Structure for heating and ionizing sample target through matrix-assisted spark discharge

Abstract

The utility model belongs to the technical field of mass spectrometry, and particularly relates to a structure of a matrix-assisted spark discharge heating ionization sample target, which comprises a target body, a gas input mechanism and a base, the target body is placed on the base, the gas input mechanism is arranged below the base, and a circular positioning groove is formed, so that the gas input mechanism is positioned in the circular positioning groove. Detection personnel can determine the position of a dropwise added sample conveniently, the sample is prevented from deviating from the discharge position of a probe, the detection efficiency is improved, the circular air holes are formed around the circular positioning groove in the center of the target body, input nitrogen flows out of the circular air holes, rapid drying of the sample can be assisted, ionization evaporation of the sample can be assisted, and sample oxidation is avoided; and the mass spectrum detection signal intensity is improved.

Description

Technical Field

[0001] The utility model relates to the technical field of mass spectrometry analysis, in particular to a structure of a matrix-assisted spark discharge heating ionization sample target. Background Technique

[0002] Mass spectrometry analysis is an analytical method for measuring the mass-to-charge ratio of ions. A substance needs to be ionized before mass spectrometry analysis can be carried out. The ion source of a mass spectrometer is the place where the sample is ionized. Its main function is to ionize neutral atoms or molecules into ions and form an ion beam with a certain energy. The ionization efficiency of the sample ions will have an important impact on the sensitivity and resolution of the mass spectrometer. Different ion sources have different performances due to different ionization methods. Although the spark discharge ion source has the advantages of high sensitivity, simple pretreatment, and less sample consumption, and is especially suitable for the analysis of metals and semiconductors; when used for the analysis of organic compounds, since organic compounds usually exist in liquid or powder states, and many organic compounds also have thermal sensitivity, during sample pretreatment, the organic compound to be measured is usually prepared into a mixed solution with a matrix (such as sinapic acid, cinnamic acid, etc.) and placed on the sample target. After the sample is dried, the heat energy generated by the spark discharge is used to vaporize and ionize it, and then detection is carried out.

[0003] The existing spark discharge ionization sample target has the following problems: Since the sample target is a smooth plane, when dropping liquid samples, it is not easy to position, and the sample often deviates from the position of the probe, which will affect the ionization effect and the number of repeated detections has to be increased; the drying time of the sample is slow, especially for samples that are not easy to volatilize, the drying often exceeds 5 minutes, which greatly affects the sample detection efficiency; although the spark discharge heating method is faster than the resistance heating method, the vaporization and evaporation speed of organic compound molecules that are not easy to volatilize is still not fast enough, affecting the ionization efficiency of such samples.

[0004] In order to solve the above problems, the utility model provides a matrix-assisted spark discharge heating ionization sample target here. Content of the Utility Model

[0005] The purpose of this part is to outline some aspects of the embodiments of the utility model and briefly introduce some preferred embodiments. In this part, as well as in the abstract of the specification and the title of the utility model of this application, some simplifications or omissions may be made to avoid obscuring the purpose of this part, the abstract of the specification, and the title of the utility model, and such simplifications or omissions cannot be used to limit the scope of the utility model.

[0006] In view of the above and / or problems existing in the existing mass spectrometry analysis, the present utility model is proposed.

[0007] Therefore, the object of the present utility model is to provide a structure of a matrix-assisted spark discharge heating and ionizing sample target. By providing a circular positioning groove, it is convenient for the detection personnel to determine the position of the added sample, prevent the sample from deviating from the probe discharge position, and improve the detection efficiency. By providing circular air holes around the circular positioning groove at the center of the target body, the input nitrogen gas flows out from the circular air holes, which can not only assist in the rapid drying of the sample, but also assist in the ionization and evaporation of the sample, avoid sample oxidation, and improve the mass spectrometry detection signal intensity.

[0008] To solve the above technical problems, according to one aspect of the present utility model, the following technical solutions are provided:

[0009] A structure of a matrix-assisted spark discharge heating and ionizing sample target, which includes: a target body, a gas input mechanism and a base. The target body is placed on the base, the gas input mechanism is arranged below the base, and the target body is provided with a circular positioning groove, circular air holes and a cavity. A circular positioning groove is provided at the center of the top of the target body, a cavity is arranged inside the target body, and circular air holes are arranged at the circumferential position outside the circular positioning groove.

[0010] As a preferred solution of the structure of a matrix-assisted spark discharge heating and ionizing sample target according to the present utility model, wherein: the gas input mechanism includes a sealing component, a first screw, a second screw and an air delivery pipe. The left and right sides of the sealing component are respectively provided with the first screw and the second screw connected to the target body, and an air delivery pipe communicating with the cavity is arranged at the bottom of the sealing component.

[0011] As a preferred solution of the structure of a matrix-assisted spark discharge heating and ionizing sample target according to the present utility model, wherein: the circular air holes are evenly distributed on the circumferential outside of the circular positioning groove.

[0012] As a preferred solution of the structure of a matrix-assisted spark discharge heating and ionizing sample target according to the present utility model, wherein: the upper surface of the target body is a spherical curved surface.

[0013] Compared with the prior art: By providing a circular positioning groove, the present utility model is convenient for the detection personnel to determine the position of the added sample, prevent the sample from deviating from the probe discharge position, and improve the detection efficiency. By providing circular air holes around the circular positioning groove at the center of the target body, the input nitrogen gas flows out from the circular air holes, which can not only assist in the rapid drying of the sample, but also assist in the ionization and evaporation of the sample, avoid sample oxidation, and improve the mass spectrometry detection signal intensity. Description of the Drawings

[0014] To more clearly illustrate the technical solutions of the embodiments of the present utility model, the present utility model will be described in detail below in conjunction with the drawings and detailed embodiments. Obviously, the drawings in the following description are only some embodiments of the present utility model. For those of ordinary skill in the art, without creative efforts, other drawings can be obtained based on these drawings. Among them:

[0015] Figure 1 It is a schematic axonometric structure diagram of the present utility model;

[0016] Figure 2 It is a schematic main cross-sectional structure diagram of the present utility model;

[0017] Figure 3 It is a schematic surface structure diagram of the target body of the present utility model.

[0018] In the figure: 1 target body, 11 circular positioning grooves, 12 circular air holes, 13 cavity, 2 gas input mechanism, 21 sealing component, 22 screw one, 23 screw two, 24 gas pipeline, 3 base. Specific embodiments

[0019] To make the above-mentioned objects, features and advantages of the present utility model more obvious and understandable, the specific embodiments of the present utility model will be described in detail below in conjunction with the drawings.

[0020] Many specific details are set forth in the following description in order to fully understand the present utility model, but the present utility model can also be implemented in other ways different from those described herein. Those skilled in the art can make similar generalizations without departing from the connotation of the present utility model. Therefore, the present utility model is not limited by the specific embodiments disclosed below.

[0021] Secondly, the present utility model is described in detail in conjunction with the schematic diagrams. When describing the embodiments of the present utility model in detail, for the convenience of explanation, the cross-sectional views showing the device structure will be enlarged locally not in accordance with the general ratio, and the schematic diagrams are only examples, which should not limit the protection scope of the present utility model herein. In addition, in actual production, three-dimensional spatial dimensions including length, width and depth should be included.

[0022] To make the purpose, technical solutions and advantages of the present utility model clearer, the embodiments of the present utility model will be further described in detail below in conjunction with the drawings.

[0023] The present utility model provides a structure for a matrix-assisted spark discharge heating and ionizing sample target. By arranging circular air holes around the circular positioning groove in the center of the target body, the input nitrogen gas flows out from the circular air holes, which can not only assist in the rapid drying of the sample, but also assist in the ionization and evaporation of the sample, avoid sample oxidation, and improve the mass spectrometry detection signal intensity. Please refer to Figures 1 - 3, including: a target body 1, a gas input mechanism 2 and a base 3.

[0024] The target body 1 is used to place the sample to be tested and perform spark discharge ionization. The gas input mechanism 2 is tightly connected to the target body 1 for nitrogen delivery. The base 3 is connected to the target body 1 to support the target body.

[0025] The target body 1 is provided with a circular positioning groove 11 for placing the sample. The purpose of this arrangement is to facilitate the detection personnel to drop the sample at a certain position on the target body.

[0026] A circular air hole 12 is provided around the circular positioning groove 11. The purpose of this arrangement is to facilitate the passage of nitrogen, which can assist in the drying and gasification evaporation of the sample.

[0027] A cavity 13 is provided under the circular positioning groove 11 and the circular air hole 12, and the purpose of this arrangement is to serve as a passage for nitrogen gas to flow through.

[0028] The upper end of the gas input mechanism 2 connects the sealing assembly 21 to the target body 1 through the screw 1 22 and the screw 2 23. The purpose of this arrangement is to make the gas input mechanism 2 and the target body 1 tightly connected to facilitate nitrogen transmission; the lower end is provided with a gas delivery pipe 24. The purpose of this arrangement is to introduce exogenous nitrogen into the cavity 13 of the target body;

[0029] like Figure 2 As shown, the upper surface of the target 1 is a spherical curved surface, and the purpose of this setting is to facilitate the volatilization and ionization of the sample assisted by nitrogen.

[0030] In specific use, the matrix-assisted spark discharge heats and ionizes the sample target. When the sample is tested, nitrogen is first introduced from the gas pipe 24, and the nitrogen gas flows through the gas pipe 24, the cavity 13, and the circular air hole 12 to be discharged. The nitrogen gas flow rate is adjusted, and then the mixed solution of the sample and the matrix is dripped into the circular positioning groove 11 in the center of the target body. The nitrogen gas flow quickly evaporates the sample solution to be tested to dryness. The nitrogen gas input state is maintained, and the sample target is energized to generate spark discharge with the probe. The organic compound molecules to be tested are quickly vaporized together with the matrix with the assistance of the nitrogen gas flow. The matrix transfers protons to the organic compound molecules to be tested for ionization. The organic compound ions to be tested are detected by a mass spectrometer detector, and finally the obtained mass spectrum data are analyzed.

[0031] Although the present utility model has been described above with reference to the embodiments, various improvements can be made thereto and components thereof can be replaced with equivalents without departing from the scope of the present utility model. In particular, as long as there is no structural conflict, the features in the embodiments disclosed by the present utility model can be combined with each other in any way, and the exhaustive description of these combinations is not given in this specification only for the consideration of saving space and resources. Therefore, the present utility model is not limited to the specific embodiments disclosed in the text, but includes all technical solutions falling within the scope of the claims.

Claims

1. Structure of a matrix-assisted spark discharge heated ionization sample target, characterized in that, Including: A target body (1), a gas input mechanism (2) and a base (3). The target body (1) is placed on the base (3), and the gas input mechanism (2) is arranged below the base (3). A circular positioning groove (11), a circular air hole (12) and a cavity (13) are provided on the target body (1). The circular positioning groove (11) is arranged at the center of the top of the target body (1), the cavity (13) is arranged inside the target body (1), and the circular air hole (12) is arranged at the circumferential position outside the circular positioning groove (11).

2. The structure of a matrix-assisted spark discharge heated ionization sample target according to claim 1, characterized in that, The gas input mechanism (2) includes a sealing component (21), a first screw (22), a second screw (23) and an air delivery pipe (24). The first screw (22) and the second screw (23) connected to the target body (1) are respectively arranged on the left and right sides of the sealing component (21), and the air delivery pipe (24) communicated with the cavity (13) is arranged at the bottom of the sealing component (21).

3. The structure of a matrix-assisted spark discharge heated ionization sample target according to claim 1, characterized in that, The circular air holes (12) are evenly distributed on the circumferential outside of the circular positioning groove (11).

4. The structure of a matrix-assisted spark discharge heating and ionizing sample target according to claim 1, characterized in that, The upper surface of the target body (1) is a spherical curved surface.

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