Uniform mixing device for pharmacokinetics experiment sample

Abstract

The utility model relates to the technical field of pharmacokinetics experiments, and discloses a pharmacokinetics experiment sample mixing device which comprises a bedplate, a stirring tank is fixedly arranged in the middle of the top end of the bedplate, air cylinders are installed at the four corners of the outer end of the stirring tank, the top ends of the four air cylinders are connected with a top cover, a scraping plate is installed at the bottom end of the top cover, and the scraping plate is fixedly connected with the bedplate. The outer side of the scraping plate is attached to the inner wall of the stirring tank. The air cylinders are installed at the four ends of the outer side of the stirring tank, then the top cover is installed at the topmost portions of the four air cylinders, the driving structure is installed at the lower end of the top cover, the air cylinders stretch out upwards so that the stirring structure can be controlled to move upwards, and cleaning of the stirring structure in the later period is facilitated; the outer surface of the scraper is attached to the inner wall of the stirring tank, the scraper can scrape off residual samples on the inner wall of the stirring tank by moving the top cover upwards, and the situation that the samples are accumulated on the inner wall of the stirring pipe and are difficult to clean is avoided.

Description

Technical Field

[0001] The utility model relates to the technical field of pharmacokinetic experiments, in particular to a pharmacokinetic experiment sample mixing device. Background Art

[0002] During drug development, pharmacokinetic samples are used to screen drug candidates, optimize dosage forms, and evaluate drug pharmacokinetic properties, providing important evidence for clinical development. The purpose of pharmacokinetic samples is to gain a deeper understanding of the drug's in vivo disposition, providing scientific evidence and support for drug development, clinical application, and personalized treatment.

[0003] The stirring structure of traditional pharmacokinetic experimental sample mixing devices is mostly fixed in a fixed position, usually fixed inside the stirring tank, which makes it inconvenient to clean the stirring structure later. In addition, after the traditional mixing device mixes the sample, some sample may remain on the inner wall of the stirring tank, making it difficult to clean.

[0004] Therefore, those skilled in the art provide a pharmacokinetic experimental sample mixing device to solve the problems raised in the above background technology. Utility Model Content

[0005] The purpose of the utility model is to solve the shortcomings existing in the prior art, and a pharmacokinetic experimental sample mixing device is proposed. Cylinders are installed at the four ends of the outer side of the stirring tank, and then a top cover is installed at the top of the four cylinders. The driving structure is installed at the lower end of the top cover. The upward extension of the cylinder can control the upward movement of the stirring structure, which is convenient for the later cleaning of the stirring structure. At the same time, a scraper is provided at the bottom end of the top cover. The outer surface of the scraper is in contact with the inner wall of the stirring tank. When the top cover is moved upward, the scraper will scrape off the sample remaining on the inner wall of the stirring tank, avoiding the accumulation of samples on the inner wall of the stirring tube that is difficult to clean.

[0006] To achieve the above objectives, the present invention provides the following technical solutions:

[0007] A pharmacokinetic experimental sample mixing device comprises a platform, a stirring tank is fixedly mounted at the middle of the top of the platform, cylinders are mounted at the four corners of the outer end of the stirring tank, the top ends of the four cylinders are connected to top covers, and a scraper is mounted at the bottom end of the top cover, the outer side of the scraper is in contact with the inner wall of the stirring tank;

[0008] Through the above technical solution, cylinders are installed at the four ends of the outer side of the stirring tank, and then the top cover is installed at the top of the four cylinders, and the driving structure is installed at the lower end of the top cover. The upward extension of the cylinder can control the stirring structure to move upward, which is convenient for the later cleaning of the stirring structure. At the same time, a scraper is provided at the bottom end of the top cover, and the outer surface of the scraper is in contact with the inner wall of the stirring tank. When the scraper moves upward by the top cover, the sample remaining on the inner wall of the stirring tank will be scraped off, thereby avoiding the accumulation of samples on the inner wall of the stirring tube and making it difficult to clean.

[0009] Furthermore, a fixing box is provided at the middle of the top end of the top cover, a driving motor is installed on one side of the fixing box, a driving helical gear is provided inside the fixing box at the output end of the driving motor, a driven helical gear is meshed with the bottom end of the driving helical gear, a rotating shaft is provided in the middle of the driven helical gear, and a plurality of stirring blades are installed at the outer end of the rotating shaft;

[0010] With the above technical solution, the rotation of the rotating shaft can be controlled by the coordinated transmission between the driving motor and the active helical gear and the driven helical gear.

[0011] Furthermore, a discharge pipe is provided at the bottom end of the platform and connected to the stirring tank, and a control valve is provided at the middle end of the discharge pipe;

[0012] According to the above technical solution, a discharge pipe is provided at the bottom end of the table and connected to the stirring tank, and a control valve is provided at the middle end of the discharge pipe to facilitate the control of sample discharge.

[0013] Furthermore, the plurality of stirring blades are designed to be inclined, and a plurality of through holes are opened in the middle of the plurality of stirring blades;

[0014] Through the above technical solution, by designing multiple stirring blades to be inclined and opening multiple through holes in the middle of multiple stirring blades, the impact force between the stirring blades and the sample during the stirring process can be reduced, avoiding excessive impact force between the stirring blades and the sample, which may cause damage to the stirring blades and greatly improve the service life of the stirring blades.

[0015] Furthermore, support legs are fixedly provided at the four corners of the bottom end of the platform;

[0016] Through the above technical solution, the support legs are fixedly provided at the four corners of the bottom end of the table, thereby facilitating the support of the entire device.

[0017] Furthermore, a control panel is provided on the top of the table, which is electrically connected to the four cylinders and the drive motor 10;

[0018] Through the above technical solution, a control panel is provided on the top of the table that is electrically connected to the four cylinders and the drive motor, thereby facilitating control of the entire device.

[0019] Furthermore, a plurality of fixing bolts are provided at the fitting positions of the driving motor and the top cover;

[0020] According to the above technical solution, a plurality of fixing bolts are provided at the fitting positions of the driving motor and the top cover, thereby facilitating the fixing of the driving motor.

[0021] The utility model has the following beneficial effects:

[0022] 1. The utility model proposes a pharmacokinetic experimental sample mixing device, which is achieved by installing cylinders on the four ends of the outer side of the stirring tank, and then the top cover is installed at the top of the four cylinders, and the driving structure is installed at the lower end of the top cover. The upward extension of the cylinder can control the upward movement of the stirring structure, which is convenient for the later cleaning of the stirring structure. At the same time, a scraper is provided at the bottom end of the top cover, and the outer surface of the scraper is in contact with the inner wall of the stirring tank. When the top cover is moved upward, the scraper will scrape off the sample remaining on the inner wall of the stirring tank, thereby avoiding the accumulation of samples on the inner wall of the stirring tube and preventing them from being difficult to clean.

[0023] 2. The utility model proposes a pharmacokinetic experimental sample mixing device, which can control the rotation of the rotating shaft through the coordinated transmission between the driving motor and the active bevel gear and the driven bevel gear, and the stirring blades arranged at the outer end of the rotating shaft are all arranged in an inclined shape and have multiple through holes, so as to reduce the impact force between the stirring blade and the sample during the stirring process, avoid excessive impact force between the stirring blade and the sample, resulting in damage to the stirring blade, and greatly improve the service life of the stirring blade. BRIEF DESCRIPTION OF THE DRAWINGS

[0024] Figure 1 This is an isometric view of a pharmacokinetic experimental sample mixing device proposed by the utility model;

[0025] Figure 2 This is a cross-sectional view of a pharmacokinetic experimental sample mixing device proposed by the present invention;

[0026] Figure 3 This is a top axonometric view of a pharmacokinetic experimental sample mixing device proposed in the present invention;

[0027] Figure 4 This is an axonometric diagram of the stirring structure of a pharmacokinetic experimental sample mixing device proposed in the present invention;

[0028] Figure 5 This is an axonometric diagram of the support structure of a pharmacokinetic experimental sample mixing device proposed in the utility model.

[0029] Legend:

[0030] 1. Table; 2. Support legs; 3. Mixing tank; 4. Cylinder; 5. Top cover; 6. Discharge pipe; 7. Control valve; 8. Control panel; 9. Fixing box; 10. Drive motor; 11. Fixing bolts; 12. Driving bevel gear; 13. Driven bevel gear; 14. Rotating shaft; 15. Mixing blade; 16. Through hole; 17. Scraper. DETAILED DESCRIPTION

[0031] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the embodiments described are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative efforts are within the scope of protection of the present invention.

[0032] Reference Figure 1-5 The utility model provides an embodiment of a pharmacokinetic experimental sample mixing device, comprising a platform 1, a stirring tank 3 is fixedly provided in the middle of the top of the platform 1, and cylinders 4 are installed at the four corners of the outer end of the stirring tank 3. The tops of the four cylinders 4 are connected to a top cover 5, and a scraper 17 is installed at the bottom end of the top cover 5. The outer side of the scraper 17 fits the inner wall of the stirring tank 3. The cylinders 4 are installed at the four ends of the outer side of the stirring tank 3, and then the top cover 5 is installed at the top of the four cylinders 4. The driving structure is installed at the lower end of the top cover 5, and the stirring structure can be controlled to move upward by extending the cylinder 4 upward, which is convenient for cleaning the stirring structure later. At the same time, a scraper 17 is provided at the bottom end of the top cover 5, and the outer surface of the scraper 17 fits the inner wall of the stirring tank 3. When the scraper 17 moves upward by the top cover 5, the sample remaining on the inner wall of the stirring tank 3 is scraped off, avoiding the accumulation of the sample on the inner wall of the stirring tube that is difficult to clean.

[0033] A fixed box 9 is provided in the middle of the top of the top cover 5, and a driving motor 10 is installed on one side of the fixed box 9. A driving bevel gear 12 is provided inside the fixed box 9 at the output end of the driving motor 10, and a driven bevel gear 13 is meshed with the bottom end of the driving bevel gear 12. A rotating shaft 14 is provided in the middle of the driven bevel gear 13, and a plurality of stirring blades 15 are installed at the outer end of the rotating shaft 14. Through the coordinated transmission between the driving motor 10 and the driving bevel gear 12 and the driven bevel gear 13, the rotation of the rotating shaft 14 can be controlled. The bottom end of the table 1 is connected to the stirring tank 3 and a discharge pipe 6 is provided. The middle end of the discharge pipe 6 is provided with a control valve 7. The discharge pipe 6 is provided by connecting the bottom end of the table 1 to the stirring tank 3. The middle end of the discharge pipe 6 is provided with a control valve 7 to facilitate the discharge of the sample. The multiple stirring blades 15 are designed to be inclined, and the middle part of the multiple stirring blades 15 is provided with a plurality of through holes 16. It is designed to be inclined, and a plurality of through holes 16 are provided in the middle of the plurality of stirring blades 15 to reduce the impact force between the stirring blades 15 and the sample during stirring, avoid excessive impact force between the stirring blades 15 and the sample, which causes damage to the stirring blades 15, and greatly improves the service life of the stirring blades 15. Support legs 2 are fixedly provided at the four corners of the bottom end of the table 1. By fixing the support legs 2 at the four corners of the bottom end of the table 1, it is convenient to support the entire device. A control panel 8 is provided at the top of the table 1, which is electrically connected to the four cylinders 4 and the drive motor 10. A control panel 8 is provided at the top of the table 1, which is electrically connected to the four cylinders 4 and the drive motor 10, so as to facilitate control of the entire device. A plurality of fixing bolts 11 are provided at the fitting position of the drive motor 10 and the top cover 5. By providing a plurality of fixing bolts 11 at the fitting position of the drive motor 10 and the top cover 5, it is convenient to fix the drive motor 10.

[0034] Working principle: Cylinders 4 are installed at the four ends of the outer side of the stirring tank 3, and then the top cover 5 is installed at the top of the four cylinders 4, and the driving structure is installed at the lower end of the top cover 5. The upward extension of the cylinder 4 can control the stirring structure to move upward, which is convenient for cleaning the stirring structure in the later stage. At the same time, a scraper 17 is provided at the bottom end of the top cover 5. The outer surface of the scraper 17 is in contact with the inner wall of the stirring tank 3. When the top cover 5 moves upward, the scraper 17 will scrape the sample remaining on the inner wall of the stirring tank 3 to avoid the sample accumulating on the inner wall of the stirring tube and being difficult to clean. The driving motor 10 and the active bevel gear 12 and the driven bevel gear 13 are matched to each other to control the rotation of the rotating shaft 14. The stirring blades 15 arranged at the outer end of the rotating shaft 14 are all arranged to be inclined and have multiple through holes 16 to reduce the impact force between the stirring blade 15 and the sample during the stirring process, avoid excessive impact between the stirring blade 15 and the sample, resulting in damage to the stirring blade 15, and greatly improve the service life of the stirring blade 15.

[0035] Finally, it should be noted that the above is only a preferred embodiment of the present invention and is not intended to limit the present invention. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art can still modify the technical solutions described in the aforementioned embodiments or make equivalent replacements for some of the technical features therein. Any modifications, equivalent replacements, improvements, etc. made within the spirit and principles of the present invention should be included in the scope of protection of the present invention.

Claims

1. A pharmacokinetic experimental sample mixing device, comprising a platform (1), characterized in that: A stirring tank (3) is fixedly provided at the middle of the top end of the platform (1), cylinders (4) are installed at the four corners of the outer end of the stirring tank (3), the top ends of the four cylinders (4) are connected to top covers (5), and a scraper (17) is installed at the bottom end of the top cover (5), and the outer side of the scraper (17) is in contact with the inner wall of the stirring tank (3).

2. A pharmacokinetic experimental sample mixing device according to claim 1, characterized in that: A fixed box (9) is provided at the middle of the top end of the top cover (5), a driving motor (10) is installed on one side of the fixed box (9), a driving helical gear (12) is provided inside the fixed box (9) at the output end of the driving motor (10), a driven helical gear (13) is meshed with the bottom end of the driving helical gear (12), a rotating shaft (14) is provided in the middle of the driven helical gear (13), and a plurality of stirring blades (15) are installed at the outer end of the rotating shaft (14).

3. The pharmacokinetic experiment sample mixing device according to claim 1, characterized in that: The bottom end of the platform (1) is connected to the stirring tank (3) and is provided with a discharge pipe (6), and the middle end of the discharge pipe (6) is provided with a control valve (7).

4. The pharmacokinetic experiment sample mixing device according to claim 2, characterized in that: The plurality of stirring blades (15) are all designed to be inclined, and a plurality of through holes (16) are provided in the middle of the plurality of stirring blades (15).

5. The pharmacokinetic experiment sample mixing device according to claim 1, characterized in that: Support legs (2) are fixedly provided at the four corners of the bottom end of the platform (1).

6. The pharmacokinetic experiment sample mixing device according to claim 1, characterized in that: A control panel (8) is provided at the top of the platform (1) and is electrically connected to the four cylinders (4) and the drive motor (10).

7. The pharmacokinetic experiment sample mixing device according to claim 2, characterized in that: A plurality of fixing bolts (11) are provided at the fitting positions of the drive motor (10) and the top cover (5).

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