Automatic gas-liquid conveying and metering control system for adhesive of boiling granulation dryer

By designing an automatic gas-liquid delivery metering control system, the quality problems of the binder delivery system and the poor control of atomization gas pressure in the vertical fluidized bed boiling drying granulator are solved, and high-quality drug pellet production is achieved and production costs are reduced.

CN222778027UActive Publication Date: 2025-04-22SICHUAN JIAMA MECHANICAL MFG CO LTD +1
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Patent Information

Application Number
CN202420959080.2
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-05-07
Publication Date
2025-04-22
Estimated Expiration
2034-05-07

AI Technical Summary

Technical Problem

During the production process of drug particles in the existing vertical fluidized bed boiling drying granulator, the adhesive delivery system has problems such as metal wear, colloidal powder not falling off and leaking, which affects the quality of the drug, and the atomization gas pressure is poorly controlled, resulting in uneven particle size, different colors, and high costs.

Method used

An automatic gas-liquid delivery metering control system was designed, and through components such as liquid storage tanks, infusion pumps, liquid flow sensors, fine-tuning valves, atomization electrical proportional valves and gas flow sensors, reliable control of atomization gas pressure and adhesive liquid supply volume is achieved to ensure the perfect matching of the gas-liquid ratio.

Benefits of technology

The system can effectively prevent metal wear and colloidal powder from falling off in the adhesive, reduce leakage risks, improve the quality of the finished product of the pellet, and reduce production costs. At the same time, by precisely controlling the atomization gas pressure and liquid supply, we ensure that the particle size is consistent and the color is uniform, and the traceability of the product is improved.

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Patent Text Reader

Abstract

The utility model discloses an automatic gas-liquid conveying and metering control system for an adhesive of a boiling granulation dryer, which comprises a liquid storage tank, a liquid outlet of the liquid storage tank is connected with a liquid supply interface of a spray gun through a liquid supply pipe, and an atomizing gas interface of the spray gun is connected with a gas outlet of a gas storage tank through an atomizing gas pipe; the air outlet of the air storage tank is also connected with the air inlet of the liquid storage tank through an air inlet pipe; a slurry adding opening of the liquid storage tank is connected with a liquid conveying pump through a slurry adding pipe. The device has the beneficial effects that the pressure of atomization gas can be reliably controlled, a perfect proportion of the atomization gas pressure to the liquid supply amount is formed, the consistency of production conditions of batches of like product particles is ensured, and the quality of finished particles is improved; reworking or scrapping of product particles during production is prevented, and the production cost is reduced; and data recording can be carried out on the atomization gas consumption and pressure, and traceability of particles is guaranteed.
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Description

Technical Field

[0001] The utility model relates to the technical field of boiling drying granulation, in particular to an automatic gas-liquid conveying metering control system for a boiling granulation dryer adhesive. Background Art

[0002] Vertical fluidized bed boiling granulation dryer is a kind of equipment used in the pharmaceutical field, which can produce drug granules. The drug powder is loaded into the granulator and fluidized and boiled, and at the same time, it combines with the drug binder droplets atomized by the atomization system to form particles. The drug powder is suspended in the granulator through the spray gun and combines with the drug binder droplets sprayed by the atomizer to form particles. Therefore, the uniformity of the atomization of the binder or liquid becomes the key to the granulation operation.

[0003] At present, in the process of making drug particles, the atomization system of the vertical fluidized bed boiling drying granulator relies on a gear pump or a peristaltic pump to transport the adhesive to the spray gun, and the adhesive is atomized by the atomizing gas. When the gear pump works at a high speed, metal pins will fall off and mix into the adhesive, affecting the quality of the final drug product. When the peristaltic pump is working, the roller rolls for a long time to compress the infusion hose, which will produce colloidal powder that has not fallen off and mixes into the adhesive, affecting the quality of the drug. It is easy to break and leak, affecting the environment, and the later use cost of the gear pump or peristaltic pump is quite high.

[0004] At the same time, the current atomization system relies on manual adjustment of the atomizing gas pressure, and is unable to reliably control the atomizing gas pressure, resulting in the inability to form a perfect ratio between the atomizing gas pressure and the liquid supply volume, ultimately causing the particles to be uneven in size and color, and the particle quality to not meet the standards. It is also impossible to reliably control and record the data of the atomizing gas dosage and pressure. Utility Model Content

[0005] The purpose of the utility model is to provide an automatic gas-liquid conveying metering control system for a fluidized bed granulating dryer adhesive, which can reliably control the atomizing gas pressure, form a perfect ratio between the atomizing gas pressure and the liquid supply, improve the quality of the finished granules, and reliably control and record the atomizing gas dosage and pressure.

[0006] The automatic gas-liquid conveying metering control system of the fluidized bed granulating dryer adhesive comprises a liquid storage tank, the liquid outlet of the liquid storage tank is connected to the liquid supply interface of the spray gun through a liquid supply pipe, and the atomizing gas interface of the spray gun is connected to the gas outlet of the gas storage tank through an atomizing gas pipe;

[0007] The air outlet of the gas storage tank is also connected to the air inlet of the liquid storage tank through an air inlet pipe;

[0008] The slurry adding port of the liquid storage tank is connected with an infusion pump through a slurry adding pipe.

[0009] The above structure clears the atomizing gas and adhesive liquid delivery channels, thereby achieving adhesive atomization and adhesive delivery.

[0010] Furthermore, a fine-tuning valve is provided on the liquid supply pipe, the inlet of the fine-tuning valve is connected to the liquid outlet of the liquid storage tank, and the outlet of the fine-tuning valve is communicated with the liquid supply interface of the spray gun;

[0011] A liquid flow sensor is provided on the liquid supply pipe between the liquid outlet of the liquid storage tank and the fine-tuning valve;

[0012] The liquid outlet of the liquid storage tank is also provided with a tank bottom valve.

[0013] Furthermore, the air outlet of the gas storage tank is connected to the air source inlet of the atomizing electrical proportional valve; the air source outlet of the atomizing electrical proportional valve is connected to the inlet of the two-position two-way solenoid valve of the liquid storage tank, and the outlet of the two-position two-way solenoid valve of the liquid storage tank is connected to the air inlet of the liquid storage tank through an air inlet pipe;

[0014] The gas source outlet of the atomizing electric proportional valve is also connected to the inlet of the two-position two-way solenoid valve of the spray gun, and the outlet of the two-position two-way solenoid valve of the spray gun is connected to the atomizing gas interface of the spray gun through an atomizer pipe;

[0015] A gas flow sensor is arranged between the gas outlet of the gas storage tank and the gas source inlet of the atomizing electric proportional valve.

[0016] The gas flow sensor and the liquid flow sensor are connected to the first receiving end and the second receiving end of the control system respectively, and the atomizing electrical proportional valve, the fine-tuning valve and the tank bottom valve are connected to the first control end, the second control end and the third control end of the control system respectively.

[0017] The gas flow sensor and the liquid flow sensor can feed back the collected gas flow data and liquid flow data to the control system, and adjust the proportional opening of the atomizing electrical proportional valve, the tank bottom valve and the fine-tuning valve according to the gas flow data and the liquid flow data in the control system. That is, when the liquid supply increases or decreases, the control system automatically reduces or increases the opening of the tank bottom valve and the fine-tuning valve to adjust the balance of the liquid supply. At the same time, the atomizing electrical proportional valve automatically adjusts the opening size under the action of the liquid supply data to accurately control the ratio of gas to liquid, thereby ensuring that the atomized droplets are always uniform.

[0018] Furthermore, an automatic slurry adding valve is provided at the slurry adding port of the liquid storage tank, and the automatic slurry adding valve is connected to the infusion pump through a slurry adding pipe.

[0019] The automatic slurry adding valve and the infusion pump are connected to the seventh control terminal and the eighth control terminal of the control system respectively.

[0020] Furthermore, a feed vacuum valve is provided at the feed inlet of the liquid storage tank; the feed vacuum valve is connected to the fourth control terminal of the control system;

[0021] An automatic exhaust ball valve is provided at the exhaust port of the liquid storage tank, and the automatic exhaust ball valve is connected to the fifth control terminal of the control system;

[0022] A safety valve is arranged on the top of the liquid storage tank; the safety valve is connected to the sixth control terminal of the control system.

[0023] Furthermore, a pressure sensor and a liquid level sensor are also provided on the top of the liquid storage tank, and the pressure sensor and the liquid level sensor are respectively connected to the third receiving end and the fourth receiving end of the control system;

[0024] A temperature sensor is also provided at the bottom of the liquid storage tank, and the temperature sensor is connected to the fifth receiving end of the control system.

[0025] The liquid level sensor can feed back the collected liquid level data of the liquid storage tank to the control system. The control system automatically controls the start and stop of the feed vacuum valve, automatic slurry adding valve and infusion pump according to the liquid level data of the liquid storage tank to ensure that there is sufficient adhesive in the liquid storage tank.

[0026] The pressure sensor can feed back the collected pressure data of the liquid storage tank to the control system. The control system controls the opening and closing of the automatic exhaust ball valve according to the pressure data of the liquid storage tank. That is, when the pressure is over, the automatic exhaust valve automatically opens, and when the pressure is under, the automatic exhaust valve automatically closes, so as to achieve the purpose of stable liquid supply.

[0027] At the same time, when the pressure data of the liquid storage tank exceeds the normal exhaust range, the control system will automatically open the safety valve to prevent the air pressure in the liquid storage tank from being too high or too low, causing adhesive leakage; after the pressure data of the liquid storage tank returns to normal, the control system will automatically close the safety valve and the atomization system will resume operation.

[0028] Furthermore, the gas storage tank, the atomizing electrical proportional valve, the two-position two-way solenoid valve of the liquid storage tank and the two-position two-way solenoid valve of the spray gun are all arranged in a control box.

[0029] Furthermore, the liquid storage tank and the control box are all installed on the mobile vehicle body.

[0030] The above structure enables the atomization system to be movable, facilitates the free combination of the atomization system with other equipment, and improves the practicality of the atomization system.

[0031] Beneficial effects: 1. It can reliably control the atomizing gas pressure, form a perfect ratio between the atomizing gas pressure and the liquid supply, ensure the consistency of production conditions between batches of similar product particles, and improve the quality of the finished particles;

[0032] 2. Prevent rework or scrapping of product particles and reduce production costs;

[0033] 3. Able to record the amount and pressure of atomizing gas to ensure the traceability of particles;

[0034] 4. Reduce human resource waste and reduce human resource costs;

[0035] 5. It can reduce the risk of damage to the gas-liquid transportation system, reduce the risk of leakage, and reduce environmental impact. BRIEF DESCRIPTION OF THE DRAWINGS

[0036] Figure 1 It is a plan view of the utility model;

[0037] Figure 2 This is a PLC connection diagram. DETAILED DESCRIPTION

[0038] The specific implementation manner and working principle of the utility model are further described in detail below with reference to the accompanying drawings.

[0039] like Figure 1-Figure 2 As shown, the automatic gas-liquid conveying metering control system of the adhesive of the boiling granulation dryer includes a mobile body 1, on which a control box 2 and a liquid storage tank 3 are installed;

[0040] The liquid outlet of the liquid storage tank 3 is connected to the liquid supply interface of the spray gun 4 through a liquid supply pipe; a fine-tuning valve 39 is provided on the liquid supply pipe, the inlet of the fine-tuning valve 39 is communicated with the liquid outlet of the liquid storage tank 3, and the outlet of the fine-tuning valve 39 is communicated with the liquid supply interface of the spray gun 4;

[0041] A liquid flow sensor 38 is provided on the liquid supply pipe between the liquid outlet of the liquid storage tank 3 and the fine-tuning valve 39;

[0042] The liquid outlet of the liquid storage tank 3 is also provided with a tank bottom valve 37;

[0043] The liquid flow sensor 38 is connected to the first receiving end and the second receiving end of the control system, and the fine-tuning valve 39 and the tank bottom valve 37 are connected to the second control end and the third control end of the control system respectively;

[0044] An automatic slurry adding valve 35 is provided at the slurry adding port of the liquid storage tank 3, and the automatic slurry adding valve 35 is connected to the liquid infusion pump 5 through a slurry adding pipe; the automatic slurry adding valve 35 and the liquid infusion pump 5 are respectively connected to the seventh control terminal and the eighth control terminal of the control system;

[0045] A feed vacuum valve 30 is provided at the feed inlet of the liquid storage tank 3; the feed vacuum valve 30 is connected to the fourth control terminal of the control system;

[0046] An automatic exhaust ball valve 31 is provided at the exhaust port of the liquid storage tank 3, and the automatic exhaust ball valve 31 is connected to the fifth control terminal of the control system;

[0047] A safety valve 33 is provided on the top of the liquid storage tank 3; the safety valve 33 is connected to the sixth control terminal of the control system;

[0048] A pressure sensor 32 and a liquid level sensor 34 are also provided on the top of the liquid storage tank 3, and the pressure sensor 32 and the liquid level sensor 34 are respectively connected to the third receiving end and the fourth receiving end of the control system;

[0049] A temperature sensor 36 is also provided at the bottom of the liquid storage tank 3 , and the temperature sensor 36 is connected to the fifth receiving end of the control system.

[0050] The control box 2 is provided with a gas storage tank 21, a gas flow sensor 22, an atomizing electrical proportional valve 23, a two-position two-way solenoid valve 24 for a liquid storage tank and a two-position two-way solenoid valve 25 for a spray gun;

[0051] The gas outlet of the gas storage tank 21 is connected to the gas source inlet of the atomizing electrical proportional valve 23; the gas source outlet of the atomizing electrical proportional valve 23 is respectively connected to the inlet of the two-position two-way solenoid valve 24 of the liquid storage tank and the inlet of the two-position two-way solenoid valve 25 of the spray gun;

[0052] The outlet of the two-position two-way solenoid valve 24 of the liquid storage tank is connected to the air inlet of the liquid storage tank 3 through an air inlet pipe, and the outlet of the two-position two-way solenoid valve 25 of the spray gun is connected to the atomizing gas interface of the spray gun 4 through an atomizer pipe;

[0053] A gas flow sensor 22 is provided between the gas outlet of the gas storage tank 21 and the gas source inlet of the atomizing electrical proportional valve 23;

[0054] The gas flow sensor 22 is connected to a first receiving end of the control system, and the atomizing electrical proportional valve 23 is connected to a first control end of the control system.

[0055] Through the above-mentioned device, the gas flow sensor 22 and the liquid flow sensor 38 can feed back the collected gas flow data and liquid flow data to the PLC, and perform PID operation in the PLC. At the same time, according to the proportional value after the operation, the proportional openings of the atomizing electrical proportional valve 23, the fine-tuning valve 39, and the tank bottom valve 37 are adjusted respectively. That is, when the liquid supply increases or decreases, the control system automatically reduces or increases the openings of the tank bottom valve 37 and the fine-tuning valve 39 to adjust the balance of the liquid supply. At the same time, the atomizing electrical proportional valve automatically adjusts the opening size under the action of the liquid supply data to accurately control the ratio of gas and liquid, thereby ensuring that the atomized droplets are always uniform.

[0056] The liquid level sensor 34 can feed back the collected liquid level data of the liquid storage tank to the PLC. The PLC controls the start and close of the feed vacuum valve 30, the automatic slurry adding valve 35 and the infusion pump 5 according to the liquid level data of the liquid storage tank, and replenishes them in time to ensure that there is sufficient adhesive in the liquid storage tank 3.

[0057] The pressure sensor 32 can feed back the collected liquid storage tank pressure data to the PLC, and the PLC controls the opening and closing of the automatic exhaust ball valve 31 according to the liquid storage tank pressure data. That is, when overpressure occurs, the automatic exhaust valve automatically opens, and when underpressure occurs, the automatic exhaust valve automatically closes, thereby achieving the purpose of stable liquid supply.

[0058] At the same time, when the pressure data of the liquid storage tank exceeds the normal exhaust range, the control system will automatically open the safety valve 33 to prevent the gas pressure in the liquid storage tank 3 from being too high or too low, causing adhesive leakage; after the pressure data of the liquid storage tank returns to normal, the control system will automatically close the safety valve 33, and the gas-liquid transportation system will resume operation.

Claims

1. An automatic gas-liquid conveying metering control system for a fluidized bed granulation dryer adhesive, characterized in that: It comprises a liquid storage tank (3), the liquid outlet of the liquid storage tank (3) is connected to the liquid supply interface of the spray gun (4) through a liquid supply pipe, and the atomizing gas interface of the spray gun (4) is connected to the gas outlet of the gas storage tank (21) through an atomizing gas pipe; The air outlet of the air storage tank (21) is also connected to the air inlet of the liquid storage tank (3) via an air inlet pipe; The slurry feeding port of the liquid storage tank (3) is connected to an infusion pump (5) via a slurry feeding pipe.

2. The automatic gas-liquid conveying metering control system of the fluidized bed granulation dryer adhesive according to claim 1, characterized in that: The liquid supply pipe is provided with a fine-tuning valve (39), the inlet of the fine-tuning valve (39) is connected to the liquid outlet of the liquid storage tank (3), and the outlet of the fine-tuning valve (39) is communicated with the liquid supply interface of the spray gun (4); A liquid flow sensor (38) is provided on the liquid supply pipe between the liquid outlet of the liquid storage tank (3) and the fine-tuning valve (39); The liquid outlet of the liquid storage tank (3) is also provided with a tank bottom valve (37).

3. The automatic gas-liquid conveying metering control system of the fluidized bed granulation dryer adhesive according to claim 1, characterized in that: The gas outlet of the gas storage tank (21) is connected to the gas source inlet of the atomizing electrical proportional valve (23); the gas source outlet of the atomizing electrical proportional valve (23) is connected to the inlet of the two-position two-way solenoid valve (24) of the liquid storage tank, and the outlet of the two-position two-way solenoid valve (24) of the liquid storage tank is connected to the gas inlet of the liquid storage tank (3) through an air inlet pipe; The gas source outlet of the atomizing electric proportional valve (23) is also connected to the inlet of the two-position two-way solenoid valve (25) of the spray gun, and the outlet of the two-position two-way solenoid valve (25) of the spray gun is connected to the atomizing gas interface of the spray gun (4) through an atomizer pipe; A gas flow sensor (22) is provided between the gas outlet of the gas storage tank (21) and the gas source inlet of the atomizing electric proportional valve (23).

4. The automatic gas-liquid conveying metering control system of the fluidized bed granulation dryer binder according to claim 1, characterized in that: An automatic slurry adding valve (35) is provided at the slurry adding port of the liquid storage tank (3), and the automatic slurry adding valve (35) is connected to the infusion pump (5) via a slurry adding pipe.

5. The automatic gas-liquid conveying metering control system of the fluidized bed granulation dryer adhesive according to claim 4, characterized in that: A feed vacuum valve (30) is provided at the feed inlet of the liquid storage tank (3); An automatic exhaust ball valve (31) is provided at the exhaust port of the liquid storage tank (3); A safety valve (33) is provided on the top of the liquid storage tank (3).

6. The automatic gas-liquid conveying metering control system of the fluidized bed granulation dryer binder according to claim 4, characterized in that: A pressure sensor (32) and a liquid level sensor (34) are also provided on the top of the liquid storage tank (3); A temperature sensor (36) is also provided at the bottom of the liquid storage tank (3).

7. The automatic gas-liquid conveying metering control system of the fluidized bed granulation dryer binder according to claim 3, characterized in that: The gas storage tank (21), the atomizing electrical proportional valve (23), the liquid storage tank two-position two-way solenoid valve (24) and the spray gun two-position two-way solenoid valve (25) are all arranged in the control box (2).

8. The automatic gas-liquid conveying metering control system of the fluidized bed granulation dryer binder according to claim 1 or 7, characterized in that: The liquid storage tank (3) and the control box (2) are all installed on the mobile vehicle body (1).