Precise sample adding device for providing IVD (Intrinsic Vapor Deposition) analyzer
By designing a precision sample replenishing device including a servo motor-driven syringe and a ball screw, the problem of insufficient accuracy and repeatability accuracy of the existing IVD analyzer sample replenishing device is solved, and the sample replenishing effect with high accuracy and high repeatability accuracy is achieved, and the accuracy of the test results is improved.
Patent Information
- Application Number
- CN202421873192.2
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-08-05
- Publication Date
- 2025-06-27
- Estimated Expiration
- 2034-08-05
AI Technical Summary
The sample loading device of the existing IVD analyzer has insufficient accuracy and repeatability accuracy due to the drive error of the screw stepper motor, insufficient sealing between the plunger and the pump chamber, and the back gap between the screw stepper motor and the plunger rod, which affects the accuracy of the test results.
A precision sample replenishing device including a frame, a syringe, a driving mechanism, a ball screw, a connecting device and a control mechanism is designed. The syringe movement is driven by a servo motor, and the ball screw is used to eliminate the back gap between the syringe and the ball screw, and improve the sample replenishing accuracy and repeatability accuracy.
The high accuracy and high repeatability accuracy of sample addition are achieved, the accuracy of IVD analyzer test results is improved, the dependence on the control algorithm is reduced, and the cost is reduced.
Smart Images

Figure CN223037962U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the technical field of analyzers, and specifically provides a precise sample adding device for an IVD analyzer. Background Art
[0002] An IVD (In Vitro Diagnostics) analyzer is a product that obtains clinical diagnostic information by detecting human samples (such as blood, body fluids, tissues, etc.) outside the human body. It plays an important role in disease prevention, diagnosis, treatment monitoring, health assessment, etc.
[0003] The sample adding device of the existing IVD analyzer usually uses a plunger pump to complete sample addition; the plunger pump mainly consists of a pump body, a motor, a plunger, a plunger rod, a valve, etc. The plunger pump uses the motor to drive the plunger to reciprocate in the pump cavity, thereby generating a pressure difference to complete the actions of sucking and discharging samples. In the suction stage, the motor drives the plunger to move backward, a negative pressure is formed in the pump cavity, and the liquid is sucked into the pump cavity; in the discharge stage, the motor drives the plunger to move forward, a positive pressure is formed in the pump cavity, and the liquid is discharged from the pump cavity.
[0004] The existing technology has the following defects:
[0005] 1. The existing plunger pumps generally use a lead screw stepping motor to drive, and the backlash of the lead screw stepping motor nut is relatively large, resulting in errors in the stroke when driving the plunger, thus leading to insufficient accuracy in sample addition;
[0006] 2. The sealing performance between the plunger and the pump cavity will also lead to insufficient accuracy in sample addition;
[0007] 3. At the same time, the backlash in the connection between the lead screw stepping motor and the plunger rod will lead to insufficient repeatability accuracy (CV) in sample suction and discharge;
[0008] 4. The existing plunger pumps need to design corresponding control algorithms to control their use;
[0009] Insufficient accuracy and repeatability accuracy in sample suction and discharge will lead to insufficient accuracy of the test results of the biochemical analyzer, affecting the test performance of the analyzer. Content of the Utility Model
[0010] The purpose of the utility model is to overcome the problems proposed in the above background art, and provides a precise sample adding device for an IVD analyzer. This sample adding device can meet the accuracy requirements when adding trace amounts of reagents and samples during the test process of the IVD analyzer; improve the repeatability accuracy CV of the added sample volume during sample addition.
[0011] The purpose of the utility model is mainly achieved through the following technical solutions:
[0012] A precision sample addition device for an IVD analyzer, comprising a frame. A syringe, a driving mechanism, a ball screw, a connecting device and a control mechanism are arranged on the frame. The control mechanism is connected to the driving mechanism. The ball screw is connected to the driving mechanism and can rotate around its own axis. The connecting device is connected to the ball screw and can perform linear motion when the ball screw rotates. The syringe is connected to the connecting device. Currently, the sample addition device usually uses a plunger pump to complete sample addition. The plunger pump mainly consists of a pump body, a motor, a plunger, a plunger rod, a valve, etc. The plunger pump uses the motor to drive the plunger to reciprocate in the pump cavity, thereby generating a pressure difference to complete the actions of sucking and discharging samples. In the suction stage, the motor drives the plunger to move backward, a negative pressure is formed in the pump cavity, and the liquid is sucked into the pump cavity. In the discharge stage, the motor drives the plunger to move forward, a positive pressure is formed in the pump cavity, and the liquid is discharged from the pump cavity. In this structure, since the existing plunger pump generally uses a screw stepper motor for driving, the backlash of the screw stepper motor nut is relatively large, resulting in errors in the stroke when driving the plunger, thus leading to insufficient accuracy in sample addition. Moreover, the sealing between the plunger and the pump cavity also causes insufficient accuracy in sample addition. At the same time, the backlash between the screw stepper motor and the plunger rod results in insufficient repeatability accuracy (CV) in sucking and discharging samples. In addition, the existing plunger pump needs to design a corresponding control algorithm for control, increasing the cost. The insufficient accuracy and repeatability accuracy in sucking and discharging samples will lead to insufficient accuracy of the test results of the biochemical analyzer, affecting the test performance of the analyzer. To solve the above problems, this solution designs a precision sample addition device for an IVD analyzer, comprising a frame. The frame is a support and installation component of the overall structure. A syringe, a driving mechanism, a ball screw, a connecting device and a control mechanism are arranged on the frame. The control mechanism is connected to the driving mechanism. The control mechanism is an existing component, connected to the driving mechanism through a cable, and is used to control the actions of the driving motor. The driving mechanism is preferably a motor. The ball screw is connected to the driving mechanism and can rotate around its own axis. The connecting device is connected to the ball screw and can perform linear motion when the ball screw rotates. The syringe is connected to the connecting device. The way the motor drives the syringe - converts the rotational motion of the motor into the linear motion of the syringe piston through rolling friction to complete the actions of sucking and discharging liquid. The assembly precision between the mechanisms is the basis for ensuring the precise motion of the syringe piston. The higher the precision of the syringe piston motion, the higher the sample addition precision of the sample addition system. It can directly recognize external instructions without designing a corresponding control algorithm. The control mechanism adopts servo control and can process external instructions into corresponding control action commands for the servo motor. The connection method between the syringe and the ball screw: eliminates the backlash between the syringe and the ball screw through the connecting device, improves the motion repeatability accuracy of the syringe, ensures the position consistency of each motion, and improves the sample addition repeatability accuracy of the sample addition system.
[0013] Further, a guiding groove is provided on the frame, and the connecting device passes through the guiding groove and can move in the guiding groove. By providing the guiding groove, the moving track of the connecting device is defined, and at the same time, it also plays a guiding role, making the movement smoother.
[0014] Further, a nut seat is sleeved on the ball screw, and the connecting device is connected to the nut seat. The nut seat and the ball screw cooperate to form a ball screw nut pair, which can convert the rotation of the motor into a linear motion of the connecting device, so as to drive the action of the syringe. And connecting the piston rod of the syringe to the connecting device makes the connection between them tight and the action is realized in place.
[0015] Further, a bearing seat is provided on the frame, and the ball screw is connected to the bearing seat and can rotate in the bearing seat. Through the bearing seat, the support of the ball screw is realized, and its rotation function is also realized.
[0016] Further, a sensor is provided on the frame. The real-time position of the mechanism is detected by the sensor to ensure the accuracy of the movement position of the mechanism, and the accuracy of sample aspiration and discharge can be improved.
[0017] In summary, the present utility model has the following beneficial effects compared with the prior art:
[0018] (1) The present utility model drives the syringe to move through the motor - converts the rotational motion of the motor into a linear motion of the syringe piston through rolling friction to complete the action of sucking and discharging liquid;
[0019] (2) The assembly precision between the mechanisms of the present utility model is the basis for ensuring the precise movement of the syringe piston. The higher the precision of the movement of the syringe piston, the higher the precision of sample addition of the sample addition system;
[0020] (3) The present utility model can directly recognize external instructions without designing corresponding control algorithms: the servo control mechanism can process external instructions into action commands for controlling the servo motor;
[0021] (4) The present utility model detects the real-time position of the mechanism through the sensor to ensure the accuracy of the movement position of the mechanism, and the accuracy of sample aspiration and discharge can be improved;
[0022] (5) The present utility model eliminates the backlash between the syringe and the ball screw through the connecting device, improves the movement repeatability accuracy of the syringe, ensures the position consistency of each movement, and improves the sample addition repeatability accuracy of the sample addition system. Description of the Drawings
[0023] The drawings described herein are used to provide a further understanding of the embodiments of the present utility model, form a part of this application, and do not limit the embodiments of the present utility model. In the drawings:
[0024] Figure 1 This is a three-dimensional structural schematic diagram of the present utility model.
[0025] Figure 2 This is a cross-sectional view of the present utility model.
[0026] The names corresponding to the reference numerals in the drawings are as follows:
[0027] 1 - Frame, 2 - Syringe, 3 - Driving mechanism, 4 - Control mechanism, 5 - Ball screw, 6 - Connecting device, 7 - Nut seat, 8 - Guide groove, 9 - Bearing seat. Specific embodiments
[0028] Next, the technical solutions in the embodiments of the present utility model will be clearly and completely described in conjunction with the accompanying drawings in the embodiments of the present utility model. Obviously, the described embodiments are only a part of the embodiments of the present utility model, rather than all the embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without making creative efforts shall fall within the protection scope of the present utility model.
[0029] In the description of the present utility model, it should be understood that the orientation or positional relationship indicated by orientation words such as "front, rear, upper, lower, left, right", "lateral, vertical, perpendicular, horizontal" and "top, bottom" is usually based on the orientation or positional relationship shown in the drawings, and is only for the convenience of describing the present utility model and simplifying the description. Without contrary explanations, these orientation words do not indicate and imply that the device or element referred to must have a specific orientation or be constructed and operated in a specific orientation, and thus cannot be understood as limiting the protection scope of the present utility model; the orientation words "inside, outside" refer to the inside and outside relative to the contour of each component itself.
[0030] In addition, it should be noted that the use of words such as "first", "second" to limit components is only for the convenience of distinguishing the corresponding components. Without otherwise stating, the above words have no special meanings, and thus cannot be understood as limiting the protection scope of the present utility model.
[0031] Such as Figure 1 And Figure 2As shown in the figure, a precise sample addition device for an IVD analyzer in this embodiment is provided with a frame 1. The frame 1 is a support and installation component of the overall structure. A syringe 2, a driving mechanism 3, a ball screw 5, a connecting device 6, and a control mechanism 4 are arranged on the frame 1. The driving mechanism 3 uses a servo motor. The servo motor, the control mechanism 4, and the syringe 2 are all fixed on the frame 1. The control mechanism 4 is connected to the servo motor through a cable. Among them, the syringe 2 is fixed on the outside of the frame 1. A bearing seat 9 is arranged on the frame 1. The ball screw 5 is installed on the bearing seat 9 and is connected to the servo motor at one end. In this way, both the support of the ball screw 5 and its rotation function are realized.
[0032] A nut seat 7 is sleeved on the ball screw 5, and the connecting device 6 is connected to the nut seat 7. A ball screw nut is arranged inside the nut seat 7, which can match with the ball screw 5. In this way, they are combined to form a ball screw nut pair, which can convert the rotation of the servo motor into the linear motion of the connecting device, and thus drive the action of the syringe.
[0033] The piston rod of the syringe 2 is connected to the connecting device 6. A guide groove 8 is arranged on the frame 1. The connecting device 6 passes through the guide groove 8 and can move in the guide groove 8. By setting the guide groove 8, the moving track of the connecting device 6 is limited, and at the same time, it also plays a guiding role, making the movement smoother.
[0034] A sensor is arranged on the frame 1, which can monitor the positions of the piston rod and the connecting device 6 in real time.
[0035] Working principle: When the precise sample addition device is working, an instruction to aspirate and discharge a specified volume of reagent / sample is input into the control mechanism 4. The control mechanism 4 is converted into a control instruction to control the rotation of the servo motor. When the servo motor rotates, it drives the ball screw 5 to rotate. The nut seat 7 converts the rotational motion of the ball screw 5 into a linear motion. At the same time, the nut seat 7 is connected to the connecting device 6, and through the guide groove 8 on the frame 1 for guiding, it drives the piston rod of the syringe 2 to do a linear motion. The syringe piston makes a reciprocating motion in the syringe inner cavity, so that negative pressure or positive pressure is formed inside the syringe, and the action of sucking and discharging liquid is completed.
[0036] The controllable precision of the servo motor is much higher than that of the stepper motor. The matching precision between the ball screw 5 and the nut seat 7 is much higher than that of the motor screw nut. The sealing condition of the syringe is much better than that of the plunger and the pump cavity. Therefore, the servo motor provides power, the ball screw provides high-precision positioning, the frame is responsible for high-precision guiding, and the sensor monitors the operation of the syringe in real time, jointly driving the syringe to complete the high-precision and high-repeatability sample addition action.
[0037] The content not described in detail in this specification belongs to the prior art well-known to those skilled in the art. The standard parts used in this utility model can all be purchased from the market. The special-shaped parts can all be customized according to the description in the specification and the drawings. The specific connection methods of each part all adopt conventional means such as bolts, rivets, and welding that are mature in the prior art. The machinery, parts, and equipment all adopt conventional models in the prior art. Coupled with the circuit connection adopting the conventional connection method in the prior art, details are not described herein again.
[0038] Although the embodiments of the present utility model have been shown and described, for those of ordinary skill in the art, it can be understood that various changes, modifications, substitutions, and variations can be made to these embodiments without departing from the principle and spirit of the present utility model. The scope of the present utility model is defined by the appended claims and their equivalents.
Claims
1. A precision sample adding device for an IVD analyzer, characterized in that: The invention comprises a frame (1), on which a syringe (2), a driving mechanism (3), a ball screw (5), a connecting device (6) and a control mechanism (4) are arranged, the control mechanism (4) is connected to the driving mechanism (3), the ball screw (5) is connected to the driving mechanism (3) and can rotate around its own axis, the connecting device (6) is connected to the ball screw (5) and can perform linear motion when the ball screw (5) rotates, and the syringe (2) is connected to the connecting device (6).
2. A precision sample adding device for an IVD analyzer according to claim 1, characterized in that: The frame (1) is provided with a guide groove (8), and the connecting device (6) passes through the guide groove (8) and is capable of moving in the guide groove (8).
3. The precise sample adding device for providing an IVD analyzer according to claim 1, characterized in that: The ball screw (5) is sleeved with a nut seat (7), and the connecting device (6) is connected to the nut seat (7).
4. The precise sample adding device for providing an IVD analyzer according to claim 1, characterized in that: A bearing seat (9) is provided on the frame (1), and the ball screw (5) is connected to the bearing seat (9) and can rotate in the bearing seat (9).
5. The precise sample adding device for providing an IVD analyzer according to claim 1, characterized in that: The piston rod of the syringe (2) is connected to the connecting device (6).
6. The precise sample adding device for an IVD analyzer according to claim 1, characterized in that: The frame (1) is provided with a sensor.