Dispersion chamber

Abstract

The utility model discloses a dispersion chamber. The dispersion chamber comprises: a glass slide placing disc, the top surface of which is provided with a plurality of glass slide placing grooves; the water cooling disc is connected to the bottom surface of the glass slide placing disc; the heating plate is arranged on one side, deviating from the glass slide placing plate, of the water cooling plate; and the humidity adjusting device is arranged below the heating sheet. The water cooling plate and the heating plate are arranged below the glass slide placing plate, the heating plate can control the temperature rise of the glass slide placing plate, the water cooling plate can control the temperature reduction of the glass slide placing plate, the heating and cooling effects are stable, the humidity adjusting device is arranged, the humidity can be effectively controlled, and the humidity adjusting effect is good. The water cooling disc, the heating sheet and the humidity adjusting device are arranged adjacent to the glass slide placing disc, so that the temperature and humidity can be quickly adjusted, and the preparation efficiency of the sample suspension dropping sheet is improved.

Description

Technical Field

[0001] The present application relates to the technical field of biological treatment equipment, and particularly relates to a dispersion chamber. Background Art

[0002] In the automatic dropping process of peripheral blood lymphocyte samples in cytogenetic analysis, a dispersion chamber is required to provide a stable temperature and humidity condition for the cell samples on the glass slide to prepare a sample suspension dropping. The current solution is to set a glass slide placement tray on the dispersion chamber, place the glass slide on the glass slide placement tray, and set a heating device and a cooling device around the dispersion chamber. However, the current heating effect of the dispersion chamber is unstable and the cooling effect is poor. The main reason is that the heating device and the cooling device are far away from the glass slide placement tray, and the heating device cannot cool down quickly, resulting in slow temperature adjustment and poor cooling effect. For processing a large number of different cell samples under different temperature and humidity conditions, the dispersion chamber needs to quickly adjust the temperature and humidity to meet the use requirements of preparing different cell sample suspension drops. Therefore, there is an urgent need to provide a dispersion chamber that can quickly adjust the temperature and humidity to improve the efficiency of preparing different cell sample suspension drops. Utility Model Content

[0003] The embodiment of the present application provides a dispersion chamber, which can solve the technical problems that the current dispersion chamber has unstable heating effect, poor cooling effect, and cannot quickly adjust the temperature and humidity to meet the use requirements of preparing different cell sample suspension drops, resulting in low efficiency of preparing sample suspension drops.

[0004] The embodiment of the present application provides a dispersion chamber, including:

[0005] A glass slide placement tray, on the top surface of which there are a plurality of glass slide placement grooves;

[0006] A water-cooling plate, connected to the bottom surface of the glass slide placement tray;

[0007] A heating sheet, arranged on the side of the water-cooling plate away from the glass slide placement tray;

[0008] A humidity adjustment device, arranged below the heating sheet.

[0009] Further, the dispersion chamber further includes:

[0010] A rotating shaft, vertically connected to the glass slide placement tray;

[0011] A driving mechanism, connected to the side of the rotating shaft away from the glass slide placement tray; the driving mechanism drives the rotating shaft to rotate and drives the glass slide placement tray to rotate.

[0012] Further, the water-cooling plate and the heating sheet are integrally connected to form an integral structure. The water-cooling plate is provided with a central hole, the heating sheet is arranged along the edge of the water-cooling plate, and the rotating shaft passes through the central hole and is connected to the bottom surface of the glass slide placing plate.

[0013] Further, a plurality of glass slide placing grooves are circumferentially arranged at equal intervals on the top surface of the glass slide placing plate, and the bottom of the glass slide placing groove slopes downward from the inside to the outside; the cross-sectional area of the glass slide placing groove decreases from top to bottom.

[0014] Further, a notch is formed on the outside of the glass slide placing groove, the notch penetrates through the inside and outside in the radial direction of the glass slide placing plate, and the bottom of the notch is flush with the bottom of the glass slide placing groove; a circular groove matching the number of the glass slide placing grooves is formed on the glass slide placing plate; the circular groove is communicated with the inside of the glass slide placing groove.

[0015] Further, the dispersion chamber further includes:

[0016] A bottom plate, which is arranged parallel to the heating sheet; the humidity adjusting device is arranged between the bottom plate and the heating sheet;

[0017] Support columns, which are arranged between the bottom plate and the heating sheet;

[0018] Side plates, which are connected to the edge of the bottom plate and surround the glass slide placing plate;

[0019] A top plate, which is connected to the edge of the side plate and is located above the glass slide placing plate; the top plate is successively provided with a glass slide placing port, a liquid dropping port and a glass slide taking-out port along the circumferential direction. The glass slide placing port is located in the front side area at the center of the top plate, and the liquid dropping port and the glass slide taking-out port are located on the left and right sides of the glass slide placing port.

[0020] Further, the humidity adjusting device includes:

[0021] A humidifying module, which is arranged on the bottom plate;

[0022] A dehumidifying module, which is arranged on the bottom plate; the humidifying module and the dehumidifying module are located on both sides of the rotating shaft.

[0023] Further, the dispersion chamber further includes:

[0024] A water supply device, which is connected to the water-cooling plate, the humidifying module and the dehumidifying module.

[0025] Further, the water supply device includes:

[0026] A first water pump, which is connected to the water inlet of the humidifying module and is arranged on the bottom plate;

[0027] A second water pump, connected to the water inlet of the dehumidification module and disposed on the bottom plate;

[0028] A third water pump, connected to the water inlet of the water-cooled plate.

[0029] Further, the water supply device further includes:

[0030] A distilled water tank, connected to the first water pump;

[0031] A water chiller, whose output port is connected to the second water pump and the third water pump, and whose input port is connected to the water outlet of the dehumidification module and the water outlet of the water-cooled plate.

[0032] The dispersion chamber provided by the embodiment of the present application can control the temperature rise of the slide placement tray through the heating sheet and control the temperature drop of the slide placement tray through the water-cooled plate by arranging the water-cooled plate and the heating sheet under the slide placement tray. The heating and cooling effects are stable, and the humidity adjustment device can effectively control the humidity. The water-cooled plate, the heating sheet and the humidity adjustment device are arranged adjacent to the slide placement tray to achieve rapid adjustment of temperature and humidity, improving the preparation efficiency of the sample suspension droplet film. Description of the Drawings

[0033] The following will make the technical solutions and other beneficial effects of the present application obvious by describing the specific embodiments of the present application in detail in conjunction with the drawings.

[0034] Figure 1 It is a front view structural schematic diagram of the dispersion chamber provided by the embodiment of the present application.

[0035] Figure 2 It is an internal structural schematic diagram of the dispersion chamber provided by the embodiment of the present application.

[0036] Figure 3 It is an internal structural schematic diagram of the dispersion chamber provided by the embodiment of the present application after removing the slide placement tray.

[0037] Figure 4 It is a structural schematic diagram of the bottom plate of the dispersion chamber provided by the embodiment of the present application.

[0038] Figure 5 It is a structural schematic diagram of the slide placement tray provided by the embodiment of the present application.

[0039] Figure 6 It is a structural schematic diagram of the water-cooled plate provided by the embodiment of the present application.

[0040] Figure 7 It is a bottom view of the dispersion chamber provided by the embodiment of the present application.

[0041] Figure 8Schematic connection structure diagram of the water supply device for the dispersion chamber provided by the embodiment of the present application.

[0042] Figure 9 Functional schematic diagram of the dispersion chamber provided by the embodiment of the present application.

[0043] The identifications in the figure are as follows:

[0044] Slide placement tray 1, slide placement groove 11, round groove 12, notch 13, water-cooling plate 2, central hole 21, cooling circuit 22, heating sheet 3, humidity adjustment device 4, humidification module 41, dehumidification module 42, rotating shaft 5, driving mechanism 6, bottom plate 7, support column 71, side plate 8, water supply device 9, first water pump 91, second water pump 92, third water pump 93, distilled water tank 94, water chiller 95, tee 96. Detailed implementation manners

[0045] Next, the technical solutions in the embodiments of the present application will be clearly and completely described in conjunction with the accompanying drawings in the embodiments of the present application. Obviously, the described embodiments are only a part of the embodiments of the present application, rather than all the embodiments. Based on the embodiments in the present application, all other embodiments obtained by those skilled in the art without creative efforts belong to the scope of protection of the present application.

[0046] In the description of the present application, it should be noted that, unless otherwise clearly defined and limited, the terms "installation", "connection", and "connection" should be understood in a broad sense. For example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection, an electrical connection, or communication with each other; it can be directly connected, or indirectly connected through an intermediate medium, and it can be the internal communication of two components or the interaction relationship between two components. For those of ordinary skill in the art, the specific meanings of the above terms in the present application can be understood according to specific situations.

[0047] In the present application, unless otherwise clearly defined and limited, the first feature being "above" or "below" the second feature may include direct contact between the first and second features, or may include the situation where the first and second features are not in direct contact but in contact through other features between them. Moreover, the first feature being "above", "above", and "on" the second feature includes the first feature being directly above and obliquely above the second feature, or simply indicating that the horizontal height of the first feature is higher than that of the second feature. The first feature being "below", "below", and "under" the second feature includes the first feature being directly below and obliquely below the second feature, or simply indicating that the horizontal height of the first feature is lower than that of the second feature.

[0048] Specifically, please refer to Figures 1 to 8 , the embodiment of the present application provides a dispersion chamber, and the dispersion chamber includes:

[0049] A glass slide placement tray 1, the top surface of which is provided with a plurality of glass slide placement grooves 11;

[0050] A water-cooling plate 2, connected to the bottom surface of the glass slide placement tray 1;

[0051] A heating sheet 3, arranged on the side of the water-cooling plate 2 away from the glass slide placement tray 1;

[0052] A humidity adjustment device 4, arranged below the heating sheet 3.

[0053] Among them, by arranging the water-cooling plate 2 and the heating sheet 3 below the glass slide placement tray 1, the heating sheet 3 can be used to control the temperature rise of the glass slide placement tray 1, and the water-cooling plate 2 can be used to control the temperature drop of the glass slide placement tray 1. The heating and cooling effects are stable. Moreover, the arrangement of the humidity adjustment device 4 can effectively control the humidity. The adjacent arrangement of the water-cooling plate 2, the heating sheet 3 and the humidity adjustment device 4 and the glass slide placement tray 1 can realize the rapid adjustment of temperature and humidity, improving the preparation efficiency of the sample suspension droplet film.

[0054] Furthermore, the dispersion chamber further includes:

[0055] A rotating shaft 5, perpendicularly connected to the glass slide placement tray 1;

[0056] A driving mechanism 6, connected to the side of the rotating shaft 5 away from the glass slide placement tray 1; the driving mechanism 6 drives the rotating shaft 5 to rotate to drive the glass slide placement tray 1 to rotate.

[0057] By arranging the driving mechanism 6 and the rotating shaft 5, the glass slide placement tray 1 can be made rotary, effectively shortening the length of the travel trajectory and the action time during the operation of the liquid transfer device and the glass slide picking and placing device. The glass slide can be placed in the glass slide placement groove 11 in a rotating manner, thereby increasing the processing capacity of the glass slide. That is, the throughput of the film-making process is realized, and high-throughput film-making is achieved. By driving the liquid transfer device and the glass slide picking and placing device with independent three-dimensional translation mechanisms, the operation efficiency is further improved, and droplet dropping and glass slide picking and placing can be carried out simultaneously, greatly improving the processing efficiency.

[0058] Furthermore, the water-cooling plate 2 and the heating sheet 3 are integrally connected to form an integral structure. The water-cooling plate 2 is provided with a central hole 21, the heating sheet 3 is arranged along the edge of the water-cooling plate 2, and the rotating shaft 5 passes through the central hole 21 and is connected to the bottom surface of the glass slide placement tray 1.

[0059] The integral structure of the water-cooling plate 2 and the heating sheet 3 can enable the heating sheet 3 to effectively heat the water-cooling plate 2, and then conduct heat to the glass slide placement tray 1. Moreover, the water-cooling plate 2 can be quickly cooled through water circulation, and the water circulation mode in the water-cooling plate 2 can realize stable heating and cooling effects.

[0060] The water-cooled plate 2 is provided with a cooling circuit 22, and the two ends of the cooling circuit 22 are respectively a water inlet and a water outlet.

[0061] Furthermore, a plurality of slide placement grooves 11 arranged circumferentially at equal intervals are provided on the top surface of the slide placement plate 1, and the bottom of the slide placement groove 11 slopes downward from the inside to the outside; this facilitates the flow of the sample liquid after dropping, improves the coverage of the sample on the slide, and is convenient for subsequent analysis. The cross-sectional area of the slide placement groove 11 decreases from top to bottom, which is convenient for placing the slide into the slide placement groove 11.

[0062] Furthermore, a notch 13 is provided on the outside of the slide placement groove 11, the notch 13 penetrates inside and outside in the radial direction of the slide placement plate 1, and the bottom of the notch 13 is flush with the bottom of the slide placement groove 11; this is convenient for draining liquid. A circular groove 12 matching the number of the slide placement grooves 11 is provided on the slide placement plate 1; the circular groove 12 communicates with the inside of the slide placement groove 11. The circular groove 12 is convenient for manually taking out the slide from the inside of the slide placement groove 11.

[0063] Furthermore, the dispersion chamber further includes:

[0064] A bottom plate 7, arranged parallel to the heating sheet 3; the humidity adjustment device 4 is arranged between the bottom plate 7 and the heating sheet 3;

[0065] Support columns 71, arranged between the bottom plate 7 and the heating sheet 3;

[0066] Side plates 8, connected to the edge of the bottom plate 7 and surrounding the slide placement plate 1;

[0067] A top plate, connected to the edge of the side plates 8 and located above the slide placement plate 1; the top plate is successively provided with a slide placement opening, a liquid dropping opening, and a slide taking-out opening along the circumferential direction. The slide placement opening is located in the front side area at the center of the top plate, and the liquid dropping opening and the slide taking-out opening are located on the left and right sides of the slide placement opening.

[0068] Among them, the bottom plate 7, the side plates 8, and the top plate form a sample processing cavity. The liquid transfer device and the slide taking and placing device are arranged on the left and right. The liquid transfer device can be correspondingly arranged with the liquid dropping opening, and the slide taking and placing device is correspondingly arranged with the slide placement opening and the slide taking-out opening. This facilitates the zoning of the liquid transfer area and the slide placement area and controls the interference during the movement of the liquid transfer device and the slide placement device.

[0069] Furthermore, the humidity adjustment device 4 includes:

[0070] The humidification module 41 is provided on the bottom plate 7;

[0071] The dehumidification module 42 is provided on the bottom plate 7; the humidification module 41 and the dehumidification module 42 are located on both sides of the rotating shaft 5.

[0072] The humidification module 41 can increase the air humidity in the sample processing cavity, and the dehumidification module 42 can filter the air in the sample processing cavity to reduce the air humidity.

[0073] Further, the dispersion chamber further includes:

[0074] The water supply device 9 is connected to the water-cooled plate 2, the humidification module 41 and the dehumidification module 42.

[0075] Further, the water supply device 9 includes:

[0076] The first water pump 91 is connected to the water inlet of the humidification module 41 and is provided on the bottom plate 7;

[0077] The second water pump 92 is connected to the water inlet of the dehumidification module 42 and is provided on the bottom plate 7;

[0078] The third water pump 93 is connected to the water inlet of the water-cooled plate 2 and is provided on the bottom plate 7.

[0079] Further, the water supply device 9 further includes:

[0080] The distilled water tank 94 is connected to the first water pump 91;

[0081] The water chiller 95, its output port is connected to the second water pump 92 and the third water pump 93, and its input port is connected to the water outlet of the dehumidification module 42 and the water outlet of the water-cooled plate 2.

[0082] It can be understood that the water supply device 9 can be set to further include: a three-way joint 96, and the three-way joint 96 is respectively connected to the second water pump 92, the third water pump 93, the water outlet of the dehumidification module 42 and the water outlet of the water-cooled plate 2.

[0083] The working principle is as follows: The slide picking and placing device automatically picks up a slide from the slide stack rack, transports it through the three-dimensional translation mechanism for picking and placing, and then enters the interior of the sample processing chamber through the slide placement opening of the sample processing chamber, and places the slide on the placement groove of the slide tray. The slide placement tray rotates circumferentially. After the slide rotates to the liquid dropping station, the three-dimensional translation mechanism for pipetting drives the pipetting mechanism to move. After the pipetting mechanism sucks the liquid, the liquid passes through the liquid dropping port and is delivered to the slide directly opposite the liquid dropping port. The environment inside the sample processing chamber is under the condition of set temperature and humidity. The sample volatilizes under the condition of set temperature and humidity, and the chromosomes are dispersed. The slide placement tray continues to rotate circumferentially and rotates to the slide extraction opening. The slide picking and placing device is controlled to automatically pick up the slide from the slide tray, leave the sample processing chamber after transportation through the slide extraction opening of the sample processing chamber, and place the slides into the corresponding shelves of the slide rack respectively.

[0084] In the dispersion chamber provided by the embodiment of the present application, by arranging a water-cooling plate 2 and a heating sheet 3 below the slide placement tray 1, the temperature of the slide placement tray 1 can be controlled to rise through the heating sheet 3, and the temperature of the slide placement tray 1 can be controlled to drop through the water-cooling plate 2. The heating and cooling effects are stable. Moreover, by arranging a humidity adjusting device 4, the humidity can be effectively controlled. The water-cooling plate 2, the heating sheet 3 and the humidity adjusting device 4 are arranged adjacent to the slide placement tray 1 to achieve rapid adjustment of temperature and humidity, and the preparation efficiency of the sample suspension dropping on the slide is improved.

[0085] In the above embodiments, the descriptions of the respective embodiments have their own focuses. For the parts not detailed in a certain embodiment, reference can be made to the relevant descriptions of other embodiments.

[0086] The above has introduced in detail a dispersion chamber provided by the embodiment of the present application. Specific examples are used in this article to elaborate on the principle and implementation manner of the present application. The description of the above embodiments is only used to help understand the technical solution and its core idea of the present application; those of ordinary skill in the art should understand that: they can still modify the technical solutions recorded in the foregoing embodiments, or perform equivalent replacements on some of the technical features; and these modifications or replacements do not make the essence of the corresponding technical solutions deviate from the scope of the technical solutions of the embodiments of the present application.

Claims

1. A dispersion chamber, characterized in that: The dispersion chamber comprises: A glass slide placement tray, the top surface of which is provided with a plurality of glass slide placement slots; A water cooling plate connected to the bottom surface of the slide placement plate; A heating plate is arranged on a side of the water cooling plate away from the glass slide placement plate; The humidity regulating device is arranged below the heating plate.

2. The dispersion chamber according to claim 1, characterized in that The dispersion chamber also includes: A rotating shaft is vertically connected to the slide placement plate; The driving mechanism is connected to the side of the rotating shaft away from the slide placement tray; the driving mechanism drives the rotating shaft to rotate and drives the slide placement tray to rotate.

3. The dispersion chamber according to claim 2, characterized in that The water cooling plate and the heating plate are connected to each other to form an integral structure. The water cooling plate is provided with a central hole. The heating plate is arranged along the edge of the water cooling plate. The rotating shaft tube passes through the central hole and is connected to the bottom surface of the slide placement plate.

4. The dispersion chamber according to claim 1, characterized in that The top surface of the slide placement plate is provided with a plurality of slide placement grooves which are arranged circumferentially at equal intervals, and the bottom of the slide placement grooves is inclined downward from the inside to the outside; and the cross-sectional area of ​​the slide placement grooves decreases from top to bottom.

5. The dispersion chamber according to claim 1, characterized in that A notch is provided on the outside of the glass slide placement groove, and the notch penetrates inside and outside in the radial direction of the glass slide placement plate, and the bottom of the notch is flush with the bottom of the glass slide placement groove; circular grooves matching the number of the glass slide placement grooves are provided on the glass slide placement plate; the circular grooves are connected to the inner sides of the glass slide placement grooves.

6. The dispersion chamber according to claim 1, wherein: The dispersion chamber also includes: The bottom plate is arranged parallel to the heating plate; the humidity regulating device is arranged between the bottom plate and the heating plate; A support column, disposed between the bottom plate and the heating plate; A side plate connected to the edge of the bottom plate and arranged around the slide placement tray; A top plate is connected to the edge of the side plate and is located above the slide placement tray; the top plate is provided with a slide placement inlet, a dripping port and a slide removal port in sequence along the circumferential direction, the slide placement inlet is located in the front area of ​​the center of the top plate, and the dripping port and the slide removal port are located on the left and right sides of the slide placement inlet.

7. The dispersion chamber according to claim 2, characterized in that The humidity regulating device comprises: A humidification module is arranged on the bottom plate; The dehumidification module is arranged on the bottom plate; the humidification module and the dehumidification module are located on both sides of the rotating shaft.

8. The dispersion chamber according to claim 7, characterized in that The dispersion chamber also includes: A water supply device is connected to the water cooling plate, the humidification module and the dehumidification module.

9. The dispersion chamber according to claim 8, characterized in that The water supply device comprises: a first water pump connected to the water inlet of the humidification module and disposed on the bottom plate; a second water pump connected to the water inlet of the dehumidification module and disposed on the bottom plate; The third water pump is connected to the water inlet of the water cooling disk.

10. The dispersion chamber according to claim 9, characterized in that The water supply device also includes: a distilled water tank connected to the first water pump; The water cooler has an output port connected to the second water pump and the third water pump, and an input port connected to the water outlet of the dehumidification module and the water outlet of the water cooling disk.

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