Detachable chromatographic separation reactor

Abstract

The utility model discloses a detachable chromatographic separation reactor which comprises a tank body and a chromatographic separation column, the tank body is of a split structure, and an upper mounting plate and a lower mounting plate for mounting the chromatographic separation column are arranged in the tank body; the lower end of the chromatographic separation column is in a big-end-up cone shape or frustum shape; and the shape of the mounting hole of the lower mounting plate is matched with that of the lower end of the chromatographic separation column. According to the utility model, the tank body is arranged into a split structure, so that the tank body is easy to detach and clean; the lower end of the chromatographic separation column is in a big-end-up cone shape or frustum shape and is matched with the shape of the mounting hole of the lower mounting plate, so that automatic clamping mounting is facilitated.

Description

Technical Field

[0001] The utility model belongs to the technical field of xylose chromatography deacidification, and particularly relates to a detachable chromatographic separation reactor. Background Art

[0002] In the production process of xylose, multiple steps are usually involved. For example, hemicellulose is first hydrolyzed to obtain a hydrolysis solution containing xylose, and then a series of treatments are carried out to improve the purity of xylose. Chromatography deacidification is an important process among them. Currently, the reactor used for chromatography deacidification is based on a single column. The structural configuration of the reactor feed inlet and the single column easily leads to uneven liquid flow. The uneven liquid flow will affect the contact time and exchange effect between the resin and the xylose solution. To address the problem of uneven flow, changing the single tube to a multi-tube structure can solve the problem of uneven flow. However, both single tubes and multi-tubes have problems such as inconvenient installation and difficult cleaning. Summary of the Utility Model

[0003] The utility model aims to provide a detachable chromatographic separation reactor for the problems that the reactor is not easy to install and replace and the equipment is difficult to clean.

[0004] A detachable chromatographic separation reactor includes a tank body and a chromatographic separation column. The tank body is of a split structure, and an upper mounting plate and a lower mounting plate for installing the chromatographic separation column are arranged inside the tank body; the lower end of the chromatographic separation column is in a conical or frustum shape with a larger upper part and a smaller lower part, and the shape of the mounting hole on the lower mounting plate is adapted to the shape of the lower end of the chromatographic separation column.

[0005] Preferably, the tank body includes an upper cylinder, a middle cylinder and a lower cylinder; the upper mounting plate is arranged between the upper cylinder and the middle cylinder, and the lower mounting plate is arranged between the middle cylinder and the lower cylinder.

[0006] Preferably, the chromatographic separation column is a single column.

[0007] Preferably, the chromatographic separation column is a plurality of chromatographic separation columns arranged side by side, and a spraying device is arranged between the feed inlet of the tank body and the chromatographic separation column.

[0008] Preferably, the spraying device includes an annular distribution pipe, the annular distribution pipe is connected to the feed inlet, several transverse distribution pipes communicated with the annular distribution pipe are connected to the inner side of the annular distribution pipe, and through holes for liquid to flow into the chromatographic separation column are arranged below the transverse distribution pipes.

[0009] Preferably, the upper cylinder and the middle cylinder, and the middle cylinder and the lower cylinder are connected by flanges.

[0010] Preferably, two lifting lugs are arranged on the upper mounting plate.

[0011] Preferably, a maintenance observation port is arranged on the tank body.

[0012] Preferably, the lower cylinder is conical and provided with a discharge port at the lower part.

[0013] Preferably, the lower cylinder is provided with two support frames.

[0014] In summary, due to the adoption of the above technical solutions, the beneficial effects of the present utility model are as follows:

[0015] First, the present utility model sets the tank body as an upper cylinder, a middle cylinder and a lower cylinder connected in sequence. The upper tube distribution plate is installed between the upper cylinder and the middle cylinder, and the lower mounting plate is installed between the middle cylinder and the lower cylinder. The tank body is divided into three sections for easy disassembly and cleaning, which is beneficial for maintenance and reduces the time occupied by on-line maintenance in process production.

[0016] Second, the lower end of the chromatographic separation column of the present utility model is in a conical or frustum shape with a larger upper part and a smaller lower part, which is adapted to the shape of the mounting hole of the lower mounting plate. The purpose of the lower end of the chromatographic separation column being in a conical or frustum shape with a larger upper part and a smaller lower part is beneficial for automatic clamping installation.

[0017] Third, the present utility model sets a spraying device composed of an annular distribution pipe and a transverse distribution pipe. On the one hand, the annular distribution pipe is connected to a plurality of transverse distribution pipes. When the liquid material flows into the annular distribution pipe and then into a plurality of transverse distribution pipes, the liquid material finally flows into a plurality of chromatographic separation columns through the through holes of the transverse distribution pipes, ensuring that the flow of the liquid material has only two components parallel to the tube bundle and perpendicular to the tube bundle, ensuring the uniformity of the liquid flow, and thus ensuring the contact time and exchange effect between the resin and the xylose solution. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] In order to more clearly illustrate the technical solutions of the embodiments of the present utility model, the following will briefly introduce the drawings required for the embodiments. It should be understood that the following drawings only show some embodiments of the present utility model, and therefore should not be regarded as limiting the scope. For those of ordinary skill in the art, other related drawings can also be obtained based on these drawings without creative efforts.

[0019] Figure 1 It is a schematic structural diagram of the present utility model;

[0020] Figure 2 It is a schematic structural diagram of the upper mounting plate of the present utility model;

[0021] Figure 3 It is a schematic structural diagram of the annular distribution pipe and the transverse distribution pipe of the present utility model;

[0022] Figure 4 It is a schematic structural diagram of the chromatographic separation column of the present utility model;

[0023] Figure 5 It is a schematic structural diagram of the bottom hole of the chromatographic separation column of the present utility model;

[0024] Figure 6 This is a schematic diagram of the horizontal distribution pipe structure of the present utility model. Description of the drawings:

[0026] 1 - upper cylinder body, 11 - first observation port, 12 - first feed port, 13 - second feed port, 14 - annular distribution pipe, 15 - horizontal distribution pipe, 16 - upper mounting plate, 2 - middle cylinder body, 21 - chromatography separation column, 211 - bottom hole, 22 - second observation port, 3 - lower cylinder body, 31 - support frame, 32 - discharge port, 33 - lower mounting plate, 4 - lifting lug Specific embodiments

[0027] To make the objectives, technical solutions and advantages of the embodiments of the present utility model clearer, the technical solutions in the embodiments of the present utility model will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present utility model. Apparently, the described embodiments are some but not all of the embodiments of the present utility model. Usually, the components of the embodiments of the present utility model described and shown in the drawings here can be arranged and designed in various different configurations.

[0028] Therefore, the following detailed description of the embodiments of the present utility model provided in the drawings is not intended to limit the scope of the claimed present utility model, but merely represents the selected embodiments of the present utility model. All other embodiments obtained by those of ordinary skill in the art based on the embodiments of the present utility model without creative efforts fall within the protection scope of the present utility model.

[0029] Such as Figure 1-6 , a detachable chromatography separation reactor, including a tank body and a chromatography separation column 21. The tank body is a split structure. For the split structure of the tank body of the present utility model, except for the upper cylinder body, middle cylinder body, and lower cylinder body structures in the drawings, other splitting methods are within the protection scope of the present utility model. An upper mounting plate 16 and a lower mounting plate 33 for installing the chromatography separation column 21 are provided in the tank body; the lower end of the chromatography separation column 21 is in a conical or frustum shape with a larger upper part and a smaller lower part. Specifically, the conical shape can be a circular cone or a square cone, and a downward step can be provided below the conical shape. The shape of the mounting hole of the lower mounting plate 33 is adapted to the shape of the lower end of the chromatography separation column 21.

[0030] Specifically, the tank body includes an upper cylinder body 1, a middle cylinder body 2, and a lower cylinder body 3; the upper mounting plate 16 is arranged between the upper cylinder body 1 and the middle cylinder body 2, and the lower mounting plate 33 is arranged between the middle cylinder body 2 and the lower cylinder body 3.

[0031] Specifically, the chromatography separation column 21 can be a single column or multiple chromatography separation columns arranged side by side. Specifically, a plurality of bottom holes are provided below the chromatography separation column, such as Figure 5As shown, the aperture of the bottom hole is smaller than the average particle size of the ion exchange particles selected; preferably, a spraying device is arranged between the feed inlet of the tank body and a plurality of chromatographic separation columns 21; specifically, the spraying device includes an annular distribution pipe 14, the annular distribution pipe 14 is connected to the feed inlet, and a plurality of transverse distribution pipes 15 communicated with the annular distribution pipe 14 are connected to the inner side of the annular distribution pipe 14. Through holes for liquid to flow into the chromatographic separation columns are arranged below the transverse distribution pipes 15. When the feed liquid enters the annular distribution pipe from the feed inlet, the feed liquid in the annular distribution pipe enters the plurality of transverse distribution pipes, so that the feed liquid enters the chromatographic separation columns in the middle cylinder through the through holes of the transverse distribution pipes.

[0032] Specifically, the upper cylinder body 1, the middle cylinder body 2 and the middle cylinder body 2 and the lower cylinder body 3 are connected by flanges.

[0033] Specifically, two lifting lugs 4 are arranged on the upper mounting plate 16, so as to easily take out the upper mounting plate 16 from the reactor.

[0034] Specifically, a maintenance observation port is arranged on the tank body. Preferably, a first observation port 11 is arranged on the upper cylinder body 1 and / or a second observation port 22 is arranged on the lower cylinder body.

[0035] Specifically, the lower cylinder body 3 is in a conical shape, and a discharge port 32 is arranged at the lower part.

[0036] Specifically, two support frames 31 are arranged on the lower cylinder body 3 for support and fixation.

[0037] Embodiment

[0038] A detachable chromatographic separation reactor includes a tank body and chromatographic separation columns 21. The tank body is of a split structure, and an upper mounting plate 16 and a lower mounting plate 33 for mounting the chromatographic separation columns 21 are arranged in the tank body; the lower end of the chromatographic separation column 21 is in a conical shape with a larger upper part and a smaller lower part. Specifically, the conical shape is a square cone, and a downward step can also be arranged below the conical shape. The shape of the mounting hole of the lower mounting plate 33 is adapted to the shape of the lower end of the chromatographic separation column 21.

[0039] Specifically, the tank body includes an upper cylinder body 1, a middle cylinder body 2 and a lower cylinder body 3; the upper mounting plate 16 is arranged between the upper cylinder body 1 and the middle cylinder body 2, and the lower mounting plate 33 is arranged between the middle cylinder body 2 and the lower cylinder body 3.

[0040] Specifically, the chromatographic separation columns 21 are a plurality of chromatographic separation columns arranged side by side. Specifically, a plurality of bottom holes are arranged below the chromatographic separation columns, such as Figure 5As shown, the aperture of the bottom hole is smaller than the average particle size of the ion exchange particles selected; preferably, a spraying device is provided between the feed inlet of the tank body and the plurality of chromatographic separation columns 21; specifically, the spraying device includes an annular distribution pipe 14, the annular distribution pipe 14 is connected to the feed inlet, and several transverse distribution pipes 15 communicating with the annular distribution pipe 14 are connected to the inner side of the annular distribution pipe 14. Through holes for liquid to flow into the chromatographic separation columns are provided below the transverse distribution pipes 15. When the feed liquid enters the annular distribution pipe from the feed inlet, the feed liquid in the annular distribution pipe enters the plurality of transverse distribution pipes, so that the feed liquid enters the chromatographic separation columns in the middle cylinder through the through holes of the transverse distribution pipes.

[0041] Specifically, the upper cylinder 1, the middle cylinder 2, and the middle cylinder 2 and the lower cylinder 3 are connected by flanges.

[0042] Specifically, two lifting lugs 4 are provided on the upper mounting plate 16 for the purpose of easily taking out the upper mounting plate 16 from the reactor.

[0043] Specifically, a maintenance observation port is provided on the tank body; preferably, a first observation port 11 is provided on the upper cylinder 1 and a second observation port 22 is provided on the lower cylinder.

[0044] Specifically, the lower cylinder 3 is conical and a discharge port 32 is provided at the lower part.

[0045] Specifically, two support frames 31 are provided on the lower cylinder 3 for support and fixation.

[0046] The above are only the preferred embodiments of the present invention and are not used to limit the present invention. For those skilled in the art, the present invention can have various changes and modifications. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present invention shall be included in the protection scope of the present invention.

Claims

1. A detachable chromatography separation reactor, comprising a tank body and a chromatography separation column, characterized in that, The tank body has a split structure, and an upper mounting plate and a lower mounting plate for installing a chromatography separation column are arranged inside the tank body; the lower end of the chromatography separation column is in a conical or frustum shape with a larger upper part and a smaller lower part, and the shape of the mounting hole of the lower mounting plate is adapted to the shape of the lower end of the chromatography separation column.

2. The disassembled chromatographic separation reactor according to claim 1, characterized in that, The tank body includes an upper cylinder body, a middle cylinder body and a lower cylinder body; the upper mounting plate is arranged between the upper cylinder body and the middle cylinder body, and the lower mounting plate is arranged between the middle cylinder body and the lower cylinder body.

3. The disassembled chromatography separation reactor according to claim 1 or 2, characterized in that, The chromatography separation column is a single column.

4. The detachable chromatography separation reactor according to claim 1 or 2, wherein, The chromatography separation column is a plurality of chromatography separation columns arranged side by side, and a spraying device is arranged between the feed inlet of the tank body and the chromatography separation column.

5. The disassembled chromatography separation reactor according to claim 4, characterized in that, The spraying device includes an annular distribution pipe, the annular distribution pipe is connected to the feed inlet, several transverse distribution pipes communicated with the annular distribution pipe are connected to the inner side of the annular distribution pipe, and through holes for liquid to flow into the chromatography separation column are arranged below the transverse distribution pipes.

6. The disassembled chromatography separation reactor according to claim 2, wherein, The upper cylinder body and the middle cylinder body, and the middle cylinder body and the lower cylinder body are connected by flanges.

7. The disassembled chromatographic separation reactor according to claim 1 or 2, characterized in that, Two lifting lugs are arranged on the upper mounting plate.

8. The disassembled chromatographic separation reactor according to claim 1 or 2, characterized in that, An inspection and observation port is arranged on the tank body.

9. The disassembled chromatographic separation reactor according to claim 2, characterized in that, The lower cylinder body is conical, and a discharge port is arranged at the lower part.

10. The disassembled chromatographic separation reactor according to claim 2, characterized in that, Two support frames are arranged on the lower cylinder body.

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