Liquid cover film independent temperature control dynamic mixing device

Abstract

The utility model discloses a liquid cover film independent temperature control dynamic mixing device, which comprises a fixing frame and heating sheets arranged on the upper surface of the fixing frame at equal intervals, sample slides are arranged on the upper surfaces of the heating sheets, liquid cover films are arranged on the upper surfaces of the sample slides, two ends of the fixing frame are connected with push-pull plates in a sliding manner through slide ways, and the push-pull plates are connected with the liquid cover films through slide ways. The upper surface of the push-pull plate is detachably connected with the rear end of the liquid cover film through a formed groove. The sample slide is placed on the upper surface of the heating plate, then a reagent is added to the upper surface of the heating plate, then the liquid cover film covers the sample slide, and the push-pull plate and the liquid cover film are driven by the driving assembly to move back and forth, so that the sample slide is conveniently and independently heated, the sample is fully mixed, and the reagent is fully reacted; the staining quality is improved, the cost is saved, and as the liquid cover film covers the slide, when the sample slide is incubated at high temperature, the volatilization of a reagent is prevented, and the waste of the reagent is reduced.

Description

Technical Field

[0001] The utility model relates to the technical field of reagent mixing, in particular to a liquid cover film independent temperature control dynamic mixing device. Background Technique

[0002] The liquid cover film is a kind of liquid protective film, which is applied to the staining system. For the common slide specimen treatment, the slides are laid flat or slightly inclined one by one and placed in an open container for unified heating. However, in such a treatment method, the temperature fluctuation range is large, and the temperature at different positions in the container will deviate. It is difficult to accurately control the temperature, resulting in the treatment of some specimens not reaching the predetermined temperature, thereby reducing the accuracy of the slide detection results.

[0003] During the staining process, since only a small amount of reagent needs to be added for the mixing action to ensure sufficient reaction of the reagent, but when manually mixing the reagent, the efficiency of mixing the reagent is low. Therefore, further optimization is made for the above problems. Content of the Utility Model

[0004] In view of the deficiencies of the prior art, the utility model provides a liquid cover film independent temperature control dynamic mixing device, which solves the problems put forward in the above background technique.

[0005] To achieve the above purpose, the utility model is realized through the following technical solutions: A liquid cover film independent temperature control dynamic mixing device includes a fixed frame and heating sheets equidistantly arranged on the upper surface of the fixed frame. A sample slide is arranged on the upper surface of the heating sheet, and a liquid cover film is arranged on the upper surface of the sample slide. Both ends of the fixed frame are slidably connected with a push-pull plate through slideways, and the rear end of the liquid cover film is detachably connected to the upper surface of the push-pull plate through a groove opened thereon;

[0006] The lower surface of the fixed frame is fixedly connected with a driving component and is used to drive the push-pull plate to move back and forth, so as to mix the reagent on the surface of the sample slide. The rear end of the push-pull plate is movably connected with a pressing plate through a pin shaft and is used in cooperation with the liquid cover film. The rear end of the push-pull plate is fixedly connected with a reagent kit through a U-shaped plate.

[0007] The utility model has the following beneficial effects:

[0008] In this liquid cover film independent temperature control dynamic mixing device, the sample slide is placed on the upper surface of the heating sheet, then the reagent is added on its upper surface, and then the liquid cover film is covered above the sample slide. The driving component drives the push-pull plate and the liquid cover film to move back and forth, which is convenient for independently heating the sample slide. That is, it realizes sufficient mixing of the sample, ensures sufficient reaction of the reagent, improves the staining quality, and saves costs. Since the liquid cover film is covered above the slide, when the sample slide is incubated at a high temperature, it prevents the volatilization of the reagent and reduces the waste of the reagent;

[0009] The liquid cover film independent temperature control dynamic mixing device, when the driving component drives the push-pull plate to move back and forth, test tubes can be pre-placed inside the reagent kit, facilitating the preliminary mixing of the reagents inside, reducing the steps of manual mixing, and using the pressing plate to press the liquid cover film to prevent loosening during the back-and-forth movement;

[0010] The liquid cover film independent temperature control dynamic mixing device, when the gear cylinder is meshed and connected with the threaded rod, drives the reciprocating screw rod to rotate through the driving block, and can drive the threaded rod to rotate synchronously, so that the placing plate extends out from both sides of the fixing frame, facilitating the placement of the instruments to be used and convenient for taking. Description of the Drawings

[0011] Figure 1 is a schematic exploded view of the liquid cover film and the heating sheet of the present utility model;

[0012] Figure 2 is a three-dimensional structural schematic diagram of the fixing frame of the present utility model;

[0013] Figure 3 is a three-dimensional structural schematic diagram of the sample slide of the present utility model;

[0014] Figure 4 is a side view structural schematic diagram of the fixing frame of the present utility model;

[0015] Figure 5 is a sectional view structural schematic diagram of the fixing frame of the present utility model;

[0016] Figure 6 is a sectional view structural schematic diagram of the pressing plate of the present utility model.

[0017] Among them, 1. Fixing frame; 2. Heating sheet; 3. Sample slide; 4. Liquid cover film; 5. Push-pull plate; 6. Pressing plate; 7. Reagent kit; 8. Test tube slot; 9. Spring; 10. Pressing block; 11. Protective layer; 12. Connecting block; 13. Driving block; 14. Reciprocating screw rod; 15. Connecting rod; 16. Protective block; 17. Threaded rod; 18. Gear cylinder; 19. Magnet; 20. Placing plate; 21. Support rod. Detailed Embodiment

[0018] Next, the technical solutions in the embodiments of the present utility model will be clearly and completely described in conjunction with the accompanying drawings in the embodiments of the present utility model. Obviously, the described embodiments are only a part of the embodiments of the present utility model, rather than all of the embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative efforts shall fall within the protection scope of the present utility model.

[0019] Please refer to Figures 1 to 6, the present utility model provides a liquid cover film independent temperature control dynamic mixing device; it includes a fixing frame 1 and heating sheets 2 equidistantly arranged on the upper surface of the fixing frame 1. A sample slide 3 is arranged on the upper surface of the heating sheet 2. Among them, the heating sheet 2 can heat the sample slide 3 separately, which is convenient for controlling the temperature required for the use of the sample slide 3. A groove is opened on the upper surface of the heating sheet 2 as shown in the appendix Figure 1 , a protrusion is fixedly connected to the lower surface of the sample slide 3 (as shown in the appendix Figure 3 ), and it is buckled with the groove. In this way, when using the sample slide 3, its shaking can be reduced.

[0020] A liquid cover film 4 is arranged on the upper surface of the sample slide 3. Both ends of the fixing frame 1 are slidably connected with a push-pull plate 5 through slideways. The upper surface of the push-pull plate 5 is detachably connected with the rear end of the liquid cover film 4 through the opened groove.

[0021] As Figure 1 shown, slideways are opened on both sides of the fixing frame 1. Both ends of the push-pull plate 5 are used in cooperation with the slideways through sliding rods (shown in the figure, not labeled). The rear end of the liquid cover film 4 is in an I-shaped shape and is adapted to the groove, which is convenient for disassembly and replacement.

[0022] A driving component is fixedly connected to the lower surface of the fixing frame 1 and is used to drive the push-pull plate 5 to move back and forth, so as to mix the reagent on the surface of the sample slide 3. The rear end of the push-pull plate 5 is movably connected with a pressing plate 6 through a pin shaft and is used in cooperation with the liquid cover film 4.

[0023] The rear end of the push-pull plate 5 is fixedly connected with a reagent kit 7 through a U-shaped plate; a test tube slot 8 is opened on the upper surface of the reagent kit 7, and an anti-slip pad is fixedly connected to the inner wall of the test tube slot 8, which can reduce the damage to the test tube caused by shaking. A pressing component is arranged inside the pressing plate 6 and is used to press the liquid cover film 4. A temperature display is arranged on the side surface of the front end of the fixing frame 1 and is electrically connected to the heating sheet 2.

[0024] As Figure 1 shown, test tube slots (8) of different sizes are opened on the surface of the reagent kit 7, which is convenient for the use of test tubes of different specifications. When the driving component drives the push-pull plate 5 to move back and forth, test tubes can be pre-placed inside the test tube slot 8, which is convenient for mixing the reagent inside and reduces the manual operation steps;

[0025] The rear end of the pressing plate 6 is connected to the push-pull plate 5 through a pin shaft, which is convenient for flipping. By electrically connecting the temperature display with the heating sheet 2, it is convenient to view the temperature when each heating sheet heats the sample slide 3, which is convenient for precise control.

[0026] The pressing component includes a spring 9 fixedly connected inside the pressing plate 6. The bottom end of the spring 9 is fixedly connected with a pressing block 10. A protective layer 11 is fixedly connected to the surface of the bottom end of the pressing block 10 at the part in contact with the liquid cover film 4.

[0027] As Figure 6 shown, when the protective layer 11 at the bottom of the pressing plate 6 contacts the liquid cover film 4, the pressing block 10 compresses the spring 9, and at the same time applies a pressing force to the liquid cover film 4, increasing the stability of the liquid cover film 4 during use. The protective layer 11 at its bottom can reduce the damage caused when pressing on the liquid cover film 4. The surfaces of the sliding rods at both ends of the push-pull plate 5 are fixedly connected with limiting frames. Both ends of the pressing plate 6 can be stuck inside them, and a fastening ring is threadedly connected to one side of the limiting frame. Rotating the fastening ring makes it press against the side plates at both ends of the pressing plate 6, thereby positioning it.

[0028] The driving assembly includes a connecting block 12 fixedly connected to the bottom of the fixed frame 1, a driving block 13 provided on the side of the connecting block 12, and a reciprocating lead screw 14 provided at the output end of the driving block 13. One end of the reciprocating lead screw 14 away from the driving block 13 is inserted into the inner part of the side plate at the bottom of the fixed frame 1. A connecting rod 15 is sleeved on the surface of the reciprocating lead screw 14 away from the driving block 13. The other end of the connecting rod 15 is fixedly connected to the bottom of the push-pull plate 5. A protective block 16 is fixedly connected to the surface of the reciprocating lead screw 14 near the connecting block 12, and its top is fixedly connected to the lower surface of the fixed frame 1. A partition is fixedly connected between the upper surface of the fixed frame 1 and the sample slide 3, and a heat insulation layer is provided inside.

[0029] As Figures 4 - 5 shown, a stud is provided inside the connecting rod 15, and a slideway adapted to the stud is provided on the surface of the reciprocating lead screw 14. When the reciprocating lead screw 14 rotates, the connecting rod 15 reciprocates on its surface through the stud. Starting the driving block 13 drives the reciprocating lead screw 14 to rotate, and the connecting rod 15 is used to drive the push-pull plate 5 to reciprocate synchronously, so as to mix the reagent on the surface of the sample slide 3;

[0030] It should be noted that by arranging the sample slide 3 on the upper surface of a plurality of heating sheets 2, the temperature required for the heating sheet 2 to heat the sample slide 3 can be independently controlled (the external control module can be used to be electrically connected to the temperature display and the heating sheet for control). Moreover, the heat insulation layer provided between the heating sheets 2 can reduce the temperature transfer between the heating sheets. Driving the liquid cover film 4 to move back and forth by the driving assembly facilitates the simultaneous mixing of the reagents on the surfaces of a plurality of sample slides 3, improving the use efficiency;

[0031] The sample slide 3 is slightly larger than the heating sheet 2, and the size of the sample slide 3 is 2.5mm * 7.5mm * 1.1mm.

[0032] A threaded rod 17 is inserted into the interior of the protective block 16. A gear cylinder 18 is sleeved on the surface of the reciprocating lead screw 14 near the threaded rod 17. Magnets 19 that attract each other are provided on the end of the gear cylinder 18 away from the protective block 16 and on the side wall of the connecting block 12. The end of the threaded rod 17 away from the protective block 16 is threadedly connected to a placement plate 20. A support rod 21 is fixedly connected to the part of the fixing frame 1 near the placement plate 20.

[0033] As Figures 4 - 5 shown, bevel gears are fixedly connected to the ends of the threaded rod 17 and the gear cylinder 18 that penetrate into the protective block 16. When the gear cylinder 18 is pushed to be meshed and connected with the bevel gear at one end of the threaded rod 17, when the reciprocating lead screw 14 rotates, the threaded rod 17 is synchronously driven to rotate. At this time, the placement plate 20 extends towards both sides of the fixing frame 1, facilitating the placement of the utensils required for use. When it is necessary to retract the placement plate 20, reverse the reciprocating lead screw 14. The magnets 19 on one end of the protective block 16 and on one side of the connecting block 12 attract each other, which can limit the position of the gear cylinder 18, so that the end with the bevel gear is separated from the end of the threaded rod 17 with the bevel gear, preventing the placement plate 20 from being in a telescopic state all the time. The support rod 21 can be used to support the placement plate 20 to maintain stability during use;

[0034] All the electrical components appearing in this text are electrically connected to an external main controller and 220V mains electricity, and the main controller can be a conventional known device such as a computer for control.

[0035] In the present utility model, the working steps of the device are as follows:

[0036] During use, the sample slide 3 is placed above the heating sheet 2. Then, a reagent is added to its upper surface using a reagent needle. Immediately afterwards, a liquid cover film 4 is covered on its upper surface, and its rear end is stuck in a groove formed on the upper surface of the push-pull plate 5. Then, the pressing plate 6 rotates to above the liquid cover film 4 to press it tightly. The test tube that needs to be pre-mixed can be placed inside the reagent kit 7. The driving block 13 is started to drive the reciprocating lead screw 14 to rotate, synchronously driving the push-pull plate 5 to reciprocate back and forth to mix the reagent on the surface of the sample slide 3, and then the heating sheet 2 is powered on to heat the sample slide.

[0037] Although the embodiments of the present utility model have been shown and described, for those of ordinary skill in the art, it can be understood that various changes, modifications, substitutions, and variations can be made to these embodiments without departing from the principles and spirit of the present utility model. The scope of the present utility model is defined by the appended claims and their equivalents.

Claims

1. Liquid cover membrane independent temperature control dynamic mixing device, characterized by: It comprises a fixing frame (1) and a heating plate (2) equidistantly arranged on the upper surface of the fixing frame (1); a sample glass slide (3) is arranged on the upper surface of the heating plate (2); a liquid cover film (4) is arranged on the upper surface of the sample glass slide (3); push-pull plates (5) are slidably connected to the two ends of the fixing frame (1) via a slideway; the upper surface of the push-pull plate (5) is detachably connected to the rear end of the liquid cover film (4) via a groove provided therein; The lower surface of the fixed frame (1) is fixedly connected to a driving assembly and is used to drive the push-pull plate (5) to move forward and backward, so that the reagent on the surface of the sample glass slide (3) is mixed. The rear end of the push-pull plate (5) is movably connected to a pressing plate (6) via a pin shaft and is used in conjunction with a liquid cover film (4). The rear end of the push-pull plate (5) is fixedly connected to a reagent box (7) via a U-shaped plate.

2. The liquid cover film independent temperature control dynamic mixing device according to claim 1, characterized in that: The upper surface of the reagent box (7) is provided with a test tube groove (8), and an anti-slip pad is fixedly connected to the inner wall of the test tube groove (8). A clamping assembly is provided inside the pressing plate (6) for clamping the liquid cover film (4). A temperature display is provided on the side of the front end of the fixing frame (1) and is electrically connected to the heating plate (2).

3. The liquid cover film independent temperature control dynamic mixing device according to claim 2, characterized in that: The clamping assembly comprises a spring (9) fixedly connected to the inside of the pressure plate (6); the bottom end of the spring (9) is fixedly connected to a clamping block (10); and the surface of the bottom end of the clamping block (10) and the portion in contact with the liquid cover membrane (4) are fixedly connected to a protective layer (11).

4. The liquid cover film independent temperature control dynamic mixing device according to claim 1, characterized in that: The driving assembly comprises a connecting block (12) fixedly connected to the bottom of the fixing frame (1), a driving block (13) arranged on the side of the connecting block (12), and a reciprocating screw rod (14) arranged at the output end of the driving block (13), wherein one end of the reciprocating screw rod (14) away from the driving block (13) is inserted into the interior of the bottom side plate of the fixing frame (1).

5. The liquid cover film independent temperature control dynamic mixing device according to claim 4, characterized in that: A connecting rod (15) is sleeved on the surface of one end of the reciprocating screw rod (14) away from the driving block (13), and the other end of the connecting rod (15) is fixedly connected to the bottom of the push-pull plate (5).

6. The liquid cover film independent temperature control dynamic mixing device according to claim 5, characterized in that: A protective block (16) is fixedly connected to the surface of the reciprocating screw rod (14) near the connecting block (12), and its top is fixedly connected to the lower surface of the fixing frame (1). A partition is fixedly connected between the upper surface of the fixing frame (1) and the sample glass slide (3), and a heat insulation layer is provided inside.

7. The liquid cover film independent temperature control dynamic mixing device according to claim 6, characterized in that: A threaded rod (17) is inserted into the interior of the protection block (16), a gear cylinder (18) is sleeved on the surface of the reciprocating screw rod (14) near the threaded rod (17), and magnets (19) that attract each other are provided on one end of the gear cylinder (18) away from the protection block (16) and the side wall of the connecting block (12).

8. The liquid cover film independent temperature control dynamic mixing device according to claim 7, characterized in that: One end of the threaded rod (17) away from the protection block (16) is threadedly connected to a placement plate (20), and a portion of the fixing frame (1) close to the placement plate (20) is fixedly connected to a support rod (21).

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