Chromatographic filler purification material filling device

Abstract

The utility model provides a chromatographic packing purification material filling device which comprises a base and a vibration filling mechanism, a clamp shell is arranged on the surface of the outer side of a connecting rotating shaft, a clamping spring is arranged in the clamp shell, a clamping block is arranged at the tail end of the clamping spring, a protection pad is arranged on the surface of the clamping block, and vibration springs are arranged at the inner ends of the two sides of the clamp shell. The vibration motors are arranged on the two sides of the clamp shell, the fixing rotary knobs can adjust the longitudinal position of the sliding block to adapt to chromatographic columns of different lengths, the vibration motors enable the clamp shell to vibrate through the vibration springs, filler in the chromatographic columns is evenly distributed, and the vibration springs can enable the clamp shell to return to the original position after the clamp shell stops vibrating. According to the technical scheme, the filler distribution uniformity and stability are ensured, in the whole process, the base and the fixing plate provide stable support through the welding structure, so that unnecessary displacement caused by vibration in the operation process of equipment is avoided, and through the arrangement, uniform vibration filling of the filler of the chromatographic column can be realized, and the filler quality is improved.

Description

Technical Field

[0001] The utility model relates to the technical field of filler filling, in particular to a chromatographic filler purification material filling device. Background Art

[0002] The chromatographic column generates pressure through a pump to increase the elution rate of the mobile phase through the stationary phase filler in the column, thereby accelerating the separation and purification of samples mixed with the mixture. Since the solubility of each component in the mixture in the stationary phase and the mobile phase is different, each component will flow through the stationary phase filler at a different rate, thereby achieving the purpose of separation. Filling the chromatographic column with filler is a necessary step in making the chromatographic column.

[0003] According to the search announcement number: CN203525370U, a chromatographic column packing structure includes a packing container, an adjustment component and a vacuum pump, wherein the packing container is filled with packing; the column body of the chromatographic column is hollow and cylindrical, one end of which is connected to one end of a flexible hose via a connecting joint, the other end of the flexible hose is connected to the vacuum pump, the other end of the column body is open and extends into the packing container, and the packing is adsorbed into the column body under the action of the vacuum pump; the adjustment component is L-shaped and is fixedly connected by a vertical plate and a horizontal plate; the vertical plate is provided with a plurality of notches of different heights from top to bottom. The chromatographic column packing structure of the utility model has a simple structure and low cost, and can quickly and efficiently realize the packing of the chromatographic column without the packing flying or leaking, saving time and effort.

[0004] However, the following problems exist when implementing the above technical solution: when the filler particles have large differences in size and fluidity during filling, the filler will be unevenly distributed in the chromatographic column, affecting the column efficiency, and it is impossible to effectively process chromatographic columns of different diameters. Utility Model Content

[0005] The purpose of the utility model is to provide a chromatographic filler purification material filling device to solve the problems in the above background technology.

[0006] To achieve the above-mentioned purpose, the utility model provides the following technical solutions: a chromatographic filler purification material filling device, comprising a base and a vibrating filling mechanism, a fixed plate is provided on the top of the base, a vibrating filling mechanism is provided on one side of the fixed plate, a slide groove is provided on one side of the fixed plate, a slider is provided inside the slide groove, fixed knobs are provided on both sides of the slider, a connecting shaft is provided on the right side of the slider, a clamp housing is provided on the outer surface of the connecting shaft, a clamping spring is provided inside the clamp housing, a clamping block is provided at the end of the clamping spring, a protective pad is provided on the surface of the clamping block, vibration springs are provided at the inner ends of both sides of the clamp housing, and vibration motors are provided on both sides of the clamp housing.

[0007] Preferably, the base and the fixing plate are welded, and the base provides stable support for the fixing plate.

[0008] Preferably, the chute and the slider are in sliding connection, and the inner diameter of the chute matches the outer diameter of the slider.

[0009] Preferably, the slider is threadedly connected to the fixed knob, and the slider is fixed and limited by the fixed knob and the fixed plate.

[0010] Preferably, the fixture housing is connected to the slider in a rotationally movable manner via a connecting shaft, the vibration spring and the slider are welded, and the vibration spring and the fixture housing are welded.

[0011] Preferably, the clamp housing and the clamping spring are welded, and the clamping spring and the clamping block are welded.

[0012] Preferably, the clamping block and the protective pad are adhesively connected, and the clamping block and the protective pad are tightly fitted.

[0013] Compared with the prior art, the beneficial effects of the present invention are:

[0014] The longitudinal position of the slider can be adjusted by the fixing knob to adapt to chromatographic columns of different lengths. The vibration motor vibrates the fixture housing through the vibration spring to evenly distribute the filler in the chromatographic column. The vibration spring can restore the fixture housing to its original position after the vibration of the fixture housing stops, ensuring the uniformity and stability of the filler distribution. During the whole process, the base and the fixed plate provide stable support through the welding structure, so that the equipment will not produce unnecessary displacement due to vibration during operation. Through the above settings, the filler of the chromatographic column can be evenly vibrated and filled, thereby improving the quality of the filler. BRIEF DESCRIPTION OF THE DRAWINGS

[0015] Figure 1 This is a schematic diagram of the overall appearance structure of the utility model;

[0016] Figure 2 This is a schematic diagram of the enlarged structure of point A of the utility model;

[0017] Figure 3 This is a schematic diagram of the cross-sectional structure of the clamp housing, clamping spring and clamping block of the utility model;

[0018] Figure 4 This is a schematic diagram of the cross-sectional structure of the fixed plate, sliding groove, slider and fixed knob of the utility model.

[0019] Numbers in the figure: 1, base; 2, fixed plate; 3, vibration filling mechanism; 301, slide groove; 302, slider; 303, fixing knob; 304, connecting shaft; 305, clamp housing; 306, clamping spring; 307, clamping block; 308, protective pad; 309, vibration spring; 310, vibration motor. DETAILED DESCRIPTION

[0020] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the embodiments described are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative efforts are within the scope of protection of the present invention.

[0021] See also Figure 1-4 The utility model provides a technical solution: a chromatographic filler purification material filling device, including a base 1 and a vibration filling mechanism 3, a fixed plate 2 is provided on the top of the base 1, a vibration filling mechanism 3 is provided on one side of the fixed plate 2, a slide groove 301 is provided on one side of the fixed plate 2, a slider 302 is provided inside the slide groove 301, and fixed knobs 303 are provided on both sides of the slider 302, a connecting shaft 304 is provided on the right side of the slider 302, a clamp housing 305 is provided on the outer surface of the connecting shaft 304, a clamping spring 306 is provided inside the clamp housing 305, a clamping block 307 is provided at the end of the clamping spring 306, a protective pad 308 is provided on the surface of the clamping block 307, vibration springs 309 are provided at the inner ends of both sides of the clamp housing 305, and vibration motors 310 are provided on both sides of the clamp housing 305.

[0022] Furthermore, the base 1 and the fixed plate 2 are welded, and the base 1 provides stable support for the fixed plate 2. Through such an arrangement, the chromatographic column can remain stable during filling, thereby improving the quality of the filler.

[0023] Furthermore, the slide groove 301 and the slider 302 are slidably connected, and the inner diameter of the slide groove 301 matches the outer diameter of the slider 302. Through such a setting, it can adapt to chromatographic columns of different lengths and sizes, is easy to adjust, and is simple to operate.

[0024] Furthermore, the slider 302 is threadedly connected to the fixing knob 303, and the slider 302 is fixed and limited by the fixing knob 303 and the fixing plate 2. Through such a setting, the slider 302 can be limited and fixed by rotating the fixing knob 303, which is convenient to operate.

[0025] Furthermore, the clamp housing 305 is connected to the slider 302 through the connecting shaft 304 to form a rotational connection, the vibration spring 309 and the slider 302 are welded, and the vibration spring 309 and the clamp housing 305 are welded. Through such an arrangement, after the vibration motor 310 is started, the clamp housing 305 can vibrate flexibly, and the vibration spring 309 allows the clamp housing 305 to return to its original position, so that the filler inside the chromatographic column vibrates evenly.

[0026] Furthermore, the clamp housing 305 and the clamping spring 306 are welded, and the clamping spring 306 and the clamping block 307 are welded. Through such an arrangement, the clamping spring 306 can adapt to chromatographic columns of different diameters and stably fix the chromatographic columns. The structure is simple and maintenance is convenient.

[0027] Furthermore, the clamping block 307 and the protective pad 308 are adhesively connected, and the clamping block 307 and the protective pad 308 fit tightly together. Through such an arrangement, the chromatographic column is protected from being scratched and damaged when being clamped and fixed, and has high safety.

[0028] Working principle: First, operate the fixing knob 303 to fix the slider 302 in the preset position of the slide groove 301, then insert the chromatographic column into the interior of the clamp housing 305, and the elastic force of the clamping spring 306 makes the clamping block 307 firmly clamp the chromatographic column to ensure that the chromatographic column is stable during the filling process, and the longitudinal position of the slider 302 can be adjusted by rotating the fixing knob 303 to adapt to chromatographic columns of different lengths. Then, start the vibration motor 310, and the vibration motor 310 causes the clamp housing 305 to vibrate through the vibration spring 309, so that the filler in the chromatographic column is evenly distributed. The vibration spring 309 can restore the clamp housing 305 to its original position after the clamp housing 305 stops vibrating, ensuring the uniformity and stability of the filler distribution. During the whole process, the base 1 and the fixing plate 2 provide stable support through the welding structure, so that the equipment will not produce unnecessary displacement due to vibration during operation. Through the above settings, the filler of the chromatographic column can be evenly vibrated and filled, improving the quality of the filler, thus completing the use process of a chromatographic filler purification material filling device.

[0029] Although the embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and variations may be made to these embodiments without departing from the principles and spirit of the present invention, and the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A chromatographic packing material purification material filling device, comprising a base (1) and a vibrating filling mechanism (3), characterized in that: A fixing plate (2) is provided on the top of the base (1), a vibration filling mechanism (3) is provided on one side of the fixing plate (2), a sliding groove (301) is provided on one side of the fixing plate (2), a slider (302) is provided inside the sliding groove (301), fixing knobs (303) are provided on both sides of the slider (302), a connecting shaft (304) is provided on the right side of the slider (302), a clamp housing (305) is provided on the outer surface of the connecting shaft (304), a clamping spring (306) is provided inside the clamp housing (305), a clamping block (307) is provided at the end of the clamping spring (306), a protective pad (308) is provided on the surface of the clamping block (307), vibration springs (309) are provided at the inner ends of both sides of the clamp housing (305), and vibration motors (310) are provided on both sides of the clamp housing (305).

2. A chromatographic filler purification material filling device according to claim 1, characterized in that: The base (1) and the fixed plate (2) are welded, and the base (1) provides stable support for the fixed plate (2).

3. A chromatographic filler purification material filling device according to claim 1, characterized in that: The slide groove (301) and the slider (302) are in sliding connection, and the inner diameter of the slide groove (301) matches the outer diameter of the slider (302).

4. A chromatographic filler purification material filling device according to claim 1, characterized in that: The slider (302) and the fixed knob (303) are threadedly connected, and the slider (302) is fixed and limited to the fixed plate (2) through the fixed knob (303).

5. The chromatographic filler purification material filling device according to claim 1, characterized in that: The clamp housing (305) is connected to the slider (302) via a rotating shaft (304) to form a rotational movable connection. The vibration spring (309) and the slider (302) are welded, and the vibration spring (309) and the clamp housing (305) are welded.

6. A chromatographic filler purification material filling device according to claim 1, characterized in that: The clamp housing (305) and the clamping spring (306) are welded, and the clamping spring (306) and the clamping block (307) are welded.

7. The chromatographic filler purification material loading device according to claim 1, characterized in that: The clamping block (307) and the protection pad (308) are adhesively connected, and the clamping block (307) and the protection pad (308) are tightly fitted.

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