Regadenoson injection stirring device with nitrogen protection

Abstract

The utility model discloses a regadenoson injection stirring device with nitrogen protection, which comprises a stirring barrel, the stirring barrel is fixed on a base, an upper cover is hermetically arranged at an opening at the upper end of the stirring barrel through threads, the upper cover is provided with a motor, the output end of the motor is connected with a rotating shaft, and the rotating shaft is provided with a stirring rod in the stirring barrel. A rotating seat and an adjusting seat are arranged on the two sides of the stirring barrel respectively, the rotating seat is connected with a gas conveying pipe, the gas conveying pipe is connected with an external nitrogen pump, the adjusting seat is connected with a liquid conveying pipe and provided with a plugging block through a closed structure, a closed seat is arranged at the bottom of the stirring barrel and connected with a liquid outlet pipe, and a rubber valve is arranged at the position, located at the joint of the closed seat, of the liquid outlet pipe. A valve is arranged at the other end of the sealing seat. The regadenoson injection mixing device is simple in structure, regadenoson injection is rapidly mixed through the stirring mechanism, airflow is mixed in the solution by filling nitrogen into the regadenoson injection mixing device so as to accelerate the reaction speed, and the stirring mechanism is integrally closed, convenient to control, high in practicability and suitable for popularization.

Description

Technical Field

[0001] The utility model belongs to the technical field of stirring devices, and particularly relates to a stirring device for regadenoson injection with nitrogen protection. Background Art

[0002] Regadenoson injection is a stress drug used in radionuclide myocardial perfusion imaging, suitable for patients who cannot undergo exercise stress tests, such as the elderly, the frail, those with arthritis, peripheral vascular diseases, obesity, severe lung diseases, etc., who need to undergo drug stress tests to assist in the diagnosis of myocardial ischemia. Regadenoson injection can specifically activate related receptors in the coronary smooth muscle part, promote coronary artery dilation, and increase local blood flow, so it can be used as a stress drug for radionuclide myocardial perfusion imaging.

[0003] Due to the oxidation characteristics of regadenoson injection, during its production, the mixed solution cannot contact external air during stirring, resulting in a closed interior during stirring. And the stirring efficiency of the pure solution is lower than that of the stirring with mixed air, and it is also easy to contact air when discharging the stirred solution. Content of the Utility Model

[0004] The purpose of the utility model is to provide a stirring device for regadenoson injection with nitrogen protection, which has a simple structure. The regadenoson injection can be quickly mixed by the stirring mechanism, and nitrogen is filled inside to make the air flow mix in the solution to accelerate the reaction speed. The whole stirring mechanism is airtight, easy to control, highly practical, and suitable for popularization.

[0005] The utility model provides the following technical solution: a stirring device for regadenoson injection with nitrogen protection, including a stirring barrel, the stirring barrel is fixed on a base, the upper opening of the stirring barrel is hermetically provided with an upper cover through threads, a motor is fixedly installed at the center point of the upper cover, the output end of the motor is connected with a rotating shaft, the rotating shaft penetrates into the upper cover and is hermetically connected with it, and a plurality of stirring rods are fixedly arranged in an array on the rotating shaft inside the stirring barrel;

[0006] A rotating seat and an adjusting seat are respectively arranged on both sides of the stirring barrel. Both the rotating seat and the adjusting seat are hermetically connected with the stirring barrel through threaded pipes. The rotating seat is connected with an air delivery pipe, the air delivery pipe is connected with an external nitrogen pump, and a one-way valve is arranged at the connection of the air delivery pipe and the rotating seat;

[0007] The adjusting seat is connected with an infusion pipe, the infusion pipe is connected with an external pump body. A through sliding rail is arranged on the upper part of the adjusting seat, a sliding plate is slidably arranged in the sliding rail, the sliding plate penetrates through the sliding rail and fixedly provided with toggle blocks on both sides, and a blocking block is arranged inside the adjusting seat through an airtight structure where the sliding plate is located;

[0008] The bottom of the mixing barrel is provided with a sealed seat, the sealed seat is connected with a liquid outlet pipe, a rubber valve is arranged at the connection part of the liquid outlet pipe and the sealed seat, and the other end of the sealed seat is provided with a valve.

[0009] Preferably, a transparent observation window is arranged at the front end of the mixing barrel, a pressure display meter is fixedly arranged on the upper cover, and the pressure sensor of the pressure display meter is located below the upper cover.

[0010] Preferably, a connecting frame is fixedly arranged at the bottom of the sliding plate, the connecting frame is located in the adjusting seat, and is hermetically connected with the adjusting seat on the front and back sides. A convex strip is arranged on the side of the connecting frame facing the mixing barrel, the convex strip is inserted into the adjusting seat and is slidably connected with it. An internal groove is arranged on the other side of the connecting frame, and an insertion strip is arranged on the adjusting seat corresponding to the internal groove, the insertion strip is hermetically connected with the internal groove, and the convex strip is hermetically connected with the adjusting seat.

[0011] Preferably, a lower groove communicating with the threaded pipe is arranged at the bottom of the adjusting seat, a sealing block is fixedly arranged on the connecting frame at the position of the lower groove, the sealing block is hermetically connected with the threaded pipe on the side facing the threaded pipe, the lower groove is lower than the threaded pipe, and when the sealing block is opened, a U-shaped flow channel is formed.

[0012] The beneficial effects of the present utility model are as follows: the structure is simple, the injection solution of Regadenoson is quickly mixed by the mixing mechanism, and nitrogen is filled inside to make the air flow mix in the solution to accelerate the reaction speed. The mixing mechanism is integrally sealed, which is convenient to control and has strong practicability. Specifically as follows:

[0013] (1). The present utility model is provided with a mixing barrel, both sides of the mixing barrel are respectively connected with a liquid supply mechanism and a gas supply mechanism through threaded pipes, and the connection parts are sealed. The mixing barrel is an overall sealed cavity. When supplying liquid, nitrogen fills the mixing barrel, and the pump body supplies the Regadenoson mixed solution to the infusion pipe. When stirring the Regadenoson mixed solution, nitrogen exists in the mixing barrel, so that the stirred mixed solution is mixed with the gas, accelerating the stirring speed, and nitrogen does not react with the solution. After stirring is completed, the valve at the liquid outlet pipe is opened. At this time, under the action of pressure, the solution at the bottom squeezes open the rubber valve and is discharged from the liquid outlet pipe into a specified container. And before the infusion pipe supplies liquid to the mixing barrel, the gas pressure in the mixing barrel is observed through the pressure display meter. If the pressure is low, the gas supply pipe supplies gas to ensure the pressure in the mixing barrel.

[0014] (2) The utility model is provided with an adjustment seat. When the infusion tube is supplying liquid, the toggle blocks on both sides of the adjustment seat are pinched and pulled outward. At this time, the blocking block located in the adjustment seat moves outward and is drawn out from the threaded tube. At this time, a U-shaped flow channel is formed in the adjustment seat for liquid to pass through. The blocking block and the toggle block are connected by a connecting frame. When the connecting frame slides, it is always connected to the adjustment seat through the built-in groove and the convex strip, so that the adjustment seat remains airtight. After the liquid in the mixing barrel reaches a suitable height, the toggle block is released. Under the impact of the liquid, the blocking block moves forward and presses against the threaded tube to block it, thereby facilitating the control of liquid delivery. BRIEF DESCRIPTION OF THE DRAWINGS

[0015] The accompanying drawings are used to provide a further understanding of the present invention and constitute a part of the specification. Together with the embodiments of the present invention, they are used to explain the present invention and do not constitute a limitation of the present invention. In the accompanying drawings:

[0016] Figure 1 It is an overall schematic diagram of the utility model;

[0017] Figure 2 It is a cross-sectional view of the utility model;

[0018] Figure 3 It is an enlarged view of point A of the utility model;

[0019] Figure 4 It is an enlarged view of point B of the utility model;

[0020] The markings in the figure are: 1. mixing barrel; 2. base; 3. upper cover; 4. motor; 5. infusion tube; 6. rotating seat; 7. gas pipe; 8. pressure display gauge; 9. liquid outlet pipe; 10. observation window; 11. rotating shaft; 12. stirring rod; 13. closed seat; 14. one-way valve; 15. pressure sensor; 16. adjustment seat; 17. toggle block; 18. sliding rail; 19. sliding plate; 20. threaded pipe; 21. connecting frame; 22. sealing block; 23. lower groove; 24. built-in groove; 25. convex strip; 26. insertion strip; 27. rubber valve. DETAILED DESCRIPTION

[0021] The technical solutions in the embodiments of the utility model will be clearly and completely described below in conjunction with the drawings in the embodiments of the utility model; it is obvious that the described embodiments are only part of the embodiments of the utility model, rather than all of the embodiments, and all other embodiments obtained by ordinary technicians in this field based on the embodiments of the utility model without making creative work are within the scope of protection of the utility model.

[0022] In the description of the present utility model, it should be noted that the orientation or positional relationship indicated by terms such as "upper", "lower", "inner", "outer", "top / bottom end", etc. is based on the orientation or positional relationship shown in the drawings. It is only for the convenience of describing the present utility model and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation. Therefore, it should not be construed as a limitation to the present utility model.

[0023] In the description of the present utility model, it should be noted that unless otherwise clearly specified and defined, terms such as "installation", "provided with", "sheathed / connected", "connection", etc. should be understood in a broad sense. For example, "connection" can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be directly connected or indirectly connected through an intermediate medium, and it can be the communication inside two elements. For those of ordinary skill in the art, the specific meanings of the above terms in the present utility model can be understood according to specific circumstances.

[0024] Now, in combination with the accompanying drawings of the specification, the structural features of the present utility model will be described in detail.

[0025] See Figure 1-2 , a stirring device for ragagliflozin injection with nitrogen protection, including a stirring barrel 1, the stirring barrel 1 is fixed on a base 2, the upper opening of the stirring barrel 1 is hermetically provided with an upper cover 3 through threads to keep the opening airtight. A motor 4 is fixedly installed at the center point of the upper cover 3. The output end of the motor 4 is connected to a rotating shaft 11. The rotating shaft 11 penetrates into the upper cover 3 and is hermetically connected to it. A plurality of stirring rods 12 are fixedly arranged in an array on the rotating shaft 11 inside the stirring barrel 1. By driving the rotating shaft 11 to rotate through the motor 4, the stirring rods 12 stir the solution.

[0026] See Figure 2-4, on both sides of the mixing barrel 1, there are respectively a rotating seat 6 and an adjusting seat 16. The rotating seat 6 and the adjusting seat 16 are both hermetically connected to the mixing barrel 1 through a threaded pipe 20. The rotating seat 6 is connected with an air supply pipe 7, and the air supply pipe 7 is connected to an external nitrogen pump to supply nitrogen into the mixing barrel 1. A one-way valve 14 is provided at the connection between the air supply pipe 7 and the rotating seat 6. The adjusting seat 16 is connected with an infusion pipe 5, and the infusion pipe 5 is connected to an external pump body to supply the ragaglobin mixture into the mixing barrel 1. At the upper part of the adjusting seat 16, there is a through sliding rail 18. A sliding plate 19 is slidably arranged in the sliding rail 18. The sliding plate 19 penetrates through the sliding rail 18 and is fixedly provided with a toggling block 17 on both sides. By pinching the toggling block 17 to pull the sliding plate 19, the sliding plate 19 is located in the adjusting seat 16 through a sealing structure and is provided with a plugging block 22. The sliding plate 19 drives the plugging block 22 to translate. At the bottom of the mixing barrel 1, there is a sealing seat 13. The sealing seat 13 is connected with a liquid outlet pipe 9. The stirred solution is discharged from the liquid outlet pipe 9. A rubber valve 27 is provided at the connection between the liquid outlet pipe 9 and the sealing seat 13. The other end of the sealing seat 13 has a valve. When the valve is opened, under the action of pressure, the solution at the bottom squeezes open the rubber valve 27 and is discharged from the liquid outlet pipe 9.

[0027] See Figure 1-2 , a transparent observation window 10 is provided at the front end of the mixing barrel 1. A pressure display meter 8 is fixedly provided on the upper cover 3. The pressure sensor 15 of the pressure display meter 8 is located below the upper cover 3. The gas pressure in the mixing barrel 1 is observed through the pressure display meter 8. If the pressure is low, the air supply pipe 7 supplies gas.

[0028] See Figure 3-4 , a connecting frame 21 is fixedly provided at the bottom of the sliding plate 19. The connecting frame 21 is located in the adjusting seat 16 and is hermetically connected to the adjusting seat 16 on both the front and back sides. A convex strip 25 is provided on the side of the connecting frame 21 facing the mixing barrel 1. The convex strip 25 is inserted into the adjusting seat 16 and is slidably connected to it. An internal groove 24 is provided on the other side of the connecting frame 21. An inserting strip 26 is provided on the adjusting seat 16 corresponding to the internal groove 24. The inserting strip 26 is hermetically connected to the internal groove 24. The convex strip 25 is hermetically connected to the adjusting seat 16. When the connecting frame 21 slides, it is always connected to the adjusting seat 16 through the internal groove 24 and the convex strip 25, keeping the adjusting seat 16 airtight. At the bottom of the adjusting seat 16, there is a lower groove 23 communicating with the threaded pipe 20. A plugging block 22 is fixedly provided at the position where the connecting frame 21 is located in the lower groove 23. One side of the plugging block 22 facing the threaded pipe 20 is hermetically connected to it, blocking the threaded pipe 20. The lower groove 23 is lower than the threaded pipe 20. And when the plugging block 22 is opened, a U-shaped flow channel is formed, so that when the toggling block 17 is released, under the impact of the liquid, the plugging block 22 moves forward and abuts against the threaded pipe 20 to block it.

[0029] The utility model provides a nitrogen-protected reganoxan injection stirring device with a simple structure. The reganoxan injection is quickly mixed by the stirring mechanism, and nitrogen is added inside to mix the airflow in the solution to accelerate the reaction speed. The stirring mechanism is overall sealed, easy to control, highly practical, and suitable for promotion.

[0030] When using it specifically, refer to Figure 1-2 When supplying liquid, the stirring barrel 1 is filled with nitrogen, and the pump body supplies the Reganoxan mixed liquid to the infusion tube 5. When the Reganoxan mixed liquid is stirred, there is nitrogen in the stirring barrel 1, so that the stirred mixed liquid is mixed with the gas, which speeds up the stirring speed, and the nitrogen will not react with the solution. After the stirring is completed, the valve at the liquid outlet pipe 9 is opened. At this time, under the action of pressure, the solution at the bottom squeezes the rubber valve 27 and is discharged from the liquid outlet pipe 9 into the designated container. Before the infusion tube 5 supplies liquid to the stirring barrel 1, the gas pressure in the stirring barrel 1 is observed through the pressure display meter 8. If the pressure is low, the gas pipe 7 supplies gas to ensure the pressure in the stirring barrel 1.

[0031] Reference Figure 3-4 When the infusion tube 5 is supplying liquid, the toggle blocks 17 on both sides of the adjustment seat 16 are pinched and pulled outward. At this time, the blocking block 22 located in the adjustment seat 16 moves outward and is pulled out from the threaded tube 20. At this time, a U-shaped flow channel is formed in the adjustment seat 16 for liquid to pass through, and the blocking block 22 is connected to the toggle block 17 through the connecting frame 21. When the connecting frame 21 slides, it is always connected to the adjustment seat 16 through the built-in groove 24 and the convex strip 25, so that the adjustment seat 16 remains airtight. After the liquid in the mixing barrel 1 reaches a suitable height, the toggle block 17 is released. Under the impact of the liquid, the blocking block 22 moves forward and presses against the threaded tube 20 to block it, preventing the liquid from entering.

[0032] The above description is only a preferred embodiment of the utility model and is not intended to limit the utility model. Although the utility model is described in detail with reference to the above embodiments, those skilled in the art can still modify the technical solutions recorded in the above embodiments or replace some of the technical features therein by equivalents. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the utility model shall be included in the protection scope of the utility model.

Claims

1. A stirring device for a reganoxan injection with nitrogen protection, comprising a stirring barrel (1), wherein the stirring barrel (1) is fixed on a base (2), and an upper cover (3) is provided at the upper opening of the stirring barrel (1) through a threaded seal, characterized in that: A motor (4) is fixedly mounted at the center point of the upper cover (3); an output end of the motor (4) is connected to a rotating shaft (11); the rotating shaft (11) penetrates the upper cover (3) and is tightly connected thereto; the rotating shaft (11) is located in the mixing barrel (1) and is fixedly provided with a plurality of stirring rods (12) in an array; A rotating seat (6) and an adjusting seat (16) are respectively provided on both sides of the mixing barrel (1), and the rotating seat (6) and the adjusting seat (16) are both tightly connected to the mixing barrel (1) through a threaded pipe (20). The rotating seat (6) is connected to an air supply pipe (7), and the air supply pipe (7) is connected to an external nitrogen pump. A one-way valve (14) is provided at the connection between the air supply pipe (7) and the rotating seat (6); The adjustment seat (16) is connected to an infusion tube (5), and the infusion tube (5) is connected to an external pump body. A through sliding rail (18) is provided on the upper part of the adjustment seat (16), and a sliding plate (19) is slidably provided inside the sliding rail (18). The sliding plate (19) passes through the sliding rail (18) and is fixed with a toggle block (17) on both sides. The sliding plate (19) is located in the adjustment seat (16) through a closed structure and is provided with a blocking block (22); A sealed seat (13) is provided at the bottom of the mixing barrel (1), the sealed seat (13) is connected to a liquid outlet pipe (9), a rubber valve (27) is provided at the connection between the liquid outlet pipe (9) and the sealed seat (13), and a valve is provided at the other end of the sealed seat (13).

2. The stirring device for Reganoxan injection with nitrogen protection according to claim 1, characterized in that: A transparent observation window (10) is provided at the front end of the mixing barrel (1), a pressure display gauge (8) is fixedly provided at the upper cover (3), and a pressure sensor (15) of the pressure display gauge (8) is located below the upper cover (3).

3. The stirring device for injection of Reganoxan with nitrogen protection according to claim 1, characterized in that: A connecting frame (21) is fixedly provided at the bottom of the sliding plate (19), the connecting frame (21) is located in the adjusting seat (16), and the front and rear sides are tightly connected to the adjusting seat (16), the connecting frame (21) is provided with a convex strip (25) on the side facing the mixing barrel (1), the convex strip (25) is inserted into the adjusting seat (16) and is slidably connected thereto, the other side of the connecting frame (21) is provided with a built-in groove (24), the adjusting seat (16) is provided with an insertion strip (26) at a position corresponding to the built-in groove (24), the insertion strip (26) is tightly connected to the built-in groove (24), and the convex strip (25) is tightly connected to the adjusting seat (16).

4. The stirring device for injection of Reganoxan with nitrogen protection according to claim 3, characterized in that: The bottom of the adjustment seat (16) is provided with a lower groove (23) which is in communication with the threaded tube (20); the connection frame (21) is fixedly provided with a blocking block (22) at the lower groove (23); the blocking block (22) is hermetically connected to the threaded tube (20) on one side thereof; the lower groove (23) is lower than the threaded tube (20); and when the blocking block (22) is opened, a U-shaped flow channel is formed.

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