Liquid pumping device of DNA synthesizer convenient for discharging waste liquid

Abstract

The utility model is applicable to the technical field, and provides a liquid pumping device of a DNA (deoxyribonucleic acid) synthesizer convenient for discharging waste liquid, which comprises a synthesizer, a plurality of groups of liquid collecting holes are arranged at the top of the synthesizer, a synthesis cavity is arranged in an inner cavity of the synthesizer, a mounting box is arranged on one side of the synthesizer, and the synthesizer is fixedly communicated with the mounting box through an arranged water outlet pipe. The other side of the mounting box is fixedly communicated with a pressure pump by arranging a water inlet pipe, a filter plate and a sealing assembly used for keeping the filter plate and the mounting box stable and sealed are movably arranged in the mounting box, the water inlet pipe and the water outlet pipe are located on the two opposite sides of the mounting box, and the filter plate is arranged between the water inlet pipe and the water outlet pipe; according to the device, the cleaning assembly is arranged to be matched with the filter plate, so that the interior of the synthesis cavity is cleaned, the residual synthesis liquid is prevented from influencing the next liquid synthesis effect, waste liquid is immediately discharged and then filtered through the filter plate, a water source is made to meet other construction requirements, and water resource recycling is achieved.

Description

Technical Field

[0001] The utility model belongs to the technical field of biomedical equipment, and particularly relates to a liquid extraction device of a DNA synthesizer which is convenient for discharging waste liquid. Background Technique

[0002] The liquid extraction device of a DNA synthesizer is an important part of the DNA synthesizer. It is mainly used to extract the liquid in the reaction pool for the next step of processing or analysis. In the DNA synthesis experiment, the liquid extraction device is a very important part, which can greatly improve the accuracy and repeatability of the experiment.

[0003] When synthesizing DNA, a variety of reagents need to be injected into each hole of the porous synthesis plate according to specific chemical reaction steps. After injecting the reagents, the reagents flow along the hole wall to the carrier, so that the various reagents in each hole react in the carrier in turn to obtain a synthetic product. After the reaction of the various reagents is completed, the waste liquid after the reaction needs to be discharged.

[0004] After the existing DNA synthesizer finishes liquid extraction, when the waste liquid needs to be discharged, generally the device is manually tilted to make the waste liquid drain from the drain hole, but the waste liquid needs to be poured into a special bucket for treating waste liquid, which will waste the time and physical strength of the staff to treat the waste liquid, and it is also easy for the waste liquid to splash out, causing environmental pollution. Content of the Utility Model

[0005] The utility model provides a liquid extraction device of a DNA synthesizer which is convenient for discharging waste liquid, aiming to solve the problem that the DNA synthesizer is not convenient for treating waste liquid.

[0006] The utility model is realized as follows: a liquid extraction device of a DNA synthesizer which is convenient for discharging waste liquid, including a plurality of groups of liquid collection holes are opened at the top of the synthesizer, a synthesis cavity is arranged inside the synthesizer, one side of the synthesizer is provided with an installation box, and the synthesizer and the installation box are fixedly communicated through a water outlet pipe arranged, the other side of the installation box is fixedly communicated with a suction pump through a water inlet pipe, a filter plate and a sealing component for keeping the filter plate and the installation box in stable sealing are movably arranged inside the installation box, the water inlet pipe and the water outlet pipe are located on opposite sides of the installation box, and the filter plate is arranged between the water inlet pipe and the water outlet pipe, and cleaning components are arranged on both sides inside the synthesis cavity;

[0007] The installation box is provided with an installation groove, and a sliding groove is provided on the inner side wall of the installation box. The filter plate is slidably arranged in the sliding groove. The sealing component includes a sealing plate arranged at the installation groove, and the sealing plate is fixedly connected to the upper end side of the filter plate. A sunken groove communicating with the installation groove is provided on the top side of the installation box, and the peripheral side of the sealing plate is movably abutted against the inner peripheral side of the sunken groove; Sealing blocks are fixedly connected to the opposite inner side walls of the sliding groove, and sliding grooves are provided on one side of the two sliding grooves close to each other. The sliding grooves are arranged along the height direction of the sliding groove and penetrate through the sliding groove. The filter plate is slidably arranged in the sliding groove.

[0008] Preferably, the sealing component further includes a fixing member. The fixing member is set as a fixing block slidably arranged on the upper surface of the installation box. A fixing groove is provided on the side wall of the sunken groove of the installation box. The fixing groove is horizontally arranged and perpendicular to the sliding direction of the filter plate. The bottom side of the fixing block is movably abutted against the upper surface of the sealing plate.

[0009] Preferably, the fixing blocks are symmetrically arranged on both sides of the installation groove. The fixing blocks are arranged at intervals along the opening direction of the plurality of installation grooves, and several groups of fixing blocks are arranged at equal intervals.

[0010] Preferably, a fixing hole communicating with the fixing groove is provided on the upper surface of the installation box. The fixing block is movably connected in the fixing groove, and a spring is fixedly connected between the fixing block and the fixing groove. A connecting rod is commonly connected to several groups of the fixing blocks, and the connecting rod protrudes from the fixing block.

[0011] Preferably, a handle is fixedly connected to the upper surface of the sealing plate.

[0012] Preferably, the cleaning component includes brackets fixed to the inner top walls on both sides of the synthesis chamber. One end of each bracket is fixedly connected with a motor, and a spraying disc is fixedly connected to the output end of the motor. A plurality of nozzles are arranged at equal distances and communicated with the spraying disc.

[0013] Preferably, a water storage tank is fixedly arranged at the rear side of the synthesizer, and the water storage tank is connected with a water pump through a pipeline. The water outlet of the water pump is connected with two groups of water outlet pipes, and the other ends of the two groups of water outlet pipes are communicated with the spraying disc.

[0014] Compared with the prior art, the embodiments of the present application mainly have the following beneficial effects:

[0015] 1. By setting a cleaning component and a filter plate, the synthesis chamber can be cleaned to prevent the residual synthesis liquid from affecting the synthesis effect of the next liquid. The waste liquid is then discharged and filtered through the filter plate, so that the water source can meet other construction requirements, realize the recycling of water resources, and avoid wasting water resources. At the same time, a suction pump, an outlet pipe and an inlet pipe are set to facilitate the discharge and treatment of the waste liquid in the synthesizer. The staff does not need to pick up the synthesizer and wait for the waste liquid to be discharged, which saves the staff time to handle the waste liquid. It can also prevent the synthesizer liquid from splashing to the outside during treatment. By setting a cleaning component, after the liquid is pumped, cleaning liquid or water is added to the water storage tank, and the water in the water storage tank is discharged through the work of the water pump. The water or cleaning liquid is transported into the synthesis chamber, enters the spray disc through the water outlet pipe, and finally sprayed out through multiple nozzles to achieve rapid cleaning of the inner wall of the synthesis chamber; and the controller sends a signal to the motor, so that the motor can drive the spray disc to deflect at a certain angle, expand the spraying range, and further all-round cleaning. After the cleaning is completed, the suction pump works to extract the waste water in the synthesis chamber, so that the waste water in the synthesis chamber enters the installation box through the water outlet pipe. Under the filtering effect of the filter plate, the waste water makes the water source meet other construction requirements, realizes the recycling of water resources, and avoids the waste of water resources. At the same time, it is easy to disassemble and clean the filter plate to prevent the filter plate from being used for a long time and causing blockage to affect subsequent filtration;

[0016] 2. By toggling the connecting rod, the connecting rod pulls the fixed block to slide away from the sealing plate, so that the fixed block moves into the fixed groove until the fixed block is completely moved into the fixed groove, thereby realizing the restriction of the sealing plate by the fixed block, and the filter plate can be pulled out of the sliding groove, and the filter plate can be cleaned. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] Figure 1 It is an overall stereogram of the utility model;

[0018] Figure 2 It is the overall front view of the utility model;

[0019] Figure 3 It is a side cutaway view of the entirety of the utility model;

[0020] Figure 4 The utility model Figure 3 Schematic diagram of the structure enlarged at point A in the middle.

[0021] In the figure: 1. synthesizer; 2. suction pump; 3. sealing assembly; 31. sealing block; 32. sliding groove; 33. sealing plate; 34. tightening pad; 35. fixing block; 36. handle; 37. fixing groove; 38. fixing hole; 39. connecting rod; 4. installation box; 5. filter plate; 6. water pump; 7. water outlet pipe; 8. water storage tank; 9. bracket; 10. motor; 11. spray disc; 12. nozzle. Specific embodiments

[0022] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this application belongs; the terms used in the specification of this application are only for the purpose of describing specific embodiments and are not intended to limit this application; the terms "including" and "having" and any variations thereof in the specification and claims of this application and the above drawings are intended to cover non-exclusive inclusion. The terms "first", "second", etc. in the specification and claims of this application or the above drawings are used to distinguish different objects and not to describe a specific order.

[0023] Reference to "embodiments" herein means that a particular feature, structure, or characteristic described in connection with the embodiments can be included in at least one embodiment of this application. The phrase appears in various places in the specification and does not necessarily refer to the same embodiment, nor is it an independent or alternative embodiment mutually exclusive with other embodiments. It is explicitly and implicitly understood by those skilled in the art that the embodiments described herein can be combined with other embodiments.

[0024] An embodiment of the present utility model provides a liquid extraction device for a DNA synthesizer that facilitates the discharge of waste liquid, as Figures 1-4 shown, a plurality of liquid collection holes are opened at the top of the synthesizer 1, a synthesis chamber is provided inside the synthesizer 1, an installation box 4 is arranged on one side of the synthesizer 1, and the synthesizer 1 and the installation box 4 are fixedly connected through a water outlet pipe arranged therebetween. The other side of the installation box 4 is fixedly connected with a suction and pressure pump 2 through a water inlet pipe. A filter plate 5 and a sealing assembly 3 for keeping the filter plate 5 and the installation box 4 stably sealed are movably arranged in the installation box 4. The water inlet pipe and the water outlet pipe are located on opposite sides of the installation box 4, and the filter plate 5 is arranged between the water inlet pipe and the water outlet pipe. Cleaning components are arranged on both sides inside the synthesis chamber;

[0025] An installation groove is opened on the installation box 4, and a sliding groove 32 is opened on the inner side wall of the installation box 4. The filter plate 5 is slidably arranged in the sliding groove 32. The sealing assembly 3 includes a sealing plate 33 arranged at the installation groove. The sealing plate 33 is fixedly connected to the upper end side of the filter plate 5. A sunken groove communicated with the installation groove is opened on the top side of the installation box 4. The periphery of the sealing plate 33 is movably abutted against the inner periphery of the sunken groove; Sealing blocks 31 are fixedly connected to the opposite inner side walls of the sliding groove 32. A sliding groove 32 is opened on one side of each of the two sliding grooves 32 close to each other. The sliding groove 32 is arranged along the height direction of the sliding groove 32. The sliding groove 32 penetrates through the sliding groove 32. The filter plate 5 is slidably arranged in the sliding groove 32.

[0026] It should be noted that after the existing DNA synthesizer finishes pumping liquid, when the waste liquid needs to be discharged, generally the device is manually tilted to let the waste liquid drain from the drain hole. However, the waste liquid needs to be poured into a special bucket for treating waste liquid, which will waste the time and physical strength of the staff in treating the waste liquid, and it is also easy for the waste liquid to splash out, causing environmental pollution. Therefore, in order to solve the problem that the existing DNA synthesizer is not convenient for treating waste liquid, this solution realizes the cleaning of the synthesis cavity by setting a cleaning component in cooperation with the filter plate 5, avoiding the influence of the residual synthesis liquid on the synthesis effect of the next liquid. Then, after the waste liquid is discharged, it is filtered through the filter plate 5 to make the water source meet other construction requirements, realizing the recycling of water resources and avoiding waste of water resources. At the same time, a suction and pressure pump 2, a water outlet pipe and a water inlet pipe are set up to facilitate the discharge and treatment of the waste liquid in the synthesizer.

[0027] Specifically, in this embodiment, this solution mainly realizes the cleaning of the synthesis cavity by setting a cleaning component in cooperation with the filter plate 5, avoiding the influence of the residual synthesis liquid on the synthesis effect of the next liquid. Then, after the waste liquid is discharged, it is filtered through the filter plate 5 to make the water source meet other construction requirements, realizing the recycling of water resources and avoiding waste of water resources. At the same time, a suction and pressure pump 2, a water outlet pipe and a water inlet pipe are set up to facilitate the function of discharging and treating the waste liquid in the synthesizer. By setting the cleaning component, after the liquid pumping is completed, cleaning liquid or water is added to the water storage tank 8. Through the operation of the water pump 6, the water or cleaning liquid in the water storage tank 8 is transported into the synthesis cavity, enters the spray disc 11 through the water outlet pipe 7, and finally sprays out through a plurality of nozzles 12 to realize the rapid cleaning of the inner wall of the synthesis cavity; and the controller sends a signal to the motor 10, enabling the motor 10 to drive the spray disc 11 to deflect at a certain angle, expanding the spraying range and further cleaning comprehensively. After the cleaning is completed, then the suction and pressure pump 2 works. When extracting the waste water in the synthesis cavity, the waste water in the synthesis cavity enters the installation box 4 through the water outlet pipe. Under the filtering action of the filter plate 5, the water source meets other construction requirements, realizing the recycling of water resources and avoiding waste of water resources. At the same time, it is also convenient to disassemble and clean the filter plate 5 to prevent the filter plate 5 from being blocked after long-term use, affecting subsequent filtration.

[0028] In a further preferred embodiment of the present utility model, as Figures 2-4 shown, the sealing component 3 further includes a fixing member, and the fixing member is set to be slidably arranged on the fixing block 35 on the upper surface of the installation box 4. A fixing groove 37 is opened on the side wall of the installation box 4 in the sunken groove. The fixing groove 37 is horizontally arranged and perpendicular to the sliding direction of the filter plate 5. The bottom side of the fixing block 35 is movably abutted against the upper surface of the sealing plate 33.

[0029] In this embodiment, under the filtering action of the filter plate 5, the water source meets other construction requirements, realizing the recycling of water resources and avoiding waste of water resources.

[0030] In a further preferred embodiment of the present utility model, as Figures 1-4 shown, the fixing blocks 35 are symmetrically arranged on both sides of the installation groove, the fixing blocks 35 are arranged at intervals along the opening direction of a plurality of installation grooves, and several groups of fixing blocks 35 are arranged at equal intervals.

[0031] In this embodiment, by arranging the fixing blocks 35, sliding the fixing blocks 35 to make the fixing blocks 35 abut against the sealing plate 33, so that the abutting pads 34 on the bottom side of the sealing plate 33 abut against the upper surface of the sinking groove, realizing the sealing of the installation box 4.

[0032] In a further preferred embodiment of the present utility model, as Figures 2-4 shown, a handle 36 is fixedly connected to the upper surface of the sealing plate 33.

[0033] In this embodiment, by arranging the handle 36, it is convenient for the user to extract the filter plate 5, so as to install and disassemble the filter plate 5.

[0034] In a further preferred embodiment of the present utility model, as Figures 2-4 shown, the cleaning assembly includes brackets 9 fixed to the inner top walls on both sides of the synthesis cavity, one end of the brackets 9 is fixedly connected with a motor 10, the output end of the motor 10 is fixedly connected with a spray disc 11, and a plurality of nozzles 12 are communicated and arranged on the spray disc 11 at equal distances.

[0035] In this embodiment, the controller sends a signal to the motor 10, so that the motor 10 can drive the spray disc 11 to deflect at a certain angle, expanding the spraying range and further cleaning in all directions.

[0036] It should be noted that for the foregoing embodiments, for the sake of simple description, they are all expressed as a series of action combinations. However, those skilled in the art should know that the present utility model is not limited by the described action sequence, because according to the present utility model, certain steps may be adopted in other sequences or simultaneously. Secondly, those skilled in the art should also know that the embodiments described in the specification are all preferred embodiments, and the actions and modules involved are not necessarily essential to the present utility model.

[0037] In several embodiments provided by the present application, it should be understood that the disclosed device can be implemented in other ways. For example, the device embodiments described above are only illustrative. For example, the above-mentioned unit division can be implemented in other ways in actual implementation. For example, multiple units or components can be combined or integrated into another system, or some features can be ignored or not executed. Another point, the shown or discussed coupling or communication connection between each other can be through some interfaces, and the indirect coupling or communication connection between devices or units can be in the form of telecommunications or other forms.

[0038] The units described above as separate components may or may not be physically separated, and the components shown as units may or may not be physical units, that is, they may be located in one place or distributed over multiple network units. Some or all of the units can be selected according to actual needs to achieve the purpose of the solution of this embodiment.

[0039] The above embodiments are only used to illustrate the technical solutions of the present invention, rather than limiting the protection scope of the present invention. Obviously, the described embodiments are only some embodiments of the present invention, rather than all embodiments. Based on these embodiments, all other embodiments obtained by those of ordinary skill in the art without creative efforts belong to the scope of protection of the present invention. Although the present invention has been described in detail with reference to the above embodiments, those of ordinary skill in the art can still, without conflict and without creative efforts, combine, add or delete the features in the embodiments of the present invention according to the situation, or make other adjustments, so as to obtain different technical solutions that essentially do not deviate from the concept of the present invention, and these technical solutions also belong to the scope of protection of the present invention.

Claims

1. A liquid extraction device for a DNA synthesizer that facilitates the discharge of waste liquid, characterized in that: The synthesizer (1) comprises a plurality of groups of liquid collecting holes formed on the top thereof, a synthesis chamber being formed in the inner cavity of the synthesizer (1), a mounting box (4) being provided on one side of the synthesizer (1), and the synthesizer (1) and the mounting box (4) being fixedly connected via a water outlet pipe, a suction pump (2) being fixedly connected via a water inlet pipe on the other side of the mounting box (4), a filter plate (5) and a sealing assembly (3) for maintaining a stable seal between the filter plate (5) and the mounting box (4) being movably provided in the mounting box (4), the water inlet pipe and the water outlet pipe being located on opposite sides of the mounting box (4), and the filter plate (5) being provided between the water inlet pipe and the water outlet pipe, and cleaning assemblies being provided on both sides of the interior of the synthesis chamber; The installation box (4) is provided with an installation groove, and the inner wall of the installation box (4) is provided with a sliding groove (32), the filter plate (5) is slidably arranged in the sliding groove (32), the sealing assembly (3) comprises a sealing plate (33) arranged at the installation groove, the sealing plate (33) is fixedly connected to the upper end side of the filter plate (5), the top side of the installation box (4) is provided with a sink groove connected to the installation groove, the peripheral side of the sealing plate (33) is movably pressed against the inner peripheral side of the sink groove; sealing blocks (31) are fixedly connected to the two opposite inner walls of the sliding groove (32), the sliding groove (32) is provided on the side close to each other of the two sliding grooves (32), the sliding groove (32) is arranged along the height direction of the sliding groove (32), the sliding groove (32) penetrates the sliding groove (32), and the filter plate (5) is slidably arranged in the sliding groove (32).

2. A liquid extraction device for a DNA synthesizer for facilitating the discharge of waste liquid as claimed in claim 1, characterized in that: The sealing assembly (3) further comprises a fixing member, which is arranged to be a fixing block (35) slidably arranged on the upper surface of the installation box (4), and the installation box (4) is provided with a fixing groove (37) on the side wall of the sink, and the fixing groove (37) is arranged horizontally and perpendicular to the sliding direction of the filter plate (5), and the bottom side of the fixing block (35) is movably pressed against the upper surface of the sealing plate (33).

3. A liquid extraction device for a DNA synthesizer for facilitating the discharge of waste liquid as claimed in claim 2, characterized in that: The fixing blocks (35) are symmetrically arranged on both sides of the installation slots. The fixing blocks (35) are arranged at intervals along the direction in which the plurality of installation slots are opened, and a plurality of groups of the fixing blocks (35) are arranged at equal intervals.

4. A liquid extraction device for a DNA synthesizer for facilitating the discharge of waste liquid as claimed in claim 3, characterized in that: The upper surface of the installation box (4) is provided with a fixing hole (38) which is connected to the fixing groove (37); the fixing block (35) is movably connected in the fixing groove (37); a spring is fixedly connected between the fixing block (35) and the fixing groove (37); and a connecting rod (39) is commonly connected to a plurality of groups of the fixing blocks (35); the connecting rod (39) is arranged to protrude from the fixing block (35).

5. A liquid extraction device for a DNA synthesizer for facilitating the discharge of waste liquid as claimed in claim 3, characterized in that: A handle (36) is fixedly connected to the upper surface of the sealing plate (33).

6. A liquid extraction device for a DNA synthesizer for facilitating the discharge of waste liquid as claimed in claim 4, characterized in that: The cleaning component comprises a bracket (9) fixed to the inner top walls on both sides of the synthesis chamber, one end of the bracket (9) is fixedly connected to a motor (10), the output end of the motor (10) is fixedly connected to a spray disc (11), and the spray disc (11) is connected to and provided with a plurality of nozzles (12) distributed at equal distances.

7. A liquid extraction device for a DNA synthesizer for facilitating the discharge of waste liquid as claimed in claim 1, characterized in that: A water storage tank (8) is fixedly arranged on the rear side of the synthesizer (1), and the water storage tank (8) is connected to a water pump (6) via a pipeline, and the water outlet of the water pump (6) is connected to two groups of water outlet pipes (7), and the other ends of the two groups of water outlet pipes (7) are connected to the spray plate (11).

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