Device for preventing muscle injury of laboratory mouse

Abstract

The utility model discloses a device for manufacturing laboratory mouse muscle injury, which comprises a bottle main body and a bottom cover which are matched with each other, a pressure cuff used for extruding the limbs of a laboratory mouse is arranged in the bottle main body, a hose stretching hole used for stretching a hose is arranged at the side end of the bottom of the bottle main body, and the bottom of the bottom of the bottle main body is connected with the bottom cover. The center of the bottom cover is provided with a limb extending hole for extending the tail end of the limb of the laboratory mouse; one end of the hose is connected with the pressure cuff, and the other end of the hose is provided with an inflation balloon for providing an air source; and a pressure gauge for detecting inflation pressure is arranged on the hose. According to the device for preventing the muscle injury of the laboratory mouse, the double-opening design is adopted, the pressure sleeve band and the hose can completely extend into the bottle body, the integrity of the pressure sleeve band is guaranteed, the experimental limbs of the laboratory mouse can be completely placed in the bottle body, it is guaranteed that the experimental limbs are evenly pressed, and therefore the experimental mouse is prevented from suffering from muscle injury. And operation of testers is facilitated.

Description

Technical Field

[0001] The utility model relates to the technical field of biomedical research, and more particularly to a device for creating muscle injury in experimental mice. Background Art

[0002] Animal model establishment is to impose pathogenic factors on animals through artificial intervention to establish a disease model. By establishing the model, some human diseases can be more accurately simulated, providing strong support for the treatment of diseases.

[0003] Currently, a sleeve device is used to create a muscle injury model in experimental mice. A pressure cuff is arranged inside the sleeve. The experimental limb of the experimental mouse is placed inside the pressure cuff in the sleeve, and the experimental mouse is squeezed by pressurizing the pressure cuff to create muscle injury.

[0004] The opening position of the pressure gauge tube of the existing sleeve is relatively small, and only the rubber tube of the pressure gauge can pass through. When disassembling and assembling the pressure cuff, the rubber tube of the pressure gauge must be cut off first and then re - adhered, resulting in the integrity of the instrument being damaged. Poor adhesion easily causes air leakage in the pressure cuff, affecting the normal use of the instrument.

[0005] Moreover, there is only one opening on the existing sleeve for the experimental limb of the experimental mouse to extend in. This leads to the experimental limb not being completely embedded in the sleeve, resulting in the experimental limb not being evenly pressed. To solve this problem, two people are required to operate, which easily causes additional damage to the experimental limb, thus affecting the model establishment effect. Summary of the Utility Model

[0006] The technical problem to be solved by the utility model is to provide a device for creating muscle injury in experimental mice, which can completely pass the pressure cuff and the hose through the bottle body, avoid air leakage of the pressure cuff, and ensure uniform pressure on the experimental limb.

[0007] To solve the above - mentioned technical problems, the following technical solutions are adopted.

[0008] A device for creating muscle injury in experimental mice includes a matching bottle body and a bottom cover. A pressure cuff for squeezing the experimental limb of the experimental mouse is arranged inside the bottle body. A hose insertion hole for inserting a hose is opened at the bottom side end of the bottle body, and a limb extension hole for extending the end of the experimental limb of the experimental mouse is opened at the center of the bottom cover; one end of the hose is connected to the pressure cuff, and the other end of the hose is provided with an inflation balloon for providing a gas source; a pressure gauge for detecting the inflation pressure is arranged on the hose.

[0009] Further optimizing the technical solution, the bottle body and the bottom cover are assembled by threading.

[0010] Further optimize the technical solution, and a valve is provided on one side of the hose close to the inflation balloon.

[0011] Further optimize the technical solution, and the hose insertion hole extends to the end of the bottle body mouth of the bottle body.

[0012] Due to the adoption of the above technical solutions, the technical progress achieved by the present utility model is as follows.

[0013] A device for manufacturing muscle injury in experimental mice provided by the present utility model adopts a double-opening design, which can not only enable the pressure cuff and the hose to completely extend into the bottle body, ensuring the integrity of the pressure cuff, but also enable the experimental limb of the experimental mouse to be completely placed in the bottle body, ensuring that the experimental limb is uniformly pressed and facilitating the operation of the experimenter. Description of the Drawings

[0014] Figure 1 is a structural schematic diagram of the present utility model;

[0015] Figure 2 is a structural schematic diagram of the bottle body of the present utility model;

[0016] Figure 3 is a structural schematic diagram of the bottom cover of the present utility model.

[0017] Wherein: 1. Bottle body, 2. Pressure cuff, 3. Bottom cover, 4. Hose, 5. Pressure gauge, 6. Valve, 7. Inflation balloon, 8. Hose insertion hole, 9. Limb protrusion hole. Detailed Embodiments

[0018] The present utility model will be further described in detail below in conjunction with the drawings and specific embodiments.

[0019] A device for manufacturing muscle injury in experimental mice, in combination with Figures 1 to 3 as shown, includes a bottle body 1 and a bottom cover 3. The bottle body 1 and the bottom cover 3 are assembled by threads, and the bottle body 1 and the bottom cover 3 can be easily separated, facilitating the experiment on the experimental mouse.

[0020] A pressure cuff 2 is arranged inside the bottle body 1 to squeeze the limb of the experimental mouse to manufacture muscle injury in the experimental mouse. A hose insertion hole 8 is opened at the bottom side end of the bottle body 1 for inserting the hose 4. The hose insertion hole 8 extends to the end of the bottle body mouth of the bottle body 1. After removing the bottom cover 3, the hose can be inserted and removed through the hose insertion hole, and at the same time, it is convenient to disassemble and assemble the pressure cuff 2 without cutting the hose 4 anymore.

[0021] One end of the hose 4 is connected to the pressure cuff 2, and an inflation balloon 7 is arranged at the other end of the hose 4 to provide a gas source for the pressure cuff 2.

[0022] A pressure gauge 5 is provided on the hose 4 to detect the inflation pressure. A valve 6 is provided on one side of the hose 4 close to the inflatable balloon 7 to control whether to inflate the pressure cuff 2.

[0023] A limb extension hole 9 is provided at the center of the bottom cover 3 to extend the end of the experimental mouse's limb and create a muscle injury experiment on the experimental mouse.

[0024] When the utility model creates a muscle injury experiment on an experimental mouse, the animal limb is inserted into the pressure cuff through the opening at the top of the bottle body main body, and the end of the limb extends out through the limb extension hole. The valve is opened, and the pressure cuff is inflated by operating the inflatable balloon. The inflation pressure can be observed through the pressure gauge. During modeling, the end of the experimental limb of the experimental mouse is axially pulled through the limb extension hole to completely place the experimental limb in the sleeve, ensuring the modeling effect.

Claims

1. A device for causing muscle damage in experimental mice, characterized in that: The invention comprises a bottle body (1) and a bottom cover (3) which are matched with each other. A pressure cuff (2) for squeezing the limbs of an experimental mouse is arranged in the bottle body (1). A hose insertion hole (8) for inserting a hose (4) is provided at the bottom side of the bottle body (1). A limb extension hole (9) for extending the end of the limb of the experimental mouse is provided at the center of the bottom cover (3). One end of the hose (4) is connected to the pressure cuff (2). The other end of the hose (4) is provided with an inflatable balloon (7) for providing an air source. A pressure gauge (5) for detecting the inflation pressure is provided on the hose (4).

2. The device for causing muscle damage in experimental mice according to claim 1, characterized in that: The bottle body (1) and the bottom cover (3) are assembled via threads.

3. The device for causing muscle damage in experimental mice according to claim 1, characterized in that: A valve (6) is provided on one side of the hose (4) close to the inflatable balloon (7).

4. The device for causing muscle damage in experimental mice according to claim 1, characterized in that: The hose insertion hole (8) extends to the end of the bottle mouth of the bottle body (1).

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