Post-culture observation device for transplanting glioma cells in nude mouse

Abstract

A nude mouse transplantation glioma cell post-culture observation device comprises a box body, the top of the box body is provided with a downward-concave movable groove, a movable rod sliding in the vertical direction is arranged in the movable groove, two sets of sliding ways are correspondingly arranged on the inner wall of the box body, sliding rods sliding horizontally are arranged in the sliding ways, and two corresponding movable plates are arranged on the sliding rods respectively. A first sleeve and a second sleeve are correspondingly arranged on the two movable plates, inserting grooves are formed in the two sides of the box body, loading boxes are arranged in the inserting grooves in a sliding connection mode, and the loading boxes are located below the movable plates; when the movable rod is positioned in the movable groove and moves upwards, one end of the movable plate is driven to move upwards through the first sleeve and the second sleeve, so that the nude mouse positioned on the movable plate falls into the loading box below; the nude mouse taking-out device is simple and reasonable in structure, a nude mouse can be effectively and rapidly taken out, and a worker can conveniently observe the nude mouse.

Description

Technical Field

[0001] The utility model relates to the field of nude mouse experiments, in particular to a nude mouse culture observation device after glioma cells are transplanted thereto. Background Art

[0002] During nude mouse experiments, gliomas need to be transplanted into nude mice for cultivation. These cultures are typically kept in an observation box, where staff must open the lid and remove the nude mice for observation. Because more than one nude mouse can be in the box, removing each one individually is time-consuming and laborious, and the mice must be placed in the box for easy observation. Utility Model Content

[0003] The utility model aims to provide a nude mouse culture observation device after glioma cells are transplanted, so as to facilitate operators to take out the nude mice for observation.

[0004] In order to solve the above technical problems, the specific solution adopted by the utility model is:

[0005] A device for culturing and observing nude mice after transplanting glioma cells comprises a box body, a downwardly concave movable groove is provided on the top of the box body, a movable rod sliding in the vertical direction is provided in the movable groove, two sets of slides are correspondingly provided on the inner wall of the box body, each slide is provided with a horizontally sliding rod, two movable plates corresponding to each other are provided on the slide rods, a first sleeve and a second sleeve are correspondingly provided on the two movable plates, slots are provided on both sides of the box body, a slidably connected loading box is provided in the slot, and the loading box is located below the movable plate. When the movable rod is located in the movable groove and moves upward, one end of the movable plate is driven upward by the first sleeve and the second sleeve to cause the nude mouse located on the movable plate to fall into the loading box below.

[0006] The two ends of the slide rod extend along the movable plate to the inside of the slideway, and the two sides of the movable plate are located outside the slideway.

[0007] The top of the box body is equipped with a box cover.

[0008] The box body is made of transparent material.

[0009] A handle for an operator to hold is provided on one side of the loading box.

[0010] A supporting plate is correspondingly provided on the inner wall of the box body, and the supporting plate is located below the loading box and is used for supporting the loading box.

[0011] Due to the adoption of the above technical solution, the utility model has the following beneficial effects:

[0012] By arranging a movable groove on the box body and arranging a movable rod that can move up and down inside the movable groove to drive the movable plate to move, the movable plate is tilted to send the nude mice located in the movable plate into the loading box so that the staff can take them out for observation; the utility model has a simple and reasonable structure, can effectively and quickly take out the nude mice, and is convenient for the staff to observe. BRIEF DESCRIPTION OF THE DRAWINGS

[0013] Figure 1 It is a structural diagram of the utility model;

[0014] Figure 2 This is a schematic diagram of the cutaway structure of the present utility model;

[0015] Reference numerals: box body 1; movable slot 2; movable rod 3; movable plate 4; first sleeve 5; second sleeve 6; slideway 7; slide rod 8; loading box 9; handle 10; storage slot 11. DETAILED DESCRIPTION

[0016] like Figures 1 and 2 As shown, a nude mouse transplanted glioma cell culture observation device includes a square structure box 1, the top of the box 1 is open, the top of the box 1 is equipped with a box cover, the box 1 is made of a transparent material, the top of the box 1 is provided with a downwardly concave movable groove 2, the movable groove 2 is provided with a movable rod 3 sliding in the vertical direction, the inner wall of the box 1 is provided with two groups of slides 7, each group of slides 7 is correspondingly arranged on the inner wall of the box 1, the two groups of slides 7 are located on both sides of the movable groove 2, the slides 7 are provided with horizontally sliding slide rods 8, and two corresponding movable plates 4 are provided on the slide rods 8. The movable plates 4 are used to place nude mice, and the two movable plates 4 are correspondingly provided with a first sleeve 5 and a second sleeve 6. There are slots on both sides of the box 1. A slidingly connected loading box 9 is provided in the slot, and the loading box 9 is located below the movable plate 4. When the movable rod 3 is located in the movable slot 2 and moves upward, one end of the movable plate 4 is driven upward through the first sleeve 5 and the second sleeve 6 to make the nude mouse on the movable plate 4 fall into the loading box 9 below. A handle 10 for the operator to hold is provided on one side of the loading box 9. When the movable rod 3 moves upward, the slide rod 8 will also move in the slide 7. At the same time, the movable plate 4 will tilt, and the two ends of the slide rod 8 will extend along the movable plate 4 to the inside of the slide 7. Both sides of the movable plate 4 are located outside the slide 7. A corresponding support plate (not shown in the figure) is provided on the inner wall of the box body 1. The support plate is located below the loading box 9 and is used to support the loading box 9.

[0017] The method of using the utility model is briefly described as follows:

[0018] During use, a nude mouse transplanted with glioma cells is placed on the movable plate 4 for culture. When the nude mouse needs to be taken out for careful observation, the movable rod 3 is lifted. When the movable rod 3 is lifted, the first sleeve 5 and the second sleeve 6 are moved together, and the movable plate 4 is moved together, causing the movable plate 4 to tilt. At this time, the nude mouse located on the movable plate 4 will slide down along the tilt direction of the movable plate 4 and then slide into the loading box 9. The operator only needs to pull out the loading box 9 to take the nude mouse out for observation. This saves the step of opening the box cover and does not require reaching into the box 1 to grab the nude mouse.

Claims

1. A device for observing the culture of nude mice after transplantation of glioma cells, characterized by: The invention comprises a box body (1), wherein the top of the box body (1) is provided with a downwardly concave movable groove (2), a movable rod (3) sliding in the vertical direction is provided in the movable groove (2), two sets of slideways (7) are correspondingly provided on the inner wall of the box body (1), and a horizontally sliding slide rod (8) is provided in each slideway (7), and two corresponding movable plates (4) are respectively provided on the slide rods (8), and the two movable plates (4) are correspondingly provided with a first sleeve (5) and a second sleeve (6), and slots are provided on both sides of the box body (1), and a slidingly connected loading box (9) is provided in the slots, and the loading box (9) is located below the movable plate (4). When the movable rod (3) is located in the movable groove (2) and moves upward, it drives one end of the movable plate (4) to move upward through the first sleeve (5) and the second sleeve (6), so that the nude mouse located on the movable plate (4) falls into the loading box (9) below.

2. The apparatus for observing the culture of nude mice after transplantation of glioma cells according to claim 1, wherein: Both ends of the slide rod (8) extend along the movable plate (4) to the inside of the slideway (7), and both sides of the movable plate (4) are located outside the slideway (7).

3. The apparatus for observing the culture of nude mice after transplantation of glioma cells according to claim 1, wherein: The top of the box body (1) is equipped with a box cover.

4. The apparatus for observing the culture of nude mice after transplantation of glioma cells according to claim 1, wherein: The box body (1) is made of a transparent material.

5. The apparatus for observing the culture of nude mice after transplantation of glioma cells according to claim 1, wherein: A handle (10) for an operator to hold is provided on one side of the loading box (9).

6. The apparatus for observing the culture of nude mice after transplantation of glioma cells according to claim 1, wherein: A supporting plate is correspondingly provided on the inner wall of the box body (1), and the supporting plate is located below the loading box (9) and is used to support the loading box (9).

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