Honeycomb type automatic incubator
By introducing robotic arms and mobile robots into the cell culture device for automated operations, and setting up disinfection parts in the docking area for disinfection treatment, the risk of cell contamination and quality reduction caused by excessive manual operations of traditional cell culture devices is solved, and a more efficient and safer cell culture process is achieved.
Patent Information
- Application Number
- CN202422054942.X
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-08-23
- Publication Date
- 2025-06-27
- Estimated Expiration
- 2034-08-23
AI Technical Summary
There is a problem of excessive manual operation when using traditional cell culture devices, which increases the risk of cell contamination, reduces cell quality, and is not conducive to promotion and use.
A honeycomb automatic incubator was designed, using robotic arms and mobile robots for automated cell culture, and a disinfection department was set up in the docking area for disinfection treatment to reduce the risk of cell contamination.
Through automated operations, the risk of cell contamination is reduced, cell quality is guaranteed, cell culture efficiency and safety are improved, and it is conducive to promotion and use.
Smart Images

Figure CN223033394U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the technical field of cell culture equipment, and particularly relates to a honeycomb type automatic incubator. Background Art
[0002] Cell incubators are applicable to research in a wide range of fields such as cell biology, oncology, genetics, immunology, virus research cytology, and modern genetic engineering research. They are ideal devices for cell, tissue, and bacteria culture in scientific research units and industrial production departments such as modern medicine, the pharmaceutical industry, biochemistry, and agricultural science. This product is applicable to research in a wide range of fields such as cell biology, oncology, genetics, immunology, virus research cytology, and modern genetic engineering research. It is an ideal device for cell, tissue, and bacteria culture in scientific research units and industrial production departments such as modern medicine, the pharmaceutical industry, biochemistry, and agricultural science;
[0003] However, the traditional device still has the following problems in use: The entire process of cell culture is manually operated, but manual operation greatly increases the risk of cell contamination, reduces the quality of cells, and is not conducive to popularization and use. Content of the Utility Model
[0004] In view of the defects in the prior art, the utility model provides a honeycomb type automatic incubator, which reduces the risk of cell contamination, ensures the quality of cells, and is conducive to popularization and use by performing automated cell culture.
[0005] To achieve the above object, the utility model adopts the following technical solutions:
[0006] A honeycomb type automatic incubator includes an incubator body and a culture chamber. An electric sealing door is arranged on the outer wall of the incubator body; a first mobile robot is arranged at the bottom of the incubator body;
[0007] A partition is arranged in the culture chamber, and the partition divides the culture chamber into a buffer area, a consumable area, and a culture area; There are several incubator bodies, and the incubator bodies are arranged in an array in sequence in the buffer area;
[0008] A robotic arm is arranged in the culture area, and a second mobile robot is arranged at the bottom of the robotic arm;
[0009] Docking areas are arranged at both ends of the culture chamber, and a disinfection part is arranged in the docking area. The disinfection part includes a front automatic door, a rear automatic door, a supply main pipe, a disinfection pipe, an atomizing nozzle, a drying frame, and a cold air blower. The front automatic door and the rear automatic door are respectively arranged at the front and rear ends of the docking area;
[0010] The upper end of the inner wall of the docking area is provided with the main supply pipe, the outer wall of the main supply pipe is arrayed with the disinfection pipes, and the lower end of the disinfection pipe is provided with the atomizing nozzles.
[0011] The side of the docking area is provided with the air drying frame, the air cooler is arranged inside the air drying frame, and the air cooling ports are arranged on the outer wall of the air drying frame.
[0012] As an improved technical solution, a limiting plate is arranged on the side of the buffer area, and an infrared sensing area is arranged on the outer wall of the limiting plate.
[0013] As an improved technical solution, an auxiliary power supply is arranged in the consumable area, a power indicator is arranged at the front end of the auxiliary power supply, and a charging socket is arranged on the side of the auxiliary power supply.
[0014] As an improved technical solution, there are two manipulators, which are respectively arranged in different areas of the culture chamber; there are two second mobile robots, and the second mobile robots and the manipulators are arranged in a one-to-one correspondence.
[0015] As an improved technical solution, a disinfection barrel is arranged on the outer wall of the docking area, a pressure pump is arranged on the outer wall of the disinfection barrel, a delivery pipe is arranged at the output end of the pressure pump, and the end of the delivery pipe is connected to the main supply pipe.
[0016] As an improved technical solution, a liquid level gauge is arranged inside the disinfection barrel, a control panel is arranged on the outer wall of the disinfection barrel, a buzzer is arranged on the side of the control panel, and the control panel is respectively connected to the liquid level gauge and the buzzer.
[0017] As an improved technical solution, a fan filter unit is arranged at the upper end of the culture chamber.
[0018] As an improved technical solution, maintenance doors are arranged on the outer wall of the culture chamber, there are two maintenance doors, and the maintenance doors are respectively arranged on two opposite sides of the culture chamber.
[0019] Due to the above technical solutions, the present utility model has the following beneficial effects:
[0020] 1. For this honeycomb type automatic incubator, through the arrangement of the manipulator and the mobile robot for automatic cell culture, and at the same time through the arrangement of the docking area for disinfection treatment, the risk of cell contamination can be reduced, which is conducive to popularization and use.
[0021] 2. For this honeycomb type automatic incubator, through the arrangement of the infrared sensing area, it is beneficial to limit the position of the incubator body, which is beneficial to the intensive placement of the incubator body.
[0022] 3. The honeycomb automatic incubator is provided with the auxiliary power supply to ensure the normal use of the culture chamber in case of power failure.
[0023] 4. The honeycomb automatic incubator is provided with two manipulators to facilitate the simultaneous operation of different incubator bodies, improving the efficiency of cell culture.
[0024] 5. The honeycomb automatic incubator is provided with the disinfection barrel to ensure the normal supply of the disinfectant solution, facilitating the disinfection operation. Description of the Drawings
[0025] In order to more clearly illustrate the specific embodiments of the present invention or the technical solutions in the prior art, the following will briefly introduce the drawings required for the description of the specific embodiments or the prior art. In all the drawings, similar elements or parts are generally identified by similar reference numerals. In the drawings, the elements or parts are not necessarily drawn to scale.
[0026] Figure 1 It is a front view of a honeycomb automatic incubator;
[0027] Figure 2 It is a top view of a honeycomb automatic incubator;
[0028] Figure 3 It is a schematic structural diagram of the culture chamber;
[0029] Figure 4 It is a schematic structural diagram of the disinfection part;
[0030] Figure 5 It is a schematic structural diagram of the auxiliary power supply.
[0031] In the drawings, 1. Incubator body, 2. Electrically sealed door, 3. Culture chamber, 31. Buffer area, 311. Limiting plate, 312. Infrared induction area, 32. Consumable area, 321. Auxiliary power supply, 322. Power indicator light, 323. Charging socket, 33. Culture area, 34. Fan filter unit, 35. Maintenance door, 4. First mobile robot, 5. Partition board, 6. Manipulator, 61. Second mobile robot, 7. Docking area, 8. Disinfection part, 81. Front automatic door, 82. Rear automatic door, 83. Supply main pipe, 84. Disinfection pipe, 85. Atomizing nozzle, 86. Air drying frame, 861. Air cooling port, 87. Cold air blower, 9. Disinfection barrel, 91. Pressure pump, 92. Delivery pipe, 93. Liquid level gauge, 94. Control screen, 95. Buzzer. Detailed Embodiments
[0032] The technical solution of the present utility model will be described in detail below in conjunction with specific embodiments. The following embodiments are only used to more clearly illustrate the technical solution of the present utility model, so they are only examples and cannot be used to limit the protection scope of the present utility model.
[0033] As Figures 1-5 shown, the present utility model provides a honeycomb type automatic incubator, which includes an incubator body 1 and a culture chamber 3. A fan filter unit 34 is arranged at the upper end of the culture chamber 3, and the above-mentioned fan filter unit 34 adopts an FFU high-efficiency filter;
[0034] The FFU high-efficiency filter is a combination of a fan and a filter, and can also be called a "filter device with a built-in fan". The FFU is usually installed at the air supply end of a clean room;
[0035] The FFU is an independent and self-contained air purification device, usually installed on the ceiling or under the workbench; it includes a fan, a high-efficiency filter and an air outlet. The fan sucks air in and purifies it through the filter, and then evenly discharges the clean air to the working area to form a clean environment;
[0036] An electric sealing door 2 is arranged on the outer wall of the incubator body 1, and the electric sealing door 2 facilitates automatic opening operation;
[0037] A first mobile robot 4 is arranged at the bottom of the incubator body 1, and the first mobile robot 4 drives the incubator body 1 to move;
[0038] A partition 5 is arranged in the culture chamber 3, and the partition 5 divides the culture chamber 3 into a buffer area 31, a consumable area 32 and a culture area 33. The buffer area 31 is conducive to the placement of the incubator body 1, the consumable area 32 is used to place the consumables for culture, and the culture area 33 is used for cell culture operations;
[0039] There are several incubator bodies 1, and the incubator bodies 1 are arranged in an array in the buffer area 31 in sequence; arranging several incubator bodies 1 facilitates honeycomb type automatic culture;
[0040] A limiting plate 311 is arranged on the side of the buffer area 31, and an infrared sensing area 312 is arranged on the outer wall of the limiting plate 311; arranging the infrared sensing area 312 is conducive to limiting the position of the incubator body 1 and facilitating the intensive placement of the incubator body 1;
[0041] A robotic arm 6 is arranged in the culture area 33, and a second mobile robot 61 is arranged at the bottom of the robotic arm 6; the entire cell culture operation is completed by the robotic arm 6, avoiding manual operation and effectively preventing cell infection;
[0042] There are two robotic arms 6, which are respectively arranged in different areas of the culture chamber 3; there are two second mobile robots 61, and the second mobile robots 61 and the robotic arms 6 are arranged in a one-to-one correspondence; arranging two robotic arms 6 facilitates the simultaneous operation of different incubator bodies 1 and improves the efficiency of cell culture;
[0043] The normal process of setting up the cell culture area 33 is: liquid change, subculture, separation, observation, inoculation, collection and plating, which can complete the cell culture operation;
[0044] Docking areas 7 are arranged at both ends of the culture chamber 3. Through the docking areas 7 for docking, disinfection operations are first carried out to effectively sterilize;
[0045] A disinfection part 8 is arranged in the docking area 7. The disinfection part 8 includes a front automatic door 81, a rear automatic door 82, a supply main pipe 83, a disinfection pipe 84, an atomizing nozzle 85, a drying frame 86 and a cold air blower 87. The front automatic door 81 and the rear automatic door 82 are respectively arranged at the front and rear ends of the docking area 7;
[0046] The supply main pipe 83 is arranged at the upper end of the inner wall of the docking area 7. The outer wall of the supply main pipe 83 is provided with a disinfection pipe 84 in an array, and the atomizing nozzle 85 is arranged at the lower end of the disinfection pipe 84;
[0047] The drying frame 86 is arranged on the side of the docking area 7. The cold air blower 87 is arranged in the drying frame 86, and an air cooling port 861 is arranged on the outer wall of the drying frame 86;
[0048] A disinfection bucket 9 is arranged on the outer wall of the docking area 7. A pressure pump 91 is arranged on the outer wall of the disinfection bucket 9. The output end of the pressure pump 91 is provided with a delivery pipe 92, and the end of the delivery pipe 92 is connected to the supply main pipe 83; arranging the disinfection bucket 9 ensures the normal supply of the disinfectant liquid and is conducive to carrying out disinfection operations;
[0049] A liquid level gauge 93 is arranged inside the disinfection bucket 9. A control panel 94 is arranged on the outer wall of the disinfection bucket 9. A buzzer 95 is arranged on the side of the control panel 94. The control panel 94 is respectively connected to the liquid level gauge 93 and the buzzer 95;
[0050] An auxiliary power supply 321 is arranged in the consumable area 32. A power indicator light 322 is arranged at the front end of the auxiliary power supply 321. A charging socket 323 is arranged on the side of the auxiliary power supply 321; arranging the auxiliary power supply 321 facilitates ensuring the normal use of the culture chamber 3 in case of a power outage accident;
[0051] Maintenance doors 35 are arranged on the outer wall of the culture chamber 3. There are two maintenance doors 35, and the maintenance doors 35 are respectively arranged on two opposite sides of the culture chamber 3; arranging the maintenance doors 35 to carry out
[0052] The steps of the above honeycomb automatic culture are as follows:
[0053] Start the front automatic door 81 of the front docking area 7, move the incubator body 1 into the docking area 7, close the front automatic door 81, and the incubator body 1 is moved to the lower part of the atomizing nozzle 85 by the first mobile robot 4 for disinfection and sterilization operations;
[0054] To ensure the normal supply of the disinfectant, the liquid level gauge 93 detects the amount of the disinfectant. When the disinfectant is lower than the set normal value, the buzzer 95 starts to work to remind people and facilitate the timely addition of the disinfectant;
[0055] Start the pressure pump 91. The output end of the pressure pump 91 drives the disinfectant in the disinfection bucket 9 into the delivery pipe 92 and enters the main supply pipe 83 through the delivery pipe 92; the disinfectant enters the atomizing nozzle 85 through the main supply pipe 83 and the disinfection pipe 84, and the incubator body 1 is completely disinfected through the atomizing nozzle 85;
[0056] After disinfection, start the cold air blower 87. The wind generated by the cold air blower 87 performs air-cooling operation on the incubator body 1 through the air-cooling port 861;
[0057] After the operation is completed, open the rear automatic door 82, and the incubator body 1 is moved into the buffer area 31 by the first mobile robot 4; repeat the above operations until all the incubator bodies 1 are placed;
[0058] After the incubator body 1 is sent to the buffer area 31, start the second mobile robot 61. The second mobile robot 61 drives the robotic arm 6 to move in front of the incubator body 1, and start the robotic arm 6 to drive the cell culture dish to start the whole process, specifically including liquid change, passage, separation, observation, inoculation, collection and plating to complete the cell culture operation;
[0059] After the cell culture is completed, start the front automatic door 81 of the rear docking area 7, and the docking equipment enters for disinfection to facilitate docking with the cells that have completed the culture.
[0060] Finally, it should be noted that: the above embodiments are only used to illustrate the technical solutions of the present invention, rather than limiting it; although the present invention has been described in detail with reference to the foregoing embodiments, those of ordinary skill in the art should understand that: they can still modify the technical solutions recorded in the foregoing embodiments, or perform equivalent replacements on some or all of the technical features; and these modifications or replacements do not make the essence of the corresponding technical solutions deviate from the scope of the technical solutions of the embodiments of the present invention, and they should all be covered by the scope of the claims and the description of the present invention.
Claims
1. A honeycomb automatic incubator, characterized in that: It comprises an incubator body and a culture chamber, wherein an electric sealing door is arranged on the outer wall of the incubator body; and a first mobile robot is arranged at the bottom of the incubator body; The culture chamber is provided with a partition, and the partition divides the culture chamber into a buffer area, a consumable area and a culture area; the culture box body is provided with a plurality of culture box bodies, and the culture box bodies are arranged in the buffer area in an array in sequence; A mechanical arm is arranged in the culture area, and a second mobile robot is arranged at the bottom of the mechanical arm; Both ends of the culture room are provided with docking areas, and a disinfection part is provided in the docking area. The disinfection part includes a front automatic door, a rear automatic door, a supply main pipe, a disinfection pipe, an atomizing nozzle, an air drying frame and a cold air blower. The front and rear ends of the docking area are respectively provided with the front automatic door and the rear automatic door; The supply main pipe is arranged at the upper end of the inner wall of the docking area, the disinfection pipe is arranged in an array on the outer wall of the supply main pipe, and the atomizing nozzle is arranged at the lower end of the disinfection pipe; The air drying frame is arranged at the side of the docking area, the air cooler is arranged in the air drying frame, and the outer wall of the air drying frame is arranged with an air cooling port.
2. A honeycomb automatic incubator according to claim 1, characterized in that: A limiting plate is arranged on the side of the buffer area, and an infrared sensing area is arranged on the outer wall of the limiting plate.
3. The honeycomb automatic incubator according to claim 1, characterized in that: An auxiliary power supply is arranged in the consumable area, a power indicator light is arranged at the front end of the auxiliary power supply, and a charging socket is arranged at the side of the auxiliary power supply.
4. The honeycomb automatic incubator according to claim 1, characterized in that: There are two robotic arms, which are respectively arranged in different areas of the culture chamber; there are two second mobile robots, which are arranged opposite to the robotic arms one by one.
5. The honeycomb automatic incubator according to claim 1, characterized in that: A sterilizing barrel is arranged on the outer wall of the docking area, a pressure pump is arranged on the outer wall of the sterilizing barrel, a delivery pipe is arranged at the output end of the pressure pump, and an end of the delivery pipe is connected to the supply main pipe.
6. A honeycomb automatic incubator according to claim 5, characterized in that: A liquid level meter is arranged inside the disinfection barrel, a control panel is arranged on the outer wall of the disinfection barrel, a buzzer is arranged on the side of the control panel, and the control panel is connected to the liquid level meter and the buzzer respectively.
7. The honeycomb automatic incubator according to claim 1, characterized in that: A fan filter unit is arranged at the upper end of the culture chamber.
8. The honeycomb automatic incubator according to claim 1, characterized in that: An inspection door is arranged on the outer wall of the culture chamber, and two inspection doors are arranged, and the inspection doors are arranged on two opposite sides of the culture chamber respectively.