Biopharmaceutical fermentation tank

Abstract

The utility model relates to the technical field of biopharmacy, and particularly discloses a biopharmacy fermentation tank which comprises a tank body, a stirring mechanism arranged in the tank body and used for stirring fermentation liquor, and a cleaning mechanism arranged in the tank body and used for cleaning the fermentation liquor on the inner wall of the tank body. The cleaning mechanism comprises a scraping ring, a driving part and a cleaning part, the scraping ring is slidably connected into the tank body, a guide groove is formed in the upper end face of the scraping ring, the driving part is arranged at the upper end of the scraping ring, and the cleaning part is arranged in the scraping ring. Through the synergistic effect of the scraping ring, the driving component and the cleaning component, the scraping ring is driven by the driving component to move downwards, in the process, water flow sprayed by the cleaning component can effectively wash the interior of the tank body above and below the scraping ring, residues on the inner wall of the tank body are effectively removed, and the service life of the tank body is prolonged. The problem that fermentation liquor on the inner wall of the fermentation tank is difficult to clean is solved.

Description

Technical Field

[0001] The utility model belongs to the technical field of biopharmaceuticals, and particularly relates to a biopharmaceutical fermenter. Background Art

[0002] A fermenter refers to a device used for microbial fermentation in industry. Its main body is generally a main cylinder made of stainless steel plate. In design and processing, attention should be paid to the strict and reasonable structure, and it can be adjusted to facilitate cleaning, reduce pollution, be suitable for the production of various products, and reduce energy consumption.

[0003] However, after fermentation in the existing fermenter, the fermentation broth is likely to adhere to the inner wall of the fermenter, which not only increases the difficulty of cleaning, but may also have an adverse impact on the subsequent microbial fermentation process. For this reason, we propose a biopharmaceutical fermenter to solve the above problems. Summary of the Utility Model

[0004] The purpose of the utility model is to provide a biopharmaceutical fermenter to solve the problem that the fermentation broth on the inner wall of the existing fermenter is difficult to clean.

[0005] To achieve the above purpose, the utility model provides the following technical solutions:

[0006] A biopharmaceutical fermenter includes a tank body. A stirring mechanism is arranged inside the tank body, and the stirring mechanism is used for stirring the fermentation broth. A cleaning mechanism is arranged inside the tank body, and the cleaning mechanism is used for cleaning the fermentation broth on the inner wall of the tank.

[0007] Preferably: The cleaning mechanism includes a scraping ring, a driving component, and a cleaning component. The scraping ring is slidably connected inside the tank body. A guide groove is opened on the upper end surface of the scraping ring. A driving component is arranged at the upper end of the scraping ring, and a cleaning component is arranged inside the scraping ring.

[0008] Preferably: The driving component includes a support rod and a second motor. The upper end of the scraping ring is equidistantly and fixedly connected with support rods. The upper ends of the support rods penetrate through the upper end of the tank body and are slidably connected therewith. A connecting frame is fixedly connected between the upper ends of multiple groups of support rods. The second motor is fixedly connected to the upper end of the tank body. The output shaft end of the second motor is fixedly connected with a threaded rod. The upper end of the threaded rod penetrates through the connecting frame and is threadedly connected therewith.

[0009] Preferably: The cleaning component includes an annular pipe and a connecting pipe. Fixed blocks are equidistantly and fixedly connected to the inner wall of the scraping ring. Annular pipes are fixedly connected to both the upper and lower ends of the fixed blocks. Spray openings are opened on both the inner and outer walls of the annular pipe.

[0010] Preferably, connecting pipes are fixedly and equidistantly connected between the two groups of the annular pipes. The upper ends of the connecting pipes penetrate through the tank body and are slidably connected thereto. A tee pipe is fixedly connected between the upper ends of the two groups of connecting pipes. A fixing block is fixedly connected to the side wall of the connecting rod located above the tank body, and the fixing block is fixedly connected to the side wall of the connecting frame.

[0011] Preferably, the stirring mechanism includes a rotating shaft and stirring rods. The rotating shaft is rotatably connected to the side wall of the tank body. Stirring rods are fixedly connected to the side wall of the rotating shaft at equal intervals. Extension rods are rotatably connected to both ends of the stirring rods. Both ends of the stirring rods are far away from the inner wall of the scraping ring. A first motor is fixedly connected to the upper end of the tank body, and the output shaft end of the first motor is fixedly connected to the upper end of the rotating shaft.

[0012] Preferably, a connecting rod is fixedly connected to the side wall of the rotating shaft, and a scraping plate is fixedly connected to the side of the connecting rod away from the rotating shaft. The scraping plate abuts against the inner wall of the tank body.

[0013] Compared with the prior art, the beneficial effects of the present utility model are as follows:

[0014] 1. Through the synergistic effect of the scraping ring, the driving component and the cleaning component, the present utility model realizes that the scraping ring moves downward driven by the driving component. During this process, the water flow sprayed by the cleaning component can effectively wash the inside of the tank body above and below the scraping ring, effectively removing the residues on the inner wall of the tank body.

[0015] 2. Since both ends of the stirring rods are far away from the inner wall of the scraping ring, the present utility model ensures that the cleaning mechanism can smoothly move downward along the inner wall of the tank body. In addition, extension rods are installed at both ends of the stirring rods. When the rotating shaft rotates, with the help of the centrifugal force, the extension rods will rotate and adjust to a position parallel to the horizontal plane, which expands the stirring range and thus improves the stirring efficiency.

[0016] 3. The present utility model installs a connecting rod and a scraping plate structure inside the lower end of the tank body, so that when the rotating shaft rotates, the side wall of the lower end of the tank body can be effectively cleaned. This design helps to prevent the deposits generated during the fermentation process from caking and adhering to the tank wall, keeping the inside of the tank body clean. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] Figure 1 is the overall front view structural schematic diagram of the present utility model;

[0018] Figure 2 is the sectional structural schematic diagram of the tank body of the present utility model;

[0019] Figure 3 is the overall structural schematic diagram of the cleaning component of the present utility model;

[0020] Figure 4 is the overall top view plane structural schematic diagram of the present utility model.

[0021] In the figure: 1, tank body; 2, stirring mechanism; 21, rotating shaft; 22, stirring rod; 23, extension rod; 24, connecting rod; 25, scraper; 26, first motor; 3, cleaning mechanism; 31, scraping ring; 311, guide groove; 32, driving component; 321, support rod; 322, connecting frame; 323, second motor; 324, threaded rod; 325, fixed block; 33, cleaning component; 331, connecting block; 332, annular pipe; 333, water spraying port; 334, connecting pipe; 335, tee pipe. Specific embodiments

[0022] Next, the technical solutions in the embodiments of the present invention will be clearly and completely described in conjunction with the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without making creative efforts shall fall within the protection scope of the present invention.

[0023] Referring to Figure 1 - Figure 2 As shown, the present invention provides a biopharmaceutical fermentation tank, including a tank body 1. A stirring mechanism 2 is arranged inside the tank body 1, and the stirring mechanism 2 is used for stirring the fermentation broth. A cleaning mechanism 3 is arranged inside the tank body 1, and the cleaning mechanism 3 is used for cleaning the fermentation broth on the inner wall of the tank body 1; on the one hand, the arranged stirring mechanism 2 stirs the fermentation broth, and on the other hand, it can prevent the precipitates generated during the fermentation process from caking and adhering to the tank wall; through the cleaning mechanism 3, the inside of the tank body 1 is further cleaned, thereby solving the problem that the fermentation broth on the inner wall of the fermentation tank is difficult to clean.

[0024] In a further embodiment, referring to Figure 2 - Figure 3 , the cleaning mechanism 3 includes a scraping ring 31, a driving component 32 and a cleaning component 33. A scraping ring 31 is slidably connected inside the tank body 1. A guide groove 311 is opened on the upper end surface of the scraping ring 31. A driving component 32 is arranged above the scraping ring 31, and a cleaning component 33 is arranged inside the scraping ring 31.

[0025] In this embodiment, the scraping ring 31 moves downward under the drive of the driving component 32. During this process, the water flow sprayed by the cleaning component 33 can effectively wash the inside of the tank body 1 above and below the scraping ring 31, and effectively remove the residues on the inner wall of the tank body 1.

[0026] In a further embodiment, referring to Figure 2, the driving component 32 includes a support rod 321 and a second motor 323. The upper end of the scraping ring 31 is fixedly connected with the support rod 321 at equal intervals. The upper end of the support rod 321 penetrates through the upper end of the tank body 1 and is slidably connected thereto. A connecting frame 322 is fixedly connected between the upper ends of multiple groups of support rods 321. A second motor 323 is fixedly connected to the upper end of the tank body 1. A threaded rod 324 is fixedly connected to the output shaft end of the second motor 323. The upper end of the threaded rod 324 penetrates through the connecting frame 322 and is threadedly connected thereto.

[0027] In this embodiment, by starting the second motor 323 to drive the threaded rod 324 to rotate, the rotation of the threaded rod 324 drives the connecting frame 322 to move downward. The downward movement of the connecting frame 322 drives the support rod 321 to move downward. The downward movement of the support rod 321 drives the scraping ring 31 to slide downward inside the tank body 1, so as to initially clean the inner wall of the tank body 1 through the sliding scraping ring 31.

[0028] In a further embodiment, referring to Figure 2 - Figure 4 , the cleaning component 33 includes an annular pipe 332 and a connecting pipe 334. Fixed blocks 325 are fixedly connected to the inner wall of the scraping ring 31 at equal intervals. Annular pipes 332 are fixedly connected to both the upper and lower ends of the fixed block 325. Water spraying openings 333 are formed on both the inner and outer walls of the annular pipe 332. Connecting pipes 334 are fixedly connected between the two groups of annular pipes 332 at equal intervals. The upper end of the connecting pipe 334 penetrates through the tank body 1 and is slidably connected thereto. A tee pipe 335 is fixedly connected between the upper ends of the two groups of connecting pipes 334. A fixed block 325 is fixedly connected to the side wall of the connecting rod located above the tank body 1. The fixed block 325 is fixedly connected to the side wall of the connecting frame 322.

[0029] In this embodiment, by connecting a high-pressure water pipe to the tee pipe 335, the high-pressure flowing water reaches the annular pipe 332 through the connecting pipe 334 and sprays out from the water spraying openings 333. Since the water spraying openings 333 are formed on both the inner and outer walls of the annular pipe 332, it is possible to wash the inner wall of the tank body 1 and clean the stirring rod 22 at the same time.

[0030] In a further embodiment, referring to Figure 2 , the stirring mechanism 2 includes a rotating shaft 21 and stirring rods 22. The rotating shaft 21 is rotatably connected to the side wall of the tank body 1. Stirring rods 22 are fixedly connected to the side wall of the rotating shaft 21 at equal intervals. Extension rods 23 are rotatably connected to both ends of the stirring rod 22. Both ends of the stirring rod 22 are far away from the inner wall of the scraping ring 31. A first motor 26 is fixedly connected to the upper end of the tank body 1. The output shaft end of the first motor 26 is fixedly connected to the upper end of the rotating shaft 21. A connecting rod 24 is fixedly connected to the side wall of the rotating shaft 21. A scraping plate 25 is fixedly connected to the side of the connecting rod 24 away from the rotating shaft 21. The scraping plate 25 is in contact with the inner wall of the tank body 1.

[0031] In this embodiment, starting the first motor 26 drives the rotation of the rotating shaft 21. While the rotating shaft 21 rotates, it drives the rotation of the stirring rod 22. When the rotating shaft 21 rotates, the extension rod 23 will rotate and adjust to a position parallel to the horizontal plane by means of centrifugal force. This design expands the stirring range and thus improves the stirring efficiency. While the rotating shaft 21 rotates, it drives the rotation of the connecting rod 24, and the rotation of the connecting rod 24 drives the movement of the scraper 25, so as to effectively clean the side wall at the lower end of the tank body 1. This design helps to prevent the sediment generated during the fermentation process from caking and adhering to the tank wall, and keeps the inside of the tank body 1 clean.

[0032] Although the embodiments of the present invention have been shown and described, those of ordinary skill in the art can understand that various changes, modifications, substitutions and variations can be made to these embodiments without departing from the principle and spirit of the present invention. The scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A biopharmaceutical fermenter, comprising a tank body (1), characterized in that, Inside the tank body (1), a stirring mechanism (2) is provided, and the stirring mechanism (2) is used for stirring the fermentation broth. Inside the tank body (1), a cleaning mechanism (3) is provided, and the cleaning mechanism (3) is used for cleaning the fermentation broth on the inner wall of the tank body (1).

2. The biopharmaceutical fermenter according to claim 1, wherein: The cleaning mechanism (3) includes a scraping ring (31), a driving component (32), and a cleaning component (33). A scraping ring (31) is slidably connected inside the tank body (1). A guide groove (311) is formed on the upper end surface of the scraping ring (31). A driving component (32) is arranged above the scraping ring (31), and a cleaning component (33) is arranged inside the scraping ring (31).

3. A biopharmaceutical fermenter according to claim 2, characterized in that: The driving component (32) includes a support rod (321) and a second motor (323). Support rods (321) are fixedly connected to the upper end of the scraping ring (31) at equal intervals. The upper ends of the support rods (321) penetrate through the upper end of the tank body (1) and are slidably connected thereto. A connecting frame (322) is fixedly connected between the upper ends of the multiple support rods (321). A second motor (323) is fixedly connected to the upper end of the tank body (1). A threaded rod (324) is fixedly connected to the output shaft end of the second motor (323). The upper end of the threaded rod (324) penetrates through the connecting frame (322) and is threadedly connected thereto.

4. A biopharmaceutical fermenter according to claim 2, characterized in that: The cleaning component (33) includes an annular pipe (332) and a connecting pipe (334). Fixed blocks (325) are fixedly connected to the inner wall of the scraping ring (31) at equal intervals. Annular pipes (332) are fixedly connected to both the upper and lower ends of the fixed blocks (325). Water spraying openings (333) are formed on both the inner and outer walls of the annular pipe (332).

5. A biopharmaceutical fermenter according to claim 4, characterized in that: Connecting pipes (334) are fixedly and equally spaced between the two annular pipes (332). The upper ends of the connecting pipes (334) penetrate through the tank body (1) and are slidably connected thereto. A tee pipe (335) is fixedly connected between the upper ends of the two connecting pipes (334). A fixed block (325) is fixedly connected to the side wall of the connecting rod located above the tank body (1). The fixed block (325) is fixedly connected to the side wall of the connecting frame (322).

6. A biopharmaceutical fermenter according to claim 1, characterized in that: The stirring mechanism (2) includes a rotating shaft (21) and stirring rods (22). The rotating shaft (21) is rotatably connected to the side wall of the tank body (1). Stirring rods (22) are fixedly connected to the side wall of the rotating shaft (21) at equal intervals. Extension rods (23) are rotatably connected to both ends of the stirring rods (22). Both ends of the stirring rods (22) are away from the inner wall of the scraping ring (31). A first motor (26) is fixedly connected to the upper end of the tank body (1). The output shaft end of the first motor (26) is fixedly connected to the upper end of the rotating shaft (21).

7. A biopharmaceutical fermenter according to claim 6, characterized in that: A connecting rod (24) is fixedly connected to the side wall of the rotating shaft (21). A scraping plate (25) is fixedly connected to the side of the connecting rod (24) away from the rotating shaft (21). The scraping plate (25) abuts against the inner wall of the tank body (1).

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