Liquid medicine cooling and uniform mixing device

Abstract

The utility model relates to a liquid medicine cooling and uniform mixing device which comprises a suspension support, a liquid medicine cooling device and a liquid medicine mixing device. The first refrigerating plate is used for reducing the temperature of the liquid medicine in the liquid medicine bag; the second refrigeration plate is arranged opposite to the first refrigeration plate, and the second refrigeration plate and the first refrigeration plate are spaced to form a containing space; the first driving mechanism is used for driving the second refrigeration plate to reciprocate relative to the first refrigeration plate. According to the liquid medicine cooling and uniform mixing device, efficient cooling, uniform mixing and accurate temperature control of bagged liquid medicine are achieved through the efficient refrigeration plate, the reasonable heat dissipation structure and reciprocating motion of the second refrigeration plate driven by the driving mechanism, and automation and integration of the liquid medicine treatment process are guaranteed. The device is simple in structure and convenient to operate, the operation can be automatically completed only by fixing the liquid medicine bag and setting parameters, the defects in the related technology are effectively overcome, and the wide application prospect is achieved.

Description

Technical Field

[0001] The utility model relates to the technical field of liquid medicine processing equipment, in particular to a liquid medicine cooling and mixing device. Background Art

[0002] In the prior art, with the rapid development of biopharmaceuticals, cell therapy and other fields, the demand for the processing of bagged drug solutions is increasing. In these fields, it is usually necessary to cool and mix the bagged drug solutions to ensure the activity, uniformity and safety of the drug solutions.

[0003] Traditional methods for cooling bagged liquid medicine usually use ice baths or refrigerators. These methods have disadvantages such as slow cooling speed, low temperature control accuracy, and cumbersome operation. In addition, the traditional method of mixing liquid medicine is usually to manually shake the liquid medicine bag. This method is not only inefficient, but also easily causes liquid medicine contamination and operator fatigue. Summary of the invention

[0004] In order to solve the above problems, the utility model provides a liquid medicine cooling and mixing device which can achieve efficient cooling, uniform mixing and precise temperature control of bagged liquid medicine.

[0005] In order to achieve the above-mentioned purpose, the liquid medicine cooling and mixing device designed by the utility model comprises:

[0006] A suspension bracket, used to fix the liquid medicine bag;

[0007] The first refrigeration plate is used to reduce the temperature of the medicine liquid in the medicine bag;

[0008] A second refrigeration plate is arranged opposite to the first refrigeration plate, and an accommodating space is formed between the second refrigeration plate and the first refrigeration plate;

[0009] A first driving mechanism, used for driving the second refrigeration plate to reciprocate relative to the first refrigeration plate;

[0010] When the second refrigeration plate reciprocates relative to the first refrigeration plate, the medicine liquid bag placed in the accommodating space is repeatedly pressed toward the first refrigeration plate to achieve cooling and mixing of the medicine liquid.

[0011] To avoid heat build-up from refrigeration, it also includes:

[0012] A first heat-insulating cover is connected to the first refrigeration plate and encloses a first heat-dissipating cavity;

[0013] A second heat-insulating cover is connected to the second refrigeration plate and encloses a second heat-dissipating cavity;

[0014] A first heat dissipation fan is disposed in the first heat dissipation cavity;

[0015] A second heat dissipation fan is disposed in the second heat dissipation cavity;

[0016] A heat dissipation pipe connecting the first heat dissipation cavity and the second heat dissipation cavity;

[0017] The second cooling fan is configured to transport the heat generated by the refrigeration of the second refrigeration plate to the first cooling cavity through the cooling pipe; the first heat insulation cover is provided with a cooling port, which is used to discharge the heat in the first cooling cavity.

[0018] In order to simplify the structural design, a plurality of guide cylinders are arranged in the first heat insulation cover, and the heat dissipation pipe is slidably matched with the guide cylinders; one end of the heat dissipation pipe extends out of the first heat insulation cover and is connected to the second heat insulation cover to connect the first heat dissipation cavity and the second heat dissipation cavity.

[0019] In order to simply and effectively drive the second refrigeration plate, the first driving mechanism is arranged in the first heat insulation cover and connected to all the heat dissipation tubes. The first driving mechanism is used to synchronously drive all the heat dissipation tubes to drive the second refrigeration plate to move horizontally back and forth relative to the first refrigeration plate.

[0020] In order to improve the heat dissipation efficiency and speed up the heat dissipation speed, the heat dissipation port is equipped with an exhaust fan.

[0021] In order to achieve real-time monitoring and precise control of the liquid temperature, it also includes:

[0022] A second driving mechanism is disposed in the first heat insulation cover and is used to provide a driving force;

[0023] The temperature measuring plate is arranged opposite to the first refrigeration plate and is configured to reciprocate relative to the first refrigeration plate under the drive of the second driving mechanism;

[0024] A temperature sensor is arranged on the temperature measuring board;

[0025] When the temperature measuring plate and the first refrigeration plate squeeze the medicine liquid bag, the temperature sensor detects the temperature of the medicine liquid.

[0026] In order to facilitate the weighing operation of the liquid medicine, the suspension support comprises:

[0027] A weighing device, used to weigh the liquid medicine;

[0028] A hook is installed on the weighing device and is used to hang the medicine liquid bag.

[0029] In order to improve the refrigeration efficiency of the refrigeration plate, the first refrigeration plate and the second refrigeration plate are both semiconductor refrigeration plates, on which heat dissipation fins are arranged.

[0030] In order to prevent the operator from accidentally touching the moving part, a protective cover is also included, which is fixedly connected to the first heat insulation cover. The suspension bracket and the second refrigeration plate are both located in the protective cover, and an openable and closable isolation door is provided on the protective cover.

[0031] The liquid medicine cooling and mixing device designed by the utility model realizes efficient cooling, uniform mixing and precise temperature control of bagged liquid medicine through efficient cooling plates, reasonable heat dissipation structure and reciprocating motion of the second cooling plate driven by the driving mechanism, ensuring the automation and integration of the liquid medicine processing process. The device has a simple structure and convenient operation. It only needs to fix the liquid medicine bag and set the parameters to automatically complete the operation, which effectively solves the shortcomings of the relevant technology and has broad application prospects. BRIEF DESCRIPTION OF THE DRAWINGS

[0032] Figure 1 It is a schematic diagram of the three-dimensional structure of the liquid medicine cooling and mixing device provided in an embodiment of the present application;

[0033] Figure 2 It is a schematic diagram of the planar structure of the liquid medicine cooling and mixing device provided in an embodiment of the present application;

[0034] Figure 3 This is a schematic diagram of the first refrigeration plate assembly provided in an embodiment of the present application;

[0035] Figure 4 is a schematic diagram of the accommodating space structure provided in an embodiment of the present application;

[0036] Figure 5 is a schematic diagram of the structure of the protective cover provided in an embodiment of the present application;

[0037] Figure 6 It is a structural schematic diagram of the first heat dissipation cavity connected to the second heat dissipation cavity provided in an embodiment of the present application.

[0038] Among them: a suspension bracket 10, a first refrigeration plate 20, a second refrigeration plate 30, an accommodating space 40, a first driving mechanism 50, a first heat insulation cover 60, a first heat dissipation cavity 61, a second heat insulation cover 70, a second heat dissipation cavity 71, a first cooling fan 62, a second cooling fan 72, a cooling pipe 80, a cooling port 63, a guide tube 81, an exhaust fan 64, a second driving mechanism 90, a temperature measuring plate 91, a temperature sensor 92, a weighing device 11, a hook 12, a cooling fin 21, a liquid medicine bag 100, a protective cover 101, and an isolation door 102. DETAILED DESCRIPTION

[0039] The preferred embodiments of the present invention are described below in conjunction with the accompanying drawings. It should be understood that the preferred embodiments described herein are only used to illustrate and explain the present invention, and are not used to limit the present invention.

[0040] Example 1.

[0041] See also Figures 1 to 6 As shown, the liquid medicine cooling and mixing device described in this embodiment includes:

[0042] A suspension bracket 10, used to fix the liquid medicine bag 100;

[0043] The first refrigeration plate 20 is used to reduce the temperature of the medicine liquid in the medicine liquid bag 100;

[0044] The second refrigeration plate 30 is arranged opposite to the first refrigeration plate 20, and an accommodating space 40 is formed between the second refrigeration plate 30 and the first refrigeration plate 20;

[0045] A first driving mechanism 50, used for driving the second refrigeration plate 30 to reciprocate relative to the first refrigeration plate 20;

[0046] When the second refrigeration plate 30 reciprocates relative to the first refrigeration plate 20 , the liquid medicine bag 100 placed in the accommodating space 40 is repeatedly pressed toward the first refrigeration plate 20 to achieve cooling and mixing of the liquid medicine.

[0047] During operation, illustratively: first, the packaged medicine liquid bag 100 is fixed on the suspension bracket 10 to ensure that the medicine liquid bag 100 is stably placed in the accommodating space 40, and the first driving mechanism 50 (for example, a cylinder driving mechanism) drives the second refrigeration plate 30 to reciprocate at a preset frequency and stroke. During this process, the second refrigeration plate 30 periodically squeezes the medicine liquid bag 100 to make it fully contact with the first refrigeration plate 20, that is, the medicine liquid bag 100 is in full contact with the first refrigeration plate 20 and the second refrigeration plate 30 to quickly take away the heat of the medicine liquid and achieve rapid cooling. At the same time, the reciprocating squeezing motion of the second refrigeration plate 30 prompts convection to form inside the medicine liquid to complete the mixing work.

[0048] In some embodiments, when the second refrigeration plate 30 is driven, the medicine liquid bag 100 periodically contacts the first refrigeration plate 20 with the reciprocating motion of the second refrigeration plate 30. That is, the medicine liquid bag 100 contacts the first refrigeration plate 20 each time the second refrigeration plate 30 is squeezed. This method is suitable for situations where the mixing requirements are not high and the material of the medicine liquid bag 100 is relatively soft.

[0049] In other embodiments, when the second refrigeration plate 30 is driven, the second refrigeration plate 30 moves toward the first refrigeration plate 20 by a predetermined distance so that the medicine liquid bag 100 is always close to the first refrigeration plate 20, so that the medicine liquid bag 100 is repeatedly squeezed by the second refrigeration plate 30 while always in contact with the first refrigeration plate 20. That is, after the second refrigeration plate 30 moves by a predetermined distance, the medicine liquid bag 100 is always pressed against the surface of the first refrigeration plate 20, and then the second refrigeration plate 30 performs a reciprocating motion to squeeze the medicine liquid bag 100. This method is suitable for situations where the mixing requirements are high or the medicine liquid bag 100 is relatively hard, and this method can also increase the cooling speed of the medicine liquid in the medicine liquid bag 100.

[0050] In this way, using the above-mentioned structural design, the operator only needs to fix the medicine liquid bag 100 on the suspension bracket 10, set the refrigeration temperature of the first refrigeration plate 20 and the second refrigeration plate 30, as well as parameters such as the movement frequency and operating time of the first drive mechanism 50, and the cooling and mixing operations can be automatically completed, which greatly simplifies the operation process and improves work efficiency.

[0051] In addition, in this embodiment, the second refrigeration plate 30 is designed to reciprocate in the horizontal direction. On the one hand, the horizontal reciprocating motion can make the extrusion force on the medicine liquid bag 100 more uniform, and at the same time, it can also make the medicine liquid form more sufficient convection and tumbling in the bag to achieve a uniform mixing effect. On the other hand, compared with non-horizontal movement, horizontal movement is easier to achieve through common linear motion mechanisms (such as screws, gear racks, crank connecting rods, etc.), the structural design and installation are simpler, and the cost is easier to control.

[0052] In some embodiments, see Figure 3 , Figure 4 and Figure 6 As shown, it also includes:

[0053] A first heat-insulating cover 60 is connected to the first refrigeration plate 20 and encloses a first heat-dissipating cavity 61;

[0054] The second heat insulation cover 70 is connected to the second refrigeration plate 30 and encloses a second heat dissipation cavity 71;

[0055] A first heat dissipation fan 62 is disposed in the first heat dissipation cavity 61;

[0056] A second heat dissipation fan 72 is disposed in the second heat dissipation cavity 71;

[0057] The heat dissipation pipe 80 is connected with the first heat dissipation cavity 61 and the second heat dissipation cavity 71;

[0058] The second cooling fan 72 is configured to transfer the heat generated by the second cooling plate 30 to the first cooling cavity 61 through the cooling pipe 80 ; the first heat shield 60 is provided with a cooling port 63 for discharging the heat in the first cooling cavity 61 .

[0059] In this embodiment, the first refrigeration plate 20 and the second refrigeration plate 30 are both semiconductor refrigeration plates, on which heat dissipation fins 21 are disposed. Figure 6 As shown, the heat dissipation fins 21 corresponding to the first refrigeration plate 20 and the second refrigeration plate 30 are respectively located in the first heat dissipation cavity 61 and the second heat dissipation cavity 71, and the first heat dissipation fan 62 and the second heat dissipation fan 72 are respectively installed on the corresponding heat dissipation fins to accelerate the heat dissipation of the refrigeration plates.

[0060] The specific working process is as follows: when the device performs a cooling and mixing operation, the heat generated by the second refrigeration plate 30 during the refrigeration process will be blocked by the second heat insulation cover 70 in the second heat dissipation cavity 71, and the second heat dissipation fan 72 draws out the hot air in the cavity and transports it to the first heat dissipation cavity 61 through the heat dissipation pipe 80. At the same time, the heat generated by the first refrigeration plate 20 during operation is also accumulated in the first heat dissipation cavity. Finally, all the hot air is uniformly discharged to the outside of the device by the first heat dissipation fan 62.

[0061] In this embodiment, in order to speed up the heat dissipation, the heat dissipation port 63 is configured with an exhaust fan 64 .

[0062] This centralized discharge design can more conveniently control the heat dissipation direction, for example, directing the heat to a position away from the accommodating space 40 to avoid affecting the cooling efficiency of the medicine bag 100, while effectively preventing heat accumulation from affecting the refrigeration efficiency, thereby ensuring long-term stable operation of the device.

[0063] In some embodiments, see Figure 3 , Figure 4 and Figure 6 As shown, a plurality of guide cylinders 81 are provided in the first heat shield 60, and the heat dissipation pipe 80 is slidably matched with the guide cylinder 81; one end of the heat dissipation pipe 80 extends out of the first heat shield 60 and is connected to the second heat shield 70 to connect the first heat dissipation cavity 61 and the second heat dissipation cavity 71.

[0064] Specifically, a plurality of guide cylinders 81 are arranged on the side wall of the first heat shield 60 close to the second heat shield 70, and are evenly distributed around the heat dissipation tube 80. The guide cylinder 81 is made of wear-resistant material, such as POM, and its inner diameter is slightly larger than the outer diameter of the heat dissipation tube 80, so that the heat dissipation tube 80 can slide freely therein, and the heat dissipation tube 80 passes through the guide cylinder 81 and forms a sliding fit therewith. This design enables the heat dissipation tube 80 to move along with the horizontal reciprocating motion of the second refrigeration plate 30 driven by the first driving mechanism 50, thereby ensuring the stability of the motion. It is worth mentioning that this design allows the heat dissipation tube 80 to have the function of a guide rod, avoiding the need for an additional guide rod, making the overall structure more streamlined and compact, while also reducing the manufacturing cost and assembly difficulty.

[0065] In this embodiment, four heat dissipation pipes 80 are provided, and the four heat dissipation pipes 80 are respectively connected to four corners of the second heat insulation cover 70 to improve the stability of the movement of the second heat insulation cover 70 .

[0066] In some embodiments, see Figure 3 , Figure 4 and Figure 6As shown, the first driving mechanism 50 is disposed in the first heat insulation cover 60 and connected to all the heat dissipation tubes 80 . The first driving mechanism 50 is used to synchronously drive all the heat dissipation tubes 80 to drive the second refrigeration plate 30 to move horizontally back and forth relative to the first refrigeration plate 20 .

[0067] In a specific implementation, illustratively: the first drive mechanism 50 (for example, a servo motor + lead screw structure may be adopted) is fixedly mounted on the side inside the first heat insulation cover 60, and the output end of the first drive mechanism 50 (for example, the nut seat of the lead screw) is fixedly connected to all the heat dissipation tubes 80 through a synchronization plate, so that when the first drive mechanism 50 is working, its output end drives all the heat dissipation tubes 80 to synchronously perform horizontal reciprocating motion.

[0068] In some embodiments, see Figure 1 and Figure 2 As shown, it also includes:

[0069] A second driving mechanism 90 is disposed in the first heat shield 60 and is used to provide a driving force;

[0070] The temperature measuring plate 91 is disposed opposite to the first refrigeration plate 20 and is configured to reciprocate relative to the first refrigeration plate 20 under the drive of the second driving mechanism 90;

[0071] A temperature sensor 92 is provided on the temperature measuring plate 91;

[0072] When the temperature measuring plate 91 and the first refrigeration plate 20 squeeze the medicine liquid bag 100 , the temperature sensor 92 detects the temperature of the medicine liquid.

[0073] During specific implementation, the second driving mechanism 90 is installed on the side inside the first heat insulation cover 60 and is arranged in parallel with the first driving mechanism 50, and the two do not interfere with each other. It can be understood that the second driving mechanism 90 can adopt the same structure as the first driving mechanism 50 to drive the temperature measuring plate 91 to reciprocate. When the temperature of the medicine liquid needs to be measured, the second driving mechanism 90 drives the temperature measuring plate 91 to move toward the first refrigeration plate 20 until it and the first refrigeration plate 20 jointly squeeze the medicine liquid bag 100. At this time, the temperature sensor 92 is in full contact with the medicine liquid bag 100, and can monitor the temperature of the medicine liquid in real time, and transmit the data to the control system, so that the operator can adjust the refrigeration strategy according to the actual situation and realize precise temperature control, that is, the temperature measuring mechanism is independent of the movement of the second refrigeration plate 30, and the two do not interfere with each other, which not only ensures the accuracy of the temperature measurement, but also does not affect the mixing effect.

[0074] In some embodiments, Figure 1 and Figure 2 As shown, the suspension bracket 10 includes:

[0075] A weighing device 11, used for weighing the liquid medicine;

[0076] The hook 12 is installed on the weighing device 11 and is used to hang the medicine bag 100 .

[0077] In specific implementation, the hook 12 can be made of stainless steel, and the shape of the hook 12 can be designed according to the size and shape of the medicine bag 100 to ensure that the medicine bag 100 can be firmly hung on the weighing device 11, and the weighing device 11 can be a high-precision electronic scale, such as a weighing sensor with an accuracy of 0.1 grams, installed on the suspension bracket 10, and the weighing device 11 is connected to the control system to display and record the medicine weight data in real time.

[0078] In some embodiments, Figure 5 and Figure 6 As shown, in order to prevent the operator from accidentally touching the moving part, a protective cover 101 is also included. The protective cover 101 is fixedly connected to the first heat insulation cover 60. The suspension bracket 10 and the second refrigeration plate 30 are both located in the protective cover 101. The protective cover 101 is provided with an openable and closable isolation door 102.

[0079] In this way, the protective cover 101 can effectively isolate the external environment and prevent dust, debris, etc. from entering the interior of the device. At the same time, the moving parts such as the suspension bracket 10 and the second refrigeration plate 30 are also enclosed in the protective cover 101, which can effectively prevent the operator from accidentally touching them during the operation of the device and causing personal injury. The isolation door 102 is an openable and closable structure, such as a sliding door, a flip door, etc., which is convenient for the operator to open the protective cover 101 when needed to place or remove the medicine bag 100, clean and maintain it, and other operations.

[0080] The liquid medicine cooling and mixing device provided in this embodiment realizes efficient cooling, uniform mixing and precise temperature control of bagged liquid medicine through efficient cooling plates, reasonable heat dissipation structure and reciprocating motion of the second cooling plate driven by the driving mechanism, thereby ensuring the automation and integration of the liquid medicine processing process. The device has a simple structure and is easy to operate. The operation can be automatically completed by simply fixing the liquid medicine bag and setting parameters, which effectively solves the shortcomings of the relevant technology and has broad application prospects.

[0081] In the description of the present invention, it should be noted that the terms "vertical", "up", "down", "horizontal", etc. indicate orientations or positional relationships based on the orientations or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation on the present invention.

[0082] In the description of the present invention, it is also necessary to explain that, unless otherwise clearly specified and limited, the terms "set", "install", "connect", and "connect" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection, or it can be indirectly connected through an intermediate medium, or it can be the internal communication of two components. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0083] Finally, it should be noted that the above description is only a preferred embodiment of the utility model and is not intended to limit the utility model. Although the utility model is described in detail with reference to the above embodiments, those skilled in the art can still modify the technical solutions recorded in the above embodiments or replace some of the technical features therein by equivalents. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the utility model shall be included in the protection scope of the utility model.

Claims

1. A liquid medicine cooling and mixing device, characterized in that: include: A suspension bracket, used to fix the liquid medicine bag; The first refrigeration plate is used to reduce the temperature of the medicine liquid in the medicine bag; A second refrigeration plate is arranged opposite to the first refrigeration plate, and an accommodating space is formed between the second refrigeration plate and the first refrigeration plate; A first driving mechanism, used for driving the second refrigeration plate to reciprocate relative to the first refrigeration plate; When the second refrigeration plate reciprocates relative to the first refrigeration plate, the medicine liquid bag placed in the accommodating space is repeatedly pressed toward the first refrigeration plate to achieve cooling and mixing of the medicine liquid.

2. The liquid medicine cooling and mixing device according to claim 1, characterized in that: Also includes: A first heat-insulating cover is connected to the first refrigeration plate and encloses a first heat-dissipating cavity; A second heat-insulating cover is connected to the second refrigeration plate and encloses a second heat-dissipating cavity; A first heat dissipation fan is disposed in the first heat dissipation cavity; A second heat dissipation fan is disposed in the second heat dissipation cavity; A heat dissipation pipe connecting the first heat dissipation cavity and the second heat dissipation cavity; The second cooling fan is configured to transport the heat generated by the refrigeration of the second refrigeration plate to the first cooling cavity through the cooling pipe; the first heat insulation cover is provided with a cooling port, which is used to discharge the heat in the first cooling cavity.

3. The liquid medicine cooling and mixing device according to claim 2, characterized in that: A plurality of guide cylinders are arranged in the first heat insulation cover, and the heat dissipation pipe is slidably matched with the guide cylinders; one end of the heat dissipation pipe extends out of the first heat insulation cover and is connected to the second heat insulation cover to connect the first heat dissipation cavity with the second heat dissipation cavity.

4. The liquid medicine cooling and mixing device according to claim 3, characterized in that: The first driving mechanism is disposed in the first heat insulation cover and connected to all the heat dissipation tubes. The first driving mechanism is used to synchronously drive all the heat dissipation tubes to drive the second refrigeration plate to move horizontally back and forth relative to the first refrigeration plate.

5. The liquid medicine cooling and mixing device according to claim 2, characterized in that: The heat dissipation port is equipped with an exhaust fan.

6. The liquid medicine cooling and mixing device according to claim 1, characterized in that: Also includes: A second driving mechanism is disposed in the first heat insulation cover and is used to provide a driving force; The temperature measuring plate is arranged opposite to the first refrigeration plate and is configured to reciprocate relative to the first refrigeration plate under the drive of the second driving mechanism; A temperature sensor is arranged on the temperature measuring board; When the temperature measuring plate and the first refrigeration plate squeeze the medicine liquid bag, the temperature sensor detects the temperature of the medicine liquid.

7. The liquid medicine cooling and mixing device according to claim 1, characterized in that: The suspension support comprises: a weighing device for weighing the weight of the liquid medicine; A hook is installed on the weighing device and is used to hang the medicine liquid bag.

8. The liquid medicine cooling and mixing device according to claim 1, characterized in that: The first refrigeration plate and the second refrigeration plate are both semiconductor refrigeration plates, and heat dissipation fins are arranged thereon.

9. The liquid medicine cooling and mixing device according to any one of claims 1 to 8, characterized in that: It also includes a protective cover, which is fixedly connected to the first heat insulation cover. The suspension bracket and the second refrigeration plate are both located in the protective cover, and the protective cover is provided with an openable and closable isolation door.

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