Continuous production device suitable for metal amino complexes

By designing a continuous production device, the problems of low production efficiency and unstable reaction of metal amine-based complexes are solved, and efficient and stable product purification and collection are achieved.

CN223042698UActive Publication Date: 2025-07-01THE SECOND AFFILIATED HOSPITAL OF XINGTAI MEDICAL COLLEGE
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Patent Information

Application Number
CN202422226781.8
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-09-11
Publication Date
2025-07-01
Estimated Expiration
2034-09-11

AI Technical Summary

Technical Problem

The existing metal amine-based complex production devices cannot undergo continuous treatment, resulting in low production efficiency, difficult to stabilize the control of reaction conditions, and poor heat and gas discharge during the reaction, which affects the normal progress of the reaction and product collection.

Method used

A continuous production device including infusion bottles, regulating valves, temperature sensors, microfluidic pipelines, continuous reactors, dynamic reactors, filters and distillers are designed to ensure smooth progress of the reaction by controlling the reaction temperature and gas discharge, and the purification of the product is achieved through filtration and distillation.

Benefits of technology

The production efficiency of metal amine-based complexes is improved, the reaction conditions are stable, the product is purified, and the product is effectively collected and purified.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model discloses a continuous production device suitable for metal amino complexes, which particularly relates to the field of medical instruments and comprises a whole device, and an auxiliary production mechanism is mounted in the whole device. By arranging the auxiliary production mechanism, the production efficiency is improved, a required metal ion solution and other reactants are respectively filled into the infusion bottles and enter the first preparation device through the infusion bottles, in the first preparation device, raw materials of the first preparation device and the second preparation device enter the continuous reactor through the micro-flow pipeline, and a preliminary reaction is performed at the moment; continuously conveying into a dynamic reactor by a pump body for further reaction or treatment, performing further chemical reaction or physical change on the product in the dynamic reactor, discharging the gas generated in the reaction process through an exhaust pipe, collecting a liquid product by a liquid collecting bottle, and removing impurities and unreacted raw materials from the product by a filter, so as to obtain the product. The purity of the final product is ensured, and the final product enters a distiller.
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Description

Technical Field

[0001] The utility model relates to the field of medical instruments, and more specifically, the utility model relates to a continuous production device suitable for metal amine complexes. Background Technique

[0002] Metal amine complexes, as a class of compounds with unique physical and chemical properties, play an important role in drug development. These complexes can interact with metal ions (such as zinc, copper, iron, etc.) or biomolecules (such as proteins, enzymes, etc.) in organisms, affecting the normal metabolic processes of organisms, and thus exhibiting a wide range of pharmacological activities. For example, certain metal amine complexes have been proven to have biological activities such as anti-cancer, anti-bacterial, and anti-inflammatory, and have become important candidates for new drug development;

[0003] Existing devices cannot perform continuous processing, resulting in low production efficiency, and it is difficult to stably control the reaction conditions. At the same time, the heat and gas generated during the reaction may not be effectively discharged, affecting the normal progress of the reaction and the collection of products, and there are limitations in the later use process;

[0004] Therefore, a continuous production device suitable for metal amine complexes is proposed to solve the above problems. Content of the Utility Model

[0005] In order to overcome the above-mentioned defects of the prior art, the utility model provides a continuous production device suitable for metal amine complexes to solve the problems raised in the above background technique.

[0006] To achieve the above purpose, the utility model provides the following technical solution: A continuous production device suitable for metal amine complexes, including the overall device, and an auxiliary production mechanism is installed inside the overall device;

[0007] A first dispenser is installed inside the whole device. One side of the outside of the first dispenser is nested and installed on an infusion bottle. A regulating valve is nested and installed at the bottom of the infusion bottle. A temperature sensor is installed inside the first dispenser. A microfluidic pipeline is nested and installed at the bottom of the first dispenser. A second dispenser is nested and installed on one side of the microfluidic pipeline. A continuous flow reactor is nested and installed at the bottom of the microfluidic pipeline. A delivery pipe is nested and installed on one side of the continuous flow reactor. A pump body is nested and installed on the outside of the delivery pipe. Another side of the delivery pipe is nested and installed on a dynamic reactor. A third dispenser is nested and installed on one side of the top of the dynamic reactor. An exhaust pipe is nested and installed on one side of the top of the third dispenser. Another side of the exhaust pipe is nested and installed on a liquid collection bottle. A refrigeration component is embedded and installed inside the liquid collection bottle. A filter is nested and installed on one side of the dynamic reactor. A filter screen is embedded and installed inside the filter. A distiller is nested and installed on one side of the filter. A heating component is nested and installed at the bottom of the distiller.

[0008] Further, a drive machine is nested and installed at the bottom of the dynamic reactor, and a stirrer is nested and installed on the top of the drive machine.

[0009] Further, there are three infusion bottles, regulating valves and temperature sensors, which are evenly distributed inside the first dispenser, the second dispenser and the third dispenser.

[0010] Further, the pump body is installed between the continuous flow reactor and the dynamic reactor.

[0011] Further, the exhaust pipe is installed between the dynamic reactor and the liquid collection bottle.

[0012] Further, the refrigeration component and the liquid collection bottle are used in cooperation.

[0013] Further, the stirrer is installed inside the dynamic reactor.

[0014] Further, the drive machine and the stirrer are used in cooperation.

[0015] The technical effects and advantages of the present utility model:

[0016] 1. Compared with the prior art, the continuous production device applicable to metal amine complexes improves production efficiency by setting up an auxiliary production mechanism. The required metal ion solution and other reactants are respectively filled into infusion bottles, and the regulating valve is ensured to be in a closed state to prevent leakage. Open the regulating valve to allow raw materials such as the metal ion solution to enter the first preparation device through the infusion bottle. In the first preparation device, the raw materials are mixed and maintained at an appropriate reaction temperature under the monitoring of the temperature sensor to ensure the smooth progress of the reaction. The raw materials from the first preparation device and the second preparation device enter the continuous reactor through the microfluidic pipeline, where a preliminary reaction takes place. The reaction products are continuously transported to the dynamic reactor through the delivery pipe under the drive of the pump body for further reaction or treatment. In the dynamic reactor, the products undergo further chemical reactions or physical changes to improve their purity or change their properties. The gases generated during the reaction process are discharged through the exhaust pipe, and the possible liquid products are collected through the liquid collection bottle. The refrigeration component in the liquid collection bottle helps prevent the volatilization or degradation of the products. The products pass through the filter, and the filter screen removes impurities and unreacted raw materials to ensure the purity of the final product. Finally, the products enter the distiller and are distilled under the action of the heating component to separate the target product and other by-products, realizing the purification of the products. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] Figure 1 It is a schematic structural diagram of the whole of the present utility model.

[0018] Figure 2 It is a schematic structural diagram of the preparation device of the whole of the present utility model.

[0019] Figure 3 It is a schematic internal structural diagram of the dynamic reactor of the whole of the present utility model.

[0020] Figure 4 It is the whole of the present utility model Figure 1 The enlarged structural diagram at A in the figure.

[0021] The reference numerals are: 1. The whole device; 2. Auxiliary production mechanism; 3. First preparation device; 4. Infusion bottle; 5. Regulating valve; 6. Temperature sensor; 7. Second preparation device; 8. Microfluidic pipeline; 9. Continuous flow reactor; 10. Delivery pipe; 11. Pump body; 12. Dynamic reactor; 13. Third preparation device; 14. Exhaust pipe; 15. Liquid collection bottle; 16. Refrigeration component; 17. Filter; 18. Filter screen; 19. Distiller; 20. Heating component; 21. Drive motor; 22. Stirrer. DETAILED DESCRIPTION OF THE EMBODIMENTS

[0022] Next, the technical solutions in the embodiments of the present invention will be clearly and completely described in conjunction with the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments. All other embodiments obtained by those of ordinary skill in the art based on the embodiments of the present invention without creative efforts shall fall within the protection scope of the present invention.

[0023] Embodiment 1

[0024] As shown in the attached Figures 1-4 A continuous production device suitable for metal amine complexes, including the overall device 1, with an auxiliary production mechanism 2 installed inside the overall device 1; a first dispenser 3 is installed inside the overall device 1, and a liquid infusion bottle 4 is nested on the outer side of the first dispenser 3. A regulating valve 5 is nested at the bottom of the liquid infusion bottle 4. A temperature sensor 6 is installed inside the first dispenser 3. A microfluidic pipeline 8 is nested at the bottom of the first dispenser 3. A second dispenser 7 is nested on one side of the microfluidic pipeline 8. A continuous flow reactor 9 is nested at the bottom of the microfluidic pipeline 8. A delivery pipe 10 is nested on one side of the continuous flow reactor 9. A pump body 11 is nested on the outer side of the delivery pipe 10. A dynamic reactor 12 is nested on the other side of the delivery pipe 10. A third dispenser 13 is nested on the top side of the dynamic reactor 12. An exhaust pipe 14 is nested on the top side of the third dispenser 13. A liquid collection bottle 15 is nested on the other side of the exhaust pipe 14. A refrigeration component 16 is embedded inside the liquid collection bottle 15. A filter 17 is nested on one side of the dynamic reactor 12. A filter screen 18 is embedded inside the filter 17. A distiller 19 is nested on one side of the filter 17. A heating component 20 is nested at the bottom of the distiller 19.

[0025] Among them: The required metal ion solution and other reactants are respectively filled into the infusion bottle 4, and it is ensured that the regulating valve 5 is in the closed state to prevent leakage. Open the regulating valve 5 to allow raw materials such as the metal ion solution to enter the first mixer 3 through the infusion bottle 4. In the first mixer 3, the raw materials are mixed and maintained at an appropriate reaction temperature under the monitoring of the temperature sensor 6 to ensure the smooth progress of the reaction. The raw materials from the first mixer 3 and the second mixer 7 enter the continuous reactor 9 through the microfluidic pipeline 8, where a preliminary reaction takes place. The reaction product is continuously transported to the dynamic reactor 12 through the delivery pipe 10 under the drive of the pump body 11 for further reaction or treatment. In the dynamic reactor 12, the product undergoes further chemical reactions or physical changes to improve its purity or change its properties. The gas generated during the reaction process is discharged through the exhaust pipe 14, and the liquid product that may accompany it is collected through the liquid collection bottle 15. The refrigeration component 16 in the liquid collection bottle 15 helps prevent the product from volatilizing or degrading. The product passes through the filter 17, and the filter screen 18 removes impurities and unreacted raw materials to ensure the purity of the final product. Finally, the product enters the distiller 19 and is distilled under the action of the heating component 20 to separate the target product and other by-products, realizing the purification of the product.

[0026] Embodiment 2

[0027] Based on Embodiment 1, the solution in Embodiment 1 is further refined and introduced in combination with the following specific working methods. See the following description for details:

[0028] As Figure 3 shown, as a preferred implementation; a drive machine 21 is nested and installed at the bottom of the dynamic reactor 12, and a stirrer 22 is nested and installed at the top of the drive machine 21. Further, the stirrer 22 is driven by the drive machine 21 and can generate a strong stirring effect inside the dynamic reactor 12, enabling the reactants to be fully mixed, thereby accelerating the reaction rate and improving the reaction efficiency.

[0029] The working process of the present utility model is as follows:

[0030] When the continuous production device applicable to metal amino complexes is in use, the required metal ion solution and other reactants are respectively filled into the infusion bottle 4, and it is ensured that the regulating valve 5 is in the closed state to prevent leakage. Open the regulating valve 5 to allow raw materials such as the metal ion solution to enter the first mixer 3 through the infusion bottle 4. In the first mixer 3, the raw materials are mixed and maintained at an appropriate reaction temperature under the monitoring of the temperature sensor 6 to ensure the smooth progress of the reaction. The raw materials from the first mixer 3 and the second mixer 7 enter the continuous reactor 9 through the microfluidic pipeline 8, where a preliminary reaction takes place. The reaction products are continuously transported to the dynamic reactor 12 through the delivery pipe 10 under the drive of the pump body 11 for further reaction or treatment. In the dynamic reactor 12, the stirrer 22 is driven by the drive machine 21 and can generate a strong stirring effect inside the dynamic reactor 12, enabling the reactants to be fully mixed, and the products to undergo further chemical reactions or physical changes to improve their purity or change their properties. The gas generated during the reaction process is discharged through the exhaust pipe 14, and the liquid products that may accompany are collected through the liquid collection bottle 15. The refrigeration component 16 in the liquid collection bottle 15 helps prevent the volatilization or degradation of the products. The products pass through the filter 17, and the filter screen 18 removes impurities and unreacted raw materials to ensure the purity of the final product. Finally, the products enter the distiller 19 and are distilled under the action of the heating component 20 to separate the target product and other by-products, realizing the purification of the products. This is the working process and principle of the device.

[0031] Finally, several points should be noted: First, in the description of this application, it should be noted that unless otherwise specified and limited, the terms "installation", "connection", and "coupling" should be understood in a broad sense. It can be a mechanical connection or an electrical connection, or it can be the communication inside two components. It can be directly connected. "Upper", "lower", "left", "right", etc. are only used to represent the relative position relationship. When the absolute position of the object being described changes, the relative position relationship may change;

[0032] Second: In the attached drawings of the disclosed embodiments of the present utility model, only the structures related to the disclosed embodiments are involved. Other structures can refer to the general design. Without conflict, the same embodiment and different embodiments of the present utility model can be combined with each other;

[0033] Finally: The above are only the preferred embodiments of the present utility model and are not used to limit the present utility model. Any modifications, equivalent replacements, improvements, etc. made within the spirit and principle of the present utility model shall be included within the protection scope of the present utility model.

Claims

1. A continuous production device for metal amine complexes, comprising a device as a whole (1), characterized in that: An auxiliary production mechanism (2) is installed inside the overall device (1); The device as a whole (1) is internally installed with a first dispenser (3), an external side of the first dispenser (3) is nested and installed in an infusion bottle (4), a regulating valve (5) is nested and installed at the bottom of the infusion bottle (4), a temperature sensor (6) is installed inside the first dispenser (3), a microfluidic pipeline (8) is nested and installed at the bottom of the first dispenser (3), a second dispenser (7) is nested and installed at one side of the microfluidic pipeline (8), a continuous flow reactor (9) is nested and installed at the bottom of the microfluidic pipeline (8), a delivery tube (10) is nested and installed at one side of the continuous flow reactor (9), a pump body (11) is nested and installed outside the delivery tube (10), and the delivery tube (10) is nested and installed. 0), a dynamic reactor (12) is nested on the other side of the dynamic reactor (12), a third dispenser (13) is nested on the top side of the dynamic reactor (12), an exhaust pipe (14) is nested on the top side of the third dispenser (13), a liquid collecting bottle (15) is nested on the other side of the exhaust pipe (14), a refrigeration component (16) is embedded in the interior of the liquid collecting bottle (15), a filter (17) is nested on one side of the dynamic reactor (12), a filter net (18) is embedded in the interior of the filter (17), a distiller (19) is nested on one side of the filter (17), and a heating component (20) is nested at the bottom of the distiller (19).

2. A continuous production device for metal amine complexes according to claim 1, characterized in that: A driving machine (21) is nested and installed at the bottom of the dynamic reactor (12), and an agitator (22) is nested and installed at the top of the driving machine (21).

3. The continuous production device for metal amine complexes according to claim 1, characterized in that: The infusion bottle (4), regulating valve (5) and temperature sensor (6) are each provided in three numbers and are evenly distributed inside the first dispenser (3), the second dispenser (7) and the third dispenser (13).

4. The continuous production device for metal amine complexes according to claim 1, characterized in that: The pump body (11) is installed between the continuous flow reactor (9) and the dynamic reactor (12).

5. The continuous production device for metal amine complexes according to claim 1, characterized in that: The exhaust pipe (14) is installed between the dynamic reactor (12) and the liquid collecting bottle (15).

6. A continuous production device for metal amine complexes according to claim 1, characterized in that: The refrigeration component (16) is used in conjunction with the liquid collecting bottle (15).

7. A continuous production device for metal amine complexes according to claim 2, characterized in that: The stirrer (22) is installed inside the dynamic reactor (12).

8. The continuous production device for metal amine complexes according to claim 2, characterized in that: The driving machine (21) and the stirrer (22) are used together.