Rapid sample collecting device of dissolution tester

Abstract

The utility model relates to a rapid sample collecting device of a dissolution tester, which comprises a dissolution tester body and a support table, the support table is positioned in front of the dissolution tester body, the top of the support table is fixedly connected with a mounting frame, the top of the mounting frame is fixedly connected with a blanking pipe, and the top of the blanking pipe is fixedly connected with a connecting block. A storage box is fixedly connected to the top of the connecting block, a blocking plate is slidably connected to the inner side of the connecting block, and a through hole is formed in the blocking plate. The motor is started to drive the crescent block to drive the cooperation block to rotate, the cooperation block can push the push plate to move so that the tension spring can slide, the through hole can be communicated with the bottom outlet of the storage box and the top inlet of the discharging pipe, one tablet can fall to the notch, meanwhile, the cooperation block drives the special-shaped block to rotate, and the tablets can fall from the notch. In this way, automatic discharging can be achieved, and manual operation is omitted.

Description

Technical Field

[0001] The utility model relates to a sample collecting device, in particular to a rapid sample collecting device for a dissolution instrument. Background Art

[0002] The absorption rate of drugs in the body is often determined by the speed of dissolution. Before being absorbed, drugs in solid preparations must undergo a process of disintegration and dissolution to become solutions. If the drug is not easily released from the preparation or the drug dissolves very slowly, there may be problems with the absorption rate or degree of the drug in the preparation. On the other hand, if some drugs with drastic pharmacological effects, small safety indexes, and rapid absorption dissolve too quickly, they may produce obvious adverse reactions and shorten the time to maintain the efficacy. In this case, the dissolution rate of the drug in the preparation should be controlled. Dissolution testing plays an important role in the quality consistency evaluation of drug preparations when they are imitated and changed after approval. The ultimate goal of drug dissolution testing is to reflect and control the in vivo dissolution and release behavior of drugs, and then reflect the in vivo absorption process of drugs, so as to ensure the safety and effectiveness of drugs. Conventional dissolution methods include basket method, paddle method, small cup method, etc. Dissolution instrument will be used for dissolution testing.

[0003] In the prior art, when a dissolution instrument is used to perform dissolution testing on tablets, a single tablet is generally manually placed into a beaker in the dissolution instrument. Depending on the model of the dissolution instrument, the tablet may be placed through a hole on the top of the dissolution instrument. Both methods require manual placement of the tablet, which is not convenient enough. Therefore, a rapid sample collection device for a dissolution instrument is proposed in the art to solve the above problem. Summary of the invention

[0004] In order to make up for the above shortcomings, the utility model provides a dissolution instrument sample rapid collection device, which aims to improve the problem that when the dissolution instrument in the prior art performs dissolution testing on tablets, a single tablet is generally manually put into the beaker in the dissolution instrument, depending on the model of the dissolution instrument, or the tablet is put into the dissolution instrument through the top hole, both of which require manual tablet placement, and the operation is not convenient enough.

[0005] To achieve the above-mentioned purpose, the utility model provides the following technical solutions: a rapid sample collection device for a dissolution instrument, comprising a dissolution instrument body and a support platform, the support platform is located in front of the dissolution instrument body, the top of the support platform is fixedly connected to a mounting frame, the top of the mounting frame is fixedly connected to a feeding pipe, the top of the feeding pipe is fixedly connected to a connecting block, the top of the connecting block is fixedly connected to a storage box, the inner side of the connecting block is slidably connected to a baffle plate, the interior of the baffle plate is provided with a through hole, the bottom of the baffle plate is fixedly connected to a tension spring, one end of the baffle plate is fixedly connected to a push plate, a motor is installed outside the mounting frame, the output end of the motor is fixedly connected to a crescent block, the outer side of the crescent block is fixedly connected to a coordination block, and a balanced feeding assembly is arranged outside the mounting frame, the balanced feeding assembly is used to evenly distribute and transport tablets for dissolution to each beaker.

[0006] Preferably, the above-mentioned balanced blanking assembly includes two special-shaped blocks, and the two special-shaped blocks are rotatably connected to the inner side and the outer side of the installation frame respectively.

[0007] Preferably, four notches are provided inside the above-mentioned special-shaped block, and the outer side of the external special-shaped block is slidably connected to the outer side of the crescent block.

[0008] Preferably, the outer side of the cooperation block is slidably connected to the notch, and the outer side of the cooperation block is slidably connected to one side of the push plate.

[0009] Preferably, an electric push rod is installed outside the above-mentioned installation frame, and the output end of the electric push rod is fixedly connected to a guide bucket.

[0010] Preferably, four delivery tubes are fixedly connected to the outside of the dissolution apparatus body, and a sampling detector is installed on the outside of the dissolution apparatus body.

[0011] Preferably, one end of the tension spring is fixedly connected to the outer side of the connecting block, and the top of the blocking plate is fixedly connected to the limiting block.

[0012] Preferably, the bottom outlet of the above-mentioned feeding pipe corresponds to the notch of the inner special-shaped block, and the bottom outlet of the guide bucket corresponds to the top inlet of the conveying pipe.

[0013] The utility model has the following beneficial effects:

[0014] 1. The utility model starts the motor to drive the crescent block to rotate the cooperative block, and the cooperative block pushes the push plate to move, so that the tension spring slides, so that the through hole is connected with the bottom outlet of the storage box and the top inlet of the feeding pipe, and a tablet falls into the notch. At the same time, the cooperative block drives the special-shaped block to rotate, and the tablet falls from the notch, so that automatic feeding can be realized, eliminating manual operation and reducing labor costs.

[0015] 2. In the utility model, the tablets discharged from the installation frame enter the guide bucket, and then slide along the internal channel of the conveying tube to the beaker at the bottom of the dissolution instrument body. Before the second tablet is discharged, the electric push rod is started to push the guide bucket to move, so that the outlet at the bottom of the guide bucket can be connected with the inlet of another conveying tube. In this way, tablets can be added to each beaker one by one. Finally, when the dissolution is completed, the solution is extracted by the sampling detector and added to the test tube inside the sampling detector, thereby improving efficiency. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] Figure 1 This is a three-dimensional diagram of the rapid sample collection device for a dissolution apparatus proposed by the utility model.

[0017] Figure 2 This is a schematic diagram of the storage box structure of the dissolution instrument sample rapid collection device proposed by the utility model.

[0018] Figure 3 This is a schematic diagram of the installation frame structure of the dissolution instrument sample rapid collection device proposed by the utility model.

[0019] Figure 4 This is a schematic diagram of the special-shaped block structure of the dissolution instrument sample rapid collection device proposed by the utility model.

[0020] In the figure, 1. dissolution instrument body; 2. support table; 3. installation frame; 4. feed pipe; 5. connection block; 6. storage box; 7. baffle plate; 8. through hole; 9. tension spring; 10. push plate; 11. motor; 12. crescent block; 13. coordination block; 14. special-shaped block; 15. electric push rod; 16. guide bucket; 17. conveying pipe; 18. sampling detector. DETAILED DESCRIPTION

[0021] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0022] like Figure 1-Figure 3As shown, an embodiment of the utility model is provided: a rapid sample collection device for a dissolution instrument, comprising a dissolution instrument body 1 and a support platform 2, the support platform 2 is located in front of the dissolution instrument body 1, a mounting frame 3 is fixedly connected to the top of the support platform 2, a feeding pipe 4 is fixedly connected to the top of the mounting frame 3, a connecting block 5 is fixedly connected to the top of the feeding pipe 4, a storage box 6 is fixedly connected to the top of the connecting block 5, a blocking plate 7 is slidably connected to the inner side of the connecting block 5, a through hole 8 is provided inside the blocking plate 7, a tension spring 9 is fixedly connected to the bottom of the blocking plate 7, a push plate 10 is fixedly connected to one end of the blocking plate 7, a motor 11 is installed outside the mounting frame 3, a crescent block 12 is fixedly connected to the output end of the motor 11, and the crescent block 1 2 is fixedly connected with a cooperation block 13, and a balanced feeding assembly is arranged on the outside of the mounting frame 3. The balanced feeding assembly is used to evenly distribute and convey the tablets for dissolution to each beaker. The starting motor 11 will drive the crescent block 12 to drive the cooperation block 13 to rotate, and the cooperation block 13 will push the push plate 10 to move, so that the tension spring 9 slides, so that the through hole 8 will be connected with the bottom outlet of the storage box 6 and the top inlet of the feeding tube 4, and a tablet will fall into the notch. At the same time, the cooperation block 13 drives the special-shaped block 14 to rotate, and the tablet will fall from the notch, and the tension spring 9 can quickly reset the baffle plate 7 to prevent multiple tablets from falling, and the limit block fits with the outside of the storage box 6 to ensure the stable position of the baffle plate 7.

[0023] like Figure 2-Figure 4 As shown, the above-mentioned balanced feeding assembly includes two special-shaped blocks 14, which are rotatably connected to the inner and outer sides of the installation frame 3 respectively, and four notches are opened inside the special-shaped blocks 14. The outer side of the external special-shaped block 14 is slidably connected to the outer side of the crescent block 12, the outer side of the cooperative block 13 is slidably connected to the notch, the outer side of the cooperative block 13 is slidably connected to one side of the push plate 10, an electric push rod 15 is installed on the outside of the installation frame 3, and a guide bucket 16 is fixedly connected to the output end of the electric push rod 15, four conveying pipes 17 are fixedly connected to the outside of the dissolution instrument body 1, and a sampling detector 18 is installed on the outside of the dissolution instrument body 1, one end of the tension spring 9 is fixedly connected to the outer side of the connecting block 5, and the blocking plate The top of the dissolution apparatus 1 is fixedly connected to the limiting block, the bottom outlet of the feeding tube 4 corresponds to the notch of the inner special-shaped block 14, and the bottom outlet of the guide bucket 16 corresponds to the top inlet of the conveying tube 17. The tablets discharged from the inside of the mounting frame 3 will enter the guide bucket 16, and then slide along the internal channel of the conveying tube 17 to the beaker at the bottom of the dissolution apparatus body 1. Before the second tablet is discharged, the electric push rod 15 is started to push the guide bucket 16 to move, so that the outlet at the bottom of the guide bucket 16 can be connected to the inlet of another conveying tube 17, so that tablets can be added to each beaker one by one, and finally the solution is extracted by the sampling detector 18 after the dissolution is completed, and then added to the test tube inside the sampling detector 18. The sampling detector 18 is an existing finished product equipment and is not described in detail.

[0024] The working principle of the utility model is as follows: first, the storage box 6 will store tablets inside, the starting motor 11 will drive the crescent block 12 to drive the cooperative block 13 to rotate, the cooperative block 13 will push the push plate 10 to move, so that the tension spring 9 will slide, so that the through hole 8 will be connected with the bottom outlet of the storage box 6 and the top inlet of the feeding tube 4, and the tablet will fall into the gap. At the same time, the cooperative block 13 will drive the special-shaped block 14 to rotate, and the tablet will fall from the gap, and the tension spring 9 can quickly reset the barrier plate 7 to prevent multiple tablets from falling, and the limit block is attached to the outside of the storage box 6. In addition, the tablets discharged from the inside of the mounting frame 3 will enter the guide bucket 16, and then slide along the internal channel of the conveying tube 17 to the beaker at the bottom of the dissolution instrument body 1. Before the second tablet is discharged, the electric push rod 15 is started to push the guide bucket 16 to move, so that the outlet at the bottom of the guide bucket 16 can be connected to the inlet of another conveying tube 17, so that the tablets can be added to each beaker one by one, and finally the solution is extracted by the sampling detector 18 after the dissolution is completed, and then added to the test tube inside the sampling detector 18.

Claims

1. A rapid sample collection device for a dissolution apparatus, comprising a dissolution apparatus body (1) and a support platform (2), characterized in that: The support platform (2) is located in front of the dissolution instrument body (1); the top of the support platform (2) is fixedly connected to a mounting frame (3); the top of the mounting frame (3) is fixedly connected to a feeding tube (4); the top of the feeding tube (4) is fixedly connected to a connecting block (5); the top of the connecting block (5) is fixedly connected to a storage box (6); the inner side of the connecting block (5) is slidably connected to a baffle plate (7); a through hole (8) is provided inside the baffle plate (7); a tension spring (9) is fixedly connected to the bottom of the baffle plate (7); one end of the baffle plate (7) is fixedly connected to a push plate (10); a motor (11) is installed outside the mounting frame (3); the output end of the motor (11) is fixedly connected to a crescent block (12); the outer side of the crescent block (12) is fixedly connected to a coordination block (13); and a balanced feeding assembly is arranged outside the mounting frame (3); the balanced feeding assembly is used to evenly distribute and transport tablets for dissolution to each beaker.

2. The rapid sample collection device for a dissolution apparatus according to claim 1, characterized in that: The balanced blanking assembly comprises two special-shaped blocks (14), and the two special-shaped blocks (14) are rotatably connected to the inner side and the outer side of the installation frame (3) respectively.

3. The rapid sample collection device for a dissolution apparatus according to claim 2, characterized in that: Four notches are provided inside the special-shaped block (14), and the outer side of the external special-shaped block (14) is slidably connected to the outer side of the crescent block (12).

4. The rapid sample collection device for a dissolution apparatus according to claim 3, characterized in that: The outer side of the cooperation block (13) is slidably connected to the notch, and the outer side of the cooperation block (13) is slidably connected to one side of the push plate (10).

5. The rapid sample collection device for a dissolution apparatus according to claim 1 or 2, characterized in that: An electric push rod (15) is installed outside the installation frame (3), and the output end of the electric push rod (15) is fixedly connected to a guide bucket (16).

6. The rapid sample collection device for a dissolution apparatus according to claim 1, characterized in that: Four delivery tubes (17) are fixedly connected to the outside of the dissolution instrument body (1), and a sampling detector (18) is installed on the outside of the dissolution instrument body (1).

7. The rapid sample collection device for a dissolution apparatus according to claim 1, characterized in that: One end of the tension spring (9) is fixedly connected to the outer side of the connecting block (5), and the top of the blocking plate (7) is fixedly connected to the limiting block.

8. The rapid sample collection device for a dissolution apparatus according to claim 2 or 3, characterized in that: The bottom outlet of the feed tube (4) corresponds to the notch of the inner special-shaped block (14).

9. The rapid sample collection device for a dissolution apparatus according to claim 5, characterized in that: The bottom outlet of the guide bucket (16) corresponds to the top inlet of the conveying pipe (17).

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