Disposable filler column for filtering

Abstract

The utility model discloses a disposable packing column for filtering, which comprises a column body, a liquid inlet plunger, a liquid outlet plunger, an upper sieve plate, a lower sieve plate, a top cover and a bottom cover, the liquid inlet plunger and the liquid outlet plunger are respectively arranged at the top and the bottom of the column body, the liquid inlet plunger is provided with a liquid inlet, and the liquid outlet plunger is provided with a liquid outlet. The upper sieve plate is arranged between the liquid inlet plunger and the adsorbent, the lower sieve plate is arranged between the liquid outlet plunger and the adsorbent, the top cover is fixedly mounted at the top end of the column body, and the bottom cover is fixedly mounted at the bottom end of the column body. The disposable packing column disclosed by the utility model can be directly used, so that the processes of filling, digging and assembling the packing are saved, odor and dust are prevented from escaping, and the pollution to the working environment and the potential safety hazard are avoided; in addition, the manufacturing cost is low, and the device can be directly discarded after being used, so that the use cost is not increased, the cleaning link is saved, and the manual operation energy and cost are further saved.

Description

Technical Field

[0001] The utility model relates to the technical field of biopharmaceutical and chemical production equipment, in particular to a disposable packing column for filtration. Background Art

[0002] In the production process of chemical products or medicines, filtration is one of the common operations. To implement this filtration process in the factory, it is often necessary to use a chromatography column for operation. The column is mainly made of metal materials such as stainless steel and Hastelloy, and its preparation cost is relatively high. Therefore, it is not a disposable consumable. Instead, before each use, the cover needs to be opened to fill and dig out the filler, which is time-consuming and labor-intensive, and will cause odor and dust to escape, affecting the working environment and posing a safety hazard to the health of the workers. Therefore, how to avoid opening the cover to dig out the filler and filler, and thus avoid the escape of odor and dust, has become a technical problem that needs to be solved in this field. Utility Model Content

[0003] The technical problem to be solved by the utility model is to provide a disposable packing column for filtration, which does not require opening the cover to perform the packing and filling agent digging operation, thereby avoiding the escape of odor and dust, having no impact on the working environment, and effectively improving the impact of safety hazards on operators.

[0004] In order to solve the above technical problems, the utility model provides a disposable packing column for filtration, comprising

[0005] a column filled with an adsorbent;

[0006] a liquid inlet plunger mounted on the top of the column, wherein the liquid inlet plunger is provided with a liquid inlet;

[0007] a liquid outlet plunger, which is installed at the bottom of the column, and the liquid outlet plunger is provided with a liquid outlet;

[0008] an upper sieve plate installed between the liquid inlet plunger and the adsorbent;

[0009] a lower sieve plate installed between the liquid outlet plunger and the adsorbent;

[0010] a top cover, which is fixedly mounted on the top end of the column;

[0011] The bottom cover is fixedly mounted on the bottom end of the column.

[0012] Preferably, the top cover is fastened to the top end of the column by a clamp.

[0013] Preferably, the top cover is connected to the top end of the column through threads.

[0014] Preferably, the bottom cover is fastened to the bottom end of the column by a clamp.

[0015] Preferably, the bottom cover is connected to the bottom end of the column through threads.

[0016] Preferably, a sealing ring is provided between the outer wall of the liquid inlet plunger and the inner wall of the column.

[0017] Preferably, a sealing ring is provided between the outer wall of the liquid outlet plunger and the inner wall of the column.

[0018] Preferably, the sieve hole diameter of the upper sieve plate is smaller than the particle diameter of the adsorbent.

[0019] Preferably, the sieve hole diameter of the lower sieve plate is smaller than the particle size of the adsorbent.

[0020] The utility model provides a disposable packing column that can be used directly during filtration, thus saving the processes of packing, digging and assembling, reducing workload, and preventing the escape of odor and dust, thereby avoiding pollution to the working environment and potential safety hazards to operators. In addition, since the packing column is made of one of PP (polypropylene), PTFE (polytetrafluoroethylene) or PC (polycarbonate) materials, its manufacturing cost is low and it can be directly discarded after use, which does not lead to an increase in the use cost, saves the cleaning process, and further saves manpower, energy and cost. BRIEF DESCRIPTION OF THE DRAWINGS

[0021] In order to more clearly illustrate the technical solution of the present invention, the following is a brief introduction to the drawings required for the present invention. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying any creative work.

[0022] Figure 1 This is a schematic diagram of an embodiment of a disposable packing column for filtration of the present invention;

[0023] Figure 2 This is a cross-sectional view of an embodiment of a disposable packing column for filtration according to the present invention;

[0024] In the figure, 1-column; 2-liquid inlet plunger; 21-liquid inlet; 3-liquid outlet plunger; 31-liquid outlet; 4-upper sieve plate; 5-lower sieve plate; 6-top cover; 7-bottom cover; 8-sealing ring. DETAILED DESCRIPTION

[0025] The following is a clear and complete description of the technical solutions of the present invention in conjunction with the accompanying drawings. Obviously, the embodiments described are only part of the embodiments of the present invention, not all of them. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making any creative efforts are within the scope of protection of the present invention.

[0026] refer to Figure 1 and 2 , shows a disposable packing column for filtration of the utility model, comprising

[0027] a column filled with an adsorbent;

[0028] a liquid inlet plunger mounted on the top of the column, wherein the liquid inlet plunger is provided with a liquid inlet;

[0029] a liquid outlet plunger, which is installed at the bottom of the column, and the liquid outlet plunger is provided with a liquid outlet;

[0030] an upper sieve plate installed between the liquid inlet plunger and the adsorbent;

[0031] a lower sieve plate installed between the liquid outlet plunger and the adsorbent;

[0032] a top cover, which is fixedly mounted on the top end of the column;

[0033] A bottom cover, which is fixedly mounted on the bottom end of the column;

[0034] Wherein, the column, the liquid inlet plunger, the liquid outlet plunger, the upper sieve plate, the lower sieve plate, the top cover and the bottom cover are made of one of PP, PTFE or PC materials.

[0035] The disposable packing column for filtration provided by the embodiment of the present invention has a top cover for blocking the top end of the column body and limiting the liquid inlet plunger between the top cover and the adsorbent, preferably the top cover has a through hole for the liquid inlet to pass through; the bottom cover is used to block the bottom end of the column body and limiting the liquid outlet plunger between the bottom cover and the adsorbent, preferably the bottom cover has a through hole for the liquid outlet to pass through; at the same time, in order to protect the adsorbent and prevent the reaction liquid from impacting the adsorbent, an upper sieve plate is added between the liquid inlet plunger and the adsorbent, preferably the sieve hole diameter of the upper sieve plate is smaller than the particle size of the adsorbent to prevent the adsorbent from passing through the upper sieve plate; in order to intercept the adsorbent, a lower sieve plate is added between the liquid outlet plunger and the adsorbent, and the sieve hole diameter of the lower sieve plate is limited to be smaller than the particle size of the adsorbent to prevent the adsorbent from passing through the lower sieve plate and causing contamination of the filtrate; the sizes of the upper sieve plate and the lower sieve plate are preferably matched with the inner diameter of the column, that is, the upper sieve plate and the lower sieve plate can be placed against the wall in the column to prevent the adsorbent from passing between the edges of the upper sieve plate and the lower sieve plate and the inner wall of the column. The disposable packing column for filtration provided by the utility model can be filled with adsorbent and assembled in advance at the factory end where it is produced. When filtering is required during the production process of chemical products or medicines, the liquid inlet is connected to the liquid outlet device and the liquid outlet is connected to the receiving device, and the column can be used directly, which saves the process of packing, digging and assembling, reduces the workload, and does not have the escape of odor and dust, avoids the pollution caused to the working environment, and also avoids the potential safety hazards caused to the operators; in addition, since the packing column is made of one of PP, PTFE or PC materials, its manufacturing cost is low and it can be directly discarded after use, which does not lead to an increase in the cost of use and saves the cleaning process, further saving manpower and cost. It should be noted that the physicochemical properties of materials such as PP, PTFE and PC are stable and will not contaminate the filtered material. Without being bound by this, the packing column of the utility model can also be equipped with a nitrogen inlet and a vent. It should also be noted that the adsorbent can be selected as needed, for example, it can be powder particles such as diatomaceous earth, silica gel, molecular sieve, resin, etc.

[0036] In a specific embodiment, the top cover is fastened to the top of the column via a clamp. It is understood that during the filtration process, a certain pressure is generated within the column, and therefore, the top cover needs to be fastened to the column to ensure the normal filtration process. Similarly, the bottom cover is preferably fastened to the bottom of the column via a clamp. If this restriction is not desired, the top cover can also be screwed to the top of the column, and the bottom cover can be screwed to the bottom of the column.

[0037] In a specific embodiment, a sealing ring is provided between the outer wall of the liquid inlet plunger and the inner wall of the column, and preferably, a sealing ring is provided between the outer wall of the liquid outlet plunger and the inner wall of the column. It is understood that the addition of the sealing ring can effectively enhance the sealing performance of the packing column of the present invention, effectively preventing leakage of filtrate from between the liquid inlet plunger and the inner wall of the column, and between the liquid outlet plunger and the inner wall of the column, thereby enhancing the filtration effect.

[0038] The above description is only a preferred embodiment of the present invention and is not intended to limit the scope of protection of the present invention. Any modifications, equivalent replacements, improvements, etc. made within the spirit and principles of the present invention should be included in the scope of protection of the present invention.

Claims

1. A disposable packing column for filtration, characterized in that: include: a column filled with an adsorbent; a liquid inlet plunger mounted on the top of the column, wherein the liquid inlet plunger is provided with a liquid inlet; a liquid outlet plunger, which is installed at the bottom of the column, and the liquid outlet plunger is provided with a liquid outlet; an upper sieve plate installed between the liquid inlet plunger and the adsorbent; a lower sieve plate installed between the liquid outlet plunger and the adsorbent; a top cover, which is fixedly mounted on the top end of the column; A bottom cover, which is fixedly mounted on the bottom end of the column; Wherein, the column, the liquid inlet plunger, the liquid outlet plunger, the upper sieve plate, the lower sieve plate, the top cover and the bottom cover are made of one of PP, PTFE or PC materials.

2. The disposable packed column for filtration according to claim 1, wherein The top cover is fastened to the top end of the column through a clamp.

3. The disposable packed column for filtration according to claim 1, wherein The top cover is connected to the top end of the column through threads.

4. The disposable packed column for filtration according to claim 1, wherein The bottom cover is fastened to the bottom end of the column through a clamp.

5. The disposable packed column for filtration according to claim 1, wherein The bottom cover is connected to the bottom end of the column through threads.

6. The disposable packed column for filtration according to claim 1, wherein A sealing ring is provided between the outer wall of the liquid inlet plunger and the inner wall of the column.

7. The disposable packed column for filtration according to claim 1, wherein A sealing ring is provided between the outer wall of the liquid outlet plunger and the inner wall of the column.

8. The disposable packed column for filtration according to claim 1, wherein The sieve hole diameter of the upper sieve plate is smaller than the particle diameter of the adsorbent.

9. The disposable packed column for filtration according to claim 1, wherein The sieve hole diameter of the lower sieve plate is smaller than the particle diameter of the adsorbent.

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