Plasma disinfection device for PCR (Polymerase Chain Reaction) laboratory clothes

Abstract

The utility model discloses a plasma disinfection device for PCR (Polymerase Chain Reaction) laboratory clothes. The disinfection device comprises a cabinet body, and the cabinet body is provided with a first partition plate, a second partition plate and a third partition plate which are parallel from top to bottom; an atomizer, a liquid-phase plasma generator, a controller and a power supply are arranged on the first partition plate; a liquid-phase plasma spraying opening is formed in the lower surface of the first partition plate; a base of a clothes hanger supporting frame is arranged on the third partition plate, branch exhaust pipelines are arranged on the two sides of the base and connected with a main exhaust pipeline arranged below the third partition plate, the main exhaust pipeline is connected with a filtering device, and the filtering device is connected with an exhaust device. A support is arranged below the third partition plate, and wheels are arranged below the support. A control panel of the controller is mounted on the right side outer wall, between the first partition plate and the third partition plate, of the cabinet body; the front side of the cabinet body is provided with a door, and the door is provided with an observation window.

Description

Technical Field

[0001] The utility model relates to the field of PCR laboratory instruments, in particular to a plasma disinfection device for PCR lab coats and a use method thereof. Background Art

[0002] PCR (polymerase chain reaction) experiments are a very common technique in molecular biology laboratories, widely used in areas such as gene amplification, mutation detection, and pathogen detection. Due to the extremely stringent requirements of PCR experiments for both the environment and the samples used, contamination or cross-contamination can seriously affect the accuracy of experimental results. PCR lab coats are primarily used to protect the experimenter and prevent potential contamination during the experiment. To ensure the accuracy of experimental results and the safety of the experimenter, PCR lab coats must be kept clean. This is especially true when performing highly sensitive and precise PCR experiments, where the effects of foreign DNA, RNA, and other contaminants are essential. Therefore, disinfection of PCR lab coats is crucial.

[0003] Existing methods for disinfecting PCR lab coats include high-temperature and high-pressure sterilization, chemical disinfectant treatment, ultraviolet disinfection, and ozone disinfection. However, these methods have drawbacks. For example, frequent use of high temperature and high pressure can shorten the lifespan of lab coats or damage them; chemical disinfectants have limited effectiveness in removing DNA / RNA, and prolonged use can damage the coat material; ultraviolet disinfection is limited to surfaces exposed to light, and insufficient exposure time can lead to incomplete disinfection, while prolonged exposure can cause the coat material to age, discolor, or become brittle; the strong oxidizing properties of ozone can shorten the lifespan of lab coats, and its uneven distribution in confined spaces can lead to incomplete disinfection.

[0004] In view of this, the purpose of the present invention is to provide a plasma disinfection device for PCR lab coats, which uses liquid-phase plasma to disinfect the PCR lab coats that need to be disinfected to eliminate foreign DNA, RNA or other contaminants, so as to fully ensure the safety of PCR experimenters and the reliability of the results of their high-sensitivity and high-precision PCR experiments. Utility Model Content

[0005] The technical problem to be solved by the present invention is to overcome the deficiencies of existing disinfection technology for PCR lab coats and to provide a plasma disinfection device for PCR lab coats that can overcome or partially solve the above problems. This device can not only reduce the physical labor workload of disinfecting lab coats for the majority of PCR laboratory personnel, but also fully and effectively remove DNA / RNA contamination, making up for the shortcomings of ordinary cleaning and disinfection methods in removing cell-free DNA / RNA residues, and reducing the occurrence of false positive results in PCR experiments.

[0006] In order to achieve the above object, the technical solution of the utility model is:

[0007] A plasma disinfection device for PCR lab coats, comprising a cabinet body, the cabinet body being provided with a first partition, a second partition, and a third partition arranged parallel from top to bottom; an atomizer, a liquid-phase plasma generator, a controller, and a power supply being provided on the first partition body; a liquid-phase plasma spray port being provided below the first partition body and connected to the second partition body; a base for a hanger support frame being provided above the third partition body, branch exhaust pipes being provided on both sides of the base, the branch exhaust pipes being connected to a main exhaust pipe provided below the third partition body, the main exhaust pipe being connected to a filter device, and the filter device being connected to an exhaust device; a bracket being provided below the third partition body, and lockable wheels being provided below the bracket body; a control panel for the controller being mounted on the right outer wall of the lab coat disinfection cabinet body between the first and third partition bodies; a door being provided on the front side of the lab coat disinfection cabinet body, the door being provided with an observation window. Compared with the existing PCR lab coat disinfection technology solutions, the plasma disinfection device for PCR lab coats provided by the utility model can not only reduce the physical labor workload of lab coat disinfection for the majority of PCR laboratory personnel, but also can fully and effectively remove DNA / RNA contamination, make up for the shortcomings of ordinary cleaning and disinfection methods in removing cell-free DNA / RNA residues, and reduce the occurrence of false positive results in PCR experiments.

[0008] According to the embodiments of the present invention, the present invention can be further optimized. The following is the technical solution formed after optimization:

[0009] In a preferred embodiment, a plasma disinfection device for PCR lab coats comprises an ultrasonic atomizer that uses ultrasonic vibrations to break water into tiny droplets. Piezoelectric crystals, under the action of an electric current, generate high-frequency vibrations, causing water molecules to break apart on the surface and form a fine mist.

[0010] In a preferred embodiment, a plasma disinfection device for PCR lab coats is provided, wherein the atomizer is an air atomizer (two-fluid atomizer) that uses compressed air to cut a water stream into small droplets. Fine droplets are generated by mixing high-pressure air and water at a nozzle.

[0011] In one preferred embodiment, a plasma disinfection device for PCR lab coats is provided, wherein the atomizer is a centrifugal atomizer, which throws water out through a high-speed rotating disk or wheel, and the water is decomposed into fine droplets under the action of centrifugal force.

[0012] In one preferred embodiment, a plasma disinfection device for PCR lab coats is provided, wherein the atomizer is a pressure-type atomizer, which uses a high-pressure pump to pressurize water and sprays it through a fine nozzle, where the water flow is accelerated and broken into fine droplets.

[0013] In one preferred embodiment, a plasma disinfection device for PCR lab coats is provided, wherein the atomizer is an electrothermal evaporation atomizer, which heats water to boiling through a heating element, and the water vapor evaporates rapidly after heating to form mist, which is then blown away by a fan.

[0014] In one preferred embodiment, a plasma disinfection device for PCR lab coats is provided, wherein the atomizer is a rotary atomizer, which disperses water into droplets by using a rotating head through an electric or pneumatically driven rotating component.

[0015] In a preferred embodiment, a plasma disinfection device for PCR lab coats includes a liquid-phase plasma generator comprising an atomized water inlet, which allows atomized water to pass between two electrodes of the liquid-phase plasma generator to generate liquid-phase plasma. In a preferred embodiment, the atomized water inlet is connected to the atomizer via an atomized water pipeline. In a preferred embodiment, the atomized water inlet is the atomized water outlet of the atomizer. In a preferred embodiment, the atomized water inlet is an atomizing nozzle.

[0016] In one preferred embodiment, a plasma disinfection device for PCR lab coats comprises a liquid-phase plasma generator comprising two parallel electrodes. In one preferred embodiment, the electrodes are mesh electrodes, fabricated by punching or etching a tungsten nitride substrate to form a grid structure. The mesh electrode has a length, width, and thickness of 20 cm x 20 cm x 1 mm, a mesh size of 1 mm x 1 mm, a spacing between the mesh electrodes of 1-3 cm, and an operating voltage of 25-100 V. In one preferred embodiment, the electrodes are electrode arrays, fabricated by depositing a tungsten phosphide nanoarray on a boron nitride substrate using a gas-phase plasma. The electrode array has a length, width, and thickness of 20 cm x 20 cm x 3 mm, a spacing of 0.01 μm, and a spacing between the electrodes of 2-6 cm. The operating voltage of the electrode array is 50-150 V.

[0017] In one preferred embodiment, a plasma disinfection device for PCR lab coats comprises a liquid-phase plasma outlet connected to two electrodes included in the liquid-phase plasma generator, allowing the generated liquid-phase plasma to enter the connected liquid-phase plasma shower outlet through the liquid-phase plasma outlet. In one preferred embodiment, the liquid-phase plasma outlet is a circular outlet made of a permanent magnet (NdFeB) that provides a magnetic field aligned with the direction of the liquid-phase plasma. In one preferred embodiment, the liquid-phase plasma outlet is a circular outlet made of a permanent magnet (SmCo) that provides a magnetic field aligned with the direction of the liquid-phase plasma. In one preferred embodiment, the liquid-phase plasma outlet is a circular outlet made of a hybrid permanent magnet (NdFeB) and SmCo) with a mass percentage of SmCo ranging from 1% to 25%, providing a magnetic field aligned with the direction of the liquid-phase plasma. In one preferred embodiment, the liquid-phase plasma outlet is a toroidal electromagnetic coil that generates the magnetic field, and the magnetic field strength of the electromagnetic coil is controlled by adjusting the current to dynamically regulate the liquid-phase plasma.

[0018] In a preferred embodiment, a plasma disinfection device for PCR lab coats includes a liquid-phase plasma spray nozzle with a trapezoidal design to ensure that the liquid-phase plasma is evenly distributed throughout the disinfection area. In a preferred embodiment, the liquid-phase plasma spray nozzle is made of stainless steel. In a preferred embodiment, the liquid-phase plasma spray nozzle is made of titanium alloy. In a preferred embodiment, the liquid-phase plasma spray nozzle is made of engineering plastic. In a preferred embodiment, the engineering plastic is PTFE.

[0019] In one preferred embodiment, a plasma disinfection device for PCR lab coats comprises a controller that has the function of multi-device linkage control, and the controller is a programmable logic controller, a distributed control system controller, an embedded controller, or an intelligent controller. In one preferred embodiment, the multi-device linkage control functions include: controlling the on / off and operating time of the atomizer; controlling the start / stop and output intensity of the liquid-phase plasma generator; monitoring the status of the liquid-phase plasma output port to ensure normal operation of the device; monitoring the ventilation of the exhaust pipe; and controlling the exhaust process. In one preferred embodiment, the multi-device linkage control functions include: setting the disinfection cycle, including the duration of atomization and plasma treatment, and timing the start and stop of the disinfection program. In one preferred embodiment, the multi-device linkage control functions include: safety monitoring and alarming, real-time monitoring of the power status of the device to prevent overload or failure; real-time monitoring of the alarm status of the temperature and humidity sensors of different devices to ensure the safety and effectiveness of the operating environment; and issuing an alarm and automatically stopping the device in the event of an abnormality (such as exhaust pipe blockage, atomizer failure, or liquid-phase plasma generator failure). In one preferred embodiment, the multi-device linkage control function includes: setting various parameters such as disinfection time and plasma intensity through a human-machine interface, and displaying the operating status and parameters of the equipment in real time. The human-machine interface is a control panel. In one preferred embodiment, the multi-device linkage control function includes: remote monitoring and data logging. It can be connected to the network to remotely monitor the equipment status and record the operating parameters and time of each disinfection for tracking and review.

[0020] In one preferred embodiment, a plasma disinfection device for PCR lab coats, the PLC program code run by the controller is:

[0021] , Code explanation: (1) Start button: Starts the entire disinfection process, including the atomization, plasma disinfection, and exhaust steps. (2) Stop button: Can be used to abort the operation at any time. (3) Atomizer, plasma generator, and exhaust pipeline: Start and stop in sequence according to the set time sequence. (4) Safety monitoring: If a safety fault is detected, the program will automatically stop all equipment and issue an alarm. (5) The disinfection time and exhaust time in the code can be adjusted.

[0022] In one preferred embodiment, a plasma disinfection device for PCR lab coats, the python program code run by the controller is:

[0023] , Code Explanation: (1) start_disinfection: Starts the disinfection process, including starting the atomizer and plasma generator. (2) stop_disinfection: Stops all equipment. (3) start_exhaust / stop_exhaust: Controls the start and stop of the exhaust line. (4) safety_check: Monitors the safety status and triggers an alarm and shuts down all equipment if a fault occurs. (5) run: Main control logic, used to simulate the disinfection and exhaust processes. (6) The disinfection time and exhaust time in the code can be adjusted.

[0024] In one preferred embodiment, a plasma disinfection device for PCR lab coats, the controller runs the following C language program code:

[0025] , Code explanation: (1) Global state variables: In C language, the bool type (defined in stdbool.h) is used to represent the state of the device. Each state variable is declared in the global scope so that all functions can access and modify it. (2) Timer: The sleep_seconds function is a function that simulates time.sleep(). It implements delay by comparing the current time with the start time. (3) Function: All major functions are encapsulated in their respective functions, such as starting the disinfection program, stopping the program, starting exhaust, and triggering the alarm. (4) Main function: The main() function is the entry point of the program, which calls the run() function to execute the logic. (5) The disinfection time and exhaust time in the code can be adjusted.

[0026] In one preferred embodiment, a plasma disinfection device for PCR lab coats, the controller runs the following LABVIEW graphics program:

[0027] .

[0028] In one preferred embodiment, a plasma disinfection device for PCR lab coats, the controller is a Siemens S7-1200 or S7-1500. In one preferred embodiment, a plasma disinfection device for PCR lab coats, the controller is a Mitsubishi Electric FX5U or Q series. In one preferred embodiment, a plasma disinfection device for PCR lab coats, the controller is an Omron CP1H or CJ2M. In one preferred embodiment, a plasma disinfection device for PCR lab coats, the controller is a Schneider Electric Modicon M241 or M251.

[0029] In a preferred embodiment, a plasma disinfection device for PCR lab coats comprises a power supply including an external power supply and a reserve power supply. In the event of a power outage or when there is no external power supply, the reserve power supply can be used for power supply.

[0030] In one preferred embodiment, a plasma disinfection device for a PCR lab coat, wherein the material of the first partition is a high-strength steel plate or a composite material. In one preferred embodiment, a plasma disinfection device for a PCR lab coat, wherein the material of the first partition is Q690 high-strength structural steel, and the tensile strength is greater than or equal to 690 MPa. In one preferred embodiment, a plasma disinfection device for a PCR lab coat, wherein the material of the first partition is S355 high-strength steel plate, and the tensile strength is 470-630 MPa. In one preferred embodiment, a plasma disinfection device for a PCR lab coat, wherein the material of the first partition is AH36 shipbuilding steel plate, and the tensile strength is 490-620 MPa. In one preferred embodiment, a plasma disinfection device for a PCR lab coat, wherein the material of the first partition is a carbon fiber composite material, and the tensile strength is greater than or equal to 1500 MPa. In one preferred embodiment, a plasma disinfection device for a PCR lab coat, wherein the material of the first partition is a glass fiber reinforced composite material, and the tensile strength is about 1000 MPa. In one preferred embodiment, a plasma disinfection device for PCR lab coats, wherein the first partition is made of a glass fiber reinforced composite material having a tensile strength of Kevlar fiber composite material and a tensile strength greater than or equal to 3000 MPa.

[0031] In one preferred embodiment, a plasma disinfection device for PCR lab coats is provided with a channel for a liquid plasma outlet on the first partition so that the liquid plasma outlet is connected to a liquid plasma spray port provided below the first partition. In one preferred embodiment, the connection method is a flange connection, in which a strong seal is achieved by bolts, flanges and sealing gaskets, and the material of the sealing gaskets is rubber or polytetrafluoroethylene, etc. In one preferred embodiment, the connection method is a welding connection. In one preferred embodiment, the connection method is a quick connector connection, in which the connection is achieved by a snap or quick locking device, and the material of the quick connector is metal, stainless steel or high-strength plastic. In one preferred embodiment, the connection method is a clamp connection, in which fixation is achieved by clamping. In one preferred embodiment, the connection method is a threaded connection, in which fixation is achieved by rotating and tightening, and the sealing of the connection can be further enhanced by sealing materials such as sealing tape and O-rings. In one preferred embodiment, the connection method is a flexible pipe connection.

[0032] In one preferred embodiment, a plasma disinfection device for PCR lab coats, the second partition is a detachable movable partition, and holders for fixing the second partition are installed on the left and right sides of the lab coat disinfection cabinet.

[0033] In one preferred embodiment, a plasma disinfection device for PCR lab coats, the second partition is made of a porous silicon nitride material, and the pore size of the porous silicon nitride material is between 0.001 and 0.5 microns. In one preferred embodiment, the pore size of the porous silicon nitride material is 0.0015 microns. In one preferred embodiment, the pore size of the porous silicon nitride material is 0.002 microns. In one preferred embodiment, the pore size of the porous silicon nitride material is 0.0021 to 0.01 microns. In one preferred embodiment, the pore size of the porous silicon nitride material is 0.011 to 0.02 microns. In one preferred embodiment, the pore size of the porous silicon nitride material is 0.021 to 0.03 microns. In one preferred embodiment, the pore size of the porous silicon nitride material is 0.031 to 0.05 microns. In one preferred embodiment, the pore size of the porous silicon nitride material is 0.051 to 0.1 microns. In one preferred embodiment, the pore size of the silicon nitride porous material is 0.11-0.2 microns. In one preferred embodiment, the pore size of the silicon nitride porous material is 0.21-0.3 microns. In one preferred embodiment, the pore size of the silicon nitride porous material is 0.31-0.4 microns. In one preferred embodiment, the pore size of the silicon nitride porous material is 0.41-0.49 microns.

[0034] In one of the preferred embodiments, a plasma disinfection device for PCR lab coats, the second partition is connected to the liquid plasma spray port by bolt connection, and a strong seal is achieved by bolts, nuts, and sealing washers, and the material of the sealing washers is rubber or polytetrafluoroethylene, etc.

[0035] In one of the preferred embodiments, a plasma disinfection device for PCR lab coats, the second partition is connected to the liquid plasma spray port by a flange connection, and a strong seal is achieved by bolts, flange plates and sealing gaskets, and the material of the sealing gasket is rubber or polytetrafluoroethylene, etc.

[0036] In one of the preferred embodiments, a plasma disinfection device for a PCR lab coat, the second partition and the liquid plasma spray port are connected by a quick connector, which is connected by a snap or a quick locking device, and the quick connector is made of metal, stainless steel or high-strength plastic.

[0037] In one preferred embodiment, a plasma disinfection device for PCR lab coats, the second partition is connected to the liquid phase plasma spray port by a clamp connection and is fixed by clamping.

[0038] In one preferred embodiment, a plasma disinfection device for PCR lab coats is provided below the second partition plate, wherein a grid carrier is provided for laying the lab coats flat so as to be evenly treated by plasma; and a support frame of the grid carrier is installed on the third partition plate.

[0039] In one preferred embodiment, a plasma disinfection device for PCR lab coats, the grid carrier is a stacked design with 1-5 layers.

[0040] In one of the preferred embodiments, a plasma disinfection device for PCR lab coats is provided, wherein the grid carrier is detachable, which facilitates cleaning and allows for flexible adjustment of the number of layers to meet different disinfection requirements.

[0041] In one preferred embodiment, a plasma disinfection device for PCR lab coats, the mesh aperture of the mesh carrier is 5-10 mm, ensuring that the plasma can effectively penetrate the lab coats on each layer of the carrier.

[0042] In one preferred embodiment, a plasma disinfection device for PCR lab coats is provided, wherein the grid carrier has a height adjustment function, and the distance between layers can be adjusted according to the thickness and number of lab coats to ensure uniform plasma treatment.

[0043] In one preferred embodiment, a plasma disinfection device for PCR lab coats, the grid carrier has a slide rail design so that the height of each layer of carrier can be easily adjusted by the slide rail to maintain stability and flexibility.

[0044] In one preferred embodiment, a plasma disinfection device for PCR lab coats, the grid carrier has a buckle design so that the height of each layer of carrier can be easily adjusted by sliding the buckle to maintain stability and flexibility.

[0045] In one of the preferred embodiments, a plasma disinfection device for PCR lab coats is provided, wherein the grid carrier is modularly designed, and each layer of the carrier is an independent module that can be combined, separated, interchanged, or increased or decreased as needed, thereby facilitating the processing of lab coats of different sizes and quantities.

[0046] In one preferred embodiment, a plasma disinfection device for PCR lab coats is provided, wherein the grid carrier is designed to be non-slip and has a non-slip mesh surface to ensure that the lab coats do not slip or move during the treatment process and remain flat.

[0047] In one preferred embodiment, a plasma disinfection device for PCR lab coats is provided, wherein the grid carrier is designed with edge protection, and the grid edges are rounded to prevent the lab coats from being scratched during operation.

[0048] In one preferred embodiment, a plasma disinfection device for PCR lab coats, the material of the grid carrier is stainless steel. In one preferred embodiment, a plasma disinfection device for PCR lab coats, the material of the grid carrier is aluminum alloy.

[0049] In one preferred embodiment, a plasma disinfection device for PCR lab coats, the base of the grid carrier support frame is directly fixed on the third partition by bolts or screws.

[0050] In one preferred embodiment, a plasma disinfection device for PCR lab coats is provided below the second partition plate, and a hanger for hanging the lab coats is provided, and a support frame of the hanger is installed on the third partition plate.

[0051] In one preferred embodiment, a plasma disinfection device for PCR lab coats is provided, wherein the hanger is an arc-shaped hanger, so that the lab coat hung on the hanger maintains its shape and its surface is evenly exposed to the plasma.

[0052] In one preferred embodiment, a plasma disinfection device for PCR lab coats, the hanger is made of stainless steel. In one preferred embodiment, a plasma disinfection device for PCR lab coats, the hanger is made of Inconel 625. In one preferred embodiment, a plasma disinfection device for PCR lab coats, the hanger is made of polyetheretherketone. In one preferred embodiment, a plasma disinfection device for PCR lab coats, the hanger is made of polyimide.

[0053] In one preferred embodiment, a plasma disinfection device for PCR lab coats, the width of the hanger should be slightly larger than the width of the lab coat, and the width difference is greater than or equal to 0.1 meters.

[0054] In one preferred embodiment, a plasma disinfection device for PCR lab coats is provided, wherein the layout of the hangers is a stacked design, wherein one or more hangers are placed on each layer.

[0055] In one preferred embodiment, a plasma disinfection device for PCR lab coats is provided, wherein the hanger is a multi-layer hanger, and the distance between layers of the multi-layer hanger is greater than or equal to 0.5 meters to ensure that the clothes do not contact each other.

[0056] In one preferred embodiment, a plasma disinfection device for PCR lab coats is provided, wherein the hangers are arranged side by side in a horizontal direction, and the gap between the hangers is greater than or equal to 0.1 meters to ensure that the clothes do not touch each other.

[0057] In one preferred embodiment, a plasma disinfection device for PCR lab coats is provided, wherein the height of the hanger is flexibly adjusted by providing a height-adjustable support frame.

[0058] In one preferred embodiment, a plasma disinfection device for PCR lab coats is provided, wherein the hanger is rotated or slid by a rotating or sliding mechanism provided on the support frame to ensure that all parts of the lab coat are evenly treated by plasma.

[0059] In one of the preferred embodiments, a plasma disinfection device for PCR lab coats is provided, wherein the rotation mechanism provided on the support frame of the hanger is a bearing rotation mechanism, and a bearing is installed at the top or bottom of the support frame to be connected to the hanger, so that the hanger can rotate 360 ​​degrees through the bearing.

[0060] In one preferred embodiment, a plasma disinfection device for PCR lab coats is provided, wherein the hanger is a gear-driven mechanism provided with a rotating mechanism on a support frame, and a gear system is installed on the support frame, and the hanger is driven to rotate by a small motor.

[0061] In one of the preferred embodiments, a plasma disinfection device for PCR lab coats is provided, wherein the rotation mechanism provided on the hanger support frame is a friction wheel rotation mechanism, and a pair of friction wheels are used to clamp the rotating shaft of the hanger, and the friction wheels are driven to rotate by a motor, thereby driving the hanger to rotate.

[0062] In one of the preferred embodiments, a plasma disinfection device for PCR lab coats is provided, wherein the hanger is a slide rail and slider mechanism through a sliding mechanism provided on a support frame. A pair of parallel slide rails are installed on the support frame, and sliders are installed on the hanging part of the hanger, so that the sliders move on the slide rails and drive the hanger to slide smoothly.

[0063] In one of the preferred embodiments, a plasma disinfection device for PCR lab coats is provided, wherein the hanger is provided with a sliding mechanism as a linear guide rail and a pulley mechanism on a support frame. By using a high-precision linear guide rail system, a pulley is installed on the support frame and connected to the hanger, and the hanger slides horizontally while the pulley moves along the guide rail.

[0064] In one of the preferred embodiments, a plasma disinfection device for PCR lab coats, the hanger is a combination mechanism of rotation and sliding through a rotating or sliding mechanism provided on a support frame, a rotating bearing is installed on the top of the support frame, and slide rails are installed on the upper and bottom parts of the support frame, so that the hanger can rotate through the bearing and move horizontally through the slide rails.

[0065] In one preferred embodiment, a plasma disinfection device for PCR lab coats is provided, wherein a tensioning device is added to the crossbar of the hanger to ensure that the lab coats can be hung flat to prevent wrinkles from affecting the disinfection effect of the plasma.

[0066] In one of the preferred embodiments, a plasma disinfection device for PCR lab coats is provided, wherein the tensioning device added to the crossbar of the hanger is designed as an elastic clamp, and the elastic clamp is installed along the crossbar of the hanger to grasp the edge of the lab coat and apply tension to make it hang flat. In one of the preferred embodiments, the elastic clamps are installed on the crossbar of the hanger at regular intervals, and the elastic clamps are evenly distributed along the length of the hanger, and the distance is 5 cm to 20 cm. In one of the preferred embodiments, the elastic clamps are made of an elastic material and have an automatic closing function. In one of the preferred embodiments, the elastic material is rubber. In one of the preferred embodiments, the elastic material is spring steel.

[0067] In a preferred embodiment, a plasma disinfection device for PCR lab coats includes a tensioning device added to the crossbar of the hanger in the form of an adjustable clamp, which is secured to the crossbar via bolts. In a preferred embodiment, the adjustable clamp is secured to the crossbar via a sliding slot.

[0068] In a preferred embodiment, a plasma disinfection device for PCR lab coats includes a tensioning device attached to the crossbar of the hanger. The tensioning hooks are hook-shaped devices located at either end of the hanger or at appropriate locations. These hooks grip the edges of the lab coat and apply tension, ensuring the coat unfolds smoothly. In a preferred embodiment, the tensioning hooks are designed to have two hooks installed at each end of the hanger, with one to four hooks located in the center. In a preferred embodiment, the tensioning hooks are connected to an elastic cord, and the tension of the lab coat is adjusted by tightening the cord. In a preferred embodiment, the tensioning hooks are spring-loaded hooks that automatically adjust tension to accommodate slight movement of the lab coat during handling. In a preferred embodiment, the tensioning hooks move via a slide system to adjust to the size of the lab coat. In a preferred embodiment, the height of the tensioning hooks is adjustable to accommodate lab coats of varying lengths.

[0069] In one of the preferred embodiments, a plasma disinfection device for a PCR lab coat is provided, wherein a tensioning device is added to the crossbar of the hanger, which uses an elastic clamp and a tightening hook at the same time. The tightening hooks are used at both ends of the hanger to tighten the two ends of the lab coat outward; an elastic clamp is used in the central part of the hanger to fix the hem and sides of the lab coat to eliminate wrinkles to the greatest extent, ensuring that the lab coat always remains flat during the plasma disinfection process.

[0070] In one preferred embodiment, a plasma disinfection device for PCR lab coats, wherein the hanger is detachable in design to facilitate cleaning, maintenance and replacement, thereby improving disinfection efficiency and extending the service life of the hanger. In one preferred embodiment, the detachable hanger is composed of detachable modules, which include a crossbar, a hook, a clamp, etc. The modules are connected by snaps, bolts or quick-release devices, making it easy to disassemble and replace them individually when needed. In one preferred embodiment, the quick-release device is a quick-release button or quick-release clamp designed at the connection point. By simply pressing the button or pulling the clamp, the relevant components can be quickly disassembled, reducing assembly and disassembly time. In one preferred embodiment, the quick-release device is similar in design to a bicycle quick-release rod, which can be released by pulling and fixed by pressing. In one preferred embodiment, the crossbar and hook of the detachable hanger are connected by a plug-in connection. In one preferred embodiment, the crossbar and hook of the detachable hanger are connected by a threaded connection. In one of the preferred embodiments, a sliding slot is provided at the connection between the crossbar and the hanger body of the detachable hanger, and the hanger assembly is installed or removed by sliding. A locking mechanism is provided in the slide slot to ensure that the hanger assembly is firmly connected and easy to disassemble. In one of the preferred embodiments, the surface of the hanger assembly adopts a smooth design and is covered with an anti-fouling coating to reduce dirt adhesion and facilitate cleaning. In one of the preferred embodiments, the hanger assembly uses corrosion-resistant stainless steel or aluminum alloy to increase the service life of the hanger and reduce the frequency of maintenance. In one of the preferred embodiments, the connection points and fixing parts of the hanger assembly are hidden inside the hanger to prevent dust or pollutants from accumulating on the exposed parts.

[0071] In one of the preferred embodiments, a plasma disinfection device for PCR lab coats, the hangers are designed with standardized sizes to improve the versatility of the hangers and adapt them to a variety of lab coats and different lab environments. In one of the preferred embodiments, the standardized crossbar length of the hanger is 60cm. In one of the preferred embodiments, the standardized crossbar length of the hanger is 80cm. In one of the preferred embodiments, the standardized crossbar length of the hanger is 100cm. In one of the preferred embodiments, the crossbar of the hanger is designed as a retractable crossbar on the basis of standardization, and the length of the crossbar is adjusted by a sliding and locking mechanism to accommodate lab coats of special sizes. In one of the preferred embodiments, each standardized length position of the crossbar of the hanger is provided with a scale or positioning hole to facilitate precise adjustment.

[0072] In one of the preferred embodiments, a plasma disinfection device for PCR lab coats, the hooks of the hanger and the interfaces of the clamps are of standard size, ensuring compatibility with lab coats of different brands or models. In one of the preferred embodiments, the hooks of the hanger are of replaceable design, which can be quickly replaced with different types of hooks according to experimental requirements by fixing them. In one of the preferred embodiments, the hooks of the hanger are of replaceable design, which can be quickly replaced with different types of hooks according to experimental requirements by fixing them with snaps. In one of the preferred embodiments, the interface sizes of the clamps of the hanger and other fixing devices are unified, so that these accessories can be used interchangeably. In one of the preferred embodiments, the clamp mounting interface of the hanger can be unified to a diameter of 10 mm, ensuring that all clamps can be installed on the same crossbar.

[0073] In a preferred embodiment, a plasma disinfection device for PCR lab coats employs a telescopic support frame, similar to a common camera tripod or medical IV stand. The support frame is composed of multiple nested cylinders or square tubes, which are adjusted in height by sliding, and secured at the desired height using a locking device. This allows for quick and convenient height adjustment. In a preferred embodiment, the locking device is a knob. In a preferred embodiment, the locking device is a spring buckle. In a preferred embodiment, the locking device is a buckle.

[0074] In one of the preferred embodiments, a plasma disinfection device for PCR lab coats is provided, wherein the pillars of the support frame of the hanger are adjusted by hydraulic or pneumatic pressure. By pressing or rotating the adjustment switch, the pillars can be slowly raised and lowered, and automatically locked after being adjusted to the desired height.

[0075] In one preferred embodiment, a plasma disinfection device for PCR lab coats, the base of the support frame of the hanger is directly fixed on the third partition by bolts or screws.

[0076] In one preferred embodiment, a plasma disinfection device for PCR lab coats is provided, wherein a quick-release interface is provided at the connection between the base of the support frame of the hanger and the third partition, using a snap connection or magnetic adsorption.

[0077] In one preferred embodiment, a plasma disinfection device for a PCR lab coat, the material of the third partition is a high-strength steel plate or a composite material. In one preferred embodiment, a plasma disinfection device for a PCR lab coat, the material of the third partition is Q690 high-strength structural steel, with a tensile strength greater than or equal to 690 MPa. In one preferred embodiment, a plasma disinfection device for a PCR lab coat, the material of the third partition is S355 high-strength steel plate, with a tensile strength of 470-630 MPa. In one preferred embodiment, a plasma disinfection device for a PCR lab coat, the material of the third partition is AH36 shipbuilding steel plate, with a tensile strength of 490-620 MPa. In one preferred embodiment, a plasma disinfection device for a PCR lab coat, the material of the third partition is a carbon fiber composite material, with a tensile strength greater than or equal to 1500 MPa. In one preferred embodiment, a plasma disinfection device for a PCR lab coat, the material of the third partition is a glass fiber reinforced composite material, with a tensile strength of approximately 1000 MPa. In one preferred embodiment, a plasma disinfection device for PCR lab coats, the third partition is made of a glass fiber reinforced composite material, the tensile strength of which is Kevlar fiber composite material, and the tensile strength is greater than or equal to 3000 MPa.

[0078] In one of the preferred embodiments, a plasma disinfection device for PCR lab coats, the third partition is provided with grooves for branch exhaust pipes on both sides of each hanger support frame base or grid carrier support frame base, so that the branch exhaust pipes are connected to the main exhaust pipe provided under the third partition through the exhaust one-way valve.

[0079] In one preferred embodiment, a plasma disinfection device for PCR lab coats, the main exhaust line is connected to a filtering device, the filtering device is sequentially equipped with a drying filter, a HEPA filter and an activated carbon filter, and the filtering device is connected to an exhaust device.

[0080] In one preferred embodiment, a plasma disinfection device for PCR lab coats, the main exhaust pipe or the branch exhaust pipe is made of stainless steel.

[0081] In one preferred embodiment, a plasma disinfection device for PCR lab coats, the main exhaust pipe or the branch exhaust pipe is made of polytetrafluoroethylene.

[0082] In one preferred embodiment, a plasma disinfection device for PCR lab coats, the drying filter installed in the filtering device is an adsorption drying filter.

[0083] In one preferred embodiment, a plasma disinfection device for PCR lab coats, the drying filter installed in the filtering device is a condensation drying filter.

[0084] In one preferred embodiment, a plasma disinfection device for PCR lab coats, the drying filter installed in the filtering device is a membrane drying filter.

[0085] In one preferred embodiment, a plasma disinfection device for PCR lab coats is provided, wherein the exhaust device is designed as a directional exhaust device, and the exhaust direction is controlled by an exhaust fan.

[0086] In one preferred embodiment, a plasma disinfection device for PCR lab coats, the exhaust device is a negative pressure exhaust device.

[0087] In one of the preferred embodiments, a plasma disinfection device for PCR lab coats is provided, wherein the exhaust device is an automatic control and feedback device, which adjusts the operation of the exhaust device in real time according to the disinfection process of the lab coats and the laboratory environment, and the device uses a sensor to monitor the exhaust speed to ensure the optimal operating state of the exhaust device.

[0088] In one preferred embodiment, a plasma disinfection device for PCR lab coats is provided, wherein the exhaust device is an interlocking device, and the interlocking device can automatically stop the liquid phase plasma disinfection process when the exhaust device operates abnormally.

[0089] In a preferred embodiment, a plasma disinfection device for PCR lab coats includes a bracket disposed below the third partition plate, and lockable wheels disposed below the bracket. In a preferred embodiment, the wheels are universal wheels with brakes.

[0090] In one of the preferred embodiments, a plasma disinfection device for PCR lab coats is provided, wherein a control panel of the controller is installed on the left outer wall of the cabinet of the disinfection device between the first partition and the third partition. The control panel has a simple and intuitive operation interface, which is convenient for setting parameters (such as disinfection time, etc.) and displays the operating status and parameters of the equipment in real time.

[0091] In one preferred embodiment, a plasma disinfection device for a PCR lab coat, wherein the control panel is a Siemens TP series control panel, which provides an intuitive operating interface. In one preferred embodiment, a plasma disinfection device for a PCR lab coat, wherein the control panel is a Mitsubishi GOT series control panel, which provides a user-friendly interface. In one preferred embodiment, a plasma disinfection device for a PCR lab coat, wherein the control panel is an Omron NS series control panel, which provides a simple and easy-to-use operating interface. In one preferred embodiment, a plasma disinfection device for a PCR lab coat, wherein the control panel is a Schneider Magelis HMI control panel, which provides an intuitive control interface.

[0092] In one preferred embodiment, a plasma disinfection device for PCR lab coats has a cabinet with a front door. The door is made of stainless steel and may include a tempered glass observation window in the center to facilitate observation of the internal disinfection status. A high-efficiency sealing strip is installed around the door frame to ensure a complete seal when the door is closed. In one preferred embodiment, the sealing strip is made of EPDM. In one preferred embodiment, the sealing strip is made of silicone. In one preferred embodiment, a multi-point locking mechanism is used to ensure tight contact between the sealing strip and the door frame.

[0093] In a preferred embodiment, a plasma disinfection device for PCR lab coats has a door with an opening and closing and interlocking function. In a preferred embodiment, the opening and closing of the door is controlled by a button. In a preferred embodiment, the interlocking function prevents the door from being opened during the disinfection process and can only be unlocked and opened after disinfection is complete.

[0094] In one preferred embodiment, a plasma disinfection device for a PCR lab coat, the hinge portion of the door may adopt a balanced design to ensure that the door remains stable in any position and prevent the door from closing or opening suddenly.

[0095] A method for manufacturing a plasma disinfection device for PCR lab coats, comprising the following steps:

[0096] The first step is to configure the cabinet's bracket, wheels, and the first, second, and third partitions parallel from top to bottom to build the cabinet; the second step is to install the atomizer, liquid-phase plasma generator, controller, and power supply on the first partition in sequence, connect the controller to the atomizer and liquid-phase plasma generator respectively through signal cables, connect the power supply to the controller through power cables, and connect the power supply to the external power cord through power supply; the third step is to connect the liquid-phase plasma spray port to the liquid-phase plasma outlet of the liquid-phase plasma generator through the channel of the liquid-phase plasma outlet provided on the first partition, and then connect it to the second partition; the fourth step is to install the hanger support frame base or the grid carrier support frame base on the third partition, and install the branch exhaust pipe through the channel of the branch exhaust pipe provided on both sides of the hanger support frame base or the grid carrier support frame base, and connect it to the main exhaust pipe; the fifth step is to connect the hanger support frame base or the grid carrier support frame base to the liquid plasma outlet of the liquid plasma generator through the channel of the branch exhaust pipe provided on both sides of the hanger support frame base or the grid carrier support frame base, and connect it to the main exhaust pipe; The first step is to install the hanger support frame on the hanger support frame base and install the hanger at the same time. If a grid carrier is used to lay the lab coat, the grid carrier is installed on the grid carrier support frame base and the grid carrier is installed at the same time; the sixth step is to install the right outer wall between the first partition and the third partition, and install the control panel on the right outer wall, and connect the display screen, start switch and shutoff switch of the control panel to the corresponding pins or terminals on the controller through the control cable; the seventh step is to install the door and sealing strip on the front side of the cabinet, and the door is provided with an observation window; the eighth step is to install the outer wall and sealing strip on the left side of the cabinet, and at the same time install the outer wall and sealing strip on the rear side of the cabinet; the ninth step is to connect the main exhaust pipe to the filter device, and connect the filter device to the exhaust device; the tenth step is to connect the exhaust device to the controller through the signal cable to make a plasma disinfection device for PCR lab coats.

[0097] The working principle of a plasma disinfection device for PCR lab coats is as follows: a liquid-phase plasma generator is used to convert atomized water droplets introduced from an atomized water inlet into hydroxyl radical plasma and peroxyhydroxyl radical plasma with disinfection function through a liquid-phase plasma electrode. A liquid-phase plasma spray port connected to the liquid-phase plasma outlet is used to disinfect PCR lab coats placed on hangers or grid carriers to eliminate DNA, RNA or other contaminants. The generated exhaust gas is cleanly discharged through a drying filter, a HEPA filter and an activated carbon filter installed in the exhaust pipeline and an exhaust system provided at the end of the exhaust pipeline.

[0098] A method for using a plasma disinfection device for PCR lab coats comprises the following steps:

[0099] Step 1: Open the cabinet door, hang the lab coat to be disinfected flatly on the hanger or lay it flat on the grid carrier, and close the cabinet door; Step 2: Add deionized water to the water tank of the atomizer; Step 3: Turn on the start switch on the control panel to start the disinfection device; Step 4: After disinfection for a period of time, press the shutoff switch on the control panel to turn off the disinfection device; Step 5: Open the cabinet door, remove the lab coat from the hanger or grid carrier, and close the cabinet door; Step 6: Perform microbial inactivation and DNA / RNA residue detection on the disinfected lab coat.

[0100] Compared with the prior art, the beneficial effects of the present invention are:

[0101] (1) Filled the gap in the domestic and international use of liquid plasma disinfection equipment for PCR lab coats;

[0102] (2) Provide PCR laboratory staff with a way to disinfect the lab coats required for high-sensitivity and high-precision PCR experiments, which can reduce the physical labor burden of PCR laboratory staff in disinfection work and improve the standardized operation of lab coat disinfection for high-sensitivity and high-precision PCR experiments;

[0103] (3) The safety of PCR experimenters and the reliability of the results of their high-sensitivity and high-precision PCR experiments are fully guaranteed. BRIEF DESCRIPTION OF THE DRAWINGS

[0104] Figure 1 This is a cross-sectional view of a plasma disinfection device for a PCR lab coat according to Example 1.

[0105] Figure 2 This is a front view of a plasma disinfection device for a PCR lab coat according to Example 1.

[0106] Figure 3 This is an enlarged cross-sectional view of the branch exhaust pipe 20 of the plasma disinfection device for PCR lab coats in Example 1.

[0107] Figure 4 This is an enlarged cross-sectional view of the filter device 22 of the plasma disinfection device for PCR lab coats in Example 1.

[0108] Figure 5 This is a cross-sectional view of an outer wall 39 on the right side between the first partition 2 and the third partition 4 of the cabinet 1 of the plasma disinfection device for PCR lab coats according to Example 1, on which a control panel 26 is installed.

[0109] Figure 6 This is a cross-sectional view of the left outer wall 40 between the first partition 2 and the third partition 4 of the cabinet 1 of the plasma disinfection device for PCR lab coats in Example 1.

[0110] Figure 7 This is a cross-sectional view of the rear outer wall 41 between the first partition 2 and the third partition 4 of the cabinet 1 of the plasma disinfection device for PCR lab coats in Example 1.

[0111] Figure 8 This is a cross-sectional view of a liquid-phase plasma generator 6 of a plasma disinfection device for PCR lab coats in Example 1. DETAILED DESCRIPTION

[0112] The present invention will be described in detail below with reference to the accompanying drawings and in combination with the embodiments. It should be noted that, unless there is a conflict, the embodiments of the present invention and the features in the embodiments can be combined with each other. For the convenience of description, if "up", "down", "left", "right", "front", and "back" appear in the following text, they only indicate that they are consistent with the up, down, left, right, front, and back directions of the drawings themselves, and do not limit the structure. The embodiments of the present invention are only for explaining the present invention, not for limiting the present invention, and the embodiments of the present invention are not limited to the embodiments given in the specification. In the embodiments, if no specific experimental conditions or operating conditions are specified, they are made under conventional conditions or under the conditions recommended by the material supplier. In addition, it should be understood that one or more method steps mentioned in the present invention do not exclude the existence of other method steps before and after the combination steps or the insertion of other method steps between these explicitly mentioned steps, unless otherwise specified; it should also be understood that the combination connection relationship mentioned in the present invention does not exclude the existence of other connections before and after the combination or the insertion of other connections between the two explicitly mentioned connections, unless otherwise specified. Furthermore, unless otherwise specified, the numbering of each method step is merely a convenient tool for identifying each method step and is not intended to limit the order of the method steps or to define the scope of the present invention. Changes or adjustments to the relative relationships thereof, without substantially changing the technical content, should also be considered within the scope of the present invention. In the following examples, all reagents, materials, and instruments used are commercially available unless otherwise specified.

[0113] The utility model comprises a cabinet 1, a first partition 2, a second partition 3, a third partition 4, an atomizer 5, a liquid phase plasma generator 6, a controller 7, a power supply 8, an external power cord 9, an atomizing water pipeline 10, a signal cable 11, a signal cable 12, a power cable 13, a control cable 14, a liquid phase plasma spray port 15, a second partition buckle 16, a clothes hanger 17 or a grid carrier 17, a clothes hanger support frame 18 or a grid carrier support frame 18, a clothes hanger support frame base 19 or a grid carrier support frame base 19, a branch exhaust pipeline 20, a main exhaust pipeline 21, a filter device 22, an exhaust device 23, a signal cable 24, The bracket 25, wheels 26, control panel 27, door 28, hinges 29, door handle 30, observation window 31, exhaust check valve 32, drying filter 33, HEPA filter 34, activated carbon filter 35, display screen 36, start switch 37, shutoff switch 38, outer wall 39, outer wall 40, outer wall 41, atomized water inlet 42, liquid plasma electrode 43, liquid plasma electrode 44, liquid plasma outlet 45 and other components are all universal standard parts or components known to those skilled in the art, and their structures and principles can be known to those skilled in the art through technical manuals or through conventional experimental methods.

[0114] Example 1

[0115] A plasma disinfection device for PCR lab coats, as shown in the attached Figure 1 -Attached Figure 7 As shown, the components of the plasma disinfection device mainly include: cabinet 1, first partition 2, second partition 3, third partition 4, atomizer 5, liquid phase plasma generator 6, controller 7, power supply 8, external power line 9, atomized water pipeline 10, signal cable 11, signal cable 12, power cable 13, control cable 14, liquid phase plasma spray port 15, second partition buckle 16, hanger 17, hanger support frame 18, hanger support frame base 19, branch exhaust pipeline 20, main exhaust pipeline 21, Filter device 22, exhaust device 23, signal cable 24, bracket 25, wheel 26, control panel 27, door 28, hinge 29, door handle 30, observation window 31, exhaust check valve 32, drying filter 33, HEPA filter 34, activated carbon filter 35, display screen 36, start switch 37, stop switch 38, outer wall 39, outer wall 40, outer wall 41, atomized water inlet 42, liquid plasma electrode 43, liquid plasma electrode 44, liquid plasma outlet 45;

[0116] In Example 1, the atomizer 5 is a pressure atomizer, which is connected to the atomized water inlet 42 of the liquid phase plasma generator 6 through the atomized water pipeline 10;

[0117] In Example 1, the liquid plasma generator 6 includes two parallel liquid plasma electrodes 43 and 44, as shown in the attached figure. Figure 8 As shown. The liquid phase plasma electrode 43 and the liquid phase plasma electrode 44 are both mesh electrodes, which are made by punching or etching a tungsten nitride substrate to form a mesh structure. The length, width and thickness of the mesh electrodes are 20 cm × 20 cm × 1 mm, respectively. The mesh size of the mesh electrodes is 1 mm × 1 mm. The spacing between the mesh electrodes is 3 cm. The operating voltage of the mesh electrodes is 75 V.

[0118] In Example 1, the liquid plasma outlet 45 of the liquid plasma generator 6 is connected to the liquid plasma electrode 43 and the liquid plasma electrode 44. The liquid plasma outlet 45 is a circular outlet. The material of the liquid plasma outlet 45 is a mixed permanent magnet of neodymium iron boron and samarium cobalt, wherein the mass percentage of samarium cobalt is 5%;

[0119] In Example 1, the liquid plasma outlet 45 is connected to the liquid plasma spray port 15 of the first partition plate 1 through a flange through the channel of the liquid plasma outlet 45 provided on the first partition plate 2. A strong seal is achieved by bolts, a flange plate and a sealing gasket. The sealing gasket is made of polytetrafluoroethylene.

[0120] In Example 1, the controller 7 is a Siemens S7-1500, which runs the aforementioned PLC program code;

[0121] In Example 1, the material of the first separator 2 is Q690 high-strength structural steel with a tensile strength of 985 MPa;

[0122] In Example 1, the second partition 3 is made of a porous silicon nitride material and is fixed by a second partition buckle 16. The average pore size of the porous silicon nitride material is 0.0075 μm. The second partition 3 is connected to the liquid plasma spray port 15 by a flange connection. A strong seal is achieved by bolts, a flange plate, and a sealing gasket. The sealing gasket is made of polytetrafluoroethylene.

[0123] In Example 1, the hanger 17 is an arc-shaped hanger, the width of the hanger 17 is 1.05 meters, the material of the hanger 17 is stainless steel, the hanger gap is equal to 0.15 meters, and the hanger 17 is rotated by a bearing rotation mechanism provided on the hanger support frame 18 to ensure that all parts of the lab coat can be evenly treated by plasma. An elastic clamp is added to the crossbar of the hanger 17 and installed along the crossbar of the hanger to grasp the edge of the lab coat and apply tension. The elastic clamp is evenly distributed along the length of the hanger, and the distance is 7.5 centimeters. The elastic clamp is made of spring steel, and the crossbar length of the hanger 17 is 80 cm. The pillars of the hanger support frame 18 are adjusted by hydraulic or pneumatic pressure. By pressing or rotating the adjustment switch, the pillars can be slowly raised and lowered, and automatically locked after adjusting to the required height; the hanger support frame base 19 is directly fixed to the third partition 4 by bolts or screws;

[0124] In Example 1, the material of the third separator is S355 high-strength steel plate with a tensile strength of 550 MPa;

[0125] In Example 1, branch exhaust pipes 20 are provided on the third partitions on both sides of the hanger support frame base 19; the branch exhaust pipes 20 are provided with exhaust check valves 32;

[0126] In Example 1, a main exhaust pipe 21 is provided below the third partition plate 4. The exhaust pipe 20 is connected to the main exhaust pipe 21 via an exhaust check valve 32. The exhaust pipe is made of stainless steel.

[0127] In Example 1, the main exhaust pipe 21 is connected to the filter device 22; the filter device 22 is sequentially installed with a drying filter 33, a HEPA filter 34, and an activated carbon filter 35; the drying filter 33 is specifically a silica gel adsorption drying filter;

[0128] In Example 1, the filter device 22 is connected to the exhaust device 23, and the exhaust device 23 is an exhaust fan;

[0129] In Example 1, a bracket 25 is provided below the third partition 4, and a lockable wheel 26 is provided below the bracket 25. The wheel 26 is specifically a universal wheel with a brake device;

[0130] In Example 1, the control panel 27 is a Siemens TP control panel, and the display screen 36 is a touch screen;

[0131] In Example 1, door 28 is made of stainless steel and connected to cabinet body 1 via hinges 29. High-efficiency sealing strips are installed at the joints between door 28 and cabinet body 1 to ensure a complete seal when the door is closed. The sealing strips are made of EPDM. A door handle 30 and an observation window 31 are respectively provided in the middle of the right side of door 28 and in the center of door 28.

[0132] In Example 1, the outer wall 39 , the outer wall 40 and the outer wall 41 are all made of stainless steel.

[0133] A method for manufacturing a plasma disinfection device for PCR lab coats, comprising the following steps:

[0134] The first step is to configure the bracket 24, wheels 25, and the first partition 2, second partition 3, and third partition 4 of the cabinet 1 in parallel from top to bottom to build the cabinet 1; the second step is to install the atomizer 5, liquid phase plasma generator 6, controller 7, and power supply 8 on the first partition 2 in sequence, and connect the controller 7 to the atomizer 5 and liquid phase plasma generator 6 through signal cables 11 and 12 respectively, connect the power supply 8 to the controller 7 through power cable 13, and connect the power supply 8 to the external power line 9 through the power supply 8; the third step is to connect the liquid phase plasma The liquid spray port 15 is connected to the liquid plasma outlet 45 of the liquid plasma generator 6, and then connected to the second partition 3; the fourth step is to install the hanger base support frame base 19 on the third partition 4, and install the branch exhaust pipe 20, the exhaust check valve 32 and the main exhaust pipe 21 under the third partition 4 on both sides of the hanger support frame base 19. If a grid carrier is selected, install the grid carrier support frame base 19 on the third partition 4, and install the branch exhaust pipe 20, the exhaust check valve 32 and the main exhaust pipe 21 under the third partition 4 on both sides of the grid carrier support frame base 19. 20, exhaust check valve 32 and main exhaust pipe 21; fifth step, install the hanger support frame 18 on the hanger support frame base 19, and install the hanger 17 at the same time. If a grid carrier is selected, install the grid carrier 18 on the grid carrier support frame base 19, and install the grid carrier 17 at the same time; sixth step, install the right outer wall 39 between the first partition 1 and the third partition 3, and install the control panel 27 on the right outer wall 39, and connect the display screen 36, start switch 37, and close switch of the control panel 27 through the control cable 14. 38 is connected to the corresponding pin or terminal on the controller 7; in the seventh step, a door 28 and a sealing strip are installed on the front side of the cabinet 1, and an observation window 31 is provided on the door 28; in the eighth step, an outer wall 40 and a sealing strip are installed on the left side of the cabinet 1, and an outer wall 41 and a sealing strip are installed on the rear side of the cabinet 1; in the ninth step, the main exhaust pipe 21 is connected to the filter device 22, and the filter device 22 is connected to the exhaust device 23; in the tenth step, the exhaust device 23 is connected to the controller 7 through the signal cable 24 to make a plasma disinfection device for PCR lab coats.

[0135] A method for using a plasma disinfection device for PCR lab coats comprises the following steps:

[0136] Step 1: open the cabinet door 1, hang the lab coat to be disinfected flatly on the hanger 17 or spread it flat on the grid carrier 17, and close the cabinet door 1; Step 2: add deionized water to the water tank of the atomizer 5; Step 3: turn on the start switch 37 on the control panel 27 to start the disinfection device; Step 4: after disinfection for a period of time, press the off switch on the control panel 27 to turn off the disinfection device; Step 5: open the cabinet door 1, remove the lab coat from the hanger 17 or the grid carrier 17, and close the cabinet door 1; Step 6: perform microbial inactivation and DNA / RNA residue detection on the disinfected lab coat.

[0137] Example 2

[0138] The disinfection effect of a plasma disinfection device for PCR lab coats in Example 1 of the present invention on microbial inactivation of lab coats is evaluated according to the following process: the first step is to collect a sample on the surface of the PCR lab coat to be disinfected with a sterile cotton swab as a positive control; the second step is to place the PCR lab coat to be disinfected in the plasma disinfection device and disinfect it according to the set disinfection time; the third step is to collect a sample on the surface of the lab coat again with a sterile cotton swab after the disinfection is completed; the fourth step is to smear the collected sample on an agar medium or LB medium and culture it at 37°C for 24-48 hours; the fifth step is to observe the growth of microorganisms on the culture medium, compare the number of colonies on the surface of the PCR lab coats before and after disinfection, calculate the inactivation rate, and calculate the average inactivation rate based on the results of multiple experiments and perform statistical analysis to judge the effectiveness of the disinfection device. If the number of colonies on the surface of the PCR lab coats collected after disinfection shows no growth or a significant decrease, it indicates that the disinfection device has a significant inactivation effect on the PCR lab coat; if it does not meet the requirements, disinfection is repeated to ensure that the surface of the lab coat does not contain pollutants that affect the PCR experiment.

[0139] Example 3

[0140] The disinfection effect of a plasma disinfection device for PCR lab coats on DNA / RNA residues in Example 1 of the present invention was evaluated according to the following process:

[0141] The first step is to use a sterile cotton swab to collect a sample from the surface of the PCR lab coat to be disinfected as a positive control; the second step is to place the PCR lab coat to be disinfected in a plasma disinfection device and disinfect it according to the set disinfection time; the third step is to collect another sample from the surface of the lab coat with a sterile cotton swab after disinfection; the fourth step is to use Trizol or a commercial DNA / RNA extraction kit to extract the DNA or RNA in the sample; the fifth step is to convert the extracted RNA into cDNA through reverse transcription according to the kit instructions, and the qPCR reaction system is configured according to the instructions; the sixth step is to perform DNA / RNA amplification in a qPCR instrument and detect the fluorescence signal intensity in real time; the seventh step is to set a positive threshold based on the standard curve and calculate the amount of DNA / RNA residue in the sample collected from the surface of the PCR lab coat before and after disinfection based on the standard curve. If the amount of DNA / RNA residue is significantly reduced or undetectable, it indicates that the utility model is effective in removing residual DNA / RNA; if the requirements are not met, the lab coat must be disinfected again to ensure that the surface of the lab coat does not contain contaminants that affect the PCR experiment.

[0142] Example 4

[0143] The plasma disinfection effect of the PCR lab coats in Example 1 of the present invention was tested according to Table 1-2 below. The results are shown in Table 1-2. Six different locations on each lab coat were selected for testing. As shown in Table 1-2, the results of the disinfection effect test at different locations indicate that the present invention has a good disinfection effect on PCR lab coats.

[0144] .

[0145] Example 5

[0146] The plasma disinfection device for PCR lab coats, which is composed of four components of different specifications and produced according to the manufacturing method of the plasma disinfection device for PCR lab coats in Example 1 of the present invention, was used to test the disinfection effects of the plasma disinfection device for PCR lab coats at six different locations of the PCR lab coats. The results are summarized in Table 3. As shown in the results in Table 3, the disinfection effect requirements of the PCR lab coats are met. This illustrates the reliability of the manufacturing method of the plasma disinfection device for PCR lab coats in Example 1 of the present invention. In addition, the plasma disinfection device product for PCR lab coats produced according to the manufacturing method of the plasma disinfection device for PCR lab coats in Example 1 of the present invention can meet the disinfection needs of PCR lab coats.

[0147] Among them, the specifications of product 1 are as follows: the atomizer 5 is a pressure atomizer; the liquid plasma electrode 43 and the liquid plasma electrode 44 are both mesh electrodes, and the mesh electrode is made by punching or etching a tungsten nitride substrate to form a mesh structure. The length, width and thickness of the mesh electrode are 20 cm × 20 cm × 1 mm, respectively. The mesh size of the mesh electrode is 1 mm × 1 mm, the spacing between the mesh electrodes is 3 cm, and the operating voltage of the mesh electrode is 75 V; the liquid plasma outlet 45 is a circular outlet, and the material of the liquid plasma outlet 45 is a mixed permanent magnet of neodymium iron boron and samarium cobalt, wherein the mass percentage of samarium cobalt is 5%; the liquid plasma outlet 45 is connected to the liquid plasma spray port 15 of the first partition 1 through a flange through the channel of the liquid plasma outlet 45 provided on the first partition 2, and a strong seal is achieved by bolts, flanges and sealing gaskets. The material of the sealing gasket is polytetrafluoroethylene, and the liquid plasma spray port 15 is trapezoidal in design. The liquid plasma spray nozzle 15 is made of stainless steel; the controller 7 is a Siemens S7-1500, running the aforementioned PLC program code; the material of the first partition 2 is Q690 high-strength structural steel with a tensile strength of 985 MPa; the material of the second partition 3 is a porous silicon nitride material with an average pore size of 0.0075 microns. The second partition 3 is connected to the liquid plasma spray nozzle 15 by a flange connection, and a strong seal is achieved by bolts, flanges and sealing gaskets. The sealing gasket is made of polytetrafluoroethylene. The hanger 17 is an arc-shaped hanger with a width of 1.05 meters and is made of stainless steel. The hanger gap is equal to 0.15 meters. The hanger 17 rotates via a bearing rotation mechanism provided on the hanger support frame 18. The crossbar of the hanger 17 is equipped with elastic clamps installed along the crossbar to grasp the edge of the lab coat and apply tension. The elastic clamps are evenly distributed along the length of the hanger, and the distance between them is 7.5 cm, the elastic clamp is made of spring steel, the crossbar length of the hanger 17 is 80 cm, and the support of the hanger support frame 18 is hydraulically adjusted; the hanger support frame base 19 is directly fixed to the third partition 4 by bolts; the material of the third partition is S355 high-strength steel plate with a tensile strength of 550 Mpa; branch exhaust pipes 20 are provided on the third partitions on both sides of the hanger support frame base 19, and the branch exhaust pipes 20 are connected to the main exhaust pipe 21 through an exhaust one-way valve 32, and the exhaust pipes are all made of stainless steel; the main exhaust pipe 21 is connected to the filter device 22, and the filter device 22 is equipped with a drying filter 33, a HEPA filter 34, and an activated carbon filter 35 in sequence, and the drying filter 33 is specifically a silica gel adsorption drying filter, and the filter device 22 is connected to the exhaust device 23, and the exhaust device 23 is an exhaust fan; the bottom of the third partition 4 A bracket 25 is provided, beneath which are lockable wheels 26, specifically universal wheels with brakes. A control panel 27 is a Siemens TP control panel, and a display screen 36 is a touch screen. A door 28 is made of stainless steel and connected to the cabinet body 1 via hinges 29. The joints between the door 28 and the cabinet body 1 are both fitted with high-efficiency EPDM sealing strips. A door handle 30 and an observation window 31 are located in the middle of the right side of the door 28 and in the center of the door 28, respectively. The outer walls 39, 40, and 41 are all made of stainless steel.

[0148] The specifications of product 2 are as follows: the atomizer 5 is an ultrasonic atomizer; the liquid plasma electrode 43 and the liquid plasma electrode 44 are both mesh electrodes, and the mesh electrodes are made by punching or etching a tungsten nitride substrate to form a mesh structure. The length, width and thickness of the mesh electrodes are 20 cm × 20 cm × 1 mm, respectively. The mesh size of the mesh electrodes is 1 mm × 1 mm, the spacing between the mesh electrodes is 3 cm, and the working voltage of the mesh electrodes is 75 V; the liquid plasma outlet 45 is a circular outlet, and the liquid plasma outlet 45 is The material is neodymium iron boron permanent magnet; the liquid plasma outlet 45 is connected to the liquid plasma spray port 15 of the first partition 1 through the channel of the liquid plasma outlet 45 provided on the first partition 2 by a flange, and a strong seal is achieved by bolts, flanges and sealing gaskets. The material of the sealing gasket is polytetrafluoroethylene. The liquid plasma spray port 15 is a trapezoidal design and the material of the liquid plasma spray port 15 is stainless steel; the controller 7 is a Mitsubishi Electric FX5U, running the aforementioned Python program code; the material of the first partition 2 is S355 high-strength steel plate with a tensile strength of 600 MPa; the material of the second partition 3 is a porous silicon nitride material, and the average pore size of the porous silicon nitride material is 0.0050 microns, the connection between the second partition 3 and the liquid plasma spray nozzle 15 is a bolt connection, and a strong seal is achieved by bolts, nuts, and sealing washers. The material of the sealing washers is polytetrafluoroethylene; the grid carrier 17 is used for laying laboratory coats flat, the grid carrier 17 has 3 layers, the mesh aperture of the grid carrier 17 is 7 mm, the grid carrier 17 can adjust the layer distance according to the thickness and number of laboratory coats, and the height of each layer of the carrier can be adjusted by the slide rail. The grid carrier 17 has an anti-slip mesh surface and edge protection design. The material of the grid carrier 17 is stainless steel, and the material of the grid carrier is aluminum alloy. The grid carrier support frame base 19 is directly fixed to the third partition 4 by bolts; the material of the third partition is AH36 shipbuilding steel plate with a tensile strength of 585 MPa; A branch exhaust pipe 20 is provided on the third partition on both sides of the hanger support frame base 19, and the branch exhaust pipe 20 is connected to the main exhaust pipe 21 through an exhaust one-way valve 32. The exhaust pipe is made of stainless steel; the main exhaust pipe 21 is connected to the filter device 22, and the filter device 22 is sequentially installed with a drying filter 33, a HEPA filter 34, and an activated carbon filter 35. The drying filter 33 is specifically a silica gel adsorption drying filter. The filter device 22 is connected to the exhaust device 23, and the exhaust device 23 is an exhaust fan; the bottom of the third partition 4 A bracket 25 is provided, beneath which are lockable wheels 26, specifically universal wheels with brakes. A control panel 27 is a Mitsubishi GOT control panel, and a display screen 36 is a touch screen. Door 28 is made of stainless steel and connected to cabinet body 1 via hinges 29. High-efficiency EPDM sealing strips are installed at the joints between door 28 and cabinet body 1. A door handle 30 and an observation window 31 are located in the middle of the right side of door 28 and in the center of door 28, respectively. Outer walls 39, 40, and 41 are all made of stainless steel.

[0149] The specifications of product 3 are as follows: the atomizer 5 is an air atomizer; the liquid plasma electrode 43 and the liquid plasma electrode 44 are both electrode arrays, which are made by depositing a nano-array of tungsten phosphide on a boron nitrogen base by gas phase plasma, and the length, width and thickness of the electrode array are 20 cm × 20 cm × 3 mm respectively, the array spacing of the electrode array is 0.01 micron, the spacing between the electrode arrays is 4 cm, and the operating voltage of the electrode array is 125 V; the liquid plasma outlet 45 is a circular outlet, and the liquid plasma outlet 45 is a circular outlet. The material of the permanent magnet is samarium cobalt; the liquid plasma outlet 45 is connected to the liquid plasma spray port 15 of the first partition 1 through the groove of the liquid plasma outlet 45 provided by the first partition 2 through a flange, and a strong seal is achieved by bolts, flanges and sealing gaskets. The material of the sealing gasket is polytetrafluoroethylene, the liquid plasma spray port 15 is a trapezoidal design, and the material of the liquid plasma spray port 15 is stainless steel; the controller 7 is Omron CP1H, running the aforementioned C language program code; the material of the first partition 2 is carbon fiber composite material with a tensile strength of 1800 MPa; the second partition 3 is made of porous silicon nitride material with an average pore size of 0.0020 microns. The second partition 3 is connected to the liquid plasma spray nozzle 15 by bolts, and a strong seal is achieved by bolts, nuts, and sealing washers. The sealing washers are made of polytetrafluoroethylene. The hanger 17 is an arc-shaped hanger with a width of 1.05 meters and is made of stainless steel. The hanger gap is equal to 0.15 meters, the hanger 17 slides through the slide rail and slider mechanism provided on the hanger support frame 18. The crossbar of the hanger 17 is designed with a tensioning hook. Two tensioning hooks are installed at both ends of the hanger 17, and three hooks are configured in the center of the hanger. The tensioning hooks are spring-loaded hooks. The crossbar length of the hanger 17 is 80 cm. The support of the hanger support frame 18 is a telescopic support, and the locking device is a knob; the hanger support frame base 19 is directly fixed to the third partition 4 by bolts; the material of the third partition is Q690 high-strength structural steel with a tensile strength of 760 MPa; A branch exhaust pipe 20 is provided on the third partition on both sides of the hanger support frame base 19, and the branch exhaust pipe 20 is connected to the main exhaust pipe 21 through an exhaust one-way valve 32. The exhaust pipe is made of stainless steel; the main exhaust pipe 21 is connected to the filter device 22, and the filter device 22 is sequentially installed with a drying filter 33, a HEPA filter 34, and an activated carbon filter 35. The drying filter 33 is specifically a membrane drying filter. The filter device 22 is connected to the exhaust device 23, and the exhaust device 23 is an exhaust fan; the lower part of the third partition 4 is provided with A bracket 25 is provided, beneath which are lockable wheels 26, specifically universal wheels with brakes. A control panel 27 is an Omron NS control panel, and a display screen 36 is a touchscreen. Door 28 is made of stainless steel and connected to cabinet body 1 via hinges 29. High-efficiency silicone sealing strips are installed at the joints between door 28 and cabinet body 1. A door handle 30 and an observation window 31 are located in the middle of the right side of door 28 and in the center of door 28, respectively. Outer walls 39, 40, and 41 are all made of stainless steel.

[0150] The specifications of product 4 are as follows: the atomizer 5 is a centrifugal atomizer; the liquid plasma electrode 43 and the liquid plasma electrode 44 are both electrode arrays, which are made by depositing a nano-array of tungsten phosphide on a boron nitrogen base by gas phase plasma, and the length, width and thickness of the electrode array are 20 cm × 20 cm × 3 mm respectively, the array spacing of the electrode array is 0.01 μm, the spacing between the electrode arrays is 4 cm, and the operating voltage of the electrode array is 125 V; the liquid plasma outlet 45 is a circular outlet, and the liquid is equal to The plasma outlet 45 is made of a hybrid permanent magnet of neodymium iron boron and samarium cobalt, with the mass percentage of samarium cobalt being 10%. The liquid plasma outlet 45 is connected to the liquid plasma spray port 15 of the first partition 1 via a flange through a channel provided in the first partition 2. Bolts, a flange, and a sealing gasket are used to achieve a strong seal. The sealing gasket is made of polytetrafluoroethylene. The liquid plasma spray port 15 is a trapezoidal design and is made of stainless steel. The controller 7 is a Schneider Electric Modicon M241 running the aforementioned Labview graphics program. The first partition 2 is made of Kevlar fiber composite material with a tensile strength of 3500 MPa. The second partition 3 is made of a porous silicon nitride material with an average pore size of 0.001 micron, the connection between the second partition 3 and the liquid plasma spray port 15 is a bolt connection, and a strong seal is achieved by bolts, nuts, and sealing washers. The material of the sealing washers is polytetrafluoroethylene; the grid carrier 17 is used for laying laboratory coats flat, the grid carrier 17 has 4 layers, the mesh aperture of the grid carrier 17 is 9 mm, the grid carrier 17 can adjust the layer distance according to the thickness and number of laboratory coats, and the height of each layer of the carrier can be adjusted by buckles. The grid carrier 17 has a non-slip mesh surface and edge protection design. The material of the grid carrier 17 is stainless steel, and the grid carrier support frame base 19 is directly fixed to the third partition 4 by bolts; the material of the third partition is Kevlar Fiber composite material with a tensile strength of 3500MPa; branch exhaust pipes 20 are provided on the third partitions on both sides of the hanger support base 19, and the branch exhaust pipes 20 are connected to the main exhaust pipe 21 through an exhaust one-way valve 32, and the exhaust pipes are made of stainless steel; the main exhaust pipe 21 is connected to the filter device 22, and the filter device 22 is successively equipped with a drying filter 33, a HEPA filter 34, and an activated carbon filter 35, and the drying filter 33 is specifically a condensing drying filter, the filter device 22 is connected to the exhaust device 23, and the exhaust device 23 is a negative pressure exhaust device; a bracket 25 is provided under the third partition 4, and a lockable wheel 26 is provided under the bracket 25, and the wheel 26 is specifically a universal wheel with a brake device; the control panel 27 is a Schneider Magelis HMI control panel, display screen 36 is a touch screen; door 28 is made of stainless steel and connected to cabinet body 1 via hinges 29. The joints between door 28 and cabinet body 1 are equipped with high-efficiency silicone sealing strips with a multi-point locking mechanism. Door handle 30 and observation window 31 are located in the middle of the right side of door 28 and in the center of door 28, respectively. Outer walls 39, 40, and 41 are all made of stainless steel.

[0151] .

[0152] Example 6

[0153] Comparisons of the disinfection results of PCR lab coats using the plasma disinfection device described in Example 1 of the present invention with those using a high-temperature autoclave (Tuttnauer, Israel), an ultraviolet (Heal Force, Shanghai, China), and an ozone disinfection device (TOMI SteraMist, Maryland, USA) demonstrated comparable disinfection effectiveness. However, the present invention significantly reduced the disinfection time required to achieve the desired level of disinfection using a high-temperature autoclave (Tuttnauer, Israel), an ultraviolet (Heal Force, Shanghai, China), and an ozone disinfection device (TOMI SteraMist, Maryland, USA), respectively, significantly improving the disinfection efficiency of PCR lab coats.

[0154] The contents described in the above embodiments should be understood as these embodiments are only used to more clearly illustrate the present invention, and are not used to limit the scope of the present invention. After reading the present invention, various equivalent modifications to the embodiments by those skilled in the art fall within the scope defined by the claims attached to the present invention.

Claims

1. A plasma disinfection device for PCR lab coats, characterized in that: The disinfection device includes a cabinet, which is provided with a first partition, a second partition, and a third partition parallel from top to bottom; an atomizer, a liquid plasma generator, a controller, and a power supply are provided on the first partition; a liquid plasma spray nozzle is provided below the first partition; a support frame base for a clothes hanger is provided on the third partition, and branch exhaust pipes are provided on both sides of the support frame base, the branch exhaust pipes are connected to the main exhaust pipe provided below the third partition, the main exhaust pipe is connected to the filter device, and the filter device is connected to the exhaust device; a bracket is provided below the third partition, and wheels are provided below the bracket; a control panel of the controller is installed on the right outer wall of the cabinet between the first and third partitions; a door is provided on the front side of the cabinet, and the door is provided with an observation window.

2. The plasma disinfection device for PCR lab coat according to claim 1, characterized in that: The atomizer is an ultrasonic atomizer, an air atomizer, a centrifugal atomizer, an electrothermal evaporation atomizer or a rotary atomizer.

3. The plasma disinfection device for PCR lab coat according to claim 1, characterized in that: The electrode of the liquid-phase plasma is an electrode array, which is a nanoarray of tungsten phosphide deposited on a boron nitride base. The length, width and thickness of the electrode array are 20 cm × 20 cm × 3 mm, respectively. The array spacing of the electrode array is 0.01 micron, the spacing between the electrode arrays is 2-6 cm, and the operating voltage of the electrode array is 50-150 V.

4. The plasma disinfection device for PCR lab coat according to claim 1, characterized in that: The liquid phase plasma spray port is trapezoidal and is made of stainless steel, titanium alloy or engineering plastic.

5. The plasma disinfection device for PCR lab coats according to claim 1, characterized in that: The width of the hanger is greater than the width of the lab coat, and the width difference is greater than 0.1 meters; the height of the hanger is adjustable; the hanger can be rotated or slid; the layout of the hanger is a stacked design, multi-layer hangers or hangers arranged horizontally side by side; the material of the hanger is stainless steel, Inconel 625, polyetheretherketone or polyimide.

6. The plasma disinfection device for PCR lab coats according to claim 1, characterized in that: A tensioning device is added to the crossbar of the hanger, and the tensioning device is designed as an elastic clamp, an adjustable clamp, or a combination of an elastic clamp and a tensioning hook; the hanger is detachable, and is designed in standardized sizes, and the interfaces between the hook and the clamp of the hanger are of standard sizes.

7. The plasma disinfection device for PCR lab coats according to claim 1, characterized in that: The second partition is a detachable movable partition. The material of the second partition is a porous silicon nitride material. The average pore size of the porous silicon nitride material is 0.001-0.5 microns.

8. The plasma disinfection device for PCR lab coats according to claim 1, characterized in that: The filtering device is sequentially equipped with a drying filter, a HEPA filter and an activated carbon filter, and the drying filter is an adsorption drying filter, a condensation drying filter or a membrane drying filter.

9. The plasma disinfection device for PCR lab coats according to claim 1, characterized in that: The exhaust device is an exhaust fan or a negative pressure exhaust device.

10. The plasma disinfection device for PCR lab coats according to claim 1, characterized in that: The controller is a programmable logic controller, a distributed control system controller, an embedded controller or an intelligent controller.

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