Solution detection device

Abstract

The utility model discloses a solution detection device, which relates to the technical field of liquid medicine detection devices and comprises a laser generation module, a control module and a control module, the photoelectric conversion module is used for receiving transmission light signals after the two paths of modulated laser respectively penetrate through the solution to be detected and the control sample solution, and converting the received two paths of transmission light signals into two paths of current signals; the signal processing module is used for converting the two paths of current signals into two paths of voltage signals and preprocessing the two paths of voltage signals to obtain differential signals; the demodulation filtering module is used for carrying out demodulation and low-pass filtering processing on the differential signal to obtain a data signal; and the upper computer is used for analyzing the data signal to obtain the composition and concentration of the solute of the solution to be detected.

Description

Technical Field

[0001] The utility model relates to the technical field of liquid medicine detection devices, in particular to a solution detection device. Background Art

[0002] Existing solution solute detection technology generally uses spectral analysis technology. Spectral analysis technology requires the spectrum of the solution to be tested to be detected and analyzed, and generally uses a spectrometer to achieve spectral detection. The spectrometer can be used to analyze the absorption spectrum of the drug to be tested, thereby determining the concentration and composition of the drug. The spectrometer has important value in the field of solution detection.

[0003] However, the purchase and maintenance costs of spectrometers are high, the cost-effectiveness is low, and the detection time of spectrometers is relatively long. At the same time, spectrometers require a large number of representative samples for analysis and modeling, which is obviously impractical for small batch sample detection. Therefore, the use of spectrometers to detect the solute components of solutions has problems such as high detection cost, high complexity, and low cost-effectiveness. Utility Model Content

[0004] In view of the defects in the prior art, the utility model provides a solution detection device to solve the problems of high cost, high complexity and low cost performance of traditional infusion solution detection.

[0005] A solution detection device comprises: a laser generating module, used for outputting two modulated lasers to irradiate a test solution and a control sample solution respectively; a photoelectric conversion module, used for receiving transmission light signals after the two modulated lasers pass through the test solution and the control sample solution respectively, and converting the received two transmission light signals into two current signals; a signal processing module, used for converting the two current signals into two voltage signals, and pre-processing the two voltage signals to obtain a differential signal; a demodulation and filtering module, used for demodulating and low-pass filtering the differential signal to obtain a data signal; and a host computer, used for analyzing the data signal to obtain the composition and concentration of the solute in the test solution.

[0006] Further, the laser generating module comprises a signal generator and a distributed feedback laser, and the signal generator is connected to a laser driver signal of the distributed feedback laser;

[0007] The signal generator provides a preset sawtooth wave scanning signal, and superimposes the modulation signal on the laser driver to drive the distributed feedback laser to output modulated laser.

[0008] Furthermore, the photoelectric conversion module is a semiconductor photodetector.

[0009] Furthermore, the semiconductor photodetector is a phototransistor.

[0010] Further, the signal processing module includes two signal processing branches and a differential amplification unit;

[0011] The input ends of the two signal processing branches are respectively connected to the photoelectric conversion module, and the output ends of the two signal processing branches are respectively connected to the in-phase input end and the inverting input end of the differential amplification unit; wherein,

[0012] The signal processing branch comprises a current-to-voltage unit and a voltage amplification unit which are connected in sequence, and an output end of the voltage amplification unit is connected to the differential amplification unit.

[0013] Furthermore, the model of the current-to-voltage unit is ADA4530.

[0014] Further, the model of the voltage amplification unit is OP07;

[0015] The output of the current-to-voltage unit is connected to the non-inverting input terminal of the voltage amplification unit.

[0016] Furthermore, the model of the differential amplifier unit is OP07.

[0017] Furthermore, the model of the demodulation and filtering module is STM32 single chip microcomputer.

[0018] Furthermore, the model of the host computer is a PC terminal.

[0019] The beneficial effects of the utility model are embodied in:

[0020] Compared with the traditional method, the solution detection device provided by the utility model uses a distributed feedback laser in the light source, broadens the spectral data, covers the detection of different characteristic peak bands of different liquids, improves the accuracy of liquid differentiation, and ensures the detection of the spectral characteristics of the transparent liquid to be tested in different bands.

[0021] In terms of detection technology, polarization imaging is used to simultaneously detect the concentrations and solute types of multiple liquids, meeting clinical medical needs; the final signal waveforms can be displayed, stored and processed by a PC terminal, making the utility model have the advantages of high detection accuracy, good timeliness, low detection cost and high cost performance. BRIEF DESCRIPTION OF THE DRAWINGS

[0022] In order to more clearly illustrate the specific implementation of the utility model or the technical solution in the prior art, the following is a brief introduction to the drawings required for the specific implementation or the prior art description. In all the drawings, similar elements or parts are generally identified by similar reference numerals. In the drawings, each element or part is not necessarily drawn according to the actual scale.

[0023] Figure 1An electrical structure block diagram of a solution detection device provided in an embodiment of the utility model;

[0024] Figure 2 A circuit diagram of a solution detection device provided by an embodiment of the utility model;

[0025] Figure 3 A circuit diagram of a current-to-voltage unit provided in an embodiment of the utility model;

[0026] Figure 4 A circuit diagram of a voltage amplification unit provided in an embodiment of the utility model;

[0027] Figure 5 A circuit diagram of a differential amplifier unit provided in an embodiment of the utility model;

[0028] Figure 6 The absorption degree reflected by the detection signal amplitude of glucose-biapenem at different concentrations and the signal detection amplitude of sodium chloride biapenem and glucose hydrochloride-ambroxol provided in the embodiments of the present invention. DETAILED DESCRIPTION

[0029] The following is a further detailed description of the implementation of the present invention in conjunction with the accompanying drawings and examples. The following examples are used to illustrate the present invention, but cannot be used to limit the scope of the present invention.

[0030] In the description of the present invention, unless otherwise specified, "multiple" means two or more; the terms "upper", "lower", "left", "right", "inner", "outer", "front end", "rear end", "head", "tail" and the like indicate the orientation or positional relationship based on the orientation or positional relationship shown in the drawings, which is only for the convenience of describing the present invention and simplifying the description, and does not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operate in a specific orientation, and therefore cannot be understood as limiting the present invention. In addition, the terms "first", "second", "third" and the like are only used for descriptive purposes and cannot be understood as indicating or implying relative importance.

[0031] In the description of the present invention, it should be noted that, unless otherwise clearly specified and limited, the terms "connected" and "connection" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0032] like Figure 1As shown, the utility model provides a solution detection device, including a laser generating module, a photoelectric conversion module, a signal processing module, a demodulation and filtering module and a host computer. Among them, the laser generating module is used to output two modulated lasers to irradiate the solution to be tested and the control sample solution respectively, and the laser emitted by the laser generating module is an infrared laser. The photoelectric conversion module is used to receive the transmitted light signals after the two modulated lasers pass through the solution to be tested and the control sample solution respectively, and convert the received two transmitted light signals into two current signals. The signal processing module is used to convert the two current signals into two voltage signals, and pre-process the two voltage signals to obtain a differential signal. The demodulation and filtering module is used to demodulate and low-pass filter the differential signal to obtain a data signal. The host computer is used to analyze the data signal to obtain the composition and concentration of the solute in the solution to be tested.

[0033] In this embodiment, Figure 2 As shown, the laser generating module includes a signal generator and a distributed feedback laser, and the signal generator is connected to the laser driver signal of the distributed feedback laser. The signal generator provides a preset sawtooth wave scanning signal, and superimposes the modulation signal on the laser driver to drive the distributed feedback laser to output modulated laser.

[0034] Specifically, the distributed feedback laser has the characteristics that the wavelength of the lasing light source is proportional to the injected driving current and can lasing a narrow-band frequency laser light source. By changing the driving current frequency, a low-frequency sawtooth wave is used to achieve current tuning, and a high-frequency sine wave is superimposed on the sawtooth wave for current modulation, thereby indirectly achieving the frequency sweep of the laser lasing wavelength and adjusting the frequency sweep range of the lasing wavelength so that it can completely cover the absorption peaks of the target solute and solvent.

[0035] After the target solute and solvent perform frequency-selective absorption of the laser light source, the residual light intensity is detected by the receiving end of the photoelectric conversion module, and the electrical signal is processed and demodulated using the signal processing module and the demodulation and filtering module. The demodulated odd harmonics or high harmonics are transmitted to the host computer for analysis, and the concentration and composition of the target liquid are finally obtained based on the Lambert-Beer law.

[0036] In this embodiment, the photoelectric conversion module is a semiconductor photodetector, and the semiconductor photodetector adopts a phototransistor.

[0037] In this embodiment, Figure 2As shown, the signal processing module includes two signal processing branches and a differential amplifier unit. The input ends of the two signal processing branches are respectively connected to the photoelectric conversion module, and the output ends of the two signal processing branches are respectively connected to the in-phase input end and the inverting input end of the differential amplifier unit. Among them, the signal processing branch includes a current-to-voltage unit and a voltage amplifier unit connected in sequence, and the output end of the voltage amplifier unit is connected to the differential amplifier unit.

[0038] In this embodiment, Figure 3 As shown, the model of the current-to-voltage unit is ADA4530. Figure 4 As shown, the model of the voltage amplifier unit is OP07, and the output of the current-to-voltage unit is connected to the in-phase input terminal of the voltage amplifier unit. The in-phase proportional operational amplifier circuit is formed by the OP07 chip to prevent the voltage signal from being too small to affect the processing of subsequent signals. The two voltage signals are passed through the corresponding voltage amplifier units to obtain two amplified voltage signals, which are input into the differential amplifier unit.

[0039] In this embodiment, Figure 5 As shown, the model of the differential amplifier unit is OP07. The differential amplifier circuit is composed of the OP07 chip, and the two amplified voltage signals are connected to the in-phase input terminal and the inverting input terminal of the differential amplifier unit OP07. The obtained differential signal is caused by the solute in the drug solution absorbing the incident monochromatic light, and the obtained differential signal is input to the demodulation filter module.

[0040] In this embodiment, the model of the demodulation and filtering module is an STM32 single-chip microcomputer, and the differential signal is demodulated and low-pass filtered in the STM32 single-chip microcomputer. During demodulation, the even harmonic component has a maximum value at the resonant position, and the value of each order harmonic component decreases successively; the demodulated signal is low-pass filtered to remove high-frequency clutter and obtain the final data signal.

[0041] In this embodiment, the host computer is a PC terminal. The PC terminal analyzes the final data signal to obtain the composition and concentration of the solute in the solution to be tested; the PC terminal displays various data measured by the system in real time as waveforms to measure the solute in the drug solution to be tested.

[0042] In summary, the working principle of the utility model is:

[0043] The signal generator outputs a sawtooth scanning signal, and superimposes the modulation signal of the fast sine frequency f on the laser driver to drive the distributed feedback laser. The distributed feedback laser provides the laser light source for the entire device and emits two infrared lasers.

[0044] The two infrared lasers are used to illuminate the test solution and the control sample solution respectively, and the semiconductor photodetector converts the two transmitted lights after passing through the test solution and the control sample solution respectively into two current signals. The operational amplifier ADA4530 is responsible for converting the two current signals into two voltage signals. The in-phase proportional operational amplifier circuit composed of the OP07 chip amplifies the two voltage signals converted by the ADA4530, and then the differential amplifier unit obtains the differential signal caused by the solute of the drug solution absorbing the incident monochromatic light, and finally the final data signal is obtained after being processed by the demodulation filter module.

[0045] The host computer analyzes the final data signal to obtain the composition and concentration of the solute in the solution to be tested. The host computer displays various data measured by the system in real time as waveforms to measure the solute in the drug solution to be tested.

[0046] Figure 6 The absorption degree reflected by the detection signal amplitude of glucose-biapenem at different concentrations and the signal detection amplitude of sodium chloride biapenem and glucose hydrochloride-ambroxol are shown. Figure 6 Middle: (a) and (b) show that the amplitude data obtained by different concentrations of biapenem in the same glucose solution are significantly different; (a) and (c) show that the amplitude trough of 0.1g / 100ml biapenem in sodium chloride solution is significantly lower than that in glucose; (a) and (d) show that the light absorption intensity increases proportionally with the increase of frequency. Biapenem shows a downward trend, while ambroxol hydrochloride shows an upward trend.

[0047] The products provided in the embodiments of the present invention are briefly described. For matters not mentioned in the embodiments, reference may be made to the corresponding contents in the aforementioned embodiments.

[0048] Finally, it should be noted that the above embodiments are only used to illustrate the technical solution of the utility model, rather than to limit it. Although the utility model has been described in detail with reference to the aforementioned embodiments, ordinary technicians in the field should understand that they can still modify the technical solutions recorded in the aforementioned embodiments, or replace some or all of the technical features therein with equivalents. These modifications or replacements do not make the essence of the corresponding technical solutions deviate from the scope of the technical solutions of the embodiments of the utility model, and they should all be included in the scope of the claims and description of the utility model.

Claims

1. A solution detection device, characterized in that: include: A laser generating module, used for outputting two modulated lasers to irradiate the test solution and the control sample solution respectively; A photoelectric conversion module is used to receive the transmitted light signals of the two modulated laser beams after they pass through the test solution and the control sample solution respectively, and convert the received two transmitted light signals into two current signals; A signal processing module, used for converting two current signals into two voltage signals, and preprocessing the two voltage signals to obtain a differential signal; A demodulation and filtering module, used to demodulate and low-pass filter the differential signal to obtain a data signal; and The host computer is used to analyze the data signal to obtain the composition and concentration of the solute in the solution to be tested.

2. A solution detection device as claimed in claim 1, characterized in that: The laser generating module comprises a signal generator and a distributed feedback laser, wherein the signal generator is connected to a laser driver signal of the distributed feedback laser; The signal generator provides a preset sawtooth wave scanning signal, and superimposes the modulation signal on the laser driver to drive the distributed feedback laser to output modulated laser.

3. A solution detection device as claimed in claim 1, characterized in that: The photoelectric conversion module is a semiconductor photodetector.

4. A solution detection device as claimed in claim 3, characterized in that: The semiconductor photodetector is a phototransistor.

5. A solution detection device as claimed in claim 1, characterized in that: The signal processing module includes two signal processing branches and a differential amplification unit; The input ends of the two signal processing branches are respectively connected to the photoelectric conversion module, and the output ends of the two signal processing branches are respectively connected to the in-phase input end and the inverting input end of the differential amplification unit; wherein, The signal processing branch comprises a current-to-voltage unit and a voltage amplification unit which are connected in sequence, and an output end of the voltage amplification unit is connected to the differential amplification unit.

6. A solution detection device as claimed in claim 5, characterized in that: The model of the current-to-voltage unit is ADA4530.

7. A solution detection device as claimed in claim 5, characterized in that: The model of the voltage amplification unit is OP07; The output of the current-to-voltage unit is connected to the non-inverting input terminal of the voltage amplification unit.

8. A solution detection device as claimed in claim 5, characterized in that: The model of the differential amplifier unit is OP07.

9. A solution detection device as claimed in claim 1, characterized in that: The model of the demodulation and filtering module is STM32 single chip microcomputer.

10. A solution detection device as claimed in claim 1, characterized in that: The model of the host computer is a PC terminal.

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