Antibody preservation solution preparation device

Abstract

The antibody preservation solution preparation device comprises a box body and a movable box, the lower surface of the box body is symmetrically connected with supporting columns, the upper surface of the box body is fixedly connected with a main motor and an air pump assembly respectively, the top of an inner cavity of the box body is symmetrically connected with ultraviolet lamps, a feeding port is formed in the upper surface of the box body, and a loading and unloading port is formed in the lower end of the side face of the box body. The moving box is slidably connected into the box body through a moving block, the lower end of the side face of the moving box is fixedly connected with a liquid injection assembly, the upper surface of the moving box is fixedly connected with a sealing layer, and an inner cavity of the moving box is movably connected with a screening frame through a positioning block. Through the cooperation of the box body, the stirring plate, the moving box, the sealing layer, the screening frame, the ultraviolet lamp, the air pump assembly and the liquid injection assembly, the configurator can stir, filter and sterilize mixed liquid at the same time when the configurator configures antibody preservation liquid, so that the configuration efficiency of the antibody preservation liquid is effectively improved.

Description

Technical Field

[0001] The utility model relates to the technical field of antibody preservation solutions, and particularly relates to an antibody preservation solution preparation device. Background Art

[0002] Antibodies are a very important tool in biological research and are widely used in various experiments, such as immunological detection, molecular biology research, and medical diagnosis, etc. Since the essence of an antibody is protein, special attention needs to be paid to its activity and stability during storage to avoid degradation or loss of binding specificity due to improper storage. The main function of an antibody preservation solution is to provide a suitable storage environment for the antibody and reduce the possibility of it being affected by adverse external conditions. Therefore, the correct storage method can maximize the activity of the antibody, thereby ensuring the accuracy and repeatability of experimental results. However, the common configuration method of antibody preservation solutions is mostly manual. During the configuration process of the antibody preservation solution, various raw materials need to be mixed accordingly, and the mixed solution also needs to be filtered and sterilized successively, making the configuration steps rather cumbersome, thus reducing the configuration efficiency of the antibody preservation solution. Content of the Utility Model

[0003] To overcome the defects of the prior art, the present utility model provides an antibody preservation solution preparation device to solve the problems raised in the above background art.

[0004] To achieve the above object, an antibody preservation solution preparation device is provided, including: a box body and a moving box. The lower surface of the box body is symmetrically connected with support columns, and the upper surface of the box body is respectively fixedly connected with a main motor and an air pump assembly. The top of the inner cavity of the box body is symmetrically connected with ultraviolet lamps. The upper surface of the box body is provided with a feeding port, and the lower end of the side surface of the box body is provided with a loading and unloading port. At the same time, two sets of lifting grooves are symmetrically opened on both sides of the inner cavity of the box body. The bottom of the lifting groove is fixedly connected with an electric rod through a groove, and the moving block is slidably connected in the lifting groove through the electric rod. The moving box is slidably connected in the box body through the moving block. The lower end of the side surface of the moving box is fixedly connected with a liquid injection assembly, and the upper surface of the moving box is fixedly connected with a sealing layer. The inner cavity of the moving box is movably connected with a screening frame through a positioning block. At the same time, a transmission shaft is movably connected to the top of the inner cavity of the box body through a sealing bearing. The upper end of the transmission shaft is connected to the main motor through a coupling, and the lower end of the transmission shaft is fixedly connected with a stirring plate through a fixing ring. The surface of the stirring plate is symmetrically connected with stirring blades.

[0005] Preferably, the box body is in a cuboid structure, the loading and unloading port opened on the side surface of the box body is in a square structure, and the two sets of lifting grooves symmetrically opened in the box body are both in a rectangular structure. The groove opened at the bottom of the lifting groove communicates with the lower surface of the box body. At the same time, the moving block is in a rectangular structure, and the size of the moving block is adapted to that of the lifting groove.

[0006] Preferably, the moving box has a concave structure. Limiting grooves are correspondingly formed at positions on both sides of the moving box opposite to the moving blocks, and the limiting grooves are in a strip-shaped structure. Both ends of the limiting grooves communicate with the end faces of both ends of the outer side of the moving box. At the same time, the sizes of the limiting grooves and the moving blocks are adapted to each other.

[0007] Preferably, the sealing layer fixedly connected to the upper surface of the moving box through a groove has a mouth-shaped structure. Two groups of positioning grooves are symmetrically formed on each of the four sides at the upper end of the inner cavity of the moving box. The eight groups of positioning grooves are all in a rectangular structure. At the same time, the sizes of the positioning grooves and the positioning blocks are adapted to each other.

[0008] Preferably, the cross-section of the screening frame has a U-shaped structure. Positioning blocks are correspondingly connected to positions on the outer side of the screening frame opposite to the positioning grooves. The size of the outer side of the screening frame is adapted to the inner cavity of the moving box. The filter plate fixedly connected to the bottom of the screening frame has a square structure. At the same time, the depth of the screening frame is less than the depth of the inner cavity of the moving box. Four groups of pull plates are symmetrically connected to the upper end of the inner cavity of the screening frame, and the four groups of pull plates are all in a triangular prism structure.

[0009] Preferably, the fixing ring fixedly connected to the lower end of the transmission shaft has a circular ring structure. Two groups of stirring plates fixedly connected to both sides of the fixing ring are both in a T-shaped structure. A plurality of stirring blades are fixedly connected to the surface of the stirring plate through grooves in parallel and at equal intervals. At the same time, the stirring blades have a funnel-shaped structure.

[0010] Preferably, an extension plate is movably connected to the outer side of the box body near the loading and unloading port through a bearing. The extension plate has a square structure. A through hole is correspondingly formed on the surface of the extension plate at a position opposite to the liquid injection assembly. The through hole has a cylindrical structure. At the same time, the four support columns fixedly connected to the lower surface of the box body are all in a frustum-shaped structure.

[0011] Compared with the prior art, the beneficial effects of the present utility model are as follows: Through the cooperation of the box body, the moving box, the moving blocks and the electric rods, the moving box can be conveniently loaded and unloaded inside the box body. Through the cooperation of the main motor, the ultraviolet lamp, the transmission shaft, the stirring plates and the stirring blades, the antibody preservation solution can be stirred and sterilized simultaneously during configuration. And through the cooperation of the air pump assembly, the screening frame and the liquid injection assembly, when the configurator divides and fills the antibody protection solution, the antibody preservation solution can be filtered and sterilized synchronously, thereby simplifying the configuration steps and improving the configuration efficiency of the antibody preservation solution. BRIEF DESCRIPTION OF THE DRAWINGS

[0012] Figure 1 It is a front view schematic diagram of an embodiment of the present utility model.

[0013] Figure 2 It is a side view schematic diagram of an embodiment of the present utility model.

[0014] Figure 3 It is a top view schematic diagram of an embodiment of the present utility model.

[0015] Figure 4 For the embodiment of the present utility model Figure 2 Enlarged schematic view of location A

[0016] In the figure: 1, support column; 2, electric rod; 3, box body; 4, lifting groove; 5, moving box; 6, screening frame; 7, stirring plate; 8, moving block; 9, stirring blade; 10, transmission shaft; 11, pull plate; 12, feeding port; 13, ultraviolet lamp; 14, main motor; 15, air pump assembly; 16, liquid injection assembly; 17, extension plate; 18, limiting groove; 19, positioning block; 20, sealing layer Detailed implementation manners

[0017] Referring to Figures 1 to 4 As shown in the figure, the present utility model provides an antibody preservation solution preparation device, including: a box body 3 and a moving box 5. The lower surface of the box body 3 is symmetrically connected with support columns 1, and the upper surface of the box body 3 is respectively fixedly connected with a main motor 14 and an air pump assembly 15. The top of the inner cavity of the box body 3 is symmetrically connected with ultraviolet lamps 13. The upper surface of the box body 3 is provided with a feeding port 12. The lower end of the side surface of the box body 3 is provided with a loading and unloading port. At the same time, the two sides of the inner cavity of the box body 3 are symmetrically provided with lifting grooves 4. The bottom of the lifting groove 4 is fixedly connected with an electric rod 2 through a groove. The moving block 8 is slidably connected in the lifting groove 4 through the electric rod 2. The moving box 5 is slidably connected in the box body 3 through the moving block 8. The lower end of the side surface of the moving box 5 is fixedly connected with a liquid injection assembly 16. The upper surface of the moving box 5 is fixedly connected with a sealing layer 20. The inner cavity of the moving box 5 is movably connected with a screening frame 6 through a positioning block 19. At the same time, the transmission shaft 10 is movably connected to the top of the inner cavity of the box body 3 through a sealing bearing. The upper end of the transmission shaft 10 is connected to the main motor 14 through a coupling. The lower end of the transmission shaft 10 is fixedly connected with a stirring plate 7 through a fixing ring. The surface of the stirring plate 7 is symmetrically connected with stirring blades 9

[0018] In this embodiment, open the cover of the feed inlet 12, inject the corresponding raw materials into the interior of the box body 3 so that the raw materials can converge in the moving box 5, close the feed inlet 12, turn on the ultraviolet lamp 13, and start the switch of the main motor 14. The main motor 14 drives the transmission shaft 10 to rotate through the coupling, and the transmission shaft 10 drives the fixedly connected stirring plates 7 and stirring blades 9 to rotate synchronously through the fixing ring. Then, the raw materials in the moving box 5 can be fully stirred, and corresponding sterilization treatment can also be carried out during the stirring process. After that, dock the container with the liquid injection head of the liquid injection assembly 16, open the solenoid valve, and start the switch of the air pump assembly 15. The air pump assembly 15 injects sterile gas into the interior of the box body 3, so that the air pressure between the moving box 5 and the box body 3 gradually and slowly increases. Then, the antibody protection liquid inside the moving box 5 will sequentially pass through the filter plate of the screening frame 6 and the microfiltration membrane provided in the liquid injection assembly 16 under the action of the air pressure. Then, when filtering the particulate matter that may be generated in the antibody protection liquid, the bacteria in the antibody protection liquid can also be effectively filtered, so as to ensure the quality of the antibody protection liquid after sub-packaging. After the antibody protection liquid is sub-packaged, turn off the main motor 14, the air pump assembly 15, and the ultraviolet lamp 13, rotate the extension plate 17 so that the extension plate 17 changes from the vertical state to the horizontal state, start the switch of the electric rod 2, and the telescopic rod of the electric rod 2 drives the moving box 5 to move synchronously through the moving block 8. After the moving box 5 moves to the bottom of the inner cavity of the box body 3, turn off the electric rod 2, and the worker pulls the moving box 5 to move through the limiting grooves 18 opened on both sides of the moving box 5, so that the moving box 5 can smoothly disengage from the box body 3, which is convenient for subsequent cleaning. At the same time, the air pump assembly 15 is a common brand model on the market, and a corresponding sterilization structure is provided at the air inlet of the air pump assembly 15.

[0019] As a preferred embodiment, the box body 3 is in a cuboid structure, the loading and unloading opening opened on the side of the box body 3 is in a square structure, and the two sets of lifting grooves 4 symmetrically opened in the box body 3 are both in a rectangular structure. The groove opened at the bottom of the lifting groove 4 communicates with the lower surface of the box body 3. At the same time, the moving block 8 is in a rectangular structure, and the size of the moving block 8 is adapted to that of the lifting groove 4.

[0020] In this embodiment, as Figure 1 , Figure 2 and Figure 3 , the opening of the loading and unloading opening enables the moving box 5 to be conveniently loaded and unloaded inside the box body 3, and the size of the lifting groove 4 is adapted to that of the moving block 8, which can assist in enhancing the stability of the moving block 8 when moving.

[0021] As a preferred embodiment, the moving box 5 is in a concave structure. Limiting grooves 18 are correspondingly opened at the positions of the two sides of the moving box 5 relative to the moving block 8. The limiting grooves 18 are in a long strip structure, and both ends of the limiting grooves 18 communicate with the two end faces of the outer side of the moving box 5. At the same time, the size of the limiting grooves 18 is adapted to that of the moving block 8.

[0022] In this embodiment, as Figure 1 , Figure 2 and Figure 3 , the limiting groove 18 opened on the outer side of the moving box 5 enables the moving block 8 to be synchronously embedded into the limiting groove 18 when the moving box 5 is embedded into the interior of the box body 3. Then, during the upward movement of the moving block 8, the moving block 8 can drive the moving box 5 to move upward synchronously through the limiting groove 18.

[0023] As a preferred embodiment, the sealing layer 20 fixedly connected to the upper surface of the moving box 5 through a groove has a mouth-shaped structure. Moreover, two groups of positioning grooves are symmetrically opened on the four sides at the upper end of the inner cavity of the moving box 5, and the eight groups of positioning grooves are all rectangular structures. At the same time, the sizes of the positioning grooves and the positioning blocks 19 are adapted to each other.

[0024] In this embodiment, as Figure 3 and Figure 4 , the sealing layer 20 is made of medical-grade silicone material, which can then assist in enhancing the sealing performance at the connection between the moving box 5 and the top of the inner cavity of the box body 3, ensuring that the air pressure in the inner cavity of the moving box 5 can increase stably.

[0025] As a preferred embodiment, the cross-section of the screening frame 6 has a U-shaped structure. The positioning blocks 19 are correspondingly connected to the positions of the screening frame 6 on the outer side relative to the positioning grooves, and the size of the outer side of the screening frame 6 is adapted to the size of the inner cavity of the moving box 5. Moreover, the filter plate fixedly connected to the bottom of the screening frame 6 has a square structure. At the same time, the depth of the screening frame 6 is less than the depth of the inner cavity of the moving box 5, and four groups of pull plates 11 are symmetrically connected to the upper end of the inner cavity of the screening frame 6, and the four groups of pull plates 11 are all in a triangular prism structure.

[0026] In this embodiment, as Figure 1 , Figure 3 and Figure 4 , the setting of the positioning blocks 19 enables the filter plate at the lower end of the screening frame 6 to be placed above the liquid inlet of the liquid injection assembly 16 when the screening frame 6 is embedded into the moving box 5. When the antibody protection liquid flows into the liquid injection assembly 16, it can be first subjected to corresponding filtration treatment by the filter plate to filter out the possible particulate matters in the antibody protection liquid, improving the quality of the antibody protection liquid. The setting of the pull plates 11 facilitates the removal of the screening frame 6.

[0027] As a preferred embodiment, the fixing ring fixedly connected to the lower end of the transmission shaft 10 has a circular ring structure. The two groups of stirring plates 7 fixedly connected to both sides of the fixing ring are both in a T-shaped structure, and a plurality of stirring blades 9 are fixedly connected to the surface of the stirring plates 7 through grooves in parallel and at equal intervals. At the same time, the stirring blades 9 have a funnel-shaped structure.

[0028] In this embodiment, as Figure 1 and Figure 2, the stirring plate 7 and the stirring blades 9 are provided such that the configurator can fully stir the various raw materials in the moving box 5, improve the uniformity of the various raw materials in the antibody protective solution, and assist in improving the quality of the antibody protective solution.

[0029] As a preferred embodiment, the outer side surface of the box body 3 near the loading and unloading port is movably connected to the extension plate 17 through a bearing. The extension plate 17 has a square structure, and a through hole is correspondingly opened on the surface of the extension plate 17 at a position corresponding to the liquid injection assembly 16. The through hole has a cylindrical structure. At the same time, the four support columns 1 fixedly connected to the lower surface of the box body 3 are all frustum-shaped structures.

[0030] In this embodiment, as Figure 2 and Figure 3 , the setting of the extension plate 17 enables the moving box 5 to be conveniently moved outside the box body 3, avoiding the worker continuously lifting the moving box 5, reducing the labor intensity of the worker when loading and unloading the moving box 5. At the same time, the upper surface of the box body 3 is made of a transparent material, which is convenient for the worker to observe the preparation progress of the antibody protective solution at all times.

[0031] The antibody preservation solution configurator of the present utility model, through the cooperation of the box body 3, the stirring plate 7, the moving box 5, the sealing layer 20, the screening frame 6, the ultraviolet lamp 13, the air pump assembly 15 and the liquid injection assembly 16, enables the configurator to stir, filter and sterilize the mixed solution simultaneously when preparing the antibody preservation solution, thereby effectively improving the preparation efficiency of the antibody preservation solution, reducing the labor intensity of the worker, and also ensuring the overall quality of the antibody protective solution after sub-packaging.

Claims

1. An antibody preservation solution preparer, comprising: The box (3) and the moving box (5) are characterized in that: the lower surface of the box (3) is symmetrically connected to the support column (1), and the upper surface of the box (3) is respectively fixedly connected to the main motor (14) and the air pump assembly (15), and the top of the inner cavity of the box (3) is symmetrically connected to the ultraviolet lamp (13), and the upper surface of the box (3) is provided with a feed port (12), and the lower end of the side of the box (3) is provided with a loading and unloading port, and at the same time, the two sides of the inner cavity of the box (3) are symmetrically provided with lifting grooves (4), the bottom of the lifting groove (4) is fixedly connected to the electric rod (2) through a groove, and the moving block (8) is slidably connected in the lifting groove (4) through the electric rod (2) The movable box (5) is slidably connected to the housing (3) via a movable block (8), and the lower end of the side of the movable box (5) is fixedly connected to the liquid injection assembly (16), and the upper surface of the movable box (5) is fixedly connected to the sealing layer (20), and the inner cavity of the movable box (5) is movably connected to the screening frame (6) via a positioning block (19), and the transmission shaft (10) is movably connected to the top of the inner cavity of the housing (3) via a sealing bearing, the upper end of the transmission shaft (10) is connected to the main motor (14) via a coupling, and the lower end of the transmission shaft (10) is fixedly connected to the stirring plate (7) via a fixing ring, and the surface of the stirring plate (7) is symmetrically connected to the stirring blade (9).

2. The antibody preservation solution dispenser according to claim 1, characterized in that: The box body (3) is of a rectangular structure, and the loading and unloading opening provided on the side of the box body (3) is of a square structure. The two sets of lifting grooves (4) symmetrically provided in the box body (3) are both of a rectangular structure, and the grooves provided at the bottom of the lifting grooves (4) are connected to the lower surface of the box body (3). The moving block (8) is of a rectangular structure, and the sizes of the moving block (8) and the lifting grooves (4) are matched.

3. The antibody preservation solution dispenser according to claim 1, characterized in that: The moving box (5) is of a concave structure, and limiting grooves (18) are provided on both sides of the moving box (5) at positions corresponding to the moving blocks (8), and the limiting grooves (18) are of a long strip structure, with both ends of the limiting grooves (18) connected to both end surfaces of the outer side surface of the moving box (5), and the sizes of the limiting grooves (18) and the moving blocks (8) are matched.

4. The antibody preservation solution dispenser according to claim 1, characterized in that: The sealing layer (20) fixedly connected to the upper surface of the moving box (5) by the groove is in a square shape, and two groups of positioning grooves are symmetrically provided on the four sides of the upper end of the inner cavity of the moving box (5), and the eight groups of positioning grooves are all in a rectangular structure. At the same time, the sizes of the positioning grooves and the positioning blocks (19) are matched.

5. The antibody preservation solution dispenser according to claim 1, characterized in that: The cross section of the screening frame (6) is of a U-shaped structure, the position of the outer side surface of the screening frame (6) relative to the positioning groove corresponds to the connection positioning block (19), and the size of the outer side surface of the screening frame (6) and the inner cavity of the movable box (5) are adapted, and the filter plate fixedly connected to the bottom of the screening frame (6) is of a square structure, and the depth of the screening frame (6) is less than the depth of the inner cavity of the movable box (5), and the upper end of the inner cavity of the screening frame (6) is symmetrically connected to four groups of pull plates (11), and the four groups of pull plates (11) are all of a triangular prism structure.

6. The antibody preservation solution dispenser according to claim 1, characterized in that: The fixing ring fixedly connected to the lower end of the transmission shaft (10) has a circular ring structure, and the two groups of stirring plates (7) fixedly connected on both sides of the fixing ring both have a T-shaped structure. The surfaces of the stirring plates (7) are fixedly connected to multiple groups of stirring blades (9) in parallel and at equal intervals via grooves, and the stirring blades (9) have a funnel-shaped structure.

7. The antibody preservation solution dispenser according to claim 1, characterized in that: The outer side surface of the box body (3) is movably connected to an extension plate (17) via a bearing near the loading and unloading port. The extension plate (17) has a square structure, and a through hole is provided on the surface of the extension plate (17) corresponding to the position of the injection assembly (16). The through hole has a cylindrical structure. At the same time, the four groups of support columns (1) fixedly connected to the lower surface of the box body (3) are all truncated cone structures.

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