Biopharmaceutical extracting solution filtering device

Abstract

The utility model discloses a biopharmaceutical extracting solution filtering device, which relates to the technical field of biopharmacy and comprises a filtering barrel, a fixing ring is fixedly mounted on the inner wall of the filtering barrel, a pipette is fixedly mounted on the inner wall of the fixing ring, a filter screen is fixedly mounted at the top of the inner wall of the pipette, and a one-way valve I is rotatably connected to the top end of the pipette. A piston is slidably mounted on the inner wall of the filter barrel and 10cm away from the top of the one-way valve I, a fixing ring is fixedly mounted on the inner wall of the piston, and a one-way valve II is rotatably mounted on the top of the fixing ring; according to the utility model, the piston is driven by the electric telescopic rod to reciprocate up and down, so that the automatic filtration of the extracting solution and the automatic discharge of residues are realized, the residues in the extracting solution are effectively intercepted by the filter screen, and the residues automatically fall into the collecting tray under the action of gravity, so that the subsequent cleaning is convenient, and the filter screen does not need to be frequently disassembled; therefore, the filtering efficiency is improved, and the risk of pollution caused by disassembly and assembly is reduced.

Description

Technical Field

[0001] The utility model relates to the technical field of biopharmaceuticals, in particular to a biopharmaceutical extract filtering device. Background Art

[0002] In the field of biopharmaceuticals, the filtration of extracts is a crucial link, which is directly related to the purity and quality of the product. With the continuous development of biotechnology and the increasing complexity of biopharmaceutical processes, the requirements for extract filtration devices are becoming higher and higher.

[0003] During the filtration process, traditional filtration devices easily adhere to the filter surface due to drug residues, so deep cleaning is performed by disassembling the filter. However, the filter disassembly process is often complicated and time-consuming, requiring specialized tools and techniques. Frequent disassembly may also damage the sealing and stability of the filter. Disassembling and reinstalling the filter may also introduce additional pollution risks and have an adverse impact on the production environment.

[0004] In view of this, this application is hereby filed. Utility Model Content

[0005] The purpose of the present utility model is to provide a biopharmaceutical extract filtering device to solve the problems raised in the above background technology.

[0006] In order to solve the above technical problems, the utility model provides a biopharmaceutical extract filtering device, including a filter barrel, a fixing ring is fixedly installed on the inner wall of the filter barrel, a pipette is fixedly installed on the inner wall of the fixing ring, a filter is fixedly installed on the top of the inner wall of the pipette, a one-way valve is rotatably connected to the top of the pipette, a piston is slidably installed on the inner wall of the filter barrel 10 cm from the top of the one-way valve, a fixing ring is fixedly installed on the inner wall of the piston, a one-way valve 2 is rotatably installed on the top of the fixing ring, a piston rod is fixedly installed on the outer wall of the piston, a pull rod is fixedly installed on the top of the pull rod, an electric telescopic rod is fixedly installed on the top of the electric telescopic rod, a fixing rod is fixedly installed on the top of the electric telescopic rod, both ends of the fixed rod are fixedly installed on the top of the inner wall of the filter barrel, and a collection plate is slidably installed on the bottom of the filter barrel.

[0007] Furthermore, a connecting plate 1 is fixedly installed on the top of the suction tube, a rotating shaft is fixedly installed on the inner wall of the connecting plate 1, the rotating shaft is rotatably connected to a connecting plate 2 near the outer wall of the connecting plate 1, and the end of the connecting plate 2 away from the rotating shaft is fixedly installed on the side wall of the one-way valve 1.

[0008] Furthermore, a defoaming net is fixedly installed on the inner wall of the fixing ring, and the intervals between the defoaming nets are 1 to 2 cm.

[0009] Furthermore, a liquid inlet pipe is fixedly installed on the outer wall of the bottom end of the filter barrel, and a liquid outlet pipe is fixedly installed on the outer wall of the top end of the filter barrel away from the liquid inlet pipe.

[0010] Furthermore, a sealing disk is fixedly mounted on the inner wall of the filter barrel, and a pull rod is slidably connected to the inner wall of the sealing disk.

[0011] Furthermore, a fixing frame is fixedly installed on the outer wall of the filter barrel, a supporting frame is fixedly installed on the side wall of the fixing frame, and a base is fixedly installed on the bottom of the supporting frame.

[0012] Furthermore, the collecting tray is made of glass, and a sealing ring is provided between the top of the collecting tray and the bottom of the filter barrel.

[0013] Compared with the existing technology, the beneficial effects of the utility model are: the device drives the piston to move up and down reciprocatingly through the electric telescopic rod, thereby realizing automatic filtration of the extract and automatic discharge of the residue. The filter screen effectively intercepts the residue in the extract, and the residue automatically falls into the collection tray under the action of gravity, which is convenient for subsequent cleaning and does not require frequent disassembly of the filter screen, thereby improving the filtration efficiency and reducing the risk of contamination due to disassembly and assembly. BRIEF DESCRIPTION OF THE DRAWINGS

[0014] Figure 1 This is a schematic diagram of the cross-sectional structure of a biopharmaceutical extract filtration device;

[0015] Figure 2 This is a schematic diagram of the piston structure of a biopharmaceutical extract filtration device;

[0016] Figure 3 for Figure 2 Schematic diagram of the enlarged structure at A in the middle;

[0017] Figure 4 This is a schematic diagram of the front structure of a biopharmaceutical extract filtration device.

[0018] In the figure: 1. Base; 2. Support frame; 3. Fixed frame; 4. Filter barrel; 5. Liquid inlet pipe; 6. Liquid outlet pipe; 7. Collecting tray; 8. Fixed ring; 9. Liquid suction pipe; 10. Filter screen; 11. Piston; 12. One-way valve 1; 13. One-way valve 2; 14. Piston rod; 15. Pull rod; 16. Sealing disk; 17. Electric telescopic rod; 18. Fixed rod; 19. Defoaming net; 20. Connecting plate 1; 21. Connecting plate 2; 22. Rotating shaft; 23. Fixed ring. DETAILED DESCRIPTION

[0019] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the embodiments described are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative efforts are within the scope of protection of the present invention.

[0020] See also Figure 1 - Figure 4 The utility model provides a technical solution: a biopharmaceutical extract filtering device, including a filter barrel 4, a fixed ring 8 is fixedly installed on the inner wall of the filter barrel 4, a liquid suction pipe 9 is fixedly installed on the inner wall of the fixed ring 8, a filter screen 10 is fixedly installed on the top of the inner wall of the liquid suction pipe 9, and a one-way valve 12 is rotatably connected to the top of the liquid suction pipe 9. A piston 11 is slidably installed on the inner wall of the filter barrel 4 at 10 cm from the top of the one-way valve 12, a fixed ring 23 is fixedly installed on the inner wall of the piston 11, and a one-way valve 2 13 is rotatably installed on the top of the fixed ring 23. A piston rod 14 is fixedly installed on the outer wall of the piston 11, a pull rod 15 is fixedly installed on the top of the piston rod 14, an electric telescopic rod 17 is fixedly installed on the top of the pull rod 15, a fixed rod 18 is fixedly installed on the top of the electric telescopic rod 17, both ends of the fixed rod 18 are fixedly installed on the top of the inner wall of the filter barrel 4, and a collecting tray 7 is slidably installed on the bottom of the filter barrel 4.

[0021] It should be noted that the electric telescopic rod 17 drives the piston 11 to move up and down, and cooperates with the switching action of the one-way valve 12 and the one-way valve 2 13 to realize the automatic circulation filtration of the extract. The residue generated during the filtration process will be intercepted by the filter 10, and the residue will automatically fall into the collection tray 7 under the influence of gravity, thereby avoiding the contamination of the residue on the filter barrel 4 and the influence on the quality of the extract.

[0022] See also Figure 3 The utility model provides a technical solution: a biopharmaceutical extract filtering device, including a connecting plate 20 fixedly installed on the top of a pipette 9, a rotating shaft 22 fixedly installed on the inner wall of the connecting plate 20, and a connecting plate 21 rotatably connected to the outer wall of the rotating shaft 22 close to the connecting plate 20. The end of the connecting plate 21 away from the rotating shaft 22 is fixedly installed on the side wall of the one-way valve 12.

[0023] It should be noted that the connection between connecting plate 1 20, connecting plate 2 21 and rotating shaft 22 provides a more stable foundation for one-way valve 12, which can effectively reduce the loosening or deviation of one-way valve 12 caused by liquid flow or external factors, thereby ensuring the stability and reliability of the filtering device.

[0024] See also Figure 2The utility model provides a technical solution: a biopharmaceutical extract filtering device, comprising a fixing ring 23 with a defoaming net 19 fixedly mounted on the inner wall thereof, and the intervals between the defoaming nets 19 are 1 to 2 cm.

[0025] It should be noted that the presence of the defoaming net 19 can effectively intercept and disperse the bubbles in the extracted extract, causing them to gradually dissipate or burst, thereby significantly reducing the bubble content in the filtered extract and improving the purity and stability of the extract.

[0026] See also Figure 1 The utility model provides a technical solution: a biopharmaceutical extract filtering device, comprising a filter barrel 4 with a liquid inlet pipe 5 fixedly mounted on the outer wall at the bottom end, and a liquid outlet pipe 6 fixedly mounted on the outer wall at the top end of the filter barrel 4 away from the liquid inlet pipe 5.

[0027] It should be noted that the liquid inlet pipe 5 is located at the bottom, which facilitates the extraction liquid to flow directly into the filter barrel 4, reducing liquid splashing and waste, and the liquid outlet pipe 6 is set at the top, which can ensure that the filtered liquid can flow out smoothly and efficiently, forming a natural upward filtration and downward discharge process, thereby improving the filtration efficiency.

[0028] See also Figure 1 The utility model provides a technical solution: a biopharmaceutical extract filtering device, comprising a filter barrel 4 with a sealing disk 16 fixedly mounted on the inner wall thereof, and a pull rod 15 slidably connected to the inner wall of the sealing disk 16 .

[0029] It should be noted that the presence of the sealing disk 16 effectively isolates the direct contact between the inside of the filter barrel 4 and the external environment, reducing the risk of liquid leakage. At the same time, the sliding connection design with the pull rod 15 ensures that the sealing performance is not affected during the up and down movement of the piston 11, thereby ensuring the continuity and stability of the filtration process.

[0030] See also Figure 4 The utility model provides a technical solution: a biopharmaceutical extract filtering device, comprising a filter barrel 4 with a fixing frame 3 fixedly mounted on the outer wall, a support frame 2 fixedly mounted on the side wall of the fixing frame 3, and a base 1 fixedly mounted on the bottom of the support frame 2.

[0031] It should be noted that the filter barrel 4 is firmly mounted on the support frame 2 through the fixing frame 3, and the base 1 provides solid support, which greatly enhances the stability of the entire filtering device. Even if a large vibration or impact occurs during the filtration process, it can ensure that the filter barrel 4 remains stable and avoids tipping over or damage.

[0032] See also Figure 1The utility model provides a technical solution: a biopharmaceutical extract filtering device, including a collecting tray 7 made of glass, and a sealing ring is provided between the top of the collecting tray 7 and the bottom of the filter barrel 4.

[0033] It should be noted that glass has excellent corrosion resistance and can resist the erosion of various chemical substances. In the field of biopharmaceuticals, the extract may contain various acids, bases or organic solvents. The collection tray 7 can effectively protect its interior from corrosion, ensuring that the collected residues or waste liquids do not react with the container, thereby ensuring the purity and safety of the product.

[0034] Furthermore, a sealing ring is provided between the collecting tray 7 and the bottom of the filter barrel 4 to ensure a tight connection between the two, prevent liquid leakage, protect the equipment and working environment from pollution, and ensure the continuity and stability of the filtration process.

[0035] Working principle: The extract flows into the inner wall of the filter barrel 4 through the liquid inlet pipe 5, and the electric telescopic rod 17 is started at this time, driving the electric telescopic rod 17 to reciprocate and extend, driving the piston 11 to slide upward. At this time, the internal air pressure closes the one-way valve 2 13 and the fixed ring 23, and at the same time opens the one-way valve 12, and the extract at the bottom of the filter barrel 4 is pumped through the liquid pipe 9 to the middle of the fixed ring 8 and the piston 11. At this time, the electric telescopic rod 17 extends downward, so that the one-way valve 2 13 opens and the one-way valve 12 automatically closes, The extract is squeezed to the top of the piston 11, and the electric telescopic rod 17 retracts upward, driving the piston 11 upward while closing the one-way valve 2 13, lifting the extract to the same height as the liquid outlet pipe 6 and flowing out. In this process, the residue inside the extract is intercepted by the filter 10 and falls to the top of the collection tray 7 under the influence of gravity. When the extract is filtered, it is only necessary to pull out the collection tray 7 and pour out the residue inside. The device does not require frequent disassembly of the filter, which improves the filtration efficiency while avoiding the introduction of additional pollution risks due to frequent disassembly and assembly.

Claims

1. A biopharmaceutical extract filtering device, comprising a filter barrel (4), characterized in that: A fixing ring (8) is fixedly installed on the inner wall of the filter barrel (4), a liquid suction pipe (9) is fixedly installed on the inner wall of the fixing ring (8), a filter screen (10) is fixedly installed on the top of the inner wall of the liquid suction pipe (9), a one-way valve (12) is rotatably connected to the top of the liquid suction pipe (9), a piston (11) is slidably installed on the inner wall of the filter barrel (4) at a position 10 cm from the top of the one-way valve (12), a fixing ring (23) is fixedly installed on the inner wall of the piston (11), a one-way valve (13) is rotatably installed on the top of the fixing ring (23), a piston rod (14) is fixedly installed on the outer wall of the piston (11), a pull rod (15) is fixedly installed on the top of the piston rod (14), an electric telescopic rod (17) is fixedly installed on the top of the pull rod (15), a fixing rod (18) is fixedly installed on the top of the electric telescopic rod (17), both ends of the fixing rod (18) are fixedly installed on the top of the inner wall of the filter barrel (4), and a collecting plate (7) is slidably installed on the bottom of the filter barrel (4).

2. A biopharmaceutical extract filtration device according to claim 1, characterized in that: A connecting plate 1 (20) is fixedly mounted on the top of the liquid suction tube (9), a rotating shaft (22) is fixedly mounted on the inner wall of the connecting plate 1 (20), the rotating shaft (22) is rotatably connected to a connecting plate 2 (21) near the outer wall of the connecting plate 1 (20), and one end of the connecting plate 2 (21) away from the rotating shaft (22) is fixedly mounted on the side wall of the one-way valve 1 (12).

3. The biopharmaceutical extract filtration device according to claim 1, wherein: A defoaming net (19) is fixedly mounted on the inner wall of the fixing ring (23), and the intervals between the defoaming nets (19) are 1 to 2 cm.

4. The biopharmaceutical extract filtration device according to claim 1, wherein: A liquid inlet pipe (5) is fixedly mounted on the outer wall of the bottom end of the filter barrel (4), and a liquid outlet pipe (6) is fixedly mounted on the outer wall of the top end of the filter barrel (4) away from the liquid inlet pipe (5).

5. The biopharmaceutical extract filtration device according to claim 1, characterized in that: A sealing disc (16) is fixedly mounted on the inner wall of the filter barrel (4), and a pull rod (15) is slidably connected to the inner wall of the sealing disc (16).

6. The biopharmaceutical extract filtration device according to claim 1, characterized in that: A fixing frame (3) is fixedly mounted on the outer wall of the filter barrel (4), a support frame (2) is fixedly mounted on the side wall of the fixing frame (3), and a base (1) is fixedly mounted on the bottom of the support frame (2).

7. The biopharmaceutical extract filtration device according to claim 1, characterized in that: The material of the collecting tray (7) is glass, and a sealing ring is provided between the top of the collecting tray (7) and the bottom of the filter barrel (4).

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