Rapid slide stainer with liquid blowing function
By setting up an air supply module and an automatic liquid discharge and rehydration system in the fast dyeing machine, the cross-contamination and purity reduction caused by reagent residue during the glass slide staining process is solved, and a more efficient sample processing effect is achieved.
Patent Information
- Application Number
- CN202421552013.5
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-07-02
- Publication Date
- 2025-05-06
- Estimated Expiration
- 2034-07-02
AI Technical Summary
Reagent residues are prone to occur during the staining process of slides, resulting in cross-contamination of reagents and a decrease in purity, affecting the treatment effect.
A fast dyeing machine with liquid blowing function was designed. An air supply module was used to set up an air outlet above the slide rack. The fan was used to blow the remaining reagent on the slide back into the liquid tank, and the low-purity reagent was automatically discharged through the liquid discharge system and the liquid replenishment system to supplement the high-purity reagent.
It effectively reduces the cross-contamination of reagents, maintains the uniformity of reagents in the liquid tank, and improves the efficiency and effect of sample processing.
Smart Images
Figure CN222837888U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the technical field of trace sample processing equipment, in particular to an automatic slide dyeing machine for dyeing samples on slides. Background Art
[0002] The staining process of traditional glass slide samples is usually carried out manually or automatically by a robot arm and an intelligent program, that is, multiple glass slides are placed on a glass slide rack, and the glass slide rack is sent to one or more staining areas for staining by a mechanical gripper and XY axis control. In order to improve efficiency and effect, the applicant has filed a patent application entitled "A simple and fast automatic staining machine", which not only has a simple and reasonable structural design, but also has a higher degree of automation and is more convenient to operate. However, there are still some problems with the equipment. For example, a lot of reagents will remain after the glass slide is lifted out of the reagent after immersion, so cross-contamination of reagents will occur when entering other different liquid tanks of reagents, thereby affecting the effect. In addition, when the sample is soaked a certain number of times, the purity of the reagent will decrease due to the influence of the reagents remaining on the glass slide in different liquid tanks, which will further affect the treatment effect. Utility Model Content
[0003] The utility model aims at the shortcomings of the prior art and provides a rapid dyeing machine with a liquid blowing function, which has a simple structure, a more reasonable design, can reduce cross contamination of reagents, can keep the reagents in the liquid tank more uniform, has higher processing efficiency and better effect.
[0004] In order to solve the above technical problems, the utility model adopts the following technical solutions: a rapid slide staining machine with a liquid blowing function, comprising a main machine, an electric control mechanism, a plurality of liquid tanks, a moving device and a glass slide hanger, the moving device is installed on the main machine for moving the glass slide hanger, the glass slide hanger is installed on the moving device through a mounting bracket, and is characterized in that: an air supply module is arranged on the mounting bracket, the air supply module is located above the glass slide hanger, and its air supply direction is aligned with the glass slide on the glass slide hanger.
[0005] Furthermore, the air supply module includes a fan and a motor, the fan is connected to the motor, the motor is installed on the mounting bracket through the fan base, and the motor is connected to the electric control mechanism.
[0006] Furthermore, the fan is a cross-flow fan, which is installed above the glass slide rack in a posture parallel to the glass slide rack, and the motor is installed on the fan seat on one side.
[0007] Furthermore, it also includes a drainage system and a liquid replenishment system, which are respectively connected to each liquid tank to form a waste liquid discharge structure and a reagent replenishment structure for the liquid tank.
[0008] Furthermore, the liquid discharge system includes a waste liquid bottle and a liquid outlet pump, each liquid tank is connected to a liquid outlet pump via an infusion tube, each liquid outlet pump is connected to the waste liquid bottle via a liquid outlet tube, and each liquid outlet pump adopts a peristaltic pump.
[0009] Furthermore, the fluid replenishment system includes a reagent bottle and a fluid inlet pump, each liquid tank is connected to a fluid inlet pump via an infusion tube, each fluid inlet pump is connected to the reagent bottle via the fluid inlet tube, and each fluid inlet pump adopts a peristaltic pump.
[0010] Preferably, there is one waste liquid bottle, and each liquid outlet pipe is connected to the same collecting pipe, which is connected to the waste liquid bottle.
[0011] Furthermore, the number of the reagent bottles is the same as the number of the liquid tanks, and each liquid inlet pump is connected to a reagent bottle via a liquid inlet pipe.
[0012] The utility model sets an air outlet module above the slide hanger. After the slide is lifted from the reagent after immersion, the air outlet module will open from the top of the slide to the liquid tank to blow away the residual reagent on the slide, which greatly reduces the concentration change caused by cross contamination of the reagents in each liquid tank due to the influence of the residual reagent, thereby improving the processing effect and efficiency of the sample. In addition, by setting up a drainage system and a liquid replenishment system, a certain frequency / time can be set according to the speed of purity decline, and the liquid outlet and liquid inlet pumps can be automatically started to discharge the reagent with reduced purity and add an equal amount of high-purity reagent to ensure the effect of sample processing. BRIEF DESCRIPTION OF THE DRAWINGS
[0013] Figure 1 This is the overall structure diagram of the utility model;
[0014] Figure 2 for Figure 1 A partial enlarged view of .
[0015] In the figure, 1 is the main unit, 2 is the liquid tank, 3 is the mobile device, 4 is the slide rack, 41 is the mounting bracket, 5 is the air supply module, 51 is the fan, 52 is the motor, 53 is the fan base, 6 is the reagent bottle, 61 is the liquid inlet pump, 62 is the liquid inlet pipe, 7 is the waste liquid bottle, 71 is the liquid outlet pump, 72 is the liquid outlet pipe, 73 is the collecting pipe, and 8 is the infusion pipe. DETAILED DESCRIPTION
[0016] In this embodiment, refer to Figure 1 and Figure 2The rapid slide staining machine with liquid blowing function includes a mainframe 1, an electric control mechanism, a plurality of liquid tanks 2 (for example, four), a moving device 3 and a slide hanger 4. The moving device 3 is installed on the mainframe 1 for moving the slide hanger 4. The slide hanger 4 is installed on the moving device 3 through a mounting bracket 41; an air supply module 5 is arranged on the mounting bracket 41, and the air supply module 5 is located above the slide hanger 4, and its air supply direction is aligned with the slide on the slide hanger 4. After the slide hanger 4 lifts the slide from the reagent (suspended above the corresponding liquid tank), the air supply module 5 is turned on to blow air to the slide, so as to blow the reagent remaining on the slide back to the original liquid tank 2 to avoid contaminating the reagents in other liquid tanks 2.
[0017] The air supply module 5 includes a fan 51 and a motor 52. The fan 51 is connected to the motor 52. The motor 52 is mounted on the mounting bracket 41 via a fan seat 53. The motor 52 is connected to an electric control mechanism and can work automatically and under control so as to automatically start the fan 51 to blow air.
[0018] The fan 51 is a cross-flow fan, which is installed above the glass slide rack 4 in a posture parallel to the glass slide rack 4, and the motor 52 is installed on a fan seat 53 on one side.
[0019] The apparatus also includes a drainage system and a liquid replenishment system, which are respectively connected to each liquid tank 2 to form a waste liquid discharge structure and a reagent replenishment structure for the liquid tank. The drainage system includes a waste liquid bottle 7 and a liquid outlet pump 71, each liquid tank 2 is connected to a liquid outlet pump 71 through an infusion tube 8, and each liquid outlet pump 71 is connected to the waste liquid bottle 7 through a liquid outlet tube 72, and each liquid outlet pump 71 adopts a peristaltic pump.
[0020] The liquid replenishment system includes a reagent bottle 6 and a liquid inlet pump 61. Each liquid tank 2 is connected to a liquid inlet pump 61 through an infusion tube 8. Each liquid inlet pump 61 is connected to the reagent bottle 6 through a liquid inlet tube 62. Each liquid inlet pump 61 adopts a peristaltic pump. The liquid inlet pump 61 and the liquid outlet pump 71 are both installed on the side of the host, and the reagent bottle 6 and the waste liquid bottle 7 are also located on the same side.
[0021] There is one waste liquid bottle 7 , and each liquid outlet pipe 72 is connected to the same collecting pipe 73 , which is then connected to the waste liquid bottle 7 through the collecting pipe 73 .
[0022] The number of the reagent bottles 6 is the same as the number of the liquid tanks 2, for example, four, and each liquid inlet pump 61 is connected to a reagent bottle 6 through a liquid inlet pipe 62. When the sample is immersed for a certain number of times, the purity will decrease due to the influence of the reagents remaining on the glass slide in different liquid tanks. At this time, according to the decreasing speed of the reagent purity, a certain frequency / time can be set to automatically start the liquid outlet pump 71 and the liquid inlet pump 61, discharge the reagent with reduced purity, and add an equal amount of high-purity reagent to ensure the effect of sample treatment.
[0023] The present invention has been described in detail above. The above description is only a preferred embodiment of the present invention and should not limit the scope of implementation of the present invention. That is, all equivalent changes and modifications made within the scope of this application should still fall within the scope of the present invention.
Claims
1. A rapid slide staining machine with liquid blowing function, comprising a main machine, an electric control mechanism, a plurality of liquid tanks, a moving device and a slide hanger, wherein the moving device is mounted on the main machine for moving the slide hanger, and the slide hanger is mounted on the moving device through a mounting bracket, characterized in that: An air supply module is arranged on the mounting bracket. The air supply module is located above the glass slide rack, and the air supply direction of the air supply module is aligned with the glass slide on the glass slide rack.
2. The rapid dyeing machine with liquid blowing function according to claim 1, characterized in that: The air supply module includes a fan and a motor. The fan is connected to the motor. The motor is installed on the mounting bracket through a fan seat. The motor is connected to the electric control mechanism.
3. The rapid dyeing machine with liquid blowing function according to claim 2, characterized in that: The fan is a cross-flow fan, which is installed above the glass slide rack in a posture parallel to the glass slide rack, and the motor is installed on the fan seat on one side.
4. The rapid dyeing machine with liquid blowing function according to claim 1, characterized in that: It also includes a liquid discharge system and a liquid replenishment system, which are respectively connected to each liquid tank to form a waste liquid discharge structure and a reagent replenishment structure for the liquid tank.
5. The rapid dyeing machine with liquid blowing function according to claim 4, characterized in that: The liquid discharge system comprises a waste liquid bottle and a liquid outlet pump. Each liquid tank is connected to a liquid outlet pump via an infusion tube. Each liquid outlet pump is connected to the waste liquid bottle via a liquid outlet tube. Each liquid outlet pump adopts a peristaltic pump.
6. The rapid dyeing machine with liquid blowing function according to claim 4, characterized in that: The liquid replenishment system includes a reagent bottle and a liquid inlet pump. Each liquid tank is connected to a liquid inlet pump through an infusion tube. Each liquid inlet pump is connected to the reagent bottle through the liquid inlet tube. Each liquid inlet pump adopts a peristaltic pump.
7. The rapid dyeing machine with liquid blowing function according to claim 5, characterized in that: There is one waste liquid bottle, and each liquid outlet pipe is connected to the same collecting pipe, which is connected to the waste liquid bottle.
8. The rapid dyeing machine with liquid blowing function according to claim 6, characterized in that: The number of the reagent bottles is the same as the number of the liquid tanks, and each liquid inlet pump is connected to a reagent bottle via a liquid inlet pipe.