Device for automatic leaching during column passing

Abstract

The utility model discloses a device for automatic leaching during column passing, which relates to the technical field of experimental instruments and comprises a test tube, a liquid reaction space is formed in the test tube, and an opening is formed in the upper part of the test tube; the container is arranged on one side of the test tube, and a certain amount of leacheate is injected into the container; the sealing plug is hermetically connected in an opening formed in the upper part of the test tube, a drainage tube extending into the test tube is connected in the sealing plug in a penetrating manner, one end, far away from the sealing plug, of the drainage tube is positioned in the container, and a second valve is mounted on the surface of the drainage tube; according to the utility model, the test tube is connected with the container filled with the leacheate through the drainage tube, and the drainage tube and the test tube are sealed through the sealing plug, so that negative pressure can be formed in the chromatographic column when a material phase reacts and passes through the column; therefore, the leacheate in the container can be sucked into the chromatographic column for automatic leaching by the drainage tube, and the conditions that personnel need to frequently add and operate by themselves and are not easy to control are avoided.

Description

Technical Field

[0001] The utility model relates to the technical field of experimental instruments, in particular to a device for automatic elution during column passing. Background Art

[0002] Column chromatography is a commonly used method for separating mixtures. It utilizes the differences in the physical and chemical properties of the components in the mixture (such as adsorption capacity, molecular size, molecular interaction force, distribution coefficient, etc.) to make the distribution of the components in the stationary phase and the mobile phase different, so that the components move at different speeds to achieve the purpose of separation.

[0003] Reference is made to the existing patent publication number: CN212818279U, an automatic elution device for extraction and separation of traditional Chinese medicine, including a placement rack, on which several solvent bottles are placed, a numerical control panel is arranged on the upper part of the placement rack, a bottle stopper is arranged on the solvent bottle, a pipette runs through the bottle stopper, the bottom end of the pipette is located at the bottom of the solvent bottle, and the upper end of the pipette is connected to a solenoid valve. The utility model can freely select different solvents for elution, and can automatically add liquid in a quantitative manner, which changes the traditional manual liquid addition method, saves the physical strength of the experimenters, saves time, and reduces errors.

[0004] However, in the existing experimental separation process, the current situation is that when performing the elution operation, the experimenter usually manually adds the eluent, the elution speed cannot be controlled, the elution effect may not achieve the expected effect, and when the solution is separated, the mixing effect is poor, resulting in insufficient solution reaction and low efficiency. Utility Model Content

[0005] The purpose of the utility model is to solve the shortcomings of the prior art and propose a device for automatic elution when passing through a column. The utility model connects a test tube with a container containing an eluent through a drainage tube, and the drainage tube and the test tube are sealed by a sealing plug. When the material phase reacts to pass through the column, a negative pressure can be formed in the chromatography column, so that the drainage tube can suck the eluent in the container into the chromatography column for automatic elution, thereby avoiding the need for personnel to frequently add operations and difficult to control situations.

[0006] In order to achieve the above purpose, the utility model adopts the following technical solutions:

[0007] A device for automatic elution during column flow, comprising:

[0008] A test tube having a liquid reaction space therein and an opening at the top;

[0009] a container, which is constructed on one side of the test tube and filled with a certain amount of eluent;

[0010] A sealing plug, which is sealed and connected to an opening formed on the upper part of the test tube, a drainage tube extending into the test tube is connected through the interior of the sealing plug, and one end of the drainage tube away from the sealing plug is located in the container, and a second valve is installed on the surface of the drainage tube;

[0011] The test tube is internally structured with a flow guide component, and the test tube is internally provided with a cleaning component located below the flow guide component.

[0012] The utility model is further configured that the sealing plug is configured so that one end can be gradually inclined inwardly along the radial direction.

[0013] The utility model is further configured that the guide assembly includes: a connecting member, a rotating member and blades;

[0014] The connecting member is horizontally connected to one end of the drainage tube located in the test tube, the rotating member is rotatably connected to the surface of the connecting member, and a plurality of blades are arranged on one end of the rotating member away from the connecting member.

[0015] The utility model is further configured such that the flow guide component is located below the flow guide pipe, and the blades are arranged in an irregular fan shape.

[0016] The utility model is further configured that the cleaning assembly includes: a floating body, a through hole and a counterweight;

[0017] The float is arranged inside the test tube, the counterweight is connected to the lower part of the float, and the through holes are arranged to penetrate and be opened on the surface of the float in an inclined downward manner.

[0018] The utility model is further configured that the lower structure of the float is arranged in an arc shape, and the float is in contact with the inside of the test tube.

[0019] The utility model is further configured that the counterweight is configured so that the gravity is smaller than the buoyancy of the float in the test tube.

[0020] The utility model is further configured that the lower part of the test tube is connected with a liquid discharge part, and a first valve is installed on the surface of the liquid discharge part.

[0021] The beneficial effects of the utility model are as follows: the utility model connects the test tube and the container containing the eluent through a drainage tube, and the drainage tube and the test tube are sealed by a sealing plug. When the material phase reacts through the column, a negative pressure can be formed in the chromatography column, so that the drainage tube can suck the eluent in the container into the chromatography column for automatic elution, thereby avoiding the need for personnel to frequently add operations and situations that are difficult to control.

[0022] 1. The device for automatic elution during column passage is provided with a sealing plug and a drainage tube in cooperation. Since a container containing an eluent is provided on one side of the test tube, when the substance in the test tube is reacting, the test tube can be connected to the container containing the eluent through the drainage tube. The drainage tube and the test tube are sealed by the sealing plug. When the material reacts and passes through the column, a negative pressure can be formed in the chromatography column, so that the drainage tube can suck the eluent in the container into the chromatography column for automatic elution, thereby avoiding the need for personnel to frequently add operations and the situation that is difficult to control, which is more convenient.

[0023] 2. The device for automatic elution during column flow is provided with a connecting member, a rotating member and blades. When a negative pressure is formed in the test tube, the eluent in the container is drained into the test tube, and the eluent can flow under the fan-shaped blades. When the eluent exerts pressure on the blades, the blades can rotate under the action of the rotating member to perform a large-scale spraying treatment, thereby increasing the contact area and mixing effect between the eluent and the solution in the test tube, thereby improving the reaction efficiency.

[0024] 3. The device for automatic elution during column passing is provided with a cleaning component. When conducting experiments through a test tube, a certain amount of residual material is likely to remain inside. When the material is discharged, the float can move downward with the liquid level and be pulled under the action of the counterweight. The float is in contact with the inside of the test tube, so that the float can better scrape off the residual material remaining in the test tube during the downward movement, thereby improving the cleaning effect. BRIEF DESCRIPTION OF THE DRAWINGS

[0025] Figure 1 This is a schematic diagram of the overall structure of a device for automatic elution during column passing proposed by the utility model;

[0026] Figure 2 This is a schematic diagram of the overall front section structure of a device for automatic elution during column passing proposed by the utility model;

[0027] Figure 3 The utility model provides a device for automatic elution during column passing. Figure 2 Schematic diagram of the enlarged structure at point A in the middle.

[0028] In the figure: 1. test tube; 2. container; 3. drainage part; 4. first valve; 5. sealing plug; 6. drainage tube; 7. second valve; 8. blade; 9. counterweight; 10. float; 11. through hole; 12. rotating part; 13. connecting part. DETAILED DESCRIPTION

[0029] The technical solution of this patent is further described in detail below in conjunction with specific implementation methods.

[0030] The embodiments of the present invention are described in detail below, and examples of the embodiments are shown in the accompanying drawings, wherein the same or similar reference numerals throughout represent the same or similar elements or elements having the same or similar functions. The embodiments described below with reference to the accompanying drawings are exemplary and are only used to explain the present invention, and cannot be understood as limiting the present invention.

[0031] In the description of this patent, it should be understood that the terms "center", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", etc., indicating the orientation or position relationship, are based on the orientation or position relationship shown in the drawings, and are only for the convenience of describing this patent and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation on this patent.

[0032] In the description of this patent, it should be noted that, unless otherwise clearly specified and limited, the terms "installed", "connected", "connected", and "set" should be understood in a broad sense, for example, it can be fixedly connected or set, or it can be detachably connected or set, or connected or set in one piece. For ordinary technicians in this field, the specific meanings of the above terms in this patent can be understood according to specific circumstances.

[0033] Reference Figure 1-3 , a device for automatic elution during column flow, comprising: a test tube 1, which has a liquid reaction space inside and an opening at the top, so that reactants can be added into the test tube 1 through the opening to conduct experiments in the test tube 1; a container 2, which is constructed on one side of the test tube 1 and filled with a certain amount of eluent; a sealing plug 5, which is sealed and connected to the opening at the top of the test tube 1, a drainage tube 6 extending into the test tube 1 is connected to the inside of the sealing plug 5, and the end of the drainage tube 6 away from the sealing plug 5 is located in the container 2, and a second valve 7 is installed on the surface of the drainage tube 6, the test tube 1 is connected to the container 2 containing the eluent through the drainage tube 6, and the drainage tube 6 and the test tube 1 are connected by a sealing The plug 5 is sealed, and when the material phase reacts through the column, a negative pressure can be formed in the chromatography column. The second valve 7 is opened, so that the drainage tube 6 can suck the eluent in the container 2 into the chromatography column for automatic elution, so as to avoid the need for personnel to frequently add operations and difficult to control situations, which is more convenient; the internal structure of the test tube 1 is equipped with a guide component, through which the eluent can be guided to flow to a certain extent, and the elution range of the eluent can be increased, thereby improving the mixing reaction effect. The interior of the test tube 1 is provided with a cleaning component located below the guide component, through which the interior of the test tube 1 after the test can be conveniently cleaned to a certain extent, thereby reducing the residue and reducing the difficulty of cleaning for personnel.

[0034] Furthermore, the sealing plug 5 is configured so that one end can be gradually tilted inward along the radial direction. Through this design, when the sealing plug 5 is connected to the test tube 1, the inclined end of the sealing plug 5 can gradually come into close contact with the test tube 1, thereby reducing the gap and improving the connection strength and tightness.

[0035] Specifically, refer to Figure 2 The guide assembly includes: a connecting member 13, a rotating member 12 and blades 8; the connecting member 13 is horizontally connected to one end of the drainage tube 6 located in the test tube 1, the rotating member 12 is rotatably connected to the surface of the connecting member 13, and the blades 8 are constructed with multiple blades, all of which are installed on the end of the rotating member 12 away from the connecting member 13. Through this embodiment, when the eluent is drained into the test tube 1, the eluent can flow on the fan-shaped blades 8, and when the eluent exerts pressure on the blades 8, the blades 8 can rotate under the action of the rotating member 12 to perform a large-scale spraying treatment, thereby increasing the contact area and mixing effect between the eluent and the solution in the test tube 1, thereby improving the reaction efficiency.

[0036] Furthermore, the guide component is located below the drainage tube 6, and the blades 8 are arranged in an irregular fan shape. Through this design, the eluent can pass through the through holes 11 on the surface of the float 10 when flowing, so as to guide the eluent in advance and increase the spraying range. Since the downward flowing eluent has a certain downward force, the irregular fan shape of the blades 8 can better drive the blades 8 to move, thereby improving the rotation effect.

[0037] Specifically, refer to Figure 2-3 The cleaning assembly includes: a float 10, a through hole 11 and a counterweight 9; the float 10 is arranged inside the test tube 1, the counterweight 9 is connected to the lower part of the float 10, and the through holes 11 are all arranged obliquely downward to penetrate the surface of the float 10. Through this embodiment, when the substance is discharged, the float 10 can move downward with the liquid level and be pulled under the action of the counterweight 9. Furthermore, the lower part of the float 10 is structured in an arc shape, so that the arc-shaped float 10 can better allow the eluent to pass through and avoid the difficulty of liquid flow, and the float 10 is in contact with the inside of the test tube 1, so that the float 10 can better scrape off the residual material remaining in the test tube 1 during the downward movement, thereby improving the cleaning effect.

[0038] Furthermore, the counterweight 9 is configured so that its gravity is smaller than the buoyancy of the float 10 in the test tube 1. With this design, the float 10 can float on the liquid surface in the test tube 1 only when the gravity of the counterweight 9 is smaller than the buoyancy of the float 10 in the test tube 1. At this time, the float 10 can clean up the residual material within the liquid surface height range from top to bottom. On the contrary, if the gravity of the counterweight 9 is greater than the buoyancy of the float 10 in the test tube 1, the float 10 will directly sink into the solution, which will not only affect the experiment but also have a poor cleaning effect.

[0039] Specifically, refer to Figure 1-2 The lower part of the test tube 1 is connected to a drainage part 3, and a first valve 4 is installed on the surface of the drainage part 3. Through this embodiment, by adjusting the opening and closing of the first valve 4, the reaction time of the reactant and the eluent in the test tube 1 can be accurately controlled. When the reaction is completed, the first valve 4 is opened, and the product in the test tube 1 can flow out through the drainage part 3, which is convenient for subsequent processing.

[0040] Working principle: When using the utility model, first add the substance to be tested into the test tube 1, then place the float 10 and the counterweight 9 together in the test tube 1, so that the float 10 can float on the liquid surface, and then when the substance in the test tube 1 is reacting, the test tube 1 can be connected to the container 2 containing the eluent through the drainage tube 6, and the drainage tube 6 and the test tube 1 are sealed by the sealing plug 5. When the material phase reacts through the column, a negative pressure can be formed in the chromatography column, so that the drainage tube 6 can suck the eluent in the container 2 into the chromatography column for automatic elution, so as to avoid the need for personnel to frequently add operations and difficult to control situations. It is more convenient, because the negative pressure is formed in the test tube 1, the eluent in the container 2 is sucked into the chromatography column When the liquid is drained into the test tube 1, the eluent can flow on the fan-shaped blades 8, and when the eluent exerts pressure on the blades 8, the blades 8 can rotate under the action of the rotating member 12. At this time, the eluent passes through the through holes 11 on the surface of the float 10 to perform a large-scale spraying treatment, thereby increasing the contact area and mixing effect between the eluent and the solution in the test tube 1, thereby improving the reaction efficiency. Subsequently, when the substance is discharged, the float 10 can move downward with the liquid level and be pulled under the action of the counterweight 9, while the float 10 is in contact with the inside of the test tube 1, so that the float 10 can better scrape off the residual material remaining in the test tube 1 during the downward movement, thereby improving the cleaning effect.

[0041] The above are only preferred specific implementation methods of the utility model, but the protection scope of the utility model is not limited to this. Any technician familiar with the technical field within the technical scope disclosed by the utility model, who makes equivalent replacements or changes based on the technical scheme and utility model concept of the utility model, should be covered by the protection scope of the utility model.

Claims

1. A device for automatic elution during column washing, characterized in that: include: A test tube (1) having a liquid reaction space inside and an opening at the top; A container (2), which is constructed on one side of the test tube (1) and filled with a certain amount of eluent; a sealing plug (5) which is sealingly connected to an opening formed at the upper portion of the test tube (1); a drainage tube (6) extending into the test tube (1) is connected through the interior of the sealing plug (5); an end of the drainage tube (6) away from the sealing plug (5) is located in the container (2); a second valve (7) is installed on the surface of the drainage tube (6); The test tube (1) is internally structured with a flow guide component, and the test tube (1) is internally provided with a cleaning component located below the flow guide component.

2. The device for automatic elution during column flow according to claim 1, characterized in that: The sealing plug (5) is configured so that one end can be gradually tilted inwards along the radial direction.

3. The device for automatic elution during column flow according to claim 1, characterized in that: The flow guide assembly comprises: a connecting member (13), a rotating member (12) and blades (8); The connecting member (13) is horizontally connected to one end of the drainage tube (6) located in the test tube (1), the rotating member (12) is rotatably connected to the surface of the connecting member (13), and the blades (8) are constructed with a plurality of blades, each of which is mounted on one end of the rotating member (12) away from the connecting member (13).

4. The device for automatic elution during column flow according to claim 3, characterized in that: The flow guide component is located below the flow guide pipe (6), and the blades (8) are arranged in an irregular fan shape.

5. The device for automatic elution during column flow according to claim 1, characterized in that: The cleaning assembly comprises: a floating body (10), a through hole (11) and a counterweight (9); The float (10) is arranged inside the test tube (1), the counterweight (9) is connected to the lower part of the float (10), and the through holes (11) are all arranged to penetrate the surface of the float (10) in an inclined downward direction.

6. The device for automatic elution during column flow according to claim 5, characterized in that: The lower structure of the float (10) is arranged in an arc shape, and the float (10) is in contact with the inside of the test tube (1).

7. The device for automatic elution during column flow according to claim 5, characterized in that: The counterweight (9) is configured such that the gravity thereof is smaller than the buoyancy force exerted on the float (10) in the test tube (1).

8. The device for automatic elution during column flow according to claim 1, characterized in that: The lower part of the test tube (1) is connected to a liquid discharge part (3), and a first valve (4) is installed on the surface of the liquid discharge part (3).

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