Double-layer coded disc and full-automatic fluorescence immunoassay analyzer comprising double-layer coded disc

Abstract

The utility model relates to a double-layer coded disc suitable for a full-automatic fluorescence immunoassay analyzer and the full-automatic fluorescence immunoassay analyzer comprising the double-layer coded disc, the double-layer coded disc comprises a coded disc I and a coded disc II, the coded disc I and the coded disc II are coaxially connected and arranged below an incubation disc, and a plurality of channels are arranged on the incubation disc; the code disc I and the code disc II are both provided with optocoupler detection grooves which are matched with optocouplers, and the optocouplers are used for identifying the optocoupler detection grooves, so that the channel position of the incubation disc is identified. According to the double-layer coded disc suitable for the full-automatic fluorescence immunoassay analyzer, the coded disc grooves are identified by utilizing the optocouplers, so that the number of channels in which the incubation discs above are positioned is identified, and the problem of accurate positioning of the rotation positions of the incubation discs of a plurality of channels is solved.

Description

Technical Field

[0001] The utility model belongs to the technical field of fluorescence immunoassay detection, and particularly relates to a double-layer code disk and a full-automatic fluorescence immunoassay analyzer containing the double-layer code disk. Background Art

[0002] Fluorescence immunoassay detection technology is a commonly used detection technology in current biomedical tests. This technology uses the characteristic that the analyte will produce fluorescence under the excitation of light with a specific wavelength to perform qualitative and quantitative detection on it. Due to a series of advantages such as high sensitivity, strong specificity, fast detection speed, safety and stability of the fluorescence immunoassay detection technology, it is widely used in clinical tests and has broad application prospects in detection fields such as endocrine disease detection, infectious disease detection, gynecological disease detection, tumor marker detection, genetic disease detection, blood and cytology detection. Traditional fluorescence immunoassay analyzers are usually large in volume and not convenient for handheld applications. Therefore, their development in emergency detection fields (such as emergency laboratories, ICUs, pediatrics, 120 ambulances, outdoor emergency rescue and first aid, individual first aid), areas with inconvenient transportation and underdeveloped economies is restricted. Even for some commercial products, there are also disadvantages such as single detection wavelength range, complex structure, poor reliability and low precision.

[0003] Since there are multiple channels on the incubation plate for placing reagent strips, it is easy to have problems with inaccurate positioning during rotation. Therefore, it is necessary to develop a new double-layer code disk applicable to a full-automatic fluorescence immunoassay analyzer and a full-automatic fluorescence immunoassay analyzer containing the double-layer code disk to solve the disadvantage of inaccurate positioning of the rotation position of the existing incubation plate. Summary of the Utility Model

[0004] The purpose of the utility model is to provide a double-layer code disk applicable to a full-automatic fluorescence immunoassay analyzer, which can solve the problem of precise positioning of the rotation position of the incubation plate with multiple channels.

[0005] To solve the above technical problems, the technical solution adopted by the utility model is that the double-layer code disk applicable to a full-automatic fluorescence immunoassay analyzer includes a first code disk and a second code disk. The first code disk and the second code disk are coaxially connected and are arranged below the incubation plate. Both the first code disk and the second code disk are provided with opto-coupler detection grooves, which are matched with the opto-coupler to identify the opto-coupler detection grooves by the opto-coupler, so as to identify the channel position of the incubation plate.

[0006] By adopting the above technical solution, a double-layer code disk, namely the first code disk and the second code disk, is added below the incubation plate. The opto-coupler is used to identify the code disk grooves, and then to identify which channel the upper incubation plate is in, so as to solve the problem of precise positioning of the rotation position of the incubation plate with multiple channels.

[0007] Preferably, the optocoupler includes Optocoupler 1 and Optocoupler 2. Optocoupler 1 is arranged on the first code disk, and Optocoupler 2 is arranged on the second code disk.

[0008] Preferably, a plurality of optocoupler detection grooves 1 are provided on the first code disk; optocoupler detection groove 2 is provided on the second code disk, and a reset point corresponding to optocoupler detection groove 2 is provided on Optocoupler 2.

[0009] Preferably, the incubation plate is provided with 24 channels and numbered according to the serial number. Optocoupler 1 is used to identify optocoupler detection groove 1, so as to identify the number of the channel where the incubation plate is located, that is, 24-channel positioning is realized.

[0010] Preferably, the number of optocoupler detection grooves 1 is the same as the number of channels on the incubation plate; the number of optocoupler detection grooves 2 is 1.

[0011] Preferably, both the first code disk and the second code disk are coaxially connected to the incubation plate.

[0012] Preferably, the first code disk and the second code disk have the same diameter, and a rotating gear is connected between the first code disk, the second code disk and the incubation plate; a reagent card incubation position is provided on the channel of the incubation plate.

[0013] Another problem to be solved by the present utility model is to provide a fully automatic fluorescence immunoassay analyzer with a double-layer code disk, so that the positioning of the reagent card detection disk is more accurate when rotating.

[0014] To solve the above technical problems, the technical solution adopted by the present utility model is: the fully automatic fluorescence immunoassay analyzer includes a bracket, the bracket is arranged on a base, and a sample inlet and outlet device, a reagent card magazine assembly, a diluent magazine assembly, a reagent card detection disk, a sampling needle movement assembly and a sample tube mixing assembly are arranged on the base. The sample inlet and outlet device is used to push a sample tube into the reagent card detection disk for detection and push the sample tube out for sample outlet; a sample tube mixing assembly, a diluent magazine assembly and a reagent card magazine assembly are arranged on the side of the sample inlet and outlet device. A plurality of reagent card cartridges are provided in the reagent card magazine assembly, and several reagent cards are stacked in the reagent card cartridges; the sample tube mixing assembly is used to mix the sample in the sample tube, wherein the sample tube is pushed into the sample inlet for detection and pushed out for sample outlet by the sample inlet and outlet device; the sampling needle movement assembly is used to extract the sample in the sample tube, a sampling needle is installed on the sampling needle movement assembly, and the sampling needle adds the sample diluted by the diluent magazine assembly to the sample adding port of the reagent card; an optical path detection assembly for detecting the reagent card and an emergency detection position are further arranged in the bracket, and the emergency detection position is arranged in the middle of the sample inlet and outlet device; the reagent card detection disk includes an incubation plate and a double-layer code disk, and the incubation plate and the double-layer code disk are coaxially connected.

[0015] Preferably, the double-layer code disk includes a first code disk and a second code disk. The first code disk and the second code disk are coaxially connected and arranged below the incubation disk. A plurality of channels are provided on the incubation disk. Optical coupling detection grooves are provided on both the first code disk and the second code disk and are matched with the optical couplers. The optical couplers are used to identify the optical coupling detection grooves, so as to identify the channel positions of the incubation disk.

[0016] Preferably, the optical couplers include a first optical coupler and a second optical coupler. The first optical coupler is arranged on the first code disk, and the second optical coupler is arranged on the second code disk. A plurality of first optical coupling detection grooves are provided on the first code disk. A second optical coupling detection groove is provided on the second code disk, and a reset point corresponding to the second optical coupling detection groove is provided on the second optical coupler.

[0017] The double-layer code disk applicable to the full-automatic fluorescence immunoassay analyzer of the present invention uses an optical coupler to identify the code disk groove, and then identifies which channel the upper incubation disk is in, so as to solve the problem of precise positioning of the rotation position of the incubation disk with multiple channels. Description of the Drawings

[0018] The following is a further detailed description in conjunction with the drawings and the embodiments of the present invention:

[0019] Figure 1 is a schematic structural diagram of the double-layer code disk of the present invention;

[0020] Figure 2 is a schematic structural diagram of the double-layer code disk of the present invention without the optical coupler Figure 1 ;

[0021] Figure 3 is a schematic structural diagram of the double-layer code disk of the present invention without the optical coupler Figure 2 ;

[0022] Figure 4 is a cross-sectional view of the double-layer code disk of the present invention;

[0023] Figure 5 is a bottom view of the double-layer code disk of the present invention;

[0024] Figure 6 is a top view of the double-layer code disk of the present invention;

[0025] Figure 7 is a structural diagram of the full-automatic fluorescence immunoassay analyzer of the present invention containing a double-layer code disk;

[0026] Figure 8 is a structural diagram of the full-automatic fluorescence immunoassay analyzer of the present invention containing a double-layer code disk without the base;

[0027] Wherein: 1 - First code disk; 2 - Second code disk; 3 - Incubation disk; 301 - Reagent card incubation position; 401 - First optocoupler detection groove; 402 - Second optocoupler detection groove; 501 - First optocoupler; 502 - Second optocoupler; 6 - Rotating gear; 7 - Bracket; 8 - Base; 9 - Sampling and discharging device; 10 - Reagent card detection disk; 11 - Sample tube mixing assembly; 12 - Optical path detection assembly; 13 - Sampling needle movement assembly; 1301 - Sampling needle; 14 - Reagent card bin assembly; 1401 - Reagent card magazine; 15 - Diluent bin assembly. Detailed implementation mode

[0028] The double-layer code disk applicable to a fully automatic fluorescence immunoassay analyzer of the present utility model is as Figures 1 to 6 shown. The double-layer code disk applicable to a fully automatic fluorescence immunoassay analyzer includes a first code disk 1 and a second code disk 2. The first code disk 1 and the second code disk 2 are coaxially connected and are arranged below the incubation disk 3. The first code disk 1 and the second code disk 2 are both provided with optocoupler detection grooves, which are matched with optocouplers. The optocouplers are used to identify the optocoupler detection grooves, so as to identify the channel positions of the incubation disk 3. The optocouplers include a first optocoupler 501 and a second optocoupler 502. The first optocoupler 501 is arranged on the first code disk 1, and the second optocoupler 502 is arranged on the second code disk 2. The first code disk 1 is provided with a plurality of first optocoupler detection grooves 401. The second code disk 2 is provided with a second optocoupler detection groove 402, and the second optocoupler 502 is provided with a reset point corresponding to the second optocoupler detection groove 402 for incubating disk reset. The incubation disk 3 is provided with 24 channels and is numbered according to the serial numbers. The first optocoupler 501 is used to identify the first optocoupler detection groove 401, so as to identify the number of the channel where the incubation disk 3 is located to realize channel positioning. The number of the first optocoupler detection grooves 401 on the first code disk 1 is the same as the number of channels on the incubation disk 3. The number of the second optocoupler detection grooves 402 on the second code disk 2 is 1. The diameters of the first code disk 1 and the second code disk 2 are the same. The first code disk 1 and the second code disk 2 are both coaxially connected to the incubation disk 3. And a rotating gear 6 is connected between the first code disk 1 and the second code disk 2 and the incubation disk 3. The channels of the incubation disk 3 are provided with reagent card incubation positions 301.

[0029] As Figures 7 to 8As shown in the figure, the fully automatic fluorescence immunoassay analyzer with a double-layer code disc includes a bracket 7, and the bracket 7 is arranged on a base 8. An injection and sampling device 9, a reagent card detection disc 10, a reagent card magazine assembly 14, a diluent magazine assembly 15, a sampling needle movement assembly 13, and a sample tube mixing assembly 11 are arranged on the base 8. The injection and sampling device 9 is used to push a sample tube into the reagent card detection disc 10 for detection and push the sample tube out for sampling. The sample tube mixing assembly 11, the diluent magazine assembly 15, and the reagent card magazine assembly 14 are arranged on the side of the injection and sampling device 9. A plurality of reagent card cartridges 1401 are provided in the reagent card magazine assembly 14, and a number of reagent cards are stacked in the reagent card cartridges 1401. The sample tube mixing assembly 11 is used to mix the sample in the sample tube. Herein, the sample tube is pushed into the injection port by the injection and sampling device 9 for detection and pushed out for sampling. The sampling needle movement assembly 13 is used to extract the sample in the sample tube. A sampling needle 1301 is installed on the sampling needle movement assembly 13, and the sampling needle 1301 adds the sample diluted by the diluent magazine assembly 15 to the sample addition port of the reagent card. An optical path detection assembly 12 for detecting the reagent card and an emergency detection position 16 are further arranged in the bracket 7. The emergency detection position 16 is arranged in the middle of the injection and sampling device 9. The reagent card detection disc 10 includes an incubation disc 3 and a double-layer code disc, and the incubation disc 3 and the double-layer code disc are coaxially connected. The double-layer code disc includes a code disc one 1 and a code disc two 2, and the code disc one 1 and the code disc two 2 are coaxially connected and arranged below the incubation disc 3. Optical coupler detection grooves are provided on both the code disc one 1 and the code disc two 2, which are matched with optical couplers. The optical couplers are used to identify the optical coupler detection grooves, so as to identify the channel position of the incubation disc 3. The optical couplers include an optical coupler one 501 and an optical coupler two 502. The optical coupler one 501 is arranged on the code disc one 1, and the optical coupler two 502 is arranged on the code disc two 2. A plurality of optical coupler detection grooves one 401 are provided on the code disc one 1. Optical coupler detection grooves two 402 are provided on the code disc two 2, and a reset point corresponding to the optical coupler detection grooves two 402 is provided on the optical coupler two 502 for incubating disc reset. 24 channels are provided on the incubation disc 3 and numbered in sequence. The optical coupler one 501 is used to identify the optical coupler detection grooves one 401, so as to identify the number of the channel where the incubation disc 3 is located to achieve channel positioning. The number of the optical coupler detection grooves one 401 on the code disc one 1 is the same as the number of channels on the incubation disc 3. The number of the optical coupler detection grooves two 402 on the code disc two 2 is 1. The diameters of the code disc one 1 and the code disc two 2 are the same. The code disc one 1 and the code disc two 2 are both coaxially connected to the incubation disc 3. And a rotating gear 6 is connected between the code disc one 1 and the code disc two 2 and the incubation disc 3. Reagent card incubation positions 301 are provided on the channels of the incubation disc 3.

[0030] The specific embodiments described above further elaborate on the purpose, technical solution, and beneficial effects of the present utility model. It should be understood that the above are only specific embodiments of the present utility model and are not used to limit the present utility model. Any modifications, equivalent replacements, improvements, etc., such as changes in the shape or material of a certain component, made within the spirit and principle of the present utility model shall be included within the protection scope of the present utility model.

Claims

1. A double-layer code disc, characterized in that: It includes a code disc 1 and a code disc 2, which are coaxially connected and arranged below an incubation disc, and a plurality of channels are arranged on the incubation disc; both the code disc 1 and the code disc 2 are provided with optical coupling detection grooves, which cooperate with the optical coupling, and utilize the optical coupling to identify the optical coupling detection grooves, thereby identifying the channel position of the incubation disc.

2. The double-layer code disc according to claim 1, characterized in that: The optical coupler includes an optical coupler 1 and an optical coupler 2. The optical coupler 1 is arranged on the code disk 1, and the optical coupler 2 is arranged on the code disk 2.

3. The double-layer code disc according to claim 2, characterized in that: The first code disc is provided with a plurality of first photocoupler detection grooves; the second code disc is provided with a second photocoupler detection groove and the second photocoupler is provided with a reset point corresponding to the second photocoupler detection groove.

4. The double-layer code disc according to claim 2, characterized in that: The incubation tray is provided with 24 channels and numbered in sequence. The optical coupler 1 is used to identify the optical coupler detection groove 1, thereby identifying the number of the channel where the incubation tray is located, thereby achieving 24-channel positioning.

5. The double-layer code disc according to claim 2, characterized in that: The number of the optical coupling detection grooves 1 is the same as the number of channels on the incubation plate; the number of the optical coupling detection grooves 2 is 1.

6. The double-layer code disc according to claim 5, characterized in that: The first code disc and the second code disc are both coaxially connected to the incubation disc.

7. The double-layer code disc according to claim 6, characterized in that: The diameters of the code disc 1 and the code disc 2 are the same, and rotating gears are connected between the code disc 1 and the code disc 2 and the incubation disc, and a reagent card incubation position is arranged on the channel of the incubation disc.

8. A fully automatic fluorescent immunoassay analyzer containing a double-layer code disk, characterized in that: The fully automatic fluorescent immunoassay analyzer comprises a bracket, which is arranged on a base, and a sample injection and sample output device, a reagent card storage assembly, a diluent storage assembly, a reagent card detection disk, a sampling needle movement assembly and a sample tube mixing assembly are arranged on the base, and the sample injection and sample output device is used to push the sample tube into the reagent card detection disk for detection and push the sample tube out for sample output; a sample tube mixing assembly, a diluent storage assembly and a reagent card storage assembly are arranged on the side of the sample injection and sample output device, and a plurality of reagent card clips are arranged in the reagent card storage assembly, and a plurality of reagent cards are stacked in the reagent card clips; the sample tube mixing assembly Used to mix the sample in the sample tube, wherein the sample tube is pushed in by the sample injection and sample output device for testing and pushed out for sample output; the sampling needle motion assembly is used to extract the sample in the sample tube, and the sampling needle is installed on the sampling needle motion assembly, and the sampling needle adds the sample diluted by the diluent tank assembly to the sample addition port of the reagent card; the bracket is also provided with an optical path detection assembly and an emergency detection position for detecting the reagent card, and the emergency detection position is arranged in the middle of the sample injection and sample output device; the reagent card detection disk includes an incubation disk and a double-layer code disk, and the incubation disk and the double-layer code disk are coaxially connected.

9. The fully automatic fluorescent immunoassay analyzer with a double-layer code disc according to claim 8, characterized in that: The double-layer code disc includes code disc one and code disc two, which are coaxially connected and arranged below an incubation disc, and a plurality of channels are arranged on the incubation disc; both code disc one and code disc two are provided with optical coupling detection grooves, which cooperate with optical couplings, and utilize optical couplings to identify the optical coupling detection grooves, thereby identifying the channel position of the incubation disc.

10. The fully automatic fluorescent immunoassay analyzer with a double-layer code disc according to claim 9, characterized in that: The optical coupler includes an optical coupler 1 and an optical coupler 2, wherein the optical coupler 1 is arranged on the code disk 1, and the optical coupler 2 is arranged on the code disk 2. The code disk 1 is provided with a plurality of optical coupler detection grooves 1; the code disk 2 is provided with an optical coupler detection groove 2 and the optical coupler 2 is also provided with a reset point corresponding to the optical coupler detection groove.

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