch.

[0078] The start switch and the pause switch are arranged on the side plate of the housing 101 .

[0079] The take-out switch is disposed on the movable door 201 .

[0080] The feedback mechanism includes a distance sensor module.

[0081] The distance sensor module is arranged on the “T”-shaped plate to assist the PLC controller in detecting the position of the movable door 201 .

[0082] Working principle and usage:

[0083] The first step is pre-setting:

[0084] Press the start switch to power on and debug the system. Install the dispensing conduit, one end of which is connected to the liquid injection nozzle 401, and the other end of which is connected to the container to be injected.

[0085] According to the requirements, the liquid outlet of the external "cleaning liquid storage device" is connected to the port of a two-way valve 402 in the sample dispensing device. The liquid inlet of the waste liquid collection device (the end originally used for liquid injection) is connected to the port of one of the two-way valves 402 through a catheter.

[0086] Step 2: Note:

[0087] The reagent dispensing component part is pushed onto the movable push plate 2 302 , and the connecting bottom plate 601 of the reagent dispensing component part is located below the “L”-shaped unloading plate 501 .

[0088] The movable chamber door 201 is closed, and the movable push plate 1 301 moves backward, pushing the "J"-shaped connecting rod 305 to move, and the "J"-shaped connecting rod 305 pushes the movable push plate 2 302, and the movable push plate 2 302 moves upward, so that the reagent dispensing component part moves upward, and the reagent dispensing component part is connected with the injection nozzle 401. The distance sensor module outputs a signal to the PLC controller, and the PLC controller outputs a signal to the screw stepping motor 403.

[0089] The screw stepper motor 403 drives the piston to move upward, and the reaction solution in the reagent dispensing component part (reagent box) is dispensed to 20 (adjustable) "microfluidic chip cards" in equal amounts at intervals or continuously.

[0090] Step 3: Cleaning:

[0091] The PLC controller delays the output signal to the vacuum pump and the two-way valve 402.

[0092] The two-way valve 402 is started to inject the cleaning liquid into the reagent tube 602 of the reagent dispensing component part through the injection nozzle 401.

[0093] Afterwards, the screw stepper motor 403 drives the piston to move upward, so that the cleaning liquid is discharged from the two-way valve 402 to the relevant waste liquid collection equipment.

[0094] Then, the vacuum pump is started to discharge the remaining liquid in the reagent tube 602 of the reagent dispensing component, and at the same time, the residual waste liquid in the dispensing module is discharged and the channel is air-dried.

[0095] Finally, the related screw stepper motor 403 and the two-way valve 402 are reset.

[0096] Step 4: Take out:

[0097] When the removal switch is pressed, the PLC controller outputs a signal to the push rod motor 202, and the push rod motor 202 drives the limit hook 203 to move.

[0098] The movable push plate 1 301 is reset under the action of the reset spring 306, pushing the "J"-shaped connecting rod 305 to move, and the "J"-shaped connecting rod 305 pushes the movable push plate 2 302, and the movable push plate 2 302 moves down and resets, so that the "L"-shaped unloading plate 501 on the reagent dispensing component part moves down, driving the reagent dispensing component part to separate from the injection nozzle 401.

[0099] The PLC controller delays the output signal to the push rod motor 502, and the push rod motor 502 starts to push the reagent tube 602 of the reagent dispensing component part to move outward, making it convenient for the staff to take it out.

[0100] Embodiment 2, based on embodiment 1, adds a "C"-shaped limit block on the movable end of the push rod motor 2 502.

[0101] Embodiment 3, based on embodiment 1, an “n” shaped limiting plate is additionally provided on the housing 101 to facilitate the position adjustment of the movable door 201 .

[0102] Embodiment 4, based on embodiment 1, an annular sealing strip is additionally provided on the movable door 201 .

[0103] The dispensing module of the present invention comprises a liquid tip nozzle 401, a two-way valve 402, and a conduit from a reagent dispensing component part to a "microfluidic chip card".

[0104] The screw stepper motor described in the utility model comprises a servo motor, a ball screw pair, and a nut seat; the servo motor and the ball screw pair are driven by a screw. The ball screw pair comprises a combination of a ball screw, a ball nut, a rotating steel ball, and a circulating part. The nut seat is connected to the ball nut of the ball screw pair.

Claims

1. A portable sample dispensing system with a linkage cleaning function, comprising a sample dispensing device and a control system, wherein the sample dispensing device comprises a housing frame, a movable door portion, a linkage fixing portion, a cleaning portion, a reagent dispensing component unloading portion and a reagent dispensing component portion; the housing frame comprises an outer shell (101), a fixed shell 1 (102), a fixed shell 2 (103), a connecting top plate (104) and a bearing bottom plate (105); the movable door portion comprises a movable door (201), a push rod motor 1 (202) and a limit hook (203); the linkage fixing portion comprises a movable push plate 1 (301), a movable push plate 2 (302), a limit slide column 1 (303), a limit slide column 2 (304), a "J"-shaped connecting rod (305), a fixed support plate and a linkage fixing portion; The cleaning part comprises a liquid injection nozzle (401), a vacuum pump, a two-way valve (402), a screw stepping motor (403) and a pressure rod (404); the liquid injection nozzle (401) is arranged in the installation through hole one, and the liquid injection nozzle (401) is connected to the two-way valve (402); the two-way valve (402) is connected to the vacuum pump; the screw stepping motor (403) is arranged on the side of the fixed shell two (103); a movable pressing plate is arranged on the nut seat of the screw stepping motor (403); the movable pressing plate is slidably connected to the side of the fixed shell two (103) through a "U"-shaped sliding block three and a strip sliding rail three; the pressure rod (404) is arranged on the movable pressing plate; the unloading part of the reagent dispensing component comprises an "L"-shaped unloading plate (501) and a push rod motor two (502).

2. According to claim 1, a portable sample dispensing system with a linkage cleaning function is characterized in that: A rectangular box entry hole is provided on the outer shell (101); a fixed shell 1 (102) is provided on the inner side surface of the outer shell (101); a fixed shell 2 (103) is provided on the right side surface of the fixed shell 1 (102) through a connecting top plate (104); two sides of the connecting top plate (104) are respectively connected to the fixed shell 1 (102) and the fixed shell 2 (103); two sides of the bearing bottom plate (105) are respectively connected to the fixed shell 1 (102) and the fixed shell 2 (103); a mounting through hole 1 and a mounting through hole 2 are provided on the connecting top plate (104); and a circular pin hole is provided on the bearing bottom plate (105).

3. The portable sample dispensing system with linkage cleaning function according to claim 1, characterized in that: The pin shaft at the lower end of the movable door (201) is connected to the rectangular box entry hole; a fixing hook is arranged on the movable door (201); a push rod motor (202) is arranged on the inner side surface of the housing (101) through a "T"-shaped plate; a strip-shaped through hole (1) is arranged on the "T"-shaped plate; a limit hook (203) pin shaft is connected to the strip-shaped through hole (1); and the tail end of the limit hook (203) is arranged on the movable end of the push rod motor (202).

4. The portable sample dispensing system with linkage cleaning function according to claim 1, characterized in that: A limit slide post 1 (303) is disposed on both the fixed shell 1 (102) and the fixed shell 2 (103); a limit slide post 2 (304) is disposed on both the fixed shell 1 (102) and the fixed shell 2 (103); a "J"-shaped connecting rod (305) is pin-connected to the fixed shell 1 (102) and the fixed shell 2 (103); the limit slide post 1 (303) and the limit slide post 2 (304) are perpendicular to each other; the movable push plate 1 (301) is connected to the fixed shell 1 (102) and the fixed shell 2 (103) by a "U The "U"-shaped slider is slidably connected to the limiting slider (303); the movable push plate (302) is slidably connected to the limiting slider (304) via the "U"-shaped slider; the upper end pin of the "J"-shaped connecting rod (305) is connected to the movable push plate (302), and the lower end pin is connected to the movable push plate (301); one end of the return spring (306) is arranged on the movable push plate (301), and the other end is arranged on the housing (101).

5. The portable sample dispensing system with linkage cleaning function according to claim 1, characterized in that: The "L"-shaped unloading plate (501) is arranged on the movable push plate 2 (302); the push rod motor 2 (502) is arranged on the movable pressure plate through the "L"-shaped connecting plate.

6. The portable sample dispensing system with linkage cleaning function according to claim 1, characterized in that: The reagent dispensing component part comprises a connecting base plate (601), a reagent tube (602) and a piston; a circular pin hole three is arranged on the connecting base plate (601); the reagent tube (602) is arranged in the circular pin hole three; a liquid injection through hole is arranged at the bottom end of the reagent tube (602); and the piston is slidably connected in the reagent tube (602).

7. The portable sample dispensing system with linkage cleaning function according to claim 1, characterized in that: A "C" shaped limit block is added to the movable end of the push rod motor 2 (502).

8. The portable sample dispensing system with linkage cleaning function according to claim 1, characterized in that: The fixing shell 1 (102) is in the shape of a "9".

9. The portable sample dispensing system with linkage cleaning function according to claim 1, characterized in that: An "n"-shaped limiting plate is additionally provided on the housing (101).

10. The portable sample dispensing system with linkage cleaning function according to claim 1, characterized in that: An annular sealing strip is added to the movable door (201).

Images