Pumping catheter assembly and ventricular assist device

Abstract

The embodiment of the utility model provides a blood pumping catheter assembly and a ventricular assist device, the blood pumping catheter assembly comprises a catheter and a smooth layer, a perfusion passage is formed in the catheter, and when the catheter intervenes into the body of a patient, perfusion liquid can be injected into the perfusion passage to prevent blood of the patient from flowing into the catheter. On the path of the perfusion channel, the side wall corresponding to the perfusion channel is a first surface, the smooth layer is arranged on at least part of the first surface, when the perfusion channel is filled with perfusion liquid, the perfusion liquid can make contact with the smooth layer instead of making contact with the first surface of the catheter, and the surface roughness of the smooth layer is smaller than that of the first surface; the smooth layer is arranged on the first surface, so that the surface of the smooth layer is smoother relative to the first surface, bubbles are not easy to adhere to the smooth layer, the bubbles in a perfusion passage can be discharged, on one hand, the risk of aeroembolism caused by the bubbles entering the body of a patient can be reduced, the safety performance is improved, on the other hand, the perfusion effect of the blood pumping catheter can be improved, and the reliability of the catheter is improved.

Description

Technical Field

[0001] This application belongs to the technical field of medical devices, and particularly relates to a blood pumping catheter assembly and a ventricular assist device. Background Art

[0002] A blood pumping catheter can be inserted into a patient's body. For example, it can pump the blood in the patient's left ventricle to the ventricle to assist the ventricle in working. In the prior art, a perfusion passage is provided inside the blood pumping catheter, and a perfusion component is used to deliver perfusion fluid to the perfusion passage to prevent blood from entering the inside of the catheter through the gap.

[0003] Currently, the perfusion passage is usually filled with a large amount of gas (such as air) before injecting the perfusion fluid. Although most of the gas will be discharged from the catheter due to the extrusion of the perfusion fluid, a small part of the gas may still remain in the perfusion passage to form microbubbles. These microbubbles are easily adhered to the corresponding inner wall of the perfusion passage and are not easy to discharge, which affects the safety of the patient and also affects the safety of using the blood pumping catheter. Summary of the Utility Model

[0004] The embodiments of this application provide a blood pumping catheter assembly and a ventricular assist device, which can improve the safety and reliability of the catheter.

[0005] In the first aspect of this application, a blood pumping catheter assembly is provided, which includes a catheter and a smooth layer. A perfusion passage is formed inside the catheter. On the path of the perfusion passage, the side wall corresponding to the perfusion passage is the first surface; the smooth layer is provided on at least part of the first surface, and the surface roughness of the smooth layer is less than the surface roughness of the first surface.

[0006] In some embodiments, the smooth layer is configured as a hydrophilic layer.

[0007] In some embodiments, the surface roughness Ra of the smooth layer satisfies: Ra < 0.5 micrometers.

[0008] In some embodiments, the catheter includes a first sub-tube and a second sub-tube sleeved on the outer periphery of the first sub-tube. A first sub-passage is formed between the first sub-tube and the second sub-tube, and a second sub-passage is formed inside the first sub-tube. The first sub-passage and the second sub-passage are only connected at the distal end. The first sub-passage and the second sub-passage together form the perfusion passage, and the first surface includes at least one of the surface of the first sub-tube facing the first sub-passage, the surface of the first sub-tube facing the second sub-passage, and the surface of the second sub-tube facing the first sub-passage.

[0009] In some embodiments, the blood pumping catheter assembly further includes an impeller rotating shaft, which is arranged at the distal end of the second sub-tube and is used to connect with a motor. The first surface further includes at least part of the surface of the impeller rotating shaft in contact with the perfusion fluid.

[0010] In some embodiments, the blood pumping catheter assembly further includes a drive shaft and a bearing, at least a portion of the drive shaft is located in the second sub-passageway, the bearing is located in the second sub-passageway and is sleeved on the drive shaft, and the first surface includes at least a portion of the surface on the drive shaft and / or the bearing that contacts the perfusion fluid.

[0011] In some embodiments, the first sub-tube includes a tube body and a bearing stop ring connected to the tube body, the drive shaft protrudes along its own radial direction to form a convex portion, the bearing stop ring is arranged around the circumference of the drive shaft and is spaced apart from the convex portion, the bearing is located between the bearing stop ring and the convex portion, and the first surface also includes at least a portion of the surface of the tube body and / or the bearing stop ring facing the perfusion passage.

[0012] In some embodiments, the tube body includes a sheath tube, a first sealing cover and a first connecting portion which are connected in sequence along the axial direction of the drive shaft toward the distal end, the bearing stop ring is connected to the first connecting portion, the first sealing cover and the bearing stop ring are located on both sides of the bearing along the axial direction of the drive shaft, the first connecting portion is arranged on the side of the bearing away from the drive shaft along the radial direction of the drive shaft, and the first surface also includes at least a portion of the surface of at least one of the sheath tube, the first sealing cover and the first connecting portion facing the perfusion passage.

[0013] In some embodiments, the second sub-tube includes a tube body, a second connecting portion and a second sealing cover connected in sequence, the tube body is arranged around the circumference of the first sub-tube, the second sealing cover is located on one side of the first sub-tube along the axial direction of the first sub-tube, and the first surface also includes at least a portion of the surface of at least one of the tube body, the second connecting portion and the second sealing cover facing the perfusion passage.

[0014] A second aspect of the present application provides a ventricular assist device comprising any of the above blood pumping catheter assemblies.

[0015] As described in the background technology, when the catheter is inserted into the patient's body, the patient's blood can be blocked from flowing into the catheter by injecting perfusion fluid into the perfusion passage. In the blood pumping catheter assembly and ventricular assist device of the embodiment of the present application, on the path of the perfusion passage, the side wall corresponding to the perfusion passage is the first surface, and the smooth layer is arranged on at least part of the first surface. When the perfusion passage is filled with perfusion fluid, the perfusion fluid can contact the smooth layer instead of the first surface of the catheter. Since the surface roughness of the smooth layer is less than the surface roughness of the first surface, the surface of the smooth layer is smoother than the first surface, and it is not easy to adhere to bubbles, so it is conducive to the discharge of bubbles in the perfusion passage during pre-perfusion. On the one hand, it can reduce the risk of bubbles entering the patient's body and causing air embolism, improve safety performance, and on the other hand, it can also improve the perfusion effect of the blood pumping catheter and improve the reliability of the catheter. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] To more clearly illustrate the technical solutions of the embodiments of the present application, the following will briefly introduce the drawings required for use in the embodiments of the present application. For those of ordinary skill in the art, without creative efforts, other drawings can also be obtained based on these drawings.

[0017] Figure 1 is a schematic cross-sectional view of a blood pumping catheter assembly provided by some embodiments of the present application;

[0018] Figure 2 is a partial cross-sectional view of a blood pumping catheter assembly provided by some embodiments of the present application.

[0019] Marking name:

[0020] Catheter 10; first sub-tube 101; second sub-tube 102; tube body 103; bearing stop ring 104; sheath 105; first sealing cover 106; first connecting portion 107; tube body 108; second connecting portion 109; perfusion passage 11; second sealing cover 110; first sub-passage 111; second sub-passage 112; first surface 12; impeller rotating shaft 13; drive shaft 14; first rotating shaft 141; second rotating shaft 142; convex portion 143; bearing 15. Detailed implementation manners

[0021] The following will describe in detail the features and exemplary embodiments of various aspects of the present application. To make the objectives, technical solutions and advantages of the present application clearer and more understandable, the present application will be further described in detail below in conjunction with the drawings and specific embodiments. It should be understood that the specific embodiments described herein are only configured to explain the present application and are not configured to limit the present application. For those skilled in the art, the present application can be implemented without some of these specific details. The following description of the embodiments is only provided to provide a better understanding of the present application by showing examples of the present application.

[0022] It should be noted that in this document, relational terms such as first and second are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any actual relationship or order between these entities or operations. Moreover, the term "comprising", "including" or any other variation thereof is intended to cover non-exclusive inclusion, so that a process, method, article or device including a series of elements not only includes those elements, but also includes other elements not expressly listed, or also includes elements inherent to such process, method, article or device. Without further limitation, the elements defined by the statement "including..." do not exclude the existence of additional identical elements in the process, method, article or device including the said elements.

[0023] To solve the problems of the prior art, an embodiment of the present application provides a blood pumping catheter assembly and a ventricular assist device. First, the blood pumping catheter assembly provided by the embodiment of the present application will be introduced below.

[0024] Figure 1 It is a schematic cross-sectional view of a blood pumping catheter assembly provided by some embodiments of the present application, Figure 2 It is a partial cross-sectional view of a blood pumping catheter assembly provided by some embodiments of the present application.

[0025] Please refer to Figure 1 and Figure 2 According to a first aspect of the present application, a blood pumping catheter assembly is provided, including a catheter 10 and a smooth layer. A perfusion passage 11 is formed inside the catheter 10. On the path of the perfusion passage 11, the side wall corresponding to the perfusion passage 11 is the first surface; the smooth layer is disposed on at least part of the first surface 12, and the surface roughness Ra of the smooth layer is less than the surface roughness of the first surface 12.

[0026] The catheter 10 may include a distal end and a proximal end. The distal end is the end where the catheter 10 intervenes in the human body, and the proximal end is the end where the catheter 10 is located outside the body. A perfusion passage 11 is formed inside the catheter 10. The perfusion passage 11 extends from the proximal end to the distal end, and a perfusion fluid is provided inside it. The perfusion fluid can prevent the patient's blood from flowing into the inside of the catheter 10, reduce the risk of thrombus formation inside the catheter 10, improve the reliability and service life of the catheter 10. At the same time, the perfusion fluid can also play a certain heat exchange role, exchanging heat with the catheter 10 and the external environment of the catheter 10.

[0027] It can be understood that the side wall corresponding to the perfusion passage 11 may be the inner wall of the catheter 10 facing the perfusion passage 11, that is, the inner wall of the catheter 10 for contacting the perfusion fluid; and / or, the side wall corresponding to the perfusion passage 11 may also be the side wall of other components provided in the perfusion passage 11 for contacting the perfusion fluid. It can be understood that the first surface may include any side wall in contact with the perfusion fluid inside the perfusion passage 11. It should be noted that the smooth layer is disposed on at least part of the first surface 12, that is, the smooth layer covers at least part of the first surface 12, and it can block the first surface 12 from contacting the perfusion fluid located in the perfusion passage 11, preventing the perfusion fluid from directly contacting the first surface 12. The smooth layer may be disposed on all of the first surface 12 or part of the first surface 12, and the present embodiment does not limit this. Of course, the catheter 10 may further include a second surface facing the external environment, which is disposed opposite to the first surface 12. It should be noted that the external environment refers to the environment outside the catheter 10. When the catheter 10 intervenes in the human body, the external environment may be the patient's internal environment and / or external environment.

[0028] In the embodiments of the present application, by providing a smooth layer on at least a part of the first surface 12, when the perfusion passage 11 is filled with perfusion fluid, the perfusion fluid can contact the smooth layer instead of contacting at least a part of the first surface 12. Since the surface roughness of the smooth layer is smaller than that of the first surface 12, the surface of the smooth layer is smoother relative to the first surface 12 and it is not easy to adhere to air bubbles. Therefore, it is beneficial to discharge the air bubbles in the perfusion passage 11 during pre-perfusion. On the one hand, it can reduce the risk of air embolism caused by air bubbles entering the patient's body and improve the safety performance. On the other hand, it can also improve the perfusion effect of the blood pump catheter and enhance the reliability of the catheter 10.

[0029] In some embodiments, the smooth layer is configured as a hydrophilic layer, and the surface of the hydrophilic layer can effectively absorb the moisture in the perfusion fluid. In this way, it can reduce the contact area between the air bubbles in the perfusion passage 11 and the surface of the smooth layer, further reducing the risk of the air bubbles in the perfusion passage 11 adhering to the surface of the smooth layer, and is more conducive to discharging the air bubbles in the perfusion passage 11 from the catheter 10.

[0030] In some alternative embodiments, the smooth layer is configured to expand under the infiltration of the perfusion fluid. Therefore, when the smooth layer is provided on the first surface 12 of the catheter 10, the smooth layer expands under the infiltration of the perfusion fluid, which can reduce the size of the gap communicating with the external environment on the catheter 10, thereby reducing the risk of thrombosis caused by external blood entering the inside of the catheter 10 through this gap.

[0031] In some embodiments, the surface roughness Ra of the first surface 12 satisfies: Ra < 0.5 micrometers.

[0032] In these embodiments, by reasonably setting the surface roughness of the first surface 12 of the catheter 10, the first surface 12 can be made relatively smooth. When the smooth layer covers a part of the first surface 12, it can reduce the risk of air bubbles adhering to the part of the first surface 12 that is not covered by the smooth layer, and is more conducive to discharging air bubbles.

[0033] Moreover, since the surface roughness of the smooth layer is smaller than that of the first surface 12, when the surface roughness of the first surface 12 is less than 0.5 micrometers, the surface roughness of the smooth layer is also less than 0.5 micrometers, thereby ensuring the performance of the smooth layer and reducing the risk of air bubbles adhering to the surface of the smooth layer.

[0034] Please continue to refer to Figure 1 and Figure 2, in some embodiments, the catheter 10 includes a first sub-tube 101 and a second sub-tube 102 sleeved on the outer peripheral side of the first sub-tube 101. A first sub-passage 111 is formed between the first sub-tube 101 and the second sub-tube 102, and a second sub-passage 112 is formed inside the first sub-tube 101. The first sub-passage 111 and the second sub-passage 112 are only connected at the distal end. The first sub-passage 111 and the second sub-passage 112 form a perfusion passage 11. The first surface 12 includes at least one of the surface of the first sub-tube 101 facing the first sub-passage 111, the surface of the first sub-tube 101 facing the second sub-passage 112, and the surface of the second sub-tube 102 facing the first sub-passage 111.

[0035] Specifically, one of the first sub-passage 111 and the second sub-passage 112 can be an injection passage, and the other can be a return passage. In this application, the case where the first sub-passage 111 is the injection passage and the second sub-passage 112 is the return passage is taken as an example for illustration.

[0036] The second sub-tube 102 is sleeved on the outer peripheral side of the first sub-tube 101, and the tube wall of the second sub-tube 102 is spaced from the tube wall of the first sub-tube 101, so that a first sub-passage 111 is formed between the tube wall of the first sub-tube 101 and the tube wall of the second sub-tube 102. At the same time, a second sub-passage 112 is also formed inside the first sub-tube 101. The first sub-passage 111 and the second sub-passage 112 can be connected to each other at the distal end. Therefore, after the perfusion component injects the perfusion fluid into the first sub-passage 111, the perfusion fluid in the first sub-passage 111 can flow to the distal end and then flow into the second sub-passage 112 and return through the second sub-passage 112, so that the perfusion fluid in the perfusion passage 11 is in a flowing state. On the one hand, it can improve the heat exchange effect between the perfusion fluid and the catheter 10 and the external environment of the catheter 10. On the other hand, the perfusion fluid can also carry away the impurity particles inside the catheter 10 during the flowing process, avoiding blockage of the catheter 10. It can be understood that if the first sub-passage 111 is the injection passage and the second sub-passage 112 is the return passage, since the first sub-passage 111 is located between the first sub-tube 101 and the second sub-tube 102, and the second sub-passage 112 is located inside the first sub-tube 101, the first sub-passage 111 is closer to the external environment of the catheter 10, and the second sub-passage 112 is farther from the external environment of the catheter 10. Compared with setting the second sub-passage 112 closer to the external environment of the catheter 10, it can improve the heat exchange effect between the perfusion fluid in the first sub-passage 111 and the catheter 10 and the external environment of the catheter 10, and can also reduce the risk that the impurity particles driven by the perfusion fluid during reflux flow into the human body through the tiny gaps formed on the catheter 10, improving safety.

[0037] It should be noted that a perfusion fluid inlet and a perfusion fluid outlet may also be formed on the catheter 10. Both the perfusion fluid inlet and the perfusion fluid outlet may be disposed near the proximal end of the catheter 10. Therefore, after injecting the perfusion fluid into the first sub-path 111 through the perfusion fluid inlet at the proximal end of the catheter 10, the perfusion fluid flows from the proximal end to the distal end in the first sub-path 111. After flowing to the distal end, it flows from the first sub-path 111 into the second sub-path 112 and flows from the distal end to the proximal end in the second sub-path 112, and finally flows out from the perfusion fluid outlet.

[0038] In addition, in these embodiments, the first surface 12 of the catheter 10 includes at least one of the surface of the first sub-tube 101 facing the first sub-path 111, the surface of the first sub-tube 101 facing the second sub-path 112, and the surface of the second sub-tube 102 facing the first sub-path 111. That is, a smooth layer is provided on at least one of the surface of the first sub-tube 101 facing the first sub-path 111, the surface of the first sub-tube 101 facing the second sub-path 112, and the surface of the second sub-tube 102 facing the first sub-path 111, which can reduce the bubble adsorption on the above surfaces and facilitate the discharge of the bubbles in the perfusion path 11. It should be noted that the first sub-path 111 is located between the tube walls of the first sub-tube 101 and the second sub-tube 102, and the second sub-path 112 is located inside the first sub-tube 101. Therefore, the surface of the first sub-tube 101 facing the first sub-path 111 is the outer surface of the first sub-tube 101, the surface of the first sub-tube 101 facing the second sub-path 112 is the inner surface of the first sub-tube 101, and the surface of the second sub-tube 102 facing the first sub-path 111 is the inner surface of the second sub-tube 102.

[0039] Please continue to refer to Figure 1 and Figure 2 In some embodiments, the blood pumping catheter assembly further includes an impeller rotating shaft 13. The impeller rotating shaft 13 is disposed at the distal end of the second sub-tube 102 and is used to connect to a motor. The first surface 12 further includes at least a part of the surface of the impeller rotating shaft 13 that contacts the perfusion fluid.

[0040] The impeller rotating shaft 13 is arranged at one end of the second sub-tube 102. Optionally, the impeller rotating shaft 13 can be embedded in the distal end of the second sub-tube 102, and part of the impeller rotating shaft 13 is located inside the catheter 10. It can contact the perfusion fluid in the first sub-passage 111 between the first sub-tube 101 and the second sub-tube 102, enabling the perfusion fluid in the first sub-passage 111 to exchange heat with the impeller rotating shaft 13. Of course, the impeller rotating shaft 13 can also be connected to the second sub-tube 102 in other ways, and this embodiment does not limit this. The impeller rotating shaft 13 is used to connect to the motor. When the catheter 10 is inserted into the human body, the impeller rotating shaft 13 is inside the body and can rotate driven by the motor to pump the blood in the aorta into the ventricle to assist the heart in working. Optionally, the motor can be located inside the catheter 10 or outside the catheter 10, and this embodiment does not limit this.

[0041] In these embodiments, the first surface 12 further includes at least part of the surface of the impeller rotating shaft 13 that contacts the perfusion fluid. That is to say, at least part of the surface of the impeller rotating shaft 13 that contacts the perfusion fluid is provided with a smooth layer, so as to reduce the risk of air bubbles adsorbing on the impeller rotating shaft 13 and is more conducive to the discharge of air bubbles.

[0042] It should be noted that the perfusion fluid can be a liquid with less impact on the human body such as glucose to avoid affecting the safety of the patient when the perfusion fluid leaks into the human body.

[0043] Please continue to refer to Figure 1 and Figure 2 , in some embodiments, the blood pumping catheter assembly further includes a drive shaft 14 and a bearing 15. At least part of the drive shaft 14 is located in the second sub-passage 112, the bearing 15 is located in the second sub-passage 112 and is sleeved on the drive shaft 14, and the first surface 12 includes at least part of the surface of the drive shaft 14 and / or the bearing 15 that contacts the perfusion fluid.

[0044] It should be noted that the drive shaft 14 can include a transmission rotating shaft and the above-mentioned impeller rotating shaft 13. The transmission rotating shaft is connected between the impeller rotating shaft 13 and the motor. Alternatively, the drive shaft 14 can also be an independent shaft body, which is connected to the impeller rotating shaft 13 and the motor, and this embodiment does not limit this.

[0045] In these embodiments, the bearing 15 is sleeved on the drive shaft 14, which can improve the stability of the drive shaft 14 during rotation. At least part of the drive shaft 14 is located in the second sub-passage 112, and the bearing 15 is located in the second sub-passage 112. Therefore, heat can be exchanged between the perfusion fluid and the drive shaft 14 and the bearing 15, and at the same time, the perfusion fluid in the second sub-passage 112 can also carry out the impurity particles generated during the operation of the drive shaft 14 and the bearing 15 out of the catheter 10, reducing the risk of the impurity particles entering the human body.

[0046] In addition, if at least a part of the drive shaft 14 and the bearing 15 are located in the second sub-passage 112, then the outer surface of at least a part of the drive shaft 14 and the outer surface of the bearing 15 will come into contact with the perfusion fluid in the second sub-passage 112. Therefore, the first surface 12 includes at least a part of the surface of the drive shaft 14 and / or the bearing 15 that comes into contact with the perfusion fluid, that is, the first surface 12 includes a part of the outer surface of the drive shaft 14 and / or at least a part of the outer surface of the bearing 15. Thus, by providing a smooth layer on a part of the outer surface of the drive shaft 14 and / or at least a part of the outer surface of the bearing 15, the risk of air bubbles in the perfusion passage 11 adhering to the drive shaft 14 and / or the bearing 15 can be reduced, which is more conducive to the discharge of air bubbles.

[0047] Please continue to refer to Figure 1 , in some alternative embodiments, the drive shaft 14 may include a first rotating shaft 141 and a second rotating shaft 142. The first rotating shaft 141 is connected to the impeller rotating shaft 13 and extends from the impeller rotating shaft 13 into the second sub-passage 112. The second rotating shaft 142 is connected to the first rotating shaft 141 in the second sub-passage 112 and extends proximally to the catheter 10 to be connected to the motor. The second rotating shaft 142 can be made of a flexible material, that is, the second rotating shaft 142 is a flexible shaft, so that the catheter 10 can be bent during the catheterization process to enter from one part of the human body into another part.

[0048] Please continue to refer to Figure 1 , in some embodiments, the first sub-tube 101 includes a tube body 103 and a bearing stop ring 104 connected to the tube body 103. The drive shaft 14 protrudes radially along its own axis to form a convex portion 143. The bearing stop ring 104 is arranged around the circumference of the drive shaft 14 and is spaced from the convex portion 143. The bearing 15 is located between the bearing stop ring 104 and the convex portion 143. The first surface 12 further includes at least a part of the surface of the tube body 103 and / or the bearing stop ring 104 facing the perfusion passage 11.

[0049] The bearing stop ring 104 can be located on one side of the tube body 103 close to the distal end of the catheter 10, and is arranged around the outer circumference of the drive shaft 14. In addition, the portion of the drive shaft 14 located in the second sub-passageway 112 can protrude along its own radial direction to form a convex portion 143. The convex portion 143 and the bearing stop ring 104 can be spaced apart along the axial direction of the drive shaft 14, so that the bearing 15 can be located between the bearing stop ring 104 and the convex portion 143, so as to limit the bearing 15 along the radial direction of the drive shaft 14 by the bearing stop ring 104 and the convex portion 143, thereby reducing the axial runout of the bearing 15 along the drive shaft 14 and improving stability. The surface of the tube body 103 and / or the bearing stop ring 104 facing the perfusion passage 11 may include the surface of the tube body 103 and / or the bearing stop ring 104 facing the first sub-passage 111 and the surface of the tube body 103 and / or the bearing stop ring 104 facing the second sub-passage 112. In the present embodiment, the first surface 12 is also provided to include at least a portion of the surface of the tube body 103 and / or the bearing stop ring 104 facing the perfusion passage 11, so that a smooth layer can be provided on at least a portion of the surface of the tube body 103 and / or the bearing stop ring 104 facing the perfusion passage 11, which can reduce the risk of bubbles adhering to the tube body 103 and / or the bearing stop ring 104 and is more conducive to the discharge of bubbles.

[0050] It should be noted that the bearing stop ring 104 is arranged around the circumference of the drive shaft 14, and a gap can be formed between the bearing stop ring 104 and the drive shaft 14. The first sub-passageway 111 and the second sub-passageway 112 can be connected through the gap, that is, the perfusion fluid in the first sub-passageway 111 can flow into the second sub-passageway 112 through the gap between the bearing stop ring 104 and the drive shaft 14, without the need to additionally set an opening for connecting the first sub-passageway 111 and the second sub-passageway 112.

[0051] It can be understood that if the bearing stop ring 104 and the drive shaft 14 are both provided with a smooth layer, when the smooth layer expands under the infiltration of the perfusion fluid, the size of the gap between the bearing stop ring 104 and the drive shaft 14 can be reduced, thereby reducing the risk of blood flowing into the second sub-channel 112 from the gap between the bearing stop ring 104 and the drive shaft 14 and generating thrombosis at the bearing 15 of the second sub-channel 112.

[0052] Please continue reading Figure 1In some embodiments, the tube body 103 includes a sheath tube 105, a first sealing cover 106 and a first connecting portion 107 which are connected in sequence along the axial direction of the drive shaft 14 toward the distal end, the bearing stop ring 104 is connected to the first connecting portion 107, the first sealing cover 106 and the bearing stop ring 104 are located on both sides of the bearing 15 along the axial direction of the drive shaft 14, the first connecting portion 107 is arranged on the side of the bearing 15 away from the drive shaft 14 along the radial direction of the drive shaft 14, and the first surface 12 also includes at least a portion of the surface of at least one of the sheath tube 105, the first sealing cover 106 and the first connecting portion 107 facing the perfusion passage 11.

[0053] Specifically, in the tube body 103, the sheath 105, the first sealing cover 106 and the first connecting part 107 can be connected in sequence from the proximal end of the catheter 10 to the distal end of the catheter 10, and the bearing stop ring 104 can be arranged close to the distal end of the catheter 10, which is connected to the first connecting part 107. Therefore, the bearing stop ring 104, the first connecting part 107, the first sealing cover 106 and the sheath 105 can jointly define the second sub-passage 112, and the bearing stop ring 104, the first connecting part 107, the first sealing cover 106, the sheath 105 and the first sub-tube 101 can jointly define the first sub-passage 111.

[0054] The first sealing cover 106 and the bearing stop ring 104 are located on both sides of the bearing 15 along the axial direction of the drive shaft 14, and the bearing 15 is located between the bearing stop ring 104 and the convex portion 143, and the first sealing cover 106 is located along the axial direction of the drive shaft 14 on the side of the convex portion 143 away from the bearing 15. The first connecting portion 107 is arranged on the side of the bearing 15 away from the drive shaft 14 along the radial direction of the drive shaft 14, and the axial position of the drive shaft 14 can be limited by the first connecting portion 107 along the radial direction of the drive shaft 14, so as to reduce the radial runout of the bearing 15 and the drive shaft 14, and further improve the stability of the bearing 15 and the drive shaft 14.

[0055] In addition, the first surface 12 also includes at least a portion of the surface of at least one of the sheath 105, the first sealing cover 106 and the first connecting part 107 facing the perfusion passage 11. A smooth layer can be provided on at least a portion of the surface of at least one of the sheath 105, the first sealing cover 106 and the first connecting part 107 facing the perfusion passage 11 to reduce the risk of bubbles adhering to at least one of the sheath 105, the first sealing cover 106 and the first connecting part 107.

[0056] Please continue reading Figure 1, in some embodiments, the second sub-tube 102 includes a tube body 108, a second connection portion 109, and a second sealing cover 110 that are connected in sequence. The tube body 108 is disposed around the circumference of the first sub-tube 101. The second sealing cover 110 is located on one side of the first sub-tube 101 along the axial direction of the first sub-tube 101. The first surface 12 further includes at least a part of the surface of at least one of the tube body 108, the second connection portion 109, and the second sealing cover 110 facing the perfusion passage 11.

[0057] In these embodiments, the tube body 108 can be disposed near the proximal end of the catheter 10, and the second sealing cover 110 can be disposed near the distal end of the catheter 10. The tube body 108, the second connection portion 109, the second sealing cover 110, and the first sub-tube 101 can define a first sub-passage 111. The first surface 12 further includes at least a part of the surface of at least one of the tube body 108, the second connection portion 109, and the second sealing cover 110 facing the perfusion passage 11, so that a smooth layer can be provided on at least a part of the surface of at least one of the tube body 108, the second connection portion 109, and the second sealing cover 110 facing the perfusion passage 11 to reduce the risk of air bubbles adhering to at least one of the tube body 108, the second connection portion 109, and the second sealing cover 110.

[0058] It should be noted that when the blood pumping catheter assembly includes the impeller rotating shaft 13, the impeller rotating shaft 13 can be embedded in the second sealing cover 110, and a gap can be formed between it and the second sealing cover 110. The perfusion liquid in the first sub-passage 111 can flow into the human body through this gap.

[0059] It can be understood that since there is perfusion liquid in the gap between the second sealing cover 110 and the impeller rotating shaft 13, this gap can also be equivalent to a part of the perfusion passage 11. Then the first surface 12 includes the surface of the second sealing cover 110 facing this gap. Therefore, a smooth layer can be provided on the surface of the second sealing cover 110 facing this gap. When the smooth layer is wetted by the perfusion liquid and collides, the size of this gap can be reduced, thereby reducing the risk of blood flowing into the inside of the catheter 10 through this gap.

[0060] The second aspect of the present application provides a ventricular assist device, including the blood pumping catheter assembly of any one of the above. The ventricular assist device provided by the embodiments of the present application has the technical effects of the technical solutions of the blood pumping catheter assembly in any one of the above embodiments. The same or corresponding structures and the explanations of terms are not repeated here.

[0061] As described above, this is only the specific implementation manner of the present application. Those skilled in the art can clearly understand that for the convenience and brevity of description, the specific working processes of the systems, modules, and units described above can refer to the corresponding processes in the foregoing method embodiments, and will not be elaborated herein. It should be understood that the protection scope of the present application is not limited thereto. Any person skilled in the art within the technical scope disclosed by the present application can easily think of various equivalent modifications or substitutions, and these modifications or substitutions should all be covered within the protection scope of the present application.

Claims

1. A blood pumping catheter assembly, characterized in that, include: A catheter, wherein a perfusion passage is formed in the catheter, and on the path of the perfusion passage, a side wall corresponding to the perfusion passage is a first surface; A smooth layer is disposed on at least a portion of the first surface, and the surface roughness of the smooth layer is smaller than the surface roughness of the first surface.

2. The blood pumping catheter assembly according to claim 1, wherein, The smooth layer is configured as a hydrophilic layer.

3. The blood pumping catheter assembly according to claim 1, wherein, The surface roughness Ra of the smooth layer satisfies: Ra<0.5 micrometer.

4. The blood pumping catheter assembly according to any one of claims 1-3, characterized in that, The catheter includes a first sub-tube and a second sub-tube sleeved on the outer circumference of the first sub-tube, a first sub-passageway is formed between the first sub-tube and the second sub-tube, a second sub-passageway is formed inside the first sub-tube, the first sub-passageway and the second sub-passageway are connected only at the distal end, the first sub-passageway and the second sub-passageway together form the perfusion passage, and the first surface includes at least one of a surface of the first sub-tube facing the first sub-passageway, a surface of the first sub-tube facing the second sub-passageway, and a surface of the second sub-tube facing the first sub-passageway.

5. The blood pumping catheter assembly according to claim 4, wherein The blood pumping catheter assembly further includes an impeller shaft, which is disposed at the distal end of the second sub-tube and is used to be connected to a motor. The first surface further includes at least a portion of the surface of the impeller shaft that contacts the perfusion fluid.

6. The blood pumping catheter assembly according to claim 4, wherein, The blood pumping catheter assembly also includes a driving shaft and a bearing, at least part of the driving shaft is located in the second sub-passageway, the bearing is located in the second sub-passageway and is sleeved on the driving shaft, and the first surface includes at least part of the surface on the driving shaft and / or the bearing that is in contact with the perfusion fluid.

7. The blood pumping catheter assembly according to claim 6, wherein, The first sub-tube includes a tube body and a bearing stop ring connected to the tube body, the drive shaft is radially extended to form a convex portion, the bearing stop ring is circumferentially arranged around the drive shaft and spaced apart from the convex portion, the bearing is located between the bearing stop ring and the convex portion, and the first surface also includes at least a portion of the surface of the tube body and / or the bearing stop ring facing the perfusion passage.

8. The blood pumping catheter assembly according to claim 7, wherein, The tube body includes a sheath tube, a first sealing cover and a first connecting portion which are connected in sequence along the axial direction of the drive shaft toward the distal end, the bearing stop ring is connected to the first connecting portion, the first sealing cover and the bearing stop ring are located on both sides of the bearing along the axial direction of the drive shaft, the first connecting portion is arranged on the side of the bearing away from the drive shaft along the radial direction of the drive shaft, and the first surface also includes at least a partial surface of at least one of the sheath tube, the first sealing cover and the first connecting portion facing the perfusion passage.

9. The blood pumping catheter assembly according to claim 4, wherein The second sub-tube includes a tube body, a second connecting portion and a second sealing cover connected in sequence, the second sealing cover is located on one side of the first sub-tube along the axial direction of the first sub-tube, and the first surface also includes at least a partial surface of at least one of the tube body, the second connecting portion and the second sealing cover facing the perfusion passage.

10. A ventricular assist device, characterized in that, A blood pumping catheter assembly comprising any one of claims 1-9.

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