Kit for detecting accurate proportioning of reagents

By using the technology of sealing and diffusing rings in the kit, the precise ratio of the sample and dilution solution is achieved, the problem of unsuitable proportions during the kit detection process is solved, and the color rendering effect and detection efficiency of the test strip are improved.

CN223015226UActive Publication Date: 2025-06-24HANGZHOU BINGUO INFORMATION TECH CO LTD
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Patent Information

Application Number
CN202422329566.0
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-09-24
Publication Date
2025-06-24
Estimated Expiration
2034-09-24

AI Technical Summary

Technical Problem

During the test kit, the ratio of the sample and the diluent is unsuitable, which affects the color rendering results of the test strips, resulting in the color rendering effect not obvious or the detection time is extended, and even the detection cannot be detected.

Method used

Design a kit for detecting the precise ratio of reagents. By combining the sealing pad and the flow-guiding retaining ring, the precise addition of samples and diluents is achieved to ensure the fluidity and color development effect of reagents on the strips.

Benefits of technology

Through precise ratio, the color rendering effect of the test strip color rendering area is improved, ensuring the accuracy and efficiency of the detection results.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model discloses a kit for detecting the accurate proportion of reagents. An inserting part comprises a containing cavity for inserting a test strip and a blocking sleeve which is arranged on the containing cavity and defines a reagent dripping groove, and the reagent dripping groove is connected with the containing cavity through a communicating hole; the proportioning component comprises a flow guide check ring which penetrates through the dropping hole and is inserted into the outer side of the blocking sleeve, a flow guide plate extending towards the reagent dropping groove is arranged on the inner wall of the flow guide check ring, and an overflow hole located in the upper side of the flow guide plate is formed in the side wall of the flow guide check ring; a sample is added into the reagent dropwise adding groove through the flow guide check ring, at the moment, the sample flows into the waste liquid storage cavity through the gap between the blocking sleeve and the flow guide plate, accurate adding of the sample is achieved, and when the liquid level of diluent reaches the overflow hole, the diluent flows outwards and is stored by the waste liquid storage cavity. At the moment, the diluent is quantitatively added, the adding amount of the sample and the diluent can be controlled, and the developing effect of the developing area of the test strip can be improved.
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Description

Technical Field

[0001] The utility model relates to the technical field of test kits, and in particular to a test kit with accurately proportioned detection reagents. Background Art

[0002] A test kit is a box used to hold chemical reagents for detecting chemical components, drug residues, virus types, etc. It is generally used in hospitals and pharmaceutical companies.

[0003] During use of the test kit, the collected sample is usually diluted in a diluent, and then the diluted reagent with the sample is dripped onto a test strip to detect the virus or drug components in the reagent.

[0004] During the test, the concentration of the sample in the diluent affects the color development result of the test strip. The test strip can only absorb a limited amount of reagent. If there is less sample and more diluent, the reagent concentration will be too low, resulting in unclear color development result. If there are too many samples and too little diluent, the reagent concentration will be too high, affecting the fluidity of the reagent on the test strip and prolonging the test time. In severe cases, the reagent cannot reach the color development area, resulting in undetectable problems.

[0005] Therefore, during the detection process, it is necessary to control the ratio of the diluent and the sample to improve the color development effect of the test strip.

[0006] Therefore, how to design a test kit that can improve the color development effect of test strips has become a technical problem that needs to be solved urgently by people in this field. Utility Model Content

[0007] In order to solve at least one of the technical problems mentioned in the background technology, the purpose of the utility model is to provide a test kit with accurately proportioned detection reagents to solve the problem of inappropriate proportion of detection reagents affecting the color development results of test strips.

[0008] In order to achieve the above purpose, the utility model provides the following technical solutions:

[0009] A kit for precise proportioning of detection reagents, comprising a lower box body and an upper box body that snaps onto the lower box body. The upper box body is provided with a dropping hole and a plugging component, which includes a receiving cavity for inserting the water-absorbing end of a test strip, and a barrier sleeve arranged on the receiving cavity and surrounding a reagent dropping groove. The reagent dropping groove is connected to the receiving cavity through a communication hole; a proportioning component, which includes a diversion retaining ring that passes through the dropping hole and is plugged outside the barrier sleeve. The inner wall of the diversion retaining ring is provided with a diversion plate extending towards the reagent dropping groove, and the side wall of the diversion retaining ring is provided with an overflow hole located above the diversion plate; a blocking piece that switches between a first state and a second state. In the first state, the blocking piece is plugged between the communication hole and the test strip and blocks the communication hole. A gap for the reagent to flow out is formed between the top wall of the barrier sleeve and the bottom wall of the diversion plate. In the second state, the top wall of the barrier sleeve abuts against the bottom wall of the diversion plate, the blocking piece is withdrawn, and the communication hole is opened; the receiving cavity includes a waste liquid storage cavity for receiving the reagent flowing out from the overflow hole and the top wall of the barrier sleeve.

[0010] Further, the plugging component includes a plugging sleeve installed on the lower box body. The inner wall of the plugging sleeve is provided with a horizontally arranged partition plate. The receiving cavity is located below the partition plate, the barrier sleeve is installed above the partition plate, and the communication hole is provided on the partition plate.

[0011] Further, the top wall of the barrier sleeve is lower than the top wall of the plugging sleeve. A retaining ring plugging groove is formed by the outer wall of the barrier sleeve, the top wall of the partition plate, and the inner wall of the plugging sleeve. The diversion retaining ring is plugged into the retaining ring plugging groove.

[0012] Further, the partition plate is provided with a flow-through hole that connects the retaining ring plugging groove to the waste liquid storage cavity.

[0013] Further, the receiving cavity further includes a test strip plugging groove separated from the waste liquid storage cavity. The test strip plugging groove is for inserting the test strip and is connected to the reagent dropping groove through the communication hole.

[0014] Further, the outer wall of the plugging sleeve is provided with an insertion port that communicates with the test strip plugging groove. The upper box body is provided with a sealing baffle that aligns with the insertion port. When the upper box body and the lower box body are snapped together, the sealing baffle is plugged into the insertion port. The bottom wall of the sealing baffle abuts against the test strip, and the side wall of the sealing baffle abuts against the side wall of the insertion port.

[0015] Further, the side wall of the plugging sleeve is provided with a second installation port that communicates with the test strip plugging groove. The lower box body is provided with a first installation port that aligns with the second installation port. The blocking piece extends through the first installation port and the second installation port in sequence and reaches the test strip plugging groove.

[0016] Further, the partition plate is provided with a positioning hole, and the bottom wall of the diversion retaining ring is provided with a positioning cap. In the first state, the positioning cap is disengaged from the positioning hole. In the second state, the positioning cap is plugged into the positioning hole.

[0017] Further, a guiding groove is provided on the inner wall of the snap ring insertion groove, and a guiding block inserted into the guiding groove is fixedly provided on the diversion snap ring. A spring is further included. One end of the spring abuts against the bottom wall of the guiding groove, and the other end of the spring abuts against the bottom wall of the guiding block.

[0018] Further, an observation window aligned with the test strip is provided on the upper box body.

[0019] Compared with the prior art, the beneficial effects of the present utility model are as follows: First, the communication hole is blocked by the blocking piece, and the sample is added to the reagent dropping groove by the diversion snap ring. At this time, the sample flows into the waste liquid storage cavity through the gap between the barrier sleeve and the diversion plate, realizing the accurate addition of the sample. In the second state, the diversion snap ring moves downward, and the diversion plate abuts against the barrier snap ring. At this time, the diluent is continuously added inward. When the liquid level of the diluent reaches the overflow hole, it flows out and is received by the waste liquid receiving cavity, realizing the quantitative addition of the diluent. Finally, the blocking piece is pulled out, and the sample and the diluent are mixed to form a reagent that is absorbed by the test strip, which can control the addition amounts of the sample and the diluent and is beneficial to improving the color development effect of the color development area of the test strip. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] Figure 1 is the overall structural schematic diagram of the present utility model;

[0021] Figure 2 is the unfolded schematic diagram of the present utility model;

[0022] Figure 3 is the first-angle sectional schematic diagram of the present utility model;

[0023] Figure 4 is the sectional view of the first state of the present utility model;

[0024] Figure 5 is the sectional view of the second state of the present utility model;

[0025] Figure 6 is the partial structural schematic diagram of the lower box body;

[0026] Figure 7 is the sectional view of the lower box body;

[0027] Figure 8 is the top view of the lower box body;

[0028] Figure 9 is the schematic diagram of the upper box body;

[0029] Figure 10 is the structural schematic diagram of the proportioning component.

[0030] In the figure: 11. Lower box body; 111. Supporting seat; 112. First installation opening; 12. Upper box body; 121. Observation window; 122. Dripping hole; 123. Sealing baffle; 2. Test strip; 3. Sealing piece; 4. Insertion component; 41. Insertion sleeve; 411. Storage cavity; 4111. Waste liquid storage cavity; 4112. Test strip insertion groove; 4113. Second installation opening; 412. Insertion cavity; 4121. Retaining ring insertion groove; 4122. Reagent dripping groove; 413. Barrier sleeve; 42. Partition board; 421. Positioning hole; 422. Communication hole; 423. Flow hole; 43. Insertion port; 44. Guide groove; 45. Spring; 5. Ratio component; 51. Flow guiding retaining ring; 52. Flow guiding plate; 53. Positioning cap; 54. Overflow hole; 55. Guide block. Detailed implementation manners

[0031] The technical solutions in the embodiments of the present utility model will be clearly and completely described below. Apparently, the described embodiments are only a part of the embodiments of the present utility model, rather than all the embodiments. All other embodiments obtained by those of ordinary skill in the art based on the embodiments of the present utility model without creative efforts shall fall within the protection scope of the present utility model.

[0032] This embodiment provides a kit for accurately proportioning a detection reagent, mainly for adjusting the proportion of a sample and a diluent to improve the color development effect of a test strip.

[0033] As Figure 1 and Figure 2 shown, the kit includes a lower box body 11 and an upper box body 12 buckled on the lower box body 11. Among them, a supporting seat 111 for placing the test strip 2 is arranged on the lower box body 11, and the supporting seat 111 protrudes upward from the bottom wall of the inner cavity of the lower box body 11 so as to upwardly support the test strip 2; an observation window 121 aligned with the test strip 2 is arranged on the upper box body 12, and the color development result of the color development area of the test strip 2 can be read through the observation window 121. Among them, a dripping hole 122 aligned with the test strip 2 is further arranged on the upper box body 12, and a reagent can be dripped onto the test strip 2 through the dripping hole 122, so as to realize the detection of a sample.

[0034] In order to control the proportion of the sample and the diluent when the reagent is dripped, in this embodiment, as Figure 2 and Figure 3As shown, a plug-in component 4 for inserting the water-absorbing end of the test strip 2 is fixedly provided on the supporting seat 111. A proportioning component 5 that switches between a first state and a second state is provided at the position of the dropping hole 122 of the upper box body 12. Among them, the proportioning component 5 is arranged opposite to the plug-in component 4. The sample and the diluent are sequentially placed into the plug-in component 4 by using the proportioning component 5. It should be noted here that the way of first placing the sample and then putting in the diluent can be adopted, or the way of first placing the diluent and then putting in the sample can also be adopted, so as to control the proportion of the sample and the diluent, and the concentration of the sample in the reagent can be controlled, so that the test strip 2 can show color in the color display area, improving the color display effect.

[0035] Specifically, in this embodiment, as Figure 6 and Figure 7 shown, the plug-in component 4 includes a plug-in sleeve 41 installed on the supporting seat 111. Among them, the axis of the plug-in sleeve 41 is vertically arranged, and an insertion port 43 for inserting the test strip 2 is provided on the side wall of the plug-in sleeve 41. It should be noted here that at this time, the insertion port 43 is aligned with the supporting seat 111, so that the test strip 2 placed on the supporting seat 111 can be inserted into the plug-in sleeve 41. Specifically, the water-absorbing end of the test strip 2 is inserted into the inner cavity of the plug-in sleeve 41.

[0036] It should be noted here that, as Figure 6 and Figure 7 shown, a horizontally arranged partition 42 is provided in the inner cavity of the plug-in sleeve 41. Among them, the partition 42 divides the inner cavity of the plug-in sleeve 41 into a storage cavity 411 and a plug-in cavity 412. Among them, the plug-in cavity 412 is located above the storage cavity 411. The storage cavity 411 includes a test strip insertion slot 4112 and a waste liquid storage cavity 4111 separated from the test strip insertion slot 4112. Among them, the water-absorbing end of the test strip 2 is inserted into the test strip insertion slot 4112. A communication hole 422 for communicating the plug-in cavity 412 with the test strip insertion slot 4112 is provided on the partition 42. A blocking sleeve 413 extending vertically upward is provided on the top wall of the partition 42. Among them, the axis of the blocking sleeve 413 is coaxial with the axis of the plug-in sleeve 41, and the top wall of the blocking sleeve 413 is lower than the top wall of the plug-in sleeve 41. Among them, the blocking sleeve 413 divides the plug-in cavity 412 into a retaining ring insertion slot 4121 and a reagent dropping slot 4122. The reagent dropping slot 4122 is communicated with the test strip insertion slot 4112 through the communication hole 422. As Figure 8 shown, a flow hole 423 for communicating the waste liquid storage cavity 4111 with the retaining ring insertion slot 4121 is also provided on the partition 42. It also includes a sealing piece 3 that is slidably connected and blocks the communication hole 422.

[0037] In this embodiment, taking the way of first dropping the sample and then dropping the diluent as an example, first use the sealing piece 3 to block the communication hole 422. As Figure 3 andFigure 4 As shown, it prevents the reagent in the reagent dropping groove 4122 from entering the test strip insertion groove 4112. At this time, the proportioning component 5 is in the Figure 4 first state as shown. The sample is dropped into the reagent dropping groove 4122 through the proportioning component 5. When the reagent dropping groove 4122 is filled with the sample, the sample overflows from the top wall of the barrier sleeve 413 to the retaining ring insertion groove 4121, and then the sample can enter the waste liquid storage cavity 4111 through the through hole 423, so as to ensure that the added quantity of the sample is at a fixed value.

[0038] In order to control the added quantity of the diluent, in this embodiment, as Figure 4 、 Figure 5 and Figure 10 shown, the proportioning component 5 includes a diversion retaining ring 51. Among them, the diversion retaining ring 51 includes a cylindrical part and a conical part. The conical part is located on the upper side, and the cylindrical part is located on the lower side, and the two are integrally formed. The inner wall of the diversion retaining ring 51 is provided with a diversion plate 52 that is inclined inward in a conical shape. The bottom end of the diversion plate 52 extends to the inside of the barrier sleeve 413. The side wall of the diversion retaining ring 51 is provided with an overflow hole 54 above the diversion plate 52. The bottom of the diversion retaining ring 51 is fixedly provided with a positioning cap 53. The partition plate 42 is provided with a positioning hole 421 that is aligned with the positioning cap 53. In the first state, as Figure 4 shown, at this time the overflow hole 54 is located outside the upper box body 12, the positioning cap 53 is out of contact with the positioning hole 421, and there is a gap between the diversion plate 52 and the top wall of the barrier sleeve 413; in the second state, as Figure 5 shown, the positioning cap 53 is inserted into the positioning hole 421, the overflow hole 54 is located in the lower box body 11, and the bottom wall of the diversion plate 52 abuts against the top wall of the barrier sleeve 413.

[0039] With the above settings, when the sample inside the reagent dropping groove 4122 overflows, the sample then flows through the gap between the bottom wall of the diversion plate 52 and the top wall of the barrier sleeve 413 into the retaining ring insertion groove 4121, and then flows through the through-hole 423 into the waste liquid storage chamber 4111. At this time, the proportioning component 5 is switched from the first state to the second state, and the diversion retaining ring 51 is pressed downward so that the positioning cap 53 is inserted into the positioning hole 421. At this time, the bottom wall of the diversion plate 52 abuts against the top wall of the barrier sleeve 413. Then, diluent is continuously added to the diversion retaining ring 51. At this time, the liquid level of the diluent gradually rises. When the liquid level rises to the position of the overflow hole 54, the excess diluent flows out from the overflow hole 54 and then flows downward along the outer wall of the diversion retaining ring 51 into the retaining ring insertion groove 4121, so that the excess diluent flows through the through-hole 423 into the waste liquid storage chamber 4111. Here, the addition amount of the diluent is determined, so that the accurate proportioning of the diluent and the sample can be achieved. Finally, the sealing piece 3 is withdrawn from the communication hole 422, and the communication hole 422 is opened. At this time, the reagent formed by the diluent and the sample in the proportioning component 5 is absorbed by the test strip 2, realizing the addition of the reagent.

[0040] For the convenience of installing the sealing piece 3, in this embodiment, as Figure 2 , Figure 3 and Figure 7 shown, the side wall of the insertion sleeve 41 is provided with a second installation opening 4113 communicating with the test strip insertion groove 4112, and the side wall of the lower box body 11 is provided with a first installation opening 112 aligned with the second installation opening 4113. Among them, the sealing piece 3 passes through the first installation opening 112 and the second installation opening 4113 and extends into the test strip insertion groove 4112. Among them, the top wall of the sealing piece 3 abuts against the bottom wall of the partition plate 42 to complete the sealing of the communication hole 422.

[0041] It should be noted here that since the test strip 2 is inserted into the test strip insertion groove 4112 through the insertion interface 43, when the reagent contacts the water-absorbing end of the test strip 2 through the communication hole 422, in order to prevent the reagent from flowing out from the insertion interface 43, in this embodiment, as Figure 3 and Figure 9 shown, the upper box body 12 is provided with a sealing baffle 123 aligned with the insertion interface 43. When the upper box body 12 is buckled on the lower box body 11, the sealing baffle 123 on the upper box body 12 is inserted into the insertion interface 43. The bottom wall of the sealing baffle 123 abuts against the test strip 2, and the side wall of the sealing baffle 123 abuts against the side wall of the insertion interface 43, thereby blocking the insertion interface 43 and preventing the reagent in the test strip insertion groove 4112 from flowing out from the insertion interface 43.

[0042] In order to ensure the stable movement of the proportioning component 5, in this embodiment, as Figure 2 and Figure 3As shown, a guiding groove 44 is provided on the side wall of the retaining ring insertion groove 4121. As Figure 10 shown, a guiding block 55 inserted into the guiding groove 44 is fixedly provided on the outer wall of the diversion retaining ring 51. A spring 45 is further included. One end of the spring 45 abuts against the bottom wall of the guiding groove 44, and the other end of the spring 45 abuts against the bottom wall of the guiding block 55. It is worth noting here that the spring 45 here is a compression spring. In the first state, the spring 45 pushes the diversion retaining ring 51 upward, so that the proportioning component 5 is in the first state. When the diversion retaining ring 51 is pressed downward, the spring 45 is compressed at this time, and the positioning cap 53 is inserted into the positioning hole 421, thereby restricting the upward rebound of the diversion retaining ring 51 under the elastic force of the spring 45, so that the diversion retaining ring 51 is kept at the position of the second state. At this time, the diversion plate 52 abuts against the top wall of the barrier sleeve 413, so that more reagents can be retained in the inner cavity formed inside the diversion retaining ring 51, leaving space for the addition of the diluent to flow out, so that the sample can be diluted.

[0043] It is worth noting here that when the bottom wall of the diversion plate 52 abuts against the top wall of the barrier sleeve 413, the sealing effect is achieved at this time, and the volume of the reagent dropping groove 4122 is enlarged in a variable direction for the storage of the diluent. At this time, during the addition of the diluent, the sample and the diluent cannot flow from between the barrier sleeve 413 and the diversion plate 52 to the retaining ring insertion groove 4121.

[0044] It is worth noting here that the bottom of the diversion plate 52 extends into the barrier sleeve 413, which can divert the added sample or diluent into the reagent dropping groove 4122, solving the problem that during the dropping of the sample, the sample directly enters the retaining ring insertion groove 4121 and flows into the waste liquid storage cavity 4111 through the circulation hole 423, facilitating the addition of the sample.

[0045] It is worth noting here that the encapsulation process of the reagent kit is as follows. First, the sealing piece 3 is sequentially passed through the first installation opening 112 and the second installation opening 4113, so that the sealing piece 3 is inserted into the test strip insertion groove 4112; then the test strip 2 is inserted into the test strip insertion groove 4112 from the insertion port 43, the cylindrical part of the proportioning component 5 is passed through the dropping hole 122 and installed on the upper box body 12, and then the upper box body 12 and the lower box body 11 are covered. At this time, the sealing baffle 123 is inserted into the position of the insertion port 43, and the sealing baffle 123 abuts against the test strip 2, thus completing the installation of the reagent kit.

[0046] It is worth noting here that in the first state, the overflow hole 54 is located outside the upper box body 12. At this time, the state of the proportioning component 5 can be observed. After the sample is added, the proportioning component 5 in the first state is pressed downward to become the second state. At this time, the overflow hole 54 sinks into the inner cavity of the upper box body 12, facilitating the subsequent added diluent to flow out from the overflow hole 54. As Figure 4As shown, at this time, the inner wall of the top wall of the socket sleeve 41 is provided with an inwardly inclined chamfer. At this time, the diluent at the overflow hole 54 can flow downward along the outer wall of the diversion retaining ring 51 and then be smoothly received into the retaining ring socket 4121, preventing the diluent from contacting the rest of the test strip 2 and further improving the color development effect of the test strip 2.

[0047] For those skilled in the art, it is obvious that the present invention is not limited to the details of the above exemplary embodiments, and the present invention can be implemented in other specific forms without departing from the spirit or basic characteristics of the present invention. Therefore, from any point of view, the embodiments should be regarded as exemplary and non-limiting. The scope of the present invention is defined by the appended claims rather than the above description. Therefore, all changes falling within the meaning and scope of the equivalent elements of the claims are intended to be embraced by the present invention.

Claims

1. A reagent kit with a precisely matched ratio of detection reagents, comprising a lower box body (11) and an upper box body (12) buckled with the lower box body (11), wherein the upper box body (12) is provided with a dripping hole (122), characterized in that: The plug-in component (4) comprises a storage cavity (411) for inserting the water absorption end of the test strip (2), a barrier sleeve (413) arranged on the storage cavity (411) and surrounding a reagent dripping groove (4122), and the reagent dripping groove (4122) is connected to the storage cavity (411) through a connecting hole (422); The proportioning component (5) comprises a flow guide ring (51) passing through the dripping hole (122) and plugged into the outside of the blocking sleeve (413); the inner wall of the flow guide ring (51) is provided with a flow guide plate (52) extending toward the reagent dripping groove (4122); and the side wall of the flow guide ring (51) is provided with an overflow hole (54) located on the upper side of the flow guide plate (52); The blocking piece (3) switches between a first state and a second state. In the first state, the blocking piece (3) is inserted between the connecting hole (422) and the test strip (2) to block the connecting hole (422), and the top wall of the blocking sleeve (413) and the bottom wall of the guide plate (52) form a gap for the reagent to flow out. In the second state, the top wall of the blocking sleeve (413) abuts against the bottom wall of the guide plate (52), the blocking piece (3) is pulled out, and the connecting hole (422) is opened; The storage chamber (411) comprises a waste liquid storage chamber (4111) for receiving reagents flowing out of the overflow hole (54) and the top wall of the blocking sleeve (413).

2. A kit with a precise ratio of detection reagents according to claim 1, characterized in that: The plug-in component (4) comprises a plug-in sleeve (41) mounted on the lower box body (11); a transverse partition (42) is provided on the inner wall of the plug-in sleeve (41); the storage cavity (411) is located below the partition (42); the blocking sleeve (413) is mounted above the partition (42); and the communication hole (422) is provided on the partition (42).

3. A kit with a precise ratio of detection reagents according to claim 2, characterized in that: The top wall of the blocking sleeve (413) is lower than the top wall of the plug-in sleeve (41); the outer wall of the blocking sleeve (413), the top wall of the partition (42) and the inner wall of the plug-in sleeve (41) form a retaining ring plug-in groove (4121); and the guide retaining ring (51) is plugged into the retaining ring plug-in groove (4121).

4. A kit with a precise ratio of detection reagents according to claim 3, characterized in that: The partition plate (42) is provided with a flow hole (423) for connecting the retaining ring insertion groove (4121) with the waste liquid storage chamber (4111).

5. A kit with a precise ratio of detection reagents according to claim 3, characterized in that: The storage chamber (411) further comprises a test paper insertion slot (4112) separated from the waste liquid storage chamber (4111); the test paper insertion slot (4112) is for inserting the test paper strip (2) and is connected to the reagent dripping slot (4122) through the connecting hole (422).

6. A kit with a precise ratio of detection reagents according to claim 5, characterized in that: The outer wall of the plug-in sleeve (41) is provided with an insertion port (43) which is in communication with the test paper insertion groove (4112); the upper box body (12) is provided with a sealing plate (123) which is aligned with the insertion port (43); when the upper box body (12) and the lower box body (11) are buckled together, the sealing plate (123) is inserted into the insertion port (43), the bottom wall of the sealing plate (123) abuts against the test paper strip (2), and the side wall of the sealing plate (123) abuts against the side wall of the insertion port (43).

7. A kit with a precise ratio of detection reagents according to claim 5, characterized in that: A second mounting opening (4113) communicating with the test paper insertion slot (4112) is provided on the side wall of the plug-in sleeve (41), a first mounting opening (112) aligned with the second mounting opening (4113) is provided on the lower box body (11), and the sealing piece (3) sequentially passes through the first mounting opening (112) and the second mounting opening (4113) and extends into the test paper insertion slot (4112).

8. A kit with a precise ratio of detection reagents according to claim 3, characterized in that: A positioning hole (421) is provided on the partition (42), and a positioning cap (53) is provided on the bottom wall of the guide retaining ring (51). In a first state, the positioning cap (53) is separated from the positioning hole (421), and in a second state, the positioning cap (53) is inserted into the positioning hole (421).

9. A kit with a precisely matched ratio of detection reagents according to claim 3 or 8, characterized in that: The inner wall of the retaining ring insertion groove (4121) is provided with a guide groove (44), and the guide retaining ring (51) is fixedly provided with a guide block (55) inserted into the guide groove (44), and also includes a spring (45), one end of the spring (45) abuts against the bottom wall of the guide groove (44), and the other end of the spring (45) abuts against the bottom wall of the guide block (55).

10. A kit with a precise ratio of detection reagents according to claim 1, characterized in that: The upper box body (12) is provided with an observation window (121) aligned with the test strip (2).