Neutrophil CD64 labeled sample preservation device
By designing a sample storage device marked with neutrophil CD64, using structures such as storage boxes, carrier tables, temperature insulation boards and refrigeration chambers, the low temperature environment and isolation problems in sample storage are solved, ensuring the stability and activity of the test tubes, and improving the detection effect.
Patent Information
- Application Number
- CN202422165951.6
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-09-04
- Publication Date
- 2025-09-02
- Estimated Expiration
- 2034-09-04
AI Technical Summary
In the prior art, the storage device of CD64 marking samples cannot guarantee a low temperature environment and cannot be isolated from the outside world, resulting in adverse storage and affecting the detection effect.
A sample storage device marked with neutrophil CD64 was designed, including a storage box, a carrier, a temperature insulation board, a mounting rack and a refrigeration chamber. The test tube was fixed by a support plate and a rubber block, and the sealing strip and a temperature insulation board were combined to ensure the seal, and a low temperature environment was maintained using a refrigerator.
The stability of the test tube and the maintenance of the low-temperature environment during transportation are achieved, the activity of the sample is ensured, and reliable storage conditions are provided for subsequent testing.
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Figure CN223291336U_ABST
Abstract
Description
Technical Field
[0001] The utility model belongs to the technical field of sample preservation, and in particular relates to a sample preservation device marked with neutrophil CD64. Background Art
[0002] CD64, also known as Fc-gamma receptor protein 1 (FcyRI), is lowly expressed on the surface of peripheral blood neutrophils. Upon infection, stimulatory factors such as bacterial cell wall lipopolysaccharide, granulocyte colony-stimulating factor, and interferon can rapidly shift the expression of CD64 on neutrophils from low to high levels, activating neutrophils. Therefore, it is used as an indicator of infection.
[0003] The storage of CD64-labeled samples requires a low-temperature environment to ensure their activity and facilitate subsequent testing. However, in the existing technology, there is no dedicated storage device for the storage of CD64-labeled samples. Instead, a unified storage device is used for storage. As a result, the required low temperature cannot be guaranteed to meet the usage requirements, and the isolation requirement between the box and the outside world may not be met, resulting in unfavorable storage of CD64-labeled samples and poor detection results.
[0004] To sum up, the above technical problems need to be solved. Utility Model Content
[0005] The purpose of the utility model is to provide a neutrophil CD64-labeled sample storage device to solve the problem that low temperature cannot meet the use requirements and the box may not be isolated from the outside world.
[0006] To achieve the above-mentioned purpose, the present invention provides the following technical solution: a sample storage device for neutrophil CD64 labeling, comprising a storage box, a carrying platform is provided inside the storage box, an insulation board is fixedly connected to the inner wall of the storage box, a mounting rack is provided inside the carrying platform, a test tube is movably connected to the mounting rack, and a refrigeration chamber is provided on the carrying platform.
[0007] Preferably, a groove is provided on the outer wall of the upper side of the supporting platform, the mounting frame is movably installed at the upper end of the groove, an opening is provided on the mounting frame, a support plate is movably installed on the inner wall of the opening, and the support plate is movably connected to the outer wall of the test tube.
[0008] Preferably, the inner wall of the opening is symmetrically provided with mounting grooves, springs are provided in the mounting grooves, a slide rod is provided on the support plate, the slide rod is slidably installed in the mounting groove, and one end is fixedly connected to the spring.
[0009] Preferably, the outer wall of the support plate is provided with a rubber block, and the rubber block is movably connected to the outer wall of the test tube.
[0010] Preferably, a refrigerator is fixedly connected in the refrigeration bin, a fixing plate is provided at the port of the refrigeration bin, a mounting port is provided on the fixing plate, and a bolt is threadedly connected to the mounting port.
[0011] Preferably, an opening and closing door is rotatably mounted on the storage box, a sealing strip is provided on the inner wall of one side of the opening and closing door, a connecting groove is provided on the insulation board, and the sealing strip is movably connected to the connecting groove.
[0012] Preferably, a handle is provided on the opening and closing door.
[0013] The technical effects and advantages of the present invention are as follows: after collecting samples, the samples can be stored in test tubes, and the test tubes can be placed on the mounting rack. The outer walls of the test tubes on opposite sides can be clamped by the support plates arranged on the mounting rack, and the resistance can be increased by the resistance of the rubber blocks to prevent the test tubes from shaking. Then, the refrigerator can be turned on to cool the grooves arranged on the carrier platform, thereby cooling the test tubes. The carrier platform can then be slid to the interior of the storage box, and the opening and closing door can be closed. The sealing strip is connected to the connecting groove, so that the storage box is in a sealed state, and the gas inside the storage box is isolated from the external gas. The outer wall on one side of the opening and closing door is abutted against the outer wall of the carrier platform, so that the carrier platform is in a stable state, thereby ensuring the stability of the carrier platform during transportation, thereby ensuring the stability of the test tubes. BRIEF DESCRIPTION OF THE DRAWINGS
[0014] Figure 1 It is a schematic diagram of the three-dimensional structure of the utility model;
[0015] Figure 2 This is a schematic diagram of the installation of the load-bearing platform of the present utility model;
[0016] Figure 3 This is a schematic top cross-sectional view of the storage box of the present utility model;
[0017] Figure 4 It is a side sectional schematic diagram of the device of the present utility model.
[0018] In the figure: 1. Storage box; 2. Carrying platform; 3. Insulation board; 4. Mounting frame; 5. Test tube; 6. Refrigeration chamber; 7. Groove; 8. Opening; 9. Support plate; 10. Mounting slot; 11. Spring; 12. Slide bar; 13. Rubber block; 14. Refrigerator; 15. Mounting port; 16. Bolt; 17. Opening and closing door; 18. Sealing strip; 19. Connecting slot; 20. Handle; 21. Fixing plate. DETAILED DESCRIPTION
[0019] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the embodiments described are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative efforts are within the scope of protection of the present invention.
[0020] The utility model provides Figure 1-4 The neutrophil CD64-labeled sample storage device shown in the figure includes a storage box 1, a supporting platform 2 is provided inside the storage box 1, a thermal insulation board 3 is fixedly connected to the inner wall of the storage box 1, a mounting frame 4 is provided inside the supporting platform 2, a test tube 5 is movably connected to the mounting frame 4, and a refrigeration chamber 6 is provided on the supporting platform 2. A refrigerator 14 is fixedly connected to the refrigeration chamber 6, and a fixing plate 21 is provided at the port of the refrigeration chamber 6. The fixing plate 21 is provided with a mounting port 15, and a bolt 16 is threadedly connected to the mounting port 15. After collecting the sample, the sample can be stored in the test tube 5, and the test tube 5 can be placed on the mounting rack 4. The outer walls of the test tube 5 on both sides are clamped by the support plates 9 provided on the mounting rack 4, and the resistance is increased by the resistance of the rubber block 13 to prevent the test tube 5 from shaking. Then the refrigerator 14 is turned on to cool the groove 7 provided on the supporting platform 2, and then the test tube 5 is cooled. The supporting platform 2 is then slid to the inside of the storage box 1, and the opening and closing door 17 is closed. The sealing strip 18 is connected to the connecting groove 19, so that the storage box 1 is in a sealed state, and the gas inside the storage box 1 is isolated from the external gas. The outer wall on one side of the opening and closing door 17 is against the outer wall of the supporting platform 2, so that the supporting platform 2 is in a stable state, so as to ensure the stability of the supporting platform 2 during transportation, and thus ensure the stability of the test tube 5.
[0021] Specifically, the outer wall of the upper side of the support platform 2 is provided with a groove 7, and the mounting frame 4 is movably mounted at the upper end of the groove 7. The mounting frame 4 is provided with an opening 8, and a support plate 9 is movably mounted on the inner wall of the opening 8. The support plate 9 is movably connected to the outer wall of the test tube 5. The inner wall of the opening 8 is symmetrically provided with mounting grooves 10, each of which is provided with a spring 11. The support plate 9 is provided with a slide bar 12, which is slidably mounted in the mounting groove 10 and fixedly connected to the spring 11 at one end. The outer wall of the support plate 9 is provided with a rubber block 13, which is movably connected to the outer wall of the test tube 5. When in use, the mounting bracket 4 can be placed at the end of the groove 7 provided on the supporting platform 2, and the test tube 5 is fixed by the supporting plates 9 arranged opposite to each other in the opening 8, so that it always remains in a vertical state. Mounting grooves 10 are symmetrically provided on the inner walls opposite to the opening 8, and the support plates 9 are installed in the mounting grooves 10 through sliding grooves, so that the support plates 9 can slide horizontally, and the force of the springs 11 ensures that when the test tube 5 is placed inside the two supporting plates 9, the inner walls on the opposite sides of the test tube 5 are clamped, and the rubber blocks 13 are used to further ensure the stability of the test tube 5.
[0022] Specifically, an opening and closing door 17 is rotatably mounted on the storage box 1. A sealing strip 18 is provided on the inner wall of one side of the opening and closing door 17. A connecting groove 19 is provided on the insulation board 3. The sealing strip 18 is movably connected to the connecting groove 19. A handle 20 is provided on the opening and closing door 17. The opening and closing door 17 is hinged on the storage box 1 and is provided with a locking device so that it can remain fixedly connected to the storage box 1 when closed. When closed, the opening 8 of the storage box 1 is sealed by connecting to the connecting groove 19 via a rubber strip to ensure that the storage box 1 remains isolated by the insulation board 3 provided therein, ensuring a stable storage environment for the test tubes 5 containing samples therein. The locking device can be a locking block rotatably mounted on the opening and closing door 17. The locking block cooperates with a bayonet provided on the storage box 1 to ensure that the opening and closing door 17 remains fixedly connected to the storage box 1 when closed.
[0023] Finally, it should be noted that the above is only a preferred embodiment of the present invention and is not intended to limit the present invention. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art can still modify the technical solutions described in the aforementioned embodiments or make equivalent replacements for some of the technical features therein. Any modifications, equivalent replacements, improvements, etc. made within the spirit and principles of the present invention should be included in the scope of protection of the present invention.
Claims
1. A sample storage device for neutrophil CD64 labeling, characterized by: The invention comprises a storage box (1), wherein a carrying platform (2) is provided inside the storage box (1), a temperature-isolating plate (3) is fixedly connected to the inner wall of the storage box (1), a mounting frame (4) is provided inside the carrying platform (2), a test tube (5) is movably connected to the mounting frame (4), and a refrigeration chamber (6) is provided on the carrying platform (2).
2. The neutrophil CD64-labeled sample storage device according to claim 1, characterized in that: A groove (7) is provided on the outer wall of the upper side of the supporting platform (2); the mounting frame (4) is movably mounted on the upper end of the groove (7); an opening (8) is provided on the mounting frame (4); a support plate (9) is movably mounted on the inner wall of the opening (8); and the support plate (9) is movably connected to the outer wall of the test tube (5).
3. The neutrophil CD64-labeled sample storage device according to claim 2, characterized in that: The inner wall of the opening (8) is symmetrically provided with mounting grooves (10), and springs (11) are provided in the mounting grooves (10). A sliding rod (12) is provided on the support plate (9), and the sliding rod (12) is slidably installed in the mounting groove (10), and one end of the sliding rod is fixedly connected to the spring (11).
4. The neutrophil CD64-labeled sample storage device according to claim 3, characterized in that: The outer wall of the support plate (9) is provided with a rubber block (13), and the rubber block (13) is movably connected to the outer wall of the test tube (5).
5. The neutrophil CD64-labeled sample storage device according to claim 1, characterized in that: A refrigerator (14) is fixedly connected in the refrigeration bin (6), a fixing plate (21) is provided at the port of the refrigeration bin (6), a mounting port (15) is provided on the fixing plate (21), and a bolt (16) is threadedly connected to the mounting port (15).
6. The neutrophil CD64-labeled sample storage device according to claim 5, characterized in that: An opening and closing door (17) is rotatably mounted on the storage box (1), a sealing strip (18) is provided on the inner wall of one side of the opening and closing door (17), a connecting groove (19) is provided on the insulation board (3), and the sealing strip (18) is movably connected to the connecting groove (19).
7. The neutrophil CD64-labeled sample storage device according to claim 6, characterized in that: The opening and closing door (17) is provided with a handle (20).