Liquid storage device

Abstract

The utility model provides a liquid storage device. The liquid storage device comprises a liquid storage tank and a temperature control tank for supporting the liquid storage tank and controlling the temperature of the liquid storage tank, the interior of the liquid storage tank is a space for storing liquid, a liquid storage hole is formed in the bottom of the liquid storage tank, the liquid storage hole is communicated with the interior of the liquid storage tank, the liquid storage hole is also a space for storing liquid, and the cross sectional area of the liquid storage hole is smaller than that of the liquid storage tank; and the liquid storage hole is arranged corresponding to a suction head for sucking liquid. The liquid storage tank and the temperature control tank are nested, and the liquid storage hole is formed below or at the bottom of the liquid storage tank, so that a large amount of reagent can be stored, the suction head can fully suck liquid, and waste caused by the fact that the large amount of reagent cannot be sucked by the suction head of the automatic pipetting workstation is avoided; and the storage environment and the transfer stability of the liquid can be guaranteed, and the storage and transfer efficiency and quality of the liquid are improved.

Description

Technical Field

[0001] The utility model relates to the technical field of sample detection, and particularly relates to a liquid storage device. Background Art

[0002] In large-scale sample detection or production processes, in order to save time and improve efficiency, an automated pipetting workstation is used to pipette reagents or other liquids. Among them, the corresponding liquid storage device mostly has a smooth bottom. To ensure the smooth liquid extraction of the automated pipetting workstation, the liquid level needs to be raised to a certain position, so a large amount of reagent needs to be added to cover the entire bottom of the liquid storage device. At the same time, since the reagent at the bottom of the liquid storage device cannot be aspirated, a large amount of reagent will be wasted. The prior art improves the liquid level by reducing the cross-sectional area of the liquid storage device, but this solution will bring the technical problem of insufficient storage capacity. On the other hand, when it is necessary to aspirate the reagent at the bottom of the liquid storage device, the pipette tip of the automated pipetting workstation may directly contact the bottom and be blocked, resulting in liquid aspiration blockage. In addition, traditional liquid storage devices have the risk of (biological) reagent degradation and cannot maintain a low temperature environment of 4-8°C, affecting the stability of the reagent. Summary of the Utility Model

[0003] This application is made under the sponsorship of the Hunan Provincial Natural Science Foundation Project (Project No. 2024JJ9165).

[0004] The purpose of the utility model is to provide a liquid storage device that can avoid the waste caused by reagents or other liquids spreading on the bottom of the liquid storage device and being unable to be aspirated, and can also avoid insufficient liquid storage capacity in view of the deficiencies in the above background art.

[0005] To achieve the above purpose, the utility model provides a liquid storage device, including a liquid storage tank and a support part for supporting the liquid storage tank;

[0006] The inside of the liquid storage tank is a space for storing liquid. A liquid storage hole is provided at the bottom of the liquid storage tank. The liquid storage hole is communicated with the inside of the liquid storage tank. The liquid storage hole is also a space for storing liquid. The cross-sectional area of the liquid storage hole is smaller than that of the liquid storage tank;

[0007] The liquid storage hole is correspondingly arranged with a pipette tip for aspirating liquid.

[0008] The liquid storage hole is set as a tapered hole with a gradually decreasing aperture from top to bottom.

[0009] Furthermore, the support part includes a temperature control tank. The liquid storage tank is placed in the temperature control tank, and a temperature regulating substance is contained in the temperature control tank to keep the liquid in the liquid storage tank warm.

[0010] Further, the length and width dimensions of the temperature control tank form a clearance fit with the length and width dimensions of the liquid storage tank.

[0011] Further, a support step is also provided inside the temperature control tank, and the support step is used to support the liquid storage tank so that the liquid storage tank and the liquid storage hole are suspended relative to the bottom surface of the temperature control tank.

[0012] Further, a sealing cover is also provided on the top of the liquid storage tank, and the sealing cover is detachably connected to the liquid storage tank.

[0013] Further, a connection structure is also provided between the sealing cover and the liquid storage tank. The connection structure includes a connection seat and a connection buckle. A clamping groove is provided on the connection seat, and a clamping block corresponding to the clamping groove is provided on the connection buckle. The clamping block is detachably connected to the clamping groove.

[0014] Further, a connection structure is also provided between the liquid storage tank and the temperature control tank. The connection structure includes a connection seat and a connection buckle. A clamping groove is provided on the connection seat, and a clamping block corresponding to the clamping groove is provided on the connection buckle. The clamping block is detachably connected to the clamping groove.

[0015] Further, the clamping groove is made of a ferromagnetic material, and the clamping block is made of a magnet.

[0016] Further, the material of the liquid storage tank is translucent polypropylene, and an anti-ultraviolet coating is also provided on the outer surface of the liquid storage tank.

[0017] The above solution of the present utility model has the following beneficial effects:

[0018] The liquid storage device provided by the present utility model, through the nested setting of the liquid storage tank and the temperature control tank, and the liquid storage hole at the bottom or below the liquid storage tank, can not only store a large amount of reagents, but also ensure sufficient liquid suction of the pipette tip, avoid waste of a large amount of reagents that cannot be sucked by the pipette tip of the automated liquid transfer workstation, and can also ensure the stability of the liquid storage environment and transfer, improving the efficiency and quality of liquid storage and transfer;

[0019] The liquid storage device provided by the present utility model, through the setting of the sealing cover and the sealing ring, can ensure the sealing of the reagent, avoid leakage of the reagent during the transfer of the device and slow evaporation during storage;

[0020] The liquid storage device provided by the present utility model, with the translucent polypropylene of the liquid storage tank and the external anti-ultraviolet coating, on the one hand, can observe the situation of the pipette tip inserted into the liquid, and on the other hand, can prevent ultraviolet rays, which is beneficial to the stability of the reagent;

[0021] Other beneficial effects of the present utility model will be described in detail in the subsequent specific implementation part. Brief Description of the Drawings

[0022] Figure 1 It is a schematic assembly diagram of the overall structure of the present utility model;

[0023] Figure 2 It is a schematic disassembly diagram of the overall structure of the present utility model;

[0024] Figure 3 It is a schematic diagram of the liquid storage tank and liquid storage holes of the present utility model;

[0025] Figure 4 It is a schematic diagram of the liquid storage tank and liquid storage holes of another embodiment of the present utility model;

[0026] Figure 5 It is a schematic diagram of the sealing cover of the present utility model.

[0027]

Description of the Reference Numerals

[0028] 1 - Liquid storage tank; 2 - Liquid storage holes; 3 - Temperature control tank; 4 - Support step; 5 - Sealing cover; 6 - Sealing ring; 7 - Connection seat; 8 - Connection buckle. Detailed Embodiment

[0029] To make the technical problems, technical solutions and advantages to be solved by the present utility model clearer, the following will be described in detail with reference to the drawings and specific embodiments. Obviously, the described embodiments are part of the embodiments of the present utility model, rather than all of the embodiments. All other embodiments obtained by those of ordinary skill in the art based on the embodiments of the present utility model without creative efforts shall fall within the protection scope of the present utility model. In addition, the technical features involved in different embodiments of the present utility model described below can be combined with each other as long as they do not conflict with each other.

[0030] In the description of the present utility model, it should be noted that the orientation or positional relationship indicated by the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", etc. is based on the orientation or positional relationship shown in the drawings, and is only for the convenience of describing the present utility model and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of the present utility model. In addition, the terms "first", "second", "third" are only used for descriptive purposes and cannot be construed as indicating or implying relative importance.

[0031] In the description of the present utility model, it should be noted that unless otherwise clearly specified and defined, the terms "installation", "connection", and "coupling" should be understood in a broad sense. For example, it can be a locking connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be directly connected or indirectly connected through an intermediate medium, and it can be the communication inside two components. For those of ordinary skill in the art, the specific meanings of the above terms in the present utility model can be understood according to specific circumstances.

[0032] As Figure 1 , Figure 2 shown, an embodiment of the present utility model provides a liquid storage device, including a liquid storage tank 1 and a support portion for supporting the liquid storage tank 1. In one implementation, the liquid storage tank 1 is connected with a convex portion protruding outward (downward) relative to the bottom surface of the liquid storage tank 1, and a liquid storage hole 2 is also provided inside the convex portion. The liquid storage hole 2 is communicated with the inside of the liquid storage tank 1 (or regarded as an integral liquid storage space), as Figure 3 shown. Therefore, when filling the reagent into the liquid storage tank 1, under the action of gravity, the reagent will first fill the liquid storage hole 2, and then spread flat to the bottom of the liquid storage tank 1, and the liquid level gradually rises until the reagent is filled with an appropriate capacity and then stops.

[0033] When the automated pipetting workstation sucks the liquid from the liquid storage tank 1 through the pipette tip, the pipette tip can move to the height position where the bottom surface of the liquid storage tank 1 is located and align with each liquid storage hole 2. Of course, it can further extend downward into the inside of the liquid storage hole 2. At this time, the pipette tip is not blocked by the bottom surface of the liquid storage tank 1, and it can still smoothly perform the liquid suction process. Finally, the reagent in the device can be fully sucked and transferred, and only a small amount of reagent will remain in the liquid storage hole 2.

[0034] Since the cross-sectional area of the liquid storage hole 2 is much smaller than the cross-sectional area of the liquid storage tank 1, the liquid storage device provided in this embodiment can not only store a large amount of reagent through the liquid storage tank 1, but also ensure the full liquid suction of the pipette tip through the setting of the liquid storage hole 2, avoiding waste caused by a large amount of reagent that cannot be sucked by the pipette tip of the automated pipetting workstation.

[0035] Of course, in another implementation of this embodiment, the convex portion can also be replaced with a concave portion (upward), as Figure 4 shown, to form the liquid storage hole 2 at the bottom of the liquid storage tank 1, and the same effect can be achieved. This setting method can improve the structural compactness of the liquid storage tank 1.

[0036] It should be noted that the liquid storage device provided in this embodiment can be used to store biological reagents. As a preferred implementation, the number of liquid storage holes 2 in this embodiment is 96, and the layout is consistent with that of a 96-well plate, so that a 96-channel pipetting workstation can directly correspond to the 96 liquid storage holes 2 through a matching pipette tip and aspirate the reagent, and then transfer it into the 96-well plate, significantly improving the reagent transfer efficiency.

[0037] Of course, in other embodiments, the liquid storage device can also store nucleic acid detection reagents, or other reagents, or other liquids (such as chemical catalysts, cleaning solutions), etc. Those skilled in the relevant fields can flexibly select different specifications according to actual needs.

[0038] As a preferred implementation, the protruding part in this embodiment is set to be conical. Correspondingly, the liquid storage hole 2 is also set to be a conical hole with a gradually decreasing aperture from top to bottom, so as to further reduce the residual amount of liquid at the bottom of the liquid storage hole 2.

[0039] In this embodiment, the support part can stably support the liquid storage tank 1 to prevent the reagents or other liquids stored in the liquid storage tank 1 from shaking, pouring, etc. At the same time, for some reagents, they may need to be stored at a low temperature and still need to maintain a low temperature when transferred with the device. Based on this, the support part in this embodiment is also set to be able to maintain the low temperature state inside the liquid storage tank 1. Specifically, the support part is a temperature control tank 3, and the length and width dimensions of the temperature control tank 3 are larger than those of the liquid storage tank 1, so that the liquid storage tank 1 can be placed inside the temperature control tank 3. Ice cubes, biological ice packs or ice-water mixtures are installed in the temperature control tank 3, so that the liquid in the liquid storage tank 1 is in a low temperature state, ensuring the stability of the reagent. Of course, heating substances can also be placed in the temperature control tank 3, so that the liquid in the liquid storage tank 1 is in a high temperature state.

[0040] It should be noted that to ensure that the liquid storage tank 1 is placed stably in the temperature control tank 3, the length and width dimensions of the temperature control tank 3 are preferably only slightly larger than those of the liquid storage tank 1 to form a clearance fit. At the same time, to ensure that the liquid storage tank 1 is placed reasonably in the temperature control tank 3 filled with ice cubes or biological ice packs, a support step 4 is further provided inside the temperature control tank 3 in this embodiment. Through the support step 4, the minimum size inside the temperature control tank 3 is smaller than that of the liquid storage tank 1, so that when the liquid storage tank 1 is supported, the liquid storage tank 1 and the liquid storage hole 2 are suspended relative to the bottom surface of the temperature control tank 3 and will not be obstructed by ice cubes or biological ice packs.

[0041] As described above, the temperature control tank 3 and the liquid storage tank 1 adopt a detachable connection method. When it is necessary to replace or clean the ice cubes in the temperature control tank 3, or when it is necessary to clean the liquid storage tank 2, only need to disassemble and separate the liquid storage tank 1 and the temperature control tank 3. When installing, align the liquid storage tank 1 with the temperature control tank 3 and insert it into the temperature control tank 3 until the liquid storage tank 1 is limited by the support step 4.

[0042] In this embodiment, a sealing cover 5 is further provided at the top of the liquid storage tank 1. The sealing cover 5 is used to seal the top of the liquid storage tank 1 to maintain a sealed environment for the reagent in the liquid storage tank 1, prevent the reagent from overflowing during the transfer of the entire device, and reduce the evaporation amount during reagent storage. As a preferred implementation, a sealing ring 6 is further provided at the edge position of the sealing cover 5 in this embodiment. As shown in Figure 5 the figure, a sealing groove corresponding to the sealing ring 6 is provided at the top of the liquid storage tank 1. When the sealing cover 5 is closed, the sealing ring 6 can be snapped into the sealing groove to further ensure the sealing effect.

[0043] To further ensure the connection stability between the sealing cover 5 and the liquid storage tank 1 during device transfer, and the connection stability between the liquid storage tank 1 and the temperature control tank 3, a connection structure is further provided between the sealing cover 5 and the liquid storage tank 1, and between the liquid storage tank 1 and the temperature control tank 3 in this embodiment, so that the sealing cover 5 can be stably connected to the liquid storage tank 1 and detached from the liquid storage tank 1, and the liquid storage tank 1 can be stably connected to the temperature control tank 3 and detached from the temperature control tank 3.

[0044] In a specific implementation of this embodiment, the connection structure includes a connection seat 7 and a connection buckle 8. A clamping groove is provided on the connection seat 7 and is made of ferromagnetic material. A clamping block corresponding to the clamping groove is provided on the connection buckle 8 and is made of magnet. Therefore, during connection, only the clamping block on the connection buckle 8 needs to be inserted into the clamping groove on the connection seat 7 and fixed by magnetic attraction. Among them, the connection seat 7 can be provided on the sealing cover 5 and the liquid storage tank 1, and the corresponding connection buckle 8 can be provided on the liquid storage tank 1 and the temperature control tank 3, or vice versa. In other specific implementations, the clamping groove and the clamping buckle can also be fixed by elastic buckling, Velcro, etc., and those skilled in the art can flexibly select according to costs, installation convenience, etc.

[0045] As a preferred implementation of this embodiment, the material of the liquid storage tank 1 is translucent polypropylene, and an anti-ultraviolet coating is further provided on the outer surface. On the one hand, it can observe the situation of the pipette tip inserted into the liquid, and on the other hand, it can prevent ultraviolet rays, which is beneficial to the stability of the reagent.

[0046] In summary, the liquid storage device provided in this embodiment, through the nested setting of the liquid storage tank 1 and the temperature control tank 3, and the liquid storage hole 2 below the liquid storage tank 3, can not only store a large amount of reagent, but also ensure sufficient liquid suction of the pipette tip, avoid waste of a large amount of reagent that cannot be sucked by the pipette tip of the automated pipetting workstation, and can also ensure the low-temperature environment of the liquid and the stability of transfer, improving the efficiency and quality of liquid storage and transfer.

[0047] The technical features of the above embodiments can be combined arbitrarily. For the sake of concise description, not all possible combinations of the technical features in the above embodiments are described. However, as long as there is no contradiction in the combination of these technical features, it should be considered as the scope recorded in this specification.

[0048] The above embodiments only express several implementation manners of the present application, and the description is relatively specific and detailed, but it should not be understood as a limitation to the scope of the application. It should be noted that for those of ordinary skill in the art, without departing from the concept of the present application, several deformations and improvements can still be made, and these all belong to the protection scope of the present application. Therefore, the protection scope of the present application should be subject to the appended claims.

Claims

1. A liquid storage device, characterized in that, It includes a liquid storage tank (1) and a support part for supporting the liquid storage tank (1); The interior of the liquid storage tank (1) is a space for storing liquid. A liquid storage hole (2) is provided at the bottom of the liquid storage tank (1). The liquid storage hole (2) is communicated with the interior of the liquid storage tank (1). The liquid storage hole (2) is also a space for storing liquid. The cross-sectional area of the liquid storage hole (2) is smaller than the cross-sectional area of the liquid storage tank (1); the liquid storage hole (2) is correspondingly arranged with a pipette tip for sucking liquid.

2. The liquid storage device according to claim 1, wherein The liquid storage hole (2) is arranged as a tapered hole and the aperture gradually decreases from top to bottom.

3. The liquid storage device according to claim 1, wherein, The support part includes a temperature control tank (3). The liquid storage tank (1) is placed in the temperature control tank (3). A temperature regulating substance is contained in the temperature control tank (3) to keep the liquid in the liquid storage tank (1) warm.

4. The liquid storage device according to claim 3, wherein, The length and width dimensions of the temperature control tank (3) form a clearance fit with the length and width dimensions of the liquid storage tank (1).

5. The liquid storage device according to claim 3, characterized in that, A support step (4) is further provided inside the temperature control tank (3). The support step (4) is used to support the liquid storage tank (1) so that the liquid storage tank (1) and the liquid storage hole (2) are suspended relative to the bottom surface of the temperature control tank (3).

6. The liquid storage device according to claim 1, characterized in that, A sealing cover (5) is further provided at the top of the liquid storage tank (1). The sealing cover (5) is detachably connected to the liquid storage tank (1).

7. The liquid storage device according to claim 6, wherein, A connection structure is further provided between the sealing cover (5) and the liquid storage tank (1). The connection structure includes a connection seat (7) and a connection buckle (8). A clamping groove is provided on the connection seat (7). A clamping block corresponding to the clamping groove is provided on the connection buckle (8). The clamping block is detachably connected to the clamping groove.

8. The liquid storage device according to claim 3, characterized in that, A connection structure is further provided between the liquid storage tank (1) and the temperature control tank (3). The connection structure includes a connection seat (7) and a connection buckle (8). A clamping groove is provided on the connection seat (7). A clamping block corresponding to the clamping groove is provided on the connection buckle (8). The clamping block is detachably connected to the clamping groove.

9. The liquid storage device according to claim 7 or 8, characterized in that, The clamping groove is made of a ferromagnetic material and the clamping block is made of a magnet.

10. The liquid storage device according to claim 1, characterized in that, The material of the liquid storage tank (1) is translucent polypropylene. An anti-ultraviolet coating is further provided on the outer surface of the liquid storage tank (1).

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