Kit capable of rapidly preparing gel

By designing a kit that quickly configures the gel, using docking holes and drainage pipes to connect, the existing kits are solved for cumbersome sampling and contamination, and a fast and safe sampling process is achieved, improving experimental efficiency and safety.

CN223077972UActive Publication Date: 2025-07-08TONGLING EPIZYME BIOMEDICAL TECHNOLOGY CO LTD
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Patent Information

Application Number
CN202422137235.7
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-09-02
Publication Date
2025-07-08
Estimated Expiration
2034-09-02

AI Technical Summary

Technical Problem

The sampling process of existing kits is cumbersome and prone to contamination of reagents, increasing the risk of experimenters being exposed to toxic substances.

Method used

A reagent kit that can quickly configure the gel is designed, including a box, a reagent bottle and a sampling mechanism. It is connected to the drain pipe through a docking hole to achieve sampling without opening the reagent bottle cap, and the opening and closing is controlled through a sealing ring to avoid contamination and contact with toxic substances.

Benefits of technology

A fast and safe sampling process is achieved, avoiding the risk of reagent contamination and personnel exposure to toxic substances, and improving experimental efficiency and safety.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model relates to the technical field of kits, in particular to a kit capable of quickly preparing gel, which comprises a kit body and a reagent bottle placed in the kit body, a sampling mechanism is arranged in the reagent bottle, a placing cavity is arranged on the kit body, and a liquid discharge pipe is placed in the placing cavity; a butt joint hole is formed in the peripheral wall of the reagent bottle and is used for connecting the liquid discharge pipe. According to the kit capable of rapidly preparing the gel, through cooperation of the sampling mechanism and the liquid discharging pipe, rapid sampling can be achieved, in the sampling process, the top of a reagent bottle does not need to be opened, an external sampling pipe does not need to be inserted into a reagent, pollution to the reagent in the bottle is avoided, meanwhile, an experimenter can be prevented from making contact with toxic substances, and the operation is convenient. And the safety of the experiment is improved.
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Description

Technical Field

[0001] The utility model relates to the technical field of reagent kits, in particular to a reagent kit capable of quickly preparing gel. Background Art

[0002] Gel electrophoresis is a widely used technique in life science laboratories for separating macromolecules such as DNA, RNA, and proteins. When conducting a gel electrophoresis experiment, it is necessary to select an appropriate reagent ratio according to the molecular weight of the target protein and prepare a certain amount of gel on site. Currently, it is prepared using the reagents and tools provided by a gel preparation reagent kit.

[0003] However, currently, it is not convenient to extract the reagent solution from the reagent kit. When extracting, it is necessary to open the bottle cap of the reagent bottle and then insert the sampling tube into the reagent for sampling. On the one hand, the steps are cumbersome, reducing the operation efficiency; on the other hand, it is easy to contaminate the reagent in the bottle, affecting the subsequent use effect. In addition, sampling in this way will increase the probability of contact between laboratory personnel and toxic substances such as Acr-Bis, affecting the life and health of laboratory personnel. Content of the Utility Model

[0004] The purpose of the embodiment of the utility model is to provide a reagent kit capable of quickly preparing gel, which solves the problem of inconvenient sampling when the current reagent kit is in use.

[0005] To achieve the above purpose, the utility model provides the following technical solutions:

[0006] A reagent kit capable of quickly preparing gel, including a box body and reagent bottles placed in the box body. A sampling mechanism is arranged in the reagent bottles, and a placement cavity is arranged on the box body, and a drainage tube is placed in the placement cavity;

[0007] A docking hole is opened on the outer peripheral wall of the reagent bottle for connecting the drainage tube.

[0008] Preferably, the sampling mechanism includes a liquid extraction tube fixedly connected to the inner wall of the reagent bottle. The top end of the liquid extraction tube penetrates through the reagent bottle and is fixedly connected with a rubber cap. The bottom end of the liquid extraction tube is connected with a liquid extraction pipe and a liquid outlet pipe through a diversion device. The end of the liquid outlet pipe far from the diversion device is fixedly connected to the inner wall of the docking hole and can be threadedly connected to one end of the drainage tube.

[0009] Preferably, the diversion device includes a housing fixedly connected to the inner wall of the reagent bottle. The liquid extraction tube, the liquid extraction pipe, and the liquid outlet pipe are all fixedly inserted into the inner wall of the housing;

[0010] A cavity is formed inside the housing. A piston in the cavity is connected to a sealing block. The sealing block can seal one end of the liquid outlet pipe, and the bottom end of the sealing block is connected to the inner wall of the housing through a spring. A concave-shaped diversion channel is formed inside the housing, and both ends of the diversion channel communicate with the inside of the cavity.

[0011] Preferably, a first stop portion is provided on the inner top wall of the cavity, and a second stop portion is provided on the inner bottom wall of the cavity. The first stop portion and the second stop portion are respectively used to contact both ends of the sealing block.

[0012] Preferably, the inner bottom wall of the reagent bottle is a conical surface, and a groove is formed downward at the center position of the conical surface. The bottom end of the liquid extraction pipe is located in the groove.

[0013] Preferably, a sealing ring is threadedly connected to the outer peripheral wall of the reagent bottle to control the opening and closing of the docking hole. A plurality of convex blocks are fixedly connected to the outer peripheral wall of the sealing ring.

[0014] Preferably, a placement platform is fixedly connected inside the box body, and the bottom end of the reagent bottle is movably inserted into the placement platform.

[0015] By means of the above technical solution, the present utility model provides a reagent kit for quickly preparing gel, which has at least the following beneficial effects:

[0016] (1) For the reagent kit for quickly preparing gel, through the cooperation of the sampling mechanism and the liquid discharge pipe, rapid sampling can be achieved. During the sampling process, it is not necessary to open the top of the reagent bottle, nor to insert an external sampling pipe into the reagent, which avoids contamination of the reagent in the bottle and also prevents experimental personnel from contacting toxic substances, improving the safety of the experiment.

[0017] (2) For the reagent kit for quickly preparing gel, by setting the sealing ring, the opening and closing of the docking hole can be controlled, so that after sampling, the reagent bottle can be quickly sealed to avoid contamination inside the reagent bottle. By arranging a conical surface and a groove inside the reagent bottle, the reagent in the bottle can be collected to avoid waste of residual liquid. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] The drawings described herein are used to provide a further understanding of the present utility model and form a part of this application:

[0019] Figure 1 It is a schematic diagram of the overall structure of an embodiment of the present utility model;

[0020] Figure 2 It is a schematic diagram of the structure of the docking hole and the liquid discharge pipe in an embodiment of the present utility model;

[0021] Figure 3It is a cross-sectional view of the reagent bottle in the embodiment of the present utility model;

[0022] Figure 4 It is a cross-sectional view of the sampling mechanism in the embodiment of the present utility model;

[0023] Figure 5 It is Figure 4 the enlarged structural schematic diagram at position A in

[0024] Figure 6 It is Figure 4 the enlarged structural schematic diagram at position B in

[0025] Figure 7 It is a cross-sectional view of the housing in the embodiment of the present utility model;

[0026] Figure 8 It is Figure 3 the enlarged structural schematic diagram at position C in

[0027] In the figure: 1, box body; 2, reagent bottle; 201, docking hole; 202, conical surface; 203, groove; 3, sampling mechanism; 301, liquid suction pipe; 302, rubber cap; 303, housing; 3031, diversion channel; 3032, first stop portion; 3033, second stop portion; 304, liquid extraction pipe; 305, liquid outlet pipe; 306, sealing block; 307, spring; 4, drain pipe; 5, placement table; 6, sealing ring; 7, convex block. Specific embodiments

[0028] Next, the technical solutions in the embodiments of the present utility model will be clearly and completely described in conjunction with the accompanying drawings in the embodiments of the present utility model. Obviously, the described embodiments are only a part of the embodiments of the present utility model, rather than all of the embodiments. All other embodiments obtained by those of ordinary skill in the art based on the embodiments of the present utility model without creative efforts shall fall within the protection scope of the present utility model.

[0029] Please refer to Figures 1-8 , a technical solution provided by the present utility model:

[0030] A reagent kit capable of quickly preparing gel includes a box body 1. A placement table 5 is fixedly connected inside the box body 1. A plurality of slots (not shown in the figure) are opened at the top of the placement table 5. A plurality of reagent bottles 2 are movably inserted into the slots. The placement table 5 is in a stepped shape to adapt to reagent bottles 2 of different heights. A sampling mechanism 3 is arranged inside the reagent bottle 2 for extracting the reagent inside the reagent bottle 2. A placement cavity is arranged on the box body 1, and a drain pipe 4 is placed in the placement cavity. The drain pipe 4 is used to cooperate with the sampling mechanism 3 to export the reagent inside the reagent bottle 2 out of the bottle body.

[0031] Please refer to Figure 2, a docking hole 201 is provided on the peripheral wall of the reagent bottle 2 for connecting the drain pipe 4, so that the purpose of sampling can be achieved without taking the sampling mechanism 3 out of the reagent bottle 2. A sealing ring 6 is threadedly connected to the peripheral wall of the reagent bottle 2 for controlling the opening and closing of the docking hole 201. When sampling is required, the sealing ring 6 can be rotated downward to open the docking hole 201. After sampling is completed, the sealing ring 6 can be rotated upward to close the docking hole 201 by the sealing ring 6 to prevent the inside of the reagent bottle 2 from being contaminated. A plurality of protrusions 7 are fixedly connected to the peripheral wall of the sealing ring 6 to facilitate the rotation of the sealing ring 6.

[0032] Specifically, the sampling mechanism 3 in the present embodiment includes a liquid extraction tube 301 fixedly connected to the inner wall of the reagent bottle 2, the top of the liquid extraction tube 301 penetrates the reagent bottle 2 and is fixedly connected with a rubber cap 302, and by controlling the deformation degree of the rubber cap 302, the air pressure in the liquid extraction tube 301 can be controlled, thereby controlling the extraction and discharge of liquid. The liquid extraction tube 301 is a glass tube, and a scale line (not shown in the figure) is provided on its surface to facilitate the control of the amount of liquid extraction. The bottom end of the liquid extraction tube 301 is connected with a liquid extraction tube 304 and a liquid outlet tube 305 through a flow guide device, and one end of the liquid outlet tube 305 away from the flow guide device is fixedly connected to the inner wall of the docking hole 201, and can be threadedly connected with one end of the liquid discharge tube 4, thereby facilitating the connection and disassembly of the liquid discharge tube 4 and the liquid outlet tube 305.

[0033] See also Figure 5 The flow guiding device includes a shell 303 fixedly connected to the inner wall of the reagent bottle 2, and the liquid extraction tube 301, the liquid collection tube 304, and the liquid outlet tube 305 are all fixedly plugged into the inner wall of the shell 303, wherein the liquid extraction tube 301 and the liquid collection tube 304 are respectively plugged into the inner walls of the two opposite ends of the shell 303, and the liquid outlet tube 305 is plugged into the inner wall of the shell 303 along the radial direction. A cavity is opened inside the shell 303, and the liquid extraction tube 301, the liquid collection tube 304, and the liquid outlet tube 305 are all connected to the inside of the cavity. The piston in the cavity is connected to a sealing block 306, which can seal one end of the liquid outlet pipe 305, and the bottom end of the sealing block 306 is connected to the inner wall of the shell 303 through a spring 307. When the air pressure above the sealing block 306 increases to a certain value, the sealing block 306 can be pushed to move downward to release its sealing effect on one end of the liquid outlet pipe 305, so that the fluid in the liquid extraction tube 301 can be discharged through the liquid outlet pipe 305.

[0034] Combination Figure 5 and Figure 7As shown, a first stop portion 3032 is provided on the inner top wall of the cavity, and a second stop portion 3033 is provided on the inner bottom wall of the cavity. The first stop portion 3032 and the second stop portion 3033 are respectively used to contact the two ends of the sealing block 306 to limit the upward and downward movement strokes of the sealing block 306 and ensure the sealing and unsealing effects. A concave-shaped diversion channel 3031 is formed inside the housing 303. Both ends of the diversion channel 3031 communicate with the inside of the cavity, and the top end of the diversion channel 3031 is located above the first stop portion 3032. When the top end of the sealing block 306 contacts the first stop portion 3032, the bottom end of the diversion channel 3031 is in communication with the inner cavity of the reagent bottle 2, so that the liquid in the liquid extraction tube 304 can be drawn into the liquid suction tube 301.

[0035] Please refer to Figure 8 , the inner bottom wall of the reagent bottle 2 is a conical surface 202. A groove 203 is formed downward at the center position of the conical surface 202. The bottom end of the liquid extraction tube 304 is located in the groove 203. Through the conical surface 202, the reagent in the reagent bottle 2 can be introduced into the groove 203, which is convenient for the liquid extraction tube 304 to extract, thus avoiding the waste of remaining liquid.

[0036] When the gel-rapidly configurable kit of the present invention is in use, first, the sealing ring 6 is rotated by the convex block 7. During the rotation of the sealing ring 6, it moves downward, so that the docking hole 201 is exposed. Subsequently, the drain pipe 4 is threadedly connected to the liquid outlet pipe 305 in the docking hole 201, and the bottom end of the drain pipe 4 is extended into the container. Subsequently, the rubber cap 302 is quickly squeezed, so that the gas in the rubber cap 302 quickly enters the housing 303 through the liquid suction tube 301, pushing the sealing block 306 downward, blocking the opening at the bottom end of the diversion channel 3031, and opening one end of the liquid outlet pipe 305. The gas is discharged out of the device through the liquid outlet pipe 305. After the air pressure decreases, the sealing block 306 moves upward under the elastic force of the spring 307 to block one end of the liquid outlet pipe 305 again. Subsequently, the rubber cap 302 is slowly released to make the inside of the liquid suction tube 301 in a negative pressure state. The liquid in the reagent bottle 2 enters the liquid suction tube 301 through the liquid extraction tube 304, the cavity and the diversion channel 3031. After a certain amount of liquid is taken, the rubber cap 302 is quickly squeezed again, so that the reagent enters the container through the liquid outlet pipe 305 and the drain pipe 4.

[0037] After the liquid extraction is completed, the drain pipe 4 is threadedly separated from the liquid outlet pipe 305, and then the sealing ring 6 is rotated in the reverse direction to re-seal the docking hole 201 to prevent the inside of the reagent bottle 2 from being contaminated.

[0038] It should be noted that in this text, relational terms such as first and second are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any actual relationship or order between these entities or operations. Moreover, the terms "comprising", "including" or any other variant thereof are intended to cover non-exclusive inclusion, such that a process, method, article or apparatus comprising a series of elements includes not only those elements but also other elements not expressly listed, or elements inherent to such process, method, article or apparatus.

[0039] Although the embodiments of the present utility model have been shown and described, for those of ordinary skill in the art, it can be understood that various changes, modifications, substitutions and variations can be made to these embodiments without departing from the principles and spirit of the present utility model, and the scope of the present utility model is defined by the appended claims and their equivalents.

Claims

1. A kit for rapidly configuring a gel, comprising a box body (1) and reagent bottles (2) placed inside the box body (1), characterized in that, A sampling mechanism (3) is arranged inside the reagent bottle (2), and a placement cavity is arranged on the box body (1), and a drain pipe (4) is placed in the placement cavity; A docking hole (201) is formed on the outer peripheral wall of the reagent bottle (2) for connecting the drain pipe (4).

2. The kit for rapidly configuring a gel according to claim 1, wherein The sampling mechanism (3) includes a liquid extraction pipe (301) fixedly connected to the inner wall of the reagent bottle (2). The top end of the liquid extraction pipe (301) penetrates through the reagent bottle (2) and is fixedly connected with a rubber cap (302). The bottom end of the liquid extraction pipe (301) is connected with a liquid extraction tube (304) and a liquid outlet pipe (305) through a diversion device. One end of the liquid outlet pipe (305) far away from the diversion device is fixedly connected to the inner wall of the docking hole (201) and can be threadedly connected with one end of the drain pipe (4).

3. The kit for rapidly configuring a gel according to claim 2, wherein The diversion device includes a housing (303) fixedly connected to the inner wall of the reagent bottle (2). The liquid extraction pipe (301), the liquid extraction tube (304), and the liquid outlet pipe (305) are all fixedly inserted into the inner wall of the housing (303); A cavity is formed inside the housing (303), and a sealing block (306) is piston-connected inside the cavity. The sealing block (306) can seal one end of the liquid outlet pipe (305), and the bottom end of the sealing block (306) is connected to the inner wall of the housing (303) through a spring (307). An inverted U-shaped diversion channel (3031) is formed inside the housing (303), and both ends of the diversion channel (3031) communicate with the inside of the cavity.

4. The kit for rapidly configuring a gel according to claim 3, characterized in that, A first stop portion (3032) is arranged on the inner top wall of the cavity, and a second stop portion (3033) is arranged on the inner bottom wall of the cavity. The first stop portion (3032) and the second stop portion (3033) are respectively used for contacting with both ends of the sealing block (306).

5. The kit for rapidly configuring a gel according to claim 2, wherein, The inner bottom wall of the reagent bottle (2) is a conical surface (202), and a groove (203) is formed downward at the central position of the conical surface (202). The bottom end of the liquid extraction tube (304) is located inside the groove (203).

6. The kit for rapidly configuring a gel according to claim 1, characterized in that, A sealing ring (6) is threadedly connected to the outer peripheral wall of the reagent bottle (2) for controlling the opening and closing of the docking hole (201). A plurality of convex blocks (7) are fixedly connected to the outer peripheral wall of the sealing ring (6).

7. The kit for rapidly configuring a gel according to claim 1, wherein A placement table (5) is fixedly connected to the inside of the box body (1), and the bottom end of the reagent bottle (2) is movably inserted into the placement table (5).