Cell centrifugal separation device for gene detection

Abstract

The utility model relates to a cell centrifugal separation device for gene detection, which relates to the technical field of cell centrifugal separation and comprises a centrifugal disc, a stable clamping mechanism is arranged at the top of the centrifugal disc and comprises four electric three-jaw chucks fixed at the top of the centrifugal disc, and three clamping blocks are arranged at the tops of the four electric three-jaw chucks in a sliding manner. A plurality of clamping blocks are arranged in the centrifugal disc, buffering pads are arranged in the multiple clamping blocks, four mounting clamping blocks are fixedly arranged on each buffering pad, four clamping grooves are formed in each clamping block, and a protective shell is arranged outside the centrifugal disc. The stable clamping mechanism can be used for clamping test tubes of different specifications, the buffer pad is arranged on the clamping block, the buffer pad can play a role in buffering, the problem that the clamping block clamps the test tubes to be broken due to too large clamping force is effectively solved, meanwhile, the buffer pad can reduce the gap between the surfaces of the test tubes and the buffer pad, and the test tubes can be stably clamped. And the clamping tightness is effectively improved.

Description

Technical Field

[0001] The utility model relates to the technical field of cell centrifugal separation, in particular to a cell centrifugal separation device for gene detection. Background Technique

[0002] A centrifugal separation device is a machine that uses centrifugal force to separate the components in a mixture of liquid and solid particles or liquid and liquid. In cell separation, a centrifuge is needed to perform centrifugal separation on cells to facilitate the extraction and detection of substances inside the cells.

[0003] After retrieval, the patent with the publication number of CN210005329U discloses a separation device for blood cells. This utility model can effectively fix test tubes, improve the centrifugal separation effect, have a high working quality, generate less vibration during operation, prevent the base from colliding violently with the desktop, and have less working noise.

[0004] However, the above separation device has the following defects: The device fixes the test tube by directly inserting the test tube into the test tube slot. This method may cause the test tube to be unstable when the centrifuge rotates at high speed, increasing the risk of accidental detachment, which may damage the test tube or pose a danger to the operator. In addition, the design of the test tube slot limits its flexibility and can only hold test tubes of specific specifications, which restricts the applicability of the device when dealing with test tubes of different sizes. If there are various specifications of test tubes in the laboratory that need to use this equipment, this fixing method is not flexible enough and may require additional adapters or adjustment tools to adapt to test tubes of different sizes. Content of the Utility Model

[0005] The technical problem to be solved by the utility model is to overcome the deficiencies existing in the prior art and provide a cell centrifugal separation device for gene detection.

[0006] The utility model is realized through the following technical solutions:

[0007] A cell centrifugal separation device for gene detection includes a centrifugal disc, and a stable clamping mechanism is arranged on the top of the centrifugal disc;

[0008] The stable clamping mechanism includes four electric three-jaw chucks fixed on the top of the centrifugal disc. Three clamping blocks are slidably arranged on the top of each of the four electric three-jaw chucks. Buffer pads are arranged in multiple clamping blocks. Four mounting blocks are fixed on multiple buffer pads. Four clamping grooves are formed in multiple clamping blocks. A protective housing is arranged outside the centrifugal disc. A workbench is fixed at the bottom of the protective housing. A first servo motor for driving the centrifugal disc is installed at the bottom of the workbench.

[0009] It can be seen that in the above technical solution, when in use, only need to place the test tube on the top of the electric three-jaw chuck, and then the electric three-jaw chuck can shrink inward to clamp the test tube. Through this setting, test tubes of different specifications can be clamped. And a buffer pad is provided on the clamping block, which can play a buffering role, effectively preventing the problem that the clamping block crushes the test tube due to excessive clamping force. At the same time, the buffer pad can reduce the gap between the surface of the test tube and the buffer pad, effectively improving the clamping tightness. And the buffer pad and the clamping block are clamped through a card slot and a mounting block. Through this setting, the service life of the equipment can be extended and the maintenance cost can be reduced.

[0010] Optionally, a second servo motor is fixedly provided at the bottom of the workbench, and a lead screw is fixedly provided at the output end of the second servo motor.

[0011] It can be seen that in the above technical solution, setting the second servo motor can drive the lead screw to rotate.

[0012] Optionally, in a possible implementation manner, a top plate is threadedly connected to the lead screw, a guide post is slidably provided in the top plate, and limit blocks are fixedly provided at the top of the guide post and the lead screw.

[0013] It can be seen that in the above technical solution, sliding the top plate on the guide post can play a guiding role in the sliding of the top plate, and setting the limit blocks can prevent the top plate from falling off the top of the lead screw.

[0014] Optionally, in a possible implementation manner, an upper cover is fixedly provided at the bottom of the top plate, and a rotating shaft is fixedly provided at the bottom of the upper cover.

[0015] It can be seen that in the above technical solution, setting the upper cover facilitates covering the protective housing.

[0016] Optionally, in a possible implementation manner, four positioning blocks are fixedly provided at the bottom of the upper cover, and four positioning grooves are opened at the top of the protective housing.

[0017] It can be seen that in the above technical solution, the positioning blocks can be inserted into the positioning grooves to play a guiding role in the opening and closing of the upper cover.

[0018] Optionally, in a possible implementation manner, a rotating roller is rotatably provided on the rotating shaft, and a receiving groove is fixedly provided at the top of the centrifugal disc.

[0019] It can be seen that in the above technical solution, while the centrifugal disc is rotating, the rotating roller can rotate in the receiving groove at the top of the centrifugal disc to play a guiding role in the rotation of the centrifugal disc, so as to prevent the problem of position deviation of the centrifugal disc after long-term use.

[0020] Optionally, in a possible implementation, support columns are fixedly provided at the four corners of the bottom end of the workbench, and universal wheels are fixedly provided at the bottoms of the four support columns.

[0021] It can be seen that in the above technical solution, support columns are provided to support the device, and universal wheels are provided to facilitate the movement and transportation of the device.

[0022] Technical effects and advantages of the present utility model:

[0023] 1. When the present utility model is in use, only the test tube needs to be placed on the top of the electric three-jaw chuck, and then the electric three-jaw chuck can contract inward to clamp the test tube. Through this setting, test tubes of different specifications can be clamped, and a buffer pad is provided on the clamping block. The buffer pad can play a buffering role, effectively preventing the problem that the clamping block crushes the test tube due to excessive clamping force. At the same time, the buffer pad can reduce the gap between the surface of the test tube and the buffer pad, effectively improving the clamping tightness. And the buffer pad and the clamping block are clamped through the card slot and the installation card block. Through this setting, the service life of the equipment can be extended and the maintenance cost can be reduced;

[0024] 2. After the upper cover of the present utility model is closed, the first servo motor can be turned on to drive the centrifuge disc to rotate, and centrifugation work is performed on the cells in the test tube. While the centrifuge disc is rotating, the rotating roller can rotate in the receiving groove on the top of the centrifuge disc, playing a guiding role in the rotation of the centrifuge disc to prevent the problem of position deviation of the centrifuge disc after long-term use, and improving the service life of the centrifuge and the stability of the centrifugation process. Description of the Drawings

[0025] The structures, ratios, sizes, etc. illustrated in this specification are only used to cooperate with the content disclosed in the specification for those familiar with this technology to understand and read, and are not used to limit the limited conditions under which the present utility model can be implemented. Therefore, they do not have technical substantive significance. Any modification of the structure, change of the proportional relationship, or adjustment of the size, without affecting the effects that the present utility model can produce and the purposes that can be achieved, should still fall within the scope covered by the technical content disclosed in the present utility model.

[0026] Figure 1 is the three-dimensional structure diagram of the overall structure of the present utility model.

[0027] Figure 2 is the semi-sectional structure schematic diagram of the present utility model.

[0028] Figure 3 is the structural schematic diagram of the electric three-jaw chuck of the present utility model.

[0029] Figure 4 is the structural schematic diagram of the clamping block of the present utility model.

[0030] Figure 5 This is a schematic structural diagram of the buffer pad of the present utility model.

[0031] In the figure: 1, centrifugal disc; 2, electric three-jaw chuck; 3, clamping block; 4, buffer pad; 5, mounting block; 6, card slot; 7, protective housing; 8, workbench; 9, first servo motor; 10, second servo motor; 11, lead screw; 12, top plate; 13, guide post; 14, limit block; 15, upper cover; 16, rotating shaft; 17, positioning block; 18, positioning slot; 19, rotating roller; 20, receiving groove; 21, support column; 22, universal wheel. Specific embodiments

[0032] In order to enable those skilled in the art of the present technology to better understand the technical solutions of the present utility model, the following further detailed description of the present utility model is made in conjunction with the accompanying drawings and the best embodiments. Based on the embodiments in the utility model, all other embodiments obtained by those of ordinary skill in the art without making creative efforts fall within the scope of protection of the utility model.

[0033] Embodiment 1

[0034] As Figures 1-5 shown, a cell centrifugal separation device for gene detection includes a centrifugal disc 1, and a stable clamping mechanism is provided on the top of the centrifugal disc 1;

[0035] The stable clamping mechanism includes four electric three-jaw chucks 2 fixed on the top of the centrifugal disc 1. Three clamping blocks 3 are slidably provided on the top of each of the four electric three-jaw chucks 2. Buffer pads 4 are provided in each of the plurality of clamping blocks 3. Four mounting blocks 5 are fixed on each of the plurality of buffer pads 4. Four card slots 6 are opened in each of the plurality of clamping blocks 3. A protective housing 7 is provided outside the centrifugal disc 1. A workbench 8 is fixed at the bottom of the protective housing 7. A first servo motor 9 for driving the centrifugal disc 1 is installed at the bottom of the workbench 8. During use, only need to place the test tube on the top of the electric three-jaw chuck 2, and then the electric three-jaw chuck 2 can contract inward to clamp the test tube. Through this setting, test tubes of different specifications can be clamped. And buffer pads 4 are provided on the clamping blocks 3. The buffer pads 4 can play a buffering role, effectively preventing the problem that the clamping blocks 3 crush the test tube due to excessive clamping force. At the same time, the buffer pads 4 can reduce the gap between the surface of the test tube and the buffer pads, effectively improving the clamping tightness. And the buffer pads 4 and the clamping blocks 3 are clamped through the card slots 6 and the mounting blocks 5. Through this setting, the service life of the equipment can be extended and the maintenance cost can be reduced.

[0036] Embodiment 2

[0037] As Figures 1-5As shown in the figure, a cell centrifugal separation device for gene detection. At the bottom of the workbench 8, a second servo motor 10 is fixedly installed. At the output end of the second servo motor 10, a lead screw 11 is fixedly installed. It is set that the second servo motor 10 can drive the lead screw 11 to rotate. A top plate 12 is threadedly connected to the lead screw 11. A guide post 13 is slidably installed in the top plate 12. Limit blocks 14 are fixedly installed at the top of both the guide post 13 and the lead screw 11, enabling the top plate 12 to slide on the guide post 13, which can play a guiding role in the sliding of the top plate 12. The limit blocks 14 are set to prevent the top plate 12 from falling off the top of the lead screw 11. A top cover 15 is fixedly installed at the bottom of the top plate 12. A rotating shaft 16 is fixedly installed at the bottom of the top cover 15. The top cover 15 is set to facilitate covering the protective housing 7. Four positioning blocks 17 are fixedly installed at the bottom of the top cover 15. Four positioning grooves 18 are opened at the top of the protective housing 7. The positioning blocks 17 can be inserted into the positioning grooves 18, playing a guiding role in the opening and closing of the top cover 15. A rotating roller 19 is rotatably installed on the rotating shaft 16. A receiving groove 20 is fixedly installed at the top of the centrifugal disc 1. While the centrifugal disc 1 is rotating, the rotating roller 19 can rotate in the receiving groove 20 at the top of the centrifugal disc 1, playing a guiding role in the rotation of the centrifugal disc 1 to prevent the problem of the position deviation of the centrifugal disc 1 after long-term use. At the four corners of the bottom end of the workbench 8, support columns 21 are fixedly installed. Universal wheels 22 are fixedly installed at the bottoms of the four support columns 21. The support columns 21 are set to facilitate supporting the device, and the universal wheels 22 can facilitate the movement and transportation of the device.

[0038] The usage process of the embodiment of the present utility model is as follows:

[0039] When the present utility model is in use, only need to place the test tube on the top of the electric three-jaw chuck 2, and then the electric three-jaw chuck 2 can contract inward to clamp the test tube. Through this setting, test tubes of different specifications can be clamped. And a buffer pad 4 is arranged on the clamping block 3. The buffer pad 4 can play a buffering role, effectively preventing the problem that the clamping block 3 crushes the test tube due to excessive clamping force. At the same time, the buffer pad 4 can reduce the gap between the surface of the test tube and the buffer pad, effectively improving the clamping tightness. And the buffer pad 4 and the clamping block 3 are clamped through the clamping groove 6 and the installation clamping block 5. Through this setting, the installation of the buffer pad can be more convenient. When it is necessary to cover the protective housing 7, only need to turn on the second servo motor 10, so that the second servo motor 10 drives the lead screw 11 to rotate, and the lead screw 11 cooperates with the top plate 12 to drive the top cover 15 downward. While covering the top cover 15, the positioning block 17 can be engaged with the positioning groove 18, and the rotating roller 19 can be inserted into the receiving groove 20. When the top cover 15 is completely covered, the first servo motor 9 can drive the centrifugal disc 1 to rotate, performing centrifugal work on the cells in the test tube. While the centrifugal disc 1 is rotating, the rotating roller 19 can rotate in the receiving groove 20 at the top of the centrifugal disc 1, playing a guiding role in the rotation of the centrifugal disc 1 to prevent the problem of the position deviation of the centrifugal disc 1 after long-term use.

[0040] The above are only the preferred embodiments of the present utility model. It should be noted that for those of ordinary skill in the art, without departing from the principle of the present utility model, several improvements and modifications can be made, and these improvements and modifications should also be regarded as the protection scope of the present utility model.

Claims

1. A cell centrifugal separation device for gene detection, comprising a centrifugal disk (1), characterized in that: A stabilizing clamping mechanism is provided on the top of the centrifugal disc (1); The stable clamping mechanism comprises four electric three-jaw chucks (2) fixed on the top of the centrifugal disc (1), three clamping blocks (3) are slidably provided on the top of each of the four electric three-jaw chucks (2), a plurality of the clamping blocks (3) are provided with a buffer pad (4), four mounting blocks (5) are fixedly provided on each of the plurality of buffer pads (4), four clamping slots (6) are provided in each of the plurality of clamping blocks (3), a protective shell (7) is provided outside the centrifugal disc (1), a workbench (8) is fixedly provided at the bottom of the protective shell (7), and a first servo motor (9) for driving the centrifugal disc (1) is installed at the bottom of the workbench (8); The electric three-jaw chuck (2) can be retracted inwards to clamp the test tube. This arrangement can be used to clamp test tubes of different specifications.

2. The cell centrifugal separation device for gene detection according to claim 1, characterized in that: A second servo motor (10) is fixedly provided at the bottom of the workbench (8), and a screw rod (11) is fixedly provided at the output end of the second servo motor (10).

3. The cell centrifugal separation device for gene detection according to claim 2, characterized in that: The screw rod (11) is threadedly connected to a top plate (12), a guide column (13) is slidably provided inside the top plate (12), and a limit block (14) is fixedly provided at the top of the guide column (13) and the screw rod (11).

4. The cell centrifugal separation device for gene detection according to claim 3, characterized in that: An upper cover (15) is fixedly provided at the bottom of the top plate (12), and a rotating shaft (16) is fixedly provided at the bottom of the upper cover (15).

5. The cell centrifugal separation device for gene detection according to claim 4, characterized in that: Four positioning blocks (17) are fixedly provided at the bottom of the upper cover (15), and four positioning grooves (18) are provided at the top of the protective shell (7).

6. The cell centrifugal separation device for gene detection according to claim 4, characterized in that: A rotating roller (19) is rotatably provided on the rotating shaft (16), and a receiving groove (20) is fixedly provided on the top of the centrifugal disc (1).

7. The cell centrifugal separation device for gene detection according to claim 1, characterized in that: Support columns (21) are fixedly provided at the four corners of the bottom end of the workbench (8), and universal wheels (22) are fixedly provided at the bottoms of the four support columns (21).

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