Efficient multi-stage separation and purification equipment for yeast polypeptide

Abstract

The utility model provides efficient multistage separation and purification equipment for yeast polypeptide, which comprises a purification equipment box, the top of the purification equipment box is fixedly connected with a first servo motor, and an output shaft of the first servo motor is fixedly connected with a rotating rod. A plurality of stirring rods which are distributed at equal intervals and are the same in size are fixedly connected to the left side and the right side of the rotating rod, a cleaning mechanism is arranged on the back side of the purification equipment box, and the cleaning mechanism comprises a second servo motor, a rotating disc, a rotating block, a first swing rod, a second swing rod, a moving rod and a cleaning plate. A heating layer is arranged in an inner cavity of the purification equipment box, by arranging the cleaning mechanism, the top of the filter screen can be conveniently cleaned, the situation that the top of the filter screen is blocked, and consequently separated and purified solutions cannot normally flow out through a discharging pipe is avoided, meanwhile, the situation that people repeatedly and manually clean the filter screen is avoided, and the working efficiency is improved.

Description

Technical Field

[0001] The utility model relates to a high - efficiency multi - stage separation and purification device for yeast polypeptides, belonging to the technical field of polypeptide separation and purification. Background Technique

[0002] A peptide is a compound formed by connecting α - amino acids with peptide bonds. It is an intermediate product of protein hydrolysis. A compound formed by dehydration condensation of two amino acid molecules is called a dipeptide. By the same token, there are also tripeptides, tetrapeptides, pentapeptides, etc. A peptide composed of three or more amino acid molecules is called a polypeptide.

[0003] Chinese Patent (Publication No.: CN 220443635 U) discloses a polypeptide preparation and purification device, including a fixed bracket. A purification equipment box is installed at the top of the fixed bracket. A feed inlet is opened on one side of the top of the purification equipment box. An air outlet is arranged outside the upper part of the purification equipment box. A discharge port is arranged at the middle position of the bottom of the purification equipment box. A stirring structure for improving the purification efficiency is arranged inside the purification equipment box. The heating layer is used to heat the solution inside the equipment box, making the solution heat more evenly, and also facilitating the gasification of impurities and moisture in the solution, improving the purification effect and quality of the polypeptide.

[0004] Through the above - mentioned patent, by setting the stirring structure, the solution can be heated more evenly, improving the purification effect of the polypeptide. However, in actual use, the solution after the reaction needs to be filtered through a filter screen and then discharged. In this process, the filter screen is very easy to be blocked, and people need to manually disassemble and clean the filter screen, with relatively low work efficiency. Moreover, after being blocked, it will also affect the discharge of the solution, which is not conducive to people's use.

[0005] Therefore, a high - efficiency multi - stage separation and purification device for yeast polypeptides is proposed. Content of the Utility Model

[0006] In view of this, the utility model provides a high - efficiency multi - stage separation and purification device for yeast polypeptides to solve or alleviate the technical problems existing in the prior art, and at least provide a beneficial choice.

[0007] The technical solution of the utility model is realized as follows: A high - efficiency multi - stage separation and purification device for yeast polypeptides, including a purification equipment box. A first servo - motor is fixedly connected to the top of the purification equipment box. The output shaft of the first servo - motor is fixedly connected to a rotating rod. A plurality of equally - spaced and same - sized stirring rods are fixedly connected to both the left and right sides of the rotating rod. A cleaning mechanism is arranged on the back side of the purification equipment box. The cleaning mechanism includes a second servo - motor, a rotating disk, a rotating block, a first swing rod, a second swing rod, a moving rod and a cleaning plate. A heating layer is arranged in the inner cavity of the purification equipment box.

[0008] Further preferably, the second servo motor is fixedly connected to the back side of the purification equipment box, the rotating disk is arranged inside the purification equipment box and below the rotating rod, and the back side of the rotating disk is fixedly connected to the output shaft of the second servo motor. The rotating block is fixedly connected to the front side of the rotating disk. The first swing rod is arranged on the front side of the rotating disk. The top of the back side of the first swing rod is movably connected to the back side of the inner cavity of the purification equipment box through a rotating shaft, and the rotating block is slidably connected to the inner side of the first swing rod. The second swing rod is arranged on the front side of the first swing rod, and the back side of the second swing rod is movably connected to the front side of the first swing rod through a rotating shaft. The moving rod is arranged on the back side of the second swing rod, and the front side of the moving rod is movably connected to the back side of the second swing rod through a rotating shaft. The cleaning plate is fixedly connected to the right side of the front side of the moving rod.

[0009] Further preferably, a feed pipe is communicated above the top of the purification equipment box and in front of the first servo motor, and a discharge pipe is communicated with the bottom of the purification equipment box. Sealing covers are connected to the outer sides of the feed pipe and the discharge pipe through threads.

[0010] Further preferably, connecting rods are fixedly connected to the left and right sides of the top of the inner cavity of the purification equipment box, and a plurality of equally spaced and same-sized flow disturbing rods are fixedly connected to the inner sides of the connecting rods.

[0011] Further preferably, fixing frames are fixedly connected to the left and right sides of the inner cavity of the purification equipment box. A filter disk is arranged inside the fixing frames. A slot is formed in the front side of the purification equipment box, and the filter disk is slidably connected to the inside of the slot. A sealing ring is arranged on the outer surface of the front side of the filter disk, and the outer surface of the sealing ring is closely attached to the inside of the slot.

[0012] Further preferably, a limiting plate is fixedly connected to the back side of the bottom of the inner cavity of the purification equipment box, and the moving rod is slidably connected to the inside of the limiting plate.

[0013] Further preferably, a discharge slot is formed in the right side of the purification equipment box, and a baffle is hinged to the right side of the discharge slot through a spring positioning hinge.

[0014] Further preferably, a filter screen is arranged at the top of the discharge pipe, and the filter screen is embedded and installed above the inside of the discharge pipe. At the same time, the structure between the bottom middle of the discharge pipe and the purification equipment box is detachable.

[0015] Due to the adoption of the above technical solutions in the embodiments of the present utility model, it has the following advantages:

[0016] 1. The utility model is provided with a cleaning mechanism, which can facilitate the cleaning of the top of the filter screen, avoid the blockage of the top of the filter screen, prevent the solution after separation and purification from flowing out of the discharge pipe normally, and also avoid manual cleaning of the filter screen by people repeatedly, thus improving work efficiency.

[0017] 2. The utility model is provided with a sealing cover, which can prevent external impurities from entering the inner cavity of the purification equipment box through the feed pipe and the discharge pipe. By setting a connecting rod and a spoiler rod, a spoiler effect can be formed to avoid uneven mixing of the solution due to inertia during the stirring process. By setting a filter disc, a separation effect can be achieved to separate the mixed solution for the first time. And by setting a slot, it is also convenient to draw out the filter disc for cleaning or replacement. By setting a limiting plate, it can limit the movement of the moving rod. By setting a discharge groove, it is convenient for the cleaning plate to push the residue out of the inner cavity of the purification equipment box through the discharge groove. By setting a filter screen, a secondary separation effect can be achieved to further improve the purity of the solution.

[0018] The above summary is only for the purpose of the specification and is not intended to be limiting in any way. In addition to the above-described illustrative aspects, embodiments and features, further aspects, embodiments and features of the present utility model will be readily apparent by reference to the drawings and the following detailed description. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] In order to more clearly illustrate the technical solutions in the embodiments of the present application or the prior art, the following will briefly introduce the drawings required for the description of the embodiments or the prior art. Obviously, the following drawings are only some embodiments of the present application. For those of ordinary skill in the art, other drawings can be obtained based on these drawings without creative efforts.

[0020] Figure 1 It is a front view structural schematic diagram of the main body of the present utility model;

[0021] Figure 2 It is a sectional view structural schematic diagram of the purification equipment box of the present utility model;

[0022] Figure 3 It is a front view structural schematic diagram of the purification equipment box of the present utility model;

[0023] Figure 4 It is a structural schematic diagram of the cleaning mechanism of the present utility model in a disassembled state;

[0024] Figure 5 It is a right side view structural schematic diagram of the purification equipment box of the present utility model;

[0025] Figure 6This is a schematic structural diagram of the filter disc of the present utility model in a disassembled state.

[0026] Reference numerals: 1, purification equipment box; 2, first servo motor; 3, rotating rod; 4, stirring rod; 5, cleaning mechanism; 501, second servo motor; 502, rotating disc; 503, rotating block; 504, first swinging rod; 505, second swinging rod; 506, moving rod; 507, cleaning plate; 6, feed pipe; 7, discharge pipe; 8, sealing cover; 9, connecting rod; 10, flow disturbing rod; 11, fixing frame; 12, filter disc; 13, slot; 14, sealing ring; 15, limiting plate; 16, discharge chute; 17, baffle; 18, filter net; 19, heating layer. Detailed implementation manners

[0027] In the following, only some exemplary embodiments are simply described. As those skilled in the art can recognize, the described embodiments can be modified in various different ways without departing from the spirit or scope of the present utility model. Therefore, the drawings and the description are considered to be exemplary in nature rather than restrictive.

[0028] The embodiments of the present utility model will be described in detail below with reference to the drawings.

[0029] Embodiment 1

[0030] As Figures 1-6As shown in the figure, an embodiment of the present utility model provides a high-efficiency multi-stage separation and purification device for yeast polypeptides, including a purification device box 1. A first servo motor 2 is fixedly connected to the top of the purification device box 1. The output shaft of the first servo motor 2 is fixedly connected to a rotating rod 3. A plurality of equally spaced and identically sized stirring rods 4 are fixedly connected to both the left and right sides of the rotating rod 3. A cleaning mechanism 5 is arranged on the back side of the purification device box 1. The cleaning mechanism 5 includes a second servo motor 501, a rotating disk 502, a rotating block 503, a first swing rod 504, a second swing rod 505, a moving rod 506, and a cleaning plate 507. A heating layer 19 is arranged in the inner cavity of the purification device box 1. The second servo motor 501 is fixedly connected to the back side of the purification device box 1. The rotating disk 502 is arranged in the inner cavity of the purification device box 1 and is located below the rotating rod 3, and the back side of the rotating disk 502 is fixedly connected to the output shaft of the second servo motor 501. The rotating block 503 is fixedly connected to the front side of the rotating disk 502. The first swing rod 504 is arranged on the front side of the rotating disk 502. The top of the back side of the first swing rod 504 is movably connected to the back side of the inner cavity of the purification device box 1 through a rotating shaft, and the rotating block 503 is slidably connected to the inner side of the first swing rod 504. The second swing rod 505 is arranged on the front side of the first swing rod 504, and the back side of the second swing rod 505 is movably connected to the front side of the first swing rod 504 through a rotating shaft. The moving rod 506 is arranged on the back side of the second swing rod 505, and the front side of the moving rod 506 is movably connected to the back side of the second swing rod 505 through a rotating shaft. The cleaning plate 507 is fixedly connected to the right side of the front side of the moving rod 506.

[0031] By setting the cleaning mechanism 5, it is convenient to clean the top of the filter screen 18, avoiding the blockage of the top of the filter screen 18, which may cause the solution after separation and purification to not flow out normally through the discharge pipe 7. At the same time, it also avoids people manually cleaning the filter screen 18 repeatedly, improving work efficiency.

[0032] Embodiment 2

[0033] In one embodiment, a feed pipe 6 is connected to the top of the purification equipment box 1 and is located on the front side of the first servo motor 2. A discharge pipe 7 is connected to the bottom of the purification equipment box 1. Sealing caps 8 are threadedly connected to the outer sides of both the feed pipe 6 and the discharge pipe 7. On the left and right sides of the top inside the purification equipment box 1, connecting rods 9 are fixedly connected. Inside the connecting rods 9, a plurality of equally spaced and identically sized flow disturbing rods 10 are fixedly connected. On the left and right sides inside the purification equipment box 1, fixing frames 11 are fixedly connected. A filter disc 12 is arranged inside the fixing frames 11. A slot 13 is formed on the front side of the purification equipment box 1, and the filter disc 12 is slidably connected to the inside of the slot 13. A sealing ring 14 is arranged on the outer surface of the front side of the filter disc 12, and the outer surface of the sealing ring 14 is in close fit with the inside of the slot 13. A limiting plate 15 is fixedly connected to the back side of the bottom inside the purification equipment box 1, and the moving rod 506 is slidably connected to the inside of the limiting plate 15. A discharge slot 16 is formed on the right side of the purification equipment box 1. A baffle 17 is hinged to the right side of the discharge slot 16 through a spring positioning hinge. A filter net 18 is arranged on the top of the discharge pipe 7, and the filter net 18 is embedded and installed above the inside of the discharge pipe 7. At the same time, a detachable structure is provided between the middle of the bottom of the discharge pipe 7 and the purification equipment box 1.

[0034] By providing the sealing cap 8, it is possible to prevent external impurities from entering the inner cavity of the purification equipment box 1 through the feed pipe 6 and the discharge pipe 7. By providing the connecting rod 9 and the flow disturbing rod 10, a flow disturbing effect can be formed to prevent the solution from being insufficiently mixed due to inertia during the stirring process. By providing the filter disc 12, a separation effect can be achieved to perform the first separation on the mixed solution. And by providing the slot 13, it is also convenient to pull out the filter disc 12 for cleaning or replacement. By providing the limiting plate 15, it can limit the movement of the moving rod 506. By providing the discharge slot 16, it is convenient for the cleaning plate 507 to push the residue out of the inner cavity of the purification equipment box 1 through the discharge slot 16. By providing the filter net 18, a secondary separation effect can be achieved to further improve the purity of the solution.

[0035] When the utility model works: First, put the yeast polypeptide raw material to be separated and purified and the reaction solution into the inner cavity of the purification equipment box 1 through the feed pipe 6. At this time, start the first servo motor 2, drive the rotating rod 3 and the stirring rod 4 to rotate through the output shaft of the first servo motor 2, stir and mix the yeast polypeptide raw material and the reaction solution, and accelerate the reaction speed between the two through the heating of the heating layer 19. The purified solution is first filtered through the filter disc 12 and then filtered through the filter net 18 for the second time. During the second filtration process, the second servo motor 501 can be started, and the output shaft of the second servo motor 501 drives the rotating disc 502 to rotate. The rotating disc 502 drives the rotating block 503 to rotate, and during the rotation of the rotating block 503, it drives the first swing rod 504 to swing. The first swing rod 504 drives the second swing rod 505 to swing, thereby driving the moving rod 506 and the cleaning plate 507 to move left and right to clean the top of the baffle 17, preventing the top of the baffle 17 from being blocked by impurities in the solution, resulting in the solution being unable to be separated normally. Finally, the separated solution flows out through the discharge pipe 7, and then the filter disc 12 is taken out and the inside of the filter disc 12 is cleaned.

[0036] The above is only the specific implementation manner of the present utility model, but the protection scope of the present utility model is not limited thereto. Any person skilled in the art within the technical scope disclosed by the present utility model can easily think of various changes or substitutions thereof, and these should all be covered by the protection scope of the present utility model. Therefore, the protection scope of the present utility model should be subject to the protection scope of the claims.

Claims

1. An efficient multi-stage separation and purification device for yeast polypeptides, comprising a purification device box (1), characterized in that: A first servo motor (2) is fixedly connected to the top of the purification equipment box (1). The output shaft of the first servo motor (2) is fixedly connected to a rotating rod (3). On both the left and right sides of the rotating rod (3), a plurality of equally spaced and identical stirring rods (4) are fixedly connected. A cleaning mechanism (5) is arranged on the back side of the purification equipment box (1). The cleaning mechanism (5) includes a second servo motor (501), a rotating disk (502), a rotating block (503), a first swing rod (504), a second swing rod (505), a moving rod (506) and a cleaning plate (507). A heating layer (19) is arranged in the inner cavity of the purification equipment box (1).

2. The high-efficiency multi-stage separation and purification equipment for yeast polypeptides according to claim 1, wherein: The second servo motor (501) is fixedly connected to the back side of the purification equipment box (1). The rotating disk (502) is arranged in the inner cavity of the purification equipment box (1) and is located below the rotating rod (3). The back side of the rotating disk (502) is fixedly connected to the output shaft of the second servo motor (501). The rotating block (503) is fixedly connected to the front side of the rotating disk (502). The first swing rod (504) is arranged on the front side of the rotating disk (502). The top of the back side of the first swing rod (504) is movably connected to the back side of the inner cavity of the purification equipment box (1) through a rotating shaft. The rotating block (503) is slidably connected to the inner side of the first swing rod (504). The second swing rod (505) is arranged on the front side of the first swing rod (504). The back side of the second swing rod (505) is movably connected to the front side of the first swing rod (504) through a rotating shaft. The moving rod (506) is arranged on the back side of the second swing rod (505). The front side of the moving rod (506) is movably connected to the back side of the second swing rod (505) through a rotating shaft. The cleaning plate (507) is fixedly connected to the right side of the front side of the moving rod (506).

3. The high-efficiency multi-stage separation and purification equipment for yeast polypeptides according to claim 1, wherein: A feed pipe (6) is communicated with the top of the purification equipment box (1) and is located in front of the first servo motor (2). A discharge pipe (7) is communicated with the bottom of the purification equipment box (1). Sealing covers (8) are threadedly connected to the outer sides of the feed pipe (6) and the discharge pipe (7).

4. The high-efficiency multi-stage separation and purification equipment for yeast polypeptides according to claim 1, characterized in that: Connecting rods (9) are fixedly connected to both the left and right sides of the top of the inner cavity of the purification equipment box (1). A plurality of equally spaced and identical flow disturbing rods (10) are fixedly connected to the inner sides of the connecting rods (9).

5. The high-efficiency multi-stage separation and purification equipment for yeast polypeptides according to claim 1, wherein: Fixed frames (11) are fixedly connected to both the left and right sides of the inner cavity of the purification equipment box (1). A filter disk (12) is arranged inside the fixed frames (11). A slot (13) is formed in the front side of the purification equipment box (1). The filter disk (12) is slidably connected to the inside of the slot (13). A sealing ring (14) is arranged on the outer surface of the front side of the filter disk (12). The outer surface of the sealing ring (14) is closely attached to the inside of the slot (13).

6. The high-efficiency multi-stage separation and purification equipment for yeast polypeptides according to claim 2, characterized in that: A limiting plate (15) is fixedly connected to the back side of the bottom inside the purification equipment box (1), and the moving rod (506) is slidably connected to the inside of the limiting plate (15).

7. The high-efficiency multi-stage separation and purification equipment for yeast polypeptides according to claim 1, wherein: A discharge chute (16) is formed on the right side of the purification equipment box (1), and a baffle plate (17) is hinged to the right side of the discharge chute (16) through a spring positioning hinge.

8. An efficient multi-stage separation and purification device for yeast polypeptides according to claim 3, characterized in that: A filter screen (18) is arranged on the top of the discharge pipe (7), and the filter screen (18) is embedded and installed above the inside of the discharge pipe (7). At the same time, a detachable structure is provided between the middle of the bottom of the discharge pipe (7) and the purification equipment box (1).

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