Polyglutamic acid fermentation and purification device

By combining the fermentation chamber with the purification chamber, the direct filtration and purification of the fermentation broth is achieved, which solves the problem of equipment cleaning difficulties in the prior art and improves production efficiency.

CN223255215UActive Publication Date: 2025-08-22JIANGSU YUANSHAN BIOTECHNOLOGY CO LTD
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Patent Information

Application Number
CN202422381209.9
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-09-29
Publication Date
2025-08-22
Estimated Expiration
2034-09-29

AI Technical Summary

Technical Problem

In the prior art, the fermentation and purification operation and separation steps in the production process of polyglutamic acid are complicated, resulting in difficulty in cleaning the equipment.

Method used

A polyglutamic acid fermentation and purification device is designed, and the fermentation chamber and purification chamber are combined through a connecting device, a filtration device and a sealing device to realize direct filtration and purification of the fermentation broth and simplify the operation process.

Benefits of technology

Through the integrated fermentation and purification functions, the transfer steps are reduced, the equipment is cleaned and the production efficiency is improved.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model discloses a polyglutamic acid fermentation and purification device which comprises a purification box main body and a fermentation box main body, the fermentation box main body and the purification box main body are arranged up and down, a top cover is arranged at the upper end of the fermentation box main body, and a discharging device is fixedly connected to the lower end of the top cover. A connecting pipe is jointly arranged between the purification box main body and the fermentation box main body, the upper end of the purification box main body at the corresponding position is fixedly communicated with an input pipe, the upper end of the input pipe is fixedly connected with a filtering device, and the side wall of the input pipe is fixedly connected with a sealing device; the fermentation box main body is connected with the purification box main body through a connecting device. The device has the advantages that the device can be combined, transfer steps are reduced, and cleaning dead angles are not increased.
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Description

Technical Field

[0001] The utility model relates to the technical field of polyglutamic acid, in particular to a polyglutamic acid fermentation and purification device. Background Art

[0002] Polyglutamic acid (PGA) is a polymer material with numerous excellent properties and is widely used in cosmetics, food, and pharmaceuticals. PGA is a polymer composed of glutamic acid monomers linked by peptide bonds between α-amino and γ-carboxyl groups. Produced by microbial fermentation, PGA is water-soluble and biodegradable. PGA exhibits excellent moisturizing properties, 2-3 times that of hyaluronic acid, and is therefore widely used as a moisturizer in cosmetics. Due to the large number of free carboxyl groups in its molecular chain, PGA can form stable chelates with metal ions, which serve to adsorb heavy metal ions. PGA is completely biodegradable in the environment, producing non-toxic glutamic acid, making it an environmentally friendly polymer. Due to its excellent moisturizing properties and safety, PGA is often used as an ingredient in various skin care products, such as creams and serums. In the food industry, PGA can be used as a thickener and stabilizer to improve food texture and shelf life. PGA can also be used as a drug carrier to control drug release rate and enhance drug efficacy.

[0003] In the existing technology, polyglutamic acid needs to go through a laboratory culture process during the actual production process. During the culture process, polyglutamic acid needs to be fermented and purified. Specifically, in order to obtain clean polyglutamic acid raw materials, in order to optimize the relevant experimental equipment, we proposed a polyglutamic acid fermentation and purification device. Utility Model Content

[0004] The purpose of the utility model is to provide a polyglutamic acid fermentation and purification device to solve the problems existing in the prior art proposed by the above background technology.

[0005] In order to achieve the above purpose, the present invention adopts the following technical solutions:

[0006] A polyglutamic acid fermentation and purification device comprises a purification box body and a fermentation box body, the fermentation box body and the purification box body being arranged up and down, a top cover being provided at the upper end of the fermentation box body, a feeding device being fixedly connected to the lower end of the top cover, a connecting pipe being provided between the purification box body and the fermentation box body, an input pipe being fixedly connected to the upper end of the purification box body at a corresponding position, a filtering device being fixedly connected to the upper end of the input pipe, a sealing device being fixedly connected to the side wall of the input pipe, and the fermentation box body and the purification box body being connected via a connecting device.

[0007] Preferably, the unloading device includes an electric telescopic rod fixedly connected to the lower end of the top cover, and a plunger is fixedly connected to the lower end of the electric telescopic rod. The plunger is conical, and a through groove is provided at the inner bottom of the fermentation box body at the corresponding position, and the lower end of the plunger is located in the through groove.

[0008] Preferably, the filtering device includes two fixing columns fixedly connected to the upper end of the input pipe, and a filter disc is fixedly connected to the upper ends of the two fixing columns. A plurality of filter holes are provided through the inner bottom of the filter disc, and the filter disc is located in its entirety in the connecting pipe.

[0009] Preferably, the sealing device includes a second sealing ring fixedly connected to the side wall of the input pipe, the second sealing ring is located at the upper end of the purification box body, and the lower end of the connecting pipe at the corresponding position is fixedly connected with a first sealing ring, and the position of the first sealing ring corresponds to the position of the second sealing ring in the upper and lower directions.

[0010] Preferably, the connecting device includes a plurality of connecting columns fixedly connected to the upper end of the purification box body, the upper ends of the plurality of connecting columns are fixedly connected to positioning magnetic blocks, a plurality of positioning grooves are provided through the lower end of the fermentation box body at corresponding positions, the inner tops of the plurality of positioning grooves are fixedly connected to metal sheets, the positions of the plurality of connecting columns correspond to the positions of the plurality of positioning grooves, and the positions of the plurality of positioning magnetic blocks correspond to the positions of each metal sheet.

[0011] Preferably, the connecting pipe is connected to the lower end of the fermentation box body.

[0012] Compared with the prior art, the beneficial effects of the present invention are:

[0013] In the utility model, the purification box and the fermentation box are combined together by arranging a feeding device, a filtering device, a sealing device and a connecting device to cooperate with each other. The mixed liquid after fermentation in the fermentation box is directly filtered through the filter disk at the connecting pipe and then enters the purification box for purification operation. Combining the two together saves the relevant transfer steps. At the same time, the design is detachable and does not increase the difficulty of cleaning. BRIEF DESCRIPTION OF THE DRAWINGS

[0014] Figure 1 This is a schematic structural diagram of a polyglutamic acid fermentation and purification device proposed in the present invention;

[0015] Figure 2 This is a schematic diagram of the expanded fermentation tank body of a polyglutamic acid fermentation and purification device proposed in the present invention;

[0016] Figure 3 This is a schematic diagram of the top structure of the purification box body of a polyglutamic acid fermentation and purification device proposed in the utility model.

[0017] In the figure: 1 purification box body, 2 fermentation box body, 3 top cover, 4 connecting column, 5 connecting pipe, 6 electric telescopic rod, 7 plunger, 8 positioning magnetic block, 9 filter plate, 10 fixing column, 11 input pipe, 12 first sealing ring, 13 second sealing ring. DETAILED DESCRIPTION

[0018] The technical solutions in the embodiments of the present invention will be described clearly and completely below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, rather than all the embodiments.

[0019] Reference Figure 1-3 A polyglutamic acid fermentation and purification device includes a purification box body 1 and a fermentation box body 2. The fermentation box body 2 and the purification box body 1 are arranged up and down. A top cover 3 is provided at the upper end of the fermentation box body 2. A feeding device is fixedly connected to the lower end of the top cover 3. The feeding device includes an electric telescopic rod 6 fixedly connected to the lower end of the top cover 3. A plunger 7 is fixedly connected to the lower end of the electric telescopic rod 6. The plunger 7 is conical. A through groove is provided at the inner bottom of the fermentation box body 2 at the corresponding position, and the lower end of the plunger 7 is located in the through groove.

[0020] Among them, a connecting pipe 5 is commonly provided between the purification box main body 1 and the fermentation box main body 2, and the connecting pipe 5 is connected to the lower end of the fermentation box main body 2. The upper end of the purification box main body 1 at the corresponding position is fixedly connected with an input pipe 11, and the upper end of the input pipe 11 is fixedly connected to a filtering device. The filtering device includes two fixed columns 10 fixedly connected to the upper end of the input pipe 11, and the upper ends of the two fixed columns 10 are commonly fixedly connected to a filter disc 9. A plurality of filter holes are penetrated at the inner bottom of the filter disc 9, and the filter disc 9 is located as a whole in the connecting pipe 5.

[0021] Among them, a sealing device is fixedly connected to the side wall of the input pipe 11, and the sealing device includes a second sealing ring 13 fixedly connected to the side wall of the input pipe 11. The second sealing ring 13 is located at the upper end of the purification box body 1, and the lower end of the connecting pipe 5 at the corresponding position is fixedly connected with a first sealing ring 12. The position of the first sealing ring 12 corresponds to the position of the second sealing ring 13 up and down.

[0022] Specifically, the fermentation box body 2 and the purification box body 1 are connected by a connecting device, which includes a plurality of connecting columns 4 fixedly connected to the upper end of the purification box body 1, and the upper ends of the plurality of connecting columns 4 are fixedly connected to positioning magnetic blocks 8, and a plurality of positioning grooves are provided through the lower end of the fermentation box body 2 at corresponding positions, and the inner tops of the plurality of positioning grooves are fixedly connected to metal sheets, the positions of the plurality of connecting columns 4 correspond to the positions of the plurality of positioning grooves, and the positions of the plurality of positioning magnetic blocks 8 correspond to the positions of each metal sheet.

[0023] In the present invention, the operator can perform fermentation and purification operations respectively through the fermentation box body 2 and the purification box body 1. After the fermentation is completed, the mixed liquid can be transferred to the connecting pipe 5 below by driving the electric telescopic rod 6 to open the plunger 7. The mixed liquid in the connecting pipe 5 will be filtered by the filter disc 9 to initially filter out unnecessary impurities from the mixed liquid. The remaining mixed liquid will then enter the purification box body 1 for purification operation.

[0024] When the device needs to be cleaned, it is only necessary to separate the fermentation tank body 2 from the purification tank body 1 to expose the internal added related structures. The operator can clean it directly without creating additional cleaning dead corners.

[0025] The above is only a preferred specific implementation method of the present invention, but the protection scope of the present invention is not limited to this. Any technician familiar with the technical field within the technical scope disclosed by the present invention can make equivalent replacements or changes based on the technical solution and utility model concept of the present invention, which should be covered by the protection scope of the present invention.

Claims

1. A polyglutamic acid fermentation and purification device, comprising a purification tank body (1) and a fermentation tank body (2), characterized in that: The fermentation box body (2) and the purification box body (1) are arranged up and down, a top cover (3) is provided at the upper end of the fermentation box body (2), a feeding device is fixedly connected to the lower end of the top cover (3), a connecting pipe (5) is commonly provided between the purification box body (1) and the fermentation box body (2), an input pipe (11) is fixedly connected to the upper end of the purification box body (1) at a corresponding position, a filtering device is fixedly connected to the upper end of the input pipe (11), a sealing device is fixedly connected to the side wall of the input pipe (11), and the fermentation box body (2) and the purification box body (1) are connected via a connecting device.

2. A polyglutamic acid fermentation and purification device according to claim 1, characterized in that: The unloading device comprises an electric telescopic rod (6) fixedly connected to the lower end of the top cover (3); a plunger (7) is fixedly connected to the lower end of the electric telescopic rod (6); the plunger (7) is conical; a through groove is provided through the inner bottom of the fermentation box body (2) at a corresponding position, and the lower end of the plunger (7) is located in the through groove.

3. A polyglutamic acid fermentation and purification device according to claim 1, characterized in that: The filtering device comprises two fixing columns (10) fixedly connected to the upper end of the input pipe (11), a filter disc (9) being fixedly connected to the upper ends of the two fixing columns (10), a plurality of filter holes being provided through the inner bottom of the filter disc (9), and the filter disc (9) being entirely located in the connecting pipe (5).

4. A polyglutamic acid fermentation and purification device according to claim 1, characterized in that: The sealing device comprises a second sealing ring (13) fixedly connected to the side wall of the input pipe (11), the second sealing ring (13) being located at the upper end of the purification box body (1), and a first sealing ring (12) being fixedly connected to the lower end of the connecting pipe (5) at a corresponding position, the position of the first sealing ring (12) corresponding to the position of the second sealing ring (13) in the upper and lower directions.

5. A polyglutamic acid fermentation and purification device according to claim 1, characterized in that: The connecting device includes a plurality of connecting columns (4) fixedly connected to the upper end of the purification box body (1), the upper ends of the plurality of connecting columns (4) are fixedly connected with positioning magnetic blocks (8), the lower end of the fermentation box body (2) at corresponding positions is provided with a plurality of positioning grooves, the inner tops of the plurality of positioning grooves are fixedly connected with metal sheets, the positions of the plurality of connecting columns (4) respectively correspond to the positions of the plurality of positioning grooves, and the positions of the plurality of positioning magnetic blocks (8) respectively correspond to the positions of the respective metal sheets.

6. A polyglutamic acid fermentation and purification device according to claim 1, characterized in that: The connecting pipe (5) is connected to the lower end of the fermentation box body (2).